CN115541905A - Sample analyzer and detection method thereof - Google Patents

Sample analyzer and detection method thereof Download PDF

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Publication number
CN115541905A
CN115541905A CN202210019162.4A CN202210019162A CN115541905A CN 115541905 A CN115541905 A CN 115541905A CN 202210019162 A CN202210019162 A CN 202210019162A CN 115541905 A CN115541905 A CN 115541905A
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China
Prior art keywords
reagent
sample
station
reaction
needle assembly
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CN202210019162.4A
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Chinese (zh)
Inventor
郭俊游
卢江涛
华德运
周军
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Shenzhen Reetoo Biotechnology Co Ltd
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Shenzhen Reetoo Biotechnology Co Ltd
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Publication of CN115541905A publication Critical patent/CN115541905A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a sample analyzer and a detection method thereof, the sample analyzer comprises a reaction mechanism, a reagent storage mechanism, a reagent needle assembly, a detection mechanism and a controller, wherein the reaction mechanism is used for bearing a reaction container containing a sample, the reaction mechanism is respectively provided with a sample adding station, a reagent adding station and a detection station, the reagent storage mechanism is used for bearing the reagent container, the reagent needle assembly is used for collecting the reagent in the reagent container and adding the reagent into the reaction container, the detection mechanism is arranged adjacent to the reaction mechanism, and the controller is used for controlling the reaction mechanism to rotate so as to convey the reaction container to the sample adding station to receive the sample, convey the sample to the reagent adding station to receive the reagent and convey the sample to the detection station to perform primary detection on the sample, wherein when the last sample is conveyed to the detection station to perform primary detection, the current sample is conveyed to the reagent adding station, so that the two samples can simultaneously realize different operations in the reaction mechanism, the detection time is shortened, and the detection efficiency is improved.

Description

Sample analyzer and detection method thereof
Technical Field
The invention relates to the technical field of medical instruments, in particular to a sample analyzer and a detection method of the sample analyzer.
Background
A sample analyzer generally includes a sample processing device such as a mixing mechanism, a transport mechanism, a sampling mechanism, and a reaction mechanism, and can perform various operations such as mixing, transporting, sampling, and reacting with a reagent on a sample to detect the sample.
When a sample is reacted and detected in the reaction mechanism, generally, after the current sample is mixed with a reagent and the detection is completed, the next sample is sent into the reaction mechanism and then mixed and detected, and the like, so that the time consumption is long, and the detection efficiency is low.
Disclosure of Invention
The invention provides a sample analyzer and a detection method of the sample analyzer, and aims to solve the technical problem that in the prior art, a reaction mechanism of the sample analyzer is low in detection efficiency.
In order to solve the above technical problem, one technical solution adopted by the present invention is to provide a sample analyzer, including:
the reaction mechanism is provided with a plurality of container positions, the container positions are used for bearing reaction containers, the reaction containers are used for loading samples, and the reaction mechanism is respectively provided with a sample adding station, a reagent adding station and a detection station along the circumferential direction of the reaction mechanism;
the reagent storage mechanism is arranged adjacent to the reaction mechanism and is used for bearing a reagent container filled with a reagent;
a reagent needle assembly disposed adjacent to the reaction mechanism and the reagent storage mechanism for collecting the reagent in the reagent container and adding the reagent to the reaction container;
a detection mechanism disposed adjacent to the reaction mechanism;
and the controller is used for controlling the reaction mechanism to rotate so as to transport the reaction container to the sample adding station to receive the sample, to the reagent adding station to receive the reagent and to the detection station to detect the sample for one time, wherein when the previous sample is transported to the detection station to detect for one time, the current sample is transported to the reagent adding station.
In order to solve the above technical problem, another technical solution adopted by the present invention is to provide a detection method of a sample analyzer, including:
controlling a reaction mechanism to rotate so as to transport a reaction container in the reaction mechanism to a sample adding station to receive a sample;
controlling the reaction mechanism to rotate to transport the reaction container to a reagent adding station to receive a reagent collected by a reagent needle assembly from a reagent storage mechanism;
controlling the reaction mechanism to rotate to transport the reaction container to a detection station so as to perform primary detection on the sample through the detection mechanism;
when the previous sample is transported to the detection station for primary detection, the current sample is transported to the reagent adding station.
The sample analyzer comprises a reaction mechanism, a reagent storage mechanism, a reagent needle assembly, a detection mechanism and a controller, wherein the reaction mechanism is provided with a plurality of container positions, the container positions are used for bearing reaction containers, the reaction containers are used for loading samples, the reaction mechanism is respectively provided with a sample adding position, a reagent adding position and a detection position along the circumferential direction of the reaction mechanism, the reagent storage mechanism is arranged adjacent to the reaction mechanism and used for bearing reagent containers filled with reagents, the reagent needle assembly is arranged close to the adjacent positions of the reaction mechanism and the reagent storage mechanism and used for collecting the reagents in the reagent containers and adding the reagents into the reaction containers, the detection mechanism is arranged close to the reaction mechanism, and the controller is used for controlling the reaction mechanism to rotate so as to convey the reaction containers to the sample adding position to receive the samples, convey the samples to the reagent adding position to receive the reagents and convey the reagents to the detection position to carry out primary detection on the samples.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without inventive efforts, wherein:
FIG. 1 is a schematic perspective view of an embodiment of a sample analyzer according to the present invention;
FIG. 2 is a schematic top view of a portion of the structure of an embodiment of a sample analyzer of the present invention;
FIG. 3 is a perspective view of a portion of the structure of an embodiment of a sample analyzer of the present invention;
FIG. 4 is a perspective view of a portion of the structure of an embodiment of a sample analyzer of the present invention;
FIG. 5 is a perspective view of a portion of the sample analyzer embodiment of the present invention;
FIG. 6 is a schematic perspective view of a portion of the structure of an embodiment of a sample analyzer of the present invention;
FIG. 7 is a schematic flow chart of an embodiment of a detection method of the sample analyzer of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
The terms "first", "second" and "first" in this application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or to implicitly indicate the number of technical features indicated. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise. Furthermore, the terms "include" and "have," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus. And the term "and/or" is only one kind of association relationship describing the associated object, and means that there may be three kinds of relationships, for example, a and/or B, and may mean: a exists alone, A and B exist simultaneously, and B exists alone. In addition, the character "/" herein generally indicates that the former and latter associated objects are in an "or" relationship.
Referring to fig. 1 and 2, a first embodiment of a sample analyzer 10 according to the present invention includes a housing 101, the housing 101 forms an accommodating cavity, the sample analyzer 10 further includes a mixing mechanism 100, a sampling mechanism 200, a conveying mechanism 300, a controller 400 and a reaction mechanism 500, the mixing mechanism 100, the conveying mechanism 300, the sampling mechanism 200, and the reaction mechanism 500 are disposed in the accommodating cavity, the controller 400 is configured to control the mixing mechanism 100 to mix samples, the conveying mechanism 300 is configured to convey the mixed samples to the sampling mechanism 200, and the sampling mechanism 200 is configured to sample the mixed samples and convey the mixed samples to the reaction mechanism 500 for reaction detection.
In this embodiment, the sample may be a sample, an intermediate product or an end product of a mixing or reaction of the sample with a diluent or a reagent, or the like.
In the present embodiment, the controller 400 may include a driving board or the like.
In this embodiment, the control device may further include a fluid path mechanism, such as a motor, a syringe, etc.
In other embodiments, the control device may further include an MCU (micro controller Unit), etc., which is not limited herein.
Referring to fig. 3 to 6 together, in this embodiment, the sample analyzer 10 further includes a reagent storage mechanism 600, a reagent needle assembly 710, and a detection mechanism 720, the reaction mechanism 500 is located on a side of the sampling mechanism 200 away from the mixing mechanism 100, and is provided with a plurality of container positions, the container positions are used for carrying the reaction container 510, the reaction container 510 is used for loading a sample, the reaction mechanism 500 is respectively provided with the sample adding position 220, the reagent adding position 520, and the detection position 530 along a circumferential direction thereof, the reagent storage mechanism 600 is arranged adjacent to the reaction mechanism 500, the reagent storage mechanism 600 includes a plurality of reagent storage positions for carrying reagent containers 610 containing reagents to be reacted to store the reagents, the reagent needle assembly 710 is arranged adjacent to the reaction mechanism 500 and the reagent needle assembly 600, and the reagent needle assembly 710 can move between the reagent storage mechanism 600 and the reaction mechanism 500, to suck the reagent in the reagent container 610 of the reagent storage mechanism 600 and to deliver the reagent into the reaction container 510 of the reaction mechanism 500 to mix the reagent with the sample for subsequent detection at the detection station 530, the detection mechanism 720 is disposed adjacent to the reaction mechanism 500, the position of the reaction mechanism 500 corresponding to the detection mechanism 720 is the detection station 530, the detection mechanism 720 is used to detect the reacted sample, the controller 400 is used to control the reaction mechanism 500 to rotate to transport the reaction container 510 to the sample loading station 220 to receive the sample, to transport the sample to the reagent loading station 520 to receive the reagent, to transport the detection station 530 to perform a detection on the sample, wherein when the previous sample is transported to the detection station 530 to perform a detection, the current sample is transported to the reagent loading station 520, so that two samples can simultaneously perform different operations at the reaction mechanism 500, the detection time is reduced, and the detection efficiency is improved.
In this embodiment, the reagent needle assembly 710 is disposed adjacent to the reagent storage mechanism 600 and the reaction mechanism 500 such that the reagent adding station 520 is disposed adjacent to the reagent storage mechanism 600 in the circumferential direction of the reaction mechanism 500, and the detecting station 530 is disposed at a position opposite to the reagent adding station 520, so that two samples can be simultaneously subjected to the reagent adding process and the detecting process.
In this embodiment, the plurality of container positions are sequentially incremented by the reference number along the circumferential direction of the reaction mechanism 500 to form a container position number, the difference between the two adjacent container positions is 1, and the difference between the container position number of the previous sample and the container position number of the current sample is half of the total container position number, so that the two samples can be simultaneously subjected to reagent adding and detection processes in the reaction mechanism 500, and the operation of the reagent needle assembly 710 and the detection mechanism 720 is facilitated, thereby avoiding mutual interference and improving reliability.
In this embodiment, the reaction vessels 510 sequentially transported to the inspection station 530 for one inspection have non-adjacent vessel positions.
Referring to fig. 2, for example, 48 container positions are provided on the reaction mechanism 500, and the number of the container positions is sequentially increased from No. 1 to No. 48 along the circumferential direction, when the reaction container 510 on the No. 1 container position is detected once at the detection station 530, the reaction container 510 on the No. 24 container position is located at the reagent adding station 520, when the sample in the reaction container 510 on the No. 1 container position is detected once, the No. 24 container position is moved to the detection station for detection once, and so on.
In this embodiment, a cleaning station 540 may be further disposed on the circumferential direction of the reaction mechanism 500, and the numbers of the container positions sequentially transported to the reagent adding station 520 for adding the reagent and/or sequentially transported to the sample adding station 220 or sequentially transported to the cleaning station 540 are all not adjacent, and are increased or decreased in an arithmetic rule.
In this embodiment, the controller 400 is further configured to control the reaction mechanism 500 to rotate to transport the sample that has undergone one-time detection to the detection station 530 after the current sample reaches the reagent adding station 520 and before the current sample reaches the detection station 530 for one-time detection, so as to perform a second-time detection on the sample that has undergone the first-time detection, and to calculate a final detection result from data of the first-time detection and data of the second-time detection.
In this embodiment, the time from the current sample being added to the sample adding station 220 to the next sample being added to the sample adding station 220 is counted as one cycle, and the time between the detection of the sample for the second time and the detection of the sample for the second time is at least six cycles, so that the sample and the reagent in the sample can be further mixed and reacted sufficiently, and the reaction efficiency can be improved by allowing the next sample after the detection of the current sample for the first time to enter the reaction mechanism 500 for reagent addition, detection and the like, so as to realize parallel operation of a plurality of samples.
In this embodiment, the reagents may include a first reagent and a second reagent, and the controller 400 is configured to control the reaction mechanism 500 to rotate after the reaction vessel 510 receives the sample, so that the reaction vessel 510 reaches the reagent adding station 520 to receive the first reagent and the second reagent.
In this embodiment, the controller 400 controlling the reaction mechanism 500 to rotate so that the reaction vessel 510 reaches the reagent adding station 520 to receive the first reagent and the second reagent may include:
the controller 400 controls the reagent needle assembly 710 to collect a portion of the sample and the first reagent, and controls the reaction mechanism 500 to rotate to the reagent adding station 520 loaded with the empty reaction vessel 510, controls the reagent needle assembly 710 to add a portion of the sample and the first reagent to the empty reaction vessel 510, and controls the reagent needle assembly 710 to add the second reagent to the reaction vessel 510 to mix with the sample and the first reagent, thereby achieving mixing of the sample and the first and second reagents.
In this embodiment, the controller 400 controls the reagent needle assembly 710 to collect the portion of the sample and the first reagent including:
the controller 400 controls the reagent needle assembly 710 to arrive at the reagent storage mechanism 600 to collect and store the first reagent, and then controls the reagent needle assembly 710 to arrive at the reagent adding station 520 to collect a part of the sample, the operation process is simple, the first reagent and the sample can be uniformly mixed in the reagent needle assembly 710, compared with the method of respectively collecting the first reagent and sending the first reagent into the reaction container 510 and collecting the sample and sending the sample into the reaction container 510, the method can avoid the reagent needle assembly 710 from rotating for many times, and reduce errors caused by positioning and detection errors caused by overflow of the sample or the reagent in the rotating process.
In this embodiment, the controller 400 may further control the reagent needle assembly 710 to aspirate and spit the first reagent and the sample in the reaction container 510 for a plurality of times after the first reagent and the sample are collected, so as to achieve uniform mixing of the first reagent and the sample.
In other embodiments, the reagent needle assembly 710 may also be directly connected to the conduit to receive the first reagent, which may further simplify the process of mixing the samples and improve the operation efficiency.
In other embodiments, the controller 400 may also control the reagent needle assembly 710 to the reagent loading station 520 to collect and store a portion of the sample before controlling the reagent needle assembly 710 to the reagent storage mechanism 600 to collect the first reagent.
In other embodiments, the controller 400 controls the reagent needle assembly 710 to collect a portion of the sample and the first reagent and controls the reaction mechanism 500 to rotate to the reagent adding station 520 loaded with an empty reaction vessel, and the controlling the reagent needle assembly 710 to add the portion of the sample and the first reagent to the empty reaction vessel 510 may include:
the controller 400 controls the reagent needle assembly 710 to reach the reagent storage mechanism 600 to collect the first reagent, controls the reagent needle assembly 710 to add the first reagent to the empty reaction vessel 510, then the controller 400 controls the reagent needle assembly 710 to reach the reagent adding station 520 to collect a part of the sample, and controls the reagent needle assembly 710 to add a part of the sample to the reaction vessel 510 filled with the first reagent, so that the amount of the sample or the first reagent collected by the reagent needle assembly 710 can be more accurate without mutual influence and the detection accuracy can be improved by collecting the sample and the first reagent respectively.
In other embodiments, the controller 400 may also control the reagent needle assembly 710 to the reagent adding station 520 to collect a partial sample and control the reagent needle assembly 710 to add a partial sample to the empty reaction vessel 510, and then the controller 400 controls the reagent needle assembly 710 to the reagent storage mechanism 600 to collect the first reagent and controls the reagent needle assembly 710 to add the first reagent to the reaction vessel 510 containing a partial sample.
In this embodiment, the sample analyzer 10 may further include a stirring rod 730 disposed adjacent to the reaction mechanism 500, and the controller 400 is further configured to control the stirring rod 730 to stir and mix the sample in the reaction container 510 located in the reagent adding station 520 before the reaction container 510 receives the first reagent and/or after the reaction container receives the second reagent, so that the sample and the reagent can be sufficiently mixed, and the detection accuracy can be improved.
In this embodiment, the sample analyzer 10 may further include a first washing mechanism 740, the first washing mechanism 740 is disposed on a movement track of the reagent needle assembly 710, and the controller 400 is configured to control the reagent needle assembly 710 to move to the first washing mechanism 740 for washing, so as to prevent the reagent needle assembly 710 from contaminating a sample or a reagent in a subsequent process. It is understood that the first cleaning mechanism may be various, such as an ultrasonic cleaning tank or a vortex cleaning tank, and the like, and is not limited herein.
In this embodiment, the sample analyzer 10 may further include a second cleaning mechanism (not shown), the second cleaning mechanism is disposed on the circumference of the reaction mechanism 500, and the controller 400 is configured to control the second cleaning mechanism to clean the reaction container 510 loaded with the sample and having the sample detected, so that the reaction container 510 can receive the next sample or reagent conveniently, the reaction container 510 does not need to be taken out for cleaning or discarding, the operation process is simplified, and the consumable utilization efficiency is improved.
In this embodiment, the sample analyzer 10 can further include a wash station 540, the reagent loading station 520 being located opposite the detection station 530, and the sample loading station 220 and the wash station 540 being spaced apart from the reagent loading station 520 by the detection station 530.
In this embodiment, after the sample of the reaction vessel 510 is detected for the second time, the sample is moved to the cleaning station 540, and the cleaning station 540 is used to draw out the sample in the reaction vessel 510, and sequentially inject and draw out the diluent, the cleaning solution, and the diluent, so as to clean the reaction vessel 510 and avoid contamination of the next sample.
In this embodiment, the sample analyzer 10 may further include a third cleaning mechanism 750, the third cleaning mechanism 750 is disposed on the movement track of the stirring rod 730, and the controller 400 is configured to control the stirring rod 730 to move to the third cleaning mechanism 750 for cleaning, so as to prevent the stirring rod 730 from contaminating the sample or the reagent in the subsequent process. It is understood that the third cleaning mechanism may also be diversified, such as being designed as an ultrasonic cleaning tank or a vortex cleaning tank, and the like, and is not limited herein.
In this embodiment, the controller 400 is further configured to control the gripping member 320 of the transportation mechanism 300 or the sampling mechanism 200 to transport the test tube 20 loaded with the sample after the sampling is completed out of the sample analyzer 20, so as to recycle or dispose of the test tube 20.
In this embodiment, the sampling mechanism 200 includes a sampling station 210, and the sampling mechanism 200 is configured to sample a sample at the sampling station 210, where a time period from a current sample being added to the sample adding station 220 to a next sample being added to the sample adding station 220 is one cycle; and/or the sample is transported from outside the housing 101 to the sampling station 210 for a period; and/or the time from the time when the sample is transported to the sampling station 210 to the time when the sample is added at the sample adding station 220 is counted as a cycle, the controller 400 can control the plurality of samples to simultaneously start the steps of mixing, sampling, detecting and the like, so that the operations of mixing, sampling, detecting and the like can be simultaneously performed, the mixing, sampling and detecting can be simultaneously finished, the next process can be simultaneously started, the waiting time is not needed among the steps, and the detection efficiency can be further improved.
Referring to fig. 7, an embodiment of a detection method of the sample analyzer of the present invention includes:
and S11O, controlling the reaction mechanism to rotate so as to transport the reaction container in the reaction mechanism to the sample adding station to receive the sample.
And S120, controlling the reaction mechanism to rotate to transport the reaction container to a reagent adding station to receive the reagent collected by the reagent needle assembly from the reagent storage mechanism.
S130, controlling the reaction mechanism to rotate so as to transport the reaction container to the detection station to detect the sample once through the detection mechanism, wherein when the previous sample is transported to the detection station to be detected once, the current sample is transported to the reagent adding station.
The specific detection method in this embodiment refers to the sample analyzer embodiment described above, and is not described herein again, and this embodiment enables two samples to simultaneously implement different operations in the reaction mechanism, thereby reducing the detection time and improving the detection efficiency.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes performed by the present specification and drawings, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.

Claims (16)

1. A sample analyzer, comprising:
the reaction mechanism is provided with a plurality of container positions, the container positions are used for bearing reaction containers, the reaction containers are used for loading samples, and the reaction mechanism is respectively provided with a sample adding station, a reagent adding station and a detection station along the circumferential direction of the reaction mechanism;
the reagent storage mechanism is arranged adjacent to the reaction mechanism and is used for bearing a reagent container filled with a reagent;
a reagent needle assembly disposed adjacent to the reaction mechanism and the reagent storage mechanism for collecting the reagent in the reagent container and adding the reagent to the reaction container;
a detection mechanism disposed adjacent to the reaction mechanism;
and the controller is used for controlling the reaction mechanism to rotate so as to transport the reaction container to the sample adding station to receive the sample, to the reagent adding station to receive the reagent and to the detection station to detect the sample for one time, wherein when the previous sample is transported to the detection station to detect for one time, the current sample is transported to the reagent adding station.
2. The sample analyzer of claim 1, wherein the reagent station is disposed adjacent to the reagent storage mechanism in a circumferential direction of the reaction mechanism, and the detection station is disposed at a position opposite to the reagent station.
3. The sample analyzer of claim 2, wherein the container positions are sequentially and incrementally labeled as container positions along the circumferential direction of the reaction mechanism, the difference between two adjacent container positions is 1, and the difference between the container position of the previous sample and the container position of the current sample is half of the total container position.
4. The sample analyzer of claim 3, wherein the reaction vessels sequentially transported to the testing station for testing are not adjacent in vessel number.
5. The sample analyzer of claim 1, wherein the controller is further configured to control the reaction mechanism to rotate to transport the sample that has undergone one test to the testing station after the sample arrives at the reagent adding station and before the sample arrives at the testing station for one test, so as to perform a second test on the sample that has undergone one test.
6. The sample analyzer of claim 5 wherein the time from the current addition of the sample to the sample application station to the next addition of the sample to the sample application station is counted as one cycle, and the time from the one detection of the second detection interval is at least six cycles.
7. The sample analyzer of claim 1 wherein the reagents include a first reagent and a second reagent, and the controller is configured to control the reaction mechanism to rotate after the reaction vessel receives the sample such that the reaction vessel reaches the reagent processing station to receive the first reagent and the second reagent.
8. The sample analyzer of claim 7 wherein the controller controls the reaction mechanism to rotate such that the reaction vessel reaches the reagent station to receive the first reagent and the second reagent comprises:
the controller controls the reagent needle assembly to collect a portion of the sample and the first reagent and controls the reaction mechanism to rotate to the reagent adding station loaded with an empty reaction vessel, controls the reagent needle assembly to add the portion of the sample and the first reagent to the empty reaction vessel, and controls the reagent needle assembly to add a second reagent to the reaction vessel to mix with the sample and the first reagent.
9. The sample analyzer of claim 8 wherein the controller controlling the reagent needle assembly to collect a portion of the specimen and the first reagent comprises:
the controller controls the reagent needle assembly to the reagent storage mechanism to collect and store the first reagent and then controls the reagent needle assembly to the reagent adding station to collect a portion of the sample; or
The controller controls the reagent needle assembly to the reagent station to collect and store a portion of the sample, and then controls the reagent needle assembly to the reagent storage mechanism to collect the first reagent.
10. The sample analyzer of claim 8 wherein the controller controls the reagent needle assembly to collect a portion of the specimen and the first reagent and controls the reaction mechanism to rotate to the reagent loading station loaded with an empty reaction vessel, the controlling the reagent needle assembly to add the portion of the specimen and the first reagent to the empty reaction vessel comprising:
said controller controlling said reagent needle assembly to reach said reagent storage mechanism to collect said first reagent and controlling said reagent needle assembly to add said first reagent to said empty reaction vessel, said controller then controlling said reagent needle assembly to reach said reagent adding station to collect a portion of said sample and controlling said reagent needle assembly to add a portion of said sample to a reaction vessel containing said first reagent; or
The controller controls the reagent needle assembly to the reagent station to collect a portion of the sample and controls the reagent needle assembly to add a portion of the sample to the empty reaction vessel, and then the controller controls the reagent needle assembly to the reagent storage mechanism to collect the first reagent and controls the reagent needle assembly to add the first reagent to the reaction vessel containing a portion of the sample.
11. The sample analyzer of claim 7, further comprising a stirring rod disposed adjacent to the reaction mechanism, wherein the controller is further configured to control the stirring rod to stir and mix the sample in the reaction container at the reagent adding station before the reaction container receives the first reagent and/or after the reaction container receives the second reagent.
12. The sample analyzer of claim 1 further comprising a first purge mechanism disposed on a motion trajectory of the reagent needle assembly, the controller for controlling the reagent needle assembly to move to the first purge mechanism for purging; and/or
The sample analyzer further comprises a second cleaning mechanism, the second cleaning mechanism is arranged on the periphery of the reaction mechanism, and the controller is used for controlling the second cleaning mechanism to clean the reaction container which is loaded with the sample and the sample is detected; and/or
The sample analyzer also includes a wash station, the loading station being located opposite the detection station, the loading station and the wash station being spaced apart from the loading station by the detection station.
13. The sample analyzer of claim 11, further comprising a third cleaning mechanism disposed on the motion path of the stirring rod, wherein the controller is configured to control the stirring rod to move to the third cleaning mechanism for cleaning.
14. The sample analyzer of claim 1, further comprising:
the controller is also used for controlling the blending mechanism to blend the sample before the sample reaches the reaction mechanism; and/or
The controller is also used for controlling the sampling mechanism to sample the sample and transport the collected sample to the reaction container of the sample adding station, and the controller is also used for controlling the sampling mechanism to convey the test tube loaded with the sample after the sampling is finished out of the sample analyzer.
15. The sample analyzer of claim 14, further comprising a housing, wherein the intermixing mechanism and the sampling mechanism are disposed within the housing, wherein the sampling mechanism comprises a sampling station, wherein the sampling mechanism is configured to sample the sample at the sampling station, and wherein a period of time is counted from a current time the sample is added to the sample application station to a time a next time the sample is added to the sample application station; and/or the time that the sample is transported from outside the housing to the sampling station is counted as a cycle; and/or the time from the sample being transported to the sampling station to the sample application being completed at the sample application station is counted as a cycle.
16. A method of testing a sample analyzer, comprising:
controlling a reaction mechanism to rotate so as to transport a reaction container in the reaction mechanism to a sample adding station to receive a sample;
controlling the reaction mechanism to rotate to transport the reaction container to a reagent adding station to receive a reagent collected by a reagent needle assembly from a reagent storage mechanism;
controlling the reaction mechanism to rotate so as to transport the reaction container to a detection station to perform primary detection on the sample through the detection mechanism;
and when the previous sample is transported to the detection station for primary detection, the current sample is transported to the reagent adding station.
CN202210019162.4A 2021-06-30 2022-01-06 Sample analyzer and detection method thereof Pending CN115541905A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2021107369619 2021-06-30
CN202110736961 2021-06-30

Publications (1)

Publication Number Publication Date
CN115541905A true CN115541905A (en) 2022-12-30

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Application Number Title Priority Date Filing Date
CN202210019162.4A Pending CN115541905A (en) 2021-06-30 2022-01-06 Sample analyzer and detection method thereof

Country Status (1)

Country Link
CN (1) CN115541905A (en)

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