Sterile concentration equipment for biological medicine research and development
Technical Field
The invention relates to the technical field of medical concentration equipment, in particular to sterile concentration equipment for biological medicine research and development.
Background
In the research and development of medicines, the medicines are required to be concentrated, and the medicines with better efficacy are extracted, wherein the important concentration treatment is to concentrate and extract active ingredients in raw materials or part of raw materials through equipment to prepare clear paste or extract, and the concentration and extraction of the clear paste or extract are mostly realized by adopting ultralow-temperature vacuum concentration equipment.
However, current ultra-low temperature concentrator first need adopt two filter equipment to filter the chinese-medicinal material after the decoction when the concentration of chinese-medicinal material is refined, thereby carry the inside to concentrated jar with the liquid medicine after filtering, and then realize the concentration to the heating concentration processing realization liquid medicine of liquid medicine through concentrated jar, but this kind of mode is when using, need additionally adopt filter equipment to realize filtering the chinese-medicinal material, it not only makes holistic area of device great, needs longer chinese-medicinal material to decoct simultaneously, lead to the holistic concentrating time of medicinal material longer, and unable assurance chinese-medicinal material obtains fully diluting, make the concentration of chinese-medicinal material liquid medicine reduce, its device appears the medicinal material easily when using dilutes incompletely, lead to the medicinal material extravagant, make the concentration of liquid medicine not up to standard simultaneously, and whole operation comes greatly increased holistic operating duration, influence the concentrated quality of medicinal material when reducing work efficiency, therefore need to design a sterile concentrating device for biological medicine research and development to solve above-mentioned problem.
Disclosure of Invention
The invention aims to provide sterile concentration equipment for biological medicine research and development, which aims to solve the problems that in the background technology, the device is easy to dilute medicinal materials thoroughly, so that the medicinal materials are wasted, the concentration of the medicinal liquid is not up to standard, the whole working time is greatly prolonged due to the whole operation, the working efficiency is reduced, and the concentration quality of the medicinal materials is influenced.
In order to achieve the above purpose, the present invention provides the following technical solutions: a sterile concentrating apparatus for biomedical development comprising:
a concentrating tank, wherein one side of the concentrating tank is connected with a separator, the other side of the separator is provided with a condenser, and a liquid receiving tank is connected below the condenser;
the stirring assembly comprises a motor, the motor is connected above the concentration tank, the output end of the motor is connected with a driving shaft through a coupling, a first gear is fixedly connected to the outside of the driving shaft, a second gear is meshed with one side of the first gear, a first driven shaft penetrates through the center of the second gear, a third gear is meshed with the other side of the first gear, and a second driven shaft penetrates through the center of the third gear;
the filter assembly comprises a filter plate, the filter plate is arranged in a concentration tank, a supporting sleeve is connected to the center of the bottom of the filter plate, a limiting sleeve is connected to the center upper portion of the filter plate, a rotating clamping ring is connected to the upper portion of the limiting sleeve, an auger is arranged at the center of the rotating clamping ring and the center of the limiting sleeve, a dispersing plate is movably connected to the outer portion of the rotating clamping ring, a guide plate is arranged on the outer portion of the dispersing plate, a guide column is fixedly connected to the upper portion of the dispersing plate, and a fixing sleeve is connected to the upper portion of the guide column.
Preferably, the concentrating tank comprises a tank body, a sealing cover is arranged above the tank body, a hand hole is arranged above the sealing cover, a first connecting pipe and a second connecting pipe are arranged above the sealing cover, and a supporting plate is connected with the lower end of the inner wall of the sealing cover.
Preferably, the bottom of the tank body is provided with a discharge hole, a separator is connected to the upper side of the first connecting pipe through a conduit, a return pipe is arranged below the separator, the other end of the return pipe penetrates into the tank body, the outer portion of the second connecting pipe is connected with a conveying pipe, and a supporting frame is arranged at the bottom of the tank body.
Preferably, the hand hole comprises a bottom ring, the bottom ring is fixedly connected to the upper portion of the sealing cover, an upper ring is movably connected to the upper portion of the bottom ring through a hinge, a viewing mirror is arranged at the center of the upper ring, a threaded rod is arranged below the bottom ring, and a threaded sleeve is connected to the upper portion of the threaded rod.
Preferably, the bottom ring is rotationally connected with the threaded rod through the rotating support, the threaded rod is in meshing connection with the lower half part of the threaded sleeve, the upper half part of the threaded sleeve is in a circular ring shape, the edge of the upper ring is provided with a positioning groove, the size of the positioning groove is matched with the outer diameter of the threaded rod, and the threaded rod and the threaded sleeve are circumferentially distributed at the edges of the bottom ring and the upper ring.
Preferably, the driving shaft is connected with the supporting plate through a ball bearing, the first driven shaft is connected with the supporting plate through a ball bearing, the second driven shaft is connected with the supporting plate through a ball bearing, the length of the driving shaft is longer than that of the first driven shaft and that of the second driven shaft, the bottom of the driving shaft is fixedly connected with a scraping plate, and the outer walls of the first driven shaft and the second driven shaft are fixedly connected with stirring paddles.
Preferably, the filter is the circular cone structure, the through-hole has been seted up to the top of filter, the through-hole has been seted up to the outside of supporting sleeve, the inside fixedly connected with supporting seat of supporting sleeve, and the center of supporting seat runs through there is the driving shaft, the guiding gutter has been seted up on the limit sleeve near one side of filter, it is step form with the limit sleeve to rotate the snap ring.
Preferably, the bottom of the dispersing plate is provided with a lantern ring, the inner wall of the lantern ring is connected with the rotating snap ring through a ball bearing, the upper surfaces of the guide plate and the dispersing plate are inclined, two through holes are formed in the guide plate, a first driven shaft and a second driven shaft are connected inside the two through holes through the ball bearing, a circular ring guide rail is arranged on the outer wall of the guide plate, a circular ring sliding groove is arranged on the outer wall of the dispersing plate, and the guide plate is connected with the dispersing plate in a rotating mode through the circular ring guide rail and the circular ring sliding groove.
Preferably, the guide post passes through spliced pole fixed connection at the lower surface of fixed cover, fixed cover fixed connection is in the outside of driving shaft, guide post fixed connection is at the upper surface of dispersion board, the guide post is the slope form, auger fixed connection is in the outside of driving shaft, and the auger is in between support sleeve and the fixed cover.
Preferably, the scraping plate is arc-shaped, four groups of stirring paddles are arranged in total, each stirring paddle comprises a fixed ring and stirring teeth, and the angle of each stirring tooth is inclined.
Compared with the prior art, the invention has the beneficial effects that:
1. this sterile concentration equipment for biomedical research and development passes through the filter subassembly that sets up, realize the filtration to the medicinal material through the filter, further drive the auger through the driving shaft and rotate, can realize carrying out spiral to the medicinal material that drops the bottom and rise, and then realize the removal to the medicinal material, simultaneously through the normal running fit of dispersion board and water conservancy diversion post, can realize carrying out circumference rotation distribution to the medicinal material that rises and drop, and then improve the dispersibility of medicinal material, so that the dispersion flow of medicinal material has been realized reciprocally, thereby make when carrying out the concentration of medicinal material, can effectually realize the filtration of chinese medicinal material, reduce outside filtration process, further reduced the holistic area of device, and simultaneously through the reduction of process, can further realize the reduction of operating duration, improve the whole work efficiency of medicinal material.
2. This sterile concentration equipment sets up's filter equipment for biological medicine research and development, realize the filtration to the medicinal material through the filter, further drive the auger through the driving shaft and rotate, can realize rising the medicine that drops the bottom spiral, and then realize the removal to the medicinal material, simultaneously through the normal running fit of dispersion board and water conservancy diversion post, can realize carrying out circumference rotation distribution to rising the medicinal material that drops, and then improve the dispersibility of medicinal material, with this reciprocal dispersed flow that has realized the medicinal material, and then when the liquid medicine heating concentration of below, the in-process that its produced vapor carries out the secondary round heating to the medicinal material of top, make it obtain abundant dilution, and flow into in the below liquid medicine again with the liquid that the medicinal material contacted and mixed, thereby the effectual concentration of concentrated liquid medicine of below that has guaranteed, and the dispersed process of rising can guarantee the dispersion extension of chinese-medicinal material, and then guaranteed the mobility of chinese-medicinal material, make it can evenly be heated and dilute, further improve the make full use of chinese medicinal material, thereby use mutually supporting through its, can carry out filtration at the chinese medicinal material, concentrated quality and working efficiency of medicinal material have been improved, greatly reduced working time.
Drawings
FIG. 1 is a schematic view of the overall structure of the interior of the concentrating tank of the present invention;
FIG. 2 is a schematic diagram of the overall structure of the present invention;
FIG. 3 is an enlarged schematic view of the structure of FIG. 2A according to the present invention;
FIG. 4 is a schematic view of the partial overall structure of the concentrating tank of the present invention;
FIG. 5 is a schematic view of an exploded view of a filter assembly according to the present invention;
FIG. 6 is an enlarged schematic view of the structure of FIG. 5B in accordance with the present invention;
FIG. 7 is a schematic view of the overall structure of the filter assembly of the present invention;
FIG. 8 is a schematic view of the overall structure of the stirring assembly of the present invention.
In the figure: 1. a concentrating tank; 11. a tank body; 12. sealing cover; 13. a hand hole; 31. a bottom ring; 32. a ring is arranged; 33. a viewing mirror; 34. a hinge; 35. a threaded rod; 36. a thread sleeve; 14. a first connection pipe; 15. a second connection pipe; 16. a support plate; 2. a separator; 3. a condenser; 4. a liquid receiving tank; 5. a stirring assembly; 51. a motor; 52. a coupling; 53. a driving shaft; 54. a first gear; 55. a second gear; 56. a first driven shaft; 57. a third gear; 58. a second driven shaft; 6. a filter assembly; 61. a filter plate; 62. a support sleeve; 63. a limit sleeve; 64. rotating the snap ring; 65. an auger; 66. a deflector; 67. a dispersion plate; 68. a flow guiding column; 69. a fixed sleeve; 7. a scraper; 8. stirring paddles.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-8, an embodiment of the present invention is provided:
a sterile concentrating apparatus for biomedical development comprising: the concentration tank 1, the separator 2, the condenser 3 and the liquid receiving tank 4 used in the present application are all commercially available products, and the principle and the connection manner are all well known to those skilled in the art, so that they are not described in detail herein,
a concentrating tank 1, wherein one side of the concentrating tank 1 is connected with a separator 2, the other side of the separator 2 is provided with a condenser 3, and a liquid receiving tank 4 is connected below the condenser 3;
the stirring assembly 5, the stirring assembly 5 includes the motor 51, the motor 51 is connected above the concentration tank 1, the output end of the motor 51 is connected with the driving shaft 53 through the coupling 52, the outside fixedly connected with first gear 54 of driving shaft 53, one side of first gear 54 meshes with second gear 55, the center of second gear 55 runs through first driven shaft 56, the opposite side of first gear 54 meshes with third gear 57, the center of third gear 57 runs through second driven shaft 58, start through the coupling 52, can drive the driving shaft 53 to rotate through the coupling 52, the driving shaft 53 can drive the first gear 54 to rotate while rotating, further can realize the rotation of second gear 55 and third gear 57 through first gear 54, further drive the rotation of first driven shaft 56 and second driven shaft 58, further can drive the scraper 7 and stirring rake 8 to rotate through first driven shaft 56 and second driven shaft 58, can realize stirring the inside the liquid medicine of the tank 11, guarantee the mobility of the liquid medicine inside the tank, avoid influencing the quality of the medicinal material after concentrating, thus through the arrangement of the structure, guarantee the mobility of the liquid medicine inside the liquid medicine after concentrating more even;
the filter subassembly 6, filter subassembly 6 includes filter 61, filter 61 sets up in the inside of concentrate jar 1, filter 61 bottom center is connected with support sleeve 62, the center top of filter 61 is connected with stop collar 63, the top of stop collar 63 is connected with rotates snap ring 64, the center of rotation snap ring 64 and stop collar 63 is provided with auger 65, the outside swing joint of rotation snap ring 64 has dispersion plate 67, the outside of dispersion plate 67 is provided with guide plate 66, the top fixedly connected with guide post 68 of dispersion plate 67, the top of guide post 68 is connected with fixed cover 69, rotation through driving shaft 53 can drive auger 65 and fixed cover 69 and rotate, further realize the filtration of chinese medicinal material through filter 61, further drop to the inside medicinal material of support sleeve 62 can be through the spiral of auger 65 from down to the top, and drop to the top of dispersion plate 67, and the dispersion plate 67 rotates through the rotation of fixed cover 69, can realize carrying out circumference dispersion rotation to the medicinal material that drops above dispersion plate 67, further through the guide plate 66 drops to the top of filter 61, and through the flow of medicinal material, make the inside of the jar body 11 when carrying out the heating efficiency, the medicine can be greatly reduced, the medicine can be further be heated, the medicine can be more effectively diluted and the inside the medicine can be more effectively cooled, the medicine can be guaranteed, the inside is more than the medicine can be more effectively cooled.
Further, the concentration tank 1 comprises a tank body 11, a sealing cover 12 is arranged above the tank body 11, a hand hole 13 is arranged above the sealing cover 12, a first connecting pipe 14 and a second connecting pipe 15 are arranged above the sealing cover 12, and a supporting plate 16 is connected to the lower end of the inner wall of the sealing cover 12 and used for heating concentration treatment of medicinal materials.
Further, the bottom of the tank 11 is provided with a discharge port, the separator 2 is connected to the upper side of the first connecting pipe 14 through a conduit, a return pipe is arranged below the separator 2, the other end of the return pipe penetrates through the tank 11, the second connecting pipe 15 is externally connected with a conveying pipe, and a supporting frame is arranged at the bottom of the tank 11 and used for supporting the tank 11 in an auxiliary mode.
Further, hand hole 13 includes bottom ring 31, and bottom ring 31 fixed connection is in the top of sealed lid 12, and hinge 34 swing joint is passed through to the top of bottom ring 31 has upper ring 32, and the center of upper ring 32 is provided with sight glass 33, and the below of bottom ring 31 is provided with threaded rod 35, and the top of threaded rod 35 is connected with threaded sleeve 36, is convenient for observe to the inside of jar body 11, and adopts the mode of spiral block, and the simple operation compares the bolt installation, and later use is more convenient.
Further, the bottom ring 31 is rotationally connected with the threaded rod 35 through the rotating support, the threaded rod 35 is in meshed connection with the lower half part of the threaded sleeve 36, the upper half part of the threaded sleeve 36 is annular, the edge of the upper ring 32 is provided with a positioning groove, the size of the positioning groove is matched with the outer diameter of the threaded rod 35, the threaded rod 35 and the threaded sleeve 36 are circumferentially distributed on the edges of the bottom ring 31 and the upper ring 32, the threaded rod 35 is rotated to enable the threaded rod 35 to be clamped on the edge of the upper ring 32, the threaded sleeve 36 is further rotated, and the upper ring 32 can be fixed through extrusion of the threaded sleeve 36.
Further, driving shaft 53 passes through ball bearing and backup pad 16 interconnect, and first driven shaft 56 passes through ball bearing and backup pad 16 interconnect, and second driven shaft 58 passes through ball bearing and backup pad 16 interconnect, reduces frictional force, improves the rotation efficiency of three, and the length of driving shaft 53 is longer than the length of first driven shaft 56 and second driven shaft 58, and the bottom fixedly connected with scraper blade 7 of driving shaft 53, and the outer wall fixedly connected with stirring rake 8 of first driven shaft 56 and second driven shaft 58, through the rotation of scraper blade 7 and stirring rake 8, realizes stirring the inside liquid medicine of jar body 11.
Further, the filter 61 is the circular cone structure, the through-hole has been seted up to the top of filter 61, the filtration of the liquid of being convenient for, the through-hole has been seted up to the outside of supporting sleeve 62 for the filtration of liquid, the inside fixedly connected with supporting seat of supporting sleeve 62, and the center of supporting seat runs through there is driving shaft 53, further auxiliary support for driving shaft 53, improve driving shaft 53 pivoted stability, realize simultaneously blocking the medicinal material, the guiding gutter has been seted up on one side of stop collar 63 near filter 61, the medicinal material of being convenient for drops to the top of auger 65, rotate snap ring 64 and stop collar 63 are the step form.
Further, the bottom of the dispersing plate 67 is provided with the lantern ring, and the inner wall of the lantern ring is connected with the rotating snap ring 64 through the ball bearing, so that the rotation stability of the dispersing plate 67 is improved, friction is reduced, the upper surfaces of the guide plate 66 and the dispersing plate 67 are inclined, the guide of medicinal materials is facilitated, two through holes are formed in the guide plate 66, the first driven shaft 56 and the second driven shaft 58 are connected through the ball bearing in the two through holes, the outer wall of the guide plate 66 is provided with the circular ring guide rail, the circular ring sliding groove is formed in the outer wall of the dispersing plate 67, and the guide plate 66 and the dispersing plate 67 are in rotation connection through the circular ring guide rail and the circular ring sliding groove, so that the rotation stability of the dispersing plate 67 is further improved.
Further, guide post 68 passes through spliced pole fixed connection at the lower surface of fixed cover 69, fixed cover 69 fixed connection is in the outside of driving shaft 53, guide post 68 fixed connection is at the upper surface of dispersion board 67, guide post 68 is the slope form, auger 65 fixed connection is in the outside of driving shaft 53, and auger 65 is in between support cover 62 and the fixed cover 69, rotate through fixed cover 69, can drive guide post 68 and dispersion board 67 through the spliced pole, and set up through the slope of guide post 68, can realize the rotation direction to the medicinal material, make it be circumference to dispersing all around, and through the setting of different positions, can realize the circumference distribution of medicinal material when dispersion board 67 rotates, guarantee the even of its dispersion.
Further, scraper 7 is circular-arc, and stirring rake 8 is provided with four sets of altogether, and stirring rake 8 includes solid fixed ring and stirring tooth, and the angle of stirring tooth is the slope form, reduces the resistance, is convenient for stir the liquid medicine.
Working principle: when the traditional Chinese medicine decocting device is used, firstly decocted traditional Chinese medicines are conveyed into the tank 11, filtering of medicinal materials in the traditional Chinese medicines can be further achieved through the filter plate 61, medicinal liquid is filtered to the bottom of the tank 11, concentration treatment of the medicinal liquid in the tank 11 is further achieved through heating of the tank 11, the medicinal liquid is more uniformly mixed by means of working of the stirring assembly 5 in the earlier stage of heating, local precipitation and the like are avoided, the driving shaft 53 can be driven to rotate through the coupler 52 when the motor 51 is started, the second gear 55 and the third gear 57 can be further driven to rotate through the first gear 54, the first driven shaft 56 and the second driven shaft 58 are further driven to rotate, the scraper 7 and the stirring paddle 8 below are driven to rotate, and the medicinal liquid is rotated, so that the mixing uniformity of the medicinal liquid is guaranteed.
Can drive auger 65 when driving shaft 53 rotates and rotate, further can make the medicinal material that drops to the inside of supporting sleeve 62 upwards carry, and then can carry the medicinal material from lower supreme through auger 65's rotation, and carry the medicinal material of top to drop the top of dispersion board 67, further drive fixed cover 69 through driving shaft 53 and rotate, can drive dispersion board 67 and guide post 68 and rotate, further make the medicinal material that drops to dispersion board 67 top realize circumference dispersion through guide post 68, and the top of landing to guide plate 66, further drop the top to filter 61, with this reciprocal, the flow of medicinal material has been realized.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential characteristics thereof. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.