CN115576118A - Contact lens with multifunctional point - Google Patents

Abstract

The invention provides a contact lens with a multi-function point, the contact lens with the multi-function point has a front convex surface and a back concave surface, the contact lens with the multi-function point comprises an optical area, a function point area and an edge area, the optical area is positioned in the central area, the function point area surrounds the periphery of the optical area, the edge area surrounds the periphery of the function point area, the front convex surface or the back concave surface is provided with a plurality of function points distributed in a mesh shape, the plurality of function points are provided with releasable dosage forms and distributed in the function point area, and the function points can dissolve the contained releasable dosage forms in tears along with the increase of wearing time of a user.

Description

Contact lens with multifunctional point

Technical Field

The invention relates to the technical field of contact lenses, in particular to a contact lens with functions of protecting components, releasing the components and indicating.

Background

Since the 1950 s, i.e. the commercial use of contact lenses for improving vision, the first generation of contact lenses were made of hard materials, were prone to produce a foreign body sensation for the wearer, had poor oxygen permeability and poor comfort. Later developments in technology have resulted in soft contact lenses based on hydrogels, which are more comfortable for the wearer, extend the wear time of the wearer, and increase the population of wearers and become more popular.

With the continuous evolution of technology, some contact lenses with different functions are appeared, and the technical mechanism of such functional contact lenses can be subdivided into the following types and deletions:

1. contact lenses made by mixing the drug with the monomer: the medicament is mixed with the contact lens monomer, and then processes such as contact lens manufacturing (photo-curing or thermosetting) and lens high-temperature sterilization are carried out, so that the medicament for treatment is easily affected and degraded or deteriorated in the manufacturing process, and the subsequent treatment effect is poor. Secondly, the medicament is mixed in the monomer, and the medicament is affected by the thickness of the lens, and the medicament release speed is not uniform or the medicament is deeply buried in the lens, which also causes poor treatment effect.

2. Immersion drug-releasing contact lenses: the contact lens is soaked in the preserving fluid containing the medicament, and the medicament adhered to the surface of the contact lens is used for releasing the medicament during subsequent wearing, so that the medicament concentration is higher at the initial wearing stage and is greatly reduced subsequently.

3. The lens was perforated with a laser to contain the drug: the lens is formed with holes by laser, and the holes are used to increase the adsorption concentration of the drug and prolong the release time of the drug. However, this method will cause the mechanical strength of the lens to be reduced, and the physical properties of the lens raw material will be affected.

4. Lens release layer: the lens contains a medicament release layer, and the medicament is released by utilizing the release layer. This method causes the swelling property of the lens layer different from that of the drug release layer, and thus the lens is deformed, which affects the yield.

To solve the above problems, the present inventors have considered an improvement and provide a multifunctional contact lens having a protective component, a releasable component, and an indication function.

Disclosure of Invention

The invention mainly aims to provide a multifunctional contact lens with the functions of protecting components, releasing components and indicating, which mainly utilizes a plurality of function points distributed in a network point shape on the surface of the contact lens, not only can stably protect the components and release the components, but also has the function of indicating, does not influence the physical characteristics of the contact lens, and is beneficial to production, manufacture and use.

In order to achieve the purpose, the invention adopts the following technical scheme:

a contact lens with multiple function points is prepared as setting optical zone at central region, surrounding said optical zone by function point zone and surrounding said edge zone at periphery of function point zone, setting multiple function points distributed in net-like point on said front convex surface or back concave surface, setting multiple function points with releasable dosage form and distributing said functional points in said function point zone, enabling contained releasable dosage form to be dissolved in tear liquid by said function points along with increase of wearing time of user.

In a preferred embodiment, the functional dots are embedded in the front convex surface and exposed to the outside to release the releasable dosage form, and the functional dots do not protrude from the front convex surface.

As one of the preferred embodiments, the area of the exposed area of the functional point is 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points is 0.01 mm-0.3 mm.

As one of the preferable embodiments, all the functional point areas occupy 20% to 50% of the front convex surface.

In a preferred embodiment, the multi-function point protrudes from the rear concave surface, and the height of the multi-function point protruding from the rear concave surface is not more than 5 μm.

As one of the preferred embodiments, the multi-function point protrusion area is 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points is 0.01 mm-0.3 mm.

As one of the preferred embodiments, the total area of all the functional dots occupies 20% to 50% of the area of the rear concave surface.

As one of the preferred embodiments, the functional points are transparent.

As one of the preferred embodiments, the functional dots have a color.

As one of the preferred embodiments, the method further comprises a plurality of color sample points, wherein the functional point has a color, each functional point is adjacent to at least one color sample point, and the functional point and the color sample points are different colors.

As a preferred embodiment, the functional dots are arranged side by side with the functional dots of different color samples.

As one of the preferred embodiments, the functional sites are partially stacked with the functional sites of different color samples.

In a preferred embodiment, the functional dots are completely stacked with the functional dots of different color patterns, embedded in the front convex surface and exposed from the surface of the functional dots.

In a preferred embodiment, the functional dots and the functional dots of different color samples are completely stacked together and protrude from the rear concave surface, the functional dots are arranged on the rear concave surface, and the color sample dots are arranged on the functional dots.

As one of the preferred and preferred embodiments, the size of the plurality of functional dots distributed in the functional dot area is not the same.

As one of the preferred and preferred embodiments, the plurality of functional sites have a diameter of 0.03mm to 0.1mm.

As one of the preferred and preferred embodiments, the size of the functional point near the optical zone is smallest, and the size of the functional point near the edge zone is smaller but larger than that near the optical zone.

As one of the preferred and preferred embodiments, the releasable dosage form is present in an amount of 0.001 to 50 weight percent of the functional site.

As a preferred and preferred embodiment, the releasable dosage form in the functional point comprises a hydrophobic component, a hydrophilic component, an amphiphilic component or an active component, the hydrophobic component having a hydrophilic-lipophilic balance (HLB) of between 2 and 8; the hydrophilic component is polyhydric alcohol or its hydrophilic lipophilic balance (HLB value) is 12-18; the amphiphilic component has a hydrophilic-lipophilic balance (HLB) value of 8-14; the active ingredients comprise natural extracts, eye moistening, anti-inflammatory, intraocular pressure lowering, and mydriasis drugs.

As one of the preferred and preferred embodiments, the hydrophobic component preferably has a hydrophilic-lipophilic balance (HLB) value of from 2 to 5; the hydrophilic component is a polyhydric alcohol or a polyhydric alcohol having a Hydrophilic Lipophilic Balance (HLB) value of preferably 13 to 16; the amphiphilic component preferably has a hydrophilic-lipophilic balance (HLB) value of from 9 to 12.

Compared with the prior art, the multifunctional contact lens with the functions of protecting components, releasing components and indicating has the following specific effects:

1. many functional points are distributed in the functional point area, the functional point area surrounds the periphery of the optical area, the function of correcting the vision of the optical area is not influenced, the core value of the contact lens is maintained, the functional points in the functional point area are distributed, components can be protected at ordinary times, many functional points in the functional point area are distributed, the components in the functional points can be released along with the flowing process of tears, the eyes are properly protected or treated according to the released components, many functional points in the functional point area are distributed, the components in the functional points can be released along with the flowing process of tears to generate the change of color appearance, the indicating effect is achieved, and the contact lens has the double effects of correcting the vision, treating and protecting and the like.

2. The component release of the invention is responsible for a plurality of functional points distributed in the functional point area, and the functional points distributed in a mesh shape do not influence the physical strength of the lens because of small area and swelling of single points, so the yield is not reduced because of the mesh functional points in the production process.

3. The functional point of the invention can have color due to the self component of the component contained in the functional point, and the color changes from dark to light along with the release of the component to achieve the effect of color change indication, thus being helpful for the wearer to judge the time for replacing the lens according to the color change situation of the contact lens.

4. The invention can combine the color sample point and the function point, so that the color change effect is more obvious.

5. The invention can utilize a plurality of functional points with different sizes to ensure that the concentration of the components in the eyes reaches the set value at the initial stage of wearing the contact lens so as to obtain the required health care or treatment effect, and then the functional points with large sizes still gradually and smoothly release the components to prolong the action time of the components to achieve the effect of hours or days, thereby meeting the design requirement.

Drawings

FIG. 1 is a sectional view of a first embodiment of a contact lens with multiple functional points according to the present invention.

FIG. 2 is a schematic cross-sectional view of a first embodiment of a contact lens with multiple functional points of the present invention.

Fig. 3 is a front view of a first embodiment of the contact lens with multiple functional points of the present invention.

FIG. 4 is an enlarged partial cross-sectional view of a first embodiment of the contact lens with multiple functional points of the present invention.

FIG. 5 is a cross-sectional view of a second embodiment of a contact lens with multiple functional points of the present invention.

Fig. 6 is an enlarged partial cross-sectional view of a second embodiment of the contact lens with multiple functional points of the present invention.

Fig. 7 is a partially enlarged view of a third embodiment of the contact lens with multiple functional points of the present invention.

FIG. 8 is a schematic diagram showing the distribution of functional dots and color samples in a third embodiment of the contact lens with multiple functional dots of the present invention.

FIG. 9 is a schematic diagram of the distribution of functional dots and color samples in a fourth embodiment of the contact lens with multiple functional dots of the present invention.

FIG. 10 is a schematic diagram of the distribution of functional dots and color samples in a fifth embodiment of the contact lens with multiple functional dots of the present invention.

FIG. 11 is a schematic diagram showing the distribution of functional dots and color samples in a sixth embodiment of the contact lens with multiple functional dots of the present invention.

FIG. 12 is a schematic diagram showing the distribution of functional dots and color samples in a seventh embodiment of the contact lens with multiple functional dots of the present invention.

FIG. 13 is a schematic diagram illustrating the distribution of functional dots and color samples in an eighth embodiment of the contact lens with multiple functional dots of the present invention.

Fig. 14 is a front view of a ninth embodiment of the contact lens with multiple functional points of the present invention.

Fig. 15 is an enlarged view of the radial distribution of a plurality of functional points of the ninth embodiment of the contact lens with multiple functional points according to the present invention.

Description of the drawings:

1, contact lenses;

11, a front convex surface;

12, back concave surface;

13, an optical zone;

14, functional point area;

15, an edge area;

16, function points;

17, color sample points;

r1 is the diameter of the inner ring;

r2 is the diameter of the outer ring;

l is wide.

Detailed Description

The technical solution of the present invention will be clearly and completely described below with reference to the specific embodiments and the accompanying drawings. It will be understood that when an element is referred to as being "mounted on" or "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. In the illustrated embodiment, the directions indicate that up, down, left, right, front, rear, and the like are relative, and are used to explain that the structures and movements of the various components are relative in this case. These representations are appropriate when the components are in the positions shown in the figures. However, if the description of the location of an element changes, it is believed that these representations will change accordingly.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1,2 and 3, which are a sectional view, a sectional view and a front view of a contact lens 1 of the invention having a convex anterior surface 11 and a concave posterior surface 12, the contact lens 1 includes an optical zone 13, a functional point zone 14 and a peripheral zone 15. The optical zone 13 is located in the central region, the functional point zone 14 surrounds the periphery of the optical zone 13, and the edge zone 15 surrounds the periphery of the functional point zone 14. The front convex surface 11 is provided with a plurality of function points 16 distributed in a network shape, a plurality of function points 16 are distributed in the area of the function point area 14, the function points 16 are provided with a releasable dosage form, and the releasable dosage form is dissolved and released along with the increase of wearing time of a user. Therefore, the functional points 16 distributed in the shape of a dot can smoothly and uniformly release the components at the right time, maintain the average component concentration in the tears of the eyes, and improve the yield of the production without affecting the structural characteristics of the contact lens 1 in the production and manufacturing process.

The structure of the components will be described in detail as follows:

the optical zone 13 is located in the central area of the contact lens 1, which is the main area for correcting vision, and can be spherical, aspherical, hyperbolic, etc., and this part is designed correspondingly according to the vision correction requirement. The functional point region 14 is a non-optical correction lens surrounding the optical region 10, and the inner circle diameter R1 of the functional point region 14 is 5.0-8.0 mm, and the outer circle diameter R2 is 8.5-13.5 mm. The edge region 15 is the outermost portion relative to the geometric center of the lens, and generally, the width L of the edge region 15 is about 0.45mm to 0.55mm.

The invention is characterized in that: the front convex surface 11 or the back concave surface 12 of the area where the functional point region 14 is located is provided with a plurality of functional points 16 distributed in a mesh shape. As shown in fig. 1-4, in the present embodiment, the functional point 16 is embedded in the front convex surface 11 and exposed to the outside, which helps release the releasable component, and the functional point 16 does not protrude from the surface of the front convex surface 11, which also reduces discomfort of eyelid closing or opening. In order not to affect the physical characteristics of the lens, the exposed area of each functional point 16 is 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points 16 is 0.01 mm-0.3 mm. The total area of all the functional points 16 accounts for 20-50% of the area of the front convex surface 11. In the present embodiment, the functional dots 16 are first coated on the surface of the mold by printing, then the single body of the contact lens material is molded in the mold, and then the contact lens is made into the finished contact lens by other subsequent steps, such as photo-curing or thermal-curing, so that the functional dots 15 are embedded in the front convex surface 11 and the surface is exposed.

Fig. 5 and 6 are a cross-sectional view and a partial enlarged view of a second embodiment of the present invention. The functional dots 16 protrude from the surface of the posterior concave surface 12 with a height of no more than 5 μm, which can reduce discomfort of eyelid closing or opening, and since the plurality of functional dots 16 protrude from the posterior concave surface 12, when the contact lens 1 is worn, a gap exists between the posterior convex surface 12 and the surface of the eyeball, which is helpful for tears to flow around the plurality of functional dots 16 to release components, so that the concentration of the components can meet the design value. In addition, in order not to affect the physical properties of the lens, each functional point 16 protrudes from the lens with an area of 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points 16 is 0.01 mm-0.3 mm. The total area of all the functional dots 16 occupies 20 to 50% of the area of the rear concave surface 12. In the present embodiment, theThe functional dots 16 are printed on the surface of the posterior concave surface 12 after the contact lens is molded, so that the molded functional dots 16 can protrude from the surface of the posterior concave surface 12.

The shape of the functional point 16 exposed on the front convex surface 11 or protruding the rear concave surface 12 is a geometric figure, such as a circle, an ellipse, an arc, a polygon, a rectangle, etc., but not limited thereto.

In the above embodiments, the functional dots 16 are formed on the surface of the contact lens 1 by printing, and the functional dots 16 are composed of a releasable agent and a non-releasable material, wherein the releasable agent accounts for 0.001-50% of the functional dots 16 by weight. As shown in the following Table I, the non-releasable species include silicon-based monomers, reactive monomers, reaction initiators, and cross-linking agents. Wherein the silicon-based monomer accounts for 50-75% of the functional point 16 by weight, and comprises: polydimethylsiloxane (PDMS), (3-glycidoxypropyl) trimethoxysilane [ (3-glycidoxypropyl) trimethoxysilane, GPTMS]3- [ tris (trimethylsiloxy) silyl ] silane]Propyl methacrylate [3- [ tris (trimethyliloxy) sily]propyl methacrylate，TRIS]At least one of them. The reaction monomer accounts for 1 to 15 percent of the weight of the functional point 16 and comprises the following components: 2-Hydroxyethyl methacrylate (HEMA), N-Dimethylacrylamide (DMA), glycidyl Methacrylate (GMA), and methyl Methacrylate (MAA). The reaction initiator accounts for 1-15% of the functional point 16 by weight and comprises: 2-Hydroxy-2-methylpropiophenone (2-Hydroxy-2-methylpropiophenone, trade name: UVC-1173), 1,2' -Bis (2-chlorophenyl) -tetraphenylimidazole (2, 2' -Bis (2-chlorophenyl) -4,4', 5' -tetraphenyl-1,2' -biimidazole, trade name:

900 1-hydroxycyclohexylphenylketone (1-Hydroxycyclohexylphenyl ketone, trade name: flecure 184). The cross-linking agent accounts for 1-3% of the functional site 16 by weight and comprises Trimethylolpropane trimethacrylate (Trimethylolpropane trimete)thracrylate, TMPTMA), N '-Methylenebisacrylamide (N, N' -Methylenebisacrylamide, NMBA).

As shown in table 2 below, the releasable dosage form includes a hydrophobic component, a hydrophilic component, an amphiphilic component, or an active ingredient. The hydrophobic component has a hydrophilic-lipophilic balance (HLB) value of from 2 to 8, preferably from 2 to 5, and comprises, in an amount of from 0 to 1% by weight of the releasable dosage form: castor Oil (Castor Oil), soybean Oil (Soyabean Oil), cottonseed Oil (cottenseed Oil), orange Oil (Sweet orange Oil), peanut Oil (peanout Oil), peanut Oil (Arachis Oil), sesame Oil (Sesame Oil), sunflower Oil (Sun flower seed Oil), rapeseed Oil (Rapeseed Oil). The hydrophilic component is a polyol or a hydrophilic-lipophilic balance (HLB) value of the polyol or the polyol having HLB of 12-18, preferably HLB of 13-16, and is present in an amount of 10-50 wt% of the releasable dosage form, and comprises glycerin (Glycerol), ethylene Glycol (Ethylene Glycol), propylene Glycol (Propylene Glycol), butylene Glycol (Butylene Glycol), butanetriol (Trihydroxybutane), and Polyethylene Glycol cetyl ether (Polyethylene Glycol hexane ether, trade name:

58 Polyoxyethylene (20) oleyl ether (Polyoxyethylene (20) oleyl ether, trade name:

o20), polyoxyethylene (10) cetyl ether (polyoxyethyylene (10) cetyl ether, trade name:

c10 Polyoxyethylene (100) stearyl ether (Polyoxyethylene (100) stearyl ether, trade name:

s100) at least one of the above. The amphiphilic component has a hydrophilic-lipophilic balance (HLB) value of from 8 to 14, preferably from 9 to 12, and comprises from 50 to 90% by weight of the releasable dosage form: polyethylene glycol 400 (Polyethylene glycol)400,peg-400), tween 40 (Tween-40), tween 60 (Tween-60), tween 80 (Tween-80), caprylocaproyl macrogolglycerides (Caprylocaproyl Polyoxyl-8glycerides, trade name:

) Polyethylene glycol monostearate (Polyethylene glycol monostearate, trade name:

) Polyoxyethylene hydrogenated castor oil (35) (trade name:

EL), polyoxyethylene Hydrogenated Castor Oil (40) (PEG-40 Hydrogenated Castor Oil, trade name:

RH 40), polyoxyethylene Hydrogenated Castor Oil (60) (PEG-60 Hydrogenated Castor Oil, trade name:

RH 60). The active component is natural extract (such as plant extract and biological extract), anti-inflammatory, intraocular pressure reducing and mydriasis drug, and the active component accounts for 0-5% of the weight of the releasable dosage form, and comprises: pilocarpine (Pilocarpine), curcumin (Curcumin), beta-Carotene (B-Carotene), astaxanthin (Astaxanthin), cyclosporine A (Cyclosporin A), brimonidine (Brimonidine), latanoprost (Latanoprost), brinzolamide (Brinzolamide), travoprost (Travoprost).

Table 1 shows the composition and proportion of functional points

Table 2 shows the composition and ratio of the components of the releasable dosage form

Furthermore, the functional dots 16 of the present invention can be transparent bodies, which are distributed in the functional dot region 14, but the transparent bodies have the same color as the contact lens 1 itself, so that the appearance of the eyes of the wearer is not different after wearing. However, without being limited thereto, the functional dots 16 can also have a color that is caused by the releasable component of the dosage form, and the color changes from dark to light as the released component decreases, thereby achieving the color change indication effect, which also helps the wearer to determine the time for changing the lens according to the color change of the contact lens 1.

As shown in fig. 7, in order to make the color change effect more obvious, the present invention further includes a plurality of color dots 17, each of the functional dots 16 is adjacent to the color dot 17, the functional dots 16 and the color dots 17 are different colors, and the colors have complementary color functions, so as to make the color development effect of the contact lens 1 better. Moreover, the functional dots 16 and the color samples 17 of adjacent and different colors achieve a color mixing effect, for example, the functional dots 16 are yellow and the color samples 17 are blue, so that the appearance of the releasable dosage form is visually green, and then the color of the releasable dosage form 16 gradually releases the color sample 15 from being changed from being dark to light, thereby achieving the dual effects of component release and color change required by the present invention.

The functional dots 16 and the color pattern dots 17 are formed by printing in the mold during the initial production process, and then the single contact lens is formed in the mold, as shown in fig. 8, 9 and 10, the functional dots 16 and the color pattern dots 17 are formed in a dot-like distribution on the front convex surface 11 of the contact lens 1 by the subsequent processing. The functional dots 16 and the color sample dots 17 have two complementary different colors, and are adjacent to each other in the following ways. As shown in fig. 8, the functional dots 16 and the color sample dots 17 are arranged adjacent to each other. As shown in fig. 9, the functional dots 16 and the color pattern dots 17 are partially stacked, and the surface of the functional dots 16 is exposed on the front convex surface 11. As shown in figure 10, the functional dots 16 and the color sample dots 17 are in a fully stacked manner with the functional dots 16 surface exposed on the front convex surface 11 in such a manner that the initial color development is dominated by the functional dots 16 and then by the color of the color sample dots 17 as the releasable dosage form is gradually released and the functional dots become lighter.

Furthermore, the functional dots 16 and the color pattern dots 17 can also be distributed on the posterior concave surface 12, as shown in fig. 11, 12 and 13, in such a way that after the single contact lens is molded, the multi-functional dots 16 and the color pattern dots 17 are printed on the posterior concave surface 12 in a dot-like distribution, and then are processed and shaped to prevent peeling. The functional dots 16 and the color sample dots 17 have two complementary different colors, and are adjacent to each other in the following ways. As shown in fig. 11, the functional dots 16 and the color dots 17 are disposed adjacent to each other and protrude from the rear concave surface 12. As shown in fig. 12, the functional dots 16 and the color dots 17 are partially stacked, and the contact area between the functional dots 16 and the rear concave surface 12 is larger than the contact area between the color dots 17 and the rear concave surface 12. As shown in fig. 13, the functional dots 16 and the color dots 17 are completely stacked, and the functional dots 16 are disposed on the rear concave surface 12, and the color dots 17 are disposed on the functional dots 16, so that the initial color development is mainly performed by the functional dots 16, and the human eye sees the color development effect of the functional dots 16 behind the contact lens 1, and then the color development effect is performed by the color dots 17 after the releasable dosage form is changed to light.

Fig. 14 and 15 are diagrams of a ninth embodiment of the present invention and a schematic diagram of radial distribution of the functional points 16 in the present embodiment. In the present example mainly the shape of the functional point 16 is changed. The functional dots 16 are distributed in the functional dot region 14 with different sizes, and the size of the functional dots 16 gradually increases from the inner circle to the outer circle, then reaches a maximum value at a position of a radius of 3/4, and then gradually decreases. In other words, the functional point 16 near the optical zone 13 has the smallest size, and the functional point 16 near the edge zone 15 has the smallest size but larger size than that near the optical zone 13, and in this embodiment, the minimum diameter of the functional point 16 is 0.03mm, and the maximum diameter is 0.1mm. The functional dots 16 of different sizes are distributed only on the front convex surface 11 or the rear concave surface 12. The total area of all the functional points 16 accounts for 30 to 40 percent of the area of the front convex surface 11 or the back concave surface 12. In addition, the mode is convenient in production.

The design advantages of the above embodiment are: the contact lens 1 can be worn in the initial stage, a large amount of releasable components are released by dissolving the dense small-size functional points 16 and tears, the concentration of the active components in the eyes in the initial stage of wearing can reach a set value, thereby achieving the required health care or treatment effect, then the large-size functional points 16 still gradually and smoothly release the releasable components, the action time of the active components is prolonged to achieve the effect of hours or days, the good health care or treatment effect is maintained, and then the multifunctional contact lens with the protection components, the release components and the indication functions can be replaced according to whether the contact lens 1 is discolored or not, so that the aim of designing the multifunctional contact lens with the protection components, the release components and the indication functions is achieved.

The lenses of the invention may be made using lens-forming materials suitable for use in the manufacture of ophthalmic lenses, including but not limited to, ophthalmic lenses, contact lenses and intraocular lenses. Materials that can be used to make soft contact lenses include, but are not limited to: silicone elastomers, silicone-containing macromers, hydrogels, silicone-containing hydrogels, and the like and combinations thereof. More preferably the surface is a siloxane or contains siloxane functionality including, but not limited to, polydimethylsiloxane macromers, methacryloxypropyl polyalkyl siloxanes and mixtures thereof, silicone hydrogels or hydrogels.

In summary, the multifunctional contact lens with protection component, release component and indication function of the present invention is to form the mesh-like functional points 16 on the front convex surface 11 or the back concave surface 12 of the contact lens 1, which is helpful to stably and uniformly release the releasable dosage form to the tear at proper time, maintain the average active component concentration in the eye tear, and improve the yield of production without affecting the structural characteristics of the contact lens 1 in production and manufacturing. In addition, the functional point 16 can be used for releasing the color of the preparation, and the color sample point 17 is arranged close to the functional point 16, so that the color changes from thick to thin along with the release of the releasable preparation to achieve the required color change effect, thereby being beneficial to identifying the time for replacing the contact lens by a wearer and leading the active ingredient to exert the optimal health care or treatment effect, and meeting the requirements of patent applications.

The above description is only for the preferred embodiment of the present invention, and is not intended to limit the scope of the embodiment of the present invention. All equivalent changes and modifications made according to the claims of the present invention are covered by the claims of the present invention.

Claims (22)

1. A contact lens having a multi-function point, wherein said multi-function point contact lens has a convex front surface and a concave back surface, said multi-function point contact lens comprises an optical zone, a function point zone, and an edge zone, wherein said optical zone is located in the central area, said function point zone surrounds the optical zone, said edge zone surrounds the function point zone, said convex front surface or concave back surface has a plurality of function points distributed in the form of a mesh, said plurality of function points have a releasable dosage form and are distributed in said function point zone, said function points allow said releasable dosage form to dissolve in tear fluid as the wearing time of the user increases.

2. The contact lens having a multifunctional spot according to claim 1, wherein the functional spot is embedded in the anterior convex surface and exposed on a surface thereof to provide a function of releasing the releasable dosage form, and wherein the functional spot does not protrude from the anterior convex surface.

3. The contact lens with multiple functional points of claim 2, wherein the area of the exposed functional point area is 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points is 0.01 mm-0.3 mm.

4. The contact lens having a multifunctional point according to claim 2, wherein the total area of all the functional points is 20 to 50% of the area of the front convex surface.

5. The contact lens with a multifunctional point according to claim 1, wherein the multifunctional point protrudes from the posterior concave surface, and the multifunctional point protrudes from the posterior concave surface by a height of not more than 5 μm.

6. The contact lens with a multifunctional point according to claim 5, wherein the multifunctional point protrusion area is 0.0075mm ² ～0.75mm ² And the distance between two adjacent functional points is 0.01 mm-0.3 mm.

7. The contact lens having a multifunctional point according to claim 5, wherein the total area of all the functional points occupies 20 to 50% of the area of the posterior concavity.

8. The contact lens with a multifunctional spot according to claim 1, wherein the functional spot is a transparent body.

9. The contact lens having a multifunctional point according to claim 1, wherein said functional point has a color.

10. The contact lens having a plurality of functional dots according to claim 1, further comprising a plurality of color sample dots, wherein the functional dots have a color, each functional dot is immediately adjacent to at least one of the color sample dots, and the functional dots are different colors from the color sample dots.

11. The contact lens having a plurality of functional dots according to claim 10, wherein the functional dots and the color dots are arranged side by side.

12. The contact lens having a plurality of functional dots according to claim 10, wherein the functional dots are partially stacked with the color sample dots.

13. The contact lens having a plurality of functional dots according to claim 10, wherein the functional dots are completely stacked on the color dots and embedded in the front convex surface and exposed from the functional dot surface to the front convex surface.

14. The contact lens having a plurality of functional dots according to claim 10, wherein the functional dots are completely stacked on the color dots protruding from the concave-back surface, the functional dots are disposed on the concave-back surface, and the color dots are disposed on the multifunctional dots.

15. The contact lens with multiple functional points according to claim 1, wherein the functional points are distributed in different sizes in the functional point region.

16. The contact lens having a plurality of functional dots according to claim 14, wherein the plurality of functional dots have a diameter of 0.03mm to 0.1mm.

17. The contact lens having a multiple function point of claim 14, wherein said functional point dimension is smallest proximate said optical zone, and wherein said functional point dimension is smaller proximate said edge zone but larger proximate said optical zone.

18. The contact lens having a multifunctional point according to claim 1, wherein said releasable dosage form is present in an amount of 0.001 to 50 weight percent of said functional point.

19. The contact lens having a multifunctional spot according to claim 1, wherein the releasable dosage form in the functional spot comprises a hydrophobic component having a Hydrophilic Lipophilic Balance (HLB) of between 2-8, a hydrophilic component, an amphoteric component, or an active component; the hydrophilic component is polyhydric alcohol or its hydrophilic lipophilic balance (HLB value) is 12-18; the amphiphilic component has a hydrophilic-lipophilic balance (HLB) value of 8-14; the active ingredients comprise natural extracts, eye moistening, anti-inflammatory, intraocular pressure lowering, and mydriasis drugs.

20. The contact lens having a multifunctional point according to claim 18, wherein the hydrophobic component has a hydrophilic-lipophilic balance (HLB) value preferably ranging from 2 to 5.

21. The contact lens having a multifunctional point according to claim 18, wherein the hydrophilic component is a polyhydric alcohol or a polyhydric alcohol having a Hydrophilic Lipophilic Balance (HLB) preferably ranging from 13 to 16.

22. The contact lens having a multifunctional point according to claim 18, wherein the amphiphilic component has a preferred value of hydrophilic-lipophilic balance (HLB) between 9 and 12.

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