CN115607601A - A Chinese medicinal composition for the treatment of colitis - Google Patents
A Chinese medicinal composition for the treatment of colitis Download PDFInfo
- Publication number
- CN115607601A CN115607601A CN202211386428.5A CN202211386428A CN115607601A CN 115607601 A CN115607601 A CN 115607601A CN 202211386428 A CN202211386428 A CN 202211386428A CN 115607601 A CN115607601 A CN 115607601A
- Authority
- CN
- China
- Prior art keywords
- traditional chinese
- chinese medicine
- herbal medicines
- chinese herbal
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating colitis, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating colitis is prepared from the following Chinese herbal medicines in parts by weight: 10-15g of coreopsis tinctoria, 5-8g of sweet wormwood, 1-2g of dried rehmannia root and 1-2g of radix sophorae flavescentis. The Chinese herbal medicine adopted in the composition has wide sources, and has the characteristics of low cost, high cure rate and quick response.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating colitis.
Background
Colitis is also called nonspecific ulcerative colitis, has slow onset of disease and inconsistent disease condition, and is mainly clinically manifested by diarrhea, abdominal pain, mucous stool, bloody purulent stool, tenesmus, even constipation, and inability to get stool within several days; frequent diarrhea and constipation often accompanied by emaciation and hypodynamia are often accompanied by recurrent attacks.
The traditional Chinese medicine for treating colitis at present has the problems of slow effect taking, low cure rate and the like, so the development of a traditional Chinese medicine for efficiently treating colitis is urgently needed.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide the traditional Chinese medicine composition for treating the colitis, which is prepared from four Chinese herbal medicines of coreopsis tinctoria, sweet wormwood herb, dried rehmannia root and lightyellow sophora root, and has the characteristics of low cost, quick drug effect and high cure rate.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine composition for treating colitis is composed of the following Chinese herbal medicines by weight:
10-15g of coreopsis tinctoria, 5-8g of sweet wormwood, 1-2g of dried rehmannia root and 1-2g of radix sophorae flavescentis.
In one embodiment, the traditional Chinese medicine composition for treating colitis is prepared from the following Chinese herbal medicines in parts by weight:
10g of coreopsis tinctoria, 5g of sweet wormwood, 1g of dried rehmannia root and 2g of radix sophorae flavescentis.
In one embodiment, the traditional Chinese medicine composition for treating colitis consists of the following Chinese herbal medicines by weight:
11g of coreopsis tinctoria, 5g of sweet wormwood, 2g of dried rehmannia root and 1g of radix sophorae flavescentis.
In one embodiment, the traditional Chinese medicine composition for treating colitis consists of the following Chinese herbal medicines by weight:
12g of coreopsis tinctoria, 8g of sweet wormwood, 1g of dried rehmannia root and 1g of radix sophorae flavescentis.
In one embodiment, the traditional Chinese medicine composition for treating colitis is prepared from the following Chinese herbal medicines in parts by weight:
13g of snow chrysanthemum, 7g of sweet wormwood herb, 2g of dried rehmannia root and 1g of lightyellow sophora root.
In one embodiment, the traditional Chinese medicine composition for treating colitis is prepared from the following Chinese herbal medicines in parts by weight:
14g of coreopsis tinctoria, 6g of sweet wormwood herb, 1g of dried rehmannia root and 2g of lightyellow sophora root.
In one embodiment, the traditional Chinese medicine composition for treating colitis consists of the following Chinese herbal medicines by weight:
15g of snow chrysanthemum, 5g of sweet wormwood herb, 1g of dried rehmannia root and 2g of lightyellow sophora root.
The invention also provides a traditional Chinese medicine preparation for treating colitis, which is prepared by processing the traditional Chinese medicine composition, and the preparation is in the form of decoction, tablets, powder or other medically acceptable preparations.
The invention also provides a preparation method of the traditional Chinese medicine preparation for treating colitis, which specifically comprises the following steps:
weighing the dried Chinese herbal medicines according to a proportion, mixing and crushing the Chinese herbal medicines, and then adding ethanol into the mixture for soaking treatment; heating reflux extraction is carried out for 1-2h after soaking; filtering, collecting the filter residue and filtrate, performing secondary alcohol extraction on the filter residue, and combining the filtrates; the combined filtrates were concentrated under reduced pressure and freeze-dried to obtain a solid powder.
In the invention, the soaking temperature is 25-45 ℃, and the soaking time is 8-24h.
In the method for preparing a Chinese medicinal preparation of the present invention, the concentration under reduced pressure is not particularly limited, and the relative density of the concentrated solution is preferably 1.2 to 1.3.
In the preparation method of the traditional Chinese medicine preparation, relevant parameters of freeze drying are not particularly limited, the preferred freezing temperature is-25 to-30 ℃, and the freezing time is 24 to 48 hours.
Compared with the prior art, the invention has the following beneficial effects:
the invention provides a traditional Chinese medicine composition for treating colitis, which has the characteristics of wide sources of adopted Chinese herbal medicines, low cost, high cure rate and quick response.
Drawings
FIG. 1 is a staining chart of colon sections of mice in the drug groups 1-3;
FIG. 2 is a colon section staining chart of a control group mouse;
FIG. 3 is a staining pattern of a colon section of a blank group of mice.
Detailed Description
In order to make the objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. Several embodiments of the invention are presented in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Example 1
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 10g of coreopsis tinctoria, 5g of sweet wormwood herb, 1g of dried rehmannia root and 2g of sophora flavescens;
secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (with the concentration of 85 wt%) is poured into the mixed medicinal powder, and the mixture is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting the filter residue and filtrate, pouring 250mL of ethanol (the concentration is 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting the filtrate, and combining the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35 hours to obtain the solid medicament.
Example 2
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 11g of coreopsis tinctoria, 5g of sweet wormwood herb, 2g of dried rehmannia root and 1g of lightyellow sophora root;
secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (the concentration is 85 wt%) is poured into the mixed medicinal powder, and the mixed medicinal powder is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting filter residue and filtrate, adding 250mL of ethanol (concentration of 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting filtrate, and mixing the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35h to obtain the solid medicament.
Example 3
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 12g of coreopsis tinctoria, 8g of sweet wormwood, 1g of dried rehmannia root and 1g of radix sophorae flavescentis.
Secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (the concentration is 85 wt%) is poured into the mixed medicinal powder, and the mixed medicinal powder is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting the filter residue and filtrate, pouring 250mL of ethanol (the concentration is 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting the filtrate, and combining the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35 hours to obtain the solid medicament.
Example 4
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 13g of coreopsis tinctoria, 7g of sweet wormwood herb, 2g of dried rehmannia root and 1g of lightyellow sophora root;
secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (the concentration is 85 wt%) is poured into the mixed medicinal powder, and the mixed medicinal powder is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting the filter residue and filtrate, pouring 250mL of ethanol (the concentration is 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting the filtrate, and combining the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35 hours to obtain the solid medicament.
Example 5
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 14g of coreopsis tinctoria, 6g of sweet wormwood, 1g of dried rehmannia root and 2g of sophora flavescens.
Secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (the concentration is 85 wt%) is poured into the mixed medicinal powder, and the mixed medicinal powder is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting filter residue and filtrate, adding 250mL of ethanol (concentration of 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting filtrate, and mixing the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35h to obtain the solid medicament.
Example 6
A traditional Chinese medicine preparation for treating colitis is specifically prepared by the following steps:
firstly, weighing 15g of coreopsis tinctoria, 5g of sweet wormwood, 1g of dried rehmannia root and 2g of sophora flavescens.
Secondly, mixing and crushing the Chinese herbal medicines, and sieving the Chinese herbal medicines by a 200-mesh sieve to obtain mixed medicinal powder;
then, 250mL of ethanol (with the concentration of 85 wt%) is poured into the mixed medicinal powder, and the mixture is soaked for 12 hours at room temperature; heating and refluxing for 2h after soaking; filtering, collecting filter residue and filtrate, adding 250mL of ethanol (concentration of 85 wt%) into the filter residue, heating and refluxing for 1h again, collecting filtrate, and mixing the two filtrates; finally, carrying out reduced pressure concentration on the combined filtrate to obtain a concentrated solution with the relative density of 1.2;
and finally, freezing the concentrated solution at-28 ℃ for 35h to obtain the solid medicament.
The traditional Chinese medicine preparation prepared by the invention is subjected to the following animal experiments:
(1) Grouping animals
80 detergent mice 8 weeks old and 20-25g in weight were selected and divided into 8 groups (10 mice per group) on average, wherein 1 group of mice was a blank group and only distilled water was drunk. In addition, 7 groups of mice freely drunk 3% of DSS solution, and 5 days later, distilled water was changed to 3 weeks, and mice as chronic models of polar colitis were established. The solid preparation prepared in the example is injected into 6 groups of model mice respectively, the injection dosage is 0.25g/Kg, and the solid preparation needs to be dissolved by normal saline before injection. The other model group was a control group and was not injected with any drug. Specifically, the results are shown in Table 1.
TABLE 1
(2) Animal feeding and treatment
After the treated mice are normally fed for 6 days, blood is collected, the mice are sacrificed, the colons of the mice are taken out, excrement is taken out for standby, the length of the colons of each group of mice is measured, the content of the colons is washed out by normal saline, one part of colons is used for preparing colons homogenate, one part of colons is soaked in 10 percent formaldehyde solution for fixation, and dehydration, transparence, paraffin embedding, slicing and HE dyeing are carried out.
(3) Analysis and conclusions
1) Colon length in mice
As can be seen from Table 2, the colon length of the control group mice is much shorter than that of the drug group mice, and the drug group mice can prevent the colon shortening phenomenon of the mice.
TABLE 2
| Length of colon | Injection medicament | |
| Blank spaceGroup(s) | 7.8cm | - |
| Medicament set 1 | 6.5cm | Example 1 |
| Medicine group 2 | 6.6cm | Example 2 |
| Medicament group 3 | 6.8cm | Example 3 |
| Medicine group 4 | 6.7cm | Example 4 |
| Medicine group 5 | 6.3cm | Example 5 |
| Medicine group 6 | 6.9cm | Example 6 |
| Control group | 5.2cm | - |
2) Colon section
FIG. 1 is a section of the colon of each of the mice in the drug groups 1-3 from left to right, and it can be seen from the section that the mucosal layer, submucosal layer, muscular layer and serosal layer of the colon of each of the mice in the drug groups are complete and clear in tissue structure, and the tight connection between cells is normal; the glands are regularly arranged, the goblet cells are rich and no inflammatory cell infiltration exists.
FIG. 2 is a colon section of a control mouse, and it can be seen from FIG. 2 that the colonic muscle layer of the control mouse is seriously damaged; the intercellular space of the lamina propria is increased, inflammatory cell infiltration exists, glands are reduced, arrangement is disordered, goblet cells are increased, and the morphology is abnormal.
The result shows that the traditional Chinese medicine preparation can reduce the colonic inflammation of mice and has a certain repairing effect.
3) Biochemical index of colon
As can be seen from Table 3, the feces, colon homogenates, and serum botulinum toxin LPS were higher in the control mice than in the blank. The feces, colon homogenate and serum botulinum toxin LPS of the mice in the medicament group are lower than those of the control group, which shows that the medicament can reduce the feces, colon homogenate and serum botulinum toxin of the mice and is probably one of the action mechanisms of the medicament for protecting the colon repair of depressed mice.
TABLE 3 measurement of botulinum toxin (LPS) in mouse feces, colon homogenates, serum
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is specific and detailed, but not to be understood as limiting the scope of the present invention. It should be noted that various changes and modifications can be made by those skilled in the art without departing from the spirit of the invention, and these changes and modifications are all within the scope of the invention. Therefore, the protection scope of the present patent should be subject to the appended claims.
Claims (10)
1. A traditional Chinese medicine composition for treating colitis is characterized by comprising the following Chinese herbal medicines by weight:
10-15g of coreopsis tinctoria, 5-8g of sweet wormwood herb, 1-2g of dried rehmannia root and 1-2g of lightyellow sophora root.
2. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
10g of snow chrysanthemum, 5g of sweet wormwood herb, 1g of dried rehmannia root and 2g of lightyellow sophora root.
3. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
11g of snow chrysanthemum, 5g of sweet wormwood herb, 2g of dried rehmannia root and 1g of lightyellow sophora root.
4. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
12g of snow chrysanthemum, 8g of sweet wormwood herb, 1g of dried rehmannia root and 1g of lightyellow sophora root.
5. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
13g of snow chrysanthemum, 7g of sweet wormwood herb, 2g of dried rehmannia root and 1g of lightyellow sophora root.
6. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
14g of coreopsis tinctoria, 6g of sweet wormwood, 1g of dried rehmannia root and 2g of radix sophorae flavescentis.
7. The traditional Chinese medicine composition for treating colitis according to claim 1, is characterized by comprising the following Chinese herbal medicines by weight:
15g of snow chrysanthemum, 5g of sweet wormwood herb, 1g of dried rehmannia root and 2g of lightyellow sophora root.
8. A traditional Chinese medicine preparation for treating colitis, characterized in that it is prepared by processing the traditional Chinese medicine composition according to any one of claims 1 to 7, and the preparation is in the form of decoction, tablet, powder or other medically acceptable preparations.
9. The method of claim 8, comprising the steps of:
weighing the dried Chinese herbal medicines according to a proportion, mixing and crushing the Chinese herbal medicines, and then adding ethanol for soaking treatment; heating reflux extraction is carried out for 1-2h after soaking; filtering, collecting the filter residue and filtrate, extracting the filter residue with alcohol for the second time, and mixing the filtrates; the combined filtrates were concentrated under reduced pressure and freeze-dried to obtain a solid powder.
10. The method according to claim 9, wherein the soaking temperature is 25-45 ℃ and the soaking time is 8-24 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211386428.5A CN115607601A (en) | 2022-11-07 | 2022-11-07 | A Chinese medicinal composition for the treatment of colitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211386428.5A CN115607601A (en) | 2022-11-07 | 2022-11-07 | A Chinese medicinal composition for the treatment of colitis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115607601A true CN115607601A (en) | 2023-01-17 |
Family
ID=84879297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211386428.5A Pending CN115607601A (en) | 2022-11-07 | 2022-11-07 | A Chinese medicinal composition for the treatment of colitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115607601A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1970017A (en) * | 2006-12-21 | 2007-05-30 | 辽宁医学院 | Medicament for treating ulcerative colitis and preparation process thereof |
| CN103099959A (en) * | 2012-12-28 | 2013-05-15 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof |
| CN108057104A (en) * | 2018-02-28 | 2018-05-22 | 邹朋飞 | A kind of Chinese drugs agentia for treating chronic colitis |
-
2022
- 2022-11-07 CN CN202211386428.5A patent/CN115607601A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1970017A (en) * | 2006-12-21 | 2007-05-30 | 辽宁医学院 | Medicament for treating ulcerative colitis and preparation process thereof |
| CN103099959A (en) * | 2012-12-28 | 2013-05-15 | 青岛华仁信息技术开发有限公司 | Traditional Chinese medicine preparation for treating ulcerative colitis and preparation method thereof |
| CN108057104A (en) * | 2018-02-28 | 2018-05-22 | 邹朋飞 | A kind of Chinese drugs agentia for treating chronic colitis |
Non-Patent Citations (1)
| Title |
|---|
| 刘斌;石任兵;朱丽君;: "苦参汤黄酮类成分HPLC指纹图谱及其与组方药味黄芩和苦参的相关性研究", 中国中药杂志, no. 16, pages 1631 - 1634 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520593B (en) | Chinese herba preparation for treating trichomonas vaginitis and preparation method thereof | |
| CN104013929B (en) | Rheumatism pain relief medicine for treating rheumatic arthritis and rheumatoid arthritis and preparation method thereof | |
| CN101933973B (en) | Medicament composition for preventing and treating liver damage | |
| CN105079726A (en) | Medicine composition for treating hemorrhoids and preparation method thereof | |
| CN115607601A (en) | A Chinese medicinal composition for the treatment of colitis | |
| CN101274034B (en) | Traditional Chinese medicine composition for relieving exterior syndrome, clearing heat and detoxicating | |
| CN103655544B (en) | The application of Jaceosidin in preparation prevention or the Fibrotic medicine for the treatment of chronic hepatic injury regulating liver-QI | |
| CN105663945A (en) | Product for treating psoriasis and preparation method of product | |
| CN106237263B (en) | A kind of acute icteric hepatitis and the chronic hepatitis acute onset for the treatment of is with the raised Chinese medicine composition of bilirubin | |
| US20180104298A1 (en) | Zanthoxylum myriacanthum var. pubescens essential oil and application thereof in preparation of drug for treating diabetes | |
| CN100350966C (en) | Chinese medicinal preparation for treating gynecopathy inflammation and its preparing process | |
| CN1899586A (en) | Chinese medicine preparation for treating gynecologic inflammation and its preparing method | |
| Gao et al. | Tibetan medicines and Tibetan prescriptions for the treatment of diabetes mellitus | |
| CN104383050A (en) | Drug for treating rheumatic arthritis through oral taking and external application and preparation method of drug | |
| CN1616011A (en) | Medicinal composition for treating ulcerative colitis and its preparing method | |
| CN104721347A (en) | Externally-applied traditional Chinese medicinal preparation for treating infantile eczema and preparation process of externally-applied traditional Chinese medicinal preparation | |
| CN116036217B (en) | Traditional Chinese medicine compound granule for treating primary liver cancer and preparation method thereof | |
| Mai et al. | Reversine and herbal Xiang–Sha–Liu–Jun–Zi decoction ameliorate thioacetamide-induced hepatic injury by regulating the RelA/NF-κB/caspase signaling pathway | |
| CN102119978A (en) | Composition for relieving exterior syndrome and clearing away heat and toxic materials, and preparation method and detection method thereof | |
| CN112426510B (en) | Composition for treating arthritis and preparation method thereof | |
| CN108057105A (en) | It is a kind of for vegetable oil composition of the auxiliary treatment proliferation of mammary gland and preparation method thereof | |
| CN101837079B (en) | Anti-inflammatory analgesic or anti-inflammatory immune medicinal composition, preparation method and application thereof | |
| CN112675224A (en) | Application of radix ranunculi ternati extract in preparation of medicine for treating diabetic nephropathy renal fibrosis | |
| CN105641438A (en) | Traditional Chinese medicine for treating intestinal collateral blood stasis type ulcerative colitis and preparation method | |
| CN103520540B (en) | Obliterative cholangitis postoperative navel applying agent and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |