CN115444371A - Smell test device - Google Patents
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- CN115444371A CN115444371A CN202211196189.7A CN202211196189A CN115444371A CN 115444371 A CN115444371 A CN 115444371A CN 202211196189 A CN202211196189 A CN 202211196189A CN 115444371 A CN115444371 A CN 115444371A
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- 238000012360 testing method Methods 0.000 title claims abstract description 61
- WRMNZCZEMHIOCP-UHFFFAOYSA-N 2-phenylethanol Chemical compound OCCC1=CC=CC=C1 WRMNZCZEMHIOCP-UHFFFAOYSA-N 0.000 claims abstract description 80
- 230000035943 smell Effects 0.000 claims abstract description 44
- 239000003292 glue Substances 0.000 claims abstract description 41
- 239000003085 diluting agent Substances 0.000 claims abstract description 35
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 33
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 30
- 230000008786 sensory perception of smell Effects 0.000 claims description 24
- ZSBWUNDRDHVNJL-UHFFFAOYSA-N 2-Methyl-2-cyclopenten-1-one Chemical compound CC1=CCCC1=O ZSBWUNDRDHVNJL-UHFFFAOYSA-N 0.000 claims description 22
- XYHKNCXZYYTLRG-UHFFFAOYSA-N 1h-imidazole-2-carbaldehyde Chemical compound O=CC1=NC=CN1 XYHKNCXZYYTLRG-UHFFFAOYSA-N 0.000 claims description 15
- GWYFCOCPABKNJV-UHFFFAOYSA-M 3-Methylbutanoic acid Natural products CC(C)CC([O-])=O GWYFCOCPABKNJV-UHFFFAOYSA-M 0.000 claims description 15
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims description 15
- 239000005770 Eugenol Substances 0.000 claims description 15
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims description 15
- 229940072049 amyl acetate Drugs 0.000 claims description 15
- PGMYKACGEOXYJE-UHFFFAOYSA-N anhydrous amyl acetate Natural products CCCCCOC(C)=O PGMYKACGEOXYJE-UHFFFAOYSA-N 0.000 claims description 15
- GWYFCOCPABKNJV-UHFFFAOYSA-N beta-methyl-butyric acid Natural products CC(C)CC(O)=O GWYFCOCPABKNJV-UHFFFAOYSA-N 0.000 claims description 15
- 229960002217 eugenol Drugs 0.000 claims description 15
- MNWFXJYAOYHMED-UHFFFAOYSA-M heptanoate Chemical compound CCCCCCC([O-])=O MNWFXJYAOYHMED-UHFFFAOYSA-M 0.000 claims description 15
- 235000013555 soy sauce Nutrition 0.000 claims description 13
- JDLKFOPOAOFWQN-VIFPVBQESA-N Allicin Natural products C=CCS[S@](=O)CC=C JDLKFOPOAOFWQN-VIFPVBQESA-N 0.000 claims description 11
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 claims description 11
- 235000010081 allicin Nutrition 0.000 claims description 11
- GTELLNMUWNJXMQ-UHFFFAOYSA-N 2-ethyl-2-(hydroxymethyl)propane-1,3-diol;prop-2-enoic acid Chemical group OC(=O)C=C.OC(=O)C=C.OC(=O)C=C.CCC(CO)(CO)CO GTELLNMUWNJXMQ-UHFFFAOYSA-N 0.000 claims description 8
- FRPZMMHWLSIFAZ-UHFFFAOYSA-N 10-undecenoic acid Chemical compound OC(=O)CCCCCCCCC=C FRPZMMHWLSIFAZ-UHFFFAOYSA-N 0.000 claims description 5
- KHAVLLBUVKBTBG-UHFFFAOYSA-N caproleic acid Natural products OC(=O)CCCCCCCC=C KHAVLLBUVKBTBG-UHFFFAOYSA-N 0.000 claims description 5
- YMCOIFVFCYKISC-UHFFFAOYSA-N ethoxy-[2-(2,4,6-trimethylbenzoyl)phenyl]phosphinic acid Chemical group CCOP(O)(=O)c1ccccc1C(=O)c1c(C)cc(C)cc1C YMCOIFVFCYKISC-UHFFFAOYSA-N 0.000 claims description 5
- 229960002703 undecylenic acid Drugs 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 2
- 238000013095 identification testing Methods 0.000 abstract description 8
- 239000000796 flavoring agent Substances 0.000 description 16
- 235000019634 flavors Nutrition 0.000 description 16
- ZDPHROOEEOARMN-UHFFFAOYSA-N undecanoic acid Chemical compound CCCCCCCCCCC(O)=O ZDPHROOEEOARMN-UHFFFAOYSA-N 0.000 description 14
- 235000019645 odor Nutrition 0.000 description 12
- 239000000499 gel Substances 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 5
- 208000012898 Olfaction disease Diseases 0.000 description 4
- 206010034018 Parosmia Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- -1 2,4, 6-trimethylbenzoyl phenyl ethyl Chemical group 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 240000002234 Allium sativum Species 0.000 description 2
- 244000144730 Amygdalus persica Species 0.000 description 2
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- 240000008790 Musa x paradisiaca Species 0.000 description 2
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- 235000006040 Prunus persica var persica Nutrition 0.000 description 2
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000002781 deodorant agent Substances 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000006870 function Effects 0.000 description 2
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- 210000001331 nose Anatomy 0.000 description 2
- 230000003997 social interaction Effects 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- FZUUHEZQCQGYNX-UHFFFAOYSA-N 2-methyl-tridecanoic acid Chemical compound CCCCCCCCCCCC(C)C(O)=O FZUUHEZQCQGYNX-UHFFFAOYSA-N 0.000 description 1
- 208000017194 Affective disease Diseases 0.000 description 1
- 208000024827 Alzheimer disease Diseases 0.000 description 1
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- 208000018737 Parkinson disease Diseases 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4005—Detecting, measuring or recording for evaluating the nervous system for evaluating the sensory system
- A61B5/4011—Evaluating olfaction, i.e. sense of smell
Abstract
The invention discloses a smell test device, which belongs to the technical field of smell test and comprises a plurality of first bases and a plurality of second bases, wherein containers are respectively arranged on each first base and each second base, the containers on the first bases are used for placing phenylethanol smell glues with different concentrations, and the containers on the second bases are used for placing identification smell glues with different smells; the phenethyl alcohol olfactory gum comprises the following components in percentage by mass: 0.25 to 0.5 percent of photoinitiator, 20 to 99.75 percent of diluent and 0 to 80 percent of phenethyl alcohol. The smell test device comprises a first base, a second base, a third base, a fourth base and a fourth base, wherein the first base is provided with phenylethanol smelling glues with different concentrations, the phenylethanol smelling glues are used for smell threshold test and testing taste thresholds of testees, and the second base is provided with identification smelling glues with different smells and used for smell identification test.
Description
Technical Field
The invention relates to the technical field of smell test, in particular to a smell test device.
Background
The sense of smell is one of the special senses of human beings, and plays an important role in social interaction and daily life of people. The olfactory disorder can affect the life quality, social interaction, nutrient intake of people and even threaten the life safety. In addition, olfactory disorder is also related to neurodegenerative disease, affective disorder and mental disease, and the like, and is an early warning signal of Parkinson's disease and Alzheimer's disease, and senile olfactory disorder and high mortality are related. Therefore, the olfaction test has great clinical significance for the prevention and treatment work of diseases.
At present, the sniff stick test of Sniffin' Sticks in Germany can comprehensively evaluate the threshold value, the recognition and the discrimination function of the smell, and is widely used at home and abroad. The odor threshold test was performed using 48 pen-shaped test sticks, each 3 test sticks were divided into 1 group of 16 groups, each group contained 2 blank controls, 1 test stick was an n-butanol solution, the highest score was 16, and the lowest score was 0. The odor recognition test comprises 16 pen-shaped test sticks, and after each sniffing stick is sniffed by a subject, one correct answer is selected from 4 answers provided by the subject, and all the selected correct answers are 16 points. The smell distinguishing test consists of 48 pen-shaped test bars, each 3 test bars are 1 group and 16 groups, wherein 2 test bars contain the same smell solution, 1 test bar contains other smell agents, all groups can be distinguished into 16 groups, after the three tests are finished, the sum of scores of three tests, namely an smell threshold value (T), a smell distinguishing (D) and an odor identification (I) is a TDI total score, so that the smell function is evaluated, the price of the smell bar is high, about 3 ten thousand RMB/set, the time is consumed from the purchase abroad for half a year to one year, and the smell bar is only used by large domestic medical and research hospitals or research institutions with intention or strength. And the olfaction threshold value and the identification and discrimination ability of one patient need to be tested for 30-50 minutes, and the olfaction test is difficult to popularize in the clinical or olfaction screening work and other works by combining the reasons of high price, difficult purchase and long time consumption of the olfaction stick.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide the smell test device which can perform smell threshold value and smell identification tests, is convenient and fast, is easy to take and place and has low cost.
In order to achieve the purpose, the invention adopts the technical scheme that:
a smell test device comprises a plurality of first bases and a plurality of second bases, wherein containers are placed on each of the first bases and the second bases, phenylethanol smelling glue with different concentrations is placed on the containers on the first bases, and identification smelling glue with different smells is placed on the containers on the second bases;
the phenethyl alcohol olfactory gum comprises the following components in percentage by mass: 0.25-0.5% of photoinitiator, 20-99.75% of diluent and 0-80% of phenethyl alcohol.
The containers are provided with bottle caps, and the bottle caps are used for closing the containers when the containers are not used.
The inventor of the invention finds in a large number of researches that phenylethanol olfactory glues with different concentrations are placed on the first base and used for olfactory threshold test and gustatory threshold test of a testee, and identification olfactory glues with different smells are placed on the second base and used for olfactory identification test, so that the olfactory testing device can be used for olfactory threshold and olfactory identification test, and is convenient and fast, easy to take and place and low in cost.
In addition, it should be noted that, the distance between the first base and the second base can be adjusted by those skilled in the art according to actual needs.
Further, as for the container, it is a conventional container.
As a preferred embodiment of the present invention, the photoinitiator is ethyl 2,4, 6-trimethylbenzoylphenylphosphonate; the diluent is ethoxylated trimethylolpropane triacrylate. The inventor of the invention finds that when 2,4, 6-trimethylbenzoyl phenyl ethyl phosphonate is selected as a photoinitiator and ethoxylated trimethylolpropane triacrylate is selected as a diluent, the olfactory agent can be stably stored in the olfactory adhesive for a long time, is not easy to volatilize, is safe and harmless, and has wide application prospect.
In a preferred embodiment of the present invention, the number of the first bases is 5 to 17.
In a preferred embodiment of the present invention, the number of the first bases is 5, and the containers on the first bases are respectively filled with the phenylethanol smelling glue with mass concentrations of 0%, 20%, 40%, 60% and 80%.
In a preferred embodiment of the present invention, the number of the first bases is 10, and the containers on the first bases are respectively filled with the phenylethanol smelling glue with a mass concentration of 0%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%. When 10 first bases are arranged according to the mass concentration, the smell threshold testing effect is best.
In a preferred embodiment of the present invention, the number of the first bases is 17, and the containers on the first bases are respectively filled with the phenylethanol smelling glue with a mass concentration of 0%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75% and 80%.
As a preferred embodiment of the invention, the olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of olfactin.
As a preferred embodiment of the present invention, the photoinitiator is ethyl 2,4, 6-trimethylbenzoylphenylphosphonate; the diluent is ethoxylated trimethylolpropane triacrylate. When 2,4, 6-trimethylbenzoyl phenyl ethyl phosphonate is selected as a photoinitiator and ethoxylated trimethylolpropane triacrylate is selected as a diluent, the odor agent can be stably stored in the odor glue for a long time, is not easy to volatilize, is safe and harmless, and has wide application prospect.
In a preferred embodiment of the present invention, the sniffine is one of amyl acetate, eugenol, isovaleric acid, undecaprionic acid, soy sauce, methylcyclopentenone, allicin and acetic acid.
As a preferred embodiment of the invention, the number of the second bases is 8, and the containers on the second bases respectively contain olfactory gum for storing amyl acetate, eugenol, isovaleric acid, undecylenic acid, soy sauce, methyl cyclopentenone, allicin and acetic acid. Different types of olfactin are placed on the second base, wherein amyl acetate of the olfactin represents banana flavor, eugenol represents clove flavor, isovaleric acid represents smelly sock flavor, undecanoic acid represents cooked peach flavor, soy sauce represents soy sauce flavor, methylcyclopentenone represents sweet burnt paste flavor, allicin represents garlic flavor, and acetic acid represents edible vinegar flavor. Can effectively carry out olfaction identification test.
The invention has the beneficial effects that: (1) According to the olfaction testing device, the phenylethanol olfactory glues with different concentrations are placed on the first base and used for olfaction threshold testing and taste threshold testing of a subject, and the identification olfactory glues with different smells are placed on the second base and used for olfaction identification testing, so that the olfaction testing device can be used for olfaction threshold and olfaction identification testing, and is convenient and fast to carry, easy to take and place and low in cost; (2) The invention takes 2,4, 6-trimethylbenzoyl phenyl ethyl phosphonate as a photoinitiator and ethoxylated trimethylolpropane triacrylate as a diluent, so that the deodorant can be stably stored in the deodorant for a long time, is not easy to volatilize, is safe and harmless, and has wide application prospect; (3) The olfactory testing device disclosed by the invention is simple in preparation process, short in time consumption and capable of effectively replacing a Sniffin' Sticks olfactory stick.
Drawings
Fig. 1 is a schematic structural diagram of the olfaction testing device of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are a part of the embodiments of the present invention, but not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The reagents or instruments used in the present invention are not indicated by manufacturers, and are all conventional products commercially available.
Example 1
Referring to fig. 1, the present embodiment provides an olfactory testing device, which includes 10 first bases 1 and 8 second bases 2, wherein each of the first bases and the second bases is disposed with a container (the container is not shown in the figure), the containers on the first bases are disposed with phenylethanol olfactory glue of different concentrations, and the containers on the second bases are disposed with identification olfactory glue of different odors.
Taking phenylethanol olfactory gel with mass concentration of 20% as an example, the phenylethanol olfactory gel comprises the following components in percentage by mass: 0.25% of photoinitiator, 79.75% of diluent and 20% of phenethyl alcohol; when preparing the phenethyl alcohol smelling glue with different mass concentrations, the amount of the diluent is only required to be changed.
The container on the first base is sequentially (from 10 to 19) provided with phenethyl alcohol smelling glue with mass concentration of 0%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70% and 80%.
As for the container, it is a conventional container, and its volume is 1.5mL.
The container on the second base is sequentially provided with amyl acetate olfactory gum with the mass concentration of 50%, eugenol olfactory gum with the mass concentration of 50%, isovaleric acid olfactory gum with the mass concentration of 50%, undecylpropionic acid olfactory gum with the mass concentration of 50%, soy sauce olfactory gum with the mass concentration of 50%, methyl cyclopentenone olfactory gum with the mass concentration of 50%, allicin olfactory gum with the mass concentration of 50% and acetic acid olfactory gum with the mass concentration of 50%.
The 50% amyl acetate olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of amyl acetate.
The 50% eugenol olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of eugenol.
The 50% isovaleric acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of isovaleric acid.
The 50% undecanoic acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of undecanoic acid.
The 50% soy sauce smelling glue comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of soy sauce.
The 50% methyl cyclopentenone olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of methyl cyclopentenone.
The 50% allicin olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of allicin.
The 50% acetic acid smelly glue comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of acetic acid.
In this example, the photoinitiator was ethyl 2,4, 6-trimethylbenzoylphenylphosphonate; the diluent is ethoxylated trimethylolpropane triacrylate.
Example 2
Referring to fig. 1, the present embodiment provides an olfactory testing device, which includes 17 first bases and 8 second bases 2, wherein each of the first bases and the second bases is disposed with a container, the containers on the first bases are disposed with phenylethanol smelling glue of different concentrations, and the containers on the second bases are disposed with identification smelling glue of different odors.
Taking phenylethanol olfactory gel with mass concentration of 20% as an example, the phenylethanol olfactory gel comprises the following components in percentage by mass: 0.25% of photoinitiator, 79.75% of diluent and 20% of phenethyl alcohol; when preparing the phenethyl alcohol olfactory glue with different mass concentrations, only the amount of the diluent is required to be changed.
The container on the first base is sequentially provided with phenylethanol smelling glue with mass concentration of 0%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75% and 80%.
As for the container, it is a conventional container, and its volume is 1.5mL.
And a container on the second base is sequentially and respectively provided with amyl acetate olfactory gum with the mass concentration of 50%, eugenol olfactory gum with the mass concentration of 50%, isovaleric acid olfactory gum with the mass concentration of 50%, undecylenic acid olfactory gum with the mass concentration of 50%, soy sauce olfactory gum with the mass concentration of 50%, methyl cyclopentenone olfactory gum with the mass concentration of 50%, allicin olfactory gum with the mass concentration of 50% and acetic acid olfactory gum with the mass concentration of 50%.
The 50% amyl acetate olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of amyl acetate.
The 50% eugenol olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of eugenol.
The 50% isovaleric acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of isovaleric acid.
The 50% undecanoic acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of undecanoic acid.
Example 3
Referring to fig. 1, the present embodiment provides an olfactory testing device, which includes 5 first bases and 8 second bases 2, wherein each of the first bases and the second bases is disposed with a container, the containers on the first bases are disposed with phenylethanol smelling glue of different concentrations, and the containers on the second bases are disposed with identification smelling glue of different odors.
Taking phenylethanol olfactory gel with mass concentration of 20% as an example, the phenylethanol olfactory gel comprises the following components in percentage by mass: 0.25% of photoinitiator, 79.75% of diluent and 20% of phenethyl alcohol; when preparing the phenethyl alcohol smelling glue with different mass concentrations, the amount of the diluent is only required to be changed.
The container on the first base is sequentially provided with 0%, 20%, 40%, 60%, 65% and 80% of phenethyl alcohol smelling glue in sequence.
As for the container, it is a conventional container, and its volume is 1.5mL.
And a container on the second base is sequentially and respectively provided with amyl acetate olfactory gum with the mass concentration of 50%, eugenol olfactory gum with the mass concentration of 50%, isovaleric acid olfactory gum with the mass concentration of 50%, undecylenic acid olfactory gum with the mass concentration of 50%, soy sauce olfactory gum with the mass concentration of 50%, methyl cyclopentenone olfactory gum with the mass concentration of 50%, allicin olfactory gum with the mass concentration of 50% and acetic acid olfactory gum with the mass concentration of 50%.
The 50% amyl acetate olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of amyl acetate.
The 50% eugenol olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of eugenol.
The 50% isovaleric acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of isovaleric acid.
The 50% undecanoic acid olfactory gum comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of undecanoic acid.
Test example 1
1. The olfactory test device of embodiment 1 is used for olfactory test, and the test method specifically comprises the following steps:
1. the personal information of the subject is registered.
2. Start olfactory threshold test: the testing is carried out in sequence from low concentration to high concentration of the phenethyl alcohol, a tester opens a storage bottle cap containing 0% phenethyl alcohol olfactory gel (namely a blank group), the odorant is fully exposed, the storage bottle cap is placed in front of the nose of a testee for a period of several seconds, then the storage bottle is removed, the tester is asked whether to smell the odor, if not, the olfactory agent with the next concentration gradient is tested, the test interval between two adjacent olfactory gels is 30 seconds, the rest is repeated until the testee can smell the odor, the concentration of the olfactory agent which can be smelled is recorded, namely the olfactory threshold value of the patient, and if the concentration is the highest concentration, namely 80% phenethyl alcohol testee cannot smell the odor, the testee is judged to lose the odor.
3. Olfaction identification test: setting an alternative answer card corresponding to the smell of the olfactory gum according to the smell representative smell of the olfactory gum, wherein the olfactory gum is amyl acetate to represent banana flavor, eugenol to represent clove flavor, isovaleric acid to represent smelly sock flavor, undecylenic acid to represent cooked peach flavor, soy sauce to represent soy sauce flavor, methyl cyclopentenone to represent sweet burnt paste flavor, allicin to represent garlic flavor, and acetic acid to represent vinegar flavor; the method comprises the steps that a detector opens any one of the sniffing glue storage bottle caps, the odorant is fully exposed, the sniffing glue storage bottle caps are placed in front of the noses of a tested person for a few seconds, the sniffing glue is removed, an alternative answer card is provided for the tested person to select the smelling and the sniffing smell representing the smell, the same tested person can smell the sniffing glue once, and if the tested person cannot identify the smelling smell, the same sniffing glue cannot be smelled again.
2. 20 examined persons with normal subjective smell and 12 subjective dysosmia (3 chronic nasosinusitis patients, 6 allergic rhinitis patients, 1 virus infected dysosmia, 1 traumatic dysosmia and 1 unknown cause dysosmia) are selected, a German Sniffin' Sticks sniff stick and the novel olfactory patch are sequentially adopted to carry out olfactory test, and olfactory examination results are divided into three grades: normal, decline, loss (indicated by 1, 2, 3). And (3) carrying out Kappa consistency test on the test result, and prompting the test result: the two test diagnoses were highly consistent, kappa =0.847 and p-straw 0.01.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (10)
1. The smell test device is characterized by comprising a plurality of first bases and a plurality of second bases, wherein containers are placed on each of the first bases and the second bases, the containers on the first bases are used for holding phenethyl alcohol smell glues with different concentrations, and the containers on the second bases are used for holding identification smell glues with different smells;
the phenethyl alcohol olfactory gum comprises the following components in percentage by mass: 0.25 to 0.5 percent of photoinitiator, 20 to 99.75 percent of diluent and 0 to 80 percent of phenethyl alcohol.
2. The olfaction test device of claim 1, wherein the photoinitiator is ethyl 2,4, 6-trimethylbenzoylphenylphosphonate;
the diluent is ethoxylated trimethylolpropane triacrylate.
3. The olfaction test device according to claim 1, wherein the number of the first bases is 5 to 17.
4. The olfaction test device of claim 1, wherein the number of the first bases is 5, and the containers on the first bases are filled with 0%, 20%, 40%, 60% and 80% of phenylethanol olfactory glue by mass concentration.
5. The olfaction test device according to claim 1, wherein the number of the first bases is 10, and the containers on the first bases are respectively filled with phenylethanol smelling glue with mass concentration of 0%, 5%, 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%.
6. The olfaction test device according to claim 1, wherein the number of the first bases is 17, and the containers on the first bases are respectively filled with phenylethanol smelling glue with a mass concentration of 0%, 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%.
7. The olfaction test device according to claim 1, wherein the identification olfactory glue comprises the following components in percentage by mass: 0.25% of photoinitiator, 49.75% of diluent and 50% of olfactin.
8. The olfaction test device of claim 7, wherein the photoinitiator is ethyl 2,4, 6-trimethylbenzoylphenylphosphonate;
the diluent is ethoxylated trimethylolpropane triacrylate.
9. The olfaction test device according to claim 7, wherein the olfactin is one of amyl acetate, eugenol, isovaleric acid, undecapropionic acid, soy sauce, methylcyclopentenone, allicin, and acetic acid.
10. The olfaction test device according to claim 8, wherein the number of the second bases is 8, and the containers on the second bases are respectively olfactory glues for storing amyl acetate, eugenol, isovaleric acid, undecylenic acid, soy sauce, methylcyclopentenone, allicin and acetic acid.
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