CN115445033B - 药物递送系统及相关方法 - Google Patents

药物递送系统及相关方法 Download PDF

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Publication number
CN115445033B
CN115445033B CN202210749962.1A CN202210749962A CN115445033B CN 115445033 B CN115445033 B CN 115445033B CN 202210749962 A CN202210749962 A CN 202210749962A CN 115445033 B CN115445033 B CN 115445033B
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CN
China
Prior art keywords
aerosol delivery
delivery unit
canister
sealing member
discharge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202210749962.1A
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English (en)
Chinese (zh)
Other versions
CN115445033A (zh
Inventor
J·舍伍德
D·迪顿
D·海默尔
B·福斯特
M·菲瑞特尔
S·K·德威维迪
M·L·金
F·哈姆林
小R·V·希伊
G·利比
V·奈吉
K·伍达德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pearl Therapeutics Inc
Original Assignee
Pearl Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=66101724&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN115445033(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pearl Therapeutics Inc filed Critical Pearl Therapeutics Inc
Priority to CN202210749962.1A priority Critical patent/CN115445033B/zh
Publication of CN115445033A publication Critical patent/CN115445033A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/06—Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
    • A61M11/08—Pocket atomisers of the injector type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10—Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042—Components or details
    • B05B11/1052—Actuation means
    • B05B11/1053—Actuation means combined with means, other than pressure, for automatically opening a valve during actuation; combined with means for automatically removing closures or covers from the discharge nozzle during actuation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/38—Details of the container body
    • B65D83/384—Details of the container body the container body being an aerosol container located in an outer shell or in an external container
    • B65D83/386—Details of the container body the container body being an aerosol container located in an outer shell or in an external container actuation occurring by moving the aerosol container relative to the outer shell or external container
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/062—Desiccants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN202210749962.1A 2017-10-09 2018-10-05 药物递送系统及相关方法 Active CN115445033B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210749962.1A CN115445033B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762569901P 2017-10-09 2017-10-09
US62/569,901 2017-10-09
US201862639911P 2018-03-07 2018-03-07
US62/639,911 2018-03-07
CN201880079337.2A CN111432865B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法
CN202210749962.1A CN115445033B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法
PCT/US2018/054721 WO2019074799A1 (en) 2017-10-09 2018-10-05 DRUG DELIVERY SYSTEMS AND ASSOCIATED METHODS

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201880079337.2A Division CN111432865B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法

Publications (2)

Publication Number Publication Date
CN115445033A CN115445033A (zh) 2022-12-09
CN115445033B true CN115445033B (zh) 2024-08-27

Family

ID=66101724

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202210749962.1A Active CN115445033B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法
CN201880079337.2A Active CN111432865B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201880079337.2A Active CN111432865B (zh) 2017-10-09 2018-10-05 药物递送系统及相关方法

Country Status (12)

Country Link
US (3) US11833292B2 (enExample)
EP (2) EP3694590B1 (enExample)
JP (2) JP7076538B2 (enExample)
KR (2) KR102683072B1 (enExample)
CN (2) CN115445033B (enExample)
AU (2) AU2018347970B2 (enExample)
CA (1) CA3078209A1 (enExample)
ES (2) ES2921305T3 (enExample)
IL (2) IL273713B2 (enExample)
MY (1) MY201084A (enExample)
SG (1) SG11202003062QA (enExample)
WO (1) WO2019074799A1 (enExample)

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IL273713B2 (en) * 2017-10-09 2023-10-01 Pearl Therapeutics Inc Drug delivery systems and related methods
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IL309888A (en) 2021-07-09 2024-03-01 Astrazeneca Pharmaceuticals Lp Aerosol drug delivery compounds, methods and systems
FR3126002B1 (fr) * 2021-08-03 2023-08-04 G H Mumm Et Cie Soc Vinicole De Champagne Successeur Procédé et dispositif pour stocker et contrôler l’ouverture et la fermeture d’une cartouche contenant une boisson
CN115364317B (zh) * 2022-08-25 2023-07-14 翟凌 雾化结构、双头雾化器和雾化器
WO2025129008A1 (en) * 2023-12-13 2025-06-19 Csp Technologies, Inc. Aerosol delivery device, components thereof, and methods for making the same
WO2025130690A1 (zh) * 2023-12-19 2025-06-26 长风药业股份有限公司 剂量计数器及吸入器

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CN105193773A (zh) * 2009-05-29 2015-12-30 珍珠治疗公司 活性剂的呼吸递送

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Also Published As

Publication number Publication date
KR102683072B1 (ko) 2024-07-08
CN115445033A (zh) 2022-12-09
CN111432865A (zh) 2020-07-17
JP2022122887A (ja) 2022-08-23
AU2024205820A1 (en) 2024-09-05
EP4091652B1 (en) 2023-11-29
AU2018347970B2 (en) 2024-05-30
US20200353185A1 (en) 2020-11-12
KR102428545B1 (ko) 2022-08-04
IL273713B1 (en) 2023-06-01
WO2019074799A1 (en) 2019-04-18
US11833292B2 (en) 2023-12-05
IL302619A (en) 2023-07-01
IL273713A (en) 2020-05-31
EP4091652A1 (en) 2022-11-23
EP3694590B1 (en) 2022-05-04
EP3694590A1 (en) 2020-08-19
IL302619B1 (en) 2024-02-01
AU2018347970A1 (en) 2020-04-23
CA3078209A1 (en) 2019-04-18
JP2020536622A (ja) 2020-12-17
JP7076538B2 (ja) 2022-05-27
ES2921305T3 (es) 2022-08-23
US20220016366A1 (en) 2022-01-20
KR20200070284A (ko) 2020-06-17
KR20220110868A (ko) 2022-08-09
CN111432865B (zh) 2022-07-19
IL273713B2 (en) 2023-10-01
IL302619B2 (en) 2024-06-01
US20240050670A1 (en) 2024-02-15
EP3694590A4 (en) 2021-08-18
BR112020006696A2 (pt) 2020-10-06
ES2970740T3 (es) 2024-05-30
US11331442B2 (en) 2022-05-17
JP7479420B2 (ja) 2024-05-08
MY201084A (en) 2024-02-03
SG11202003062QA (en) 2020-04-29

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