CN115253762A - Active carbon oral pill, preparation device and preparation method - Google Patents
Active carbon oral pill, preparation device and preparation method Download PDFInfo
- Publication number
- CN115253762A CN115253762A CN202211035923.1A CN202211035923A CN115253762A CN 115253762 A CN115253762 A CN 115253762A CN 202211035923 A CN202211035923 A CN 202211035923A CN 115253762 A CN115253762 A CN 115253762A
- Authority
- CN
- China
- Prior art keywords
- active carbon
- honey
- activated carbon
- pill
- air
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 title claims abstract description 101
- 229910052799 carbon Inorganic materials 0.000 title claims abstract description 53
- 239000006187 pill Substances 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 235000012907 honey Nutrition 0.000 claims abstract description 29
- 239000002245 particle Substances 0.000 claims abstract description 17
- 238000003756 stirring Methods 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 14
- 238000007789 sealing Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 238000005096 rolling process Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 2
- 229940095352 oral pellet Drugs 0.000 claims description 2
- 238000002156 mixing Methods 0.000 abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 230000001681 protective effect Effects 0.000 abstract description 3
- 210000002784 stomach Anatomy 0.000 abstract description 3
- 239000003053 toxin Substances 0.000 abstract description 3
- 231100000765 toxin Toxicity 0.000 abstract description 3
- 235000009508 confectionery Nutrition 0.000 abstract description 2
- 238000001784 detoxification Methods 0.000 abstract description 2
- 239000007787 solid Substances 0.000 abstract description 2
- 208000005374 Poisoning Diseases 0.000 description 4
- 231100000572 poisoning Toxicity 0.000 description 4
- 230000000607 poisoning effect Effects 0.000 description 4
- 239000000375 suspending agent Substances 0.000 description 3
- 239000000284 extract Substances 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 206010008428 Chemical poisoning Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/60—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis
- B01F27/70—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a horizontal or inclined axis with paddles, blades or arms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
Abstract
The invention relates to an active carbon oral pill, a preparation device and a preparation method, wherein the active carbon oral pill comprises 50-75 parts by weight of active carbon and 25-50 parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill; also includes a preparation device and a preparation method. According to the active carbon oral pill, the mixing amount of the active carbon can reach 75%, the total volume of the solid oral active carbon required for detoxification is greatly reduced, the active carbon oral pill is uniformly mixed with honey and is wrapped by the honey, a protective film is formed on the surface of active carbon particles, the whole oral pill is relatively moist, relatively smooth and sweet, and can be easily taken with warm water, and the honey is dissolved in water, so that the active carbon can be quickly dispersed in the stomach, and the toxin can be conveniently absorbed.
Description
Technical Field
The invention relates to a medicine, in particular to an active carbon oral pill, a preparation device and a preparation method, which are used for treating human or animals suffering from oral poisoning and adsorbing toxic substances in the stomach and intestine.
Background
In China, pesticide poisoning and drug poisoning occur, the poisoning person takes the oral poisoning way as the most, in the rescue and treatment of acute oral poisoning patients, oral activated carbon is one of basic rescue measures, in the rescue process, the dosage of the activated carbon is about 50 g, in the prior art, tablets and suspending agents are used more, the tablets are difficult to swallow, the suspending agent has limited amount of the activated carbon mixed in unit volume, the mixing proportion is at most 25%, and the volume required by taking the suspending agent is four times of that of the tablets.
The two formulations have respective problems, and how to improve the mixing capacity of the active carbon, and the active carbon is easy to take and disperse to absorb toxins after being taken is a technical problem which needs to be solved urgently.
In order to solve the above problems, people are always seeking an ideal technical solution.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides an active carbon oral pill, a preparation device and a preparation method.
The technical scheme adopted by the invention is as follows:
the active carbon oral pill comprises 50-75 parts by weight of active carbon and 25-50 parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill.
Preparation facilities of active carbon oral pill, including agitator tank and with the vacuum air extractor of agitator tank intercommunication, the agitator tank includes the feed inlet of box, tube-shape, establishes sealed lid, the sealed gear motor who inserts the pivot that has stirring vane and drive pivot on establishing the box soon on the feed inlet, rotates, and the box passes through the connecting pipe and is connected with the vacuum air extractor.
The preparation method for preparing the activated carbon oral pill by using the preparation device comprises the following steps:
step 1, grinding active carbon into active carbon particles of 150-300 meshes; adding honey into the box body, stirring, and gradually adding the ground activated carbon particles with the set weight in the stirring process;
and 3, after stirring is finished, eliminating the air pressure difference between the inside and the outside of the box body, then opening a sealing cover, taking out the mixture, rolling pills and packaging.
Preferably, in step 2, the air suction during the stirring process is divided into two stages, wherein the first stage is used for sucking air and keeping the air pressure at 50kPa for 2 minutes, then the difference between the internal air pressure and the external air pressure is eliminated, the second stage is used for sucking air and keeping the air pressure at 50kPa for 2 minutes.
According to the active carbon oral pill, the mixing amount of the active carbon can reach 75%, the total volume of solid oral active carbon required for detoxification is greatly reduced, the active carbon oral pill is uniformly mixed with honey and is wrapped by the honey, a protective film is formed on the surface of active carbon particles, the whole oral pill is relatively moist, relatively smooth and sweet, and can be taken with warm water easily, and the honey is dissolved in water, so that the active carbon can be dispersed in the stomach quickly, and toxin absorption is facilitated.
According to the preparation method of the active carbon oral pill, in the stirring process of the preparation device, the air in the box body is pumped out by the vacuum air pump to form negative pressure, and the air in the active carbon particles, among the active carbon particles and in bubbles generated in the stirring process is gradually exhausted, so that the honey is gradually and completely wrapped on the surface of the active carbon to form a protective film, and the adsorption capacity of the active carbon particles is ensured.
Drawings
Fig. 1 is a schematic structural diagram of a device for preparing an activated carbon oral pellet in an embodiment of the invention.
Detailed Description
The technical solution of the present invention is further described in detail by the following embodiments.
Example 1
The active carbon oral pill comprises 50KG of active carbon and 25KG of honey by weight, and the active carbon and the honey are mixed to prepare the pill.
Example 2
The active carbon oral pill comprises 50KG parts by weight of active carbon and 50KG parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill.
Example 3
The active carbon oral pill comprises 75KG parts by weight of active carbon and 25KG parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill.
Example 4
The active carbon oral pill comprises 75KG parts by weight of active carbon and 50KG parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill.
Example 5
The active carbon oral pill comprises 50KG of active carbon and 40KG of honey, and the active carbon and the honey are mixed to prepare the pill.
Example 6
Preparation facilities of active carbon oral pill, as shown in fig. 1, including agitator tank and the vacuum air pump 11 with agitator tank intercommunication, the agitator tank includes box 1, feed inlet 9 of tube-shape, establish sealed lid 8 on the feed inlet soon, the sealed pivot 2 that inserts the pivot that has stirring vane 3 and drive the setting of pivot on the mount pad 4 of establishing on the box of rotating, vacuum air pump 11 is through setting up 10 and box intercommunication at the box top, still set up breather pipe 6 on the box 1, set up solenoid valve 7 on the breather pipe, be used for balancing inside and outside air pressure at the stirring end, stirring vane 3 has two sets ofly, set up in opposite directions, when stirring, push the raw materials of both sides to the centre, also carry out extrusion mixing in longitudinal direction.
Example 7
The preparation method for preparing the activated carbon oral pill by using the preparation device comprises the following steps:
step 1, grinding activated carbon into activated carbon particles of 150-300 meshes (200 meshes in the embodiment), adding honey into a box body, stirring, and gradually adding the ground activated carbon particles with a set weight in the stirring process;
and 3, after stirring is finished, eliminating the air pressure difference between the inside and the outside of the box body, then opening the sealing cover, taking out the mixture, rolling pills and packaging.
Preferably, in step 2, the air extraction during the stirring process is divided into two stages, wherein the first stage extracts air and maintains the air pressure at 50kPa for 2 minutes, then the internal and external air pressure difference is eliminated, the second stage is entered, and the second stage extracts air and maintains the air pressure at 50kPa for 2 minutes.
Finally, it should be noted that the above examples are only used to illustrate the technical solutions of the present invention and not to limit the same; although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art will understand that: modifications to the specific embodiments of the invention or equivalent substitutions for parts of the technical features may be made; without departing from the spirit of the present invention, it is intended to cover all aspects of the invention as defined by the appended claims.
Claims (4)
1. The active carbon oral pill is characterized by comprising 50-75 parts by weight of active carbon and 25-50 parts by weight of honey, and the active carbon and the honey are mixed to prepare the pill.
2. Preparation facilities of active carbon oral pill, its characterized in that: including agitator tank and with the vacuum air extractor of agitator tank intercommunication, the agitator tank includes the feed inlet of box, tube-shape, establishes sealed lid, the sealed cover of establishing soon on the feed inlet, rotates that sealed inserts the gear motor who establishes the pivot that has stirring vane and drive pivot on the box, the box passes through the connecting pipe and is connected with the vacuum air extractor.
3. A method for preparing an activated carbon oral pellet using the preparation apparatus of claim 2, characterized by comprising the steps of:
step 1, grinding activated carbon into activated carbon particles of 150-300 meshes; adding honey into the box body, stirring, and gradually adding the ground activated carbon particles with the set weight in the stirring process;
step 2, screwing the sealing cover on the feeding hole to seal tightly, starting a vacuum air extractor to extract air in the box body to form negative pressure, continuing stirring, and gradually discharging air in the activated carbon particles, among the activated carbon particles and in bubbles generated in the stirring process so that the honey is gradually and completely wrapped on the surface of the activated carbon;
and 3, after stirring is finished, eliminating the air pressure difference between the inside and the outside of the box body, then opening a sealing cover, taking out the mixture, rolling pills and packaging.
4. The method for preparing the activated carbon oral pill according to claim 3, characterized in that: in the step 2, the air extraction in the stirring process is divided into two stages, wherein the first stage is used for extracting air and keeping the air pressure at 50kPa for 2 minutes, then the internal and external air pressure difference is eliminated, the second stage is used for extracting air and keeping the air pressure at 50kPa for 2 minutes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211035923.1A CN115253762A (en) | 2022-08-27 | 2022-08-27 | Active carbon oral pill, preparation device and preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211035923.1A CN115253762A (en) | 2022-08-27 | 2022-08-27 | Active carbon oral pill, preparation device and preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115253762A true CN115253762A (en) | 2022-11-01 |
Family
ID=83754926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211035923.1A Pending CN115253762A (en) | 2022-08-27 | 2022-08-27 | Active carbon oral pill, preparation device and preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115253762A (en) |
Citations (17)
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|---|---|---|---|---|
| KR20000062073A (en) * | 1999-03-30 | 2000-10-25 | 이창진 | Aaaaa |
| JP2004337142A (en) * | 2003-05-18 | 2004-12-02 | Shinichi Shioda | Honey containing carbon ceramic |
| JP2006036734A (en) * | 2004-07-30 | 2006-02-09 | Toa Eiyo Ltd | Activated carbon product for oral administration |
| WO2010001485A1 (en) * | 2008-07-04 | 2010-01-07 | 旭有機材工業株式会社 | Adsorbent for oral administration |
| CN103349251A (en) * | 2013-07-31 | 2013-10-16 | 宁夏天瑞产业集团现代农业有限公司 | Bamboo carbon crispy yam ball and manufacture method thereof |
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-
2022
- 2022-08-27 CN CN202211035923.1A patent/CN115253762A/en active Pending
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Effective date of registration: 20231023 Address after: 311300 709, Building 13, Yijiangnan Jiayuan, Jincheng Street, Lin'an District, Hangzhou City, Zhejiang Province Applicant after: Wang Mingqiu Address before: 101100 room 01-1612, 3rd floor, 99 Shuixian West Road, Tongzhou District, Beijing Applicant before: Xipan (Beijing) Information Technology Co.,Ltd. |