CN115408460A - Information integration system for vaccine production process - Google Patents
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Abstract
The invention discloses an information integration system in a vaccine production process, which comprises an MES system and a plurality of information systems, wherein the information systems are respectively connected with the MES system through a data processing server, the data processing server comprises an information data conversion server which is used for analyzing data received by the MES system and converting the data format into a specified format through java codes, the data format comprises an XML or json format, and the data between the MES system and the information systems are communicated and exchanged in the specified format. The information integration system for the vaccine production process can reduce repeated development of information interfaces in the vaccine production process, improve information integration efficiency, and uniformly manage data in the vaccine production process, so that data access and updating efficiency is improved, adverse consequences caused by data repetition and data redundancy are eliminated, and safety, authenticity and integrity of the data in the vaccine production process are guaranteed.
Description
Technical Field
The invention relates to the technical field of vaccine production management, in particular to an information integration system in a vaccine production process.
Background
The safety and the effectiveness of the vaccine are directly related to the physical health of people, and relate to public safety and national safety. Meanwhile, in the notice of the revised manuscript in the annex of biological products in the PRC vaccine management Law and the pharmaceutical product quality management Specification (revised in 2010) (No. 58 in 2020), new requirements are put forward on the electronic record of the data in the vaccine production process and the authenticity, integrity and traceability of the data. With the promotion of national policies, vaccine production enterprises implement informatization systems in a dispute, and intelligent workshops and intelligent factories are established.
At present, interface development and butt joint among information systems are mostly adopted for vaccine factory information transmission, the workload of interface development is large due to the fact that the information systems and equipment are multiple in brands and equipment are multiple, the same data exists in a multi-service system in different forms due to the application of multiple systems, the situations of data repetition, multiple management and the like exist, data redundancy, loss and even damage exist, and the safety and the integrity of the data are difficult to guarantee.
Therefore, how to overcome the above-mentioned drawbacks and provide an integrated system of vaccine production process information is a problem that needs to be solved by those skilled in the art.
Disclosure of Invention
In view of the above, the information integration system of the vaccine production process is formed by taking the MES system as a core and topologically arranging the MES system to each system, so that repeated development of information interfaces in the vaccine production process is reduced, data is uniformly converted based on the MES system, and uniform management of the data in the vaccine production process is realized;
in order to achieve the purpose, the invention adopts the following technical scheme:
a vaccine production process information integration system comprising:
an MES system and a plurality of information systems, wherein the information systems are respectively connected with the MES system through a data processing server,
the data processing server comprises a data conversion server, the data conversion server is used for analyzing the data received by the MES system, and converting the data format into a specified format through java codes, and the data processing server comprises: in the XML or json format,
and data between the MES system and the information systems is communicated and exchanged in the specified format. In general, data in XML or json format has strong versatility, and each information system can recognize and process the data in the format received.
Further, the plurality of information systems include: ERP system, LIMS system, QMS system, WMS system and SCADA system.
Further, the interface modes supported by the data processing server include an API interface, OPC, web Service, socket, a database intermediate table, HTTP transmission and XML.
Furthermore, the data processing server comprises a data temporary storage server, which is used for temporarily storing data when the communication between the systems fails and automatically uploading the data after the communication is recovered;
further, the data processing server further includes a data retrieval server, configured to query information, where the query content specifically includes:
(1) Viewing an initiator, a receiver, time, content and an original data packet converted into a Json format of data received by the MES system;
(2) Viewing an interface document of the called interface;
(3) Checking the calling time, wherein the calling time is the time when the system processes the client and requests to record the current log;
(4) Checking a status code, wherein the status code comprises red and green, and when the status code is green, the data interaction is represented to be abnormal; when the status code is red, the bidding document data interaction is abnormal and needs to be checked.
Further, the formats include data specifications, classification codes, exchange formats, terms, and file formats.
Further, the data communication and information exchange process between the MES system and the plurality of information systems includes:
1) After the ERP system creates a production order and a material issuing order, the production order and the material issuing order are sent to the MES system, the MES system executes material receiving operation through the WMS system and receives material consumption information returned by the WMS system;
2) In the production process, the MES system reports the material consumption information to the ERP system;
3) After the production is finished, the MES system generates a semi-finished product/finished product request and sends the semi-finished product/finished product request to the LIMS system; and after the LIMS system finishes the inspection, sending the inspected result to the ERP system through the MES system, generating a warehousing entry to be sent to the WMS system, receiving warehousing information returned by the WMS system, and forwarding the warehousing information to the ERP system.
Further, the data communication and information exchange process further includes: in the production process, the MES system receives equipment operation data and production process data transmitted by the SCADA system in real time, and exchanges deviation, abnormal data and abnormal result data with the QMS system.
Further, the data types for data communication and information exchange between the MES system and the plurality of information systems include:
the data transmitted by the ERP system to the MES system is as follows: the system comprises a material issuing list, material main data, a production order, supplier information and BOM data;
the data transmitted by the QMS system to the MES system is as follows: deviation/anomalous results;
the data transmitted by the LIMS system to the MES system are as follows: checking results and a semi-finished product/finished product release order;
the data transmitted to the MES system by the SCADA system is as follows: equipment operation data and production process data;
the data transmitted to the MES by the WMS system is as follows: ex-warehouse information;
the data transmitted by the MES system to the ERP system is as follows: material consumption information, semi-finished product/finished product information, material receiving data, production working hour data and material returning information;
the data transmitted by the MES system to the LIMS system are as follows: please check the information;
the data transmitted by the MES system to the QMS system is: deviation/anomaly data;
the data transmitted to the SCADA system by the MES system is as follows: producing instructions;
the data transmitted by the MES system to the WMS system are as follows: and (7) warehousing.
Compared with the prior art, the vaccine production process information integration system disclosed by the invention has the advantages that the repeated development of vaccine production process information interfaces is reduced, the information integration efficiency is improved, the unified management of vaccine production process data is realized, the data access and update efficiency is improved, and adverse consequences caused by data repetition and data redundancy are eliminated, so that the safety, authenticity and integrity of the vaccine production process data are ensured, and the requirements of drug administration departments and regulation supervision are met.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic diagram of a vaccine production process information integration system provided by the invention;
fig. 2 is a schematic structural diagram of a data processing server according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the invention discloses an information integration system for a vaccine production process, which avoids repeated development of an information interface in the vaccine production process and realizes unified management of data in the vaccine production process.
In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, the present invention is described in detail with reference to the accompanying drawings and the detailed description thereof.
The information integration system for the vaccine production process provided by the embodiment of the invention comprises an MES system and a plurality of information systems, wherein the plurality of information systems comprise an ERP system, an LIMS system, a QMS system, a WMS system and an SCADA system, as shown in figure 1,
the system comprises an MES system, an ERP system, an LIMS system, a QMS system, a WMS system, an SCADA system and a quality management system, wherein the MES system is a manufacturing execution system, the ERP system is an enterprise resource planning system, the LIMS system is a laboratory information management system, the QMS is a quality management system, the WMS system is a warehouse management system and the SCADA system is a data acquisition and monitoring control system;
the multiple information systems are respectively connected with the MES system through the data processing server to realize data communication and information exchange, and further, the data processing server supports multiple interface modes, specifically: API interface, OPC, web Service, socket, intermediate table of database, HTTP transmission and XML;
wherein, in order to avoid the situation that the same data exists in the system in different forms to cause data repetition, multiple management and the like, thereby causing data redundancy, loss and even damage, the data processing server based on the MES system carries out uniform conversion on the received data,
specifically, the data processing server includes a data conversion server, as shown in fig. 2, the data conversion server is configured to parse the data received by the MES system, convert the data format into a specified format through java code,
and the data between the MES system and the plurality of information systems is communicated and exchanged in the form of the specified format.
The specified format is that data specification, classification coding, exchange format, terminology and file format are all unified, and in one embodiment, the specified format includes: the XML or json format, and generally, data in the XML or json format has strong versatility, and data in the format can be identified and processed when received by each information system.
In addition, the data processing server also comprises a data temporary storage server which has a data temporary storage function, when the communication between the systems fails, the data temporary storage can be started, and the data is automatically uploaded after the communication is recovered;
further, in order to facilitate unified management of data, the data processing server is further provided with a data retrieval server for querying various information, and the query content specifically includes:
(1) Viewing an initiator, a receiver, time, content and an original data packet converted into a Json format, wherein the initiator, the receiver, the time and the content of data received by the MES system;
(2) Viewing an interface document of the called interface;
(3) Checking the calling time, wherein the calling time is the time when the system processes the client and requests to record the log; the client refers to an entrance and an interface for information query, and is usually embodied on a desktop computer, a tablet computer and a mobile phone;
(4) Checking a status code, wherein the status code comprises red and green, and when the status code is green, the data interaction is represented to be abnormal; when the status code is red, the data interaction is abnormal and needs to be checked;
further, the vaccine production process information integration system taking the MES system as the core has the following data and information exchange processes in work:
1) After the ERP system creates a production order and a material issuing order, the production order and the material issuing order are sent to the MES system, the MES system executes material receiving operation and receives material consumption information returned by the WMS system;
2) In the production process, the MES system reports the material consumption information to the ERP;
3) After the production is finished, the MES system generates a semi-finished product and a finished product request and check list and sends the semi-finished product and the finished product request and check list to the LIMS; and after LIMS inspection is finished, sending the inspected inspection result to ERP through MES, generating a warehousing entry and sending to WMS, and forwarding the received ex-warehouse information returned by the WMS to ERP.
Specifically, the LIMS sends the checked inspection result to the ERP and the QMS through the MES, the QMS carries out warehousing operation on qualified semi-finished products and finished products, sends warehousing information to the ERP system and the WMS through the MES, receives production flow information of the MES, analyzes reasons of quality problems of unqualified finished products and semi-finished products, and feeds the reasons back to the ERP system through the MES.
In addition, in the production process, the MES system receives the equipment operation data and the production process data transmitted by the SCADA system in real time, and exchanges deviation, abnormal data and abnormal result data with the QMS system.
The types of data information specifically transmitted among the systems are as follows:
the data transmitted by the ERP system to the MES system is as follows: the system comprises a material issuing list, material main data, a production order, supplier information and BOM data;
the data transmitted by the QMS system to the MES system is as follows: deviation/anomalous results;
the data transmitted by the LIMS system to the MES system are as follows: checking results and a semi-finished product/finished product release order;
the data transmitted by the SCADA system to the MES system is as follows: equipment operation data and production process data;
the data transmitted by the WMS system to the MES system is as follows: information of delivery from a warehouse;
the data transmitted by the MES system to the ERP system are as follows: material consumption information, semi-finished product/finished product information, material receiving data, production working hour data and material returning information;
the data transmitted by the MES system to the LIMS system are: please check the information;
the data transmitted by the MES system to the QMS system is: deviation/anomaly data;
the data transmitted by the MES system to the SCADA system are as follows: a production instruction;
the data transmitted by the MES system to the WMS system is as follows: and (7) warehousing the bill.
Wherein, the information data volume integrated and stored by the MES is 1000-5000 ten thousand.
In one embodiment, the working process of the vaccine production process information integration system disclosed by the invention is as follows:
before production:
(1) Creating a generation instruction in the ERP, and transmitting the generation instruction to the MES from the EPR after the quality part and the production part check the production instruction; meanwhile, the ERP sends basic material information (part) to MES; the MES system completes part of ERP missing fields, and the information of each material needs to be manually completed;
(2) The workshop creates a material getting request form according to the checked production instruction, and sends the material needing information to the ERP through the MES;
(3) A material issuing list is created in the ERP, is transmitted to the WMS through the MES, is used for executing material receiving operation and reports the material consumption to the ERP;
in the production process:
(4) In the production process, the SCADA transmits the equipment operation data and the production process data to the MES in real time;
after production:
(5) After the production operation is finished, the MES generates a semi-finished product and a finished product test request sheet and sends the semi-finished product and the finished product test request sheet to the LIMS;
(6) After the inspection is finished, the LIMS sends the inspected inspection result to the ERP and the QMS through the MES;
(7) The QMS executes warehousing operation on qualified semi-finished products and finished products, sends warehousing information to an ERP system and a WMS system through an MES system, receives production flow information of the MES system, analyzes reasons of quality problems of unqualified finished products and semi-finished products, and feeds the unqualified finished products and semi-finished products back to the ERP system through the MES system;
meanwhile, the MES system and the QMS system exchange deviation, abnormal data and abnormal result data.
In the present specification, the embodiments are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed in the embodiment corresponds to the method disclosed in the embodiment, so that the description is simple, and the relevant points can be referred to the description of the method part.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (9)
1. A vaccine production process information integration system, comprising:
an MES system and a plurality of information systems, wherein the plurality of information systems are respectively connected with the MES system through a data processing server,
the data processing server comprises a data conversion server, the data conversion server is used for analyzing the data received by the MES system and converting the data format into a specified format through java codes, and the data processing server comprises: in the XML or json format,
and the data between the MES system and the plurality of information systems is communicated and exchanged in the form of the specified format.
2. The vaccine production process information integration system according to claim 1, wherein the plurality of information systems comprise: ERP system, LIMS system, QMS system, WMS system and SCADA system.
3. The vaccine production process information integration system according to claim 1, wherein the interface modes supported by the data processing server comprise API interface, OPC, web Service, socket, database intermediate table, HTTP transmission and XML.
4. The information integration system for vaccine production process according to claim 1, wherein the data processing server further comprises a data temporary storage server for temporarily storing data when communication between systems fails and automatically uploading the data after communication is recovered.
5. The information integration system for vaccine production process according to claim 1, wherein the data processing server further comprises a data retrieval server for information query, the query comprises:
(1) Viewing an initiator, a receiver, time, content and an original data packet converted into a Json format of data received by the MES system;
(2) Viewing an interface document of the called interface;
(3) Checking the calling time, wherein the calling time is the time when the system processes the client and requests to record the log;
(4) Checking a status code, wherein the status code comprises red and green, and when the status code is green, the data interaction is represented to be abnormal; when the status code is red, it indicates that there is an exception in data interaction and needs to be checked.
6. The vaccine production process information integration system of claim 1, wherein the specified format comprises data specification, classification code, exchange format, terminology, and file format.
7. The information integration system of vaccine production process according to claim 2, wherein the data communication and information exchange process between the MES system and the plurality of information systems comprises:
1) After the ERP system creates a production order and a material issuing order, the production order and the material issuing order are sent to the MES system, the MES system executes material receiving operation through the WMS system and receives material consumption information returned by the WMS system;
2) In the production process, the MES system reports the material consumption information to the ERP system;
3) After the production is finished, the MES system generates a semi-finished product/finished product request and check list and sends the semi-finished product/finished product request and check list to the LIMS system; and after the LIMS system finishes the inspection, sending the inspected result to the ERP system through the MES system, generating a warehousing entry to be sent to the WMS system, receiving warehousing information returned by the WMS system, and forwarding the warehousing information to the ERP system.
8. The information integration system for vaccine production process according to claim 7, wherein the data communication and information exchange process further comprises: in the production process, the MES system receives equipment operation data and production process data transmitted by the SCADA system in real time, and exchanges deviation, abnormal data and abnormal result data with the QMS system.
9. The information integration system of vaccine production process according to claim 2, wherein the data types of data communication and information exchange between the MES system and the plurality of information systems comprise:
the data transmitted by the ERP system to the MES system is as follows: the system comprises a material issuing list, material main data, a production order, supplier information and BOM data;
the data transmitted by the QMS system to the MES system is as follows: deviation/anomalous results;
the data transmitted by the LIMS system to the MES system are as follows: checking results and a semi-finished product/finished product release order;
the data transmitted to the MES system by the SCADA system is as follows: equipment operation data and production process data;
the data transmitted to the MES system by the WMS system is as follows: ex-warehouse information;
the data transmitted to the ERP system by the MES system is as follows: material consumption information, semi-finished product/finished product information, material receiving data, production working hour data and material returning information;
the data transmitted by the MES system to the LIMS system are as follows: please check the information;
the data transmitted by the MES system to the QMS system is as follows: deviation/anomaly data;
the data transmitted to the SCADA system by the MES system is as follows: a production instruction;
the data transmitted by the MES system to the WMS system are as follows: and (7) warehousing the bill.
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| CN117314025A (en) * | 2023-11-29 | 2023-12-29 | 广东新亚光电缆股份有限公司 | Cable production process information system based on Internet of things |
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| CN117314025B (en) * | 2023-11-29 | 2024-05-10 | 广东新亚光电缆股份有限公司 | Cable production process information system based on Internet of things |
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