CN115212038B - Preparation method of hydrogel medical dressing for promoting wound healing - Google Patents
Preparation method of hydrogel medical dressing for promoting wound healing Download PDFInfo
- Publication number
- CN115212038B CN115212038B CN202210773082.8A CN202210773082A CN115212038B CN 115212038 B CN115212038 B CN 115212038B CN 202210773082 A CN202210773082 A CN 202210773082A CN 115212038 B CN115212038 B CN 115212038B
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- fixedly connected
- sliding
- rod
- plate
- hydrogel medical
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- 239000000017 hydrogel Substances 0.000 title claims abstract description 52
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 230000029663 wound healing Effects 0.000 title claims abstract description 12
- 230000001737 promoting effect Effects 0.000 title claims abstract description 11
- 238000001514 detection method Methods 0.000 claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 13
- 239000008280 blood Substances 0.000 claims abstract description 10
- 210000004369 blood Anatomy 0.000 claims abstract description 10
- 238000005070 sampling Methods 0.000 claims abstract description 9
- 239000000463 material Substances 0.000 claims abstract description 8
- 210000003491 skin Anatomy 0.000 claims abstract description 6
- 210000002615 epidermis Anatomy 0.000 claims abstract description 4
- 238000006748 scratching Methods 0.000 claims abstract description 4
- 230000002393 scratching effect Effects 0.000 claims abstract description 4
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 238000003466 welding Methods 0.000 claims description 5
- 238000001125 extrusion Methods 0.000 claims description 2
- 238000007689 inspection Methods 0.000 abstract description 5
- 235000015277 pork Nutrition 0.000 description 7
- 239000000499 gel Substances 0.000 description 5
- 230000002457 bidirectional effect Effects 0.000 description 3
- 230000002439 hemostatic effect Effects 0.000 description 3
- 238000010030 laminating Methods 0.000 description 3
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 238000005299 abrasion Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000009881 electrostatic interaction Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
- A61F13/0213—Adhesive bandages or dressings with fluid retention members the fluid retention member being a layer of hydrocolloid, gel forming material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
The invention relates to the field of hydrogel medical dressings, in particular to a preparation method of a hydrogel medical dressing for promoting wound healing. The whole quality can be conveniently improved, so that the hydrogel medical dressing produced by sampling inspection can be carried out. A method of preparing a hydrogel medical dressing for promoting wound healing, the method comprising the steps of: step one: randomly selecting one of hydrogel medical auxiliary materials produced in batches by manpower for sampling detection; step two: clamping and unfolding the produced hydrogel medical dressing from four corners by using a preparation device; step three: clamping and fixing fresh pig blocks by using a preparation device, and scratching the epidermis to exude blood; step four: and (3) attaching the developed hydrogel medical auxiliary material to the position of the skin exudation blood of the pig block, and observing.
Description
Technical Field
The invention relates to the field of hydrogel medical dressings, in particular to a preparation method of a hydrogel medical dressing for promoting wound healing.
Background
Hydrogels are classified into physical gels and chemical gels according to the network bonding of hydrogels, the physical gels are formed by physical forces such as electrostatic interactions, hydrogen bonds, chain entanglement, etc., the gels are non-permanent and can be converted into solutions by heating the gels, wherein the prior art, for example, application number 201810820297.4, is a method for preparing supramolecular hydrogels containing silver nanoparticles, which can solve the technical problems of in-situ growth of nano-silver in the supramolecular hydrogels in the prior art, but is not convenient to improve the overall quality for sampling examination, and the medical dressings of hydrogels produced by the prior art.
Disclosure of Invention
The invention aims to provide a preparation method of a hydrogel medical dressing for promoting wound healing, which can facilitate the improvement of the overall quality so as to carry out sampling inspection on the produced hydrogel medical dressing.
The aim of the invention is achieved by the following technical scheme: a method of preparing a hydrogel medical dressing for promoting wound healing, the method comprising the steps of:
step one: randomly selecting one of hydrogel medical auxiliary materials produced in batches by manpower for sampling detection;
step two: clamping and unfolding the produced hydrogel medical dressing from four corners by using a preparation device;
step three: clamping and fixing fresh pig blocks by using a preparation device, and scratching the epidermis to exude blood;
step four: and (3) attaching the developed hydrogel medical auxiliary material to the position of the skin exudation blood of the pig block, and observing.
Preferably, the preparation facilities includes four expansion shelves that set up along the circumferencial direction, and the top of every expansion shelf all rotates and is connected with a end slide, and the equal fixedly connected with slide bar in top of every end slide, the equal fixedly connected with grip block I in top of every slide bar, all relies on inclined rod sliding connection to have a grip block II on every grip block I.
Preferably, each inclined rod is inserted and slid on the corresponding clamping plate I in an inclined direction.
Preferably, a plurality of grooves for improving friction force are arranged between the opposite surfaces of each clamping plate I and each corresponding clamping plate II.
Drawings
The invention will be described in further detail with reference to the accompanying drawings and detailed description.
FIG. 1 is a schematic flow diagram of a method of preparing a hydrogel medical dressing for promoting wound healing in accordance with the present invention;
FIG. 2 is a schematic view of the structure of the unfolding frame of the present invention;
FIG. 3 is an enlarged schematic view of the partial structure of FIG. 2 in accordance with the present invention;
FIG. 4 is a schematic diagram of the structure of the detection frame of the present invention;
FIG. 5 is an enlarged schematic view of the partial structure of FIG. 4 in accordance with the present invention;
FIG. 6 is a schematic view of the push seat of the present invention;
FIG. 7 is a schematic view of the jacking plate structure of the present invention;
FIG. 8 is a schematic view of the structure of a communication pipe according to the present invention;
fig. 9 and 10 are schematic views of the overall structure of the present invention;
in the figure: an expanding frame 101; a slide bar 102; a bottom slider 103; a top slide 104; clamping plate I105; defining a block 106; a link lever 107; clamping plate II 108; a diagonal lever 109; electric push rod I110; a detection rack 201; a four-way plate 202; an electric push rod II 203; a push seat 204; a lifting lever 205; a concave plate 206; a right angle seat 207; an elongated aperture 208; a jack-up plate 301; a side plate 302; a slide bar 303; a bi-directional board 304; electric putter III 305; a communicating tube 401; a syringe 402; pushing the rod 403.
Detailed Description
A method of preparing a hydrogel medical dressing for promoting wound healing, the method comprising the steps of:
step one: randomly selecting one of hydrogel medical auxiliary materials produced in batches by manpower for sampling detection;
step two: clamping and unfolding the produced hydrogel medical dressing from four corners by using a preparation device;
step three: clamping and fixing fresh pig blocks by using a preparation device, and scratching the epidermis to exude blood;
step four: and (3) attaching the developed hydrogel medical auxiliary material to the position of the skin exudation blood of the pig block, and observing.
This part works according to what is expressed in fig. 2 and 3: the preparation facilities includes four expansion frame 101, four expansion frame 101 evenly set up along the circumferencial direction, the end slide 103 that corresponds with expansion frame 101 also is equipped with four, and the bottom of every end slide 103 all rotates the top of connecting at every end slide 103 that corresponds, the top of every end slide 103 all is through a welded connection sliding rod 102, the top of every sliding rod 102 all is through a bolt fixedly connected with grip block I105, all sliding connection has an slant pole 109 on every grip block I105, all fixedly connected with grip block II 108 on every slant pole 109.
To explain further, in the preparation production of the hydrogel medical dressing that promotes wound healing, in order to be convenient for improve whole quality and thereby carry out the sample inspection product quality, when using, at first laminate the four corners department of hydrogel medical dressing through the grip block I105 on four expansion brackets 101 that set up along the circumferencial direction to laminate the centre gripping by every grip block II 108 of slant sliding connection on every grip block I105 with the four corners department of the hydrogel medical dressing that samples inspected, the slant pole 109 of slant sliding on every grip block I105 is convenient for grip block II 108 to rely on this inclined angle to carry out the slip laminating to grip block I105.
The rear side of every grip block I105 all fixedly connected with prescribes a limit to frame 106, all sliding connection has the lower extreme of a gangbar 107 on every prescribing a limit to the frame 106, and the upper end of every gangbar 107 all rotates the connection at every the rear end of grip block II 108, the bottom of every gangbar 107 all rotates the expansion end that is connected with an electric putter I110 respectively, the stiff end of every electric putter I110 is fixed connection in the left side of every grip block I105 respectively.
This part works according to what is expressed in fig. 2 and 3: the rear side plane of each clamping plate I105 is fixedly connected with a limiting frame 106 through welding, the lower end of each linkage rod 107 is slidably connected in each limiting frame 106, the upper end of each linkage rod 107 is rotatably connected to the rear end of each clamping plate II 108, four electric push rods I110 are correspondingly arranged, movable ends of the four electric push rods I110 are rotatably connected to the bottom of each linkage rod 107 through flanges, and fixed ends of each electric push rod I110 are fixedly connected to the left side of each clamping plate I105 through flanges.
To further explain, when every grip block I105 and grip block II 108 are close to each other and grasp hydrogel medical dressing, drive every corresponding electric putter I110 and drive the bottom of the gangbar 107 on the movable end and slide on every corresponding limiting frame 106, make every gangbar 107 upper end rotate the grip block II 108 of connection rely on every slant pole 109 to slide down at this moment, and then expand the centre gripping to hydrogel medical dressing, the follow-up experimenter of being convenient for inspects its product quality, and every slant pole 109 slope sets up and is in order to improve the frictional force of grip block I105 and grip block II 108 to hydrogel medical dressing when pressing down, be favorable to further forbidden to solid the frictional force of grasping hydrogel medical dressing.
The preparation device further comprises a detection frame 201 and four-way plates 202 fixedly connected to four corners of the top of the detection frame 201, a strip hole 208 for sliding each sliding rod 102 is formed in each four-way plate 202, a top sliding seat 104 is fixedly connected to the middle of each sliding rod 102, and each top sliding seat 104 is respectively attached to the top of each corresponding four-way plate 202 in a sliding mode.
The bottoms of the front and rear ends of each top slider 104 are arc-shaped.
The upper surface of each four-way plate 202 is a slope inclined toward the middle of each four-way plate 202.
This part is according to the working procedure expressed in figures 4, 5, 6 and 9, 10: four-way board 202 is equipped with four along the circumferencial direction, four-way boards 202 are respectively through welded fastening connection in detection frame 201 top four corners department, all have a rectangular hole 208 through milling machine processing on every four-way board 202, all sliding connection has a slide bar 102 in every rectangular hole 208, the middle part of every slide bar 102 is all through welded fastening connection with a top slide 104, the slide bar 102 laminates the slip through corresponding top slide 104 laminating at the upper surface of corresponding four-way board 202 when the interior slip of rectangular hole 208, the front and back both ends of every top slide 104 bottom do benefit to top slide 104 laminating and slide at the upper surface of every four-way board 202 through the arc that forms of polishing, see fig. 6 in detail, the upper surface of every four-way board 202 is the inclined plane to the middle part.
To further explain, when the hydrogel medical dressing is clamped by each clamping plate i 105 and each clamping plate ii 108, in order to facilitate the unfolding of the clamped hydrogel medical dressing, each sliding rod 102 is driven by each unfolding frame 101 located at the bottom of the clamping plate i 105 to slide on the elongated hole 208 on each corresponding four-way plate 202, when the sliding rod 102 slides, each top sliding seat 104 located in the middle of the sliding rod 102 is attached to the upper surface of the four-way plate 202 to slide, and the bottom of each top sliding seat 104 has an arc-shaped position to facilitate the sliding of each top sliding seat 104, and to facilitate the further improvement of the smoothness of the overall movement, so that when each top sliding seat 104 slides, the corresponding four-way plate 202 is an inclined plane in side view, which facilitates the improvement of the sliding smoothness of the device, and further expands the clamped medical dressing with different specifications, which is beneficial to the observation of whether the surface has abrasion or not by hydrogel laboratory staff, and the extensibility of the corresponding hydrogel dressing for sampling inspection.
The bottom fixedly connected with electric putter II 203 at the middle part of detection frame 201's stiff end, electric putter II 203's movable end fixedly connected with promotes seat 204, promotes the four corners department of seat 204 and rotates with the bottom of four expansion brackets 101 respectively and be connected.
The middle part fixedly connected with lifter 205 of promotion seat 204, lifter 205 sliding connection is at the middle part of detecting the frame 201 upside, and the top fixedly connected with concave board 206 of lifter 205, the left and right sides both ends of concave board 206 are fixedly connected with right angle seat 207 respectively.
This part is according to the working procedure expressed in figures 4, 5, 6 and 9, 10: the fixed end of the electric push rod II 203 is fixedly connected to the bottom of the middle part of the detection frame 201 through a flange, the movable end of the electric push rod II 203 is fixedly connected with a pushing seat 204 through a flange, and the bottom ends of the four unfolding frames 101 are respectively and rotatably connected to four corners of the pushing seat 204;
the middle part of pushing seat 204 is through bolt fixedly connected with lifter 205, and the middle part sliding connection of detection frame 201 upside has lifter 205, and the top of lifter 205 is through bolt fixedly connected with concave board 206, and the both ends are respectively through welded fixedly connected with right angle seat 207 about concave board 206.
To further explain, when each unfolding frame 101 drives the hydrogel medical dressing clamped at the upper part to unfold, the electric push rod II 203 is driven to drive the pushing seat 204 located at the movable end of the electric push rod II 203 to lift, at this time, the unfolding frame 101 rotationally connected in the circumferential direction of the pushing seat 204 is further pulled downwards or pushed upwards, and then when the movable end of the electric push rod II 203 lifts up, the unfolding frame 101 drives the clamped hydrogel medical dressing to unfold, the concave plate 206 located at the upper end of the pushing seat 204 subsequently jacks up fresh pork with pigskin, at this time, the hydrogel medical dressing is conveniently attached to the pigskin of the pork, and the hemostatic effect of the hydrogel medical dressing on the bleeding position when the skin of the attached pork position is conveniently detected.
This part works according to what is expressed in figures 7, 9 and 10: the front end and the rear end of the concave plate 206 are respectively connected with a sliding rod 303 in a sliding manner, the top ends of the two sliding rods 303 are respectively connected with the front end and the rear end of the jacking plate 301 through welding, the bottom of each sliding rod 303 is fixedly connected with a bidirectional plate 304 through welding, the outer sides of the two bidirectional plates 304 are respectively connected with the movable ends of the two electric pushing rods III 305 through flanges, the fixed ends of the two electric pushing rods III 305 are fixedly connected with the two right-angle seats 207 through flanges, and the middle parts of the right ends of the jacking plates 301 are integrally provided with side plates 302.
When the pork-shaped plate 206 is used, the pork-shaped plate is further attached to the hydrogel medical dressing covered on the pork, the jacking plate 301 on the concave plate 206 is further selected to be placed, at this time, the two electric pushing rods III 305 are synchronously driven, the two bidirectional plates 304 on the movable end of the electric pushing rods III 305 are driven to push the sliding rods 303 to push the pork on the jacking plate 301 upwards to be further attached to the unfolded hydrogel medical dressing, and the stretching degree and the breakage degree of the hydrogel medical dressing are further detected conveniently.
This part works according to what is expressed in figures 8, 9 and 10: the middle part of jack-up board 301 right-hand member passes through the right side of bolt fixedly connected with communicating pipe 401, and the right side of communicating pipe 401 passes through bolt fastening and communicates there is injection tube 402, and injection tube 402 passes through bolt fastening to be connected on curb plate 302, and injection tube 402 sliding connection has the push rod 403 of extrusion inside air.
To further explain, in order to facilitate the detection of the hemostatic performance of the hydrogel medical dressing, the left sharp portion of the communicating tube 401 is inserted into the pork through the communicating tube 401, and the blood is discharged from the syringe 402 communicated with the communicating tube 401 at the scraping position of the pork skin, and the blood of the syringe 402 is discharged by pressing the push rod 403, so that the hemostatic performance of the hydrogel medical dressing for sampling inspection can be observed manually, and various performances of the hydrogel medical dressing for promoting wound healing can be detected conveniently.
Claims (2)
1. A method of preparing a hydrogel medical dressing for promoting wound healing, the method comprising the steps of:
step one: randomly selecting one of hydrogel medical auxiliary materials produced in batches by manpower for sampling detection;
step two: clamping and unfolding the produced hydrogel medical dressing from four corners by using a preparation device;
step three: clamping and fixing fresh pig blocks by using a preparation device, and scratching the epidermis to exude blood;
step four: attaching the developed hydrogel medical auxiliary material to the position of the skin of the pig block where blood seeps out, and observing;
the preparation device comprises four unfolding frames (101) arranged along the circumferential direction, wherein the top end of each unfolding frame (101) is rotatably connected with a bottom sliding seat (103), the top of each bottom sliding seat (103) is fixedly connected with a sliding rod (102), the top end of each sliding rod (102) is fixedly connected with a clamping plate I (105), and each clamping plate I (105) is slidably connected with a clamping plate II (108) by means of an inclined rod (109);
each inclined rod (109) is inserted and slid on the corresponding clamping plate I (105) in an inclined direction;
a plurality of grooves for improving friction force are arranged between the opposite surfaces of each clamping plate I (105) and each corresponding clamping plate II (108);
the rear side of each clamping plate I (105) is fixedly connected with a limiting frame (106), each limiting frame (106) is connected with a linkage rod (107) in a sliding manner, the upper end of each linkage rod (107) is rotationally connected to the rear end of each clamping plate II (108), the bottom of each linkage rod (107) is rotationally connected with a movable end of an electric push rod I (110) respectively, and the fixed end of each electric push rod I (110) is fixedly connected to the left side of each clamping plate I (105) respectively;
the preparation device further comprises a detection frame (201) and four-way plates (202) fixedly connected to four corners of the top of the detection frame (201), wherein each four-way plate (202) is provided with a long strip hole (208) for sliding each sliding rod (102), the middle part of each sliding rod (102) is fixedly connected with a top sliding seat (104), and each top sliding seat (104) is respectively attached to the top of each corresponding four-way plate (202) to slide;
the bottoms of the front end and the rear end of each top sliding seat (104) are arc-shaped;
the upper side surface of each four-way plate (202) is an inclined surface inclined towards the middle part of each four-way plate (202);
the bottom of the middle part of the detection frame (201) is fixedly connected with the fixed end of an electric push rod II (203), the movable end of the electric push rod II (203) is fixedly connected with a pushing seat (204), and four corners of the pushing seat (204) are respectively connected with the bottom ends of the four unfolding frames (101) in a rotating way;
the middle part of the pushing seat (204) is fixedly connected with a lifting rod (205), the lifting rod (205) is slidably connected with the middle part of the upper side of the detection frame (201), the top of the lifting rod (205) is fixedly connected with a concave plate (206), and the left end and the right end of the concave plate (206) are respectively fixedly connected with a right-angle seat (207);
the front end and the rear end of the concave plate (206) are respectively connected with a sliding rod (303) in a sliding mode, the top ends of the two sliding rods (303) are respectively connected with the front end and the rear end of the jacking plate (301) through welding, the bottom of each sliding rod (303) is fixedly connected with a two-way plate (304) through welding, the outer sides of the two-way plates (304) are respectively connected with the movable ends of the two electric pushing rods III (305) through flanges, the fixed ends of the two electric pushing rods III (305) are fixedly connected with the two right-angle seats (207) through flanges, and the middle parts of the right ends of the jacking plates (301) are integrally provided with side plates (302).
2. The method according to claim 1, characterized in that: the middle part of jack-up board (301) right-hand member passes through the right side of bolt fixedly connected with communicating pipe (401), and the right side of communicating pipe (401) passes through bolt fastening and communicates there is injection syringe (402), and injection syringe (402) pass through bolt fastening connection on curb plate (302), and injection syringe (402) sliding connection has push rod (403) of extrusion inside air.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210773082.8A CN115212038B (en) | 2022-06-30 | 2022-06-30 | Preparation method of hydrogel medical dressing for promoting wound healing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210773082.8A CN115212038B (en) | 2022-06-30 | 2022-06-30 | Preparation method of hydrogel medical dressing for promoting wound healing |
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| Publication Number | Publication Date |
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| CN115212038A CN115212038A (en) | 2022-10-21 |
| CN115212038B true CN115212038B (en) | 2023-08-25 |
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| CN202210773082.8A Active CN115212038B (en) | 2022-06-30 | 2022-06-30 | Preparation method of hydrogel medical dressing for promoting wound healing |
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| JPH1078300A (en) * | 1996-09-04 | 1998-03-24 | Toray Ind Inc | Auxiliary material for spreading camouflage net, skeleton for spreading camouflage net and camouflage net spreading structure |
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| CN115212038A (en) | 2022-10-21 |
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