CN115165996A - Urine detection method and device - Google Patents
Urine detection method and device Download PDFInfo
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- CN115165996A CN115165996A CN202210936783.9A CN202210936783A CN115165996A CN 115165996 A CN115165996 A CN 115165996A CN 202210936783 A CN202210936783 A CN 202210936783A CN 115165996 A CN115165996 A CN 115165996A
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- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
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- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
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Abstract
The embodiment of the application discloses a urine detection method and a device; the method comprises the following steps: reacting with the tested urine through a receptor preset in the biosensor to generate an electroactive substance; when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device; when the signal processing system detects the received electric signal, calculating the substrate concentration in the tested urine based on the electric signal; judging the disease condition according to the substrate concentration according to a preset diagnosis rule; the embodiment of the application realizes simply conveniently detecting the urine in order to acquire the disease state, can acquire the detection result rapidly, and the detection result is visual and clear.
Description
Technical Field
The embodiment of the application relates to the technical field of detection, in particular to a urine detection method and device.
Background
The urine examination includes routine analysis of urine, detection of a visible component in urine (e.g., urine red blood cells, white blood cells, etc.), quantitative determination of a protein component, measurement of urease, and the like. Urine examination has important values for clinical diagnosis, judgment of curative effect and prognosis.
In the prior art, in order to detect human urine, a temperature sensor, a humidity sensor and an odor sensor are arranged at the bottom of a paper diaper, a plug socket is arranged at the upper end of the paper diaper, when signals of the temperature sensor, the humidity sensor and the odor sensor are detected to exceed limit values, the signals are sent out, a single chip microcomputer controller controls an LED display lamp to flash and alarm through a light controller according to different conditions, and the single chip microcomputer controller controls an acoustic generator to send out sound alarm through a sound controller. Although the technology realizes alarming and information transmission, the information collected by sensing is not stored and the data collected by sensing is not analyzed, so that health detection cannot be carried out at the first time.
Disclosure of Invention
The embodiment of the application provides a urine detection method and a urine detection device, which can simply and conveniently detect urine to obtain disease conditions, can rapidly obtain detection results, and are visual and clear.
In a first aspect, embodiments of the present application provide a urine detection method, including the following steps:
reacting with the tested urine through a receptor preset in the biosensor to generate an electroactive substance;
when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device;
when the signal processing system detects the received electric signal, calculating the substrate concentration in the tested urine based on the electric signal;
and judging the disease condition according to the substrate concentration according to a preset diagnosis rule.
Further, the signal processing system detects the received electrical signal and calculates a substrate concentration based on the electrical signal, comprising:
if the current value is larger, the substrate concentration is higher; the lower the current value, the lower the substrate concentration;
wherein the concentration range of the substrate concentration corresponds to the current range of the current value.
Further, the judging the disease status according to the substrate concentration according to the preset diagnosis rule comprises:
obtaining a corresponding substrate concentration type according to a receptor preset in the bioreactor;
determining whether the value of the substrate concentration meets a preset model;
when the numerical value of the substrate concentration accords with the preset model, determining that the numerical value of the substrate concentration is normal;
and when the numerical value of the substrate concentration does not accord with the preset model, determining that the numerical value of the substrate concentration is abnormal.
Further, the determining whether the value of the substrate concentration meets a preset model comprises:
according to the substrate concentration type, obtaining an expected value corresponding to the substrate concentration of the type in the preset model;
determining whether the value of the substrate concentration complies with the preset model based on a degree of deviation of the value of the substrate concentration from the corresponding expected value.
Further, when the value of the substrate concentration meets the preset model, determining that the value of the substrate concentration is normal comprises:
when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a first threshold range, determining that the numerical value of the substrate concentration is normal, and carrying out disease prevention warning;
wherein, when the value of the substrate concentration does not conform to the preset model, determining that the value of the substrate concentration is abnormal comprises:
when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a second threshold value range, determining that the numerical value of the substrate concentration is abnormal, and performing slight disease warning;
and when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a third threshold range, determining that the numerical value of the substrate concentration is abnormal, and warning serious diseases.
In a second aspect, embodiments of the present application further provide a urine detection device, including: the diaper comprises a diaper body, a signal processing system, a biosensor, a signal transmitting device and a button cell cabin; the paper diaper body comprises a base fabric, waistline parts are arranged at the upper end and the lower end of the base fabric, and an absorption core body is arranged on the base fabric; the biosensor is arranged on the absorption core body, the signal transmitting device is arranged on the base cloth, the button battery cabin is arranged on the waistline part, and the signal transmitting device is connected with the biosensor and the button battery cabin;
the biosensor is used for sending an electric signal of an electroactive substance generated by the reaction between a preset receptor and the tested urine to the signal processing system through the signal transmitting device; the signal processing system is used for detecting the received electric signal, calculating the substrate concentration in the detected urine on the basis of the electric signal, and judging the disease state according to the substrate concentration according to a preset diagnosis rule.
Further, the diaper body further comprises urine wetness display paper, and the urine wetness display paper is arranged on the absorption core body.
Further, the absorption core body comprises a non-woven fabric surface layer, a flow guide layer, a water absorption layer and a bottom film which are sequentially arranged; the urine wet display paper is arranged between the water absorption layer and the bottom film.
In a third aspect, an embodiment of the present application further provides a computer device, including: a memory and one or more processors;
the memory for storing one or more programs;
when executed by the one or more processors, cause the one or more processors to implement a urine detection method as described above.
In a fourth aspect, embodiments of the present application further provide a storage medium containing computer-executable instructions for performing a urine detection method as described above when executed by a computer processor.
According to the embodiment of the application, the receptor preset in the biosensor reacts with the tested urine to generate an electroactive substance; when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device; when the signal processing system detects the received electric signal, calculating the substrate concentration in the tested urine based on the electric signal; judging the disease condition according to the substrate concentration according to a preset diagnosis rule; the urine can be simply and conveniently detected to obtain the disease condition, the detection result can be rapidly obtained, and the detection result is visual and clear.
Drawings
FIG. 1 is a flow chart of a urine testing method provided by an embodiment of the present application;
FIG. 2 is a schematic structural diagram of a urine testing device provided in an embodiment of the present application;
FIG. 3 is a schematic view of an absorbent core structure of a urine testing device provided in accordance with an embodiment of the present application;
fig. 4 is a schematic structural diagram of a computer device according to an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, specific embodiments of the present application will be described in detail with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of and not restrictive on the broad application. It should be further noted that, for the convenience of description, only some but not all of the matters relating to the present application are shown in the drawings. Before discussing exemplary embodiments in more detail, it should be noted that some exemplary embodiments are described as processes or methods depicted as flowcharts. Although a flowchart may describe the operations (or steps) as a sequential process, many of the operations can be performed in parallel, concurrently, or simultaneously. In addition, the order of the operations may be re-arranged. The process may be terminated when its operations are completed, but may have additional steps not included in the figure. The processes may correspond to methods, functions, procedures, subroutines, and the like.
According to the urine detection method, the urine can be simply and conveniently detected to obtain the disease condition, the detection result can be rapidly obtained, and the detection result is visual and clear.
The urine detection method provided in the embodiments may be performed by a urine detection device, which may be implemented by software and/or hardware and integrated in a urine detection apparatus. The urine detection device may be a computer or the like.
Fig. 1 is a flowchart of a urine detection method according to an embodiment of the present disclosure. With reference to fig. 1 and 2, the method comprises the following steps:
In the biosensor, a receptor for a marker related to a disease of an infant is pre-stored, and an enzyme biosensor, also called an enzyme electrode, is used to selectively detect a component by converting the amount of a substance generated or consumed in a chemical reaction between urine and various bioactive enzymes into an electric signal by an electrochemical device.
Specifically, when the enzyme electrode is permeated into the tested urine, the substrate to be tested enters the enzyme layer and participates in the reaction, most of the enzyme reactions can generate or consume a substance which can be tested by the implantable electrode, when the reaction reaches a steady state, the concentration of the electroactive substance can be tested in a potential or current mode, and the output current is directly related to the concentration of the substrate.
For example, when the method is applied to detecting the content of substances such as protein, glucose and ketone bodies, bilirubin values, urobilinogen and the like, and the detection result shows that if the protein is higher than the normal amount, certain problems such as glomerulonephritis and pyelonephritis may occur in the kidney of a user; 2. if the glucose value in the urine is higher than the normal amount, the user is reflected to have diabetes; 3. if the bilirubin in urine is higher than normal amount, it will indicate abnormality of liver, such as hepatitis and jaundice.
And 120, when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device.
Specifically, the potential mode is an ion detection mode, the urobilinogen electrode detects that the urobilinogen content is higher than a normal value, a response potential for overhigh urobilinogen is generated, the current mode is an oxygen detection mode, the glucose electrode detects that the glucose content is higher than the normal value, a response current for overhigh glucose is generated, the reaction of the substrate is detected in the mode, and specifically, when the detected urine content reaches or is higher than the related content of a preset disease, the disease state suffered by the user is directly reflected.
Specifically, the higher the current value, the higher the substrate concentration; the lower the current value, the lower the substrate concentration; wherein the concentration range of the substrate concentration corresponds to the current range of the current value. Illustratively, when the current value is within a first set current range, the substrate concentration is within a first set concentration range, and when the current value is within a second set current range, the substrate concentration is within a second set concentration range; the first set current range, the first set concentration range, the second set current range and the second set concentration range can be set according to specific types of the receptor and substrate concentrations of the specific biosensor, and the examples of the application are not limited thereto.
And step 140, judging the disease state according to the substrate concentration according to a preset diagnosis rule.
Wherein, the judging the disease state according to the substrate concentration according to the preset diagnosis rule comprises the following steps: obtaining a corresponding substrate concentration type according to a receptor preset in the bioreactor; determining whether the value of the substrate concentration meets a preset model; when the numerical value of the substrate concentration accords with the preset model, determining that the numerical value of the substrate concentration is normal; and when the numerical value of the substrate concentration does not accord with the preset model, determining that the numerical value of the substrate concentration is abnormal.
Optionally, the determining whether the value of the substrate concentration meets a preset model comprises: according to the substrate concentration type, obtaining an expected value corresponding to the substrate concentration of the type in the preset model; determining whether the value of the substrate concentration complies with a preset model based on a degree of deviation of the value of the substrate concentration from a corresponding expected value.
Optionally, when the value of the substrate concentration meets the preset model, determining that the value of the substrate concentration is normal includes: when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a first threshold value range, determining that the numerical value of the substrate concentration is normal, and performing disease prevention warning;
wherein, when the value of the substrate concentration does not conform to the preset model, determining that the value of the substrate concentration is abnormal comprises: when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a second threshold value range, determining that the numerical value of the substrate concentration is abnormal, and performing slight disease warning; and when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a third threshold range, determining that the numerical value of the substrate concentration is abnormal, and warning serious diseases.
Illustratively, when the concentration of the substrate is higher than an expected value, the value of the concentration of the substrate is proved to be abnormal, a slight disease risk exists, and a signal processing system sends out a slight disease warning; if the substrate concentration is too high to exceed the expected value, serious disease risks exist, and a signal processing system sends out serious disease warnings.
On the basis of the above embodiments, fig. 2 is a schematic structural diagram of a urine detection device provided in the embodiments of the present application. Referring to fig. 2, the urine detection device provided in this embodiment specifically includes: the diaper comprises a diaper body 1, a signal processing system 5, a biosensor 3, a signal transmitting device 4 and a button cell bin 7; the paper diaper body comprises a base fabric 11, the upper end and the lower end of the base fabric are provided with waistline parts 12, and the base fabric is provided with an absorption core body 2; the biosensor is arranged on the absorption core body, the signal transmitting device is arranged on the base cloth, the button battery cabin is arranged on the waistline part, and the signal transmitting device is connected with the biosensor and the button battery cabin;
the biosensor is used for sending an electric signal of an electroactive substance generated by the reaction between a preset receptor and the tested urine to the signal processing system through the signal transmitting device; the signal processing system is used for detecting the received electric signals, calculating the substrate concentration in the detected urine on the basis of the electric signals, and judging the disease condition according to the substrate concentration according to a preset diagnosis rule.
In some embodiments, the diaper body further comprises a urine wetness indicator paper 6 disposed on the absorbent core; the substrate of the urine wet display paper contains biological enzyme which can develop the color of uric acid, urea, bilirubin, glucose, pathogenic bacteria and the like. So that the components in the urine can be visually judged.
In some embodiments, referring to fig. 3, the absorbent core comprises a nonwoven fabric surface layer 21, a flow guiding layer 22, a water absorbing layer 23 and a bottom film 24; the urine wet display paper is arranged between the water absorption layer and the bottom film.
Optionally, the basement membrane is the transparent basement membrane of PE, and the colour condition of urine wet display paper is observed directly perceivedly to the transparent basement membrane of accessible PE, and the state of urine wet display paper is observed convenient and fast to judge the composition that contains in the urine, provide the basis to disease analysis.
In some embodiments, the signal transmitting device adopts a signal transmission device with a wireless transmission function, such as bluetooth or wifi.
Reacting with the detected urine through a receptor preset in the biosensor to generate an electroactive substance; when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device; when the signal processing system detects the received electric signal, calculating the substrate concentration in the detected urine on the basis of the electric signal; judging the disease condition according to the substrate concentration according to a preset diagnosis rule; the urine detection device can simply and conveniently detect urine so as to obtain disease conditions, can quickly obtain detection results, and is visual and clear in detection results.
The urine detection device provided by the embodiment of the application can be used for executing the urine detection method provided by the embodiment, and has corresponding functions and beneficial effects.
The embodiment of the application also provides computer equipment which can be integrated with the urine detection device provided by the embodiment of the application. Fig. 4 is a schematic structural diagram of a computer device according to an embodiment of the present application. Referring to fig. 4, the computer apparatus includes: an input device 43, an output device 44, a memory 42, and one or more processors 41; the memory 42 for storing one or more programs; when executed by the one or more processors 41, the one or more programs cause the one or more processors 41 to implement the urine detection method provided in the embodiments described above. The input device 43, the output device 44, the memory 42 and the processor 41 may be connected by a bus or other means, and fig. 4 illustrates the connection by the bus as an example.
The processor 41 executes various functional applications and data processing of the device by running software programs, instructions and modules stored in the memory 41, so as to implement the urine detection method described above.
The computer device provided by the above can be used for executing the urine detection method provided by the above embodiment, and has corresponding functions and beneficial effects.
Embodiments of the present application also provide a storage medium containing computer-executable instructions, which when executed by a computer processor, are configured to perform a urine detection method, the urine detection method comprising: reacting with the tested urine through a receptor preset in the biosensor to generate an electroactive substance; when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device; when the signal processing system detects the received electric signal, calculating the substrate concentration in the tested urine based on the electric signal; and judging the disease condition according to the substrate concentration according to a preset diagnosis rule.
Storage medium-any of various types of memory devices or storage devices. The term "storage medium" is intended to include: mounting media such as CD-ROM, floppy disk, or tape devices; computer device memory or random access memory such as DRAM, DDRRAM, SRAM, EDORAM, lanbus (Rambus) RAM, etc.; non-volatile memory, such as flash memory, magnetic media (e.g., hard disk or optical storage); registers or other similar types of memory elements, etc. The storage medium may also include other types of memory or combinations thereof. In addition, the storage medium may be located in a first computer apparatus in which the program is executed, or may be located in a different second computer apparatus connected to the first computer apparatus through a network (such as the internet). The second computer device may provide program instructions to the first computer for execution. The term "storage medium" may include two or more storage media that may reside in different locations, such as in different computer devices that are connected via a network. The storage medium may store program instructions (e.g., embodied as a computer program) that are executable by one or more processors.
Of course, the storage medium provided in the embodiments of the present application contains computer-executable instructions, and the computer-executable instructions are not limited to the urine detection method described above, and may also execute related operations in the urine detection method provided in any embodiment of the present application.
The urine detection device, the storage medium, and the computer device provided in the above embodiments may perform the urine detection method provided in any embodiments of the present application, and reference may be made to the urine detection method provided in any embodiments of the present application without detailed technical details described in the above embodiments.
The foregoing is considered as illustrative of the preferred embodiments of the invention and the technical principles employed. The present application is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present application has been described in more detail with reference to the above embodiments, the present application is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present application, and the scope of the present application is determined by the scope of the claims.
Claims (10)
1. A urine testing method, comprising the steps of:
reacting with the tested urine through a receptor preset in the biosensor to generate an electroactive substance;
when the reaction reaches a steady state, measuring the current or potential of the electroactive substance, and sending an electric signal to a signal processing system through a signal transmitting device;
when the signal processing system detects the received electric signal, calculating the substrate concentration in the tested urine based on the electric signal;
and judging the disease condition according to the substrate concentration according to a preset diagnosis rule.
2. The urine testing method of claim 1, wherein said signal processing system detects said electrical signal received and calculates a substrate concentration based on said electrical signal, comprising:
if the current value is larger, the substrate concentration is higher; the lower the current value, the lower the substrate concentration;
wherein the concentration range of the substrate concentration corresponds to the current range of the current value.
3. The urine test method according to claim 1, wherein said judging the disease state based on the substrate concentration according to the preset diagnostic rule comprises:
obtaining a corresponding substrate concentration type according to a receptor preset in the bioreactor;
determining whether the value of the substrate concentration meets a preset model;
when the numerical value of the substrate concentration accords with the preset model, determining that the numerical value of the substrate concentration is normal;
and when the numerical value of the substrate concentration does not accord with the preset model, determining that the numerical value of the substrate concentration is abnormal.
4. The urine test method according to claim 3, wherein said determining whether the value of the substrate concentration meets a predetermined model comprises:
according to the substrate concentration type, obtaining an expected value corresponding to the substrate concentration of the type in the preset model;
determining whether the value of the substrate concentration complies with the preset model based on a degree of deviation of the value of the substrate concentration from the corresponding expected value.
5. The urine test method according to claim 3, wherein said determining that the value of the substrate concentration is normal when the value of the substrate concentration conforms to the preset model comprises:
when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a first threshold range, determining that the numerical value of the substrate concentration is normal, and carrying out disease prevention warning;
wherein, when the value of the substrate concentration does not conform to the preset model, determining that the value of the substrate concentration is abnormal comprises:
when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a second threshold range, determining that the numerical value of the substrate concentration is abnormal, and carrying out slight disease warning;
and when the deviation degree of the numerical value of the substrate concentration and the corresponding expected value is in a third threshold range, determining that the numerical value of the substrate concentration is abnormal, and carrying out serious disease warning.
6. A urine testing device, comprising: the diaper comprises a diaper body, a signal processing system, a biosensor, a signal transmitting device and a button cell cabin; the paper diaper body comprises a base fabric, waistline parts are arranged at the upper end and the lower end of the base fabric, and an absorption core body is arranged on the base fabric; the biosensor is arranged on the absorption core body, the signal transmitting device is arranged on the base cloth, the button battery cabin is arranged on the waistline part, and the signal transmitting device is connected with the biosensor and the button battery cabin;
the biosensor is used for sending an electric signal of an electroactive substance generated by the reaction between a preset receptor and the tested urine to the signal processing system through the signal transmitting device; the signal processing system is used for detecting the received electric signal, calculating the substrate concentration in the detected urine on the basis of the electric signal, and judging the disease condition according to the substrate concentration according to a preset diagnosis rule.
7. The urine testing device of claim 6, wherein the diaper body further comprises a urine wetness indicator paper, and the urine wetness indicator paper is disposed on the absorbent core.
8. The urine testing device of claim 7, wherein the absorbent core comprises a nonwoven fabric surface layer, a flow guide layer, a water absorbing layer and a base film arranged in sequence; the urine wet display paper is arranged between the water absorption layer and the bottom film.
9. A computer device, comprising: a memory and one or more processors;
the memory to store one or more programs;
when executed by the one or more processors, cause the one or more processors to implement a urine detection method as claimed in any one of claims 1-5.
10. A storage medium containing computer-executable instructions for performing a urine testing method according to any one of claims 1-5 when executed by a computer processor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202210936783.9A CN115165996A (en) | 2022-08-05 | 2022-08-05 | Urine detection method and device |
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| CN202210936783.9A CN115165996A (en) | 2022-08-05 | 2022-08-05 | Urine detection method and device |
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| CN115165996A true CN115165996A (en) | 2022-10-11 |
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| CN202210936783.9A Pending CN115165996A (en) | 2022-08-05 | 2022-08-05 | Urine detection method and device |
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