CN1081889A - A kind of Chinese medicine oral liquid for lung cancer and production method thereof - Google Patents

A kind of Chinese medicine oral liquid for lung cancer and production method thereof Download PDF

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Publication number
CN1081889A
CN1081889A CN 93100721 CN93100721A CN1081889A CN 1081889 A CN1081889 A CN 1081889A CN 93100721 CN93100721 CN 93100721 CN 93100721 A CN93100721 A CN 93100721A CN 1081889 A CN1081889 A CN 1081889A
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standby
feature
present
pulverizing
powder
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李学新
吴细丕
牛锡民
胡月荣
彭树兰
范锦平
毕海英
李霞
刘海泉
郭凤兰
臧淑梅
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李学新
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Abstract

The present invention is a kind of Chinese medicine oral liquid for lung cancer and production method thereof.This medicine is made up of plurality of Chinese, and its preparation method is, to drug screening, cut into slices, dry, oven dry, parching to brown, roasting, parch to black, pulverizing, porphyrize, pulverize, soak, heat, filter formulated.Be mainly used in the treatment of early, middle and late phase pulmonary carcinoma and respiratory system cancer.Be a kind of having no side effect, no Drug resistance, safe and reliable, curative effect is fast, and taking convenience need not operation, radiotherapy, chemotherapy can cure the desirable cancer therapy drug of cancer.

Description

A kind of Chinese medicine oral liquid for lung cancer and production method thereof
Particularly: the invention belongs to Chinese patent drug and production method thereof.
General DIYU treatment of cancer is used for operation more, radiation exposure and chemotherapy, and it is big to exist side effect, kill and wound leukocyte, health is had considerable influence, life span is short, easily recurrence, operation are only applicable to early, mid-term not the cancer of diffusion transfer and body strong in, young cancer patient.Still there is not at present the directly anticancer Chinese medicine antitumor oral liquid that kills and wounds cancerous cell.
The purpose of this invention is to provide a kind of Chinese medicine oral liquid for lung cancer and production method thereof.Make its treatment pulmonary carcinoma and other cancer of respiratory system, have no side effect, no Drug resistance, safe and reliable, curative effect is fast,, life span is long, and taking convenience need be with not performing the operation, and radiotherapy, chemotherapy all can be treated early, middle and late phase cancer.It is tight good to fill a prescription, and is better than other cancer therapy drug and method through the zoopery contrast, has reached 7 years through clinical observation The average survival time rate.
The main medicine of the present invention is fluffy 5% by Spica Prunellae 10%, half, Flos Lonicerae 4%, Herba Violae 5%, dandelion 10%, cornu saigae tatariace powder 3%, Cornu Bubali 5%, Radix Curcumae 4%, eupolyphaga 2%, Moschus 1%, blood amber 3%, give birth to BOHUANG 3%, Semen Persicae 3%, Stigma Croci 3%, Radix Notoginseng 3%, taro charcoal 5%, medicinal borax 5%, edible nitric acid first 5%, Scorpio 3%, Bombyx Batryticatus 1%, Herba Siegesbeckiae 6%, Radix Platycodonis 2%, Rhizoma Pinelliae 2%, full Fructus Trichosanthis 5%, Radix Glycyrrhizae 2% form.Its preparation method, to drug screening, chopping, dry, dry, pulverize, roasting, parching to brown, pulverize, porphyrize, soak, heat, filtration, formulatedly be " oral liquid for lung cancer " stock solution, the medicinal liquid branch packed into seal in the vial of 50CC, again with per 10 dresses, be arranged in shockproof transparent plastic closes.And be that big case encapsulation promptly becomes " Chinese medicine oral liquid for lung cancer " finished medicines with 30 boxes.
Concoct by medicine processing, change pharmaceutical properties, improve pharmaceutical purity, medicament curative effect enhancement.It is for the effective ingredient of damage medicine not that single medicinal material is concocted, and keeps original performance of medicine.Immersion is in order to extract the effective ingredient of medicine, to reduce survival dose, quickening the performance pharmaceutical efficacy.The purpose that obtains medicinal liquid by herbal medicine immersion retort preparation is for medicinal liquid being contacted with air, avoiding bacterial infection to meet hygienic requirements.
The process of preparing Chinese medicine of medicine:
(1) get that the Spica Prunellae decontamination dries or a heatable brick bed done, pulverizing is that 60 purpose coarser powder are standby.
(2) get that the Herba Scutellariae Barbatae decontamination dries or a heatable brick bed done, pulverizing is that 60 purpose coarser powder are standby.
(3) getting secondary Flos Lonicerae solarization dry grinding is that 60 purpose coarser powder are standby.
(4) get the Herba Violae herb, decontamination is cleaned and to be dried or a heatable brick bed done, and pulverizing is that 60 purpose coarser powder are standby.
(5) get the Herba Taraxaci decontamination, clean, dry or a heatable brick bed done, pulverizing is that 60 purpose coarser powder are standby.
(6) get the senior flour mill of cornu saigae tatariace powder, pulverizing is that 160 purpose smalls are standby.
(7) the Cornu Bubali decontamination that Guangdong, Yunnan are produced, pulverizing with senior flour mill is that 160 purpose smalls are standby.
(8) the Radix Curcumae decontamination is cleaned section, put in the drying baker bake out temperature and be advisable with 80 ℃, pulverizing is that 60 purpose coarser powder are standby again.
(9) the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) eupolyphaga is put allowed its foreign material in the abdomen that spue that drink water in the clear water, return and change water again, with water degree of being clearly, the reuse boiled water scalds eupolyphaga dead, and drying or dry and pulverizing is that 60 purpose coarser powder are standby.
(10) getting that proper morphism perfume (or spice) grinds is that 160 purpose smalls are standby.
(11) getting the pulverizing of blood amber decontamination is that 160 purpose smalls are standby.
(12) get clean Pollen Tyjphae, pulverizing is that 160 purpose smalls are standby.
(13) Semen Persicae is put in the water purification and to be soaked 48 hours, take the photograph Clausena lansium (Lour.) Skeels, dry to put in the pot and use the slow fire parching to brown, stone roller is that the thin mud of 160 orders is standby again.
(14) get Stigma Croci and dry that to pulverize be that 160 purpose smalls are standby.
(15) Radix Notoginseng is put water purification and soak into, oven dry in the drying baker is put in section, and temperature is advisable with 80 ℃, and pulverizing is that 160 purpose smalls are standby again.
(16) the ground taro is cleaned section, put in the drying baker bake out temperature and be advisable with 80 ℃, put in the pot parch to black with high heat again, pulverizing is that 60 purpose coarser powder are standby.
(17) get it filled and use Borax, pulverizing is that 160 purpose smalls are standby.
(18) it is standby to get edible nitric acid first.
(19) Scorpio being dried pulverizing is that 60 purpose coarser powder are standby.
(20) get Bombyx Batryticatus and dry decontamination, pulverizing is that 60 purpose coarser powder are standby.
(21) the Herba Siegesbeckiae root being cleaned, dry, pulverized is that 60 purpose coarser powder are standby.
(22) Radix Platycodonis being cleaned, cut into slices, pulverized is that 60 purpose coarser powder are standby.
(23) get the system Rhizoma Pinelliae, to dry, pulverize be that 60 purpose coarser powder are standby.
(24) will draw together the stone roller that withers entirely is that 60 order mud shapes are standby.
(25) Radix Glycyrrhizae is cleaned chopping, dry or a heatable brick bed dry grinding is that 60 purpose coarser powder are standby.
(26) Mel is poured in the pot, with slow fire endure the number roll, the degree of being with the foaming, decontamination floats foam, Mel per jin get pure close 8 liang standby.
(27) 6 kilograms of the cornu saigae tatariace powders that will process the process of preparing Chinese medicine, crushes, 10 kilograms of Cornu Bubali powders, 1 kilogram of Moschus, 6 kilograms in blood amber powder, 6 kilograms in Pollen Tyjphae powder, 6 kilograms of Semen Persicae mud, 6 kilograms of safranine pollen, 6 kilograms of Radix Notoginseng powder, 10 kilograms in medicinal borax powder, edible nitric acid first mixes standby for 10 kilograms.
(28) medicated powder that will process the process of preparing Chinese medicine, crushes, 20 kilograms of Spica Prunellaes, 10 kilograms of Herba Scutellariae Barbataes, 9 kilograms of Flos Loniceraes, 10 kilograms of Herba Violaes, 20 kilograms of Herba Taraxacis, 8 kilograms of Radix Curcumaes, 4 kilograms of eupolyphaga, 10 kilograms of ground taro charcoals, 6 kilograms of Scorpios, 2 kilograms of Bombyx Batryticatus, 12 jin of Herba Siegesbeckiae, 4 kilograms of Radix Platycodoniss, 4 kilograms of Rhizoma Pinelliae, 10 kilograms of full Fructus Trichosanthis, 4 kilograms in Radix Glycyrrhizae mix standby.
By medicine processing, the process of preparing Chinese medicine, change pharmaceutical properties, improve pharmaceutical purity, medicament curative effect enhancement, the single processing of medical material is for the effective ingredient of damage medicine not, reduce survival dose, quicken pharmaceutical efficacy, obtain the purpose of oral liquid by herbal medicine immersion retort preparation, be for medicine is contacted with air, avoid bacterial infection, meet health medicine required standard, the purpose of this invention is to provide a kind of antitumor oral liquid and production method thereof for the treatment of the respiratory system cancer.
General treatment for cancer is used operation, radiotherapy, chemotherapy more both at home and abroad at present, it is big to exist side effect, kill and wound human leukocytes, reduce immunity, bigger to physical effects, life span is short, easily recurrence, the cancer that operation only is adapted to early, do not spread, shift mid-term does not still have the Chinese medicine oral liquid for lung cancer that the direct killing cancerous cell is treated cancer at present.
Embodiment:
(1) will process, concoct, crush 4 kilograms of 8 kilograms of 20 kilograms of 10 kilograms of 9 kilograms of 10 kilograms of 20 kilograms of Spica Prunellaes, Herba Scutellariae Barbataes, Flos Loniceraes, Herba Violaes, Herba Taraxacis, Radix Curcumaes, eupolyphaga having mixed, 10 kilograms of taro charcoals, 6 kilograms of Scorpios, 2 kilograms of Bombyx Batryticatus, 12 kilograms of Herba Siegesbeckiae, 4 kilograms of Radix Platycodoniss, 4 kilograms of Rhizoma Pinelliae, 10 kilograms of full Fructus Trichosanthis, 4 kilograms in Radix Glycyrrhizae, add in the retort.
(2) open retort dosing hole, the medicine that mixes is added in the retort (1).And, add the cold water of 7 times in medicated powder, (5) from water injection hole.
(3) start agitator medicine is evenly stirred, and soak 96 hours (when soak hot day extract to prevent that medicine is rotten with air in the retort) every day 3 times in immersion, each 5-10 minute, start agitator and stir, medicine is evenly soaked, (8,9).
(4) drug immersion good after, open three-way valve, add heat steam and boil 100 ℃, stopped the supple of gas or steam (7) in 40 minutes.
(5) open and put the medicine valve, add 80 order drainage screens, (13).Start vacuum pump and add a jar interior suitably pressure, the medicinal residues inner liquid medicine is extracted only, medicinal liquid is imported in the explosive box (16).
(6) with second herbal medicine immersion retort sterilization, in bleeder valve, change the sealing of 140 order drainage screens, (13).Use negative pressure, filter (6) carrying out the second time in the first tank storage medicine-chest medicinal liquid suction tank.
(7) filtering second jar of good medicinal liquid, suck in the 3rd jar with negative pressure, add cornu saigae tatariace powder 3%, Cornu Bubali powder 3%, proper morphism perfume (or spice) 1%, blood amber 3%, Pollen Tyjphae 3%, Semen Persicae 3%, Stigma Croci 3%, Radix Notoginseng powder 3%, medicinal borax 5%, edible nitric acid first 5% that pulverizing is 160 order smalls again, start agitator, medicine is stirred well, soaked 24 hours, in immersion, stirred 3 times in per 12 hours, each 5-10 minute, (8,9).
(8) with soaked medicinal liquid, the furnacing honey of adding 10% starts agitator and stirs well (8,9).Open the heat steam three-way valve and be heated to 60 ℃, (7).Close the heat steam valve; Input cold water or cold air cool completely medicine, preserve about zero degree standby, (7).Promptly become Chinese medicine oral liquid for lung cancer semi-finished product.
(9) at last the semi-finished product medicine is passed through pipeline, quantitatively send into automatic bottling, sealing production line, in the high temp glass bottle of every the 50cc that packs into.
(10) medicine bottle that will seal mouthful is emitted on shockproofly with 10 dresses, in the transparent plastic box, the box front cover is with gold stamping, paints the pattern, lot number, trade mark of tcm characteristic etc.Again that every case is box-packed with 30, be emitted in shockproof, waterproof, the anti-metal box of damaging by worms, and paint historical pattern that Chinese medicine develops etc., becoming the Chinese medicine oral liquid for lung cancer is anticancer finished medicines such as digestive system, cryopreservation is standby.
Major advantage of the present invention is, treat the multiple cancer of early, middle and late phase respiratory system of various ages, different obvious curative effects is all arranged, for early-stage cancer, healing in general about three months, healing about healing, five months late periods about four months mid-terms, 13-15 at most survives, 3-6 at least, the The average survival time rate has reached more than 7.3 years, good from puzzled card shape after healing, it is normal to work, live, and the X-ray sheet shows foci disappearance, this medicine is better than methods such as general at present operation, radiotherapy, chemotherapy both at home and abroad, and the The average survival time rate improves nearly one times.Medicinal having no side effect do not killed and wounded leukocyte, be worth cheap, no Drug resistance, safe and reliable, evident in efficacy, need not operation, radiotherapy, chemotherapy and other chemical drugs can be cured, and are domestic and international at present rare, have the desirable anticancer Chinese Traditional Medicines of tcm characteristic.
Description of drawings:
Accompanying drawing is a medicine production Processes and apparatus sketch map of the present invention, and (1) is the dosing hole, and (2) annotate the hole of calming the anger, (3) pressure vacuum gauge, (4) thermometer hole, (5) water injection hole, (6) evacuation hole, (7) heating steam hole and three-way valve, (8) reduction box, (9) agitator, (10) thermometer, (11) are given vent to anger and are chewed, (12) put the medicine valve, (13) drainage screen, (14) first medicine liquid outlets, (15) second medicine liquid outlets, (16) explosive box, (17) medicinal liquid metering degree.

Claims (28)

1, a kind of Chinese medicine oral liquid for lung cancer and production method thereof.It is characterized in that; This medicine by Spica Prunellae 10%, Herba Scutellariae Barbatae 5%, Flos Lonicerae 4%, Herba Violae 5%, Herba Taraxaci 10%, antelope half powder 3%, Cornu Bubali powder 5%, Radix Notoginseng powder 3%, Moschus 1%, blood amber 3%, Radix Curcumae 4%, eupolyphaga 2%, Pollen Tyjphae 3%, Semen Persicae 3%, Stigma Croci 3%, taro charcoal 5%, medicinal borax 5%, edible nitric acid first 5%, Scorpio 3%, Bombyx Batryticatus 1%, Herba Siegesbeckiae 6%, Radix Platycodonis 2%, clear half again 2%, full Fructus Trichosanthis 5%, Radix Glycyrrhizae 2%.To drug screening, cut into slices, dry, oven dry, parching to brown, roasting, parch to black, pulverizing, porphyrize, pulverize, soak, heat, filter, mix, be Chinese medicine oral liquid for lung cancer semi-finished product.
2, according to claim 1, feature of the present invention is; Spica Prunellae cleaned, shreds, dries or put in a heatable brick bed stove room a heatable brick bed and do, pulverizing is that 60 purpose coarser powder are standby.
3, according to claim 1, feature of the present invention is; Herba Scutellariae Barbatae is cleaned, shreds, dries or a heatable brick bed dry grinding is that 60 purpose coarser powder are standby.
4, according to claim 1, feature of the present invention is; With Flos Lonicerae, dry or a heatable brick bed dry grinding is that 60 purpose coarser powder are standby.
5, according to claim 1.Feature of the present invention is; Herba Violae is cleaned, shreds, dries or a heatable brick bed dry grinding is that 60 purpose coarser powder are standby.
6, according to claim 1, spy of the present invention is; Dandelion is cleaned, dried or a heatable brick bed dry grinding is that 60 purpose coarser powder are standby.
7, according to claim 1, feature of the present invention is; It is that 160 purpose smalls are standby that cornu saigae tatariace powder is pulverized again.
8, according to claim 1, feature of the present invention is; Cornu Bubali with Yunnan, Guangdong product.Pulverizing is that 160 purpose smalls are standby.
9, according to claim 1, feature of the present invention is; It is standby to get proper morphism perfume (or spice).
10, according to claim 1, feature of the present invention is; Radix Curcumae is cleaned, cuts into slices, put the interior bake out temperature of drying baker and be advisable with 80 ℃, pulverizing is that 60 purpose coarser powder are standby again.
11, according to claim 1, feature of the present invention is; The eupolyphaga of will living removes the internal organs foreign material, scalds that extremely to dry or dry, pulverize be that 60 purpose coarser powder are standby.
12, according to claim 1, feature of the present invention is; With clean blood amber, pulverizing is that 160 purpose smalls are standby.
13, according to claim 1, feature of the present invention is: will give birth to BOHUANG, pulverizing is that 160 order smalls are standby.
14, according to claim 1, feature of the present invention is: Semen Persicae is cooled in the water to soak took the photograph Clausena lansium (Lour.) Skeels in 48 hours, after getting pink white nucleus and drying, put a pot interior parching to brown, stone roller is that the thin mud of 160 purposes is standby.
15, according to claim 1, feature of the present invention is: get Stigma Croci and dry, pulverizing is that 160 purpose smalls are standby.
16, according to claim 1, feature of the present invention is: soak into, cut into slices, put in the drying baker and dry in Radix Notoginseng is discharged water, temperature is advisable with 80 ℃, and pulverizing is that 160 purpose smalls are standby again.
17, according to claim, feature of the present invention is: the ground taro is cleaned, and section is dried and is put in the pot parch to black with high heat, and pulverizing is that 60 order coarser powder are standby.
18, according to claim 1, feature of the present invention is: get it filled and use Borax, pulverizing is that 160 order smalls are equipped with.
19, according to claim 1, feature of the present invention is: it is standby to get edible nitric acid first.
20, according to claim 1, feature of the present invention is: it is that 60 purpose coarser powder are standby that Scorpio is dried pulverizing.
21, require describedly according to right 1, feature of the present invention is: get Bombyx Batryticatus and dry, it is that 60 order coarser powder are standby that decontamination is pulverized.
22, according to claim 1, feature of the present invention is: Herba Siegesbeckiae is shredded, cleans, dries, and pulverizing is that 60 purpose coarser powder are standby.
23, according to claim 1, feature of the present invention is: with Radix Platycodonis clean, section puts in the drying baker bake out temperature and is advisable with 80 ℃, pulverizing is that 60 purpose coarser powder are standby.
24, according to claim 1, feature of the present invention is: get the Rhizoma Pinelliae of concocting, shining dry grinding is that 60 purpose coarser powder are standby.
25, according to claim 1, feature of the present invention is: will draw together entirely withers grinds is that 60 purpose mud shapes are standby.
26, according to claim 1, feature of the present invention is: Radix Glycyrrhizae is cleaned, soaked into, it is that 60 purpose coarser powder are standby that dry grinding is shone in chopping.
27, according to claim 1, feature of the present invention is: Mel is poured in the pot endured with the slow fire refining, see aeration degree of being, it is standby to remove the floating foam of impurity.
28, according to claim 1, feature of the present invention is: will process the process of preparing Chinese medicine, the Spica Prunellae 10% that crushes, Herba Scutellariae Barbatae 5%, Flos Lonicerae 4%, Herba Violae 5%, Herba Taraxaci 10%, Radix Curcumae 4%, eupolyphaga 2%, ground taro charcoal 5%, Scorpio 3%, Bombyx Batryticatus 1%, Herba Siegesbeckiae 6%, Radix Platycodonis 2%, the Rhizoma Pinelliae 2%, full Fructus Trichosanthis 5%, Radix Glycyrrhizae 2%, coarser powder mixes to mix all pours the cold water that adds 7 times in Chinese medicine in the herbal medicine immersion retort into, soak 96 hours (soak summer air in the jar to be extracted out and prevent that medicine is rotten) every day 3 times in immersion, started agitator medicated powder is evenly soaked in each 5-10 minute.Soak good back adding vapours and boil 100 ℃, stopped the supple of gas or steam in 40 minutes, open the tapping valve and add that 80 order drainage screens carry out the first time and filter, the medicinal liquid that filters out is put into reserving liquid tank, then with second retort, clean, sterilization, with in the medicinal liquid suction tank, it is for the second time overanxious that 140 orders are carried out in pressurization with negative pressure.Again the explosive box inner liquid medicine is sucked in the 3rd jar with negative pressure, in retort, add processing is concocted, pulverizing is 160 order smalls cornu saigae tatariace powder 3%, Cornu Bubali 5%, Moschus 1%, blood amber 3%, living BOHUANG 3%, Semen Persicae 3%, Stigma Croci 3%, Radix Notoginseng 3%, medicinal borax 5%, edible nitric acid first 5% again, stir well and soak after 24 hours, heat steam is heated to 60 ℃, add 10% Mel that cooks again and stir well, preserve about zero degree, be Chinese medicine oral liquid for lung cancer semi-finished product.At last with the semi-finished product medicinal liquid, send into by pipeline, automatic powder charge, sealing production line, reinstall in the high temp glass bottle of every 50CC and seal, and with 10 dresses, be emitted in the shockproof transparent plastic box, at last with every case 30 boxes, pack in shockproof, waterproof, the anti-metal box of damaging by worms, become " Chinese medicine oral liquid for lung cancer " finished medicines.
CN 93100721 1993-01-07 1993-01-07 A kind of Chinese medicine oral liquid for lung cancer and production method thereof Pending CN1081889A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 93100721 CN1081889A (en) 1993-01-07 1993-01-07 A kind of Chinese medicine oral liquid for lung cancer and production method thereof

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Application Number Priority Date Filing Date Title
CN 93100721 CN1081889A (en) 1993-01-07 1993-01-07 A kind of Chinese medicine oral liquid for lung cancer and production method thereof

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CN1081889A true CN1081889A (en) 1994-02-16

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CN 93100721 Pending CN1081889A (en) 1993-01-07 1993-01-07 A kind of Chinese medicine oral liquid for lung cancer and production method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1052412C (en) * 1994-08-09 2000-05-17 马洪万 Cancer therapy injection
CN1057469C (en) * 1998-11-27 2000-10-18 高淑萍 Anti-lung cancer medicine
CN1060657C (en) * 1995-07-04 2001-01-17 上海华联制药公司 Nourishing medicine for preventing and curing toxic and side effect after tumor radiotherapy and chemotherapy and preparation method
CN101623097A (en) * 2009-08-05 2010-01-13 周长运 Eupolyphaga sinensis fine powder and manufacturing method thereof
CN107537663A (en) * 2017-10-20 2018-01-05 芜湖杨燕制药有限公司 A kind of pulverizing medicinal materials technique of traditional Chinese medicine

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1052412C (en) * 1994-08-09 2000-05-17 马洪万 Cancer therapy injection
CN1060657C (en) * 1995-07-04 2001-01-17 上海华联制药公司 Nourishing medicine for preventing and curing toxic and side effect after tumor radiotherapy and chemotherapy and preparation method
CN1057469C (en) * 1998-11-27 2000-10-18 高淑萍 Anti-lung cancer medicine
CN101623097A (en) * 2009-08-05 2010-01-13 周长运 Eupolyphaga sinensis fine powder and manufacturing method thereof
CN107537663A (en) * 2017-10-20 2018-01-05 芜湖杨燕制药有限公司 A kind of pulverizing medicinal materials technique of traditional Chinese medicine
CN107537663B (en) * 2017-10-20 2019-07-19 芜湖杨燕制药有限公司 A kind of pulverizing medicinal materials technique of traditional Chinese medicine

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