CN114999294A - Functional food simulated digestion and decomposition device - Google Patents
Functional food simulated digestion and decomposition device Download PDFInfo
- Publication number
- CN114999294A CN114999294A CN202210723027.8A CN202210723027A CN114999294A CN 114999294 A CN114999294 A CN 114999294A CN 202210723027 A CN202210723027 A CN 202210723027A CN 114999294 A CN114999294 A CN 114999294A
- Authority
- CN
- China
- Prior art keywords
- section
- intestinal
- infiltration
- thick bamboo
- support frame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000029087 digestion Effects 0.000 title claims abstract description 41
- 235000013376 functional food Nutrition 0.000 title claims abstract description 31
- 238000000354 decomposition reaction Methods 0.000 title claims abstract description 28
- 238000003756 stirring Methods 0.000 claims abstract description 48
- 210000002784 stomach Anatomy 0.000 claims abstract description 48
- 230000000968 intestinal effect Effects 0.000 claims abstract description 45
- 238000004088 simulation Methods 0.000 claims abstract description 43
- 210000000214 mouth Anatomy 0.000 claims abstract description 41
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 39
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims abstract description 38
- 235000017491 Bambusa tulda Nutrition 0.000 claims abstract description 38
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims abstract description 38
- 241001330002 Bambuseae Species 0.000 claims abstract description 35
- 239000011425 bamboo Substances 0.000 claims abstract description 35
- 230000008595 infiltration Effects 0.000 claims abstract description 35
- 238000001764 infiltration Methods 0.000 claims abstract description 35
- 238000009413 insulation Methods 0.000 claims abstract description 29
- 210000003296 saliva Anatomy 0.000 claims abstract description 24
- 239000012530 fluid Substances 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims description 41
- 210000004051 gastric juice Anatomy 0.000 claims description 29
- 210000000813 small intestine Anatomy 0.000 claims description 29
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 22
- 210000002429 large intestine Anatomy 0.000 claims description 22
- 230000002496 gastric effect Effects 0.000 claims description 19
- 238000003780 insertion Methods 0.000 claims description 9
- 230000037431 insertion Effects 0.000 claims description 9
- 230000001105 regulatory effect Effects 0.000 claims description 7
- 210000000936 intestine Anatomy 0.000 claims description 4
- 241000209128 Bambusa Species 0.000 claims description 3
- 230000035515 penetration Effects 0.000 claims description 3
- 210000001124 body fluid Anatomy 0.000 abstract description 14
- 239000010839 body fluid Substances 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 6
- 210000000056 organ Anatomy 0.000 abstract description 6
- 238000012360 testing method Methods 0.000 abstract description 5
- 238000006243 chemical reaction Methods 0.000 description 16
- 235000013305 food Nutrition 0.000 description 10
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 9
- 238000002156 mixing Methods 0.000 description 6
- 210000001819 pancreatic juice Anatomy 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 210000000941 bile Anatomy 0.000 description 5
- 238000013461 design Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 3
- 239000001110 calcium chloride Substances 0.000 description 3
- 229910001628 calcium chloride Inorganic materials 0.000 description 3
- 235000011148 calcium chloride Nutrition 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 239000012466 permeate Substances 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 230000008855 peristalsis Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102100031416 Gastric triacylglycerol lipase Human genes 0.000 description 1
- 108010019160 Pancreatin Proteins 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000005094 computer simulation Methods 0.000 description 1
- 230000009193 crawling Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 108010091264 gastric triacylglycerol lipase Proteins 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 229940055695 pancreatin Drugs 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000007180 physiological regulation Effects 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000002277 temperature effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Computational Mathematics (AREA)
- Mathematical Analysis (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Algebra (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Mathematical Optimization (AREA)
- Mathematical Physics (AREA)
- Pure & Applied Mathematics (AREA)
- Business, Economics & Management (AREA)
- Educational Administration (AREA)
- Educational Technology (AREA)
- Theoretical Computer Science (AREA)
- Instructional Devices (AREA)
Abstract
The invention relates to the technical field of simulated digestion and decomposition devices, and provides a functional food simulated digestion and decomposition device which has better simulation effect on each part of a human oral cavity, a stomach and an intestinal system, smaller real difference between the whole size structure and organs in a human body, more uniform body fluid infiltration, wider infiltration range, smaller whole scheme and actual in-out and better reliability of test data, comprises a constant temperature box, a plurality of first peristaltic pumps and a plurality of second peristaltic pumps, and also comprises an oral cavity simulation system, a stomach simulation system and an intestinal simulation system, wherein the constant temperature box comprises a support frame and three heat insulation plates, the three heat insulation plates can be detachably arranged in the support frame, the oral cavity simulation system comprises a stirring cylinder and an oral cavity fluid cylinder, the stirring cylinder is fixedly connected to the top end of the support frame, a stirring device is arranged in the stirring cylinder, and a feeding port is formed in the stirring cylinder, the outside of churn is provided with the saliva infiltration section of thick bamboo, is provided with a plurality of saliva infiltration holes on the lateral wall of churn.
Description
Technical Field
The invention relates to the technical field of simulated digestion and decomposition devices, in particular to a simulated digestion and decomposition device for functional food.
Background
The first function of the functional food is nutrition, the second function is sensory enjoyment when in use, namely, the color, the fragrance and the taste of the food are utilized to increase appetite, the third function is the function of regulating the physiological activity of a human body, the components which really have the physiological regulation function in the functional food are called physiological active components or functional factors, the functional components comprise hundreds of varieties, eight major categories, namely functional sweeteners, active oligosaccharides, active polysaccharides, active oil, biological antioxidants, active polypeptides, active proteins, lactic acid bacteria and other active components, with the continuous and deep research, new functional factors are discovered in succession, and in order to better develop the research on the functional food, a functional food simulated digestion and decomposition device is provided to realize the visual research on the digestion and decomposition state of the functional food.
Through retrieval, a Chinese patent with publication number CN113744610A, published on 12.3.2021, discloses a simple in vitro dynamic simulation digestion device and a use method, which is roughly described as comprising a simulation oral cavity part, a simulation stomach part and a simulation small intestine part which are connected in sequence, wherein a first bracket, a second bracket and a third bracket are arranged in a constant temperature box, the simulation oral cavity part is an oral reaction bottle, the oral reaction bottle is hung below the first bracket, the simulation stomach part consists of a gastric juice storage bottle and a gastric reaction bottle, the gastric reaction bottle is hung below the second bracket, the gastric juice storage bottle is connected below the first bracket, the gastric reaction bottle is connected with the gastric juice storage bottle and the gastric reaction bottle, the simulation small intestine part consists of a bile storage bottle, a pancreatic juice storage bottle and a small intestine reaction bottle, wherein the bile storage bottle and the pancreatic juice storage bottle are vertically hung below the second bracket, the small intestine reaction bottle is vertically hung below the third bracket, when the device is used, before simulated digestion, a thermostat is opened, the temperature is adjusted to 37 ℃, after the temperature is stabilized, simulated saliva, a CaCl2(H2O)2 solution and distilled water are mixed and then are added into an oral cavity reaction bottle from a sample inlet, simulated gastric juice, a CaCl2(H2O)2 solution, an HCl solution and distilled water are mixed and then are respectively added into the gastric juice storage bottle and the gastric juice reaction bottle from a first simulated gastric juice inlet and a second simulated gastric juice inlet, simulated bile is added into the bile storage bottle from a simulated bile inlet, the simulated intestinal juice, the CaCl2(H2O)2 solution and the distilled water are mixed and then are respectively added into the pancreatic juice storage bottle and the small intestine reaction bottle from the simulated pancreatic juice inlet and the bile-pancreatic juice mixed solution inlet, all parts are connected, a control switch is in a closed state, and a reaction stage is as follows: adding saliva amylase solution and a sample to be digested into an oral reaction bottle from a sample inlet, adding pepsin and gastric lipase solution into a gastric storage bottle from a first simulated gastric juice inlet, adding the sample to be digested, immediately turning on the first control switch, the second control switch and the first peristaltic pump and regulating the flow rate, after turning on the first control switch, the oral cavity digestion sample enters the stomach reaction bottle from the oral cavity digestion sample outlet through the oral cavity digestion sample inlet, adding pancreatin into the pancreatic juice storage bottle from the simulated pancreatic juice inlet after 5min, turning on the third control switch, the fourth control switch, the fifth control switch and the second peristaltic pump and regulating the flow rate, turning on the third control switch, and the stomach digestion sample enters the intestinal reaction bottle from the stomach digestion sample outlet through the stomach digestion sample inlet, the sixth control switch is opened after 2 hours, and the sample is taken from the intestinal digestion sample outlet for subsequent test analysis.
Although the prior art scheme can initially realize dynamic simulated digestion of food, the integral structure of the prior art scheme is realized by a plurality of bottles, so the actual difference with organs in a human body is larger, particularly, the total length of small intestines in the human body is about 4-6 meters, the 4-6 meters of small intestines can play a role in secreting body fluid, the action range of a single small intestine reaction bottle is smaller, and simultaneously, the oral cavity, the stomach and the intestinal tract system uniformly secrete corresponding body fluid and are not similar to single pipeline input, so the whole and actual access of the technical scheme is larger, and the reliability of data acquired by a test is poorer.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a functional food simulated digestion and decomposition device which has better simulation effect on all parts of the oral cavity, the stomach and the intestinal system of a human body, smaller real difference between the whole size structure and the organs in the human body, more uniform body fluid infiltration, wider infiltration range, smaller whole scheme and actual in-out and better reliability of test data.
(II) technical scheme
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides a function food simulation digestion decomposition device, includes thermostated container, a plurality of first peristaltic pumps and a plurality of second peristaltic pumps, still includes oral cavity emulation system, stomach emulation system and intestinal simulation system, the thermostated container includes support frame and three heated board, three the heated board all can be dismantled and install in the support frame, oral cavity emulation system includes churn and oral cavity liquid section of thick bamboo, churn fixed connection is in the top of support frame is provided with the comminution device in the churn, has seted up on the churn and has added the food mouth, and the outside of churn is provided with saliva infiltration section of thick bamboo, is provided with a plurality of saliva infiltration holes on the lateral wall of churn, and saliva infiltration section of thick bamboo and oral cavity liquid section of thick bamboo intercommunication, and oral cavity liquid section of thick bamboo pass through bracing piece fixed connection at the top of support frame, and oral cavity liquid section of thick bamboo has seted up the filling opening, and stomach emulation system includes emulation stomach and stomach liquid section of thick bamboo, emulation stomach and churn intercommunication, the outside of emulation stomach is provided with a gastric juice infiltration section of thick bamboo, and is a plurality of first peristaltic pump is all installed on a gastric juice infiltration section of thick bamboo, a gastric juice infiltration section of thick bamboo and a gastric juice section of thick bamboo intercommunication, gastric juice section of thick bamboo fixed connection have seted up on the gastric juice section of thick bamboo and have added the liquid mouth, intestinal simulation system includes small intestine section and large intestine section, small intestine section and large intestine section intercommunication each other, and small intestine section and emulation stomach intercommunication, the outside of small intestine section and the outside of large intestine section all are provided with the infiltration intestinal, two the infiltration intestinal communicates each other, and an infiltration intestinal intercommunication in two infiltration intestines has an intestinal juice section of thick bamboos, the equal fixed connection of infiltration intestinal juice section of thick bamboos is provided with on the intestinal juice section of thick bamboo and puts the liquid mouth, and is a plurality of the second peristaltic pump equidistance is installed on the infiltration intestinal, installs the supplementary peristaltic system of a plurality of intestinal in the support frame.
On the basis of the scheme, the intestinal tract auxiliary creeping system comprises an electric push rod, an upper track plate and a lower track plate, wherein the upper track plate and the lower track plate are fixedly connected in the support frame, and a sliding connection is arranged between the upper track plate and the lower track plate to form an auxiliary creeping frame for intestinal tract auxiliary creeping, the electric push rod is arranged in the support frame, and a telescopic rod of the electric push rod is connected with the auxiliary creeping frame.
On the basis of the scheme, preferably, insertion grooves are formed in the left end, the rear end and the front end of the supporting frame, the three insulation boards are respectively inserted into the three insertion grooves, and the supporting frame is in threaded connection with tightening bolts used for positioning the insulation boards.
Further on the basis of the scheme, the stirring device comprises a driving motor and a stirring shaft, a plurality of stirring knives are installed on the stirring shaft, the stirring shaft is rotatably connected in the stirring cylinder, the top end of the stirring shaft penetrates through the stirring cylinder and extends out of the stirring cylinder, the driving motor is installed on the top end of the stirring cylinder, and the output shaft of the driving motor is fixedly connected with the stirring shaft.
On the basis of the scheme, the supporting frame is further provided with a plurality of side grooves which are respectively communicated with the insertion grooves.
On the basis of the scheme, the heat insulation plate is of a hollow structure, and a heat insulation layer is arranged at one end, close to the simulated stomach, of the heat insulation plate.
As the scheme further, the liquid adding port and the liquid placing port are internally provided with the inclined bent pipes, the inclined bent pipes are connected with the top caps through threads, and the top caps are provided with vent holes.
As a further improvement of the above scheme, regulating valves are arranged between the saliva permeation cylinder and the oral liquid cylinder, between the gastric liquid permeation cylinder and the gastric liquid cylinder, and between one of the permeation intestinal tracts and the intestinal liquid cylinder communicated therewith.
As a further aspect of the above, a control valve is installed at the front end of the large intestine section.
As a further scheme of the scheme, a plurality of hand-held rings are installed at the top end of the supporting frame.
(III) advantageous effects
Compared with the prior art, the invention provides a functional food simulated digestion and decomposition device, which has the following beneficial effects:
1. according to the invention, through the design of the oral cavity simulation system, the stomach simulation system and the intestinal canal simulation system, the simulation effect of each part of the oral cavity, the stomach and the intestinal system of the human body corresponding to the functional food simulated digestion decomposition device is better, and the actual difference between the whole size structure and the organs in the human body is smaller.
2. According to the invention, the saliva, the gastric juice and the intestinal juice can be permeated in a large range respectively through the design of the saliva permeating cylinder, the gastric juice permeating cylinder and the intestinal permeation, the body fluid can be permeated uniformly, the permeation range is wide, and the high fit with a real human body can be realized.
3. In the invention, the driving of the simulated peristalsis of the mixing drum, the simulated stomach, the small intestine section and the large intestine section is realized through the matching of the first peristaltic pump, the second peristaltic pump and the intestinal tract auxiliary peristalsis system, the whole scheme is smaller than the actual in-out and the actual in-out, and the reliability of test data is better.
Drawings
FIG. 1 is a partially cut-away perspective view of the present invention;
FIG. 2 is a schematic view of a partially sectioned perspective structure of the combination of a small intestine section, a large intestine section, and an infiltrating intestinal tract of the present invention;
FIG. 3 is a schematic perspective view of the insulation board of the present invention;
FIG. 4 is a schematic perspective view of the present invention;
FIG. 5 is a schematic perspective view of the rear side view of the present invention.
In the figure: 1. a support frame; 2. a thermal insulation board; 3. a mixing drum; 4. an oral fluid cartridge; 5. adding a feed port; 6. a saliva penetration cartridge; 7. a support bar; 8. simulating a stomach; 9. a gastric fluid cylinder; 10. a gastric juice infiltration cylinder; 11. a small intestine section; 12. a large intestine section; 13. penetrating the intestinal tract; 14. an intestinal fluid cartridge; 15. an upper track plate; 16. a lower track plate; 17. an auxiliary crawling frame; 18. jacking the bolt; 19. a stirring shaft; 20. a mincing knife; 21. a side groove; 22. a thermal insulation layer; 23. bending the pipe obliquely; 24. a top cap; 25. a hand ring.
Detailed Description
Examples
Referring to fig. 1-5, a functional food simulated digestion decomposition device comprises a thermostat, a plurality of first peristaltic pumps, a plurality of second peristaltic pumps, an oral cavity simulation system, a stomach simulation system and an intestinal tract simulation system, wherein the design of the oral cavity simulation system, the stomach simulation system and the intestinal tract simulation system ensures that the simulation effect of each part of the oral cavity, the stomach and the intestinal system of a human body corresponding to the functional food simulated digestion decomposition device is better, the difference between the whole size structure and the reality of organs in the human body is smaller, the thermostat comprises a support frame 1 and three insulation boards 2, the insulation boards 2 are of a hollow structure, one end of each insulation board 2 close to a simulated stomach 8 is provided with an insulation layer 22, the weight reduction of each insulation board 2 is realized, the three insulation boards 2 can reduce heat conduction, the three insulation boards 2 can be detachably arranged in the support frame 1, and the left end, the rear end and the front end of the support frame 1 are provided with insertion grooves, the three insulation boards 2 are respectively inserted into the three insertion grooves, the support frame 1 is in threaded connection with puller bolts 18 used for positioning the insulation boards 2, the scope of the stomach simulation system and the intestinal simulation system is guaranteed to be matched with the body temperature of a human body, so that the environment is basically similar, the support frame 1 is provided with a plurality of side grooves 21 respectively communicated with the insertion grooves, the insulation boards 2 can be conveniently inserted into and taken out of the support frame, the insulation boards 2 can be conveniently assembled, meanwhile, the support frame 1 is convenient to maintain, the top end of the support frame 1 is provided with a plurality of hand-held rings 25, when the functional food digestion simulation decomposition device needs to move, the lifting and moving of the functional food digestion simulation decomposition device can be realized through the hand-held rings 25, the oral cavity simulation system comprises a mixing drum 3 and an oral cavity liquid drum 4, the mixing drum 3 is fixedly connected to the top end of the support frame 1, and a crushing device is arranged in the mixing drum 3, the stirring device comprises a driving motor and a stirring shaft 19, a plurality of stirring knives 20 are installed on the stirring shaft 19, the stirring shaft 19 is rotatably connected in the stirring cylinder 3, the top end of the stirring shaft 19 penetrates through the stirring cylinder 3 and extends out of the stirring cylinder 3, the driving motor is installed on the top end of the stirring cylinder 3, an output shaft of the driving motor is fixedly connected with the stirring shaft 19, the simulation of the chewing function of the human oral cavity on things is realized, an addition port 5 is formed in the stirring cylinder 3, a saliva permeation cylinder 6 is arranged outside the stirring cylinder 3, a plurality of saliva permeation holes are formed in the outer side wall of the stirring cylinder 3, the saliva permeation cylinder 6 is communicated with an oral liquid cylinder 4, the oral liquid cylinder 4 is fixedly connected to the top end of the support frame 1 through a support rod 7, a liquid addition port is formed in the oral liquid cylinder 4, and saliva is convenient to add.
It should be further explained that the stomach simulation system includes a simulated stomach 8 and a gastric fluid cylinder 9, the simulated stomach 8 is communicated with the mixing cylinder 3, a gastric fluid permeation cylinder 10 is arranged outside the simulated stomach 8, a plurality of first peristaltic pumps are all installed on the gastric fluid permeation cylinder 10, the gastric fluid permeation cylinder 10 is communicated with the gastric fluid cylinder 9, the gastric fluid cylinder 9 is fixedly connected in the support frame 1, a fluid feeding port is arranged on the gastric fluid cylinder 9, the intestinal simulation system includes a small intestine section 11 and a large intestine section 12, the small intestine section 11 is communicated with the simulated stomach 8, the permeable intestinal tracts 13 are arranged outside the small intestine section 11 and outside the large intestine section 12, the two permeable intestinal tracts 13 are communicated with each other, one of the two permeable intestinal tracts 13 is communicated with the intestinal fluid cylinder 14, the permeable intestinal tracts 13 and the intestinal fluid cylinder 14 are both fixedly connected in the support frame 1, and the design of the saliva permeation cylinder 6, the gastric fluid permeation cylinder 10 and the permeable intestinal tracts 13 is adopted, the large-scale permeation of saliva, gastric juice and intestinal juice is respectively realized, the permeation of body fluid is relatively uniform, the permeation range is wide, the high-degree fit with a real human body is realized, a liquid containing port is arranged on the intestinal juice cylinder 14, inclined bent pipes 23 are respectively arranged in the liquid adding port, the liquid adding port and the liquid containing port, the body fluid is conveniently added, top caps 24 are in threaded connection on the inclined bent pipes 23, vent holes are formed in the top caps 24, the external gas can conveniently enter, the phenomenon that the body fluid cannot permeate due to space negative pressure can be avoided, the influence on the simulated secretion effect is avoided, a plurality of second peristaltic pumps are equidistantly arranged on the intestinal tract 13, a plurality of intestinal tract auxiliary peristaltic systems are arranged in the supporting frame 1 and comprise electric push rods, upper track plates 15 and lower track plates 16, the upper track plates 15 and the lower track plates 16 are fixedly connected in the supporting frame 1, and auxiliary peristaltic frames 17 for the intestinal tract auxiliary are slidably connected between the upper track plates 15 and the lower track plates 16, electric putter installs in support frame 1, and electric putter's telescopic link is connected with supplementary peristaltic rack 17, through first peristaltic pump, the cooperation of the supplementary peristaltic system of second peristaltic pump and intestinal, realize churn 3, emulation stomach 8, the drive of the emulation wriggling of small intestine section 11 and large intestine section 12, whole scheme is less with actual discrepancy, experimental data reliability is better, between saliva infiltration section of thick bamboo 6 and oral cavity liquid section of thick bamboo 4, between gastric juice infiltration section of thick bamboo 10 and the gastric juice section of thick bamboo 9 and the infiltration intestinal 13 in the intestines of infiltration 13 all be provided with the governing valve rather than between the intestinal liquid section of thick bamboo 14 of intercommunication, the secreted volume of body fluid can be controlled, the control valve is installed to the front end of large intestine section 12, realize the emulation of anus structure, the discharge of the functional food after the control large intestine section 12 internal digestion.
In summary, the working principle and working process of the functional food simulated digestion and decomposition device are that, when in use, the functional food simulated digestion and decomposition device is firstly placed at a place where it is needed, and the electric devices of the driving motor, the electric push rod, the first peristaltic pump and the second peristaltic pump are completed, the electric devices of the driving motor, the electric push rod, the first peristaltic pump and the second peristaltic pump are all mature products selected on the market according to the use requirement and the installation space, the structure and principle of the device are not improved in this place, and meanwhile, the device is respectively matched with a use instruction and a manufacturer technical support, so that the device is not repeated, and then corresponding body fluids are added into the oral liquid cylinder 4, the gastric liquid cylinder 9 and the intestinal liquid cylinder 14, and can be prepared according to the components of the body fluids in the simple in-vitro dynamic simulated digestion device with the publication number of CN113744610A and the comparative patent of the use method, after body fluid is added, a plurality of regulating valves are opened, the flow of the body fluid is controlled by the regulating valves, a plurality of body fluids respectively enter a saliva permeation cylinder 6, a gastric juice permeation cylinder 10 and a permeation intestinal tract 13 and respectively permeate a stirring cylinder 3, a simulated stomach 8, a small intestine section 11 and a large intestine section 12, after the regulation is finished, a driving motor, a first peristaltic pump and a second peristaltic pump are started, functional food is put into the stirring cylinder 3 through a feeding port 5, the functional food sequentially enters the stirring cylinder 3, the simulated stomach 8, the small intestine section 11 and the large intestine section 12 under the action of gravity, a crushing knife 20 works after the functional food enters the stirring cylinder 3 to stir the food, the permeated saliva is wetted when the food is stirred, the food treated by the stirring cylinder 3 enters the simulated stomach 8, the first peristaltic pump works to realize the auxiliary peristaltic action of the simulated stomach 8, and the gastric juice simultaneously permeates the food, food after handling through emulation stomach 8 can be through the processing of small intestine section 11 and large intestine section 12, intestinal juice infiltrates small intestine section 11 and large intestine section 12 in this process, the work of second peristaltic pump realizes the supplementary wriggling to small intestine section 11 and large intestine section 12 with supplementary wriggling frame 17 by the reciprocal push-and-pull of electric putter simultaneously, thereby guarantee the emulation of food digestion, wherein shape and size of emulation stomach 8, the size of small intestine section 11 and the size of large intestine section 12 all carry out emulation design according to the size of each corresponding organ of normal person, to the constant temperature effect of thermostated container, can put into the insulation can in the constant temperature environment, also can carry out the control of temperature through installing the thermostat additional, only need satisfy human temperature's emulation can, this part belongs to conventional equipment, it is not repeated here.
Claims (10)
1. A functional food digestion and decomposition simulation device comprises
The device comprises a constant temperature box, a plurality of first peristaltic pumps and a plurality of second peristaltic pumps, and is characterized by further comprising an oral cavity simulation system, a stomach simulation system and an intestinal tract simulation system, wherein the oral cavity simulation system, the stomach simulation system and the intestinal tract simulation system are arranged in the constant temperature box
The constant temperature box comprises a support frame and three heat insulation plates, wherein the three heat insulation plates are detachably arranged in the support frame, and the constant temperature box comprises
Oral cavity emulation system includes churn and oral cavity liquid section of thick bamboo, churn fixed connection is in the top of support frame is provided with the comminution device in the churn, has seted up on the churn and has added the edible mouth, and the outside of churn is provided with saliva infiltration section of thick bamboo, is provided with a plurality of saliva infiltration holes on the lateral wall of churn, and saliva infiltration section of thick bamboo and oral cavity liquid section of thick bamboo intercommunication, and oral cavity liquid section of thick bamboo passes through bracing piece fixed connection on the top of support frame, and the liquid feeding mouth has been seted up to oral cavity liquid section of thick bamboo, and wherein
Stomach simulation system includes emulation stomach and a stomach liquid section of thick bamboo, emulation stomach and churn intercommunication, the outside of emulation stomach is provided with the gastric juice infiltration section of thick bamboo, and is a plurality of first peristaltic pump is all installed on the gastric juice infiltration section of thick bamboo, and the gastric juice infiltration section of thick bamboo communicates with the gastric juice section of thick bamboo, and gastric juice section of thick bamboo fixed connection has seted up on the gastric juice section of thick bamboo and has added the liquid mouth in the support frame, and wherein
Intestinal simulation system includes small intestine section and large intestine section, small intestine section and large intestine section communicate each other, and small intestine section and emulation stomach intercommunication, and the outside of small intestine section and the outside of large intestine section all are provided with the infiltration intestinal, two the intercommunication each other of infiltration intestinal, and an infiltration intestinal intercommunication in two infiltration intestines has an intestinal liquid section of thick bamboo, the equal fixed connection of infiltration intestinal and intestinal liquid section of thick bamboos is provided with on the intestinal liquid section of thick bamboo and puts the liquid mouth, and is a plurality of the second peristaltic pump equidistance is installed on the infiltration intestinal, installs the supplementary peristaltic system of a plurality of intestinal in the support frame.
2. The simulated digestion and decomposition device for functional food according to claim 1, wherein the intestinal tract auxiliary peristaltic system comprises an electric push rod, an upper track plate and a lower track plate, the upper track plate and the lower track plate are both fixedly connected in the support frame, an auxiliary peristaltic rack for intestinal tract auxiliary peristaltic is slidably connected between the upper track plate and the lower track plate, the electric push rod is installed in the support frame, and a telescopic rod of the electric push rod is connected with the auxiliary peristaltic rack.
3. The simulated digestion and decomposition device for functional food according to claim 2, wherein the left end, the rear end and the front end of the support frame are provided with insertion grooves, the three insulation boards are respectively inserted into the three insertion grooves, and the support frame is in threaded connection with tightening bolts for positioning the insulation boards.
4. The device for simulating digestion and decomposition of functional food according to claim 3, wherein the stirring device comprises a driving motor and a stirring shaft, a plurality of stirring knives are installed on the stirring shaft, the stirring shaft is rotatably connected in the stirring cylinder, the top end of the stirring shaft penetrates through the stirring cylinder and extends out of the stirring cylinder, the driving motor is installed at the top end of the stirring cylinder, and the output shaft of the driving motor is fixedly connected with the stirring shaft.
5. The simulated digestion and decomposition device for functional food according to claim 4, wherein the supporting frame is provided with a plurality of side grooves respectively communicated with the plurality of insertion grooves.
6. The simulated digestion and decomposition device for functional food according to claim 5, wherein the heat insulation board is of a hollow structure, and a heat insulation layer is arranged at one end of the heat insulation board close to the simulated stomach.
7. The simulated digestion and decomposition device for functional food according to claim 6, wherein the liquid feeding port, the liquid feeding port and the liquid placing port are all provided with an inclined elbow, the inclined elbow is connected with a top cap through a thread, and the top cap is provided with a vent hole.
8. The simulated digestion and decomposition device for functional food according to claim 7, wherein regulating valves are disposed between the saliva penetration cylinder and the oral fluid cylinder, between the gastric fluid penetration cylinder and the gastric fluid cylinder, and between one of the penetrated intestines and the intestinal fluid cylinder communicated therewith.
9. The simulated digestion and decomposition device for functional food according to claim 8, wherein the front end of the large intestine section is equipped with a control valve.
10. The simulated digestion and decomposition device according to claim 9, wherein a plurality of hand-held rings are installed on the top end of the supporting frame.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210723027.8A CN114999294A (en) | 2022-06-24 | 2022-06-24 | Functional food simulated digestion and decomposition device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210723027.8A CN114999294A (en) | 2022-06-24 | 2022-06-24 | Functional food simulated digestion and decomposition device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114999294A true CN114999294A (en) | 2022-09-02 |
Family
ID=83037796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210723027.8A Pending CN114999294A (en) | 2022-06-24 | 2022-06-24 | Functional food simulated digestion and decomposition device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114999294A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105702146A (en) * | 2015-12-31 | 2016-06-22 | 南通东概念新材料有限公司 | Bionic dynamic mouse stomach-duodenum digestive system simulation device and simulation experiment method |
| US20160351079A1 (en) * | 2013-12-12 | 2016-12-01 | Sandoz Ag | Apparatus For Simulating The Function Of Human Stomach And/Or Human Intestine |
| WO2017065595A2 (en) * | 2015-10-14 | 2017-04-20 | Atqia, S. De R.L. De C.V. | Automated system for simulating the human digestive tract |
| CN208889159U (en) * | 2018-05-21 | 2019-05-21 | 赵金平 | A kind of Gastroenterology dept.'s demonstrating model |
| CN209625582U (en) * | 2018-09-11 | 2019-11-12 | 陕西科技大学 | A kind of semi-permeable membrane judicial entity alimentary canal simulator |
| CN211264777U (en) * | 2020-03-16 | 2020-08-14 | 宋孝辉 | Digestive system demonstration model |
| CN213659810U (en) * | 2020-09-18 | 2021-07-09 | 徐州工程学院 | Food simulation intestines and stomach digestion intelligent control device |
-
2022
- 2022-06-24 CN CN202210723027.8A patent/CN114999294A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160351079A1 (en) * | 2013-12-12 | 2016-12-01 | Sandoz Ag | Apparatus For Simulating The Function Of Human Stomach And/Or Human Intestine |
| WO2017065595A2 (en) * | 2015-10-14 | 2017-04-20 | Atqia, S. De R.L. De C.V. | Automated system for simulating the human digestive tract |
| CN105702146A (en) * | 2015-12-31 | 2016-06-22 | 南通东概念新材料有限公司 | Bionic dynamic mouse stomach-duodenum digestive system simulation device and simulation experiment method |
| CN208889159U (en) * | 2018-05-21 | 2019-05-21 | 赵金平 | A kind of Gastroenterology dept.'s demonstrating model |
| CN209625582U (en) * | 2018-09-11 | 2019-11-12 | 陕西科技大学 | A kind of semi-permeable membrane judicial entity alimentary canal simulator |
| CN211264777U (en) * | 2020-03-16 | 2020-08-14 | 宋孝辉 | Digestive system demonstration model |
| CN213659810U (en) * | 2020-09-18 | 2021-07-09 | 徐州工程学院 | Food simulation intestines and stomach digestion intelligent control device |
Non-Patent Citations (1)
| Title |
|---|
| 伍鹏;王晶晶;董志忠;陈晓东;: "体外仿生消化系统的研究进展――从静态到动态", 生物产业技术, no. 06, 15 November 2019 (2019-11-15) * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1907108B1 (en) | Apparatus, system and method | |
| CN114999294A (en) | Functional food simulated digestion and decomposition device | |
| CN105695323A (en) | High-efficiency oligosaccharide biological enzyme method production process and device | |
| CN112094732A (en) | Culture apparatus is collected to fungus crowd of intestinal disease inspection usefulness | |
| CN109984336A (en) | A kind of ferment drink and preparation method thereof | |
| CN116836787A (en) | Biological reaction system | |
| CN211005335U (en) | A fermenting installation for microorganism | |
| CN210656871U (en) | Novel edible mushroom fermentation culture device | |
| CN207619409U (en) | A kind of external digestion system simulator | |
| CN210030703U (en) | Fermentation device of bdellovibrio bacteriovorus | |
| CN208065826U (en) | A kind of soybean lecithin extractor | |
| CN208604121U (en) | A kind of spawn fermentation tank | |
| CN219922777U (en) | Water bath heating stirring device for biomass composite carbon source preparation | |
| CN212467193U (en) | A draw jar for lotus plumule low temperature refines | |
| CN221432820U (en) | Emulsifying tank for pharmaceutical industry | |
| CN212894523U (en) | Extraction element is used in production of second allicin | |
| CN215947263U (en) | Sour bamboo shoot fermentation tank device with stirring function | |
| CN215901436U (en) | Ventilating and stirring device for removing fishy smell of spirulina | |
| CN219930111U (en) | Compound EM fungus synthesizer | |
| CN219003086U (en) | Polydextrose polymerization reaction device | |
| CN213819132U (en) | Biocontrol bacteria liquid preparation watering device of strawberry cultivation usefulness | |
| CN108793530A (en) | A kind of environment-friendly type wastewater treatment equipment for biotechnology research | |
| CN216864167U (en) | A high-efficient fermentation cylinder for production of sweet potato probiotic beverage | |
| CN219449714U (en) | Aerobic biological fermentation tank | |
| CN215517377U (en) | Food processing fermenting installation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |