CN115479928A - LAbview-based synchronous detection control system and control method for low-intensity light signals - Google Patents
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Abstract
The invention discloses a synchronous detection control system and a synchronous detection control method of low-intensity optical signals based on Labview, wherein the control system comprises a low-intensity optical signal generating module, a data acquisition module, a sequence generating module, an image generating module and a Labview control module, wherein the data acquisition module, the sequence generating module and the image generating module are all in communication connection with the Labview control module, the low-intensity optical signal generating module is connected with the data acquisition module, and the sequence generating module acts on the low-intensity optical signal generating module and the data acquisition module, so that weak optical signals with specific counting sampling time can be detected, the problems that a detector does not have logic gate triggering and has harsh triggering conditions or cannot realize long pulse sequence triggering counting are solved, the limitation of the conditions of the detector and a pulse generating instrument can be effectively coped with, and the synchronous detection of the weak optical signals with high precision and high sensitivity is realized.
Description
Technical Field
The invention relates to the technical field of photoluminescence detection, in particular to a synchronous detection control system and a synchronous detection control method of low-intensity light signals based on labview.
Background
Photoluminescence detection is a mode for detecting photoluminescence signals by using a detector with high sensitivity and high time resolution, low-intensity optical signals generated by exciting a sample change along with the frequency change of an excitation wave field, and fluorescent signals of multiple points on the sample can be detected and fluorescent intensity arrangement of corresponding positions can be generated, so that information carried by the sample can play roles in representing and detecting a local magnetic field, addressing defects of the sample and the like, and the photoluminescence detection is widely applied to the fields of quantum detection, quantum communication and the like. The single photon counter is a precise instrument which is used for detecting low-intensity optical signals and has high time resolution, and converts the optical signals into electric signals and rejects the electric signals through a voltage threshold, so that instrument noise caused by an electronic instrument is avoided, and extremely weak signals can be detected.
Because the detection of the low-intensity fluorescent signal needing synchronous time sequence control is inevitably realized by the triggering of a logic gate, the triggering duration needs to be controlled more accurately so as to avoid the time difference between different pulse sequences and further avoid the loss of carried information. However, the mainstream single photon counter in the market at present has the problems that a logic gate trigger module is not provided, the trigger requirement is too strict (for example, dark current with a specific value is required to control in addition to a pulse signal), and the detection of long trigger time cannot be realized due to the limitation of the precision of a sequence generation instrument. These problems lead to a decrease in the detection accuracy of fluorescence, and further to a problem of a decline in the parameter index represented by fluorescence or a loss of the carried information.
Disclosure of Invention
In order to overcome the problems in the prior art, the invention provides a synchronization detection control system and a control method of a low-intensity light signal based on labview.
The technical scheme adopted by the invention for solving the technical problems is as follows: the synchronous detection control system of the low-intensity light signals based on Labview comprises a low-intensity light signal generating module, a data collecting module, a sequence generating module, an image generating module and a Labview control module, wherein the data collecting module, the sequence generating module and the image generating module are all in communication connection with the Labview control module, the low-intensity light signal generating module is connected with the data collecting module, and the sequence generating module acts on the low-intensity light signal generating module and the data collecting module.
According to the synchronous detection control system of the low-intensity optical signal based on Labview, the Labview control module controls the sequence generation module to generate the pulse sequence, the pulse sequence generated by the sequence generation module acts on the low-intensity optical signal generation module and the data acquisition module, the data acquisition module sends acquired data to the Labview control module, the Labview control module sends the data acquired by the data acquisition module to the image generation module, and the image generation module performs image drawing.
According to the labview-based synchronous detection control system for the low-intensity optical signals, the low-intensity optical signal generating module comprises a laser, a dichroic mirror, a filter and an objective lens, the data collecting module comprises a single photon counter and a data collecting card, and the sequence generating module comprises a sequence generator.
The control method of the synchronous detection control system of the low-intensity light signal based on labview comprises the following steps:
step 1, a Labview control module controls a sequence generation module to generate a pulse sequence with a pulse width t to act on a low-intensity light signal generation module, and the low-intensity light signal generation module emits exciting light with duration time equal to the pulse width t;
step 2, the sequence generation module synchronously sends out a second pulse width t at the rising edge of the pulse sequence with the pulse width t 1 The pulse sequence acts on the data acquisition module, and the data acquisition module reads out the number of instantaneous photons as X 1 ；
Step 3, the sequence generation module synchronously sends out a second pulse width t at the falling edge of the pulse sequence with the pulse width t 1 The pulse sequence acts on a data acquisition moduleThe instantaneous photon number of block read is X 2 ；
Step 4, the instantaneous photon number X obtained in the steps 2 and 3 is used 1 、X 2 Sending the data to a Labview control module, and controlling the image generation module to X by the Labview control module 1 、X 2 Performing subtraction to obtain pulse photon counting with single pulse width t;
step 5, repeating the steps 1-4 to obtain photon counting signals for N times;
and 6, drawing a time-photon counting curve through an image generation module according to the N photon technology signals obtained in the step 5.
The control method of the labview-based synchronous detection control system for the low-intensity light signal is characterized in that in the step 1, the process of emitting the excitation light by the low-intensity light signal generation module is as follows: the pulse sequence with the pulse width t generated by the sequence generation module acts on the low-intensity optical signal generation module, so that the low-intensity optical signal generation module emits exciting light with the duration equal to the pulse width t, the exciting light is focused through the dichroic mirror and the objective lens to excite a sample, the number of fluorescence photons generated after the sample is excited is collimated and collected through the objective lens again, and the fluorescence collected by the objective lens passes through the dichroic mirror and then is filtered through the long-pass, band-pass and short-pass filters in sequence.
The invention has the beneficial effects that: (1) A time sequence control mode is provided for a single photon counter without sampling logic gate triggering and harsh triggering conditions: many single photon counters on the market at present do not have a time sequence control function, or need a dark current with a specific numerical value for control except a pulse signal, the single photon counters are enabled to count continuously without performing any time sequence control on the single photon counters, and a counting logic gate of a data acquisition card is controlled, so that the requirement on a sampling logic gate of the counters is avoided by a mode of performing differential counting through multiple times of detection;
(2) The limitation on the precision of the sequence generating device is overcome: the photon counter cannot count pulses for a long time due to the limitation that a part of the sequence generating device cannot output pulse trains with longer pulse widths. The persistence and applicability of timing measurements is greatly limited. Photon counting detection in a longer duration can be realized by a difference mode, and the elbow of a sequence generation module is overcome.
Drawings
The invention is further illustrated by the following examples in conjunction with the drawings.
FIG. 1 is a diagram illustrating the correspondence between modules according to the present invention;
FIG. 2 is a flow chart of a control method of the present invention;
FIG. 3 is a schematic diagram of a single pulse signal of the sequencer module of the present invention;
FIG. 4 is an interface diagram of the test results of the present invention.
Detailed Description
In order to make the technical solutions of the present invention better understood, the present invention will be described in detail below with reference to the accompanying drawings and the detailed description.
The embodiment provides a scheme for acquiring a high-precision and high-sensitivity time sequence signal of a single photon counter which does not have logic gate triggering and has harsh triggering conditions or cannot realize long pulse sequence triggering counting, as shown in fig. 1, a synchronization detection control system of a low-intensity light signal based on Labview comprises a low-intensity light signal generating module, a data acquisition module, a sequence generating module, an image generating module and a Labview control module, wherein the data acquisition module, the sequence generating module and the image generating module are all in communication connection with the Labview control module, the low-intensity light signal generating module is connected with the data acquisition module, and the sequence generating module acts on the low-intensity light signal generating module and the data acquisition module.
The Labview control module controls the sequence generation module to generate a pulse sequence, the pulse sequence generated by the sequence generation module acts on the low-intensity optical signal generation module and the data acquisition module, the data acquisition module sends acquired data to the Labview control module, the Labview control module sends the data acquired by the data acquisition module to the image generation module, and the image generation module performs image drawing.
In this embodiment, the low-intensity optical signal generating module includes a laser, a dichroic mirror, a filter, and an objective lens, the data collecting module includes a single photon counter and a data collecting card, and the sequence generating module includes a sequencer.
As shown in fig. 2, the control method of the labview-based synchronous detection control system for low-intensity light signals comprises the following steps:
s1 Low intensity fluorescence excitation
S1.1, a simpler implementation mode is realized by a confocal system, a Labview control module controls a sequence generation module to generate a pulse sequence with the pulse width t and the high and low levels of +/-5V so as to control the duration time of exciting light, and the pulse width t is selected to be 50us in the embodiment;
532mn exciting light emitted from S1.2 is reflected by a dichroic mirror and focused by a 100X 0.9NA objective lens to excite a sample, the number of fluorescence photons generated after excitation is collimated and collected by the objective lens again, the fluorescence collected by the objective lens is filtered by a dichroic mirror in order to ensure the wavelength accuracy and the power accuracy, and the interference of the exciting light on signals is reduced to the maximum extent, wherein the selection of the dichroic mirror and the filter depends on the wavelength of fluorescence signals.
S2: synchronous collection of excitation light rising edges
S2.1, considering the problem that the back aperture size of a part of objective lens causes larger fluorescent light spots, or a part of single photon counter needs to be transmitted through optical fiber, so that the fluorescence passing through a filter needs to be focused through the objective lens again, in the embodiment, the SPCM-AQRH-16-FC of Excelitas Technologies needs to be coupled into a single mode optical fiber, the step is realized through a 10X 0.3NA objective lens, and the single photon counter receives an optical signal, converts the optical signal into a voltage signal and collects the voltage signal by a data acquisition card;
s2.2 when the collection task is the first photon counting collection, the collection pulse width is high level pulse width, the starting edge is a falling edge, the Labview control module controls the sequence generation and synchronous control module to generate a pulse sequence with the pulse width of 50us to act on the excitation optical logic gate, and the first pulse width t is synchronously sent out at the rising edge of the pulse 1 The pulse of (a) acts on the data acquisition module, t 1 Same as the rising edge of the t pulseAnd the pulse width is less than t, the synchronous acquisition pulse sequence is shown in fig. 3;
S2.3 t 1 the pulse rising edge effect triggers a counting module of the data acquisition card to display the instantaneous photon counting at the moment for the first time, and the reading is X 1 From fig. 4.
S3: synchronous collection of the falling edge of the excitation light
S3.1 when the collection task is the second photon counting collection, the collection pulse width is high level pulse width, the starting edge is a falling edge, and a second pulse width t is synchronously sent out at the falling edge of 50us pulse acting on the low-intensity optical signal generation and collection module 1 The pulse of (a) acts on the data acquisition and storage module, as shown in fig. 3;
S3.2 t 1 the pulse rising edge effect triggers a data acquisition card counting module to carry out secondary display on the instantaneous photon counting at the moment, and the reading is still X 1 From fig. 4.
S4: photon count value processing and readout
S4.1, synchronously reading the photon count displayed after the photon count acts on the acquisition module for the first time, and controlling the single pulse width of the read pulse sequence to be t 1 Showing a reading of X 1 ；
S4.2 exciting the falling edge of the pulse signal to synchronously read the photon count displayed by the acquisition module for the second time, wherein the pulse width is still t 1 The photon counter displays the index X 2 ；
And S4.3, carrying out difference on the data read twice in the process of passing, so as to obtain photon count X2-X1 in the time interval, wherein the data analysis in the figure 4 can obtain the photon count value of 71911cps as the maximum photon count value, 66810cps as the minimum photon count value and 69126cps as the average photon count value.
Here, it should be noted that: the first and second synchronous acquisition readings are continuously accumulated along with the increase of the counting time, and the numerical value is far larger than the single counting, but the single counting result after the difference is made is not influenced. Before the excitation saturation is not reached, the number of the generated fluorescence photons is determined by the number of defects in the sample and the power of the excitation light, and different samples and the same sample with different numbers of defects and different powers of the excitation light can cause larger difference of the number of the fluorescence photons.
Here, it should be noted that: the pulse width t1 of the counting logic gate action of the data acquisition card does not have very definite requirements twice, and only the instantaneous reading when the high level is acted is displayed. The read readings after twice acting on the counting logic gate are displayed through a display control of the Labview control module, so that the fluctuation of data caused by the pulse width can not influence the final result, and the display result is an instantaneous value. However, the pulse width of the pulse signal applied to the excitation optical logic gate and the excitation light power need to be controlled better to avoid higher power noise or incomplete spin polarization, where higher power noise may affect the signal stability and incomplete spin polarization may affect the generation of the number of fluorescence photons.
The steps S1 to S4 are performed to read out the photon count in a single time interval, and in order to better grasp the fluorescence excitation characteristic, the fluorescence signal needs to be read out multiple times and the time-dependent change relationship of the fluorescence power is obtained.
S5: cumulative multiple readout of photon count values
S5.1, controlling a sequence generator to send out a 50us pulse high-level sequence through a Labview control module so as to excite multiple light pulses. At the same time, the control sequencer sends out t at the rising and falling edges of the excitation light pulse 1 And (4) a pulse sequence, which triggers the counting end of the data acquisition card for multiple times, repeats the steps S1-S4 for multiple times to read the photon counting numerical value for multiple times, and records the numerical value read each time through a Labview control module.
S5.3, it should be noted that the frequency and the pulse width of the pulse signals acting on the exciting light and the logic gate of the data acquisition card are determined by the frequency, the pulse width and the duty ratio of the sequencer, in the scheme, the frequency of the exciting light pulse is selected to be 10KHZ, the pulse width is 50us under the condition that the duty ratio is 50%, and the corresponding trigger pulse frequency of the data acquisition card is 20KHZ.
S6: and (3) drawing a time-varying image of the number of fluorescence photons through an image production module:
and (5) displaying the value of each photon counting obtained in the step (S5) in a Labview display control form, and connecting a oscillogram for displaying the change relation of the photon counting along with time. As shown in fig. 4.
Therefore, the synchronous detection control system of the low-intensity optical signal based on the Labview is completed.
The above embodiments are only exemplary embodiments of the present invention, and are not intended to limit the present invention, and the scope of the present invention is defined by the claims. Various modifications and equivalents may be made by those skilled in the art within the spirit and scope of the present invention, and such modifications and equivalents should also be considered as falling within the scope of the present invention.
Claims (5)
1. The synchronous detection control system of the low-intensity light signal based on labview is characterized in that: the system comprises a low-intensity optical signal generating module, a data acquisition module, a sequence generating module, an image generating module and a Labview control module, wherein the data acquisition module, the sequence generating module and the image generating module are all in communication connection with the Labview control module, the low-intensity optical signal generating module is connected with the data acquisition module, and the sequence generating module acts on the low-intensity optical signal generating module and the data acquisition module.
2. The Labview-based synchronous detection control system for the low-intensity light signals, according to claim 1, is characterized in that the Labview control module controls the sequence generation module to generate a pulse sequence, the pulse sequence generated by the sequence generation module acts on the low-intensity light signal generation module and the data acquisition module, the data acquisition module sends acquired data to the Labview control module, the Labview control module sends the data acquired by the data acquisition module to the image generation module, and the image generation module performs image drawing.
3. The labview-based synchronous detection control system for low-intensity light signals according to claim 1, wherein the low-intensity light signal generation module comprises a laser, a dichroic mirror, a filter and an objective lens, the data acquisition module comprises a single photon counter and a data acquisition card, and the sequence generation module comprises a sequence generator.
4. The control method for the labview-based synchronous detection control system for low-intensity light signals according to any one of claims 1 to 3, characterized by comprising the steps of:
step 1, a Labview control module controls a sequence generation module to generate a pulse sequence with a pulse width t to act on a low-intensity light signal generation module, and the low-intensity light signal generation module emits exciting light with duration time equal to the pulse width t;
step 2, the sequence generation module synchronously sends out a second pulse width t at the rising edge of the pulse sequence with the pulse width t 1 The pulse sequence acts on the data acquisition module, and the data acquisition module reads out the number of instantaneous photons as X 1 ；
Step 3, the sequence generation module synchronously sends out a second pulse width t at the falling edge of the pulse sequence with the pulse width t 1 The pulse sequence acts on the data acquisition module, and the data acquisition module reads out the number of instantaneous photons as X 2 ；
Step 4, the instantaneous photon number X obtained in the steps 2 and 3 is used 1 、X 2 Sending the data to a Labview control module, and controlling the image generation module to X by the Labview control module 1 、X 2 Performing subtraction to obtain pulse photon counting with single pulse width t;
step 5, repeating the steps 1-4 to obtain photon counting signals for N times;
and 6, drawing a time-photon counting curve through an image generation module according to the N photon technology signals obtained in the step 5.
5. The control method of the labview-based synchronous detection control system for low-intensity light signals according to claim 4, wherein the excitation light is emitted from the low-intensity light signal generation module in the step 1 by: the pulse sequence with the pulse width being t and generated by the sequence generation module acts on the low-intensity optical signal generation module, so that the low-intensity optical signal generation module emits exciting light with the duration being equal to the pulse width t, the exciting light is focused through the dichroic mirror and the objective lens to excite a sample, the number of fluorescence photons generated after the sample is excited is collimated and collected through the objective lens again, and the fluorescence collected by the objective lens passes through the dichroic mirror and then is filtered through the long-pass, band-pass and short-pass filter plates in sequence.
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