CN115651823A - Bone marrow cell morphology analysis system - Google Patents
Bone marrow cell morphology analysis system Download PDFInfo
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- CN115651823A CN115651823A CN202211179943.6A CN202211179943A CN115651823A CN 115651823 A CN115651823 A CN 115651823A CN 202211179943 A CN202211179943 A CN 202211179943A CN 115651823 A CN115651823 A CN 115651823A
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Abstract
The bone marrow cell morphology analysis system provided by the invention comprises a base, wherein a loading module and a detection module are arranged on the base at one side of the loading module, the loading module comprises a slide rack and a slide conveying mechanism, the detection module comprises a microscope and a slide placing platform, the slide conveying mechanism can automatically convey a slide from the slide rack to the slide placing platform positioned below the microscope, after a sample on the slide is detected by the microscope, the slide conveying mechanism can automatically return the slide to the slide rack, and the whole process can realize complete automatic operation, so that the sample detection efficiency is greatly improved, and meanwhile, the mechanical operation is utilized, and the accuracy of each detection result is favorably ensured.
Description
Technical Field
The invention relates to the field of medical detection, in particular to a bone marrow cell morphology analysis system.
Background
Myelomorphic microscopy is one of the key diagnostic tools in hematology and is commonly used to diagnose a variety of conditions including leukemia, multiple myeloma, lymphoma, anemia, and pancytopenia. According to the guideline for diagnosing malignant tumors of bone marrow issued by the world health organization, detailed and accurate manual microscopic examination is required in diagnosis. Normal bone marrow contains all differentiated cells at developmental stages, from early precursor stem cells to functionally mature cells, including hematopoietic stem cells, which are the precursors of most blood cells, as well as mesenchymal and endothelial stem cells, which are considered the gatekeeper cells of the bone marrow. The morphological characteristics of these cells depend on their own biological characteristics and are affected by the process of smear, staining and image acquisition.
The quality inspection of the quality of the bone marrow cell smear and the acquisition and analysis of image information are very critical, and the accuracy of the later analysis result is directly determined. However, with the increase of the current detection amount, the manual detection mode can not meet the requirements of people in efficiency, and meanwhile, heavy work can cause physical and mental fatigue of detection personnel, so that the phenomenon of inaccurate detection results can be caused.
Disclosure of Invention
Aiming at the problems in the prior art, the bone marrow cell morphology analysis system provided by the invention can well solve the problems in the background technology.
In order to achieve the purpose, the invention adopts the following technical scheme:
the bone marrow cell morphological analysis system comprises a base, wherein a feeding module and a detection module are arranged on the base at one side of the feeding module,
the loading module comprises a slide rack and a slide conveying mechanism, the slide conveying mechanism is used for conveying the slides on the slide rack to the detection module, and the slide conveying mechanism can convey a plurality of slides at one time,
the slide conveying mechanism is used for conveying the slide which is positioned on the detection module and is detected to the other slide rack in the loading module;
the detection module comprises a microscope, a scanner and a slide placing platform, the slide conveying mechanism conveys the slide to the slide placing platform, the slide placing platform drives the slide above the slide to be below a lens of the microscope, the microscope is used for detecting a sample on the slide, and the scanner is used for scanning two-dimensional code information on the slide.
In one embodiment, the slide conveying mechanism comprises a conveying support, the conveying support is arranged on the base, a conveying bottom plate is arranged on the conveying support, a first slide rail is arranged on the conveying bottom plate, a first slide block is arranged on the first slide rail, a transmission plate is arranged on the first slide block, a first motor is arranged on the conveying bottom plate at one end of the first slide rail, a first toothed belt wheel is rotatably arranged on the conveying bottom plate at the other end of the first slide rail, a second toothed belt wheel is arranged on a main shaft of the first motor, a first toothed belt is sleeved on the first toothed belt wheel and the second toothed belt wheel,
the transmission plate is provided with a first connecting block, the first connecting block is provided with a first toothed block, the first toothed block and the first toothed belt are meshed with each other,
the slide rack is characterized in that a connecting rod is arranged on the transmission plate, a driving plate used for driving the slide is arranged on the connecting rod, the driving plate is located below the slide rack, and the detection module is located on a base at one end of the first slide rail.
In one embodiment, a driving plate lifting hole is formed in the conveying bottom plate, the first sliding rails are symmetrically arranged on two sides of the driving plate lifting hole respectively, a motor bottom plate is arranged below the driving plate, a second motor is arranged on the motor bottom plate, the lower end of the connecting rod sequentially penetrates through the driving plate and the driving plate lifting hole to be connected with the motor bottom plate, and a spindle of the second motor penetrates through the driving plate and is in threaded connection with the driving plate.
In one embodiment, the slide rack comprises two base plates and two base plates, the two base plates are arranged above the conveying support in the front-back direction, the base plates are arranged in parallel with the first sliding rail, the two base plates are respectively provided with a plurality of column plates at intervals, a space for containing a slide is formed between every two adjacent column plates on the two base plates, the cross section of each column plate at the end of each base plate is in an L shape, and the cross section of each column plate at the middle of each base plate is in an inverted T shape or a '\ 9522'.
In one embodiment, three upright column plates are symmetrically arranged on two base plates respectively, a slide plate is stacked between four adjacent upright column plates at the left end of the two base plates, a plurality of slides to be detected are placed on the slide plate, slide stop pins capable of moving up and down are arranged on the inner sides of the two upright column plates in the middle of the base plates respectively, and the two slide stop pins are arranged below the slides to be detected respectively,
the lower ends of the side walls positioned at the inner sides on the upright post plates are respectively provided with a first gap, a channel for sliding the slide is formed between the lower ends of the side walls positioned at the inner sides on the upright post plates and the upper end surface of the base plate,
the upper surface of the driving plate is provided with a slide plate driving block, the lower surface of the slide plate is provided with a driving hole, and the slide plate driving block can be correspondingly inserted into the driving hole so as to drive the slide plate loaded with the slide to be detected to move leftwards until the slide plate falls into a channel formed between the column plate and the base plate.
In one embodiment, a slide plate is also placed between four upright column plates adjacent to the right end on the two base plates, and a slide plate is placed between four upright column plates adjacent to the right end on the two base plates and is used for placing a slide detected by the detection module.
In one of them embodiment, two be provided with the spacing block seat of slide board on the bed plate respectively, the spacing block seat of slide board is located respectively between two stand boards of bed plate right-hand member, it can be relative to be provided with respectively on the spacing block seat of slide board deflect around the bed plate and the slide board stopper of self return, the inside wall of slide board stopper from top to bottom gradually to the inboard setting of bed plate slope, and two distance between the slide board stopper top is less than the length of slide board fore-and-aft direction, distance between the bottom are greater than the length of slide board fore-and-aft direction, are used for placing the process the slide board pile of slide after the detection module detects is two on the slide board stopper.
In one embodiment, a microscope support is arranged on the base on the right side of the base plate, the microscope and the scanner are arranged on the microscope support, the slide placing platform is arranged below the microscope support, and the scanner is arranged at the left end of the microscope support.
In one embodiment, the slide placement platform comprises a platform base, a first moving plate, a second moving plate, and a slide plate retaining plate,
the platform base is arranged on the base, a second slide rail along the front-back direction is arranged on the platform base, a second slide block is arranged on the second slide rail,
the first moving plate is arranged on the second sliding block, a first linear motor for driving the first moving plate is arranged between the platform base and the first moving plate,
the first moving plate is provided with a third slide rail along the left-right direction, the third slide rail is provided with a third slide block,
the second moving plate is arranged on the third sliding block, a second linear motor for driving the second moving plate is arranged between the second moving plate and the first moving plate,
the slide plate fixing plate is disposed on the second moving plate.
In one embodiment, a second notch is formed in one side, close to the slide rack, of the slide plate fixing plate, sunken steps are respectively arranged at each edge of the second notch, a slide plate fixing elastic sheet is further arranged on the slide plate fixing plate, one end of the slide plate fixing elastic sheet is connected with the upper surface of the slide plate fixing plate, the other end of the slide plate fixing elastic sheet is located above the steps of the slide plate fixing plate, and the slide plate driving block drives the slide plate to pass through a channel formed between the upright post plate and the base plate until the slide plate passes through the steps of the slide plate fixing plate and is fixed through the slide plate fixing elastic sheet.
Compared with the prior art, the bone marrow cell morphology analysis system provided by the invention comprises a base, wherein a loading module and a detection module are arranged on the base at one side of the loading module, the loading module comprises a slide rack and a slide conveying mechanism, the detection module comprises a microscope and a slide placing platform, the slide can be automatically conveyed from the slide rack to the slide placing platform positioned below the microscope through the slide conveying mechanism, after a sample on the slide is detected through the microscope, the slide conveying mechanism can automatically send the slide back to the slide rack, and the whole process can realize complete automatic operation, so that the sample detection efficiency is greatly improved, and meanwhile, the mechanical operation is utilized, and the accuracy of each detection result is favorably ensured.
Drawings
FIG. 1 is a first perspective view of the present invention;
FIG. 2 is a second partial perspective view of the present invention;
FIG. 3 is a third partial perspective view of the present invention;
FIG. 4 is a schematic bottom view of the slide plate of the present invention;
FIG. 5 is a fourth partial perspective view of the present invention;
FIG. 6 is a schematic perspective view of a fifth embodiment of the present invention;
FIG. 7 is a schematic perspective view of the slide plate stopper and the slide plate stopper shaft according to the present invention
Fig. 8 is a perspective view of the slide placing table in the present invention.
Detailed Description
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "axial," "radial," and the like are used in the indicated orientations and positional relationships based on the orientation shown in the drawings for convenience in describing the invention and simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus are not to be considered as limiting.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless expressly stated or limited otherwise, the first feature "on" or "under" the second feature may be directly contacting the second feature or the first and second features may be indirectly contacting each other through intervening media. Also, a first feature "on," "above," and "over" a second feature may be directly on or obliquely above the second feature, or simply mean that the first feature is at a higher level than the second feature. A first feature "under," "beneath," and "under" a second feature may be directly under or obliquely under the second feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
As shown in the figures 1-8 of the drawings,
the bone marrow cell morphology analysis system comprises a base 1, a feeding module 100 and a detection module 200 arranged on the base at the right side of the feeding module 100 are arranged on the base 1,
the loading module 100 includes a slide rack 300 and a slide transport mechanism 400, the slide transport mechanism 400 being used to transport slides 2 on the slide rack 300 to the detection module 200, and the slide transport mechanism 400 being capable of transporting several slides 2 at a time,
and a slide transfer mechanism 400 for transferring the slide 2, which is located on the inspection module 200 and has been inspected, to another slide rack 300 in the loading module 100;
the detection module 200 comprises a microscope 3, a scanner 4 and a slide placing platform 500, the slide conveying mechanism 400 conveys a slide 2 to the slide placing platform 500, the slide placing platform 500 drives the slide 2 positioned above the slide placing platform to the lower part of a lens of the microscope 3, the microscope 3 is used for detecting a sample on the slide 2, the scanner 4 is used for scanning two-dimensional code information on the slide 2, the two-dimensional code information contains identity information of patient personnel corresponding to the detected sample, so that the detection information is completely matched with the patient personnel, and meanwhile, the presentation and printing of a subsequent detection result are facilitated.
In this embodiment, the slide conveying mechanism 400 includes a conveying support 5, the conveying support 5 is disposed on the base 1, a conveying bottom plate 6 is disposed on the conveying support 5, a first slide rail 7 is disposed on the conveying bottom plate 6, a first slide block 8 is disposed on the first slide rail 7, a transmission plate 9 is disposed on the first slide block 8, a first motor 10 is disposed on the conveying bottom plate 6 at one end of the first slide rail 7, a first toothed belt wheel 11 is rotatably disposed on the conveying bottom plate 6 at the other end of the first slide rail 7 via a rotation shaft, a second toothed belt wheel 12 is disposed on a main shaft of the first motor 10, a first toothed belt 13 is sleeved on the first toothed belt wheel 11 and the second toothed belt wheel 12,
the transmission plate 9 is provided with a first connecting block 14, the first connecting block 14 is provided with a first toothed block 15, the first connecting block 14 and the first toothed block 15 are mutually attached to clamp the first toothed belt 13 between the first connecting block 14 and the first toothed block 15, meanwhile, the first toothed block 15 and the first toothed belt 13 are mutually meshed through the teeth on the first toothed belt 13,
a connecting rod 16 is arranged on the driving plate 9, a driving plate 17 for driving the slide 2 is arranged on the connecting rod 16, the driving plate 17 is positioned below the slide rack 300, and the detection module 200 is positioned on the base 1 at the right end of the first slide rail 7;
through the structural design, the following effects can be obtained: the first motor 10 drives the driving plate 17 to move left and right along the first slide rail 7 through the first toothed belt 13, the first toothed block 15, the first connecting block 14, the driving plate 9 and the connecting rod 16, and further the purpose of driving the slide on the slide rack 300 to the detection module 200 is achieved;
furthermore, a driving plate lifting hole is formed in the conveying bottom plate 6, first sliding rails 7 are symmetrically arranged on two sides of the driving plate lifting hole respectively, and through the arrangement of the two first sliding rails 7, the driving plate 9 can move more stably, the corresponding driving plate 17 can move more stably and accurately, and therefore accurate conveying operation of the slide 2 is achieved; a motor bottom plate 19 is arranged below the transmission plate 9, a second motor 20 is arranged on the motor bottom plate 19, the lower end of the connecting rod 16 sequentially penetrates through the transmission plate 19 and the driving plate lifting hole to be connected with the motor bottom plate 19, and a main shaft of the second motor 20 upwards penetrates through the transmission plate 19 and is in threaded connection with the transmission plate 19;
preferably, a first shaft sleeve 44 is arranged at the central point of the driving plate 9, two second shaft sleeves 45 are symmetrically arranged on the driving plate 9 relative to the central point of the driving plate, connecting rods 16 are slidably arranged in the two second shaft sleeves 45 respectively, a main shaft of the second motor 20 is in threaded connection with the first shaft sleeve 44, and the two connecting rods 16 are symmetrically arranged to drive the driving plate 17 to move up and down, so that the up-and-down movement process of the driving plate 17 is more stable, and the stable up-and-down movement of the slide 2 is further realized;
through the structural design, the following effects can be obtained: when the main shaft of the second motor 20 rotates, since the driving plate 19 is fixed on the conveying base plate 6, the conveying base plate 6 is fixed on the base 1 through the conveying bracket 5, and thus the second motor 20, the motor base plate 19, the connecting rod 16, and the driving plate 17 can be moved up or down together.
In this embodiment, the slide rack 300 includes two base plates 22 and upright plates 21, the two base plates 22 are disposed above the conveying frame 5 in a front-back direction and parallel to each other, the base plates 22 are disposed parallel to the first slide rail 7, the two base plates 22 are respectively provided with a plurality of upright plates 21 at intervals, and are disposed on the two base plates 22, and a space for accommodating the slide 2 is formed between the adjacent four upright plates 21, the cross section of the upright plate 21 at the end of the base plate 22 is "L" shaped, and the cross section of the upright plate 21 at the middle of the base plate 22 is "inverted" shaped or "2295;";
specifically, three upright column plates 21 are symmetrically arranged on two base plates 22 respectively, a plurality of slide plates 23 are stacked between four adjacent upright column plates 21 and positioned at the left ends of the two base plates 22, five slides 2 to be detected are respectively placed on each slide plate 23, slide stop pins 24 capable of moving up and down are respectively arranged on the inner sides of the two upright column plates 21 positioned in the middle of the base plates 22, the two slide stop pins 24 are respectively positioned below the slides 2 to be detected,
the lower ends of the side walls at the inner side of the column plate 21 are respectively provided with a first notch 25, a channel for sliding the slide is formed between the lower end of the side wall at the inner side of the column plate 21 and the upper end surface of the base plate 22,
the upper surface of the driving plate 17 is provided with a slide plate driving block 26, the lower surface of the slide plate 23 is provided with a driving hole 27, the slide plate driving block 26 can be correspondingly inserted into the driving hole 27,
specifically, the column plate 21 is respectively provided with a stop pin hole 46, the slide stop pin 24 is slidably embedded in the stop pin hole 46, the height of the stop pin hole 46 is greater than that of the slide stop pin 24, the inner side of the slide stop pin 24 protrudes inwards to exceed the inner side wall of the column plate 21 and is positioned below the slide 2,
a stop pin adjusting block 47 is respectively arranged on the upright column plate 21 above the stop pin holes 46, a stop pin adjusting screw 48 is screwed on the stop pin adjusting block 47, and the threaded end of the stop pin adjusting screw 48 penetrates through the stop pin adjusting block 47 to be screwed with the slide stop pin 24, so that the slide stop pin 24 can be driven to move up and down in the stop pin holes 46 by rotating the stop pin adjusting screw 48, and the height of the right end of the slide 2 is adjusted;
therefore, firstly, the second motor 20 drives the slide plate driving block 26 to move downwards through the driving plate 17, then the first motor 10 drives the slide plate driving block 26 through the driving plate 17 to come under the driving hole 27 at the bottom of the slide plate 23, then the second motor drives the slide plate driving block 26 to insert upwards into the driving hole 27, then the first motor 10 drives the slide plate 23 loaded with the slide 2 to be detected to move leftwards, after moving for a certain distance, the right end of the slide plate 23 falls off the two slide stop pins 24 until the whole slide plate 23 falls into the channel formed between the column plate 21 and the base plate 22, and then the first motor 10 continues to drive the slide plate 23 loaded with the slide 2 to be detected to move rightwards until the slide plate 23 is conveyed to the slide placing platform 500.
In this embodiment, the slide plate 23 is also disposed between the four column plates 21 adjacent to the right end of the two base plates 22, and the slide plate 23 disposed between the four column plates 21 adjacent to the right end of the two base plates 22 is used for placing the slide detected by the detection module 200;
furthermore, two base plates 22 are respectively provided with a slide plate limiting block seat 28, the slide plate limiting block seats 28 are respectively positioned between the two upright column plates 21 at the right end of the base plates 22, the slide plate limiting block seats 28 are respectively provided with a slide plate limiting block 29 which can deflect back and forth relative to the base plates 22 and can automatically return,
preferably, the slide plate limiting block seats 28 are respectively embedded with slide plate limiting block rotating shafts 49, two ends of the slide plate limiting block rotating shafts 49 respectively penetrate through the side walls of the slide plate limiting block seats 28, return springs are arranged between the slide plate limiting block rotating shafts 49 and the slide plate limiting block seats 28 and sleeved on the slide plate limiting block rotating shafts 49, two ends of the slide plate limiting block rotating shafts 49 are respectively provided with slide plate limiting blocks 29 for placing the slide plates 23 of the detected slides 2 to be stacked on the four slide plate limiting blocks 29,
further, the inner side walls of the slide plate limiting blocks 29 are arranged to be inclined towards the inner side of the base plate 22 gradually from top to bottom, the distance between the tops of the two slide plate limiting blocks 29 is smaller than the length of the slide plate 23 in the front-back direction, the distance between the bottoms of the two slide plate limiting blocks is larger than the length of the slide plate 23 in the front-back direction,
after the slide 2 on the slide platform 500 is detected, the first motor 10 drives the slide plate 23 loaded with the slide 2 on the slide platform 500 to the lower side of the four slide plate stoppers 29 through the slide plate driving block 26, and then drives the whole slide plate 23 to move upwards through the second motor 20, because the inner side wall of the slide plate stopper 29 is inclined from top to bottom gradually towards the inner side of the base plate 22, and meanwhile, the slide plate can deflect back and forth relative to the base plate 22 and can automatically return,
therefore, in the process of moving the slide plate 23 upward, the upper end of the slide plate stopper 29 deflects outward slowly to allow the slide plate 23 to move upward until the bottom of the slide plate 23 exceeds the top end of the slide plate stopper 29, at this time, the slide plate stopper 29 deflects inward automatically under the action of the return spring, and meanwhile, because the distance between the tops of the slide plate stoppers 29 on the front side and the rear side after return is smaller than the length of the slide plate 23 in the front-rear direction, after the second motor 20 drives the slide plate driving block 26 to withdraw from the driving hole 27 on the slide plate 23, the slide plate 23 is erected on the four slide plate stoppers 29, so that the above actions are repeated, and meanwhile, a plurality of slide plates 23 are stacked between the four upright column plates 21 adjacent to the right end on the two base plates 22, so as to achieve the recovery of the slide 2 after detection.
In the present embodiment, an arch-like microscope stand 30 is provided on the base 1 on the right side of the base plate 22, a microscope 3 and a scanner 4 are provided on the microscope stand 30, a slide placing platform 500 is provided below the microscope stand 20, and the scanner 4 is provided at the left end of the microscope stand 30.
In the present embodiment, the slide placing platform 500 includes a platform base 31, a first moving plate 32, a second moving plate 33, and a slide plate fixing plate 34,
the platform base 31 is arranged on the base 1, two second slide rails 35 which are parallel to each other and are arranged along the front-back direction are arranged on the platform base 31, a second slide block is arranged on the second slide rails 35,
the first moving plate 32 is provided on the second slider, a first linear motor for driving the first moving plate 32 is provided between the platform base 31 and the first moving plate 32,
the first moving plate 32 is provided with two third sliding rails 38 which are parallel to each other and are arranged along the left-right direction, the third sliding rails 38 are provided with third sliding blocks,
the second moving plate 33 is provided on the third slider, a second linear motor for driving the second moving plate 33 is provided between the second moving plate 33 and the first moving plate 32,
the slide plate fixing plate 34 is provided on the second moving plate 33;
through the structural design, the following characteristics can be obtained: the slide plate holding plate 34 for holding the slide plate 23 from the slide rack 300 can be moved back and forth and left and right relative to the microscope 3 by the first linear motor and the second linear motor until the slide 2 on the slide plate 23 is moved to the proper position for the microscope 3 to examine the specimen above it.
In this embodiment, a second notch is formed in a side of the slide plate fixing plate 34 close to the slide rack 300, each edge of the second notch is provided with a sunken step 42, slide plate fixing elastic pieces 43 are further disposed on front and rear ends of the slide plate fixing plate 34, one end of each slide plate fixing elastic piece 43 is connected to the upper surface of the slide plate fixing plate 34, and the other end of each slide plate fixing elastic piece 43 is located above the corresponding step 42 on the front and rear ends of the slide plate fixing plate 34, so that the slide plate driving block 26 drives the slide plate 23 from the slide rack 300 to pass through a channel formed between the column plate 21 and the base plate 22 to the step 43 of the slide plate fixing plate 34 and is fixed by the slide plate fixing elastic pieces 43, and meanwhile, because the scanner 4 is located at the left end of the microscope stand 30, the scanner 4 scans two-dimensional code information on each slide plate 2 on the slide plate 23 first and transmits the information to a controller for controlling the operation of the whole apparatus, and meanwhile, the controller transmits information obtained by detecting the information of the slide 2 and the microscope sample to form a complete report.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is specific and detailed, but not to be understood as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent should be subject to the appended claims.
Claims (10)
1. The bone marrow cell morphological analysis system is characterized by comprising a base, wherein a feeding module and a detection module are arranged on the base at one side of the feeding module,
the loading module comprises a slide rack and a slide conveying mechanism, the slide conveying mechanism is used for conveying the slides on the slide rack to the detection module, and the slide conveying mechanism can convey a plurality of slides at one time,
the slide conveying mechanism is used for conveying the slide which is positioned on the detection module and is detected to the other slide rack in the loading module;
the detection module comprises a microscope, a scanner and a slide placing platform, the slide conveying mechanism conveys the slide to the slide placing platform, the slide placing platform drives the slide above the slide to be below a lens of the microscope, the microscope is used for detecting a sample on the slide, and the scanner is used for scanning two-dimensional code information on the slide.
2. The bone marrow cell morphology analysis system according to claim 1, wherein the slide conveying mechanism comprises a conveying support, the conveying support is disposed on the base, a conveying bottom plate is disposed on the conveying support, a first slide rail is disposed on the conveying bottom plate, a first slide block is disposed on the first slide rail, a transmission plate is disposed on the first slide block, a first motor is disposed on the conveying bottom plate at one end of the first slide rail, a first toothed belt wheel is rotatably disposed on the conveying bottom plate at the other end of the first slide rail, a second toothed belt wheel is disposed on a main shaft of the first motor, and a first toothed belt is sleeved on the first toothed belt wheel and the second toothed belt wheel,
the transmission plate is provided with a first connecting block, the first connecting block is provided with a first toothed block, the first toothed block and the first toothed belt are meshed with each other,
the slide rack is characterized in that a connecting rod is arranged on the transmission plate, a driving plate used for driving the slide is arranged on the connecting rod, the driving plate is located below the slide rack, and the detection module is located on a base at one end of the first slide rail.
3. The bone marrow cell morphology analysis system according to claim 2, characterized in that a driving plate lifting hole is arranged on the conveying bottom plate, the first slide rails are symmetrically arranged on two sides of the driving plate lifting hole respectively, a motor bottom plate is arranged below the driving plate, a second motor is arranged on the motor bottom plate, the lower end of the connecting rod sequentially penetrates through the driving plate and the driving plate lifting hole to be connected with the motor bottom plate, and a main shaft of the second motor penetrates through the driving plate and is in threaded connection with the driving plate.
4. The bone marrow cell morphology analysis system according to claim 3, wherein the slide holder comprises a plurality of pillar plates and two base plates, the two base plates are arranged above the conveying support in a front-back direction and are parallel to the first slide rail, the plurality of pillar plates are arranged on the two base plates at intervals, a space for accommodating a slide is formed between the adjacent four pillar plates on the two base plates, the cross section of the pillar plate at the end of the base plate is L-shaped, and the cross section of the pillar plate at the middle of the base plate is T-shaped or 9522.
5. The bone marrow cytomorphology analysis system according to claim 4, characterized in that three column plates are symmetrically arranged on two base plates respectively, a slide plate is stacked between four adjacent column plates at the left end of the two base plates, a plurality of slides to be detected are placed on the slide plate, slide stop pins capable of moving up and down are respectively arranged on the inner sides of the two column plates at the middle part of the base plates, and the two slide stop pins are respectively arranged below the slides to be detected,
the lower ends of the side walls positioned on the inner side of the upright post plate are respectively provided with a first notch, a channel for sliding the slide is formed between the lower end of the side wall positioned on the inner side of the upright post plate and the upper end surface of the base plate,
the upper surface of the driving plate is provided with a slide plate driving block, the lower surface of the slide plate is provided with a driving hole, and the slide plate driving block can be correspondingly inserted into the driving hole so as to drive the slide plate loaded with the slide to be detected to move leftwards until the slide plate falls into a channel formed between the column plate and the base plate.
6. The bone marrow cytomorphology analysis system according to claim 5, characterized in that, a slide plate is also placed between the four column plates adjacent to the right end of the two base plates, and a slide plate is placed between the four column plates adjacent to the right end of the two base plates for placing the slide after being detected by the detection module.
7. The bone marrow cell morphology analysis system of claim 6, characterized in that two slide plate limiting block seats are respectively arranged on the two base plates, the slide plate limiting block seats are respectively positioned between the two upright plates at the right end of the base plates, slide plate limiting blocks capable of deflecting and automatically returning relative to the base plates are respectively arranged on the slide plate limiting block seats, the inner side walls of the slide plate limiting blocks are gradually inclined towards the inner sides of the base plates from top to bottom, and the distance between the tops of the two slide plate limiting blocks is smaller than the length of the front and back direction of the slide plates, and the distance between the bottoms of the two slide plate limiting blocks is larger than the length of the front and back direction of the slide plates, so that the slide plates of slides detected by the detection module are stacked on the two slide plate limiting blocks.
8. The bone marrow cell morphology analysis system according to claim 5, characterized in that a microscope stand is arranged on the pedestal on the right side of said base plate, said microscope and said scanner are arranged on said microscope stand, said slide placing platform is arranged under said microscope stand, and said scanner is arranged at the left end of said microscope stand.
9. The bone marrow cell morphology analysis system of claim 8, wherein the slide placement platform comprises a platform base, a first moving plate, a second moving plate, and a slide plate securing plate,
the platform base is arranged on the base, a second slide rail along the front-back direction is arranged on the platform base, a second slide block is arranged on the second slide rail,
the first moving plate is arranged on the second sliding block, a first linear motor for driving the first moving plate is arranged between the platform base and the first moving plate,
the first moving plate is provided with a third slide rail along the left-right direction, the third slide rail is provided with a third slide block,
the second moving plate is arranged on the third sliding block, a second linear motor for driving the second moving plate is arranged between the second moving plate and the first moving plate,
the slide plate fixing plate is disposed on the second moving plate.
10. The bone marrow cell morphology analysis system of claim 9, wherein a second notch is provided on a side of the slide plate fixing plate close to the slide rack, each edge of the second notch is provided with a sunken step, a slide plate fixing elastic sheet is further provided on the slide plate fixing plate, one end of the slide plate fixing elastic sheet is connected with the upper surface of the slide plate fixing plate, the other end of the slide plate fixing elastic sheet is located above the steps on the slide plate fixing plate, and the slide plate driving block drives the slide plate to pass through a channel formed between the column plate and the base plate until the slide plate is on the steps of the slide plate fixing plate and fixed by the slide plate fixing elastic sheet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211179943.6A CN115651823A (en) | 2022-09-27 | 2022-09-27 | Bone marrow cell morphology analysis system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211179943.6A CN115651823A (en) | 2022-09-27 | 2022-09-27 | Bone marrow cell morphology analysis system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115651823A true CN115651823A (en) | 2023-01-31 |
Family
ID=84986478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211179943.6A Pending CN115651823A (en) | 2022-09-27 | 2022-09-27 | Bone marrow cell morphology analysis system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115651823A (en) |
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2022
- 2022-09-27 CN CN202211179943.6A patent/CN115651823A/en active Pending
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