CN115066261A - 一种酶和病毒的药物组合及其应用 - Google Patents
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Abstract
本发明公开了一种药物组合，其包含：1)降低Fc受体与内源性血清抗体结合的试剂，其中，所述试剂包括免疫球蛋白降解酶或者糖苷内切酶，和2)病毒载体药物，其中，所述病毒载体药物选自溶瘤病毒、病毒疫苗；并且其中所述药物组合允许所述病毒载体药物和所述试剂的单独给药。本发明还公开了所述药物组合在制备治疗或预防疾病的药物中的应用，和将药物组合施用于受试者来治疗或预防癌症或感染的方法。
Description
PCT国内申请，说明书已公开。
Claims (28)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010507997 | 2020-06-05 | ||
| CN2020105079975 | 2020-06-05 | ||
| PCT/CN2021/098263 WO2021244628A1 (zh) | 2020-06-05 | 2021-06-04 | 一种酶和病毒的药物组合及其应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115066261A true CN115066261A (zh) | 2022-09-16 |
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| CN202180013742.6A Pending CN115066261A (zh) | 2020-06-05 | 2021-06-04 | 一种酶和病毒的药物组合及其应用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230277633A1 (zh) |
| EP (1) | EP4162951A4 (zh) |
| JP (1) | JP2023529186A (zh) |
| CN (1) | CN115066261A (zh) |
| WO (1) | WO2021244628A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118497176A (zh) * | 2024-07-16 | 2024-08-16 | 苏州康聚生物科技有限公司 | 一种免疫球蛋白降解酶 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2024006855A1 (en) * | 2022-06-30 | 2024-01-04 | Sarepta Therapeutics, Inc. | Methods of treating muscular dystrophy |
| TW202416993A (zh) * | 2022-08-15 | 2024-05-01 | 瑞士商赫孚孟拉羅股份公司 | 預防或減輕與重組病毒載體相關的不良反應 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201201314D0 (en) * | 2012-01-26 | 2012-03-07 | Isis Innovation | Composition |
| GB201502306D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| GB201502305D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| SG11201806134SA (en) * | 2016-01-27 | 2018-08-30 | Oncorus Inc | Oncolytic viral vectors and uses thereof |
| US20210228738A1 (en) * | 2017-07-17 | 2021-07-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins |
| WO2020102740A2 (en) | 2018-11-16 | 2020-05-22 | Spark Therapeutics, Inc. | Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins |
-
2021
- 2021-06-04 JP JP2022574838A patent/JP2023529186A/ja active Pending
- 2021-06-04 CN CN202180013742.6A patent/CN115066261A/zh active Pending
- 2021-06-04 EP EP21816711.2A patent/EP4162951A4/en active Pending
- 2021-06-04 US US18/000,516 patent/US20230277633A1/en active Pending
- 2021-06-04 WO PCT/CN2021/098263 patent/WO2021244628A1/zh unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118497176A (zh) * | 2024-07-16 | 2024-08-16 | 苏州康聚生物科技有限公司 | 一种免疫球蛋白降解酶 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP4162951A4 (en) | 2024-07-10 |
| WO2021244628A1 (zh) | 2021-12-09 |
| JP2023529186A (ja) | 2023-07-07 |
| EP4162951A1 (en) | 2023-04-12 |
| US20230277633A1 (en) | 2023-09-07 |
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