CN115023138A - Quantitative spray aerosol product for controlling specific harmful substances, and method for controlling specific harmful substances using same - Google Patents
Quantitative spray aerosol product for controlling specific harmful substances, and method for controlling specific harmful substances using same Download PDFInfo
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- CN115023138A CN115023138A CN202180010408.5A CN202180010408A CN115023138A CN 115023138 A CN115023138 A CN 115023138A CN 202180010408 A CN202180010408 A CN 202180010408A CN 115023138 A CN115023138 A CN 115023138A
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- specific
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
- A01N25/06—Aerosols
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
Abstract
The invention provides a constant-volume-spraying aerosol product for controlling specific harmful substances, which can exert excellent control effect on the specific harmful substances containing harmful microorganisms and/or harmful fine substances. The aerosol product for controlling a specific noxious substance is a specific noxious substance-controlling metered dose aerosol product for controlling a specific noxious substance containing a noxious microorganism and/or a noxious fine substance in a space, wherein the specific noxious substance-controlling metered dose aerosol product is obtained by filling an aerosol collagen liquid containing a specific noxious substance-controlling component and an organic solvent, and a propellant in an aerosol container provided with a metered dose injection valve, the aerosol collagen liquid has a specific gravity of 0.76 to 0.95 at 20 ℃, and the internal pressure in the aerosol container is set to 0.60MPa or less at 25 ℃.
Description
Technical Field
The present invention relates to: a metered-dose aerosol formulation for controlling a specific noxious substance (particularly, mold, bacteria, virus) containing a noxious microorganism and/or a noxious fine substance in a space (particularly, a narrow space); and a method for controlling a specific harmful substance using the product.
Background
A constant-volume aerosol product that can spray a constant volume of a drug by 1-time spraying is widely used as an insecticidal aerosol product (for example, see patent document 1) or a deodorant aerosol product (for example, see patent document 2) because of its convenience.
The aerosol product of patent document 1 is a constant-volume aerosol product capable of improving pest control efficiency in a spray state in which the contents of the aerosol product having a function of jetting a predetermined constant volume with a large force.
The aerosol product of patent document 2 is a constant-volume-dispensing aerosol product that exhibits an excellent deodorizing effect not only on a space but also on a malodorous substance on the floor by quantitatively dispensing an aerosol composition containing a specific amount of a deodorizing component so as to have a specific spray particle diameter.
Prior art documents
Patent document
Patent document 1: japanese patent laid-open publication No. 2006-325489
Patent document 2: japanese patent laid-open publication No. 2019-208915
Disclosure of Invention
Problems to be solved by the invention
The aerosol product for constant spraying of patent document 1 is a product that improves the efficiency of pest control by increasing the spraying force, but such an aerosol product for constant spraying having a strong spraying force is not necessarily a formulation design suitable for use in a narrow space such as a bathroom or a toilet.
The metered-dose aerosol product of patent document 2 exhibits a sufficient deodorizing effect not only on a space but also on a floor, but is not necessarily suitable for controlling harmful microorganisms in a narrow space such as a bathroom or a toilet because of problems such as generation or propagation of harmful microorganisms such as mold and bacteria in a ceiling or a wall that is difficult to clean.
As described above, although various developments have been made on the metered-dose aerosol products for the purpose of killing insects, deodorizing, and the like, it is difficult to develop metered-dose aerosol products in which harmful microorganisms such as mold, bacteria, and virus, indoor dust, and harmful fine substances such as PM2.5 are targeted for control, and they have not yet been put into practical use.
In particular, in the control of harmful microorganisms such as mold in a bathroom, it has been common to use (1) fumigants or (2) full-volume aerosol sprays. These preparations prevent the generation of harmful microorganisms such as mold in a certain period after use by one-time treatment, but it is necessary to discard the fumigant or the entire amount of spray-type aerosol used each time, which is labor-consuming and time-consuming. Further, if the place of use cannot be completely sealed, part of the smoke or the medicine may leak into another room during use. Therefore, there is a demand for the development of a metered-dose aerosol product which can control harmful microorganisms such as mold by a simpler operation than (1) fumigant or (2) full-dose aerosol.
The present invention has been made in view of the above problems, and an object of the present invention is to provide: a specific-pest-control metered-dose aerosol product which can exert an excellent control effect on a specific pest including a harmful microorganism and/or a harmful fine substance in a space (particularly a narrow space) by uniformly adhering a sufficient amount of a control component to a ceiling or a wall; and a method for controlling a specific harmful substance using the product.
Means for solving the problems
The metered-dose aerosol product for controlling specific noxious substances according to the present invention for solving the above problems is characterized in that,
which is a specific noxious substance control metered-dose aerosol product for controlling a specific noxious substance containing a noxious microorganism and/or a noxious fine substance in a space,
the aerosol product for controlling specific harmful substances is obtained by filling an aerosol container having a constant injection valve with an aerosol liquid containing a specific harmful substance controlling component and an organic solvent and a propellant,
the specific gravity of the aerosol collagen liquid at 20 ℃ is 0.76-0.95,
the internal pressure of the aerosol container is set to 0.60MPa or less at 25 ℃.
The aerosol product for controlling a specific noxious substance according to the present invention is an aerosol container provided with a quantitative injection valve, and is filled with an aerosol liquid containing a specific noxious substance-controlling component and an organic solvent, and a propellant, wherein the aerosol liquid has a specific gravity at 20 ℃ and an internal pressure at 25 ℃ in the above-described ranges, so that when the aerosol product for controlling a specific noxious substance is injected into a space, the injected particles do not remain in the air excessively, and a sufficient amount of the controlling component is uniformly adhered to a ceiling or a wall surface. Harmful microorganisms such as mold and bacteria tend to be generated in large quantities and propagate on the ceiling and wall surfaces which are difficult to clean, and even harmful fine substances such as indoor dust are easily attached to the ceiling and wall surfaces, so that the specific harmful substances containing the harmful microorganisms and/or the harmful fine substances can be effectively prevented and removed in the space by the sufficient amount of the control components uniformly attached to the ceiling and wall surfaces.
In the metered-dose aerosol product for controlling a specific noxious substance according to the present invention, it is preferable that the aerosol container has a volume ratio (a/b) of the aerosol liquid (a) to the propellant (b) set to 1/99 to 70/30 in terms of a volume ratio.
According to the metered dose aerosol product for controlling a specific noxious substance of the present configuration, when the metered dose aerosol product for controlling a specific noxious substance is sprayed into a space with the capacity ratio (a/b) in the above range, a sufficient amount of the control component is uniformly adhered to the ceiling or the wall surface without leaving the sprayed particles excessively in the air, and an excellent control effect can be exerted on the specific noxious substances including harmful microorganisms and/or harmful fine substances.
In the metered-dose aerosol for controlling a specific noxious substance according to the present invention,
preferably, the organic solvent is at least one selected from the group consisting of a lower alcohol having 2 to 3 carbon atoms, a higher fatty acid ester having 16 to 20 carbon atoms, and a hydrocarbon solvent.
According to the metered-dose aerosol product for controlling a specific noxious substance of the present configuration, by using at least one selected from the group consisting of a lower alcohol having 2 to 3 carbon atoms, a higher fatty acid ester having 16 to 20 carbon atoms, and a hydrocarbon solvent as an organic solvent, a sufficient amount of a control component is uniformly adhered to a ceiling or a wall surface without leaving the sprayed particles excessively in the air, and an excellent control effect can be exerted on the specific noxious substance including harmful microorganisms and/or harmful fine substances.
In the metered-dose aerosol for controlling a specific noxious substance according to the present invention,
preferably, the propellant is liquefied petroleum gas and/or hydrofluoroolefin.
According to the metered-dose aerosol product for controlling a specific noxious substance of the present configuration, by using liquefied petroleum gas and/or hydrofluoroolefin as a propellant, a sufficient amount of a control component can be uniformly adhered to a ceiling or a wall surface without leaving an excessive amount of sprayed particles in the air, and an excellent control effect can be exerted on a specific noxious substance containing a noxious microorganism and/or a noxious fine substance.
In the metered-dose aerosol for controlling a specific noxious substance according to the present invention,
preferably, the volume of the space is 2.0 to 18.8m 3 In a narrow space.
The aerosol product for controlling specific noxious substances with a constant volume is characterized in that the volume of the space is 2.0 to 18.8m 3 In a narrow space, the volume of the aerosol product for controlling specific harmful substances is 2.0 to 18.8m 3 When the spraying is performed in a narrow space, the sprayed particles are not excessively left in the air, and a sufficient amount of the control component is uniformly adhered to the ceiling or the wall surface. Harmful microorganisms such as mold and bacteria tend to be generated in large quantities and propagate on ceilings and walls which are difficult to clean, and even harmful fine substances such as indoor dust are easily attached to ceilings and walls, so that by a sufficient amount of the control components uniformly attached to ceilings and walls, excellent control effects can be exerted on specific harmful substances including harmful microorganisms and/or harmful fine substances in a narrow space.
In the metered-dose aerosol for controlling a specific noxious substance according to the present invention,
preferably, the amount of the specific pest control component released is set to 0.01 to 250mg/m 3 。
According to the metered-dose aerosol product for controlling specific noxious substances of the present configuration, by setting the release amount of the specific noxious substance-controlling component contained in the metered-dose aerosol product for controlling specific noxious substances to the above range, when the metered-dose aerosol product for controlling specific noxious substances is ejected into a space, a sufficient amount of the controlling component is uniformly adhered to a ceiling or a wall surface without excessive remaining of the ejected particles in the air, and an excellent controlling effect can be exerted on specific noxious substances including harmful microorganisms and/or harmful fine substances.
The method for controlling a specific noxious substance according to the present invention for solving the above problems is characterized in that,
which is a method for controlling a specific noxious substance by spraying the aerosol product for controlling a specific noxious substance by using the above-mentioned fixed-amount spray aerosol product,
the aerosol product for controlling the specific noxious substances is sprayed toward a space indoors.
According to the specific noxious substance control method of the present configuration, by a simple operation of spraying only the aerosol product for controlling the specific noxious substance toward the space indoors by a fixed amount, a sufficient amount of the control component is uniformly adhered to the ceiling or the wall surface without leaving the sprayed particles excessively in the air. Harmful microorganisms such as mold and bacteria tend to be generated in large quantities and propagate on the ceiling and wall surfaces which are difficult to clean, and even harmful fine substances such as indoor dust are easily attached to the ceiling and wall surfaces, so that the specific harmful substances containing the harmful microorganisms and/or the harmful fine substances can be effectively prevented and removed in the space by the sufficient amount of the control components uniformly attached to the ceiling and wall surfaces.
In the method for controlling a specific noxious agent according to the present invention,
preferably, the volume of the space is 2.0 to 18.8m 3 In a narrow space.
The method for controlling specific harmful substances according to the constitution, especially the volume of the space is 2.0-18.8 m 3 When a predetermined amount of the aerosol product for controlling a specific harmful substance is sprayed in a narrow space, a sufficient amount of the control component is uniformly adhered to a ceiling or a wall surface without leaving an excessive amount of the sprayed particles in the air, and an excellent control effect can be exerted on the specific harmful substance including a harmful microorganism and/or a harmful fine substance.
In the method for controlling a specific noxious agent according to the present invention,
preferably, the amount of the specific pest control component released is 0.01 to 250mg/m 3 The method (2) is to spray the specific noxious substance control quantitative spray aerosol product.
According to the specific noxious substance control method of the present configuration, by setting the amount of the specific noxious substance control component released from the metered-dose aerosol product for controlling specific noxious substances to the above range, when the metered-dose aerosol product for controlling specific noxious substances is sprayed into a space, sufficient amounts of the control component are uniformly adhered to the ceiling or wall surface without leaving the sprayed particles in the air excessively, and an excellent control effect can be exerted on specific noxious substances including harmful microorganisms and/or harmful fine substances.
Detailed Description
Hereinafter, the metered-dose aerosol for controlling a specific noxious substance and the method for controlling a specific noxious substance according to the present invention will be described. However, the present invention is not intended to be limited to the configurations described below.
[ quantitative spray aerosol product for controlling specific harmful substances ]
The aerosol product for controlling a specific noxious substance of the present invention is a constant-volume-spraying type aerosol used for controlling a specific noxious substance including a harmful microorganism and/or a harmful fine substance in a space (particularly a narrow space), and is configured by filling an aerosol liquid containing a specific noxious substance controlling component and a solvent, and a propellant in an aerosol container provided with a constant-volume-spraying valve. Here, the "harmful microorganism" refers to a biological or biologically derived substance such as bacteria, mold, virus, mite, pollen, and the like, and the "harmful fine substance" refers to a non-biological or non-biological derived substance such as indoor dust, PM2.5, yellow sand, and the like. In this specification, the term "harmful microorganism" and the term "harmful fine substance" are collectively referred to as "specific harmful substance". In addition, the "space" in the present invention is less than 2.0m 3 A gap space of 2.0 to 18.8m 3 The volume of a room with a narrow space, which is equivalent to 4.5 to 8 tatami, is 18.8 to 33.3m 3 Degree (area 7.5-13.3 m) 2 Height of 2.2 to 3.0m) and a volume of a room equivalent to 8 to 16 tatami of 33.3 to 66.6m 3 Degree (area 13.3-26.6 m) 2 And a height of 2.2 to 3.0m), and the like, without particular limitation. The volume of the "narrow space" assumed to be 2.0 to 18.8m for the metered-dose aerosol product for controlling a specific noxious substance of the present invention to exhibit a particularly excellent effect 3 Examples of the left and right spaces include a bathroom, a locker room, a toilet room,A closed or semi-closed space such as a toilet, closet, wardrobe, automobile, tent, warehouse, storehouse, garage, vestibule, etc. More specifically, for example, the volume is 2.0 to 3.0m 3 The small space (2) may be a toilet or the like, and has a volume of 3.0 to 18.8m 3 The narrow space may be a bathroom, for example. The aerosol product for controlling a specific noxious substance of the present invention is an aerosol of a constant-volume-spraying type, and therefore, the amount of chemicals sprayed is small, and by appropriately setting the specific gravity of the aerosol liquid at 20 ℃ and the internal pressure of the aerosol container at 25 ℃, an excellent control effect on a specific noxious substance containing a noxious microorganism and/or a noxious fine substance in a space (particularly a narrow space) is achieved. In the present specification, the effect of preventing propagation of harmful microorganisms is referred to as a control effect together with the effect of preventing propagation, because the harmful microorganisms are killed in addition to the effect of preventing propagation by forming an environment in which the harmful microorganisms are difficult to grow or exist. For example, when a mold is a control target, the mold-controlling effect and the fungicidal effect are included in the control effect. In addition, the harmful fine substances are also referred to as a control effect together with the pollution prevention effect because the harmful fine substances are removed in addition to the pollution prevention effect resulting from the environment in which the harmful fine substances are difficult to adhere to walls and the like. For example, when indoor dust is a control target, the dust control effect and the dust removal effect are included in the control effect.
< Aerosol collagen liquid >
Examples of the specific noxious substance control component, which is one of the main components of the aerosol liquid, include a bacteria control component, a mold control component, a virus control component, an allergen control component, and the like. The above-mentioned specific noxious substance controlling components may be used singly or in combination of plural kinds. In the specific pest control component, when an optical isomer based on an asymmetric carbon or a geometric isomer based on a double bond is present, any one or an arbitrary mixture thereof is also included in the present invention.
The bacteria control component is not particularly limited, but includes: isopropyl methylphenol (IPMP), carvacrol, thymol, Triclosan (Triclosan), methylparaben (Paraben), ethylparaben, propylparaben, butylparaben, 4-chloro-3, 5-dimethylphenol, orthophenylphenol, o-cresol, m-cresol, and p-cresol, Benzalkonium chloride (Benzalkonium chloride), Benzalkonium chloride (Japanese: ベンザルコニウム) methylsulfate, Benzalkonium salts such as Benzalkonium salts of organic acids, Benzethonium chloride (Benzethonium chloride), Benzethonium chloride (Japanese: ベンゼトニウム) methylsulfate, Benzethonium salts such as Benzethonium salts of organic acids, Cetylpyridinium chloride (Cetylpyridinium chloride), Cetylpyridinium chloride (Japanese: セチルピリジニウム) methylsulfate, Cetylpyridinium salts of organic acids, and the like Cetylpyridinium salts, Cationic surfactant-based bacterial components such as didecyldimethylammonium chloride, didecyldimethylammonium methylsulfate and the like, dilauryldimethylammonium salts such as dilauryldimethylammonium chloride, dilauryldimethylammonium methylsulfate and the like, distearyldimethylammonium salts such as distearyldimethylammonium chloride, distearyldimethylammonium methylsulfate and the like, and 1, 4-bis [3,3 '- (1-decylpyridinium) methoxy ] dibromobutane, 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] dichlorobutane, 1, 4-bis [3,3 '- (1-decylpyridinium) methoxy ] butane dimethylsulfate and the like, such as 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] butane salts and the like, and the like, Biguanide (biguanidine) -based bacterial control components, azole-based bacterial control components such as Tebuconazole and Enilconazole (Enilconazole), grapefruit seed extract, persimmon seed extract and grape seed extract, fruit seed extract-based bacterial control components such as glycerol monolaurate (Monolaurin), glycerol Monocaprin (Monocaprin) and glycerol Monocaprylin (Monocaprin), chlorhexidine digluconate, chlorhexidine hydrochloride, chlorhexidine-based bacterial control components such as chlorhexidine, octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl diisopropyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, and mixtures thereof, Silicon-based bacterial control components such as tetradecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyldin-propyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyldimethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyldin-propyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldimethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldi-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, and the like, Carboxylic acid-based bacteria-controlling components such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyldiethylaminoglycine, polylysine, or salts thereof, silver-based bacteria-controlling components such as dehydroacetic acid, Chloramine (Chloramine), 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, silver zeolite, Zinc pyrithione (Zinc pyrithione), thiamine dilauryl sulfate (japanese: チアミンラウリル sulfuric acid salt), protamine, hydroxyalkylchitosan, or salts thereof. Among these bacteria control components, isopropyl methylphenol (IPMP), carvacrol, thymol, benzalkonium chloride, 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] dibromobutane, glycerol monocaprate, glycerol monocaprylate, and tebuconazole are preferable.
The mold control component is not particularly limited, but includes: phenol-based mold control components such as isopropyl methylphenol (IPMP), carvacrol, thymol, triclosan, methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate, 4-chloro-3, 5-dimethylphenol, o-phenylphenol, o-cresol, m-cresol, and p-cresol, benzalkonium chloride, benzalkonium methyl sulfate, benzalkonium organic acid salts such as benzalkonium chloride, benzethonium methyl sulfate, and benzethonium organic acid salts, cetylpyridinium chloride, cetylpyridinium methyl sulfate, cetylpyridinium organic acid salts such as cetylpyridinium salts, didecyldimethylammonium chloride, didecyldimethylammonium methyl sulfate such as didecyldimethylammonium chloride, dilauryldimethylammonium methyl sulfate, and the like, cetylpyridinium salts such as didecyldimethylammonium chloride, and the like, A mold control component of a cationic surfactant system such as distearyldimethylammonium salt such as distearyldimethylammonium chloride or distearyldimethylammonium methylsulfate, and a mold control component of a fruit extract system such as 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] dibromobutane, 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] dichlorobutane or 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] butane dimethylsulfate, a biguanide-based mold component, a tebuconazole or enoconazole, a grapefruit seed extract, a persimmon seed extract or a grape seed extract, a mold control component of a fruit extract system such as a grapefruit seed extract or a grape seed extract, Glycerin mono fatty acid ester type fungus control components such as glycerin monolaurate, glycerin monocaprate, glycerin monocaprylate, etc., chlorhexidine salts such as chlorhexidine digluconate, chlorhexidine hydrochloride, etc., chlorhexidine-based fungus control components such as chlorhexidine, octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl diisopropyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, etc, Pentadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyldin-propyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldimethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldi-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, and other silicon-based mold control components, benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyldiethylaminoglycine, polylysine, and other carboxylic acid-based mold control components or salts thereof, a mold control agent, and a mold control agent, a mold control, Silver-based mold control ingredients such as dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, and silver zeolite, zinc pyrithione, thiamine dilauryl sulfate, protamine, hydroxyalkylchitosan or salts thereof, and antifungal perfumes. Among these mold control components, isopropyl methylphenol (IPMP), carvacrol, thymol, benzalkonium chloride, 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] dibromobutane, glycerol monocaprate, glycerol monocaprylate, and tebuconazole are preferable.
The virus control component is not particularly limited, but includes: phenol-based virus control components such as isopropyl methylphenol (IPMP), carvacrol, thymol, triclosan, methyl p-hydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate, butyl p-hydroxybenzoate, 4-chloro-3, 5-dimethylphenol, o-phenylphenol, o-cresol, m-cresol, and p-cresol, benzalkonium chloride, benzalkonium methyl sulfate, benzalkonium salts such as benzalkonium salts of organic acids, benzethonium salts such as benzethonium chloride, benzethonium methyl sulfate, and benzethonium salts of organic acids, cetylpyridinium chloride, cetylpyridinium methyl sulfate, cetylpyridinium salts such as organic acid salts of cetylpyridinium, didecyldimethylammonium chloride, didecyldimethylammonium methyl sulfate such as didecyldimethylammonium sulfate, dilauryldimethylammonium chloride, dilauryldimethylammonium methyl sulfate, and the like, cetyl pyridinium salts such as didecyldimethylammonium chloride, and the like, A cationic surfactant-based virus-controlling component such as a distearyldimethylammonium salt such as distearyldimethylammonium chloride or distearyldimethylammonium methylsulfate, and a 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] dibromobutane or a 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] dichlorobutane salt such as 1, 4-bis [3,3 ' - (1-decylpyridinium) methoxy ] butane dimethylsulfate, a biguanide-based virus-controlling component, an azole-based virus-controlling component such as tebuconazole or eniconazole, a grapefruit seed extract, a persimmon seed extract, a grape seed extract-based virus-controlling component such as a grapefruit seed extract, a grape seed extract, a vitamin C-based virus-controlling component such as a vitamin A, a derivative, glycerol monofatty acid ester virus control components such as glycerol monolaurate, glycerol monocaprate and glycerol monocaprylate, chlorhexidine salts such as chlorhexidine digluconate and chlorhexidine hydrochloride, chlorhexidine virus control components such as chlorhexidine, octadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, dodecyl diisopropyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, tetradecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyl dimethyl (3-triethoxysilylpropyl) ammonium chloride, and mixtures thereof, Silicon-based virus-controlling components such as pentadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, pentadecyldin-propyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldimethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldiethyl (3-triethoxysilylpropyl) ammonium chloride, hexadecyldi-n-propyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl diethyl (3-triethoxysilylpropyl) ammonium chloride, octadecyl di-n-propyl (3-triethoxysilylpropyl) ammonium chloride, etc., carboxylic virus-controlling components such as benzoic acid, salicylic acid, sorbic acid, ethylenediaminetetraacetic acid (EDTA), glycine, alkyldiethylaminoglycine, polylysine, etc., or salts thereof, Dehydroacetic acid, chloramine, 3-iodo-2-propyl-N-butylcarbamate (IPBC), phenoxyethanol, silver-based virus control components such as silver zeolite, zinc pyrithione, thiamine dilauryl sulfate, protamine, hydroxyalkylchitosan or salts thereof, and the like. Among these virus control components, isopropyl methylphenol (IPMP), carvacrol, thymol, benzalkonium chloride, 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] dibromobutane, glycerol monocaprate, glycerol monocaprylate, and tebuconazole are preferable.
The allergen-controlling component is not particularly limited, but examples thereof include mite-controlling components, pollen-controlling components, house dust-controlling components, and the like, and examples thereof include: sulfamite (Amidoflumet), benzyl benzoate, phenyl salicylate, benzyl salicylate, cyclohexyl salicylate, dibutyl sebacate, dipropyl sebacate, dibutyl adipate, diethyl phthalate, dipropyl phthalate, dibutyl phthalate, p-menthane-3, 8-diol (PMD), 3-iodo-2-propynyl butyl carbamate (IPBC), Phenothrin (Phenotrin), Ecagrelin (Icaridin), butyl acetyl ethyl aminopropionate (IR3535), and culicin (DEET). Examples of the pollen control component and the house dust control component include: poly 2- (meth) acryloyloxyalkylphosphocholine (Phosphocholine), 2- (meth) acryloyloxyalkylphosphocholine- (meth) acrylic acid copolymer, 2- (meth) acryloyloxyalkylphosphocholine- (meth) acrylic acid alkyl ester copolymer, 2- (meth) acryloyloxyalkylphosphocholine-1- (meth) acryloyloxy 2-hydroxyalkyl 3-trialkylammonium copolymer, N- (meth) acryloyloxyalkyl N, N-dialkylammonium-alpha-N- (alkyl) carboxybetaine-alkyl (meth) acrylate copolymer, N-Phosphocholine-N' -alkylenedioxy-bis-alkylacrylamide -N-isoalkylacrylamide copolymers, poly N, N-di (alkyl) ammonium- α -N-alkylsulfobetaine (meth) acrylic acid, hydroxyalkylchitosans or salts thereof, titanium oxide, and the like.
The content of the specific harmful substance control component in the aerosol collagen liquid is preferably 0.01 to 70 w/v%, more preferably 0.05 to 50 w/v%, and still more preferably 0.1 to 40 w/v%. When the content of the specific harmful substance control component in the aerosol collagen liquid is in the range of 0.01 to 70 w/v%, a sufficient amount of the control component is uniformly adhered to a ceiling or a wall surface when the aerosol is sprayed in a space (particularly a narrow space), and thus an appropriate control effect against the specific harmful substance including harmful microorganisms and/or harmful fine substances can be obtained.
Examples of the organic solvent as one of the main components of the aerosol collagen liquid include: lower alcohols having 2 to 3 carbon atoms such as ethanol and isopropyl alcohol (IPA), hydrocarbon solvents such as n-paraffin and isoparaffin, higher fatty acid esters having 16 to 20 carbon atoms such as isopropyl myristate (IPM), glycol ether solvents having 3 to 10 carbon atoms, and ketone solvents. Among these, in order to obtain an excellent control effect against a specific harmful substance including a harmful microorganism and/or a harmful fine substance by uniformly adhering a sufficient amount of a control component to a ceiling or a wall surface without excessively remaining particles in the air, a lower alcohol having 2 to 3 carbon atoms, a hydrocarbon-based solvent, and a higher fatty acid ester having 16 to 20 carbon atoms are preferable, and a lower alcohol having 2 to 3 carbon atoms, which has a bacterium control effect, a virus control effect, and the like, is more preferably used even when an organic solvent itself is used. The organic solvent may be used alone or in combination of two or more, but from the viewpoint of simplification of the production process, it is preferable to use only one kind of component. In addition to the organic solvent, an aqueous solvent such as water may be mixed.
The specific gravity of the aerosol collagen liquid at 20 ℃ is set to 0.76 to 0.95, preferably 0.76 to 0.90, and more preferably 0.76 to 0.88. The specific gravity of the aerosol collagen liquid at 20 ℃ is an important factor related to the sedimentation of the sprayed particles, and if the specific gravity of the aerosol collagen liquid at 20 ℃ is 0.76 to 0.95, a sufficient amount of the control component after spraying can be uniformly adhered to a ceiling or a wall surface in a space (particularly a narrow space). Harmful microorganisms such as mold and bacteria tend to be generated and propagated in large quantities on ceilings, wall surfaces and the like which are difficult to clean, and even for harmful fine substances such as indoor dust, since the harmful fine substances are easily attached to ceilings and wall surfaces, by a sufficient amount of the control components uniformly attached to ceilings and wall surfaces, excellent control effects can be exerted on specific harmful substances including harmful microorganisms and/or harmful fine substances in a space (particularly a narrow space).
In addition to the above components, an insecticidal component, a repellent, a fragrance, a deodorant, a stabilizer, an antistatic agent, an antifoaming agent, an excipient, and the like may be appropriately blended in the aerosol stock solution without departing from the gist of the present invention. As the pesticidal component, there may be mentioned: transfluthrin, Metofluthrin, Profluthrin, cyclopentenyl-Allethrin, Furamethrin, Empenthrin, momfluthrin (CAS: 609346-29-4, Japanese モンフルオロトリン), Dimefluthrin, Permethrin, Meperfluthrin, Heptafluthrin, Phenothrin, Cyphenothrin, Cypermethrin, Cyfluthrin, Bifenthrin, Fenpropathrin, tetramethrin, Fenpropathrin, Tralomethrin, tetramethrin, Fenpropathrin, tetramethrin, and the like, Organophosphate compounds such as Dichlorvos and Fenitrothion, carbamate compounds such as Propoxur, Neonicotinoid compounds such as Dinotefuran, Imidacloprid and Clothianidin, Fipronil, Indoxacarb, flubendiamide and methoxazole. As the repellent, there may be mentioned: culicifumide (DEET), butyl acetyl amino ethyl propionate (IR3535), p-menthane-3, 8-diol, and escarodin (Icaridin), etc. Examples of the aromatic agent include: orange oil, lemon oil, lavender oil, peppermint oil, eucalyptus oil, lemon eucalyptus oil, citronella oil, lime oil, grapefruit oil, jasmine oil, juniper oil, green tea essential oil, peppermint oil, menthol, menthyl acetate, limonene, α -pinene, linalool, geraniol, phenylethyl alcohol, amyl cinnamic aldehyde, cuminaldehyde, terpineol, and benzyl acetate, and a perfume component to which a geraniol or geranial called "green-green" perfume is added. When the optical isomers based on asymmetric carbon and the geometric isomers based on double bonds of the respective components are present, they may be each or an arbitrary mixture thereof.
The metered-dose aerosol preparation for controlling a specific noxious substance of the present invention may be formulated into a water-based formulation. In this case, the amount of water contained in the aerosol raw liquid is preferably 5 to 80 v/v%, although not particularly limited, and a slight amount of a nonionic surfactant may be added as a solubilizing aid within a range that does not affect the ejection mode of the ejected particles. Examples of the nonionic surfactant include: ethers such as polyoxyethylene alkyl ethers, polyoxyethylene alkylphenyl ethers, polyoxyethylene polyoxypropylene alkyl ethers, and polyoxyethylene alkylamino ethers, fatty acid esters such as polyethylene glycol fatty acid esters, polyoxyethylene sorbitan fatty acid esters, and polyoxyethylene glycerin fatty acid esters, polyoxyethylene styrenated phenols, and polyalkanolamides of fatty acids, and the like.
< propellant >
The propellant used in the metered dose aerosol for controlling a specific noxious substance of the present invention is not particularly limited, but includes: liquefied gases such as Liquefied Petroleum Gas (LPG) such as propane and butane, liquefied gases such as n-pentane, isopentane, dimethyl ether (DME) and hydrofluoroolefin such as HFO1234ze, and compressed gases such as nitrogen, carbon dioxide, nitrous oxide and compressed air. The propellant may be used alone or in a mixed state, but in order that the propellant particles do not remain excessively in the air and that a sufficient amount of the control component is uniformly adhered to the ceiling or wall surface, the propellant preferably contains LPG or hydrofluoroolefin because the propellant can exert a more excellent control effect on a specific harmful substance including harmful microorganisms and/or harmful fine substances in a space (particularly a narrow space). The propellant is preferably used by adjusting the gauge pressure (20 ℃) to 0.10 to 0.70 MPa.
The aerosol container for the metered-dose spraying aerosol product for controlling a specific noxious substance of the present invention preferably has a volume ratio (a/b) of the aerosol liquid (a) to the propellant (b) of 1/99 to 70/30 in terms of a volume ratio, and is more preferably 10/90 to 60/40, and still more preferably 20/80 to 55/45, from the viewpoint of adhesion of the chemical to a ceiling or a wall surface. When the capacity ratio (a/b) is in the above range, the sprayed particles do not remain excessively in the air and adhere to the ceiling or the wall surface when the aerosol is sprayed in a space (particularly a narrow space), and therefore a sufficient amount of the specific noxious substance control component can be uniformly adhered to the ceiling or the wall surface. Thus, it is possible to obtain an appropriate control effect against a specific harmful substance including a harmful microorganism and/or a harmful fine substance, and to reduce a feeling of irritation to humans.
The aerosol container for the metered dose aerosol for controlling a specific noxious substance of the present invention has an internal pressure of 0.60MPa or less, preferably 0.10 to 0.60MPa, more preferably 0.20 to 0.60MPa, and still more preferably 0.30 to 0.50MPa at 25 ℃. When the internal pressure is 0.60MPa or less at 25 ℃, a sufficient amount of the specific noxious substance control component can be adhered to the ceiling or wall surface when the aerosol is sprayed in a space (particularly a narrow space). If the internal pressure exceeds 0.60MPa, the force of the ejection is too strong, and therefore, when the particles reach the wall surface, some of the ejected particles bounce back, and the uniformity of diffusion of the particles adhering to the ceiling or the wall surface may become insufficient. The internal pressure of such an aerosol product can be appropriately adjusted by the type of propellant, the vapor pressure of the propellant, and the like. The aerosol container may be a pressure-resistant container capable of withstanding an internal pressure of 0.60MPa, and examples of the material include metals such as aluminum and tin plating, synthetic resins such as polyethylene terephthalate, and pressure-resistant glass. In addition, when the material of the aerosol container is synthetic resin, it may be translucent or transparent. In the present embodiment, the internal pressure of the aerosol container for spraying the aerosol product with a fixed amount of the specific noxious substance control is measured by the following procedure.
(1) The aerosol product for controlling the specific noxious substances was immersed in a constant-temperature water bath at 25. + -. 0.5 ℃ for 30 minutes.
(2) Then, the specific noxious substance control metered dose aerosol product was set upright, and the valve stem (Japanese: ステム) of the aerosol container was airtightly inserted into the insertion port of the pressure gauge, and the measurement pressure was read to decimal point 2.
(3) The measurement was performed 1 time, and the measured value was not rounded up, but the read value was defined as the internal pressure value.
The specific noxious substance control metered dose aerosol product of the present invention preferably has a spraying force of 2.0 to 40.0gf, more preferably 2.0 to 35.0gf, even more preferably 3.0 to 30.0gf, and particularly preferably 5.0 to 20.0gf, at a distance of 15cm from the spraying opening. When the spraying force is in the above range, a sufficient amount of the specific noxious substance control component is uniformly adhered to the ceiling or the wall surface when the aerosol is sprayed in a space (particularly a narrow space), and a practically sufficient control effect for the specific noxious substances including harmful microorganisms and/or harmful fine substances is obtained. If the spraying force is less than 2.0gf, the spraying force may be insufficient, and the amount of the specific harmful control components adhering to the ceiling or wall surface may be insufficient, while if the spraying force exceeds 40.0gf, the spraying force is too strong, so that a part of the sprayed particles may rebound when reaching the wall surface, and the uniformity of diffusion in the ceiling or wall surface may be insufficient. Such ejection force can be appropriately adjusted by the composition of the aerosol liquid, the kind of the ejection agent, the internal pressure of the aerosol product, the size and shape of the ejection port, and the like. In the present embodiment, the jetting force of the aerosol product for quantitative jetting for controlling specific noxious substances was measured by a digital dynamometer (FGC-0.5, manufactured by shin-shogaku corporation).
The constant-volume-spraying aerosol product for controlling a specific noxious substance of the present invention is provided with a constant-volume-spraying valve for performing a constant-volume-spraying treatment in a space. The injection volume per one time of the constant injection valve is set to 0.08 to 3.0mL, preferably 0.08 to 2.0mL, more preferably 0.1 to 1.0mL, and further preferably 0.2 to 0.9 mL. When the ejection capacity per one time is within the above range, a sufficient amount of the specific harmful substance controlling component can be uniformly adhered to the ceiling or the wall surface, and an excellent controlling effect on the specific harmful substance including harmful microorganisms and/or harmful fine substances can be obtained.
The injection member (injection button) is attached to the aerosol container via a fixed-quantity injection valve. The injection member is provided with an injection port for injecting the aerosol raw liquid and the propellant taken from the aerosol container through the stem hole of the fixed injection valve. The diameter of the jet orifice of the jet member is preferably 0.2 to 1.0 mm. If the diameter of the ejection port is in the above range, the ejection force can be adjusted to an appropriate range. The shape (cross-sectional shape) of the ejection port is not particularly limited, but may be a polygon such as a circle or a quadrangle, an ellipse, or the like, and is preferably a circle. Here, the ejection opening diameter refers to the major axis of an ellipse when the ejection opening is in the shape of an ellipse, and refers to the diameter of a circumscribed circle of a polygon when the ejection opening is in the shape of a polygon.
With respect to the metered-dose aerosol formulation for controlling a specific noxious substance of the present invention, the amount of the specific noxious substance-controlling component released into the air is preferably set to 0.01 to 250mg/m 3 More preferably 0.025 to 125mg/m 3 . When the amount of the specific harmful substance control component released into the air is within the above range, the control effect on the specific harmful substance containing the harmful microorganism and/or the harmful fine substance is appropriately exerted in the space, and the specific harmful substance containing the harmful microorganism and/or the harmful fine substance can be reliably controlled. The aerosol product for controlling specific noxious substances of the present invention can be sprayed 1 time to give an air release of a specific noxious substance controlling component of 0.01 to 250mg/m 3 In the mode (1), the injection amount of the specific harmful-substance-controlling component is set, and the amount of the specific harmful-substance-controlling component released into the air may be 0.01 to 250mg/m by 2 or more injections 3 In the embodiment (1), the amount of the specific noxious substance control component sprayed per one time is set. From the viewpoint of enabling a sufficient amount of the specific pest control component to be uniformly adhered to the ceiling or wall surface and obtaining an excellent control effect on the specific pest containing harmful microorganisms and/or harmful fine substances, it is preferable that the amount of the specific pest control component released into the air is 0.01 to 250mg/m by spraying 2 or more times 3 The mode of (2). The amount of the specific noxious substance-controlling component to be released can be adjusted within the above-mentioned ranges, as appropriate, for example, by adjusting the composition of the aerosol liquid, the ratio (a/b) of the volumes of the aerosol raw liquid (a) and the propellant (b), and the volume of the metered dose injection valve to be injected per one time.
The metered-dose aerosol product for controlling a specific noxious substance according to the present invention can be applied usually 1 time, so that the space can be made an environment capable of controlling a specific noxious substance containing harmful microorganisms and/or harmful fine substances for about 7 to 14 days. The period of time in which a specific harmful substance including a harmful microorganism and/or a harmful fine substance can be controlled can be set to a period of less than 7 days or more than 14 days by adjusting the composition of the aerosol liquid, the kind of the propellant, the specific gravity of the aerosol liquid at 20 ℃, the internal pressure of the aerosol container, and the like.
< specific harmful substance >
As the specific harmful substances to be controlled in the present invention, examples of the harmful microorganisms include biological or biologically derived substances such as bacteria, mold, virus, mites, and pollen, and examples of the harmful fine substances include non-biological or non-biological substances such as house dust, PM2.5, and yellow sand. Allergens are contained in harmful microorganisms and harmful fine substances. The metered-dose aerosol product for controlling a specific noxious substance of the present invention can more effectively control bacteria and mold which tend to be generated in large quantities and propagated on ceilings and walls which are difficult to clean, among the specific noxious substances.
[ method for controlling specific noxious substances ]
The method for controlling specific noxious substances according to the present invention comprises spraying the aerosol product for controlling specific noxious substances in a fixed amount in an indoor space (preferably, with a volume of 2.0 to 18.8 m) 3 In a narrow space) is performed. When the method for controlling a specific harmful substance of the present invention is carried out, a sufficient amount of a control component is uniformly adhered to a ceiling or a wall in a space (particularly, a narrow space), and an excellent control effect is exerted on the specific harmful substance including a harmful microorganism and/or a harmful fine substance. Here, the amount of the specific noxious substance-controlling aerosol product to be sprayed is preferably 0.01 to 250mg/m in terms of the amount of the specific noxious substance-controlling component released into the air 3 More preferably, the concentration of the compound (D) is adjusted to 0.025 to 125mg/m 3 Is adjusted. When the amount of the specific noxious substance control component released is within the above range, the harmful microorganisms and/or the harmful substances may be contained in the compositionThe specific harmful substances such as harmful fine substances exert more excellent control effects.
Examples
In order to verify the effect of the aerosol product for controlling a specific noxious substance of the present invention, aerosol products for controlling a specific noxious substance having the characteristic configuration of the present invention were prepared (examples 1 to 16), (1) tests for evaluating the ceiling/wall surface adhesiveness and the diffusion uniformity of the specific noxious substance control component were performed.
For comparison, metered-dose aerosol products not having the characteristic configuration of the present invention (comparative examples 1 to 3) were prepared and subjected to the same test. Further, the aerosol products for controlling specific noxious substances of examples 1,4, 8, 14 and 15 were used in a fixed-amount spray manner, and (2) tests for evaluating the use in a bathroom were carried out.
[ example 1]
Isopropyl methyl phenol (IPMP) (15 w/v%) as a specific harmful substance control component was dissolved in ethanol as an organic solvent to prepare an aerosol stock solution. The aerosol stock solution had a specific gravity of 0.82 at 20 ℃. An aerosol container (pressure-resistant container) equipped with a quantitative spray valve having a spray capacity of 0.4mL was pressurized and filled with 12mL of an aerosol liquid (a) and 18mL of a liquefied petroleum gas (b) as a propellant so that the volume ratio (a/b) was 40/60, thereby obtaining a quantitative spray aerosol product for controlling a specific noxious substance of example 1. The internal pressure of the aerosol product for controlling specific noxious substances sprayed at 25 ℃ was 0.45MPa, and the amount of the specific noxious substance controlling component sprayed per one time was 24 mg. The ejection force at an ejection distance of 15cm was 6.5 gf.
Comparative example 1
Isopropyl methylphenol (IPMP) (15 w/v%) as a control component was dissolved in ethanol as an organic solvent to prepare 30mL of an aerosol stock solution. The aerosol stock solution had a specific gravity of 0.82 at 20 ℃. This aerosol raw liquid was put into a container equipped with a pump jet head having a jet volume of 0.2mL for 1 time, to obtain a pump jet product of comparative example 1. The amount of the control component sprayed per one spray of the pump spray product was 30 mg. The ejection force at an ejection distance of 15cm was 2.0 gf.
Examples 2 to 16 and comparative examples 2 to 3
By following the procedure of example 1, various aerosol articles shown in table 1 were prepared. In the aerosol container with the constant-volume injection valve having an injection capacity of 0.2mL for the specific noxious substance-controlling constant-volume injection aerosol product of example 8, the specific noxious substance-controlling constant-volume injection aerosol products of examples 1,3, 4, 6, 9, 11 to 13 and 16, and the constant-volume injection aerosol products of comparative examples 2 to 3, the aerosol container with the constant-volume injection valve having an injection capacity of 0.4mL for 1 time, and the specific noxious substance-controlling constant-volume injection aerosol products of examples 2, 5, 7, 10, 14 and 15, the aerosol container with the constant-volume injection valve having an injection capacity of 1.0mL for 1 time were used.
[ Table 1]
In table 1 above, IPMP represents isopropylmethylphenol, compound a represents 1, 4-bis [3, 3' - (1-decylpyridinium) methoxy ] dibromobutane, IPBC represents 3-iodo-2-propyl-N-butylcarbamate, IPA represents isopropyl alcohol, IPM represents isopropyl myristate, LPG represents liquefied petroleum gas, HFO1234ze represents trans-1, 3,3, 3-tetrafluoropropane. The specific gravity (20 ℃ C.) of each component was IPMP: 0.97, thymol: 0.97, benzalkonium chloride 10% aqueous solution: 0.98, tebuconazole: 1.25, glyceryl monocaprylate: 0.99, glycerol monocaprate: 0.99, IPBC: 1.61, ethanol: 0.79, IPA: 0.79, Neo-chiozol: 0.76, IPM: 0.86, hexyl laurate: 0.86.
tests for evaluating ceiling/wall adhesion and diffusion uniformity of a specific pest control component were performed on examples 1 to 16 and comparative examples 1 to 3 (1). The test results are shown in table 2.
(1) Ceiling/wall adhesion and diffusion uniformity of specific noxious substance control component
In a closed volume of 4.2m 3 Glass plates of 20cm × 20cm were installed on the floor 6, ceiling 2 and wall 4 of the small room (width 1.8m, depth 1.3m and height 1.8 m). The aerosol product to be tested was sprayed from a height of 1m from the floor toward the center of the space 2 times in a slightly obliquely upward direction while standing at one of 4 corners of the small room. After 20 minutes passed from the spraying, the glass plate installed on the floor, the glass plate installed on the ceiling, and the glass plate installed on the wall were taken out, and the adhered specific noxious substance control components were washed out with acetone and analyzed by gas chromatography. Based on the obtained analysis values, the ratio of the amount of the control component adhering to the ceiling and the wall surface to the amount of the control component adhering to the floor surface was determined 20 minutes after the spraying treatment, and the ceiling and wall surface adhesiveness was evaluated. The evaluation results are expressed in 3 stages of A, B, C in order from the one with good ceiling and wall adhesion. Further, the diffusion uniformity was evaluated from the amount of control components attached to the ceiling and the wall, respectively. The evaluation results are expressed as 3 stages of A, B, C in order from the one with good diffusion uniformity.
[ Table 2]
As a result of the test, the ceiling and wall surface adhesion of the specific noxious substance control component was good, which was lower than that of the specific noxious substance control metered dose aerosol products of examples 1 to 16. Among them, examples 1,3 to 10, 12 to 15 having a specific gravity of 0.76 to 0.88 at 20 ℃ are more excellent not only in the ceiling and wall surface adhesion of the specific noxious substance control component but also in the diffusion uniformity. From this, it was found that the aerosol product for controlling a specific noxious substance according to the present invention was sprayed with a constant amount to confirm the control effect on the specific noxious substance containing harmful microorganisms and/or harmful fine substances in a space.
On the other hand, the pump spray product of comparative example 1 and the constant-volume spray aerosol product of comparative example 3 in which the specific gravity of the aerosol liquid at 20 ℃ exceeds 0.95 had low ceiling/wall adhesion of the control component. It is thus assumed that: the pump spray product of comparative example 1 and the metered dose aerosol product of comparative example 3 are not sufficient in the effect of controlling a specific harmful substance containing a harmful microorganism and/or a harmful fine substance in a space.
The aerosol product of comparative example 2, in which the internal pressure at 25 ℃ exceeded 0.60MPa, was not sufficient in terms of uniformity of diffusion to the ceiling and wall surface.
(2) Use in a bathroom
[ test example 1]
In a volume of 4m 3 (area 2m) 2 Height 2m), the specific noxious substance control metered-dose aerosol product of example 1 was sprayed 4 times from the inlet. After 14 days, it was confirmed that pink slime (Japanese: ヌメリ) (bacteria) or black mold (mold) was not produced in the bathroom. That is, pink slime (bacteria) or black mold (mold) can be controlled over 14 days. Further, no irritation such as choking is felt during the spraying operation in the bathroom.
[ test example 2]
In a volume of 4m 3 (area 2m) 2 Height 2m), the specific noxious substance control metered dose aerosol preparation of example 4 was sprayed from the inlet 2 times. After 14 days, it was confirmed that pink slime (bacteria) or black mold (mold) was not produced in the bathroom. That is, pink slime (bacteria) or black mold (mold) can be controlled over 14 days. Further, no irritation such as choking is felt during the spraying operation in the bathroom.
[ test example 3]
In a volume of 4m 3 (area 2m) 2 Height 2m), the specific noxious substance control metered dose aerosol product of example 8 was sprayed from the inlet 2 times. After 7 days, it was confirmed that pink slime (bacteria) or black mold (mold) was not produced in the bathroom. That is, pink mucus (thin) can be achieved in more than 7 daysBacteria) or black mold (mold). Further, no irritation such as choking was felt during the spraying operation in the bathroom.
[ test example 4]
In a volume of 4m 3 (area 2m) 2 Height 2m), the specific noxious substance controlling metered dose aerosol product of example 14 was sprayed 4 times from the inlet. After 7 days, it was confirmed that pink slime (bacteria) or black mold (mold) was not produced in the bathroom. That is, pink slime (bacteria) or black mold (mold) can be controlled over 7 days. Further, no irritation such as choking was felt during the spraying operation in the bathroom.
[ test example 5]
In a volume of 4m 3 (area 2m) 2 Height 2m), the specific noxious substance control metered dose aerosol production of example 15 was sprayed from the inlet 4 times. After 14 days, it was confirmed that pink slime (bacteria) or black mold (mold) was not produced in the bathroom. That is, pink slime (bacteria) or black mold (mold) can be controlled over 14 days. Further, no irritation such as choking was felt during the spraying operation in the bathroom.
Industrial applicability
The metered-dose aerosol product for controlling a specific noxious substance and the method for controlling a specific noxious substance according to the present invention can be used for the purpose of controlling a specific noxious substance containing a harmful microorganism and/or a harmful fine substance in a space, particularly a narrow space such as a bathroom or a toilet.
Claims (9)
1. A specific noxious substance control metered-dose aerosol product for controlling a specific noxious substance containing a harmful microorganism and/or a harmful fine substance in a space,
the aerosol product for controlling the specific harmful substance is formed by filling aerosol liquid containing the specific harmful substance control component and organic solvent and propellant into an aerosol container with a quantitative injection valve,
the specific gravity of the aerosol collagen liquid at 20 ℃ is 0.76-0.95,
the internal pressure of the aerosol container is set to 0.60MPa or less at 25 ℃.
2. The metered-dose aerosol for controlling a specific noxious substance according to claim 1, wherein a volume ratio a/b of the aerosol liquid a to the propellant b in the aerosol container is 1/99 to 70/30 in terms of a volume ratio.
3. The metered-dose aerosol product for controlling specific noxious substances according to claim 1 or 2, wherein the organic solvent is at least one selected from the group consisting of a lower alcohol having 2 to 3 carbon atoms, a higher fatty acid ester having 16 to 20 carbon atoms, and a hydrocarbon solvent.
4. The metered-dose aerosol for controlling a specific noxious substance according to any one of claims 1 to 3, wherein the propellant is liquefied petroleum gas and/or hydrofluoroolefin.
5. The metered-dose aerosol for controlling specific noxious substances according to any one of claims 1 to 4, wherein the space has a volume of 2.0m 3 ～18.8m 3 In a narrow space.
6. The metered-dose aerosol control product for controlling a specific noxious substance according to any one of claims 1 to 5, wherein the amount of the specific noxious substance-controlling component released is set to 0.01mg/m 3 ～250mg/m 3 。
7. A method for controlling a specific noxious substance, which comprises spraying the specific noxious substance-controlling aerosol product for controlling a specific noxious substance according to any one of claims 1 to 6,
the aerosol product for controlling the specific noxious substances is sprayed toward a space indoors.
8. The method for controlling specific pests according to claim 7, wherein the space has a volume of 2.0m 3 ～18.8m 3 In a narrow space.
9. The method for controlling a specific pest according to claim 7 or 8, wherein the amount of the specific pest control component released is 0.01mg/m 3 ～250mg/m 3 The specific noxious substance control constant-volume aerosol product is sprayed.
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| PCT/JP2021/009146 WO2021182433A1 (en) | 2020-03-13 | 2021-03-09 | Fixed-amount spray aerosol product for controlling specific hazardous things, and method for controlling specific hazardous things using same |
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| CN115568465A (en) * | 2018-12-14 | 2023-01-06 | 大日本除虫菊株式会社 | Method for controlling pests and mites, and aerosol for controlling pests and mites |
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- 2021-03-09 CN CN202180010408.5A patent/CN115023138A/en active Pending
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| WO2021182433A1 (en) | 2021-09-16 |
| JP7049511B2 (en) | 2022-04-06 |
| JP2022009644A (en) | 2022-01-14 |
| JP7016991B1 (en) | 2022-02-07 |
| JPWO2021182433A1 (en) | 2021-09-16 |
| TWI796648B (en) | 2023-03-21 |
| TW202142113A (en) | 2021-11-16 |
| JP2021155441A (en) | 2021-10-07 |
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