CN115698270A - 一种通过iPS细胞生产再生T细胞的方法 - Google Patents
一种通过iPS细胞生产再生T细胞的方法 Download PDFInfo
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- CN115698270A CN115698270A CN202180038576.5A CN202180038576A CN115698270A CN 115698270 A CN115698270 A CN 115698270A CN 202180038576 A CN202180038576 A CN 202180038576A CN 115698270 A CN115698270 A CN 115698270A
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- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
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- A61K40/41—Vertebrate antigens
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- A61K40/4201—Neoantigens
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- A61K40/42—Cancer antigens
- A61K40/4242—Transcription factors, e.g. SOX or c-MYC
- A61K40/4243—Wilms tumor 1 [WT1]
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- A61K40/41—Vertebrate antigens
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/46—Viral antigens
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C12N15/09—Recombinant DNA-technology
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18811—Sendai virus
- C12N2760/18841—Use of virus, viral particle or viral elements as a vector
- C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
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- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020156848 | 2020-09-18 | ||
| JP2020-156848 | 2020-09-18 | ||
| JP2021070531 | 2021-04-19 | ||
| JP2021-070531 | 2021-04-19 | ||
| PCT/JP2021/034333 WO2022059780A1 (ja) | 2020-09-18 | 2021-09-17 | iPS細胞を介する再生T細胞の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115698270A true CN115698270A (zh) | 2023-02-03 |
Family
ID=80776150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180038576.5A Pending CN115698270A (zh) | 2020-09-18 | 2021-09-17 | 一种通过iPS细胞生产再生T细胞的方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230183645A1 (https=) |
| EP (1) | EP4215604A4 (https=) |
| JP (1) | JPWO2022059780A1 (https=) |
| CN (1) | CN115698270A (https=) |
| WO (1) | WO2022059780A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021000459A (es) * | 2018-07-13 | 2021-06-23 | Univ Kyoto | Metodo para producir celulas t gamma y delta. |
| JPWO2022220146A1 (https=) * | 2021-04-16 | 2022-10-20 | ||
| JPWO2023249071A1 (https=) * | 2022-06-24 | 2023-12-28 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2011096482A1 (ja) | 2010-02-03 | 2013-06-13 | 国立大学法人 東京大学 | 多能性幹細胞を用いた免疫機能再建法 |
| EP2639297B1 (en) * | 2010-11-09 | 2018-01-03 | National Institute of Advanced Industrial Science And Technology | Method for producing peripheral blood monocyte-derived pluripotent stem cells |
| EP2853590B1 (en) * | 2012-05-22 | 2018-11-07 | The University of Tokyo | Method for producing antigen-specific t cells |
| KR102654784B1 (ko) * | 2014-07-18 | 2024-04-04 | 사이아스 가부시키가이샤 | 다능성 줄기세포로부터 세포-기반 면역요법용 t 세포를 유도하는 방법 |
| EP3170896B1 (en) * | 2014-07-18 | 2020-03-11 | Kawamoto, Hiroshi | Production method for pluripotent stem cells having antigen-specific t cell receptor gene |
| WO2016145578A1 (en) * | 2015-03-13 | 2016-09-22 | Syz Cell Therapy Co. | Methods of cancer treatment using activated t cells |
| TW201835100A (zh) * | 2017-02-06 | 2018-10-01 | 國立研究開發法人國立癌症研究中心 | 新穎t細胞受體 |
| JP7763588B2 (ja) * | 2017-09-05 | 2025-11-04 | グリットストーン バイオ インコーポレイテッド | T細胞療法用の新生抗原の特定法 |
| CN112752838A (zh) * | 2018-07-26 | 2021-05-04 | 国立大学法人京都大学 | 制备引入外源抗原受体的细胞的方法 |
| EP3831936A4 (en) * | 2018-07-31 | 2022-04-13 | Thyas Co. Ltd. | METHOD FOR PRODUCING A REGENERATED T LYMPHOCYTE POPULATION USING IPS CELLS |
| AU2020393334A1 (en) * | 2019-11-25 | 2022-06-16 | Kyoto University | T-cell master cell bank |
| JPWO2022145490A1 (https=) * | 2021-01-04 | 2022-07-07 | ||
| JPWO2022220146A1 (https=) * | 2021-04-16 | 2022-10-20 |
-
2021
- 2021-09-17 WO PCT/JP2021/034333 patent/WO2022059780A1/ja not_active Ceased
- 2021-09-17 EP EP21869462.8A patent/EP4215604A4/en active Pending
- 2021-09-17 JP JP2022550632A patent/JPWO2022059780A1/ja active Pending
- 2021-09-17 US US17/924,480 patent/US20230183645A1/en active Pending
- 2021-09-17 CN CN202180038576.5A patent/CN115698270A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2022059780A1 (https=) | 2022-03-24 |
| EP4215604A4 (en) | 2025-01-01 |
| EP4215604A1 (en) | 2023-07-26 |
| US20230183645A1 (en) | 2023-06-15 |
| WO2022059780A1 (ja) | 2022-03-24 |
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