CN115381976B

CN115381976B - Method and device for sterilizing and disinfecting precision instruments and consumable materials by using cold plasma

Info

Publication number: CN115381976B
Application number: CN202211064018.9A
Authority: CN
Inventors: 常华梅; 方志; 金珊珊; 刘诗筠; 赵亚军; 时贞平
Original assignee: Jiangsu Rongzheng Pharmaceutical Technology Co ltd
Current assignee: Nanjing Jinyou Health Management Co ltd
Priority date: 2022-08-31
Filing date: 2022-08-31
Publication date: 2023-11-24
Anticipated expiration: 2042-08-31
Also published as: CN115381976A

Abstract

Embodiments of the present disclosure provide a method and apparatus for sterilization and disinfection of precision instruments and consumables using cold plasma. The sterilization and disinfection device comprises: the sterilization treatment bin is used for carrying out sterilization treatment on objects to be treated based on cold plasmas, wherein the sterilization treatment bin comprises a plasma generation electrode used for releasing the cold plasmas; and the controller is in communication connection with the sterilization treatment bin; the controller is used for: acquiring the exposed surface area and volume of an object to be treated; determining sterilization and disinfection parameters according to the exposed surface area and the volume; wherein the sterilization and disinfection parameters at least comprise a time parameter for releasing the cold plasma and a rotation parameter of the object to be treated in the sterilization treatment bin; and controlling the sterilization treatment bin to perform sterilization treatment on the object to be treated according to the sterilization and disinfection parameters.

Description

Method and device for sterilizing and disinfecting precision instruments and consumable materials by using cold plasma

Technical Field

The specification relates to the technical field of sterilization devices, in particular to a sterilization method and a sterilization device for precise instruments and consumable materials by using cold plasma.

Background

Some instruments used in medical systems need to be kept sterile, which places high demands on sterilization techniques. In addition, with the increase of food safety detection requirements, related fields such as pharmacy and food also need to sterilize specific articles or products. At present, the plasma sterilization treatment is applied to a plurality of fields, and has the advantages of reliable sterilization effect, high sterilization speed and the like. The plasma is adopted to disinfect the whole object, so that the problems that some severely polluted areas of the object are not completely disinfected and the like can occur.

Therefore, it is necessary to provide a sterilization and disinfection method and device for precise instruments and consumables by using cold plasma, which can be used for precisely determining the areas of articles needing important sterilization and determining parameters of sterilization and disinfection treatment, thereby effectively improving the sterilization and disinfection effect of the sterilization and disinfection treatment.

Disclosure of Invention

One or more embodiments of the present specification provide a sterilization and disinfection apparatus for precision instruments and consumables using cold plasma, a sterilization treatment bin for performing sterilization treatment on an object to be treated based on cold plasma, wherein the sterilization treatment bin includes a plasma generation electrode for releasing the cold plasma; and the controller is in communication connection with the sterilization treatment bin and is used for: acquiring the exposed surface area and volume of the object to be treated; determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of the sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin; and controlling the sterilization treatment bin to perform sterilization treatment on the object to be treated according to the sterilization and disinfection parameters.

One or more embodiments of the present specification provide a sterilization and disinfection method of cold plasma for precision instruments and consumables, the sterilization and disinfection method being applied to the sterilization and disinfection apparatus provided in the present specification, the method comprising: acquiring the exposed surface area and volume of an object to be treated; determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of a sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin; and controlling the sterilization treatment bin to perform sterilization treatment on the object to be treated according to the sterilization and disinfection parameters.

One or more embodiments of the present specification provide a cold plasma sterilization system for precision instruments, consumables; the sterilization and disinfection system comprises: the detection module is used for acquiring the exposed surface area and volume of the object to be treated; a calculation module for determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of a sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin; and the execution module is used for controlling the sterilization treatment bin execution equipment to perform sterilization treatment on the object to be treated according to the sterilization and disinfection parameters.

One or more embodiments of the present disclosure provide a computer-readable storage medium storing computer instructions that, when read by a computer in the storage medium, the computer performs a method of cold plasma sterilization for precision instruments, consumables.

Drawings

The present specification will be further elucidated by way of example embodiments, which will be described in detail by means of the accompanying drawings. The embodiments are not limiting, in which like numerals represent like structures, wherein:

FIG. 1 is a schematic illustration of an application scenario of a cold plasma sterilization system for precision instruments, consumables according to some embodiments of the present disclosure;

fig. 2 is a block diagram of a sterilization and disinfection apparatus according to some embodiments of the present disclosure; FIG. 3 is a block diagram of a cold plasma sterilization system for precision instruments, consumables according to some embodiments of the present disclosure;

FIG. 4 is an exemplary flow chart of a method of cold plasma sterilization for precision instruments, consumables according to some embodiments of the present disclosure;

FIG. 5 is an exemplary flow chart of a method of analyte analysis according to some embodiments of the present disclosure;

FIG. 6A is an image of an object to be treated according to some embodiments of the present disclosure;

FIG. 6B is an image of an object to be processed with object information according to some embodiments of the present disclosure;

fig. 6C is an image of an object to be processed with a focus area according to some embodiments of the present disclosure.

Detailed Description

In order to more clearly illustrate the technical solutions of the embodiments of the present specification, the drawings that are required to be used in the description of the embodiments will be briefly described below. It is apparent that the drawings in the following description are only some examples or embodiments of the present specification, and it is possible for those of ordinary skill in the art to apply the present specification to other similar situations according to the drawings without inventive effort. Unless otherwise apparent from the context of the language or otherwise specified, like reference numerals in the figures refer to like structures or operations.

It will be appreciated that "system," "apparatus," "unit" and/or "module" as used herein is one method for distinguishing between different components, elements, parts, portions or assemblies at different levels. However, if other words can achieve the same purpose, the words can be replaced by other expressions.

As used in this specification and the claims, the terms "a," "an," "the," and/or "the" are not specific to a singular, but may include a plurality, unless the context clearly dictates otherwise. In general, the terms "comprises" and "comprising" merely indicate that the steps and elements are explicitly identified, and they do not constitute an exclusive list, as other steps or elements may be included in a method or apparatus.

A flowchart is used in this specification to describe the operations performed by the system according to embodiments of the present specification. It should be appreciated that the preceding or following operations are not necessarily performed in order precisely. Rather, the steps may be processed in reverse order or simultaneously. Also, other operations may be added to or removed from these processes.

Fig. 1 is a schematic view of an application scenario of a cold plasma sterilization system for precision instruments, consumables according to some embodiments of the present disclosure.

In some embodiments, the application scenario 100 of the cold plasma sterilization and disinfection system for precision instruments, consumables may include a sterilization and disinfection apparatus 110, a network 120, a user terminal 130, a controller 140, a storage device 150, and an object to be treated 160.

In some embodiments, one or more components of the application scenario 100 may be connected and/or in communication with each other via a network 120 (e.g., a wireless connection, a wired connection, or a combination thereof). As shown in fig. 1, controller 140 may be connected to storage device 150 via network 120. For another example, the controller 140 may be connected to the sterilization and disinfection unit 110 through the network 120.

The sterilization and disinfection device 110 may be a sterilization and disinfection device using cold plasma for precision instruments and consumables according to some embodiments of the present disclosure. The sterilization and disinfection device 110 may be used to perform a sterilization and disinfection process on the object to be treated 160. So that the treated object 160 satisfies the corresponding use standard. For example, the sterilization and disinfection unit 110 may be used to disinfect medical instruments so that the treated medical instruments may be reused. In some embodiments, the sterilization and disinfection device 110 may be communicatively connected to the controller 140, where the controller 140 may be used as a controller of the sterilization and disinfection device 110 to control various devices within the sterilization and disinfection device 110 to perform a method of sterilizing and disinfecting precision instruments and consumables using cold plasma according to some embodiments of the present disclosure.

In some embodiments, the sterilization and disinfection device 110 and its related components (e.g., the controller 140) may be integrated in a portable closed sterilization case, which may generate cold plasma internally during the sterilization and disinfection device 110 to perform sterilization and disinfection operations on the precision instruments and consumables placed in the portable closed sterilization case.

The network 120 may connect components of the application scenario 100 and/or external resources. Network 120 enables communication between the various components and with external resources to facilitate the exchange of data and/or information. The network may be a local area network, a wide area network, the internet, etc., and may be a combination of various network structures.

User terminal 130 refers to one or more user terminals or software used by a user. User terminal 130 may include a smart phone 130-1, a tablet computer 130-2, a laptop computer 130-3, a desktop computer 130-4, and the like. In some embodiments, the user terminal 130 is connected to the controller 140 through the network 120, and may be used to display the processing result of the controller 140, for example, the user terminal 130 may receive, through the network 120, parameters of the controller 140 for performing sterilization and disinfection, a disinfection effect, and the like.

The controller 140 may be used to process data and/or information from at least one component of the application scenario 100 (e.g., the sterilization and disinfection device 110, the user terminal 130, the storage device 150) or an external data source (e.g., a cloud data center). The controller 140 may execute program instructions based on such data, information, and/or processing results to perform one or more of the functions described herein. For example, the controller 140 can analyze and process information about the object to be treated 160 acquired by the sterilization and disinfection device 110.

In some embodiments, the controller 140 may be a single processor or a group of processors. The processor complex may be centralized or distributed (e.g., controller 140 may be a distributed system), whether dedicated, or serviced concurrently by other devices or systems. In some embodiments, the controller 140 may contain one or more sub-processing devices (e.g., single-core processing devices or multi-core processing devices). By way of example only, the controller 140 may include a Central Processing Unit (CPU), an Application Specific Integrated Circuit (ASIC), the like, or any combination thereof. In some embodiments, the controller 140 may be integrated into the sterilization and disinfection device 110 as a controller for the sterilization and disinfection device 110.

In some embodiments, the controller 140 may be connected to the network 120 locally or remotely from the network 120. In some embodiments, the controller 140 may be implemented on a cloud platform. For example only, the cloud platform may include a private cloud, a public cloud, a hybrid cloud, a community cloud, a distributed cloud, an internal cloud, a multi-layer cloud, or the like, or any combination thereof.

Storage device 150 may be used to store data and/or instructions. In some embodiments, the storage device 150 may store data and/or instructions that the controller 140 uses to perform or use to accomplish the exemplary methods described in this specification. In some embodiments, the storage device 150 may be connected to the network 120 to communicate with one or more components of the sterilization and disinfection system 100 (e.g., the sterilization and disinfection unit 110) for delicate instruments, consumables with cold plasma.

The object to be treated 160 may refer to an object to be subjected to the sterilization and disinfection method shown in some embodiments of the present specification. In some embodiments, the object to be treated 160 may be a device to be sterilized that can be placed into the sterilization and disinfection unit 110. For example, the object to be treated 160 may be a precision instrument, consumable, or the like, to be sterilized. Illustratively, the treatment object 160 may be a post-use medical device (e.g., hemostat, etc.). In some embodiments, the object to be treated 160 may be pre-treated before performing the plasma sterilization based on the sterilization and disinfection apparatus 110. For example, the used hemostatic forceps may be subjected to a preliminary sterilization treatment by a sterilization means such as a sterilizing liquid to remove blood stains in the hemostatic forceps, and the hemostatic forceps after the pretreatment may be fed into the sterilization and disinfection device 110 to perform plasma sterilization and disinfection.

Fig. 2 is a schematic view of a sterilization and disinfection apparatus according to some embodiments of the present disclosure.

As shown in fig. 2, the sterilization and disinfection apparatus 110 may include a sterilization treatment chamber 111 and a chamber body 112, a plasma generation electrode 113, a detection device 114, a power supply 115, and a controller 140.

The sterilization treatment chamber 111 may be a main execution device of the sterilization and disinfection apparatus 110, and may be used to perform sterilization treatment on the object 160 based on cold plasma. For example, the sterilization treatment house 111 may be the aforementioned portable closed type sterilization box, and the respective devices of the sterilization and disinfection apparatus 110 may be integrally provided in the sterilization treatment house 111. In operation, the object to be treated 160 may be placed in the closed space (the chamber body 112) inside the sterilization chamber 111, and the sterilization chamber 111 may release cold plasma into the closed space to contact the cold plasma with the object to be treated 160, thereby killing viruses and bacteria adhering to the surface of the object to be treated 160.

The bin body 112 may be a closed space formed by the sterilizing treatment bin 111 when in operation. When the sterilization and disinfection treatment is performed, the plasma generating electrode 11 can continuously release cold plasma into the bin body 112, so that the cold plasma contacts with the to-be-treated object 160 placed in the bin body 111, and the sterilization and disinfection treatment is performed on the to-be-treated object 160.

The plasma generating electrode 113 may be used to generate cold plasma and be released into the cartridge body 112. For example, the low temperature plasma generating electrode 113 may be disposed inside the bin body 112, and cold plasma may be released to the surroundings to escape with the cold plasma to fill the bin body 112 when the low temperature plasma generating electrode 113 is operated. In some embodiments, the amount of cold plasma released per unit time by the plasma-generating electrode 113 is related to the internal electric field strength of the plasma-generating electrode 113. When the electric power supplied to the electric field in the plasma generating electrode 113 is increased, the amount of cold plasma released per unit time of the plasma generating electrode 113 can be increased.

The detection device 114 may be used to sense relevant parameters within the sterilization and disinfection unit 110. In some embodiments, the specific composition of the detection device 114 may be related to the specific data that needs to be detected. As shown in fig. 2, the detection device 114 may include an infrared ranging detection device 1141, a first image capturing device 1142, and a second image capturing device 1143.

The infrared ranging detection device 1141 may include at least two infrared light panels and an infrared receiving device. In some embodiments, the infrared ranging detection device 1141 may determine the exposed surface area and volume of the object 160 by detecting the distance of each detection point on the surface of the object 160. For more details regarding determining the exposed surface area and volume of the treatment object 160, see the relevant description of step 410.

The first image capturing apparatus 1142 may be a common image capturing apparatus, and the first image capturing apparatus 1142 may be used to acquire an image of the object to be processed. The image of the objects to be processed may be a photograph of the interior of the bin 112 containing each object to be processed. The object image to be processed can be used for confirming object information of the object to be processed and key areas. For more information on items of treatment and the areas of emphasis, see fig. 5 and its associated description.

The second imaging device 1143 may be an infrared thermal imaging device. The second camera 1143 may acquire an evaluation image within the bin 112, where the evaluation image may include temperature information for various locations of the bin 112, which may be used to determine the disinfection effect of the disinfection process.

The power source 115 may be integrally disposed within the sterilization treatment house 111 and in communication with an external power source for providing electrical power to one or more components of the sterilization and disinfection unit 110. In some embodiments, a switch button may be provided on the power supply to activate and/or deactivate the sterilization device 110. In some embodiments, the controller 140 may control the supply voltage of the power supply 115 to control the operating power of the various components. For example, the controller 140 may control a power supply voltage of the power supply 115 to supply power to the plasma generating electrode 113 to adjust an internal electric field intensity of the plasma generating electrode 113, thereby changing a cold plasma discharge amount per unit time.

In some embodiments, the sterilization and disinfection device 110 may further include a vacuum pump 116, where the vacuum pump 116 may be integrally disposed inside the sterilization and disinfection chamber 111, and the chamber body 112 is connected, and may be used to exhaust air in the chamber body 112 to create a vacuum environment, so as to improve the efficiency of the sterilization and disinfection process.

The controller 140 may be integrally disposed within the sterilization treatment facility 111 and communicatively coupled to one or more components of the sterilization and disinfection unit 110 to control the operational status of the various devices. For example, the controller may control the nozzle 111 to perform a sterilization process on the object to be processed 160. For another example, the controller may control the detection device 114 (e.g., the first image capturing device 1142) to capture an image of the object to be processed 160.

In some embodiments, the sterilization and disinfection device 110 may further include a movable nozzle 118, and the movable nozzle 118 may be in communication with a portion of the plasma-generating electrode 113 to release cold plasma generated at the plasma-generating electrode 113 at a fixed point. In operation, the movable nozzle 118 may move within the cartridge body 112 and release cold plasma at a fixed point to sterilize localized areas and/or equilibrate the concentration of cold plasma within the cartridge body 112.

At the time of sterilization and disinfection treatment, cold plasma discharged from the plasma generating electrode 113 tends to concentrate at the plasma generating electrode 113, possibly resulting in uneven concentration of cold plasma in the chamber 112. Thus, as shown in FIG. 2, the cartridge body 112 can further include a rotating platform 1121. The rotating platform 1121 may be a tray, a rack, or the like for holding the object 160 to be processed. The rotating platform 1121 may be rotated during the sterilization process to uniformly distribute the cold plasma over the object to be treated 160.

In some embodiments, the sterilization and disinfection device 110 may be activated after the power supply 115 is turned on, so that the vacuum pump 116 draws air from the cabin 112 to make the cabin 112 in a vacuum state. After the worker inserts the object 160, the sensor 113 may detect the relevant parameter of the object 160. The controller 140 may determine the exposed surface area and volume of the object 160 based on the parameters associated with the object 160. And determining sterilization parameters according to the exposed surface area and the volume, wherein the sterilization parameters are operation parameters of various equipment during sterilization treatment, and the sterilization parameters comprise time parameters and rotation parameters. And finally, controlling each device to sterilize and disinfect the object to be treated according to the sterilization and disinfection parameters.

Fig. 3 is a block diagram of a cold plasma sterilization system for precision instruments, consumables according to some embodiments of the present disclosure. In some embodiments, the cold plasma sterilization and disinfection system 300 for precision instruments, consumables may include a detection module 310, a calculation module 320, and an execution module 330.

In some embodiments, the detection module 310 may be used to obtain the exposed surface area and volume of the object to be treated. For more details on the exposed surface area and volume, see step 410 and its associated description.

In some embodiments, the computing module 320 may determine sterilization and disinfection parameters based on the exposed surface area and volume; the sterilization and disinfection parameters can be operation parameters of the sterilization treatment bin and the plasma generation electrode during sterilization and disinfection treatment, and the sterilization and disinfection parameters at least comprise time parameters of the plasma generation electrode and rotation parameters of the sterilization treatment bin. For more details regarding determining sterilization parameters, see step 420 and its associated description.

In some embodiments, the execution module 330 controls the sterilization treatment chamber and the plasma generation electrode to perform a sterilization treatment on the object to be treated according to the sterilization and disinfection parameters. For more details regarding the sterilization process, see step 430 and its associated description.

In some embodiments, the detection module 310 may be used to acquire an image of the object to be processed. The object image can be used for determining object information of the object to be processed.

In some embodiments, the computing module 320 may be further configured to determine, according to the item information and the image of the object to be processed, a key area of the object to be processed that needs to be sterilized; and determining the sterilization position of the movable nozzle based on the key area. The execution module 330 may also be used to control the movable nozzle to move to a sterilization position and to control the plasma generator apparatus device to perform a sterilization and disinfection process based on the sterilization and disinfection parameters. For more details on the key areas, see the relevant description of fig. 5.

In some embodiments, the sterilization and disinfection system 300 for precision instruments and consumables using cold plasma may further include an evaluation module 340, wherein the evaluation module 340 may be configured to obtain an evaluation image of the sterilization treatment cartridge after the sterilization and disinfection treatment; based on the evaluation image, a sterilizing effect of the sterilizing process performed on the sterilizing process cartridge is determined. For more on determining the evaluation image, the killing effect, see step 440, step 450 and their associated description.

Some embodiments of the present description also provide a computer-readable storage medium. The storage medium stores computer instructions, and after the computer reads the computer instructions in the storage medium, the computer executes the sterilization method of the cold plasma for the precision instruments and consumable materials provided by the embodiment of the specification.

It should be noted that the above description of the sterilization and disinfection system and its modules for precision instruments and consumables using cold plasma is for convenience of description only and is not intended to limit the present description to the scope of the illustrated embodiments. It will be appreciated by those skilled in the art that, given the principles of the system, various modules may be combined arbitrarily or a subsystem may be constructed in connection with other modules without departing from such principles. In some embodiments, the detection module 310, the calculation module 320, the execution module 330, and the evaluation module 340 disclosed in fig. 3 may be different modules in one system, or may be one module to implement the functions of two or more modules described above. For example, each module may share one memory module, or each module may have a respective memory module. Such variations are within the scope of the present description.

FIG. 4 is an exemplary flow chart of a method of cold plasma sterilization for precision instruments, consumables according to some embodiments of the present disclosure. In some embodiments, the process 400 may be performed by the controller 140 or the cold plasma sterilization and disinfection system 300 for precision instruments, consumables based on the sterilization and disinfection device 110.

As shown in fig. 4, the process 400 includes the steps of:

in step 410, the exposed surface area and volume of the object to be treated are obtained.

The exposed surface area may refer to the surface area of the object to be treated that is not occluded. For example, the exposed surface area may refer to the area of the object to be treated exposed to the air containing the plasma after the object to be treated is placed in the sterilization treatment chamber. For another example, the sterilization treatment chamber is generally provided with a tray on which the object to be treated is placed, and the area of the object to be treated, which is not in contact with the tray, may be exposed surface area.

In some embodiments, detection module 210 may determine the exposed surface area and volume based on the detection results of a sensor (e.g., infrared ranging detection device 1141). The infrared ranging detection device 1141 may be disposed inside the bin body 112, emit infrared rays to the object to be processed 160 through two infrared light plates, and receive the reflected infrared rays by the infrared receiving device, thereby determining distances between the infrared receiving device and respective detection points on the surface of the object to be processed 160. Thereby determining the exposed surface area and volume of the object to be treated 160. For example, the infrared ranging detection device 1141 may determine the height of each detection point on the surface of the object to be processed 160 according to its position and the distance from each detection point on the surface of the object to be processed 160, so as to model the surface of the object to be processed 160, and further determine the exposed surface area and volume of the object to be processed 160.

In some embodiments, the detection device 114 may include a three-dimensional camera that can acquire depth information, which can be disposed within the sterilization and disinfection unit 110 (e.g., above the bin 112), and which can acquire depth information of the object to be treated and determine the exposed surface area and volume based on the depth information.

Step 420, determining sterilization and disinfection parameters according to the exposed surface area and the volume.

The sterilization parameters are the operation parameters of the sterilization treatment bin when participating in the sterilization treatment. In some embodiments, the sterilization and disinfection parameters include at least a time parameter for releasing the cold plasma and a rotation parameter of the object to be treated within the sterilization treatment chamber.

The time parameter may reflect the duration of the sterilization process. In some embodiments, the time parameter may relate to the exposed surface area and volume of the object to be treated. Wherein the greater the exposed surface area and volume, the longer the duration of the sterilization and disinfection process.

The rotation parameter may reflect the rotation of the object to be processed within the housing 112. For example, the rotation parameters may include parameters related to rotational speed, acceleration, etc. of the rotating platform (e.g., rotating platform 1121).

It should be appreciated that the surface area per unit volume can be determined based on the exposed surface area and volume, and that the larger the surface area per unit volume, the longer it takes for the cold plasma to fully contact the surface of the object 160 to be treated, and the lower the rotational speed.

In some embodiments, the sterilization and disinfection parameters further comprise a power parameter of the plasma-generating electrode. Wherein the power parameter is related to the electric field strength of the plasma generating electrode and can be used for controlling the release amount of cold plasma per unit time. For example, the power parameter may reflect the power supply of the power supply voltage of the plasma-generating electrode.

In some embodiments, the power parameter may be determined based on the actual desired amount of cold plasma released per unit time. For example, when the exposed surface area and volume of the object to be treated are large, more cold plasma is required to achieve sterilization. The power parameter can thus be increased to release more cold plasma.

In some embodiments, the power parameter may also affect other operating parameters (e.g., time parameters). For example, for Bacillus subtilis black variant spores, the plasma-generating electrode may require 60 minutes of sterilization if it is held at 50 watts, and only 5 minutes of sterilization if it is held at 200 watts. In some embodiments, the power parameter may also be calculated inversely based on the actual desired plasma concentration. I.e. the device power of the plasma-generating electrode that can sustain the plasma concentration is determined from the plasma concentration.

In some embodiments, the computing module 220 may preset a plurality of sterilization and disinfection policies, each sterilization and disinfection policy including a range of applicability of the exposed surface area and volume and corresponding preset sterilization and disinfection parameters. When the detected exposed surface area and volume meet a certain application range, a corresponding sterilization strategy can be adopted, and the corresponding preset sterilization parameter determination rate is the sterilization parameter of the plasma generating electrode. For example, the sterilization and disinfection strategy may involve the need to maintain 50 watts of power for 60 minutes of sterilization and disinfection of the treatment object within 0.01 square meters of exposed surface area. The parameters of the sterilization and disinfection strategy may be used as the sterilization and disinfection parameters of the object to be treated 160 when the parameters of the object to be treated 160 meet the requirements of the sterilization and disinfection strategy.

And 430, controlling the sterilization treatment bin to carry out sterilization treatment on the objects to be treated according to the sterilization and disinfection parameters.

In some embodiments, the controller 140 may determine parameters of the respective devices according to the sterilization and disinfection parameters and transmit the parameters to the corresponding devices. For example, the power supplied to each plasma-generating electrode and the amount of plasma released may be determined according to a power parameter (e.g., total power), and the power supply may be controlled to supply power to each plasma-generating electrode according to the power supplied.

The cold plasma provided by some embodiments based on the specification is used for sterilizing and disinfecting precision instruments and consumable materials. Corresponding sterilization parameters can be adjusted according to the exposed surface area and volume of the object to be treated, so that the sterilization operation can further meet the sterilization requirement of the object to be treated.

In some embodiments, the biocidal effect can be evaluated after the biocidal treatment is completed. As shown in fig. 3, the process 300 may further include the following steps for assessing the effectiveness of killing;

step 440, acquiring an evaluation image of the sterilization treatment bin after the sterilization treatment.

The evaluation image may refer to an image directly or indirectly reflecting the distribution of the plasma in the sterilization treatment chamber. In some embodiments, where the temperature of the cold plasma is different from the room temperature, the evaluation image may be a temperature image acquired by a second imaging device 1143 (e.g., an infrared thermal imaging device). In the temperature image, the temperature of each region can be characterized by the color of the region. For example, red may represent a high temperature and blue may represent a low temperature.

In some embodiments, the sterilization treatment bin may be divided into a plurality of local areas based on the foregoing evaluation image. The local area may be divided according to actual situations. For example, the inner space of the sterilizing compartment may be divided into a plurality of partial areas according to positions. For another example, the plasma discharge position (e.g., the position of the nozzle) may be defined as a plurality of partial regions along the discharge direction.

Step 450, determining the disinfection effect of the disinfection treatment performed by the disinfection treatment bin based on the evaluation image.

In some embodiments, the cold plasma concentration of each localized region in the cartridge body 112 can be determined based on the evaluation image, and the sterilization effect of the sterilization and disinfection process performed by the sterilization treatment cartridge can be determined based on the cold plasma concentration. When the temperature of a certain local area in the evaluation image is close to the room temperature, the influence of cold plasma on the area can be determined to be smaller, and the cold plasma concentration of the local area is lower; a region temperature close to the cold plasma temperature (e.g., the temperature of the cold plasma) indicates a higher plasma concentration in the region.

In some embodiments, the temperature of the local area may be determined from the image by evaluation. For example, the local temperatures of the local areas in the sterilization treatment bin can be determined according to the evaluation image; and determining the killing effect according to the local temperature of each local area. Wherein the local temperature may be an average temperature of the region, which may be determined from the color of the evaluation image.

In some embodiments, the killing effect may be determined from a relationship between the temperature of the localized region and the cold plasma temperature and room temperature. When the temperature of the local area is closer to the cold plasma temperature, the area can be considered to be sufficiently sterilized. When the temperature of the area is closer to room temperature, it can be considered that the sterilization and disinfection of the area are insufficient. In some embodiments, the killing effect may be characterized by a killing scale. May be determined by comparing the temperature of the local area to a temperature threshold corresponding to the disinfection level.

In some embodiments, a region where the temperature of the local region satisfies a preset condition may be determined as the sterilization weak region based on the temperature of the local region. The concentration of the plasma in the weak area may not meet the disinfection requirement, and when the object to be treated passes through the local area, the plasma on the surface of the object to be treated may be unevenly distributed, thereby affecting the disinfection effect. In some embodiments, the preset condition may be a temperature threshold, where the temperature of the low temperature plasma may be less than the temperature threshold, the temperature of the temperature threshold is less than room temperature, and when the temperature of the local area is greater than the temperature threshold, it is determined that the preset condition is satisfied.

In some embodiments, the movable nozzle can be controlled to release plasma to the part of the object to be treated, which is positioned in the weak area for sterilization after the sterilization and disinfection treatment is finished, so that the secondary sterilization of the weak area for sterilization can be realized. Wherein the time of sterilization of the area of the sterilization of the movable nozzle is related to the temperature difference between the temperature of the area of the sterilization and the temperature of the plasma. The greater the temperature difference, the longer the disinfection time.

It should be noted that the above description of the process 400 is for purposes of illustration and description only, and is not intended to limit the scope of applicability of the present disclosure. Various modifications and changes may be made to the flight control of the drone under the guidance of this specification by those skilled in the art. However, such modifications and variations are still within the scope of the present description.

FIG. 5 is an exemplary flow chart of a method of analyte analysis according to some embodiments of the present description. In some embodiments, the process 500 may be performed based on the controller 140. As shown in fig. 5, the process 500 may include the steps of:

step 510, acquiring an image of the object to be processed.

The image of the object to be treated can be the image information of the object to be treated placed in the sterilizing treatment bin. The image of the object to be treated can reflect the placement condition of the object to be treated in the sterilizing treatment bin. In some embodiments, the object image may reflect the placement of each object. For example, when a plurality of objects to be treated are placed in the sterilizing chamber each time, the image of the objects to be treated can reflect the placement of the respective objects to be treated in the sterilizing chamber.

In some embodiments, the object image may be acquired by the first imaging device 1142. For example, the first image capturing device 1142 may be disposed above the sterilization treatment chamber and directed toward the object to be treated to acquire a top view of the object to be treated as an image of the object to be treated.

Step 520, determining article information of the object to be processed according to the image of the object to be processed.

The item information may reflect information about each object to be processed. The item information may include the type of item to be treated.

In some embodiments, the item information may be determined by manually identifying the image to be processed. For example, when the object to be treated is placed in the sterilization treatment bin, an image of the object to be treated may be presented to the worker so that the worker determines the object information (such as the type of the object to be treated) through the interactive operation.

In some embodiments, the item information may be determined by identifying the image to be processed through the first identification model. In some embodiments, the treatment object image may be processed based on the first recognition model to determine item information of the treatment object. Wherein the first recognition model may be a trained machine learning model. For example, the first recognition model may be a trained convolutional neural network (Convolutional Neural Networks, CNN) model.

The input of the first recognition model may be an object image to be processed and the output may include the processed object image to be recognized. The processed image of the object to be identified comprises an identification frame of each object to be processed and a corresponding type. An identification frame and a corresponding type of each object to be processed in the image to be processed. The identification frame can be a rectangular frame body which is presented in the image, and the identification frame can reflect the object information of the image in the frame body. For example, the type of the object to be processed may be represented by information (e.g., color, frame line, remark information, etc.) related to the identification frame.

For example, the controller may input the object image 610 to be processed as shown in fig. 6A into a first recognition model, wherein the object image 600 includes only the surgical scissors 1601 and one surgical knife 1602. The processed object image 620 shown in fig. 6B is obtained through the first recognition model processing.

As shown in fig. 6B, in the processed object image 620, the object information of the surgical scissors 1601 can be identified by the identification box 1611. Wherein, a label 1631 may be provided on the identification frame 1611, and the label 1631 may indicate the type of the surgical scissors 1601 in a text form. The item information of the scalpel 1602 can be identified by an identification box 1612. Wherein a label 1632 may be provided on the identification frame 1612, the label 1632 may indicate the type of the scalpel 1602 in text form.

In some embodiments, an initial first recognition model may be trained based on training data to determine a first recognition model. Wherein the initial first recognition model may be a first recognition model with no parameters set.

The training data of the initial first recognition model may include a first training sample and a first sample tag. The first training sample may be a sample image containing various sample items. The first sample tag may be item information with the sample item. Wherein, the article information can be embodied through the identification frame of manual marking. In training the initial first recognition model, a first training sample may be input to the initial first recognition model to obtain a model output. And constructing a loss function according to the model output and the first sample label, and iterating the parameters of the initial first recognition model until training is completed. And taking the trained initial first recognition model as a first recognition model. The training completion may include cases that the iteration number exceeds a threshold, error convergence of the model output and the first sample label, and the like.

In some embodiments, the item information may also include a status of placement of the item to be treated. The placement state may include an overlapping condition between objects to be processed. In some embodiments, the overlap condition may be determined based on the overlap rate between the identification boxes. As shown in fig. 6B, if there is an overlap between the identification frames 1611 and 1622, there is a possibility of an overlap between the corresponding objects to be processed, and the overlap between the objects to be processed may be determined according to the overlap ratio between the identification frames. The placement state may also include a self-placement state of the object to be treated. For example, for surgical shears, its own resting state may include the angle of opening of the scissor head. In some embodiments, the self-pose state may be determined based on the type of item and the image of the item to be processed. For example, the object image to be processed may be compared with a plurality of preset placement states of the object type, and the placement state with the highest similarity may be used as the self placement state.

In some embodiments, it may be determined whether the object to be processed satisfies the corresponding placement rule based on the placement state. The placement rule may be a rule that the placement state of the object to be treated should be satisfied when the object to be treated is sterilized. For example, placement rules may include that there may not be overlap between the objects to be treated, nor that the objects themselves be allowed to appear in unexposed areas (e.g., closed surgical scissors). When the objects to be treated meet the corresponding arrangement rules, sterilizing the objects to be treated according to the sterilization parameters. And when the object to be processed does not meet the corresponding placement rule, generating prompt information. The prompt information can be presented to the staff to remind the staff to put the object to be processed again.

In some embodiments, the process 500 may further analyze the image to be processed to determine the key areas that require sterilization and disinfection. As shown in fig. 5, the process 500 may further include the steps of:

and 530, determining a key area of the object to be treated, which needs sterilization and disinfection treatment, according to the object information and the object image to be treated.

The key area can refer to an area where bacteria are easy to accumulate in the use process of the object to be treated. For example, the key region may include a region where the object to be treated is in direct contact with other objects. Illustratively, the accent area may include a surgical scissors, a knife head area of a surgical knife, and a grip area. In some embodiments, the accent areas may also include areas with higher disinfection requirements. For example, the emphasized region may include a region that is in direct contact with the human body (e.g., a needle, etc.). For another example, when the object to be treated is a tube-like cavity product, the important area may be inside the tube orifice of the tube-like cavity product.

In some embodiments, the focal region may be determined according to the type of object to be processed. For example, the key area of the type of the object to be processed can be determined according to a preset rule according to the type of the object to be processed. When the object to be treated is determined to be a scalpel, the key area of the object to be treated can be determined to be a cutting edge according to a preset rule. After the controller identifies the object information of the object to be processed, the key area can be determined according to the type of the object to be processed and marked in the image to be processed.

In some embodiments, the key area may further perform recognition determination on the processed image of the object to be recognized through the second recognition model. Wherein the second recognition model may be a trained machine learning model. For example, the second recognition model may be a trained CNN model.

In some embodiments, the input of the second recognition model may be recognition determination of the processed object image, and the output may be a target object image, where the target object image may include a key region of each object to be processed in addition to a recognition frame and a type of each object to be recognized. The display mode of the identification frame of the key area in the object to be identified can be different from the display mode of the identification frame of the object to be identified. For example, the identification frame of the item information may be a rectangular solid line, and the identification frame of the key region may be a circular dotted line.

For example, the image to be processed 620 shown in fig. 6B may be input into a second recognition model to determine the image to be recognized 630 after the recognition of the key region as shown in fig. 6C.

As shown in fig. 6C, the image 630 to be recognized after the emphasis region recognition may include a emphasis region recognition frame 1621 of the surgical scissors 1601 and a emphasis region recognition frame 1622 of the surgical knife 1602. The important region identification frame may describe a region defined by the identification frame as an important region.

In some embodiments, the initial second recognition model may be trained based on training data to determine the second recognition model. Wherein the initial second recognition model may be the first recognition model with no parameters set.

The training data of the initial second recognition model may include a second training sample and a second sample tag. The second training sample may be a sample image (for example, may be a sample image processed by the first recognition model) containing the sample article with article information. The second sample label may be a sample image with a region of emphasis. The key areas can be represented by the manually marked identification boxes. While training the initial second recognition model, a second training sample may be input to the initial second recognition model to obtain a model output. And constructing a loss function according to the model output and the second sample label, and iterating the parameters of the initial second recognition model until training is completed. And taking the trained initial second recognition model as a second recognition model.

Step 540, determining the sterilization position of the movable nozzle based on the focal region.

The sterilization position of the movable nozzle may refer to the position of the movable nozzle to release the plasma.

In some embodiments, the controller may determine the sterilization location based on the accent area. For example, a sterilization position that can completely cover the highlight region may be determined as the sterilization position based on the movable nozzle and the highlight region.

Step 550, controlling the movable nozzle to move to the sterilization position, and performing sterilization and disinfection treatment based on the sterilization and disinfection parameters.

To thoroughly sterilize the object, the controller 140 may control the rotation of the rotation stage 1111 based on sterilization parameters, so that the plasma uniformly covers the surface of the object to be sterilized. Then, the rotation is stopped, the movable nozzle is controlled to move to the sterilization position, and the fixed-point sterilization and disinfection treatment is carried out on the key area of each object to be treated. The sterilization and disinfection parameters may also include the duration of the spot sterilization and disinfection process. For example, the surgical shears may be rotated first for 30 minutes of overall sterilization (i.e., the surgical shears are rotated within a plasma filled sterilization chamber), and then the blade head area is subjected to 5 minutes of spot sterilization.

In some embodiments, when the fixed-point sterilization treatment is performed on the test tube type cavity type product, the movable nozzle can be controlled to move to the pipe orifice of the test tube type cavity type product, and the plasma generating electrode is controlled to perform the fixed-point sterilization treatment on the spraying plasma inside the pipe orifice based on the sterilization parameters. Wherein, the sterilization and disinfection parameters comprise the treatment time of fixed-point sterilization and disinfection treatment, and the treatment time is related to the area of the inner wall of the test tube. The larger the inner wall area, the longer the treatment time.

Based on the analysis method for the to-be-treated object provided by some embodiments of the present disclosure, the sterilization and disinfection parameters can be further adapted to the actual situation of the to-be-treated object, so as to improve the disinfection effect of the to-be-treated object.

While the basic concepts have been described above, it will be apparent to those skilled in the art that the foregoing detailed disclosure is by way of example only and is not intended to be limiting. Although not explicitly described herein, various modifications, improvements, and adaptations to the present disclosure may occur to one skilled in the art. Such modifications, improvements, and modifications are intended to be suggested within this specification, and therefore, such modifications, improvements, and modifications are intended to be included within the spirit and scope of the exemplary embodiments of the present invention.

Meanwhile, the specification uses specific words to describe the embodiments of the specification. Reference to "one embodiment," "an embodiment," and/or "some embodiments" means that a particular feature, structure, or characteristic is associated with at least one embodiment of the present description. Thus, it should be emphasized and should be appreciated that two or more references to "an embodiment" or "one embodiment" or "an alternative embodiment" in various positions in this specification are not necessarily referring to the same embodiment. Furthermore, certain features, structures, or characteristics of one or more embodiments of the present description may be combined as suitable.

Furthermore, the order in which the elements and sequences are processed, the use of numerical letters, or other designations in the description are not intended to limit the order in which the processes and methods of the description are performed unless explicitly recited in the claims. While certain presently useful inventive embodiments have been discussed in the foregoing disclosure, by way of various examples, it is to be understood that such details are merely illustrative and that the appended claims are not limited to the disclosed embodiments, but, on the contrary, are intended to cover all modifications and equivalent arrangements included within the spirit and scope of the embodiments of the present disclosure. For example, while the system components described above may be implemented by hardware devices, they may also be implemented solely by software solutions, such as installing the described system on an existing server or mobile device.

Likewise, it should be noted that in order to simplify the presentation disclosed in this specification and thereby aid in understanding one or more inventive embodiments, various features are sometimes grouped together in a single embodiment, figure, or description thereof. This method of disclosure, however, is not intended to imply that more features than are presented in the claims are required for the present description. Indeed, less than all of the features of a single embodiment disclosed above.

In some embodiments, numbers describing the components, number of attributes are used, it being understood that such numbers being used in the description of embodiments are modified in some examples by the modifier "about," approximately, "or" substantially. Unless otherwise indicated, "about," "approximately," or "substantially" indicate that the number allows for a 20% variation. Accordingly, in some embodiments, numerical parameters set forth in the specification and claims are approximations that may vary depending upon the desired properties sought to be obtained by the individual embodiments. In some embodiments, the numerical parameters should take into account the specified significant digits and employ a method for preserving the general number of digits. Although the numerical ranges and parameters set forth herein are approximations that may be employed in some embodiments to confirm the breadth of the range, in particular embodiments, the setting of such numerical values is as precise as possible.

Each patent, patent application publication, and other material, such as articles, books, specifications, publications, documents, etc., referred to in this specification is incorporated herein by reference in its entirety. Except for application history documents that are inconsistent or conflicting with the content of this specification, documents that are currently or later attached to this specification in which the broadest scope of the claims to this specification is limited are also. It is noted that, if the description, definition, and/or use of a term in an attached material in this specification does not conform to or conflict with what is described in this specification, the description, definition, and/or use of the term in this specification controls.

Finally, it should be understood that the embodiments described in this specification are merely illustrative of the principles of the embodiments of this specification. Other variations are possible within the scope of this description. Thus, by way of example, and not limitation, alternative configurations of embodiments of the present specification may be considered as consistent with the teachings of the present specification. Accordingly, the embodiments of the present specification are not limited to only the embodiments explicitly described and depicted in the present specification.

Claims

1. A sterilization and disinfection device for precision instruments and consumable materials by cold plasma, which is characterized by comprising:

a sterilization treatment bin for performing sterilization treatment on an object to be treated based on cold plasma, wherein the sterilization treatment bin comprises a plasma generation electrode for releasing the cold plasma, and the plasma generation electrode comprises a movable nozzle for releasing the cold plasma; the first camera equipment is in communication connection with the controller and is used for shooting the object to be processed and obtaining an image of the object to be processed; and the controller is in communication connection with the sterilization treatment bin and is used for:

acquiring the exposed surface area and the volume of the object to be treated, wherein the exposed surface area refers to the surface area of the object to be treated which is not shielded;

Determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of the sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin; and

controlling the sterilization treatment bin to perform sterilization treatment on the object to be treated according to the sterilization and disinfection parameters;

the controller is further configured to:

acquiring the image of the object to be processed;

determining article information of the objects to be processed through a first recognition model according to the object to be processed, wherein the first recognition model is a machine learning model, the input of the first recognition model comprises the object to be processed image, the output comprises the processed object to be recognized image, the processed object to be recognized image comprises recognition frames and corresponding types of each object to be processed, the article information comprises the types of the objects to be processed and the placement states of the objects to be processed, the placement states comprise the overlapping condition among the objects to be processed and the placement state of the objects to be processed, and the overlapping condition is determined according to the overlapping rate among the recognition frames;

Determining a key area of the object to be processed, which is required to be sterilized and disinfected, through a second recognition model according to the object information and the object image to be processed, wherein the second recognition model is a machine learning model, the output of the second recognition model comprises a target object image to be processed, and the target object image comprises a recognition frame and a type of each object to be processed and the key area of each object to be processed;

determining a sterilization position of the movable nozzle based on the key area; and

and controlling the movable nozzle to move to the sterilization position, and performing sterilization and disinfection treatment based on the sterilization and disinfection parameters.

2. The sterilization and disinfection unit according to claim 1, further comprising:

the second camera equipment is used for shooting after sterilization and disinfection treatment to obtain an evaluation image of the sterilization treatment bin after the sterilization and disinfection treatment;

the controller is further configured to:

acquiring the evaluation image;

based on the evaluation image, a sterilizing effect of the sterilizing process performed on the sterilizing process cartridge is determined.

3. A sterilization and disinfection method of cold plasma for precision instruments and consumable materials, characterized in that the sterilization and disinfection method is applied to the sterilization and disinfection device of any one of claims 1-2, and the method comprises the following steps:

Acquiring the exposed surface area and the volume of an object to be treated, wherein the exposed surface area refers to the surface area of the object to be treated which is not shielded;

determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of a sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin; and

the method further comprises the steps of:

acquiring an image of an object to be processed;

determining the sterilization position of the movable nozzle based on the key area; and

4. A method of disinfecting according to claim 3, wherein the method further comprises:

acquiring an evaluation image of the sterilization treatment bin after sterilization treatment;

5. A sterilization and disinfection system for precision instruments and consumables by cold plasma, characterized in that the sterilization and disinfection system comprises:

the detection module is used for acquiring the exposed surface area and the volume of the object to be treated, wherein the exposed surface area refers to the surface area of the object to be treated which is not shielded;

A calculation module for determining sterilization and disinfection parameters according to the exposed surface area and the volume; the sterilization parameters are operation parameters of a sterilization treatment bin during sterilization treatment, and at least comprise time parameters for releasing the cold plasma and rotation parameters of the object to be treated in the sterilization treatment bin;

the computing module may also be for:

acquiring an image of an object to be processed;

the execution module is used for controlling the sterilization treatment bin to carry out sterilization treatment on the object to be treated according to the sterilization and disinfection parameters;

the execution module may also be to:

6. A computer readable storage medium storing computer instructions which, when read by a computer in the storage medium, perform the method of any one of claims 3-4.