CN115487097A - Bath explosive salt composition with itching relieving and inflammation diminishing effects and preparation method thereof - Google Patents
Bath explosive salt composition with itching relieving and inflammation diminishing effects and preparation method thereof Download PDFInfo
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- CN115487097A CN115487097A CN202211215387.3A CN202211215387A CN115487097A CN 115487097 A CN115487097 A CN 115487097A CN 202211215387 A CN202211215387 A CN 202211215387A CN 115487097 A CN115487097 A CN 115487097A
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- Prior art keywords
- essential oil
- bath
- salt
- microcapsule
- inflammation
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- 150000003839 salts Chemical class 0.000 title claims abstract description 83
- 239000000203 mixture Substances 0.000 title claims abstract description 69
- 206010061218 Inflammation Diseases 0.000 title claims abstract description 62
- 208000003251 Pruritus Diseases 0.000 title claims abstract description 62
- 230000004054 inflammatory process Effects 0.000 title claims abstract description 60
- 230000007803 itching Effects 0.000 title claims abstract description 58
- 230000003467 diminishing effect Effects 0.000 title claims abstract description 56
- 239000002360 explosive Substances 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000000341 volatile oil Substances 0.000 claims abstract description 75
- 239000003094 microcapsule Substances 0.000 claims abstract description 46
- 239000002131 composite material Substances 0.000 claims abstract description 32
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 24
- 239000000126 substance Substances 0.000 claims abstract description 22
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 17
- 230000002378 acidificating effect Effects 0.000 claims abstract description 15
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims abstract description 12
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 12
- 230000000694 effects Effects 0.000 claims abstract description 12
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 12
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 12
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000003880 Calendula Nutrition 0.000 claims abstract description 9
- 235000007516 Chrysanthemum Nutrition 0.000 claims abstract description 9
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims abstract description 7
- 229910052938 sodium sulfate Inorganic materials 0.000 claims abstract description 7
- 235000011152 sodium sulphate Nutrition 0.000 claims abstract description 7
- 240000001432 Calendula officinalis Species 0.000 claims abstract 3
- 238000003756 stirring Methods 0.000 claims description 35
- 238000005422 blasting Methods 0.000 claims description 20
- 238000002156 mixing Methods 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 239000004094 surface-active agent Substances 0.000 claims description 15
- 150000001875 compounds Chemical class 0.000 claims description 11
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 239000000839 emulsion Substances 0.000 claims description 10
- 238000000227 grinding Methods 0.000 claims description 10
- 239000003921 oil Substances 0.000 claims description 10
- 229940057950 sodium laureth sulfate Drugs 0.000 claims description 10
- SXHLENDCVBIJFO-UHFFFAOYSA-M sodium;2-[2-(2-dodecoxyethoxy)ethoxy]ethyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOCCOCCOCCOS([O-])(=O)=O SXHLENDCVBIJFO-UHFFFAOYSA-M 0.000 claims description 10
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 239000005913 Maltodextrin Substances 0.000 claims description 6
- 229920002774 Maltodextrin Polymers 0.000 claims description 6
- 229940035034 maltodextrin Drugs 0.000 claims description 6
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 claims description 5
- 244000215068 Acacia senegal Species 0.000 claims description 5
- 229920000084 Gum arabic Polymers 0.000 claims description 5
- 239000000205 acacia gum Substances 0.000 claims description 5
- 235000010489 acacia gum Nutrition 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 239000011812 mixed powder Substances 0.000 claims description 5
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims description 5
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims description 5
- 239000011780 sodium chloride Substances 0.000 claims description 5
- 229940035044 sorbitan monolaurate Drugs 0.000 claims description 5
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 4
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 3
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 3
- 230000001139 anti-pruritic effect Effects 0.000 claims description 3
- 239000003908 antipruritic agent Substances 0.000 claims description 3
- 235000015165 citric acid Nutrition 0.000 claims description 3
- 235000011090 malic acid Nutrition 0.000 claims description 3
- 239000001630 malic acid Substances 0.000 claims description 3
- 229920000847 nonoxynol Polymers 0.000 claims description 3
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical class CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 235000002906 tartaric acid Nutrition 0.000 claims description 3
- 239000011975 tartaric acid Substances 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- 229920005682 EO-PO block copolymer Polymers 0.000 claims description 2
- 240000001238 Gaultheria procumbens Species 0.000 claims description 2
- 235000007297 Gaultheria procumbens Nutrition 0.000 claims description 2
- 150000001298 alcohols Chemical class 0.000 claims description 2
- 150000002170 ethers Chemical class 0.000 claims description 2
- 239000001530 fumaric acid Substances 0.000 claims description 2
- 235000011087 fumaric acid Nutrition 0.000 claims description 2
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 2
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims 1
- 241000723353 Chrysanthemum Species 0.000 abstract description 8
- 235000003332 Ilex aquifolium Nutrition 0.000 abstract description 7
- 235000002296 Ilex sandwicensis Nutrition 0.000 abstract description 7
- 235000002294 Ilex volkensiana Nutrition 0.000 abstract description 7
- 241000196324 Embryophyta Species 0.000 abstract description 5
- 239000003205 fragrance Substances 0.000 abstract description 5
- 238000005187 foaming Methods 0.000 abstract description 3
- 241000255925 Diptera Species 0.000 abstract description 2
- SFNALCNOMXIBKG-UHFFFAOYSA-N ethylene glycol monododecyl ether Chemical compound CCCCCCCCCCCCOCCO SFNALCNOMXIBKG-UHFFFAOYSA-N 0.000 abstract description 2
- 230000002045 lasting effect Effects 0.000 abstract description 2
- 238000012423 maintenance Methods 0.000 abstract description 2
- 230000001846 repelling effect Effects 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 241000132025 Calendula Species 0.000 description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L magnesium sulphate Substances [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 6
- 235000019341 magnesium sulphate Nutrition 0.000 description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- 239000006260 foam Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 238000004880 explosion Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 210000005036 nerve Anatomy 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000003287 bathing Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- DUIOKRXOKLLURE-UHFFFAOYSA-N 2-octylphenol Chemical class CCCCCCCCC1=CC=CC=C1O DUIOKRXOKLLURE-UHFFFAOYSA-N 0.000 description 1
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 206010033733 Papule Diseases 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 229940061720 alpha hydroxy acid Drugs 0.000 description 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000011837 pasties Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 210000000106 sweat gland Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/11—Encapsulated compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
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- A61P17/04—Antipruritics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a bath explosive salt composition with itching relieving and inflammation diminishing effects and a preparation method thereof, belonging to the technical field of explosive salts and preparation methods thereof, and comprising an acidic substance, sodium bicarbonate, a nonionic surfactant, a silicon dioxide anticaking agent, laureth sodium sulfate, salt and composite essential oil microcapsules, wherein the composition is long in foaming maintenance time (generally about 10 min) when in use, and the composition formula also contains the composite essential oil microcapsules, so that the composition can be slowly released when in use, and has lasting fragrance and effect. The composite essential oil in the composite essential oil microcapsule is prepared from chrysanthemum essential oil, calendula essential oil and holly essential oil according to a mass ratio of 1:1:1, the three plant essential oils have synergistic effect, can well play roles of bacteriostasis, itching relieving and inflammation diminishing, and the chrysanthemum essential oil, the calendula essential oil and the holly essential oil have pleasant smell and good mosquito repelling effect.
Description
Technical Field
The invention relates to the technical field of explosive salt and a preparation method thereof, in particular to a bath explosive salt composition with itching relieving and inflammation diminishing effects and a preparation method thereof.
Background
With the improvement of living standard and consumption standard, people pay more and more attention to health care, wherein skin care is paid more and more attention to numerous people, especially women. The salt has long been recognized for the specific efficacy of skin health care, and not only has the effects of sterilizing and diminishing inflammation, expelling toxin and deodorizing, and relaxing channels and promoting blood circulation, but also has the effects of deeply cleaning skin, smoothening skin unevenness, improving rough skin, astringing sebaceous glands, removing redundant grease, losing weight and shaping body. However, most of the common bath salt products in the market at present are solid loose salt or single pasty bath salt, the solid loose salt is easy to run off when in use, which causes waste, and if the salt is simply mixed with other auxiliary materials, the product has relatively single function, and cannot achieve ideal bath effect; meanwhile, due to the fact that the salt particles are large in size, the skin is easily scratched when the salt particles are rubbed with the skin, and the application and popularization of the bath salt are severely limited.
Explosive salt (also called bath salt) is put into bath water during bathing, a large amount of bubbles are generated within a certain time, so that the bath salt not only has visual enjoyment, but also has certain impact on the skin to play a role in massaging, and people feel comfortable and pleasant during bathing, and therefore, the bath salt is more and more popular with consumers.
The hot, humid summer and dry autumn and winter are periods of high incidence of skin disease. In summer, due to the fact that in a high-temperature muggy environment, various germs are easily infected when skin sweats, sweat glands are blocked due to evaporation of the sweat, and papules, blisters and the like are formed; the skin is easy to dry in the seasons of frequent air conditioning and autumn and winter, the skin is easy to be damaged and infected after scratching, and no matter which part of the body suffers from skin inflammation or eczema, the patient can suffer from huge pain due to strong itch, and the normal life and work are seriously affected.
Chinese patent CN202110976425.6 discloses a shapeable explosive salt, which comprises sodium bicarbonate 3040%, alpha hydroxy acid 1030%, light sodium carbonate or tower powder or a mixture of light sodium carbonate and tower powder 10% 15%, emulsifier 0.1%, maltodextrin 10% 15%, soluble corn starch 6%, polyethylene glycol 1% 5%. The explosive salt of the technology generates a large amount of bubbles when meeting water, and has the advantages of long foaming time, good foam performance, rich and fine foam, good foam stability and strong foam liquid-carrying capacity. The skin feel is good, and the skin is moist, smooth, not dry and not tight after being used, but can not be used for relieving the symptoms of pruritus and inflammation of the human body.
Disclosure of Invention
The embodiment of the invention provides a bath explosive salt composition with itching relieving and inflammation diminishing effects and a preparation method thereof, which are used for relieving pain parts of human body itching and inflammation during bath and comprise the following contents:
the first purpose of the invention is to provide a bath blasting salt composition with itching relieving and inflammation diminishing effects, which is technically characterized by comprising 20-35 parts by weight of acidic substances, 30-40 parts by weight of sodium bicarbonate, 20-30 parts by weight of nonionic surfactant, 6-8 parts by weight of silicon dioxide anticaking agent, 3-4 parts by weight of sodium laureth sulfate, 20-30 parts by weight of salt and 6-9 parts by weight of composite essential oil microcapsules.
In some embodiments of the present invention, the acidic substance in the bath blasting salt composition with itching relieving and inflammation diminishing effects is at least one of citric acid, tartaric acid, malic acid and fumaric acid.
In some embodiments of the present invention, the nonionic surfactant in the bath blasting salt composition with antipruritic and anti-inflammatory effects is selected from ethoxylated octyl phenol, ethoxylated nonyl phenol, and ethoxylated straight chain C 8-22 Alcohol, propoxylated straight chain C 8-22 Alcohol, ethoxylated and propoxylated straight chain C 8-22 Alcohols, polyethylene glycol ethers of sorbitol, ethylene oxide-propylene oxide block copolymers, and mixtures thereof.
In some embodiments of the present invention, the salt in the bath blasting salt composition with itching relieving and inflammation diminishing effects is any one of sodium sulfate and sodium chloride.
In some embodiments of the present invention, the preparation process of the composite essential oil microcapsule in the bath blasting salt composition with itching relieving and inflammation diminishing effects comprises: mixing gum arabic, maltodextrin and water according to the proportion of 1: (1-3): (20-60), and stirring at 50-70 ℃ for 4-6h to obtain microcapsule wall material aqueous solution; mixing compound essential oil, a surfactant and sodium dodecyl sulfate, wherein the mass ratio of the compound essential oil to the surfactant to the sodium dodecyl sulfate is (10-16): (0.2-0.6): (0.2-0.4), stirring for 2-5h at 40-60 ℃, and homogenizing under high pressure for 2-6min to obtain microcapsule oil core water emulsion; mixing the microcapsule wall material aqueous solution and the microcapsule oil core aqueous emulsion according to the proportion of 1: (0.1-0.3), homogenizing under high pressure for 2-6min, stirring at 40-60 deg.C for 2-7h, and cooling to 20-30 deg.C to obtain composite essential oil microcapsule.
In some embodiments of the present invention, in the bath blasting salt composition with itching relieving and inflammation diminishing effects, the surfactant is at least one of sorbitan monolaurate and polyoxyethylene sorbitan monostearate.
In some embodiments of the present invention, the composite essential oil in the bath explosive salt composition with itching relieving and inflammation diminishing effects is prepared from chrysanthemum essential oil, calendula essential oil and wintergreen essential oil in a mass ratio of 1:1:1 are mixed.
The second purpose of the invention is to provide a preparation method of bath explosive salt with itching relieving and inflammation diminishing effects, which is technically characterized by comprising the following steps:
respectively grinding sodium bicarbonate, an acidic substance and a silicon dioxide anticaking agent by using grinding equipment to obtain uniform powder for later use;
step two, adding the composite essential oil microcapsule into the mixed powder in the step one, and uniformly stirring for later use;
step three, uniformly stirring the nonionic surfactant, the sodium laureth sulfate and the salt, then pouring the mixture and the substances obtained in the step two into a stirring device, and fully stirring the mixture until the mixture is uniformly mixed for later use;
and step four, adding the mixed base material into a proper mould, and forming under high pressure to obtain the bath explosive salt with the itching relieving and inflammation diminishing effects.
Compared with the prior art, the bath explosive salt composition with the itching relieving and inflammation diminishing effects and the preparation method thereof have the following beneficial effects:
1. the bath blasting salt composition with the itching relieving and inflammation diminishing effects comprises an acidic substance, sodium bicarbonate, a nonionic surfactant, a silicon dioxide anticaking agent, laureth sodium sulfate, salt and composite essential oil microcapsules, wherein the composition is long in foaming maintenance time (generally about 10 min) when in use, and the composite essential oil microcapsules are contained in the formula of the composition, so that the composition can be slowly released when in use, and the fragrance and the effect are lasting.
2. The composite essential oil in the composite essential oil microcapsule of the bath explosive salt composition with the functions of relieving itching and diminishing inflammation is prepared from chrysanthemum essential oil, calendula essential oil and holly essential oil in a mass ratio of 1:1:1, the three plant essential oils have synergistic effect, can well play roles of bacteriostasis, itching relieving and inflammation diminishing, and the chrysanthemum essential oil, the calendula essential oil and the holly essential oil have pleasant smell and good mosquito repelling effect.
3. The bath explosive salt prepared by the preparation method of the bath explosive salt with itching relieving and inflammation diminishing effects has complete appearance, is not easy to break in the transportation process, but is dissolved when meeting water, and is suitable for industrial large-scale production.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the technical solutions of the present invention will be clearly and completely described below with reference to the specific embodiments of the present invention. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A bath explosive salt composition with itching relieving and inflammation relieving effects comprises 27.5kg of acidic substance, 35kg of sodium bicarbonate, 25kg of nonionic surfactant, 7kg of silicon dioxide anticaking agent, 3.5kg of sodium laureth sulfate, 25kg of salt and 7.5kg of composite essential oil microcapsule.
Preferably, the acidic substance in the bath explosive salt composition with itching relieving and inflammation diminishing effects is citric acid.
Preferably, the nonionic surfactant in the bath explosive salt composition with itching relieving and inflammation diminishing effects is ethoxylated octylphenol.
Preferably, the bath blasting salt composition with itching relieving and inflammation diminishing effects is sodium sulfate.
Preferably, the preparation process of the composite essential oil microcapsule in the bath explosive salt composition with the itching relieving and inflammation diminishing effects comprises the following steps: mixing gum arabic, maltodextrin and water according to the proportion of 1:2:40, stirring for 5 hours at 60 ℃ to obtain microcapsule wall material aqueous solution; mixing compound essential oil, a surfactant and sodium dodecyl sulfate, wherein the mass ratio of the compound essential oil to the surfactant to the sodium dodecyl sulfate is 13:0.4:0.3, stirring for 2-5h at 50 ℃, and homogenizing for 4min under high pressure to obtain microcapsule oil core water emulsion; mixing the microcapsule wall material aqueous solution and the microcapsule oil core aqueous emulsion according to the weight ratio of 1: mixing at a mass ratio of 0.2, homogenizing under high pressure for 4min, stirring at 50 deg.C for 4.5h, and cooling to 25 deg.C to obtain composite essential oil microcapsule.
Preferably, the surfactant in the bath explosive salt composition with itching relieving and inflammation diminishing effects is sorbitan monolaurate.
Preferably, the composite essential oil in the bath blasting salt composition with itching relieving and inflammation diminishing effects is prepared from chrysanthemum essential oil, calendula essential oil and holly essential oil in a mass ratio of 1:1:1 are mixed.
According to the formula, the preparation method of the bath explosion salt with itching relieving and inflammation diminishing effects comprises the following steps:
step one, grinding sodium bicarbonate, an acidic substance and a silicon dioxide anticaking agent into uniform powder for later use by using grinding equipment respectively;
step two, adding the composite essential oil microcapsule into the mixed powder in the step one, and uniformly stirring for later use;
step three, uniformly stirring the nonionic surfactant, the sodium laureth sulfate and the salt, then pouring the mixture and the substances obtained in the step two into a stirring device, and fully stirring the mixture until the mixture is uniformly mixed for later use;
and step four, adding the mixed base material into a proper mould, and forming under high pressure to obtain the bath explosive salt with the itching relieving and inflammation diminishing effects.
The bath explosive salt with the functions of relieving itching and diminishing inflammation is mainly spherical in appearance, and the weight is 50-300 g. When in use, the product can be directly put into warm water of a bathtub, can instantly generate a proper amount of bubbles, can be maintained for a long time (more than 10 min), and can emit natural plant essential oil fragrance, so that a user can achieve the effects of relieving nerves, eliminating fatigue, inhibiting bacteria, relieving itching and diminishing inflammation. The product of the invention can be made into other shapes besides the spherical shape so as to meet the requirements of different users.
Example 2
A bath explosive salt composition with antipruritic and anti-inflammatory effects comprises 20kg of acidic substance, 30kg of sodium bicarbonate, 20kg of nonionic surfactant, 6kg of silicon dioxide anticaking agent, 3kg of sodium laureth sulfate, 20kg of salt and 6kg of composite essential oil microcapsule.
Preferably, the acid substance in the bath explosive salt composition with itching relieving and inflammation diminishing effects is tartaric acid.
Preferably, the nonionic surfactant in the bath explosive salt composition with itching relieving and inflammation diminishing effects is ethoxylated nonyl phenol.
Preferably, the bath explosive salt composition with itching relieving and inflammation diminishing effects is sodium chloride.
Preferably, the preparation process of the composite essential oil microcapsule in the bath blasting salt composition with itching relieving and inflammation diminishing effects comprises the following steps: mixing gum arabic, maltodextrin and water according to the proportion of 1:1:20, and stirring at 50 ℃ for 4 hours to obtain microcapsule wall material aqueous solution; mixing compound essential oil, a surfactant and sodium dodecyl sulfate, wherein the mass ratio of the compound essential oil to the surfactant to the sodium dodecyl sulfate is 10:0.2:0.2, stirring for 2 hours at 40 ℃, and homogenizing for 2min under high pressure to obtain microcapsule oil core water emulsion; mixing the microcapsule wall material aqueous solution and the microcapsule oil core aqueous emulsion according to the weight ratio of 1: mixing at a mass ratio of 0.1, homogenizing under high pressure for 2min, stirring at 40 deg.C for 2 hr, and cooling to 20 deg.C to obtain composite essential oil microcapsule.
Preferably, the surfactant in the bath explosive salt composition with itching relieving and inflammation diminishing effects is polyoxyethylene sorbitan monostearate.
Preferably, the composite essential oil in the bath blasting salt composition with itching relieving and inflammation diminishing effects is prepared from chrysanthemum essential oil, calendula essential oil and holly essential oil in a mass ratio of 1:1:1 are mixed.
According to the formula, the preparation method of the bath explosion salt with itching relieving and inflammation diminishing effects comprises the following steps:
respectively grinding sodium bicarbonate, an acidic substance and a silicon dioxide anticaking agent by using grinding equipment to obtain uniform powder for later use;
step two, adding the composite essential oil microcapsule into the mixed powder in the step one, and uniformly stirring for later use;
step three, uniformly stirring the nonionic surfactant, the sodium laureth sulfate and the salt, then pouring the mixture and the substances obtained in the step two into a stirring device, and fully stirring the mixture until the mixture is uniformly mixed for later use;
and step four, adding the mixed base material into a proper mould, and forming under high pressure to obtain the bath explosive salt with the itching relieving and inflammation diminishing effects.
The bath explosive salt with the functions of relieving itching and diminishing inflammation is mainly spherical in appearance, and the weight is 50-300 g. When in use, the product can be directly put into warm water of a bathtub, can instantly generate a proper amount of bubbles, can be maintained for a long time (more than 10 min), and can emit natural plant essential oil fragrance, so that a user can achieve the effects of relieving nerves, eliminating fatigue, inhibiting bacteria, relieving itching and diminishing inflammation. The product of the invention can be made into other shapes besides the spherical shape so as to meet the requirements of different users.
Example 3
A bath explosive salt composition with itching relieving and inflammation relieving effects comprises 35kg of acidic substance, 40kg of sodium bicarbonate, 30kg of nonionic surfactant, 8kg of silicon dioxide anticaking agent, 4kg of sodium laureth sulfate, 30kg of salt and 9kg of composite essential oil microcapsule.
Preferably, the acid substance in the bath explosive salt composition with itching relieving and inflammation diminishing effects is malic acid.
Preferably, the nonionic surfactant in the bath explosive salt composition with itching relieving and inflammation diminishing effects is ethoxylated straight chain C 8-22 An alcohol.
Preferably, the bath blasting salt composition with the itching relieving and inflammation diminishing effects is a mixture of sodium sulfate and sodium chloride, wherein the weight ratio of the sodium sulfate to the sodium chloride is 1.
Preferably, the preparation process of the composite essential oil microcapsule in the bath blasting salt composition with itching relieving and inflammation diminishing effects comprises the following steps: mixing gum arabic, maltodextrin and water according to the proportion of 1:3:60, stirring for 6 hours at 70 ℃ to obtain microcapsule wall material aqueous solution; mixing compound essential oil, a surfactant and sodium dodecyl sulfate, wherein the mass ratio of the compound essential oil to the surfactant to the sodium dodecyl sulfate is 16:0.6:0.4, stirring for 5 hours at 60 ℃, and homogenizing for 6 minutes under high pressure to obtain microcapsule oil core water emulsion; mixing the microcapsule wall material aqueous solution and the microcapsule oil core aqueous emulsion according to the weight ratio of 1: mixing at a mass ratio of 0.3, homogenizing under high pressure for 6min, stirring at 60 deg.C for 7 hr, and cooling to 30 deg.C to obtain composite essential oil microcapsule.
Preferably, in the bath explosive salt composition with itching relieving and inflammation diminishing effects, the surfactant is a mixture of sorbitan monolaurate and polyoxyethylene sorbitan monostearate, wherein the weight ratio of sorbitan monolaurate to polyoxyethylene sorbitan monostearate is 1.
Preferably, the composite essential oil in the bath blasting salt composition with itching relieving and inflammation diminishing effects is prepared from chrysanthemum essential oil, calendula essential oil and holly essential oil in a mass ratio of 1:1:1 are mixed.
According to the formula, the preparation method of the bath explosion salt with itching relieving and inflammation diminishing effects comprises the following steps:
step one, grinding sodium bicarbonate, an acidic substance and a silicon dioxide anticaking agent into uniform powder for later use by using grinding equipment respectively;
step two, adding the composite essential oil microcapsule into the mixed powder in the step one, and uniformly stirring for later use;
step three, uniformly stirring the nonionic surfactant, the sodium laureth sulfate and the salt, then pouring the mixture and the substances obtained in the step two into a stirring device, and fully stirring the mixture until the mixture is uniformly mixed for later use;
and step four, adding the mixed base material into a proper mould, and forming under high pressure to obtain the bath explosive salt with the itching relieving and inflammation diminishing effects.
The bath explosive salt with the functions of relieving itching and diminishing inflammation is mainly spherical in appearance, and the weight is 50-300 g. When in use, the product can be directly put into warm water of a bathtub, can instantly generate a proper amount of bubbles, can be maintained for a long time (more than 10 min), and can emit natural plant essential oil fragrance, so that a user can achieve the effects of relieving nerves, eliminating fatigue, inhibiting bacteria, relieving itching and diminishing inflammation. The product of the invention can be made into other shapes besides the spherical shape so as to meet the requirements of different users.
The above description is only an example of the present invention, and is not intended to limit the present invention. Various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.
Claims (8)
1. A bath explosive salt composition with itching relieving and inflammation diminishing effects is characterized by comprising, by weight, 20-35 parts of an acidic substance, 30-40 parts of sodium bicarbonate, 20-30 parts of a nonionic surfactant, 6-8 parts of a silicon dioxide anticaking agent, 3-4 parts of sodium laureth sulfate, 20-30 parts of a salt and 6-9 parts of a composite essential oil microcapsule.
2. The bath blasting salt composition with itching relieving and inflammation diminishing effects of claim 1, wherein the acidic substance is at least one of citric acid, tartaric acid, malic acid and fumaric acid.
3. The bath blasting salt composition with antipruritic and anti-inflammatory effects of claim 1, wherein the nonionic surfactant is selected from the group consisting of ethoxylated octylphenol, ethoxylated nonylphenol, and ethoxylated linear C 8-22 Alcohol, propoxylated straight chain C 8-22 Alcohol, alcohol,Ethoxylated and propoxylated straight chain C 8-22 Alcohols, polyethylene glycol ethers of sorbitol, ethylene oxide-propylene oxide block copolymers, and mixtures thereof.
4. The bath blasting salt composition with itching-relieving and inflammation-diminishing effects of claim 1, wherein the salt is any one of sodium sulfate and sodium chloride.
5. The bath blasting salt composition with itching relieving and inflammation diminishing effects of claim 1, wherein the composite essential oil microcapsule is prepared by the following steps: mixing gum arabic, maltodextrin and water according to the proportion of 1: (1-3): (20-60), and stirring at 50-70 ℃ for 4-6h to obtain microcapsule wall material aqueous solution; mixing compound essential oil, a surfactant and sodium dodecyl sulfate, wherein the mass ratio of the compound essential oil to the surfactant to the sodium dodecyl sulfate is (10-16): (0.2-0.6): (0.2-0.4), stirring for 2-5h at 40-60 ℃, and homogenizing for 2-6min under high pressure to obtain microcapsule oil core water emulsion; mixing the microcapsule wall material aqueous solution and the microcapsule oil core aqueous emulsion according to the proportion of 1: (0.1-0.3), homogenizing under high pressure for 2-6min, stirring at 40-60 deg.C for 2-7h, and cooling to 20-30 deg.C to obtain composite essential oil microcapsule.
6. The bath blasting salt composition with itching-relieving and inflammation-diminishing effects according to claim 5, wherein the surfactant is at least one of sorbitan monolaurate and polyoxyethylene sorbitan monostearate.
7. The bath blasting salt composition with itching relieving and inflammation diminishing effects as claimed in claim 5, wherein the compound essential oil is prepared from chrysanthemum essential oil, calendula essential oil and wintergreen essential oil in a mass ratio of 1:1:1 are mixed.
8. A preparation method of bath explosive salt with itching relieving and inflammation diminishing effects is characterized by comprising the following steps:
step one, grinding sodium bicarbonate, an acidic substance and a silicon dioxide anticaking agent into uniform powder for later use by using grinding equipment respectively;
step two, adding the composite essential oil microcapsule into the mixed powder in the step one, and uniformly stirring for later use;
step three, uniformly stirring the nonionic surfactant, the sodium laureth sulfate and the salt, then pouring the mixture and the substances obtained in the step two into a stirring device, and fully stirring the mixture until the mixture is uniformly mixed for later use;
and step four, adding the mixed base material into a proper mould, and forming under high pressure to obtain the bath explosive salt with the itching relieving and inflammation diminishing effects.
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| US6121215A (en) * | 1999-08-27 | 2000-09-19 | Phyzz, Inc. | Foaming effervescent bath product |
| CN102078268A (en) * | 2009-11-30 | 2011-06-01 | 厦门娜其尔日化有限公司 | Explosive salt and preparation method thereof |
| EP2653151A2 (en) * | 2012-04-18 | 2013-10-23 | Merz Pharma GmbH & Co. KGaA | Solid oil salt bath compositions easily to be prepared from 2 phases having an application related flexibility |
| US20180140534A1 (en) * | 2015-04-22 | 2018-05-24 | Cosmetic Warriors Limited | Lathering bathing composition |
| CN111514068A (en) * | 2020-06-08 | 2020-08-11 | 程红梅 | A cosmetic containing natural plant essential oil |
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2022
- 2022-09-30 CN CN202211215387.3A patent/CN115487097A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6121215A (en) * | 1999-08-27 | 2000-09-19 | Phyzz, Inc. | Foaming effervescent bath product |
| CN102078268A (en) * | 2009-11-30 | 2011-06-01 | 厦门娜其尔日化有限公司 | Explosive salt and preparation method thereof |
| EP2653151A2 (en) * | 2012-04-18 | 2013-10-23 | Merz Pharma GmbH & Co. KGaA | Solid oil salt bath compositions easily to be prepared from 2 phases having an application related flexibility |
| US20180140534A1 (en) * | 2015-04-22 | 2018-05-24 | Cosmetic Warriors Limited | Lathering bathing composition |
| CN111514068A (en) * | 2020-06-08 | 2020-08-11 | 程红梅 | A cosmetic containing natural plant essential oil |
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