CN1150908C - Seahorse powder capsule - Google Patents
Seahorse powder capsule Download PDFInfo
- Publication number
- CN1150908C CN1150908C CNB01135691XA CN01135691A CN1150908C CN 1150908 C CN1150908 C CN 1150908C CN B01135691X A CNB01135691X A CN B01135691XA CN 01135691 A CN01135691 A CN 01135691A CN 1150908 C CN1150908 C CN 1150908C
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- China
- Prior art keywords
- hippocampus
- temperature
- hours
- powder
- shelf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a sea horse powder capsule which is characterized in that the preparation method of the sea horse powder capsule comprises the steps: the viscera and the external grey black leather diaphragm of a fresh sea horse are removed; the processed sea horse is refrigerated for 2 to 5 hours in a refrigeration container, and the temperature is from 2 to 5 DEG C; the processed sea horse is put on a shelf board of a freeze-drying container, the temperature is regulated to 38 DEG C below zero to 40 DEG C below zero, and the sea horse is frozen for 2 to 3 hours; the pressure is regulated to 12.5 to 13.3Pa; the pressure is reduced to 1.3 to 1.33Pa; the temperature of a condenser is regulated to 57 DEG C below zero to 60 DEG C below zero; the temperature of the shelf board is slowly increased to 9 to 10 DEG C from 38 DEG C below zero to 40 DEG C below zero; and the time is from 9 to 13 hours.
Description
Technical field
The invention provides a kind of Seahorse powder capsule after lyophilization, belong to health product and technical field of medicaments.
Background technology
Hippocampus mainly contains Hippocampus polysaccharide, aminoacid, multivitamin, calcium, ferrum and trace element; Also contain a kind of active substance in the hippocampus, show as the effect of androgen sample.Effects such as Hippocampus has kidney invigorating and YANG supporting, the calmness of calming the nerves, dispersing swelling and dissipating binds, relaxing muscles and tendons and activating QI and blood in the collateral, relieving cough and asthma.Be used for the treatment of sexual impotence, sterile, lassitude loin and legs, anemofrigid lumbago, sleeplessness, asthma, injury from falling down, traumatic hemorrhage, the stasis of blood diseases such as stomachache, difficult labour that stagnate clinically.
Past people is mainly processed Hippocampus by the following method:
After catching internal organs are removed, dried.Shortcoming is that dry generally will can be dry through 2~3 talentes, and the intravital active ingredient changeableness of Hippocampus is vulnerable to destroy; And dry the influence that also is subjected to Changes in weather.
Summary of the invention
The purpose of this invention is to provide a kind of Seahorse powder capsule that contains the effect of biological activity androgen sample.
The present invention realizes by following production method:
The Hippocampus that catches is soon removed internal organs and outside grey black epithelium, place in the pallet, be placed in the cold closet cold preservation 2~5 hours, temperature is 2~5 ℃; Place then on the shelf in the drying baker of freezer dryer, shop Hippocampus amount is 8~10kg/m
2, open refrigeration plant, be-40~-38 ℃ by the cryovial in the shelf with the thermoregulation in the drying baker, Hippocampus was freezed 2~3 hours; Open oil-sealed rotary pump, make the drying baker internal pressure be adjusted to 12.5~13.3Pa; Open Roots vaccum pump, pressure is reduced to 1.3~1.33Pa; Ice in the Hippocampus of having freezed this moment promptly distils and becomes steam; Open condenser, temperature is adjusted to-60~-57 ℃, and steam is promptly become frost on condenser; Open heating system, shelf temperature slowly is heated to 9~10 ℃, this process 9~13 hours from-40~-38 ℃; Slowly shelf temperature is heated to 28~30 ℃, this process 7~9 hours; Condenser is caught the water yield and is accounted for 65~85% of gross mass, promptly gets dry Hippocampus; Pack, the Hippocampus that gets product re-uses the low temperature powder beater and makes 50~200 purpose powders, promptly gets the Hippocampus powder; With the Hippocampus powder capsulae vacuus of packing into, promptly get the lyophilizing Seahorse powder capsule.
The advantage of technology of the present invention is: because Hippocampus is placed in the cold closet after the cold preservation, place and carry out cold drying in the freezer dryer, kept in the hippocampus active ingredient androgen sample material etc. and be not destroyed.Dried Hippocampus promptly packs, and long shelf-life is difficult for mouldy.
The specific embodiment
The present invention is further described below in conjunction with embodiment:
Example 1: the LGJ-1 type freezer dryer that adopts Shanghai medical analytical instrument factory to produce, the Hippocampus that catches is soon removed internal organs and outside grey black epithelium, place in the pallet, be placed in the cold closet cold preservation 5 hours, temperature is 5 ℃; Place on the shelf in the drying baker of freezer dryer shelf effective area 1.00m then
2, shop Hippocampus amount is opened refrigeration plant for 10kg, is-40 ℃ by the cryovial in the shelf with the thermoregulation in the drying baker, and Hippocampus was freezed 3 hours; Open oil-sealed rotary pump, make the drying baker internal pressure be adjusted to 13.3Pa; Open Roots vaccum pump, pressure is reduced to 1.33Pa; Ice in the Hippocampus of having freezed this moment promptly distils and becomes steam; Open condenser, temperature is adjusted to-60 ℃, and steam is promptly become frost on condenser; Open heating system, shelf temperature slowly is heated to 10 ℃, this process 13 hours from-40 ℃; Slowly shelf temperature is heated to 30 ℃, this process 9 hours; Condenser is caught the water yield and is accounted for 85% of gross mass, promptly gets dry Hippocampus; Pack, the Hippocampus that gets product re-uses the low temperature powder beater and makes 200 purpose powders, promptly gets the Hippocampus powder.
Above Hippocampus powder adopts the pasteurization sterilization to be finished product.With the Hippocampus powder capsulae vacuus of in sterilizing room, packing into, promptly get Seahorse powder capsule.
Example 2: all technologies are with example 1, and difference is: earlier Hippocampus is put into household freezer and freezed 5 hours, temperature is-10 ℃, and the reuse powder beater is beaten powder, needn't sieve, and places then on the shelf in the freezer dryer.
Claims (1)
1, a kind of production method of Seahorse powder capsule is characterized in that: Seahorse powder capsule is that the Hippocampus that catches is soon removed internal organs, outside grey black epithelium, places in the pallet, is placed in the cold closet cold preservation 2~5 hours, and temperature is 2~5 ℃; Place then on the shelf in the drying baker of freezer dryer, shop Hippocampus amount is 8~10kg/m
2, open refrigeration plant, be-40~-38 ℃ by the cryovial in the shelf with the thermoregulation in the drying baker, Hippocampus was freezed 2~3 hours; Open oil-sealed rotary pump, make the drying baker internal pressure be adjusted to 12.5~13.3Pa; Open Roots vaccum pump, pressure is reduced to 1.3~1.33Pa; Ice in the Hippocampus of having freezed this moment promptly distils and becomes steam; Open condenser, temperature is adjusted to-60~-57 ℃, and steam is promptly become frost on condenser, opens heating system, earlier shelf temperature slowly is heated to 9~10 ℃, this process 9~13 hours from-40~-38 ℃; Slowly shelf temperature is transferred to 28~30 ℃ again, this process 7~9 hours; Condenser is caught the water yield and is accounted for 65~85% of gross mass, promptly gets the lyophilizing Hippocampus, and the lyophilizing Hippocampus is made 50~200 purpose powders with the low temperature powder beater, promptly gets the Hippocampus powder, with the Hippocampus powder capsulae vacuus of packing in sterilizing room, promptly gets Seahorse powder capsule.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB01135691XA CN1150908C (en) | 2001-10-19 | 2001-10-19 | Seahorse powder capsule |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB01135691XA CN1150908C (en) | 2001-10-19 | 2001-10-19 | Seahorse powder capsule |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1347701A CN1347701A (en) | 2002-05-08 |
CN1150908C true CN1150908C (en) | 2004-05-26 |
Family
ID=4673267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB01135691XA Expired - Fee Related CN1150908C (en) | 2001-10-19 | 2001-10-19 | Seahorse powder capsule |
Country Status (1)
Country | Link |
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CN (1) | CN1150908C (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103271944B (en) * | 2013-05-14 | 2014-03-19 | 海南通用同盟药业有限公司 | Full-powder type capsule preparation |
CN106472654A (en) * | 2016-10-21 | 2017-03-08 | 深圳市万骐海洋生物科技有限公司 | A kind of Mare Humorum horse freeze drying process |
CN106720180B (en) * | 2016-11-23 | 2020-05-19 | 深圳市万骐海洋生物科技有限公司 | Wet hippocampus air drying and drying process |
CN112315983A (en) * | 2020-11-09 | 2021-02-05 | 厦门市健康医疗大数据中心(厦门市医药研究所) | Hippocampus preparation and its preparing method and use |
-
2001
- 2001-10-19 CN CNB01135691XA patent/CN1150908C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1347701A (en) | 2002-05-08 |
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C06 | Publication | ||
C10 | Entry into substantive examination | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20040526 Termination date: 20091119 |