CN115138444B - Preparation method and application of cefalotin cream for dairy cows - Google Patents

Preparation method and application of cefalotin cream for dairy cows Download PDF

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Publication number
CN115138444B
CN115138444B CN202210604449.3A CN202210604449A CN115138444B CN 115138444 B CN115138444 B CN 115138444B CN 202210604449 A CN202210604449 A CN 202210604449A CN 115138444 B CN115138444 B CN 115138444B
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China
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component
grinding
barrel
cream
arc
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CN115138444A (en
Inventor
赵永达
李彦
郭莉莉
王丽华
林姝君
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Qingdao Bolin Biotechnology Co ltd
Qingdao Agricultural University
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Qingdao Agricultural University
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C15/00Disintegrating by milling members in the form of rollers or balls co-operating with rings or discs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/40Parts or components, e.g. receptacles, feeding or discharging means
    • B01F29/403Disposition of the rotor axis
    • B01F29/4033Disposition of the rotor axis inclined
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00Mixers with rotating receptacles
    • B01F29/60Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80Mixing plants; Combinations of mixers
    • B01F33/83Mixing plants specially adapted for mixing in combination with disintegrating operations
    • B01F33/831Devices with consecutive working receptacles, e.g. with two intermeshing tools in one of the receptacles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/10Maintenance of mixers
    • B01F35/11Maintenance of mixers using fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C23/00Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
    • B02C23/02Feeding devices

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Confectionery (AREA)
  • Crushing And Pulverization Processes (AREA)

Abstract

The invention discloses a preparation method and application of cefalotin cream for cows, comprising a base component, wherein a mixing cylinder component which is obliquely arranged is arranged at the upper part of the base component, a driving component for realizing rotation of the mixing cylinder component is arranged at the upper part of the base component, a grinding disc component is arranged in the mixing cylinder component, a grinding ball which is matched with the grinding disc component is arranged at the middle position of the top of the base component, a flexible cover for sealing is arranged between the mixing cylinder component and the base component, the mixing cylinder component comprises a lower cylinder, the lower part of the lower cylinder is of a bucket-shaped structure, the bottom of the lower cylinder is of an opening structure, and an arc surface cover which is communicated with the inside of the lower cylinder is arranged at the opening of the lower cylinder. The invention realizes the continuous change of the positions of the grinding balls involved in grinding, thereby reducing the occurrence of material caking, better ensuring the smooth grinding, and being capable of grinding and crushing auxiliary materials such as silicon dioxide and the like better.

Description

Preparation method and application of cefalotin cream for dairy cows
Technical Field
The invention relates to the technical field of veterinary medicine preparation equipment, in particular to a preparation method and application of cefalotin cream for cows.
Background
Cellonine is a chemical substance, and the emulsion containing Cellonine is used for treating cow mastitis, which is one of common diseases endangering cow breeding industry, and about 50% of cows in the world have various types of cow mastitis, so that huge economic losses are caused to the cow breeding industry. The main cause of cow mastitis is infection by pathogenic microorganisms, of which 5 pathogenic types, especially staphylococcus aureus, streptococcus agalactiae, streptococcus uberis and various gram negative bacteria, are most common.
During the preparation process of the cefalotin emulsifiable paste, silicon dioxide raw materials are required to be ground, the existing grinding equipment is easy to produce grinding disc accumulation materials, so that the grinding effect is poor, caking and the like are easy to occur, and the medicinal effect of the product cefalotin is influenced, so that the grinding equipment for preparing the cefalotin emulsifiable paste for cows is provided.
Disclosure of Invention
Based on the technical problems in the background technology, the invention provides a preparation method and application of cefalotin cream for cows.
The invention provides a preparation method of cefalotin cream for cows, which comprises the following steps: s1: crushing the cefalonine raw material silicon dioxide to more than 90% by using grinding equipment until the particle diameter reaches 3-5 mu m, namely a material A;
s2: adding 1-5 parts of polyethylene glycol-400 and 1-4 parts of fatty alcohol-polyoxyethylene ether into 20-30 parts of liquid paraffin, stirring and mixing uniformly, continuously heating for 4-6 hours, and cooling to room temperature to obtain liquid B;
s3: feeding the material A, the liquid B, the vitamin E and the benzyl alcohol into a high-pressure homogenizing machine according to the weight ratio of 1:3:1:1, wherein the pressure is 50-150Mpa, and homogenizing is carried out for 5-10min; obtaining cefalotin cream for cows;
grinding equipment, including the base subassembly, base subassembly upper portion is provided with the compounding section of thick bamboo subassembly that the slope set up, and base subassembly upper portion is provided with and is used for realizing compounding section of thick bamboo subassembly pivoted drive assembly, be provided with grinding disc subassembly in the compounding section of thick bamboo subassembly, base subassembly top intermediate position department is provided with the grinding ball with grinding disc subassembly looks adaptation, be provided with the flexible cover that is used for sealedly between compounding section of thick bamboo subassembly and the base subassembly, compounding section of thick bamboo subassembly includes down a section of thick bamboo, lower section of thick bamboo lower part is the bucket form structure, and the lower section of thick bamboo bottom is the open structure, lower section of thick bamboo lower part opening part is provided with the cambered surface cover of intercommunication inside, cambered surface cover and grinding ball looks adaptation, lower section of thick bamboo is kept away from cambered surface cover one end and is provided with the upper cylinder, upper cylinder is kept away from lower section of thick bamboo one end and is provided with the connecting pipe of thick bamboo inside of intercommunication, and the connecting pipe is kept away from upper cylinder one end and be provided with the feeder hopper, grinding disc subassembly is including fixing at the inside first installing support of lower section of thick bamboo, first installing support top intermediate position department is fixed with the second motor, second motor is hollow motor output shaft motor, lower section of thick bamboo lower part is the hopper form structure, the cambered surface is the cambered surface cover is equipped with the cambered surface cover, and the transmission profile is the transmission blade is the arc-shaped and extends the transmission profile and extends the grinding disc, the arc is provided with the cambered surface and extends the transmission profile, the transmission blade.
As further optimization of the technical scheme, the grinding equipment for the preparation method of the cefalotin cream for the dairy cows is characterized in that arc-shaped dispersing strips distributed in an annular mode are arranged on the inner side of the arc-shaped cover, and the arc-shaped dispersing strips are in contact with the outer surface of a grinding ball.
In the preferred embodiment, the arcuate dispersion bars assist in dispersing the material and reduce the likelihood of caking.
As a further optimization of the technical scheme, one end of the transmission rod, far away from the arc-shaped grinding disc, is penetrated by the output shaft of the second motor, and one end of the transmission rod, far away from the arc-shaped grinding disc, is provided with a blowing pipe assembly, the blowing pipe assembly comprises a bent pipe, one end of the bent pipe penetrates through the connecting pipe and the feeding hopper, the other end of the bent pipe is connected with the rotary gas receiving head, and one end of the rotary gas receiving head, far away from the bent pipe, is fixedly connected with the end part of the transmission rod.
As a further optimization of the technical scheme, the grinding equipment of the preparation method of the cefalotin cream for the dairy cows is characterized in that one end, close to an arc-shaped grinding disc, of the transmission rod is provided with a blowing hole communicated with the inside of the transmission rod, and the blowing hole can release gas blown in by a blowing pipe assembly into a mixing barrel assembly so as to achieve the effect of cleaning materials.
As further optimization of the technical scheme, the grinding equipment for the preparation method of the cefalotin cream for the dairy cows is characterized in that the peripheral surface of the lower cylinder is rotationally connected with a connecting ring, and the connecting ring is fixedly connected with the upper part of the flexible cover.
As a further optimization of the technical scheme, the grinding equipment of the preparation method of the cefalotin cream for the dairy cows is characterized in that an annular cylinder is fixedly arranged on the upper portion of a base component, annular distributed teeth are arranged on the upper portion of the annular cylinder, an inclined tooth ring is arranged on the outer peripheral surface of the lower cylinder close to the position of a connecting ring, connecting struts which are distributed in an annular mode at equal intervals are arranged on the inclined tooth ring, one end, far away from the inclined tooth ring, of the connecting struts is fixedly connected with the outer peripheral surface of the lower cylinder, a motor support is arranged on the upper portion of the base component, a first motor is arranged at the bottom of the motor support, an output shaft of the motor support penetrates through the motor support to be fixed with a gear, an outer tooth ring is rotatably connected to the outer peripheral surface of the annular cylinder, the outer tooth ring is meshed with the gear, a supporting arm is arranged at the top of the outer tooth ring, the supporting arm comprises a metal arm, one end of the metal arm is fixedly connected with the top of the outer tooth ring, the metal arm is in a C-shaped structure, a rotary sleeve is arranged at the other end of the metal arm, and the rotary sleeve is rotatably connected with the outer wall.
In this preferred scheme, promote compounding section of thick bamboo subassembly through the metal arm rotatory around grinding ball, because the effect of tooth on oblique ring gear and the annular section of thick bamboo in rotatory in-process realizes compounding section of thick bamboo subassembly and takes place the rotation to reach the purpose of mixed material, and this in-process grinding ball takes part in the position of grinding and changes always again, thereby avoided the local grinding material to take place the condition emergence of caking, reached better grinding effect.
As a further optimization of the technical scheme, the grinding equipment of the preparation method of the cefalotin cream for the dairy cows comprises a vertical cylinder, wherein the lower part of the vertical cylinder is provided with a fixed ring, the fixed ring is provided with mounting holes distributed in an annular mode, the inner wall of the top of the vertical cylinder is provided with a discharging hopper, the lower part of the discharging hopper is provided with a discharging pipe, the top position of the inner wall of the discharging hopper is provided with a second mounting bracket, a grinding ball is fixedly connected with the middle position of the top of the second mounting bracket, and the lower part of the flexible cover is fixedly connected with the edge of the top of the discharging hopper.
In this preferred scheme, the mounting hole is used for carrying out fixed mounting, and the flexible cover can satisfy the position change that the motion of compounding section of thick bamboo subassembly brought.
As a further optimization of the technical scheme, the grinding equipment for the preparation method of the cefalotin cream for the dairy cows is provided with the discharging door holes on the outer peripheral surface of the vertical cylinder, and discharging can be carried out through the discharging door holes.
The invention provides application of cefalotin cream for cows in treating mastitis of cows.
In summary, the beneficial effects of the invention are as follows:
the invention provides a preparation method of cefalon cream for cows, which is characterized in that the preparation of raw materials is carried out by proportioning, the improvement is carried out in the grinding of silicon dioxide, the continuous change of the grinding ball participating in the grinding is realized by a driving component, so that the occurrence of material agglomeration is reduced, the smooth grinding is better ensured, auxiliary materials such as silicon dioxide and the like can be better ground and crushed, and simultaneously, the spiral blades are arranged, so that the blanking is convenient, the rotation of a mixing cylinder component can be realized while the rotation of the mixing cylinder component is realized, the effect of mixing materials is achieved, and the blowing pipe component and a blowing hole are combined, so that the inside of the mixing cylinder component can be cleaned by blowing.
Drawings
Fig. 1 is a schematic diagram of a preparation method and an application structure of a cefalotin cream for cows;
fig. 2 is a schematic structural diagram of a preparation method and an application base assembly of the cefalotin cream for cows;
fig. 3 is a schematic side view of a preparation method of a cefalotin cream for cows and a mixing drum assembly;
fig. 4 is a schematic diagram of the bottom structure of a preparation method and an application mixing drum assembly of the cefalotin cream for cows;
fig. 5 is a schematic structural diagram of a preparation method and an application lower barrel of the cefalotin cream for cows;
fig. 6 is a schematic diagram of a preparation method of a cefalotin cream for cows and a structure of a mixing drum assembly and a grinding ball matched with each other;
fig. 7 is a schematic structural diagram of a preparation method and application of the cefalotin cream for cows, wherein the schematic structural diagram is provided with an outer toothed ring and a supporting arm;
fig. 8 is a schematic diagram of a preparation method of a cefalotin cream for cows and a structure of a grinding disc assembly and a grinding ball applied to the method;
fig. 9 is a schematic diagram of a preparation method of a cefalonine cream for cows and a structure using an abrasive disc assembly and a blowpipe assembly according to the present invention;
fig. 10 is a schematic structural diagram of a method for preparing a cefalotin cream for dairy cows and an application grinding disc assembly.
In the figure: 1. a base assembly; 101. a vertical tube; 102. a fixing ring; 103. a mounting hole; 104. a discharge door hole; 2. a drive assembly; 201. a first motor; 202. a gear; 203. a motor bracket; 204. teeth; 205. an annular cylinder; 206. an inclined toothed ring; 207. a connecting strut; 208. an outer toothed ring; 3. a mixing barrel assembly; 301. a lower cylinder; 302. a cylinder is arranged; 303. a connecting pipe; 304. a feed hopper; 305. a connecting ring; 306. an arc mask; 307. a first mounting bracket; 308. arc-shaped dispersion strips; 4. a support arm; 401. a metal arm; 402. a rotating sleeve; 5. a blowpipe assembly; 501. rotating the gas receiving head; 502. bending the pipe; 6. a flexible cover; 7. discharging a hopper; 8. a grinding disc assembly; 801. an arc-shaped grinding disc; 802. spiral through grooves; 803. a helical blade; 804. a transmission rod; 805. a stirring arm; 806. blowing holes; 9. a second motor; 10. grinding balls; 11. and a second mounting bracket.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to fig. 1 to 10 in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
A preparation method of cefalotin cream for cows comprises the following steps:
s1: crushing the cefalonine raw material silicon dioxide to more than 90% by using grinding equipment, wherein the particle diameter reaches 4 mu m, and the material A is obtained;
s2: adding 3 parts of polyethylene glycol-400 and 2 parts of fatty alcohol-polyoxyethylene ether into 25 parts of liquid paraffin, stirring and mixing uniformly, continuously heating for 5 hours, and cooling to room temperature to obtain liquid B;
s3: feeding the material A, the liquid B, the vitamin E and the benzyl alcohol into a high-pressure homogenizing machine according to the weight ratio of 1:3:1:1, wherein the pressure is 100Mpa, and homogenizing is carried out for 7.5min; obtaining cefalotin cream for cows;
referring to fig. 1-10, the grinding device of the invention comprises a base component 1, a mixing barrel component 3 which is obliquely arranged is arranged at the upper part of the base component 1, a driving component 2 which is used for realizing rotation of the mixing barrel component 3 is arranged at the upper part of the base component 1, a grinding disc component 8 is arranged in the mixing barrel component 3, a grinding ball 10 which is matched with the grinding disc component 8 is arranged at the middle position of the top of the base component 1, a flexible cover 6 which is used for sealing is arranged between the mixing barrel component 3 and the base component 1, the mixing barrel component 3 comprises a lower barrel 301, the lower part of the lower barrel 301 is of a bucket-shaped structure, the bottom of the lower barrel 301 is of an opening structure, an arc cover 306 which is communicated with the inside of the lower barrel 301 is arranged at the opening of the lower part of the lower barrel 301, an upper barrel 302 is arranged at one end of the lower barrel 301 which is far away from the arc cover 306, a connecting pipe 303 which is communicated with the inside of the lower barrel 301 is arranged at one end of the upper barrel 302, a feeding hopper 304 is arranged at one end of the upper barrel 302, and an arc cover 306 is distributed in a dispersing ring shape and is in an arc shape 308 which is in contact with an arc-shaped outer surface 308, and the arc-shaped balls are distributed on the outer surface of the arc cover 308.
In the invention, the grinding disc assembly 8 comprises a first mounting bracket 307 fixed in the lower cylinder 301, a second motor 9 is fixed in the middle position of the top of the first mounting bracket 307, the second motor 9 is a hollow shaft motor, a transmission rod 804 is fixed on the output shaft of the second motor 9, a stirring arm 805 is arranged on the peripheral surface of the transmission rod 804, the transmission rod 804 is of a hollow structure, an arc-shaped grinding disc 801 is fixed at one end of the transmission rod 804 far away from the second motor 9, the outer edge of the arc-shaped grinding disc 801 is rotationally connected with the inner wall of the lower cylinder 301 near an opening, spiral blades 803 which are spirally extended are arranged at one end of the arc-shaped grinding disc 801 far away from a grinding ball 10, spiral penetrating grooves 802 which are spirally extended are arranged at the position of the arc-shaped grinding disc 801 near the transmission rod 804, and blowing holes 806 communicated with the inside are arranged at one end of the transmission rod 804 near the arc-shaped grinding disc 801
In the invention, one end of the transmission rod 804 far away from the arc grinding disc 801 is penetrated by an output shaft of the second motor 9, one end of the transmission rod 804 far away from the arc grinding disc 801 is provided with a blowing pipe assembly 5, the blowing pipe assembly 5 comprises a bent pipe 502, one end of the bent pipe 502 penetrates through a connecting pipe 303 and a feeding hopper 304, the other end of the bent pipe 502 is connected with a rotary gas receiving head 501, one end of the rotary gas receiving head 501 far away from the bent pipe 502 is fixedly connected with the end of the transmission rod 804, the peripheral surface of the lower cylinder 301 is rotationally connected with a connecting ring 305, the connecting ring 305 is fixedly connected with the upper part of the flexible cover 6,
in the invention, an annular cylinder 205 is fixedly arranged at the upper part of a base assembly 1, teeth 204 which are annularly distributed are arranged at the upper part of the annular cylinder 205, an inclined tooth ring 206 is arranged at the position, close to a connecting ring 305, of the outer peripheral surface of a lower cylinder 301, connecting support rods 207 which are annularly distributed at equal intervals are arranged on the inclined tooth ring 206, one end, far away from the inclined tooth ring 206, of the connecting support rods 207 is fixedly connected with the outer peripheral surface of the lower cylinder 301, a motor bracket 203 is arranged at the upper part of the base assembly 1, a first motor 201 is arranged at the bottom of the motor bracket 203, a gear 202 is fixed on an output shaft of the motor bracket 203 through the motor bracket 203, an outer tooth ring 208 is rotatably connected to the outer peripheral surface of the annular cylinder 205, the outer tooth ring 208 is meshed with the gear 202, the external tooth ring 208 top is provided with support arm 4, support arm 4 includes metal arm 401, and metal arm 401 one end and external tooth ring 208 top fixed connection, metal arm 401 is C type structure, metal arm 401 other one end is provided with swivel sleeve 402, swivel sleeve 402 forms the rotation with connecting pipe 303 outer wall and is connected, promotes compounding section of thick bamboo subassembly 3 through metal arm 401 and rotates around grinding ball 10, because the effect of tooth 204 on oblique tooth ring 206 and the annular section of thick bamboo 205 in the rotatory in-process, realizes compounding section of thick bamboo subassembly 3 and takes place the rotation to reach the purpose of mixed material, and the position that this in-process grinding ball 10 participated in the grinding changes always again, thereby avoided the local grinding material to take place the condition emergence of caking, reached better grinding effect.
According to the invention, the base assembly 1 comprises a vertical cylinder 101, a fixed ring 102 is arranged at the lower part of the vertical cylinder 101, mounting holes 103 distributed in a ring shape are arranged on the fixed ring 102, a discharging door hole 104 is arranged on the outer peripheral surface of the vertical cylinder 101, a discharging hopper 7 is arranged on the inner wall of the top of the vertical cylinder 101, a discharging pipe is arranged at the lower part of the discharging hopper 7, a second mounting bracket 11 is arranged at the top position of the inner wall of the discharging hopper 7, a grinding ball 10 is fixedly connected with the middle position of the top of the second mounting bracket 11, and the lower part of the flexible cover 6 is fixedly connected with the top edge of the discharging hopper 7.
Working principle: the cefalonium cream raw materials that need grind the processing are thrown into compounding section of thick bamboo subassembly 3 through feeder hopper 304, the work of second motor 9 drives the transfer line 804 and rotates, thereby drive arc grinding dish 801 and helical blade 803 rotation, stirring arm 805 stirs the material, helical blade 803 gathers the material to the centre, make things convenient for the material to enter into spiral through groove 802, partial material passes spiral through groove 802 and enters into the clearance between arc grinding dish 801 and the grinding ball 10, realize grinding under the rotatory circumstances of arc grinding dish 801 again, the clearance between arc face guard 306 and the grinding ball 10 is passed to the material after grinding, and disperse and fall into down in hopper 7 under the cooperation of arc dispersion strip 308, finally be discharged by the discharging pipe of hopper 7 lower part down, work through control first motor 201, cooperation gear 202 and external tooth ring 208 effect, drive support arm 4 rotation, oblique tooth ring 206 and tooth 204 that the cooperation set up, realize compounding section of thick bamboo subassembly 3, in compounding section of thick bamboo subassembly 3 around grinding ball 10 rotary process, can not only change grinding position of grinding ball 10, thereby avoid the grinding that the material is stained with the poor problem that leads to, simultaneously, can blow down the problem that the rotation of material can be blown out in the rotation subassembly 3, can reach the high-pressure mixing material through the stirring effect, blow out the material can blow down the hole 806, can be realized by the blast down the mixing material component, the material can blow down the problem that the material can be blown out.
Spatially relative terms, such as "above … …," "above … …," "upper surface at … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial location relative to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the exemplary term "above … …" may include both orientations of "above … …" and "below … …". The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments in accordance with the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
It should be noted that the terms "first," "second," and the like in the description and claims of the present application and the above figures are used for distinguishing between similar objects and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used may be interchanged where appropriate such that embodiments of the present application described herein may be capable of being practiced otherwise than as specifically illustrated and described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.

Claims (9)

1. The preparation method of the cefalotin cream for the dairy cows is characterized by comprising the following steps of:
s1: crushing the cefalonine raw material silicon dioxide to more than 90% by using grinding equipment until the particle diameter reaches 3-5 mu m, namely a material A;
s2: adding 1-5 parts of polyethylene glycol-400 and 1-4 parts of fatty alcohol-polyoxyethylene ether into 20-30 parts of liquid paraffin, stirring and mixing uniformly, continuously heating for 4-6 hours, and cooling to room temperature to obtain liquid B;
s3: feeding the material A, the liquid B, the vitamin E and the benzyl alcohol into a high-pressure homogenizing machine according to the weight ratio of 1:3:1:1, wherein the pressure is 50-150Mpa, and homogenizing is carried out for 5-10min; obtaining cefalotin cream for cows;
the grinding equipment comprises a base component (1), wherein a mixing barrel component (3) which is obliquely arranged is arranged on the upper part of the base component (1), a driving component (2) which is used for realizing rotation of the mixing barrel component (3) is arranged on the upper part of the base component (1), a grinding disc component (8) is arranged in the mixing barrel component (3), a grinding ball (10) which is matched with the grinding disc component (8) is arranged in the middle position of the top of the base component (1), and a flexible cover (6) which is used for sealing is arranged between the mixing barrel component (3) and the base component (1);
the mixing barrel assembly (3) comprises a lower barrel (301), wherein the lower part of the lower barrel (301) is of a bucket-shaped structure, the bottom of the lower barrel (301) is of an opening structure, an arc surface cover (306) communicated with the inside of the lower barrel is arranged at the opening of the lower part of the lower barrel (301), the arc surface cover (306) is matched with the grinding ball (10), an upper barrel (302) is arranged at one end, away from the arc surface cover (306), of the lower barrel (301), a connecting pipe (303) communicated with the inside of the lower barrel is arranged at one end, away from the lower barrel (301), of the upper barrel (302), and a feed hopper (304) is arranged at one end, away from the upper barrel (302), of the connecting pipe (303);
the grinding disc assembly (8) comprises a first mounting bracket (307) fixed inside the lower cylinder (301), a second motor (9) is fixed at the middle position of the top of the first mounting bracket (307), the second motor (9) is a hollow shaft motor, a transmission rod (804) is fixed on an output shaft of the second motor (9), a stirring arm (805) is arranged on the outer peripheral surface of the transmission rod (804), the transmission rod (804) is of a hollow structure, an arc-shaped grinding disc (801) is fixed at one end of the transmission rod (804) far away from the second motor (9), the outer edge of the arc-shaped grinding disc (801) is connected with the inner wall of the lower cylinder (301) in a rotating mode, a spiral blade (803) which is spirally extended and distributed is arranged at one end of the arc-shaped grinding disc (801), and a spiral penetrating groove (802) which is spirally extended and distributed is arranged at the position of the arc-shaped grinding disc (801) near the transmission rod (804).
2. The method for preparing the cefalonine cream for the dairy cows according to claim 1, wherein arc-shaped dispersing strips (308) distributed in an annular shape are arranged on the inner side of the cambered surface cover (306), and the arc-shaped dispersing strips (308) are in contact with the outer surface of the grinding ball (10).
3. The preparation method of the cefaloning cream for the dairy cows according to claim 2, wherein one end of a transmission rod (804) far away from an arc grinding disc (801) is penetrated by an output shaft of a second motor (9), one end of the transmission rod (804) far away from the arc grinding disc (801) is provided with a blowing pipe assembly (5), the blowing pipe assembly (5) comprises a bent pipe (502), one end of the bent pipe (502) penetrates through a connecting pipe (303) and a feeding hopper (304), the other end of the bent pipe (502) is connected with a rotary gas joint (501), and one end of the rotary gas joint (501) far away from the bent pipe (502) is fixedly connected with the end of the transmission rod (804).
4. A method for preparing a cefaloning cream for cows according to claim 3, wherein one end of the transmission rod (804) close to the arc-shaped grinding disc (801) is provided with a blowing hole (806) communicated with the inside.
5. A method for preparing a cefalotin cream for dairy cows according to claim 2 or 3, wherein a connecting ring (305) is rotatably connected to the outer peripheral surface of the lower cylinder (301), and the connecting ring (305) is fixedly connected to the upper part of the flexible cover (6).
6. The preparation method of the cefalonine cream for cows according to claim 5, wherein an annular cylinder (205) is fixedly arranged at the upper part of the base assembly (1), annular teeth (204) are annularly distributed at the upper part of the annular cylinder (205), an inclined tooth ring (206) is arranged at the position, close to a connecting ring (305), of the outer peripheral surface of the lower cylinder (301), connecting struts (207) which are annularly distributed at equal intervals are arranged on the inclined tooth ring (206), one end, far away from the inclined tooth ring (206), of the connecting struts (207) is fixedly connected with the outer peripheral surface of the lower cylinder (301), a motor bracket (203) is arranged at the upper part of the base assembly (1), a first motor (201) is arranged at the bottom of the motor bracket (203), an output shaft of the motor bracket (203) penetrates through the motor bracket (203) to be fixedly provided with a gear (202), an outer peripheral surface of the annular cylinder (205) is rotationally connected with an outer tooth ring (208), the outer tooth ring (208) is meshed with the gear (202), a supporting arm (4) is arranged at the top of the outer tooth ring (208), one end, far away from the inclined tooth ring (206), of the metal arm (401) is fixedly connected with the outer tooth ring (401), one end of the other end of the metal arm (401) is fixedly connected with the metal arm (401), one end of the other end of the metal arm (401) is fixedly provided with an outer tooth (401), the rotary sleeve (402) is in rotary connection with the outer wall of the connecting pipe (303).
7. The preparation method of the cefalonine cream for cows according to claim 6, wherein the base component (1) comprises a vertical barrel (101), a fixing ring (102) is arranged at the lower part of the vertical barrel (101), mounting holes (103) distributed in a ring shape are formed in the fixing ring (102), a discharging hopper (7) is arranged on the inner wall of the top of the vertical barrel (101), a discharging pipe is arranged at the lower part of the discharging hopper (7), a second mounting bracket (11) is arranged at the top position of the inner wall of the discharging hopper (7), a grinding ball (10) is fixedly connected with the middle position of the top of the second mounting bracket (11), and the lower part of the flexible cover (6) is fixedly connected with the edge of the top of the discharging hopper (7).
8. The method for preparing the cefalonine cream for cows as claimed in claim 7, wherein the outer circumferential surface of the vertical cylinder (101) is provided with a discharge gate hole (104).
9. Use of a cefalotin cream for cows according to any of claims 1-8 for the treatment of mastitis in cows.
CN202210604449.3A 2022-05-31 2022-05-31 Preparation method and application of cefalotin cream for dairy cows Active CN115138444B (en)

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