CN115335873A - 一种诊断方法 - Google Patents

一种诊断方法 Download PDF

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Publication number
CN115335873A
CN115335873A CN202180022866.0A CN202180022866A CN115335873A CN 115335873 A CN115335873 A CN 115335873A CN 202180022866 A CN202180022866 A CN 202180022866A CN 115335873 A CN115335873 A CN 115335873A
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CN
China
Prior art keywords
image
cells
disease
subject
microglia
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Pending
Application number
CN202180022866.0A
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English (en)
Chinese (zh)
Inventor
M·F·科代罗
J·麦迪逊
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UCL Business Ltd
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UCL Business Ltd
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Publication date
Application filed by UCL Business Ltd filed Critical UCL Business Ltd
Publication of CN115335873A publication Critical patent/CN115335873A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/24—Classification techniques
    • G06F18/241—Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches
    • G06F18/2413—Classification techniques relating to the classification model, e.g. parametric or non-parametric approaches based on distances to training or reference patterns
    • G06F18/24133—Distances to prototypes
    • G06F18/24137—Distances to cluster centroïds
    • G06F18/2414—Smoothing the distance, e.g. radial basis function networks [RBFN]
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/82—Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H30/00—ICT specially adapted for the handling or processing of medical images
    • G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V2201/00—Indexing scheme relating to image or video recognition or understanding
    • G06V2201/03—Recognition of patterns in medical or anatomical images

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • General Physics & Mathematics (AREA)
  • Evolutionary Computation (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Multimedia (AREA)
  • Public Health (AREA)
  • Databases & Information Systems (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Computing Systems (AREA)
  • Molecular Biology (AREA)
  • Software Systems (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Eye Examination Apparatus (AREA)
  • Control Of Eletrric Generators (AREA)
CN202180022866.0A 2020-01-22 2021-01-22 一种诊断方法 Pending CN115335873A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2000926.2A GB202000926D0 (en) 2020-01-22 2020-01-22 Method of diagnosis
GB2000926.2 2020-01-22
PCT/EP2021/051527 WO2021148653A1 (en) 2020-01-22 2021-01-22 Method of diagnosis

Publications (1)

Publication Number Publication Date
CN115335873A true CN115335873A (zh) 2022-11-11

Family

ID=69636892

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180022866.0A Pending CN115335873A (zh) 2020-01-22 2021-01-22 一种诊断方法

Country Status (8)

Country Link
US (2) US20230047141A1 (https=)
EP (1) EP4094183A1 (https=)
JP (2) JP2023514063A (https=)
CN (1) CN115335873A (https=)
AU (1) AU2021211150A1 (https=)
CA (1) CA3165693A1 (https=)
GB (1) GB202000926D0 (https=)
WO (1) WO2021148653A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI784688B (zh) * 2021-08-26 2022-11-21 宏碁股份有限公司 眼睛狀態評估方法及電子裝置
US20240420490A1 (en) * 2021-10-19 2024-12-19 Denali Therapeutics Inc. Microglial cell morphometry
JP2024118806A (ja) * 2023-02-21 2024-09-02 株式会社Ｓｃｒｅｅｎホールディングス 画像表示方法、画像表示装置およびプログラム
WO2024177720A1 (en) * 2023-02-26 2024-08-29 The Schepens Eye Research Institute, Inc. Secreted phosphoprotein 1 (spp1) as a neuroprotective therapy in neurodegenerative disease
KR20240178906A (ko) * 2023-06-23 2024-12-31 현대제철 주식회사 소재 분석 방법

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771645B2 (en) * 2007-12-14 2014-07-08 UCL Business PLLC Composition comprising a cell death marker and a wavelength-optimized label

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060134001A1 (en) 2002-07-12 2006-06-22 Frangioni John V Conjugated infrared fluorescent substances for detection of cell death
JP5701485B2 (ja) * 2006-02-21 2015-04-15 テバ ファーマシューティカル インダストリーズ リミティド 多系統萎縮症の治療のためのラサギリンの使用
EP2044951A1 (en) * 2007-10-02 2009-04-08 Merz Pharma GmbH & Co. KGaA The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
GB0724606D0 (en) 2007-12-18 2008-01-30 Xennia Technology Ltd Recirculating ink system for industrial inkjet printing
GB0919520D0 (en) 2009-11-06 2009-12-23 Ucl Business Plc Quantifying cell death
US20160270647A1 (en) * 2013-10-25 2016-09-22 The General Hospital Corporation System, method and computer-accessible medium for determining inflammation associated with a central nervous system
AU2017312499B2 (en) * 2016-08-19 2023-02-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Selective estrogen-receptor modulators (SERMs) confer protection against photoreceptor degeneration
EP3525659A4 (en) * 2016-10-13 2020-06-17 Translatum Medicus, Inc. SYSTEMS AND METHODS FOR DETECTING EYE DISEASES

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8771645B2 (en) * 2007-12-14 2014-07-08 UCL Business PLLC Composition comprising a cell death marker and a wavelength-optimized label

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANA I. RAMIREZ ET AL.: "The Role of Microglia in Retinal Neurodegeneration: Alzheimer’s Disease, Parkinson, and Glaucoma", FRONTIERS IN AGING NEUROSCIENCE, vol. 9, 6 July 2017 (2017-07-06), pages 1 - 21 *
DAVID REICHSTEIN ET AL.: "Apoptotic retinal ganglion cell death in the DBA/2 mouse model of glaucoma", EXPERIMENTAL EYE RESEARCH, vol. 84, 30 October 2006 (2006-10-30), pages 13 - 21, XP005727361, DOI: 10.1016/j.exer.2006.08.009 *
MUKHTAR BIZRAH ET AL.: "A semi-automated technique for labeling and counting of apoptosing retinal cells", BMC BIOINFORMATICS, vol. 15, 5 June 2014 (2014-06-05), pages 1 - 12 *

Also Published As

Publication number Publication date
EP4094183A1 (en) 2022-11-30
AU2021211150A1 (en) 2022-09-08
WO2021148653A1 (en) 2021-07-29
US20260017957A1 (en) 2026-01-15
CA3165693A1 (en) 2021-07-29
JP2026021537A (ja) 2026-02-10
GB202000926D0 (en) 2020-03-04
US20230047141A1 (en) 2023-02-16
JP2023514063A (ja) 2023-04-05

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