CN115282184A - 一种治癣外用软膏 - Google Patents
一种治癣外用软膏 Download PDFInfo
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- CN115282184A CN115282184A CN202211032865.7A CN202211032865A CN115282184A CN 115282184 A CN115282184 A CN 115282184A CN 202211032865 A CN202211032865 A CN 202211032865A CN 115282184 A CN115282184 A CN 115282184A
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- treating tinea
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Abstract
本发明涉及癣药膏技术领域,具体是一种治癣外用软膏,包括如下重量的成分:珍珠贝3克、珊瑚3克、钟乳石3克、薄荷15克、牡蛎壳3克、樟脑6克、龙骨3克、珍珠3克、玛瑙3克、熊胆粉3克、纯鸸鹋油500克、菊花10克、决明子6克、冰片6克、茯苓6克。本发明用料考究、配比科学,通过各成分之间的协同作用,具有较佳的抗菌、抑菌效果,在针对金黄色葡萄球菌、大肠杆菌、白色念珠菌引起的皮肤病具有快速治愈的作用,同时可以对促进皮肤修复、清洁滋养,使得皮肤恢复后更加光洁。
Description
技术领域
本发明涉及癣药膏技术领域,具体是一种治癣外用软膏。
背景技术
皮癣可分为头癣、手癣、足癣、股癣等,是由真菌感染引起的一种传染性皮肤病,临床常用药膏涂抹治疗。
经检索,中国专利申请号200710060592.6公开了“一种治疗癣病的外用中成药”,旨在解决解决现有治疗癣病药物治疗效果差、且又时常复发的问题。它所含药剂成份及重量配比为:斑蝥26~34份、川辣子180~220份、蜈蚣20~36份、土槿皮260~330份、樟脑260~342份、白矾350~430份、雄黄380~412份、蛇床子140~158份,再按上述重量配比用白酒5000~10000份浸泡,精制成的外用治癣中成药,其配方合理,治疗效果明显,既治标又治本,适用于治疗干湿癣、牛皮癣、头癣、手癣、足癣、红癣、圆癣等癣病,但是该专利抑菌效果较差,因此针对真菌感染的皮癣疗效慢。因此,本领域技术人员提供了一种治癣外用软膏,以解决上述背景技术中提出的问题。
发明内容
本发明的目的在于提供一种治癣外用软膏,以解决上述背景技术中提出的问题。
为实现上述目的,本发明提供如下技术方案:一种治癣外用软膏,包括如下重量的成分:珍珠贝2—5克、珊瑚2—5克、钟乳石2—5克、薄荷13—18克、牡蛎壳1—3克、樟脑3—6克、龙骨2—5克、珍珠1—3克、玛瑙1—3克、熊胆粉2—5克、纯鸸鹋油400—500克、菊花5—10克、决明子3—6克、冰片3—6克、茯苓3—6克。
作为本发明更进一步的方案:包括如下重量的成分:珍珠贝3克、珊瑚3克、钟乳石3克、薄荷15克、牡蛎壳3克、樟脑6克、龙骨3克、珍珠3克、玛瑙3克、熊胆粉3克、纯鸸鹋油500克、菊花10克、决明子6克、冰片6克、茯苓6克。
作为本发明更进一步的方案:治癣外用软膏,由以下方法制备:
S1:将珍珠贝、珊瑚、钟乳石、薄荷、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、菊花、决明子、冰片、茯苓清洗干净后、晾干备用;
S2:将晾干后的茯苓、薄荷、珊瑚以及菊花进行冻干处理;
S3:冻干处理后的茯苓、薄荷、珊瑚以及菊花与珍珠贝、钟乳石、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、决明子、冰片一起破碎、过筛、混合制得混合药粉;
S4:将混合药粉与纯鸸鹋油混合搅拌成膏状,即制得治癣外用软膏。
作为本发明更进一步的方案:将S4制得的治癣外用软膏涂抹于药贴上,即可得到治癣外用膏贴。
作为本发明更进一步的方案:S3中过筛采用铜网,铜网的网孔为100—200目。
作为本发明更进一步的方案:S2中冻干处理的具体步骤如下:
A1:将茯苓、薄荷、珊瑚以及菊花置入冷冻箱进行急速冷冻,急速冷冻的温度为-20—-25℃;
A2:将急速冷冻后的茯苓、薄荷、珊瑚以及菊花进行真空冷冻干燥。
作为本发明更进一步的方案:真空冷冻干燥包括冷冻干燥和解析干燥:冷冻干燥时:真空度25—30Pa、冷阱温度为-40—-45℃、升华温度50—60℃、时长3—6h;
解析干燥时:真空度10—15Pa、干燥温度35—40℃、时长3—6h。
各成分药效分析
珍珠贝:安神定惊、清热功能;
珊瑚:安神镇静、止血明目、敛疮止血;
钟乳石:助阳、赛痰咳喘、阳虚冷喘、腰膝冷痛、乳汁不通;
牡蛎壳:归肝经、胆经和肾经、安神育阳、促进代谢、排出体内毒素;
樟脑:通关窍、强心、杀虫止痒;
龙骨:平肝潜阳、收敛固涩、镇惊安神;
珍珠:皮肤溃烂、心虚健忘;
玛瑙:性寒、清热解毒、明目除障、改善赤烂症状;
熊胆粉:平肝、清热、明目、缓解皮炎、惊风抽搐,对癣病皮肤有修复功效;
鸸鹋油:消炎止痛、排风湿、清热解毒、缓解炎症、清热解毒;
菊花:降血压、明目、提神;
决明子:清热解毒、缓解便秘、清肝明目;
冰片:通窍、散郁火、消肿止痛、热病神昏、解毒;
茯苓:利水渗湿、养心安神;
薄荷:疏散风热、解毒透疹、清利头目。
与现有技术相比,本发明的有益效果是:本发明用料考究、配比科学,通过各成分之间的协同作用,具有较佳的抗菌、抑菌效果,在针对金黄色葡萄球菌、大肠杆菌、白色念珠菌引起的皮肤病具有快速治愈的作用,同时可以对促进皮肤修复、清洁滋养,使得皮肤恢复后更加光洁。
具体实施方式
本发明实施例中,一种治癣外用软膏,包括如下重量的成分:珍珠贝2克、珊瑚5克、钟乳石5克、薄荷13克、牡蛎壳3克、樟脑6克、龙骨2克、珍珠1克、玛瑙1克、熊胆粉5克、纯鸸鹋油400克、菊花5克、决明子3克、冰片6克、茯苓3克。
进一步的,治癣外用软膏由以下方法制备:
S1:将珍珠贝、珊瑚、钟乳石、薄荷、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、菊花、决明子、冰片、茯苓清洗干净后、晾干备用;
S2:将晾干后的茯苓、薄荷、珊瑚以及菊花进行冻干处理;
S3:冻干处理后的茯苓、薄荷、珊瑚以及菊花与珍珠贝、钟乳石、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、决明子、冰片一起破碎、过筛、混合制得混合药粉;
S4:将混合药粉与纯鸸鹋油混合搅拌成膏状,即制得治癣外用软膏。
进一步的,将S4制得的治癣外用软膏涂抹于药贴上,即可得到治癣外用膏贴。
进一步的,S3中过筛采用铜网,铜网的网孔为200目。
进一步的,S2中冻干处理的具体步骤如下:
A1:将茯苓、薄荷、珊瑚以及菊花置入冷冻箱进行急速冷冻,急速冷冻的温度为-25℃;
A2:将急速冷冻后的茯苓、薄荷、珊瑚以及菊花进行真空冷冻干燥。
进一步的,真空冷冻干燥包括冷冻干燥和解析干燥:冷冻干燥时:真空度30Pa、冷阱温度为-45℃、升华温度60℃、时长4h;
解析干燥时:真空度15Pa、干燥温度40℃、时长4.5h。
实施例2
本实施例中,一种治癣外用软膏,其特征在于,包括如下重量的成分:珍珠贝3克、珊瑚3克、钟乳石3克、薄荷15克、牡蛎壳3克、樟脑6克、龙骨3克、珍珠3克、玛瑙3克、熊胆粉3克、纯鸸鹋油500克、菊花10克、决明子6克、冰片6克、茯苓6克。
进一步的,治癣外用软膏,由以下方法制备:
S1:将珍珠贝、珊瑚、钟乳石、薄荷、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、菊花、决明子、冰片、茯苓清洗干净后、晾干备用;
S2:将晾干后的茯苓、薄荷、珊瑚以及菊花进行冻干处理;
S3:冻干处理后的茯苓、薄荷、珊瑚以及菊花与珍珠贝、钟乳石、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、决明子、冰片一起破碎、过筛、混合制得混合药粉;
S4:将混合药粉与纯鸸鹋油混合搅拌成膏状,即制得治癣外用软膏。
进一步的,将S4制得的治癣外用软膏涂抹于药贴上,即可得到治癣外用膏贴。
进一步的,S3中过筛采用铜网,铜网的网孔为100目。
进一步的,S2中冻干处理的具体步骤如下:
A1:将茯苓、薄荷、珊瑚以及菊花置入冷冻箱进行急速冷冻,急速冷冻的温度为-20—-25℃;
A2:将急速冷冻后的茯苓、薄荷、珊瑚以及菊花进行真空冷冻干燥。
进一步的,真空冷冻干燥包括冷冻干燥和解析干燥:冷冻干燥时:真空度25Pa、冷阱温度为-40℃、升华温度50℃、时长3h;
解析干燥时:真空度10Pa、干燥温度35℃、时长3h。
测试例1
测试组别:实施例1、实施例2、对比例(市面上常见的同类产品);
测试方法:参照QB/T2591-2003用贴膜法,考察3组产品48h的抑菌率,菌落总数的策动参照GB/T4789.2-2003计数;
抑菌率公式P(%)=(A-B)/C×100,其中:P为抗菌率、A为空白对照样品平均回收菌数,cfu/片;B为产品样品平均回收菌数,cfu/片;
测试结果
金黄色葡萄球菌% | 大肠杆菌% | 白色念珠菌% | |
实施例1 | 99.83 | 99.65 | 99.72 |
实施例2 | 98.58 | 98.92 | 97.63 |
对比例 | 72.81 | 76.83 | 85.42 |
结合测试例1的测试结果可以明显得出本申请实施例1和实施例2具有较佳的抑菌效果,针对金黄色葡萄球菌、大肠杆菌、白色念珠菌引起的皮肤病具有快速治愈的作用,反观对比例,效果较差。
测试例2
测试组别:实施例1、实施例2、对比例(市面上常见的同类产品);
测试人员:征选150人名癣病患者(18-65周岁),分成3组;
测试方法:每组患者每天分别涂抹3个组别的产品,每天涂抹两次,7天为一个疗程,一个疗程结束后统计治愈情况;
测试结果
治愈 | 显效 | 无效 | 有效率 | |
实施例1 | 43 | 7 | 0 | 100% |
实施例2 | 35 | 15 | 0 | 100% |
对比例 | 13 | 24 | 13 | 67% |
结合上述数据可以明显看出,本申请实施例1、实施例2具有较高的癣病治愈效果,相反对比例的治愈效果反应平平。
综上所述:本发明用料考究、配比科学,通过各成分之间的协同作用,具有较佳的抗菌、抑菌效果,在针对金黄色葡萄球菌、大肠杆菌、白色念珠菌引起的皮肤病具有快速治愈的作用,同时可以对促进皮肤修复、清洁滋养,使得皮肤恢复后更加光洁。
以上所述的,仅为本发明较佳的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,根据本发明的技术方案及其发明构思加以等同替换或改变,都应涵盖在本发明的保护范围之内。
Claims (7)
1.一种治癣外用软膏,其特征在于,包括如下重量的成分:珍珠贝2—5克、珊瑚2—5克、钟乳石2—5克、薄荷13—18克、牡蛎壳1—3克、樟脑3—6克、龙骨2—5克、珍珠1—3克、玛瑙1—3克、熊胆粉2—5克、纯鸸鹋油400—500克、菊花5—10克、决明子3—6克、冰片3—6克、茯苓3—6克。
2.根据权利要求1所述的一种治癣外用软膏,其特征在于,包括如下重量的成分:珍珠贝3克、珊瑚3克、钟乳石3克、薄荷15克、牡蛎壳3克、樟脑6克、龙骨3克、珍珠3克、玛瑙3克、熊胆粉3克、纯鸸鹋油500克、菊花10克、决明子6克、冰片6克、茯苓6克。
3.根据权利要求1-2任一项所述的一种治癣外用软膏,其特征在于,由以下方法制备:
S1:将珍珠贝、珊瑚、钟乳石、薄荷、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、菊花、决明子、冰片、茯苓清洗干净后、晾干备用;
S2:将晾干后的茯苓、薄荷、珊瑚以及菊花进行冻干处理;
S3:冻干处理后的茯苓、薄荷、珊瑚以及菊花与珍珠贝、钟乳石、牡蛎壳、樟脑、龙骨、珍珠、玛瑙、决明子、冰片一起破碎、过筛、混合制得混合药粉;
S4:将混合药粉与纯鸸鹋油混合搅拌成膏状,即制得治癣外用软膏。
4.根据权利要求3所述的一种治癣外用软膏,其特征在于,将S4制得的治癣外用软膏涂抹于药贴上,即可得到治癣外用膏贴。
5.根据权利要求3所述的一种治癣外用软膏,其特征在于,S3中过筛采用铜网,铜网的网孔为100—200目。
6.根据权利要求3所述的一种治癣外用软膏,其特征在于,S2中冻干处理的具体步骤如下:
A1:将茯苓、薄荷、珊瑚以及菊花置入冷冻箱进行急速冷冻,急速冷冻的温度为-20—-25℃;
A2:将急速冷冻后的茯苓、薄荷、珊瑚以及菊花进行真空冷冻干燥。
7.根据权利要求6所述的一种治癣外用软膏,其特征在于,真空冷冻干燥包括冷冻干燥和解析干燥:冷冻干燥时:真空度25—30Pa、冷阱温度为-40—-45℃、升华温度50—60℃、时长3—6h;
解析干燥时:真空度10—15Pa、干燥温度35—40℃、时长3—6h。
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