CN115104613B - Pesticide composition containing pyrazole amide compound of diphenyl ether - Google Patents

Abstract

The invention relates to a pesticide composition containing a pyrazole amide compound of diphenyl ether, which is prepared by combining the pyrazole amide compound of diphenyl ether with a specific pesticide active compound, has excellent prevention or control effect on plant diseases under low dosage and does not worry about phytotoxicity on useful plants. The pesticide composition contains a component I and a component II as active ingredients, wherein the component I is a pyrazole amide compound shown in a formula I, the component II is penconazole, and the weight ratio of the component I to the component II is 20:1-1:10.

Description

Pesticide composition containing pyrazole amide compound of diphenyl ether

Technical Field

The invention discloses a pesticide composition containing a pyrazole amide compound of diphenyl ether, and relates to a pesticide composition containing a specific pesticide active ingredient. The composition of the present invention exhibits an excellent control effect on plant diseases at a low dosage without fear of phytotoxicity to useful plants.

Background

In the cultivation of crops, various agricultural chemical compositions are required to be used for controlling diseases, weeds and pests. Pesticide compositions typically contain a pesticide active ingredient, and a surfactant for stabilizing the efficacy of the pesticide active ingredient or even enhancing the efficacy.

However, the use of conventional agricultural chemical compositions for preventing or controlling plant diseases is limited by insufficient efficacy, occurrence of drug-resistant pathogenic bacteria, or phytotoxicity or pollution to plants, or toxicity to humans, animals and fish, environmental impact, and the like.

Therefore, it is desired to develop a pesticidal composition which can be safely used and has a high efficacy for preventing or controlling plant diseases.

Disclosure of Invention

The purpose of the present invention is to provide a pesticidal composition containing a pyrazole amide compound, which exhibits an excellent preventive or control effect on plant diseases with a low dosage and does not have to worry about phytotoxicity to useful plants.

The present inventors have further studied a bactericide composition containing a pyrazole amide compound containing diphenyl ether as an active ingredient described in CN104557709 in order to solve the above-mentioned problems.

The present inventors have surprisingly found that by combining the above-mentioned one pyrazole amide compound containing diphenyl ether with a specific pesticidal active compound, an excellent preventive or controlling effect on plant diseases can be exhibited at a low dosage without fear of causing phytotoxicity to useful plants.

The invention is realized by adopting the following technical scheme:

a pesticide composition containing pyrazole amide compounds of diphenyl ether contains component I and component II as active ingredients, wherein component I is pyrazole amide compound shown in formula I, and component II is penconazole.

Surprisingly, it has now been found that compositions of component I and component II exhibit unexpectedly synergistic toxic effects. And also shows markedly synergistically increased activity even against plant pathogenic fungi whose sensitivity to triazole-based bactericides has been reduced.

The preferred weight ratios of component I and component II are I:II=20:1 to 1:10, preferably I:II=10:1 to 1:10, more preferably 10:1 to 1:5; more preferably 8:1 to 1:4.

The pesticide composition is used for preventing or controlling plant diseases.

The pesticide composition is used for preventing or controlling powdery mildew of cucumber, powdery mildew of wheat, rice sheath blight and phytophthora infestans of potatoes.

A method for preventing or controlling plant diseases, which comprises applying the pesticidal composition to an aerial part of a plant, a plant seed or soil for cultivating a plant.

The pesticide composition contains a component I and a component II, and a carrier and/or a surfactant.

The pesticide composition is prepared from solution, emulsion, emulsifiable concentrate, wettable powder, suspension, paste, water dispersible granule, suspending emulsion, microcapsule emulsifiable concentrate, aqueous emulsion, aqueous suspension, dry suspension, emulsion, ultra-low volume liquid, water dispersible granule, wettable powder, granule and microcapsule.

The pesticide composition has very excellent treatment, prevention and systemic sterilization performance for protecting crops. It can effectively control the following plant pathogenic fungi:

ascomycetes (e.g., the genus black star, the genus leptosphaeria, the genus powdery mildew, the genus candida, the genus leptosphaeria);

basidiomycetes (e.g., camelina, rhizoctonia, and puccinia);

fungi imperfecti (e.g., botrytis, helminthosporium, roxburgh, fusarium, septoria, cercospora, alternaria, pyricularia);

oomycetes (e.g., phytophthora, downy mildew, pythium).

More preferable diseases to which the pesticide composition of the present invention is applied include powdery mildew of cucumber, powdery mildew of wheat, sheath blight of rice, and phytophthora root rot of potato.

Target crops to which the pesticidal composition of the present invention is applicable are, for example, the following plant species: grains (wheat, barley, rye, oats, rice, sorghum and related varieties); cucumber, melon like melon; fruits, stone fruits and berries (apples, pears, plums, peaches, apricots, cherries, strawberries, raspberries, blackberries); legume crops (fava beans, lentils, peas, soybeans); beet (sugar beet and fodder beet); oil crops (oilseed rape, mustard, poppy, olives, sunflowers, coconuts, castor beans, cocoa, peanuts); pumpkin (cucurbits); cucumber, melon like melon; fiber plants (cotton, flax, hemp, jute); citrus fruit (orange, lemon, grapefruit, red Pi Jie); various vegetables (spinach, lettuce, asparagus, cabbages, carrots, shallots, tomatoes, potatoes, bell peppers); lauraceae (fructus Pyri, cortex Cinnamomi Japonici, camphora); or plants such as maize, tobacco, nuts, coffee, sugar cane, tea, grape, hops, musaceae and natural rubber plants, as well as ornamental plants (flowers, shrubs, deciduous and conifers, e.g. conifers).

The preferred method of application of the pesticide compositions of the present invention is to apply them to the aerial parts of the plants, in particular to the leaves (foliar application).

The pesticide compositions according to the invention can also be used as seed coating agents for the treatment of seeds (fruits, tubers, seeds) and cuttings against fungal infections and against soil-borne phytopathogenic fungi, because of their systemic action.

The pesticide compositions according to the invention are distinguished by their good environmental benefits and in particular by their good resistance to plants.

Component I and component II are generally used in combination. Component I and component II may be applied simultaneously or consecutively on the same day to the area or plant to be treated, if desired together with other carriers, surfactants or use-promoting additives commonly used in the field of formulation.

Suitable surfactants may be nonionic, cationic and/or anionic surfactants, all of which have good emulsifying, dispersing and wetting properties. Such as naphthalene sulfonic acid polymers, lignin sulfonates, branched copolymers of polymeric combs, butylnaphthalene sulfonates, alkylaryl sulfonates, alkyl sulfosuccinates, oils, condensates of fatty alcohols with ethylene oxide, polyacrylates of alkyl naphthalene sulfonates, polyoxyethylene higher fatty acid esters, phosphate esters of polyoxyethylene alcohols or phenols, fatty alcohol polyoxyethylene ethers, polyoxyethylene alkylaryl ethers, fatty acid esters of polyols, protein hydrolysates, suitable oligosaccharides or polymers, for example based on ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with, for example, (poly) alcohols or (poly) amines.

Suitable carriers may be solid carriers or liquid carriers. Suitable liquid carriers can be water, aromatic hydrocarbons, isopropanol, butanol, tetrahydrofuran, ethylene glycol, propylene glycol, ethyl acetate, methyl oleate, dimethylformamide, dimethylacetamide, dimethylsulfoxide, vegetable oils and the like.

Suitable solid carriers are generally ground natural minerals such as talc, bentonite, clay, kaolin, diatomaceous earth, white carbon, calcium carbonate, acid clay, silica, zeolite, attapulgite, pumice, ammonium sulfate, sodium sulfate and urea.

The components I and II in the pesticidal composition according to the present invention are preferably used together with adjuvants commonly used in the field of formulation processing. Can be produced according to a known method to obtain, for example, emulsifiable concentrates, aqueous emulsions, aqueous suspensions, dry suspensions, emulsion granules, ultra-low volume liquids, water dispersible granules, wettable powders, granules, microcapsules and the like.

A pesticidal composition containing a pyrazole amide compound which exhibits an excellent preventive or controlling effect on plant diseases with a low dosage without fear of causing phytotoxicity to useful plants. A pesticide composition containing pyrazole amide compounds of diphenyl ether contains component I and component II as active ingredients, wherein component I is pyrazole amide compound shown in formula I, and component II is penconazole. The compositions of component I and component II exhibit unexpectedly synergistic toxic effects and show markedly increased activity even against phytopathogenic fungi whose sensitivity to triazole fungicides has been reduced.

Detailed Description

Formulation examples

Wettable powder

The active component and the additive are fully mixed, and the mixture is fully ground in a grinder to obtain wettable powder.

Emulsifiable concentrate

Emulsifiable concentrates are prepared by homogeneously mixing the above components and dissolving.

Water dispersible granule

The active ingredient is mixed with additives, ground, and moistened with water. The mixture is extruded and then dried in an air stream. The above examples are prepared by weight.

Biological test case

When the bactericidal activity of an active ingredient composition exceeds the sum of the activities of the individual active ingredients, there is often a synergistic effect in bactericides.

The expected effect of a particular combination of two active compounds can be calculated using the so-called "Colby formula" (see s.r. Colby, "Calculating Synergistic and Antagonistic Responses of Herbicide Combinations", wells 1967,15, 20-22) as follows:

x is the control effect when component (A) is used in an amount of m g/ha or at a concentration of m ppm;

y is the control effect when component (B) is used in an amount of n g/ha or at a concentration of n ppm;

e is the theoretical control effect when components (A) and (B) are used in amounts of m and n g/ha or in concentrations of m and n ppm,

if the actual observed activity exceeds the desired activity, the composition has a synergistic effect on its activity.

Example 1 control of tomato late blight

The raw medicines of the component I and the component II are respectively dissolved by acetone to prepare mother solution of a single dose, and then are diluted to the required concentration by aqueous solution containing 0.1% of Tween-80.

The bactericidal activity of the agent against tomato late blight was determined by a living potting method. Tomato seedlings are planted in a plastic basin, and the substrate is a vegetable planting substrate. Culturing in pot to 2-4 pieces of true leaf stage for use.

Culturing pathogenic bacteria for test on a proper culture medium, and after sporangia is generated, 4 ^o Washing sporangium with distilled water, filtering with double gauze, and making into sporangium suspension (2×10) ⁵ ~3×10 ⁵ personal/mL), placed in 8-10 ^o C, standby at low temperature.

And selecting potted tomato seedlings with consistent growth vigor. And uniformly spraying stems and leaves of the potted seedlings to be tested. The front and back sides of the leaves to be inoculated are sprayed with each treatment agent until wet. After 24 hours, the tomato leaves are evenly sprayed and inoculated on the back surface of the tomato leaves by an inoculation sprayer. For each treatment of 3 pots, 4 replicates were performed. And a treatment without a drug (containing an organic solvent and an emulsifier) was used as a blank.

The tomato seedlings are alternately irradiated with light/dark continuously for 12 hours each day after inoculation, the irradiation intensity is 10000Lux, and the temperature is 18 ^O C -20 ^O C, maintaining a water film on the leaf surface within 24 hours after inoculation, and culturing for 5 days under the condition that the relative humidity is more than 90%.

And when the leaf rate of the blank control reaches more than 50%, the disease conditions of all treatments are investigated in a grading way. The grading method comprises the following steps:

level 0: no disease spots;

stage 1: the area of the disease spots accounts for less than 10% of the whole leaf area;

3 stages: the area of the lesion accounts for 10% -25% of the whole leaf area;

5 stages: the area of the lesion accounts for 25% -50% of the whole leaf area;

7 stages: the area of the disease spots accounts for more than 50% of the whole leaf area;

stage 9: whole leaves withered.

The disease index and the control effect are calculated according to the following formula.

The composition of the invention has the effect of preventing and controlling tomato late blight

The combination of the component I and the component II not only can prevent and treat late blight, but also can prevent and treat rice sheath blight, cucumber powdery mildew and gray mold and other germs to obtain obviously improved activity.

Claims (4)

1. The application of the pesticide composition containing the pyrazole amide compound of the diphenyl ether in preventing or controlling phytophthora infestans is characterized by comprising an active ingredient of a component I and a component II, wherein the component I is the pyrazole amide compound shown in a formula I, the component II is penconazole, the weight ratio of the component I to the component II is 2:1-8:1,

formula I.

2. Use according to claim 1, characterized in that the pesticide composition contains component I and component II, a carrier and/or a surfactant.

3. The use according to claim 1, wherein the pesticidal composition is formulated in the form of a solution, emulsion, emulsifiable concentrate, wettable powder, paste, water dispersible granule, suspoemulsion, microcapsule, aqueous emulsion, aqueous suspension, dry suspension, emulsion, ultra low volume liquid, granule.

4. The use according to claim 1, wherein the plant disease caused by phytophthora infestans is potato late blight, tomato late blight.