CN115337694A - Medicine stock solution filter equipment who contains fine particle - Google Patents
Medicine stock solution filter equipment who contains fine particle Download PDFInfo
- Publication number
- CN115337694A CN115337694A CN202210988386.6A CN202210988386A CN115337694A CN 115337694 A CN115337694 A CN 115337694A CN 202210988386 A CN202210988386 A CN 202210988386A CN 115337694 A CN115337694 A CN 115337694A
- Authority
- CN
- China
- Prior art keywords
- filtering
- cavity
- carbon fiber
- filtered
- plate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 15
- 239000010419 fine particle Substances 0.000 title claims abstract description 14
- 229940079593 drug Drugs 0.000 title claims abstract description 12
- 239000011550 stock solution Substances 0.000 title claims abstract description 6
- 238000001914 filtration Methods 0.000 claims abstract description 39
- 238000004891 communication Methods 0.000 claims abstract description 8
- 238000000926 separation method Methods 0.000 claims abstract description 8
- 238000000746 purification Methods 0.000 claims abstract description 7
- 238000002955 isolation Methods 0.000 claims abstract description 6
- 238000010438 heat treatment Methods 0.000 claims description 61
- 229920000049 Carbon (fiber) Polymers 0.000 claims description 44
- 239000004917 carbon fiber Substances 0.000 claims description 44
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical group C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 claims description 44
- 239000004744 fabric Substances 0.000 claims description 39
- 238000003825 pressing Methods 0.000 claims description 35
- 229920005989 resin Polymers 0.000 claims description 32
- 239000011347 resin Substances 0.000 claims description 32
- 239000005341 toughened glass Substances 0.000 claims description 28
- 238000003475 lamination Methods 0.000 claims description 18
- 238000002844 melting Methods 0.000 claims description 18
- 230000008018 melting Effects 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 16
- -1 polytetrafluoroethylene Polymers 0.000 claims description 14
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 14
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 14
- 239000000243 solution Substances 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 229920006350 polyacrylonitrile resin Polymers 0.000 claims description 7
- 229920005990 polystyrene resin Polymers 0.000 claims description 7
- 238000012958 reprocessing Methods 0.000 claims description 6
- 239000012943 hotmelt Substances 0.000 claims description 3
- 238000011084 recovery Methods 0.000 abstract description 8
- 239000007788 liquid Substances 0.000 description 15
- 239000011148 porous material Substances 0.000 description 13
- 238000012545 processing Methods 0.000 description 8
- 238000005984 hydrogenation reaction Methods 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000009736 wetting Methods 0.000 description 3
- 239000007868 Raney catalyst Substances 0.000 description 2
- NPXOKRUENSOPAO-UHFFFAOYSA-N Raney nickel Chemical compound [Al].[Ni] NPXOKRUENSOPAO-UHFFFAOYSA-N 0.000 description 2
- 229910000564 Raney nickel Inorganic materials 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/11—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with bag, cage, hose, tube, sleeve or like filtering elements
- B01D29/13—Supported filter elements
- B01D29/15—Supported filter elements arranged for inward flow filtration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/11—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with bag, cage, hose, tube, sleeve or like filtering elements
- B01D29/111—Making filtering elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/50—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
- B01D29/52—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition in parallel connection
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/50—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
- B01D29/56—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition in series connection
- B01D29/58—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition in series connection arranged concentrically or coaxially
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D39/00—Filtering material for liquid or gaseous fluids
- B01D39/14—Other self-supporting filtering material ; Other filtering material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/06—Filter cloth, e.g. knitted, woven non-woven; self-supported material
- B01D2239/065—More than one layer present in the filtering material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/06—Filter cloth, e.g. knitted, woven non-woven; self-supported material
- B01D2239/065—More than one layer present in the filtering material
- B01D2239/0668—The layers being joined by heat or melt-bonding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/10—Filtering material manufacturing
Abstract
A drug stock solution filtering device containing fine particles comprises a cavity to be filtered, and a purifying cavity is arranged below the cavity to be filtered; a separation plate is arranged between the cavity to be filtered and the purification cavity, a plurality of communication holes are formed in the separation plate, a filtering cylinder is inserted in the communication holes, and the filtering cylinder is arranged in the cavity to be filtered; the filter cylinder comprises a support shell, and a filter screen is arranged on the outer side of the support shell; the support shell is provided with an annular fixed plate on one side of the purification cavity, and the end part of the filter screen is fixedly arranged between the annular fixed plate and the isolation plate. This application avoids blockking up, and the mode that adopts outer cup jointing can conveniently carry out the backwash to avoid it to take place to block up, and because the remaining raffinate after retrieving can directly be used, consequently, single rate of recovery is lower, but holistic circulation rate of recovery can obtain guaranteeing, and the pressure drop of recovery structure self is very low.
Description
Technical Field
The application relates to a medicine stoste filter equipment who contains fine particle.
Background
In the synthesis process of raw medicine, hydrogenation operation is sometimes needed, raney nickel is generally used as a catalyst in hydrogenation, and then hydrogenation operation is carried out, because the Raney used in the reaction process has a high specific surface area and a very small particle size, a common filtering mode firstly cannot play a role in recovering the Raney nickel and secondly is easy to cause the blockage of a filtering component, so that the early filtering effect is generally still available, but the blockage can be caused after the filtering component is used for a period of time, the filtering efficiency is reduced suddenly, and under the state, the filtering component is difficult to regenerate.
Disclosure of Invention
In order to solve the problems, the application discloses a drug stock solution filtering device containing fine particles, which comprises a cavity to be filtered, wherein a purifying cavity is arranged below the cavity to be filtered; a separation plate is arranged between the cavity to be filtered and the purification cavity, a plurality of communication holes are formed in the separation plate, a filtering cylinder is inserted in the communication holes, and the filtering cylinder is arranged in the cavity to be filtered; the filter cylinder comprises a support shell, and a filter screen is arranged on the outer side of the support shell; the support shell is provided with an annular fixed plate on one side of the purification cavity, and the end part of the filter screen is fixedly arranged between the annular fixed plate and the isolation plate. This application avoids blockking up, and the mode that adopts outer cup jointing can conveniently carry out the backwash to avoid it to take place to block up, and because the remaining raffinate after retrieving can directly be used, consequently, single rate of recovery is lower, but holistic circulation rate of recovery can obtain guaranteeing, and the pressure drop of recovery structure self is very low.
Preferably, an upper lead-in pipeline is arranged at the upper part of the filtering shell, and a side lead-out pipeline is arranged at the bottom of the isolation plate; a lower guide pipeline is arranged at the bottom of the purifying cavity.
Preferably, the filter screen comprises a first filter layer, a support layer and a second filter layer which are arranged from top to bottom in sequence.
Preferably, the first filter layer and the second filter layer are polytetrafluoroethylene filter membranes, and the support layer is a carbon fiber mesh layer. The utility model provides a carbon fiber net layer provides whole skeleton, and then both sides and middle part all set up polytetrafluoroethylene, and inside and outside both sides all form polytetrafluoroethylene filtration membrane, on its self wearability is good, the high basis of intensity, can also avoid taking place structural deformation.
Preferably, the filter screen is synthesized according to the following method:
mixing polytetrafluoroethylene resin, polyacrylonitrile resin and polystyrene resin to obtain mixed resin;
taking the carbon fiber mesh cloth as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth, wherein the lamination pressure is not lower than 15MPa, and the lamination time is not lower than 30min; in the case where the pressing pressure is maintained after the hot-melt pressing, the temperature is increased and then the heat treatment is performed.
Preferably, the device also comprises a mould, the carbon fiber mesh cloth is arranged in the middle of the mould, and the upper side and the lower side of the carbon fiber mesh cloth are respectively provided with mixed resin.
Preferably, the height of the support layer is 0.1-0.15mm, and the thickness of the first and second filter layers is 0.04-0.06mm.
Preferably, the mold comprises an annular shell, a fixed channel for fixing the carbon fiber mesh cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper tempered glass is arranged on the surface of the upper pressure plate, lower tempered glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper tempered glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower tempered glass; the number of the upper microwave generators and the lower microwave generators is 9.
Preferably, the hot melting and pressing utilizes an upper microwave generator and a lower microwave generator to heat, and the heating temperature is 300-350 ℃; the heat treatment temperature is 420-440 deg.C, and the time is 4-5min.
Preferably, after the pressing, the method also comprises a reprocessing process after the heat treatment, wherein the pressure is reduced to 0.5-1MPa, then the intermittent heating is carried out by utilizing an upper microwave generator and a lower microwave generator, the heating power is not lower than 300W, and the heating time and the heating interval are controlled so that the temperature is not higher than 200 ℃ and the time is 60-90s. This application forms holistic membrane structure earlier, then carries out intermittent type heating for carbon fiber net check cloth and mixed resin produce asynchronous deformation, further promotion pore structure's gradual change nature forms, thereby guarantees pore structure's stability.
This application can bring following beneficial effect:
1. this application avoids blockking up, and the mode that adopts outer cup jointing can conveniently carry out the backwash to avoid it to take place to block up, and because the remaining raffinate after retrieving can directly be used, consequently, although single rate of recovery is lower, holistic circulation rate of recovery can obtain guaranteeing, and the pressure drop of retrieving structure self is very low.
2. The utility model provides a carbon fiber net layer provides whole skeleton, and then both sides and middle part all set up polytetrafluoroethylene, and inside and outside both sides all form polytetrafluoroethylene filtration membrane, on its self wearability is good, the high basis of intensity, can also avoid taking place structural deformation.
3. This application forms holistic membrane structure earlier, then carries out intermittent type heating for carbon fiber net check cloth and mixed resin produce asynchronous deformation, further promotion pore structure's gradual change nature forms, thereby guarantees pore structure's stability.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
FIG. 1 is a schematic structural diagram of the present application;
FIG. 2 is a schematic structural view of a separator plate;
FIG. 3 is a schematic structural diagram of a filter screen;
fig. 4 is a schematic structural view of the mold.
Detailed Description
In order to clearly illustrate the technical features of the present solution, the present application will be explained in detail through the following embodiments.
As shown in fig. 1-4, a device for filtering drug stock solution containing fine particles comprises a chamber 1 to be filtered, and a purifying chamber 2 is arranged below the chamber 1 to be filtered; a separation plate 3 is arranged between the cavity 1 to be filtered and the purification cavity 2, a plurality of communication holes 4 are arranged on the separation plate 3, a filtering cylinder 5 is inserted in the communication holes 4, and the filtering cylinder 5 is arranged in the cavity 1 to be filtered; the filtering cylinder 5 comprises a supporting shell 6, and a filtering net 7 is arranged on the outer side of the supporting shell 6; the supporting shell 6 is provided with an annular fixing plate 8 at one side of the purifying cavity 2, and the end part of the filter screen 7 is fixedly arranged between the annular fixing plate 8 and the partition plate 3. An upper lead-in pipeline 9 is arranged at the upper part of the filtering shell 1, and a side lead-out pipeline 10 is arranged at the bottom of the isolation plate 3; a lower guide-out pipeline 11 is arranged at the bottom of the purifying cavity 2. The filter screen 7 comprises a first filter layer 12, a support layer 13 and a second filter layer 14 which are arranged from top to bottom in sequence. The first filter layer 12 and the second filter layer 14 are polytetrafluoroethylene filter membranes, and the support layer 13 is a carbon fiber mesh layer.
The filter screen is synthesized according to the following method:
mixing polytetrafluoroethylene resin, polyacrylonitrile resin and polystyrene resin to obtain mixed resin;
taking carbon fiber mesh cloth as a carrier, placing half of mixed resin into the range of the annular shell 15 and the lower pressing plate according to the capacity, then laying the carbon fiber mesh cloth, fixing the two sides of the carbon fiber mesh cloth by using a fixing channel 16, placing the other half of the mixed resin, and then carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth, wherein the lamination pressure is not lower than 15MPa, and the lamination time is not lower than 30min; in the case where the pressing pressure is maintained after the hot-melt pressing, the temperature is increased and then heat treatment is performed. The carbon fiber mesh cloth is arranged in the middle of the mold, and mixed resin is respectively arranged on the upper side and the lower side of the carbon fiber mesh cloth. The height of the support layer 13 is 0.1-0.15mm, and the thickness of the first and second filter layers 12 and 14 is 0.04-0.06mm. The mold comprises an annular shell 15, a fixed channel 16 for fixing carbon fiber gridding cloth is arranged in the middle of the annular shell 15, the outer side of the fixed channel 16 can be fixed in a clamping and stretching mode, an upper pressure plate 17 is arranged at the upper part of the annular shell 15, a lower pressure plate 18 is arranged at the lower part of the annular shell 15, upper tempered glass 19 is arranged on the surface of the upper pressure plate 17, lower tempered glass 20 is arranged on the surface of the lower pressure plate 18, a plurality of upper microwave generators 21 are uniformly distributed at the inner side of the upper pressure plate 17 relative to the upper tempered glass 19, and a plurality of lower microwave generators 22 are uniformly distributed at the inner side of the lower pressure plate 18 relative to the lower tempered glass 20; the number of the upper and lower microwave generators 21 and 22 is 9, the size of the upper and lower press plates 17 and 18 is 500mm by 500mm, and the heating power of the upper and lower microwave generators 21 and 22 is up to 500W. Heating by using an upper microwave generator 21 and a lower microwave generator 22 in a hot melting and pressing way to reach the heating temperature of 300-350 ℃; the heat treatment temperature is 420-440 deg.C, and the time is 4-5min. After the pressing, the method also comprises a reprocessing process after the heat treatment, wherein the pressure is reduced to 0.5-1MPa, then an upper microwave generator and a lower microwave generator are used for carrying out intermittent heating, the heating power is not lower than 300W, the heating time and the heating interval are controlled so that the temperature is not higher than 200 ℃ and the time is 60-90s. The upper pressing plate and the lower pressing plate are pressed in a piston cylinder mode and the like.
The filter screen is synthesized specifically as follows:
s1, mixing polytetrafluoroethylene resin, polyacrylonitrile resin and polystyrene resin to obtain mixed resin;
s2, taking the carbon fiber mesh cloth as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth, wherein the lamination pressure is not lower than 15MPa, and the lamination time is not lower than 30min;
s3, under the condition that the pressing pressure is kept after hot melting pressing, heat treatment is carried out after the temperature is increased, the carbon fiber mesh cloth is arranged in the middle of the mold, and the upper side and the lower side of the carbon fiber mesh cloth are respectively provided with mixed resin; the height of the supporting layer is 0.1-0.15mm, and the thickness of the first filtering layer and the second filtering layer is 0.04-0.06mm.
When processing, a mould is adopted for processing, the mould comprises an annular shell, a fixed channel for fixing carbon fiber mesh cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper tempered glass is arranged on the surface of the upper pressure plate, lower tempered glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper tempered glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower tempered glass; the number of the upper microwave generators and the lower microwave generators is 9, the size of the upper pressing plate and the lower pressing plate is 500mm by 500mm, and the maximum heating power of the upper microwave generators and the lower microwave generators is 500W. Heating by using an upper microwave generator and a lower microwave generator in a hot melting and pressing way, wherein the heating temperature is 300-350 ℃; the heat treatment temperature is 420-440 deg.C, and the time is 4-5min;
s4, reprocessing:
reducing the pressure to 0.5-1MPa, and then intermittently heating by using an upper microwave generator and a lower microwave generator, wherein the heating power is not lower than 300W, the heating time and the heating interval are controlled so that the temperature is not higher than 200 ℃ and the time is 60-90s.
For the filter screen, the synthesis is as follows:
example 1:
s1, mixing 6kg of polytetrafluoroethylene resin, 1kg of polyacrylonitrile resin and 0.5kg of polystyrene resin to obtain mixed resin;
s2, taking carbon fiber mesh cloth with the thickness of 0.1mm and the space size of 10mm + 10mm as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth at the lamination pressure of 15MPa for 30min;
s3, under the condition that the pressing pressure is kept after hot melting pressing, the temperature is increased, then heat treatment is carried out, the carbon fiber mesh cloth is arranged in the middle of the mold, and the upper side and the lower side of the carbon fiber mesh cloth are respectively provided with mixed resin; the height of the support layer is 0.1mm, and the thickness of the first filter layer and the second filter layer is 0.04mm.
When processing, a mould is adopted for processing, the mould comprises an annular shell, a fixed channel for fixing carbon fiber mesh cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper tempered glass is arranged on the surface of the upper pressure plate, lower tempered glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper tempered glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower tempered glass; the number of the upper microwave generators and the lower microwave generators is 9, the size of the upper pressing plate and the lower pressing plate is 500mm by 500mm, and the heating power of the upper microwave generators and the lower microwave generators is up to 500W. Heating by using an upper microwave generator and a lower microwave generator in a hot melting and pressing way, wherein the heating temperature is up to 300 ℃; the heat treatment temperature is 420 deg.C, and the time is 5min;
s4, reprocessing:
reducing the pressure to 0.5MPa, and then intermittently heating the mixture by using an upper microwave generator and a lower microwave generator, wherein the heating power is not lower than 300W, the heating time and the heating interval are controlled so that the control temperature is not higher than 200 ℃ and the total time is controlled to be 90s.
The tests were carried out according to the method described in standard GB/T32361-2015, in μm: soaking a sample to be detected by using low surface tension liquid to ensure that all pores are filled with wetting liquid; the sample was mounted on a jig, vented, and the gas pressure was increased stepwise. As the gas pressure increases, the surface tension of the liquid is overcome until the liquid is drained from the pores, and the relationship between the gas pressure and the gas flow rate during this process is recorded, referred to as the "wet" curve; when all the liquid is discharged, recording the relation between the gas pressure and the gas flow, and calling the relation as a dry curve; the average pore size was 5.9 μm as calculated from the "dry" and "wet" curves.
The tensile strength was measured according to GB/T1040.3-2006 to be 7.3MPa.
Example 2:
s1, mixing 8kg of polytetrafluoroethylene resin, 2kg of polyacrylonitrile resin and 1kg of polystyrene resin to obtain mixed resin;
s2, taking carbon fiber mesh cloth with the thickness of 0.15mm and the space size of 10mm + 10mm as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth under the lamination pressure of 15MPa for 30min;
s3, under the condition that the pressing pressure is kept after hot melting pressing, the temperature is increased, then heat treatment is carried out, the carbon fiber mesh cloth is arranged in the middle of the mold, and the upper side and the lower side of the carbon fiber mesh cloth are respectively provided with mixed resin; the height of the support layer is 0.15mm, and the thickness of the first filter layer and the second filter layer is 0.06mm.
When processing, a mould is adopted for processing, the mould comprises an annular shell, a fixed channel for fixing carbon fiber mesh cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper tempered glass is arranged on the surface of the upper pressure plate, lower tempered glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper tempered glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower tempered glass; the number of the upper microwave generators and the lower microwave generators is 9, the size of the upper pressing plate and the lower pressing plate is 500mm by 500mm, and the maximum heating power of the upper microwave generators and the lower microwave generators is 500W. Heating by using an upper microwave generator and a lower microwave generator in a hot melting and pressing manner, wherein the heating temperature is 350 ℃; the temperature of the heat treatment is 440 ℃, and the time is 4min;
s4, reprocessing:
reducing the pressure to 1MPa, and then intermittently heating the mixture by using an upper microwave generator and a lower microwave generator, wherein the heating power is not lower than 300W, the heating time and the heating interval are controlled so that the control temperature is not higher than 200 ℃ and the total time is controlled to be 60s.
The tests were carried out according to the method described in standard GB/T32361-2015, in μm: soaking a sample to be detected by using low surface tension liquid to ensure that all pores are filled with wetting liquid; the sample was mounted on a jig, vented, and the gas pressure was increased stepwise. As the gas pressure increases, the surface tension of the liquid is overcome until the liquid is drained from the pores, and the relationship between the gas pressure and the gas flow rate during this process is recorded, referred to as the "wet" curve; after all the liquid is discharged, recording the relation between the gas pressure and the gas flow, and calling a dry curve; the average pore size was 6.4 μm as calculated from the "dry" and "wet" curves.
The tensile strength was determined to be 7.1MPa according to GB/T1040.3-2006.
Comparative example 1:
s1, mixing 8kg of polytetrafluoroethylene resin, 2kg of polyacrylonitrile resin and 1kg of polystyrene resin to obtain mixed resin;
s2, taking carbon fiber mesh cloth with the thickness of 0.15mm and the space size of 10mm + 10mm as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth under the lamination pressure of 15MPa for 30min;
s3, under the condition that the pressing pressure is kept after hot melting pressing, the temperature is increased, then heat treatment is carried out, the carbon fiber mesh cloth is arranged in the middle of the mold, and the upper side and the lower side of the carbon fiber mesh cloth are respectively provided with mixed resin; the height of the support layer is 0.15mm, and the thickness of the first filter layer and the second filter layer is 0.06mm.
When the processing is carried out, a mould is adopted for processing, the mould comprises an annular shell, a fixed channel for fixing carbon fiber gridding cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper toughened glass is arranged on the surface of the upper pressure plate, lower toughened glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper toughened glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower toughened glass; the number of the upper microwave generators and the lower microwave generators is 9, the size of the upper pressing plate and the lower pressing plate is 500mm by 500mm, and the maximum heating power of the upper microwave generators and the lower microwave generators is 500W. Heating by using an upper microwave generator and a lower microwave generator in a hot melting and pressing manner, wherein the heating temperature is 350 ℃; the heat treatment temperature is 440 deg.C, and the time is 4min;
the tests were carried out according to the method described in standard GB/T32361-2015, in μm: soaking a sample to be detected by using low surface tension liquid to ensure that all pores are filled with wetting liquid; the sample was mounted on a jig, vented, and the gas pressure was increased stepwise. As the gas pressure increases, the surface tension of the liquid is overcome until the liquid is drained from the pores, and the relationship between the gas pressure and the gas flow rate during this process is recorded, referred to as the "wet" curve; after all the liquid is discharged, recording the relation between the gas pressure and the gas flow, and calling a dry curve; the average pore size was 2.4 μm as calculated from the "dry" and "wet" curves.
The tensile strength was measured according to GB/T1040.3-2006 to be 8.7MPa.
The above are merely examples of the present application and are not intended to limit the present application. Various modifications and changes may occur to those skilled in the art to which the present application pertains. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of the claims of the present application.
Claims (10)
1. A medicine stock solution filter equipment who contains fine particle which characterized in that: comprises a cavity to be filtered, and a purifying cavity is arranged below the cavity to be filtered; a separation plate is arranged between the cavity to be filtered and the purification cavity, a plurality of communication holes are formed in the separation plate, a filtering cylinder is inserted in the communication holes, and the filtering cylinder is arranged in the cavity to be filtered; the filtering cylinder comprises a supporting shell, and a filtering net is arranged on the outer side of the supporting shell; the support shell is provided with an annular fixed plate on one side of the purification cavity, and the end part of the filter screen is fixedly arranged between the annular fixed plate and the isolation plate.
2. The apparatus for filtering a drug solution containing fine particles as set forth in claim 1, wherein: an upper lead-in pipeline is arranged at the upper part of the filtering shell, and a side lead-out pipeline is arranged at the bottom of the isolation plate; a lower guide pipeline is arranged at the bottom of the purifying cavity.
3. The apparatus for filtering a drug solution containing fine particles as set forth in claim 1, wherein: the filter screen includes first filter layer, supporting layer, the second filter layer that sets gradually from the top down.
4. The apparatus for filtering a drug solution containing fine particles as set forth in claim 3, wherein: the first filtering layer and the second filtering layer are polytetrafluoroethylene filtering membranes, and the supporting layer is a carbon fiber net layer.
5. The apparatus of claim 4, wherein the apparatus comprises: the filter screen is synthesized according to the following method:
mixing polytetrafluoroethylene resin, polyacrylonitrile resin and polystyrene resin to obtain mixed resin;
taking the carbon fiber mesh cloth as a carrier, and carrying out hot melting lamination on the mixed resin and the carbon fiber mesh cloth, wherein the lamination pressure is not lower than 15MPa, and the lamination time is not lower than 30min; in the case where the pressing pressure is maintained after the hot-melt pressing, the temperature is increased and then the heat treatment is performed.
6. The apparatus for filtering a drug solution containing fine particles as set forth in claim 5, wherein: the carbon fiber mesh cloth is arranged in the middle of the mold, and mixed resin is respectively arranged on the upper side and the lower side of the carbon fiber mesh cloth.
7. The apparatus for filtering a drug solution containing fine particles as set forth in claim 6, wherein: the height of the supporting layer is 0.1-0.15mm, and the thickness of the first filtering layer and the second filtering layer is 0.04-0.06mm.
8. The apparatus of claim 6, wherein the apparatus comprises: the mold comprises an annular shell, a fixed channel for fixing carbon fiber gridding cloth is arranged in the middle of the annular shell, an upper pressure plate is arranged at the upper part of the annular shell, a lower pressure plate is arranged at the lower part of the annular shell, upper toughened glass is arranged on the surface of the upper pressure plate, lower toughened glass is arranged on the surface of the lower pressure plate, a plurality of upper microwave generators are uniformly distributed on the inner side of the upper pressure plate relative to the upper toughened glass, and a plurality of lower microwave generators are uniformly distributed on the inner side of the lower pressure plate relative to the lower toughened glass; the number of the upper microwave generators and the lower microwave generators is 9.
9. The apparatus of claim 8, wherein the filter is a filter for a drug solution containing fine particles, the apparatus comprising: heating by using an upper microwave generator and a lower microwave generator in a hot melting and pressing way, wherein the heating temperature is 300-350 ℃; the heat treatment temperature is 420-440 deg.C, and the time is 4-5min.
10. The apparatus for filtering a drug solution containing fine particles as set forth in claim 8, wherein: after the pressing, the method also comprises a reprocessing process after the heat treatment, wherein the pressure is reduced to 0.5-1MPa, then an upper microwave generator and a lower microwave generator are used for carrying out intermittent heating, the heating power is not lower than 300W, the heating time and the heating interval are controlled so that the temperature is not higher than 200 ℃ and the time is 60-90s.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210988386.6A CN115337694A (en) | 2022-08-17 | 2022-08-17 | Medicine stock solution filter equipment who contains fine particle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210988386.6A CN115337694A (en) | 2022-08-17 | 2022-08-17 | Medicine stock solution filter equipment who contains fine particle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115337694A true CN115337694A (en) | 2022-11-15 |
Family
ID=83952896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210988386.6A Pending CN115337694A (en) | 2022-08-17 | 2022-08-17 | Medicine stock solution filter equipment who contains fine particle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115337694A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312758A (en) * | 1998-08-18 | 2001-09-12 | 大金工业株式会社 | Polytetrafluoroethylene laminate |
| CN101161328A (en) * | 2006-10-12 | 2008-04-16 | 姚宇 | Slagoff type stereo filter |
| CN102274650A (en) * | 2011-07-26 | 2011-12-14 | 合肥三番水处理设备有限公司 | Highly-integrated hollow fiber column filter |
| CN102516037A (en) * | 2011-11-25 | 2012-06-27 | 锡矿山闪星锑业有限责任公司 | Method for preparing ethylene glycol antimony ester by rapid impurity removal and decoloration |
| CN205549840U (en) * | 2016-04-06 | 2016-09-07 | 天津清科环保科技有限公司 | High accuracy, high temperature resistant filter material of high strength |
| CN106693517A (en) * | 2016-08-12 | 2017-05-24 | 浙江大学昆山创新中心 | Preparation method of flame-resistant membrane-laminating filtering material capable of being cured at room temperature and repeatedly utilized |
| CN207401264U (en) * | 2017-08-31 | 2018-05-25 | 浙江华基环保科技有限公司 | A kind of novel dust removing filter felt |
| CN108499261A (en) * | 2018-04-20 | 2018-09-07 | 江苏绿地环保滤材有限公司 | A kind of Environmental-protection dust removal device going peculiar smell antibacterial |
| CN109641413A (en) * | 2016-08-24 | 2019-04-16 | 沙特基础工业全球技术有限公司 | Device and method for manufacturing composite construction |
-
2022
- 2022-08-17 CN CN202210988386.6A patent/CN115337694A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312758A (en) * | 1998-08-18 | 2001-09-12 | 大金工业株式会社 | Polytetrafluoroethylene laminate |
| CN101161328A (en) * | 2006-10-12 | 2008-04-16 | 姚宇 | Slagoff type stereo filter |
| CN102274650A (en) * | 2011-07-26 | 2011-12-14 | 合肥三番水处理设备有限公司 | Highly-integrated hollow fiber column filter |
| CN102516037A (en) * | 2011-11-25 | 2012-06-27 | 锡矿山闪星锑业有限责任公司 | Method for preparing ethylene glycol antimony ester by rapid impurity removal and decoloration |
| CN205549840U (en) * | 2016-04-06 | 2016-09-07 | 天津清科环保科技有限公司 | High accuracy, high temperature resistant filter material of high strength |
| CN106693517A (en) * | 2016-08-12 | 2017-05-24 | 浙江大学昆山创新中心 | Preparation method of flame-resistant membrane-laminating filtering material capable of being cured at room temperature and repeatedly utilized |
| CN109641413A (en) * | 2016-08-24 | 2019-04-16 | 沙特基础工业全球技术有限公司 | Device and method for manufacturing composite construction |
| CN207401264U (en) * | 2017-08-31 | 2018-05-25 | 浙江华基环保科技有限公司 | A kind of novel dust removing filter felt |
| CN108499261A (en) * | 2018-04-20 | 2018-09-07 | 江苏绿地环保滤材有限公司 | A kind of Environmental-protection dust removal device going peculiar smell antibacterial |
Non-Patent Citations (1)
| Title |
|---|
| 中国材料研究学会 等: "中国战略性新兴产业 新材料 环境工程材料", 中国铁道出版社, pages: 47 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102847368B (en) | Method for separating catalyst by using ceramic membrane filter, and apparatus thereof | |
| CN115337694A (en) | Medicine stock solution filter equipment who contains fine particle | |
| CN107983303A (en) | A kind of preparation method of organic wastewater absorption degradation modified carbon fiber | |
| CN102806019B (en) | Multifunctional composite filtering diaphragm plate | |
| CN104402687B (en) | A kind of production technique of phenol hydrogenation preparing cyclohexanone | |
| CN104561592A (en) | Nickel-containing electroplating wastewater treatment and nickel recovery method | |
| CN202164222U (en) | Mud cake discharging device used for sludge dewatering machine | |
| CN110563796B (en) | Highland barley protein separation and purification method | |
| CN115253426A (en) | Waste water treatment device | |
| CN112340811A (en) | Silicon carbide ceramic membrane clarification equipment | |
| CN202751957U (en) | Multifunctional composite filter membrane plate | |
| CN108927203B (en) | Regeneration method of phenol hydrogenation Pd @ CN catalyst | |
| CN217323380U (en) | System for utilize nitrogen trifluoride byproduct to retrieve high-purity hydrogen energy | |
| CN214486398U (en) | A hydrolysate nanofiltration device for producing glucosamine hydrochloride | |
| CN210728784U (en) | Precision concentration plate type filter plate and filter using same | |
| CN108854581B (en) | Preparation method of high-strength composite tubular membrane | |
| CN201195700Y (en) | Dynamic state film supporting body for implementing water supply/wastewater treatment | |
| CN211677660U (en) | Novel hydrogen peroxide wedge-shaped cone grid support | |
| CN215196335U (en) | Nanofiltration membrane concentration equipment | |
| CN209451396U (en) | A kind of filter device and reciprocating apparatus for screening fibrous suspensions | |
| CN205699632U (en) | A kind of solvent recovery fine filtering device produced for carbon fiber | |
| CN106478434A (en) | A kind of method of production 2 methylamino, 5 chlorobenzophenone | |
| CN210410237U (en) | Seal separator for milipore filter | |
| CN209188271U (en) | A kind of cartridge filter high efficiency filter filter core | |
| CN214115001U (en) | Filter element for reverse osmosis device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |