CN115307997A

CN115307997A - Clinical laboratory's sample preparation facilities

Info

Publication number: CN115307997A
Application number: CN202210956267.2A
Authority: CN
Inventors: 陈凤花; 李归宁; 王秀娟
Original assignee: Tongji Medical College of Huazhong University of Science and Technology
Current assignee: Tongji Medical College of Huazhong University of Science and Technology
Priority date: 2022-08-10
Filing date: 2022-08-10
Publication date: 2022-11-08

Abstract

The invention belongs to the technical field of clinical laboratory, in particular to a clinical laboratory sample preparation device, which aims at the problems that the number of samples required to be prepared simultaneously is large, the slices after corpses are frozen can be prepared only after thawing and air-drying operations are carried out one by one, and the whole consumed time is long. The normal saline is added into the treatment box, the frozen section is assisted to be thawed by adopting a water bath thawing mode, the whole time for preparing the section specimen is shortened, meanwhile, the thawing process is assisted by the spiral heating pipe and the air disc, the thawing time for freezing the specimen is further shortened, the long time for preparing the specimen after freezing the corpse section is avoided, and the whole specimen preparation effect is improved.

Description

Clinical laboratory's sample preparation facilities

Technical Field

The invention relates to the technical field of clinical laboratory, in particular to a preparation device for a clinical laboratory specimen.

Background

Clinical laboratory is the bridge between clinical medicine and basic medicine, and includes clinical chemistry, clinical microbiology, clinical immunology, hematology, humoral and transfusion science branch subjects, undertakes daily detection work including ward, outpatient and emergency patients, various physical examinations and scientific research on various human specimens.

The specimen is an animal, plant, mineral, etc., and can be preserved for a long time and maintain the original appearance as much as possible after various treatments, thereby providing the specimen for exhibition, demonstration, education, identification, examination and other various researches.

The clinical laboratory needs to frequently prepare human body specimens to provide subsequent research work, and because the number of specimens needing to be prepared is large, the frozen sections of the corpses can be prepared only after being frozen one by one and subjected to air drying, and the whole time consumption is long.

Disclosure of Invention

The invention provides a clinical laboratory sample preparation device which comprises a bottom plate, wherein an air drying box is arranged above the bottom plate, an air blowing assembly and an exhaust assembly are arranged inside the air drying box, a side seat is arranged on one side of the air drying box, the side seat is fixedly connected with the bottom plate, a treatment box is fixedly connected inside the side seat, a spiral heating pipe is arranged inside the treatment box, two symmetrical circular grooves are formed in the bottom of the treatment box, air discs are fixedly connected inside the two circular grooves, a plurality of exhaust holes are formed in the air discs, an air blower is fixedly connected to one side of the air drying box, an output port of the air blower is fixedly connected with a bottom attached air delivery pipe, and the other end of the bottom attached air delivery pipe is connected with the two air discs through a pipeline.

Preferably, the blowing assembly comprises a heating cylinder, an air conveying cylinder and a blowing box, the heating cylinder is connected with the air conveying cylinder through a pipeline, a rectangular concave hole is formed in one side of the air drying box, the blowing box is fixedly connected with the inner wall of the rectangular concave hole, and the air conveying cylinder is communicated with the blowing box.

Preferably, another output port of the air blower is fixedly connected with a main air pipe, the other end of the main air pipe is fixedly connected with the lower end of the heating cylinder, the heating cylinder is fixedly connected with the outer side of the air drying box, and a plurality of equidistant heating wires are arranged in the heating cylinder.

Preferably, the exhaust subassembly is including straining a section of thick bamboo and the case of airing exhaust, and the rectangle shrinkage pool has been seted up to one side of air-drying box, and the inner wall fixed connection of air-discharging box and rectangle shrinkage pool, air-discharging box and strain through the pipe connection between the section of thick bamboo, strain the outside fixed connection of a section of thick bamboo and air-drying box, the inside of straining a section of thick bamboo is provided with a plurality of equidistant active carbon filter layers, and strains the last gas outlet fixedly connected with pipeline of a section of thick bamboo, the other end fixedly connected with air discharge fan of pipeline, the outside fixed connection of air discharge fan and air-drying box.

Preferably, all seted up the rectangle draw-in groove on air-drying box and the processing case, the inside joint of rectangle draw-in groove has the frame of moving, moves and puts equal fixedly connected with vaulting pole on the frame, and is provided with the thing subassembly of putting of a plurality of equidistance on the vaulting pole.

Preferably, put the thing subassembly and include supporter and overhead dish, set up the round hole of two symmetries on the supporter, the inside fixed connection of vaulting pole and round hole, and fixedly connected with montant on the supporter, the overhead dish is located the montant directly over, and hexagonal recess has all been seted up to the upper end of montant and the downside of overhead dish.

Preferably, the outer side of the overhead plate is fixedly connected with three struts which are circumferentially equidistant, the top ends of the three struts are fixedly connected with a pressure plate, and the upper side of the overhead plate is fixedly connected with a connecting plate.

Preferably, the other end fixedly connected with inserted bar of connecting plate, the bottom fixedly connected with disc boss of inserted bar, and the upside fixedly connected with of supporter stands a section of thick bamboo, and the column recess has been seted up to the inside of a section of thick bamboo of standing, the inside swing joint of the column recess of disc boss and the section of thick bamboo of standing on the inserted bar, the downside fixedly connected with reset spring of disc boss, reset spring's the other end and the inside fixed connection of the column recess of a section of thick bamboo of standing.

Preferably, it is a plurality of it places the subassembly to be provided with the sample between the thing subassembly to put, and the sample place the subassembly and include connection pad and three sample dish, has seted up the round hole on the connection pad, the inner wall fixedly connected with gag lever post of round hole, the equal fixedly connected with hexagonal lug in upper and lower both ends of gag lever post, two upper and lower hexagonal lugs respectively with montant and overhead dish on hexagonal recess swing joint.

Preferably, it is three fixed connection between specimen tray and the connection pad, three specimen tray are circumference equidistance and distribute, have all seted up the small opening on the three specimen tray, and the inside of three specimen tray all is provided with a plurality of unsettled archs, and the top of three specimen tray all is provided with the net pad, net pad and unsettled bellied upside fixed connection.

The beneficial effects of the invention are as follows:

1. according to the invention, through the arrangement of the bottom plate, the air drying box, the side seat, the processing box, the spiral heating pipe, the air disc, the air blower and the bottom attached air delivery pipe, the normal saline is added into the processing box, the frozen section is assisted to be thawed by adopting a water bath thawing mode, the whole time for preparing the section sample is shortened, meanwhile, the spiral heating pipe and the air disc are used for assisting the thawing process, the thawing time of the frozen sample is further shortened, the long time for preparing the sample after the frozen corpse is sliced is avoided, and the whole sample preparation effect is improved.

2. According to the invention, through the arranged blowing assembly, the blowing assembly can be used for heating gas and then conveying the heated gas into the air drying box for air drying operation, the time required by dicing and air drying is shortened, the preparation efficiency of the specimen is improved, the electric heating wires are distributed in the cylindrical heating cylinder and can be contacted with the gas circulating in the heating cylinder as much as possible, so that the temperature of the heating cylinder is improved, the temperature of the circulating gas can be controlled through the arrangement of the gas conveying cylinder, and the problem that the sliced specimen preparation is influenced due to overhigh gas temperature caused by excessive heating of the heating cylinder is avoided.

3. According to the invention, through the arranged exhaust assembly, the air inside the air drying box can be promoted to circulate by using the exhaust assembly, and meanwhile, the air after air drying operation is filtered, so that the influence of peculiar smell in the air on the working environment is avoided.

4. According to the invention, through the moving frame, the support rods and the object placing assemblies, the object placing assemblies can be used for fixing and limiting the sample placing assemblies in which the cut specimens are placed, so that a plurality of groups of sample placing assemblies can be arranged on the support rods in a layered manner, the subsequent centralized defrosting and air drying operation is facilitated, and the preparation requirements of a plurality of specimens are further met; utilize reset spring's elastic property can be convenient for carry out the sample and place the spacing of subassembly fixed, and it is spacing that the pressure disk covers in the stripping and slicing upside and pushes down it, avoids it to freeze in the follow-up melting, waterlogging caused by excessive rainfall and air-drying process emergence skew, causes the sample to break away from in the sample dish.

5. According to the invention, through the arranged sample placing assembly, three cut-block samples can be placed at the same time by utilizing the sample placing assembly, the preparation requirements of a plurality of samples are met, the leakage groove on the sample tray can facilitate the outflow of liquid, the suspended bulge can suspend the placed cut-block, and the contact effect with the bottom of the cut-block is reduced, so that the flowing of the liquid and the circulation of air flow during the subsequent air drying operation are accelerated, the draining and air drying effects are improved, the whole preparation time is shortened, the grid pad is easy to replace, the cleanness of the sample tray is ensured when different samples are prepared, and the influence of dirt on the preparation of the samples is avoided.

Drawings

FIG. 1 is a schematic view of the overall structure of a specimen preparation apparatus for clinical laboratory according to the present invention;

FIG. 2 is a schematic view of a processing chamber of a specimen preparation apparatus for clinical laboratory according to the present invention;

FIG. 3 is a schematic view of the internal structure of an air drying box of the specimen preparation device of the clinical laboratory according to the present invention;

FIG. 4 is a schematic structural view of a blower assembly of the clinical laboratory specimen preparation apparatus according to the present invention;

FIG. 5 is a schematic view of a partial structure of a specimen preparation apparatus for clinical laboratory according to the present invention;

FIG. 6 is a schematic diagram of a rack of the specimen preparation device of the clinical laboratory according to the present invention;

FIG. 7 is a schematic view of a placement module of a clinical laboratory specimen preparation apparatus according to the present invention;

FIG. 8 is a schematic view of a specimen holding assembly of the clinical laboratory specimen preparation apparatus according to the present invention.

In the figure: 1. a base plate; 2. an air drying box; 3. a side seat; 4. a treatment tank; 5. a spiral heating pipe; 6. an air pan; 7. a blower; 8. a gas pipe is attached to the bottom; 9. a heating cylinder; 10. an air delivery cylinder; 11. a blow box; 12. a main gas delivery pipe; 13. an electric heating wire; 14. a filter cartridge; 15. an exhaust box; 16. an exhaust fan; 17. an activated carbon filter layer; 18. moving the frame; 19. a stay bar; 20. a rack; 21. a top-mounted disk; 22. a vertical rod; 23. a strut; 24. a platen; 25. a connecting plate; 26. inserting a rod; 27. a standing drum; 28. a return spring; 29. a connecting disc; 30. a limiting rod; 31. a specimen tray; 32. a leak groove; 33. hanging a bulge; 34. and (4) grid cushion.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.

The utility model provides a clinical laboratory's sample preparation facilities, as shown in figure 1 and figure 2, including bottom plate 1, the top of bottom plate 1 is provided with air-drying box 2, and air-drying box 2's inside is provided with blowing subassembly and exhaust subassembly, one side of air-drying box 2 is provided with side seat 3, through bolted connection between side seat 3 and the bottom plate 1, and there is treatment case 4 inside through bolted connection side seat 3, the inside of handling case 4 is provided with spiral heating pipe 5, and the bottom of handling case 4 has seted up the circular recess of two symmetries, there is air disc 6 inside of two circular recesses all through bolted connection, be provided with a plurality of exhaust holes on the air disc 6, there is air-blower 7 one side of air-drying box 2 through bolted connection, and an output port of air-blower 7 has attached gas-supply pipe 8 through bolted connection, pass through the pipe connection between the other end of attached gas-supply pipe 8 and two air discs 6 at the bottom.

Further, as shown in fig. 3 and 4, the blowing assembly includes a heating cylinder 9, an air conveying cylinder 10 and a blowing box 11, the heating cylinder 9 is connected with the air conveying cylinder 10 through a pipeline, a rectangular concave hole is formed in one side of the air drying box 2, the blowing box 11 is connected with the inner wall of the rectangular concave hole through a bolt, and the air conveying cylinder 10 is communicated with the blowing box 11; another output port of air-blower 7 has main gas-supply pipe 12 through bolted connection, the other end of main gas-supply pipe 12 passes through bolted connection with the lower extreme of cartridge heater 9, cartridge heater 9 passes through bolted connection with the outside of air-dry box 2, and the inside of cartridge heater 9 is provided with the heating wire 13 of a plurality of equidistance, heating wire 13 distributes in the cartridge heater 9 of tube-shape, can contact with the gas of circulation in the cartridge heater 9 as far as, thereby improve the temperature of cartridge heater 9, the gaseous temperature of circulation then can be controlled in the setting of cartridge heater 10, avoid cartridge heater 9 excessive heating to cause gaseous high temperature, influence sliced sample preparation.

Furthermore, as shown in fig. 3 and 4, the exhaust assembly includes a filter cartridge 14 and an exhaust box 15, a rectangular concave hole is formed in one side of the air drying box 2, the exhaust box 15 is connected with the inner wall of the rectangular concave hole through a bolt, the exhaust box 15 is connected with the filter cartridge 14 through a pipeline, the filter cartridge 14 is connected with the outer side of the air drying box 2 through a bolt, a plurality of equidistant activated carbon filter layers 17 are arranged inside the filter cartridge 14, the upper air outlet of the filter cartridge 14 is connected with the pipeline through a bolt, the other end of the pipeline is connected with an exhaust fan 16 through a bolt, the exhaust fan 16 is connected with the outer side of the air drying box 2 through a bolt, the exhaust assembly can promote the circulation of the gas inside the air drying box 2 and filter the gas after the air drying operation, so that the influence on the working environment caused by the peculiar smell doped in the gas is avoided.

Furthermore, as shown in fig. 5, 6 and 7, rectangular clamping grooves are respectively formed in the air drying box 2 and the processing box 4, a moving frame 18 is clamped inside the rectangular clamping grooves, the moving frame 18 is connected with a support rod 19 through bolts, and a plurality of equidistant placement components are arranged on the support rod 19; the article placing component comprises an article placing rack 20 and a top-mounted disk 21, wherein two symmetrical round holes are formed in the article placing rack 20, a support rod 19 is connected with the insides of the round holes through bolts, a vertical rod 22 is connected to the article placing rack 20 through a bolt, the top-mounted disk 21 is positioned right above the vertical rod 22, and hexagonal grooves are formed in the upper end of the vertical rod 22 and the lower side of the top-mounted disk 21; the outer side of the overhead plate 21 is connected with three support rods 23 with equal intervals in the circumference through bolts, the top ends of the three support rods 23 are connected with a pressure plate 24 through bolts, and the upper side of the overhead plate 21 is connected with a connecting plate 25 through bolts; the other end of connecting plate 25 has inserted bar 26 through bolted connection, there is the disc boss bottom of inserted bar 26 through bolted connection, and there is a section of thick bamboo 27 of standing through bolted connection on the upside of supporter 20, the column recess has been seted up to the inside of a section of thick bamboo 27 of standing, disc boss and the inside sliding connection of the column recess of a section of thick bamboo 27 of standing on the inserted bar 26, there is reset spring 28 disc boss's downside through bolted connection, reset spring 28's the other end and the inside bolted connection that passes through of the column recess of a section of thick bamboo 27 of standing, it is fixed to utilize reset spring 28's elastic property can be convenient for carry out the spacing of sample placement component, it is spacing to push down in the stripping upside to it is covered to pressure disk 24, avoid it to freeze in follow-up changes, the skew takes place for waterlogging caused the sample to break away from in sample dish 31.

Furthermore, as shown in fig. 6 and 8, a specimen placing assembly is arranged between the plurality of article placing assemblies, and the specimen placing assembly includes a connecting disc 29 and three specimen trays 31, a circular hole is formed on the connecting disc 29, the inner wall of the circular hole is connected with a limiting rod 30 through a bolt, the upper end and the lower end of the limiting rod 30 are both connected with hexagonal lugs through bolts, and the upper hexagonal lug and the lower hexagonal lug are respectively inserted into the hexagonal grooves on the vertical rod 22 and the top tray 21; pass through bolted connection between three specimen dish 31 and the connection pad 29, three specimen dish 31 is the circumference equidistance and distributes, the small opening 32 has all been seted up on three specimen dish 31, the inside of three specimen dish 31 all is provided with a plurality of unsettled archs 33, and the top of three specimen dish 31 all is provided with net pad 34, net pad 34 bonds with unsettled protruding 33's upside, the small opening 32 can be convenient for the outflow of liquid on the specimen dish 31, unsettled protruding 33 can be unsettled with the stripping and slicing that places, reduce the contact effect with the stripping and slicing bottom, thereby the circulation of air current when accelerating the flow of liquid and follow-up air-dry operation, improve waterlogging caused by excessive rainfall and air-drying effect, shorten holistic preparation time, net pad 34 is easily changed, guarantee the cleanness of specimen dish 31 when being convenient for different specimen preparation, avoid depositing dirty preparation that influences the preparation of sample.

The working principle is as follows: after the frozen corpse blocks of the specimen to be prepared are cut, the frozen corpse blocks are placed in specimen trays 31, after three specimen trays 31 on one specimen placing assembly are placed, the frozen corpse blocks are fixed on one article placing assembly (the connecting plate 25 is lifted upwards to enable the inserted rod 26 to slide upwards in the standing barrel 27, the distance between the top tray 21 and the vertical rod 22 is increased, then the specimen placing assembly is placed between the top tray 21 and the vertical rod 22, the pulling force of the connecting plate 25 is removed, the reset spring 28 recovers elasticity and provides reverse acting force, the upper hexagonal bump and the lower hexagonal bump of the limiting rod 30 are inserted into the hexagonal grooves on the top tray 21 and the vertical rod 22, the pressure tray 24 covers the upper side of the cut blocks, after the specimen placing assemblies are installed on the supporting rod 19, the specimen placing assemblies are firstly placed in the processing box 4 for defrosting and draining, and then placed in the air drying box 2 for air drying operation;

the defrosting and draining treatment process comprises the following steps: after a support rod 19 and a moving frame 18 which are provided with a specimen placing component are placed in a processing box 4, normal saline is added into the processing box 4 until all the cut specimens are submerged, then a box door is closed, a spiral heating pipe 5 is electrified for heating, a blower 7 conveys gas to an air disc 6 through a bottom attached gas conveying pipe 8, the temperature of the normal saline in the box is increased, the thawing of frozen sections is accelerated, meanwhile, the air disc 6 conveys bubbles upwards, the contact effect between liquid and the sections is improved, the thawing is further assisted, and the support rod 19 and the moving frame 18 are lifted upwards after thawing and are left unused for draining;

and (3) air-drying operation process: the vaulting pole 19 after waterlogging caused by excessive rainfall and move frame 18 and put into air-dry box 2 along with the sample of thawing, close the chamber door, air blower 7 carries gas in the cartridge heater 9 through main gas-supply pipe 12, heating wire 13 heats the gas of carrying, blow out from the case of blowing 11 through gas-supply pipe 10 afterwards, carry out the drying of blowing to the fritter in the air-dry box 2, outside air discharge fan 16 circular telegram work simultaneously, carry the gas in the air-dry box 2 to the outside, the gas of air-dry operation can lead to cartridge filter 14 during this period, active carbon filter layer 17 filters the convection current ventilation body, avoid doping the strange smell in the gas.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims

1. The utility model provides a clinical laboratory's sample preparation facilities, includes bottom plate (1), its characterized in that, the top of bottom plate (1) is provided with air-drying box (2), and the inside of air-drying box (2) is provided with subassembly and the exhaust subassembly of blowing, one side of air-drying box (2) is provided with side seat (3), fixed connection between side seat (3) and bottom plate (1), and the inside fixedly connected with of side seat (3) handles case (4), the inside of handling case (4) is provided with spiral heating pipe (5), and handles the bottom of case (4) and set up the circular recess of two symmetries, and the equal fixedly connected with air disc (6) in the inside of two circular recesses is provided with a plurality of exhaust holes on air disc (6), one side fixedly connected with of air-drying box (2) has bottom air-supply pipe (8), and an output port fixed connection of air-supply pipe (7) has bottom and attaches through the pipe connection between the other end of air-supply pipe (8) and two air discs (6).

2. The specimen preparation device of claim 1, wherein the blowing assembly comprises a heating cylinder (9), an air conveying cylinder (10) and a blowing box (11), the heating cylinder (9) is connected with the air conveying cylinder (10) through a pipeline, a rectangular concave hole is formed in one side of the air drying box (2), the blowing box (11) is fixedly connected with the inner wall of the rectangular concave hole, and the air conveying cylinder (10) is communicated with the blowing box (11).

3. The preparation device of clinical laboratory's sample according to claim 2, characterized in that, another output port of air-blower (7) fixedly connected with main gas-supply pipe (12), the other end of main gas-supply pipe (12) and the lower extreme fixed connection of heating cylinder (9), the outside fixed connection of heating cylinder (9) and air-dry box (2), and the inside of heating cylinder (9) is provided with a plurality of equidistant heating wires (13).

4. The clinical laboratory specimen preparation device according to claim 1, wherein the exhaust assembly comprises a filter cartridge (14) and an exhaust box (15), a rectangular concave hole is formed in one side of the air drying box (2), the exhaust box (15) is fixedly connected with the inner wall of the rectangular concave hole, the exhaust box (15) is connected with the filter cartridge (14) through a pipeline, the filter cartridge (14) is fixedly connected with the outer side of the air drying box (2), a plurality of equidistant activated carbon filter layers (17) are arranged inside the filter cartridge (14), a pipeline is fixedly connected with an upper air outlet of the filter cartridge (14), an exhaust fan (16) is fixedly connected with the other end of the pipeline, and the exhaust fan (16) is fixedly connected with the outer side of the air drying box (2).

5. The clinical laboratory sample preparation device according to claim 1, wherein rectangular clamping grooves are formed in the air drying box (2) and the processing box (4), a moving frame (18) is clamped inside the rectangular clamping grooves, supporting rods (19) are fixedly connected to the moving frame (18), and a plurality of equidistant placement components are arranged on the supporting rods (19).

6. The clinical laboratory sample preparation device according to claim 5, wherein the storage component comprises a storage rack (20) and an overhead disk (21), two symmetrical round holes are formed in the storage rack (20), a support rod (19) is fixedly connected with the inside of the round holes, a vertical rod (22) is fixedly connected onto the storage rack (20), the overhead disk (21) is located right above the vertical rod (22), and hexagonal grooves are formed in the upper end of the vertical rod (22) and the lower side of the overhead disk (21).

7. The clinical laboratory specimen preparation device according to claim 5, wherein three struts (23) are fixedly connected to the outside of said top-mounted disk (21) at equal intervals in the circumference, the top ends of the three struts (23) are fixedly connected to a pressure plate (24), and the upper side of the top-mounted disk (21) is fixedly connected to a connecting plate (25).

8. The preparation device of clinical laboratory's sample according to claim 7, characterized in that, the other end fixedly connected with inserted bar (26) of connecting plate (25), the bottom fixedly connected with disc boss of inserted bar (26), and the upside fixedly connected with of supporter (20) stands a section of thick bamboo (27), the column recess has been seted up to the inside of standing a section of thick bamboo (27), disc boss and the column recess inside swing joint of standing a section of thick bamboo (27) on inserted bar (26), the downside fixedly connected with reset spring (28) of disc boss, the other end of reset spring (28) and the column recess inside fixed connection of standing a section of thick bamboo (27).

9. The clinical laboratory sample preparation device according to claim 5, wherein a plurality of the placement components are provided with a sample placement component therebetween, the sample placement component comprises a connection disc (29) and three sample discs (31), a circular hole is formed in the connection disc (29), a limiting rod (30) is fixedly connected to the inner wall of the circular hole, hexagonal convex blocks are fixedly connected to the upper end and the lower end of the limiting rod (30), and the upper hexagonal convex block and the lower hexagonal convex block are movably connected with hexagonal grooves in a vertical rod (22) and an overhead disc (21) respectively.

10. The preparation device for the clinical laboratory sample according to claim 9, wherein three sample trays (31) are fixedly connected with the connection tray (29), the three sample trays (31) are distributed equidistantly along a circumference, the three sample trays (31) are provided with leakage grooves (32), the three sample trays (31) are provided with a plurality of suspended protrusions (33) inside, a grid pad (34) is arranged above each of the three sample trays (31), and the grid pad (34) is fixedly connected with the upper sides of the suspended protrusions (33).