CN115721797A - Wearable artificial kidney waste peritoneal dialysis solution circulating treatment system - Google Patents

Abstract

The invention discloses a wearable artificial kidney waste peritoneal dialysis solution circulating treatment system. The spent dialysate drained from the patient's peritoneal cavity is filtered and the fluid is separated into spent peritoneal dialysis concentrate and filtered fluid during the filtration process. The waste peritoneal dialysis concentrated solution is depressurized through the pressure reducing valve and flows back to the waste peritoneal dialysis solution bag again to be circularly processed, so that the filtering effect of the waste peritoneal dialysis solution is improved, and the discarding rate of the waste peritoneal dialysis solution is reduced. Because the waste peritoneal dialysis solution is discarded by patients who are continuously subjected to ambulatory peritoneal dialysis and patients who are treated by using automated peritoneal dialysis, the invention is mainly applied to wearable artificial extrarenal circulation equipment with high requirements on light weight and portability.

Description

Wearable artificial kidney waste peritoneal dialysis solution circulating treatment system

Technical Field

The invention relates to the field of peritoneal dialysis, in particular to a wearable artificial kidney waste peritoneal dialysis solution circulating treatment system.

Background

Renal insufficiency or failure, particularly in the end-stage renal disease, results in the body's loss of the ability to excrete water and minerals, excrete harmful metabolites, maintain acid-base balance, and control electrolyte and mineral concentrations within physiological ranges. Without replacing the filtering function of the kidney, toxic uremic waste metabolites including urea, creatinine, uric acid, etc. accumulated in body tissues can cause death of the patient.

Patients with insufficient kidney function or renal failure require dialysis or kidney transplantation for survival, which is the most desirable treatment if successful because it restores continuous kidney function and returns the patient to normal or near normal life, but most patients still choose dialysis treatment due to insufficient organ donation donors.

The conventional blood purification method requires the patient to frequently visit the hospital for a long time, so that the patient cannot return to the society to create value, the personal freedom is limited, meanwhile, compared with the continuous working mode of the healthy kidney, the discontinuity of the purified blood causes the low efficiency of removing the uremic toxins, the liquid and the uremic toxins are accumulated in the dialysis interval, and then the concentration of the liquid, the uremic toxins and the electrolyte is rapidly changed in the dialysis process, which is far away from the stable internal environment maintained by the healthy kidney, so that the dialysis quality is far from the expected level.

Peritoneal dialysis is another type of dialysis treatment for replacing kidney function that infuses sterile, pyrogen-free dialysate into the patient's peritoneal cavity. The peritoneum acts as a natural dialyzer and toxic uremic waste metabolites and various ions diffuse through the peritoneal membrane from the patient's bloodstream into the dialysate through the osmotic gradient. Peritoneal dialysis treatment requires removal, disposal, and replacement of the dialysate with fresh dialysate in a semi-continuous or continuous manner. Although not all peritoneal dialysis systems require medical monitoring at a treatment center, the large volumes of solution required for peritoneal dialysis are still inconvenient, cumbersome and expensive to drain, discard and replace.

To address this problem, there has been an increasing interest in developing portable renal replacement therapy devices since the 80's of the 20 th century, but no device has been devised that is both continuously operable and effective in removing uremic waste metabolites, yet small enough and/or light enough to be practically comfortably worn by a patient.

Peritoneal dialysis devices can be designed to be worn on patients with kidney disease. It is desirable that wearable peritoneal dialysis devices be lightweight, small in size, and yet still provide the desired functional and therapeutic benefits. Any reduction in size and weight of the wearable peritoneal dialysis device can make the wearable device more comfortable to wear and less cumbersome. Smaller and lighter wearable devices can greatly improve the quality of life of patients wearing the wearable peritoneal dialysis device.

In the present stage, a patient who uses peritoneal dialysis treatment needs to exchange 10 to 20L of dialysis solution for many times every day, and if the peritoneal dialysis device is worn on a patient suffering from renal disease, how to recycle the waste peritoneal dialysis solution discharged from the patient is a problem that the waste peritoneal dialysis solution cannot be bypassed.

Disclosure of Invention

The invention aims to provide a wearable artificial kidney waste peritoneal dialysis solution circulation treatment system.

The technical solution for realizing the purpose of the invention is as follows: a wearable artificial kidney waste peritoneal dialysis solution circulation treatment system comprises

One or more inlets connected to a means for providing inflow and outflow into the abdominal cavity of the patient;

a volume of spent peritoneal dialysis solution containing uremic waste metabolites that have diffused into the peritoneal dialysis solution in the patient's body;

at least one closed-loop fluid circuit carrying spent dialysate from the vessel that has not been completely filtered;

at least one pump connected in a closed-loop fluid circuit for pressurizing a volume of spent peritoneal dialysis solution. And the pressurized waste peritoneal dialysis solution is conveyed to a filtering system;

a filtration system connected in a fluid system loop, the filtration system removing at least one toxin from the spent peritoneal dialysis solution;

at least one pressure relief valve connected in the closed-loop fluid circuit for relieving pressure to spent dialysate that has passed through the filtration system but has not yet been completely filtered. And flowing the depressurized spent peritoneal dialysis solution into a spent peritoneal dialysis solution storage device.

Further, the filtration process separates the spent peritoneal dialysis solution into a spent peritoneal dialysis concentrate and a filtered liquid.

Further, the closed-loop fluid circuit includes at least one bifurcated fluid passageway for discharging spent peritoneal dialysis concentrate. The passage is communicated and disconnected by a solenoid valve or other devices for controlling the on-off state.

Compared with the prior art, the invention has the following remarkable advantages: the invention can ensure the purification quality of the waste peritoneal dialysis solution and reduce the waste of the waste peritoneal dialysis solution. The invention filters the waste dialysate drained from the abdominal cavity of a patient, separates fluid into waste peritoneal dialysis concentrated solution and filtered liquid in the filtering process, reduces the pressure of the waste peritoneal dialysis concentrated solution through the pressure reducing valve, and returns the waste peritoneal dialysis concentrated solution to the waste peritoneal dialysis solution bag for circular treatment, thereby improving the filtering effect of the waste peritoneal dialysis solution and reducing the discarding rate of the waste peritoneal dialysis solution.

Drawings

Fig. 1 is a schematic structural diagram of a wearable artificial kidney peritoneal dialysis solution circulation treatment system according to an embodiment of the invention.

Detailed Description

The wearable artificial kidney waste peritoneal dialysis solution circulating treatment system filters waste peritoneal dialysis solution drained from the abdominal cavity of a patient, and separates fluid into waste peritoneal dialysis concentrated solution and filtered liquid in the filtering process. The pressure of the waste peritoneal dialysis concentrated solution is reduced through a pressure reducing valve, the waste peritoneal dialysis concentrated solution flows back to the waste peritoneal dialysis solution bag again for circulation treatment, and the method is realized through the following technical scheme:

a wearable artificial kidney spent peritoneal dialysis solution circulation treatment system comprising one or more inlets connected with means for providing inflow and outflow into a patient's abdominal cavity, draining a volume of spent peritoneal dialysis solution from the patient's abdominal cavity, and storing the spent peritoneal dialysis solution. Because the patient's peritoneal cavity can withstand low pressures, the spent peritoneal dialysis solution pressure in the storage device is within about 30kpa, and pressures below 30kpa are difficult to pass through the filtration device if the spent dialysis solution is to be effectively filtered. Even if the minimum pressure requirement of the filtering device can meet below 30kpa, the filtering efficiency is greatly reduced. To improve the efficiency of toxin removal, the spent peritoneal dialysis solution needs to be pressurized. Under the action of the pressure difference, a part of the pressurized waste peritoneal dialysis solution passes through the filtering device to realize the removal of toxins.

In order to extend the useful life of the filtration device, it is necessary to drain the spent peritoneal dialysis concentrate that has not been completely filtered. For wearable artificial kidney devices based on peritoneal dialysis, the consequence of discarding the spent peritoneal dialysis solution is that the patient needs to carry more dialysis solution. The invention reduces the pressure of the high-pressure waste peritoneal dialysis concentrated solution through a loop with a pressure reducing valve, and then the high-pressure waste peritoneal dialysis concentrated solution flows into a waste peritoneal dialysis solution storage device for circular treatment. Not only improves the cleaning efficiency of the filtering device, but also reduces the abandonment of the waste peritoneal dialysis solution.

In everyday life, patients take in a certain amount of water by various means, which results in a larger amount of waste peritoneal dialysis solution being drained from the patient than fresh peritoneal membrane being infused. According to the wearable artificial kidney waste peritoneal dialysis solution circulation treatment system, when the waste peritoneal dialysis solution is judged to be more than the injected fresh dialysis solution by a certain amount, the fluid channel 7 in the circulation treatment loop controlled by the electromagnetic valve or other on-off control device 6 is opened, a certain amount of waste peritoneal dialysis concentrated solution is discharged and discharged, and the service life of the filtering device is further prolonged.

The invention is further described below with reference to the accompanying drawings.

A preferred embodiment of the present invention is shown in fig. 1.

A wearable artificial kidney spent peritoneal dialysis solution circulation treatment system includes an inlet 5 for providing inflow into the abdominal cavity of a patient and an outflow inlet 1, drains a volume of spent peritoneal dialysis solution from the abdominal cavity of the patient, and stores the spent peritoneal dialysis solution in a storage bag 2. Because the patient's peritoneal cavity can withstand low pressures, the spent peritoneal dialysis solution within the storage bag is at a pressure of approximately 30kpa, and pressures below 30kpa are difficult to pass through the filtration device 4 if the spent dialysis solution is to be effectively filtered. Even if the minimum of the filter device 4 can meet the pressure requirement below 30kpa, the efficiency of the filtration is greatly reduced. In order to improve the toxin removal efficiency, the waste peritoneal dialysis solution is pressurized by a pressurizing pump 3. Under the action of the pressure difference, a part of the pressurized waste peritoneal dialysis solution passes through the filtering device 4 to realize the removal of toxins.

In order to extend the useful life of the filtration device, it is necessary to drain the spent peritoneal dialysis concentrate that has not been completely filtered. For wearable artificial kidney devices based on peritoneal dialysis, the consequence of discarding the spent peritoneal dialysis solution is that the patient needs to carry more dialysis solution. The invention reduces the pressure of the high-pressure waste peritoneal dialysis concentrated solution through the loop with the pressure reducing valve 8, and then flows into the waste peritoneal dialysis solution storage device for circular treatment. Not only improves the cleaning efficiency of the filtering device, but also reduces the abandonment of the waste peritoneal dialysis solution.

In everyday life, patients take in a certain amount of water by various means, which results in a larger amount of waste peritoneal dialysis solution being drained from the patient than fresh peritoneal membrane being infused. According to the wearable artificial kidney waste peritoneal dialysis solution circulation treatment system, when the waste peritoneal dialysis solution is judged to be more than the injected fresh dialysis solution by a certain amount, the fluid channel 7 in the circulation treatment loop controlled by the electromagnetic valve or other on-off control device 6 is opened, a certain amount of waste peritoneal dialysis concentrated solution is discharged and discharged, and the service life of the filtering device is further prolonged.

Claims (3)

1. A wearable artificial kidney spent peritoneal dialysis solution circulation treatment system, characterized by comprising:

an inlet (1) for providing an inflow into the abdominal cavity of a patient and an outflow;

a waste peritoneal dialysis solution storage bag (2) for draining the waste peritoneal dialysis solution from the abdominal cavity of the patient and storing the waste peritoneal dialysis solution in the storage bag (2);

at least one closed loop fluid circuit carrying spent peritoneal dialysis solution from a source that has not been completely filtered;

at least one pump (3) connected in a closed-loop fluid circuit for pressurizing the spent peritoneal dialysis solution and delivering the pressurized spent peritoneal dialysis solution to a filtration system (4);

a filtration system (4) connected in a fluid system loop, the filtration system (4) removing at least one toxin from the spent peritoneal dialysis solution;

at least one pressure relief valve (8) connected in the closed-loop fluid circuit, the pressure relief valve (8) being adapted to depressurize spent dialysate that has passed through the filtration system but has not yet been completely filtered and to flow the depressurized spent peritoneal dialysis solution to a spent peritoneal dialysis solution storage device.

2. The wearable artificial kidney peritoneal dialysis solution circulation processing system of claim 1, characterized in that: the filtration process separates the spent peritoneal dialysis solution into a spent peritoneal dialysis concentrate and a filtered fluid.

3. The wearable artificial kidney peritoneal dialysis solution circulation processing system of claim 1, characterized in that: the closed loop fluid circuit comprises at least one bifurcated fluid passage (7), the fluid passage (7) being used for discharging the spent peritoneal dialysis concentrate; the passage (7) is communicated and disconnected by an electromagnetic valve or other devices (6) for controlling the on-off state.

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