CN114994739A - SiPM time signal reader - Google Patents

SiPM time signal reader Download PDF

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CN114994739A
CN114994739A CN202210653983.3A CN202210653983A CN114994739A CN 114994739 A CN114994739 A CN 114994739A CN 202210653983 A CN202210653983 A CN 202210653983A CN 114994739 A CN114994739 A CN 114994739A
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黄秋
赵指向
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Shanghai Jiao Tong University
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Abstract

本发明的目的在于提供一种SiPM时间信号读取器,包括:信号引出模块,信号缓冲模块和信号求和模块;所述信号引出模块包括若干SiPM组成的阵列,每个所述SiPM包括两个输出端,其中第一输出端串联一检测电阻;所述第一输出端直接引出的信号作为该路SiPM输出的时间信号;所述第一输出端串联所述检测电阻后引出的信号作为第一输出信号,所述SiPM的第二输出端引出的信号作为第二输出信号;所述信号缓冲模块包括若干射频放大器;所述每路SiPM输出的时间信号被引入一个所述射频放大器;所述信号求和模块包括加法放大电路,每个所述射频放大器的输出信号被接入所述加法放大电路进行合并,所述合并后的信号作为所述SiPM阵列的时间信号。

Figure 202210653983

The purpose of the present invention is to provide a SiPM time signal reader, including: a signal extraction module, a signal buffer module and a signal summing module; the signal extraction module includes an array composed of several SiPMs, each of which includes two SiPMs. Output terminal, wherein the first output terminal is connected in series with a detection resistor; the signal directly drawn from the first output terminal is used as the time signal output by the SiPM; the signal drawn from the first output terminal in series with the detection resistor is used as the first output terminal. output signal, the signal drawn from the second output end of the SiPM is used as the second output signal; the signal buffer module includes several radio frequency amplifiers; the time signal output by each channel of SiPM is introduced into one of the radio frequency amplifiers; the signal The summation module includes an addition and amplification circuit, and the output signal of each of the radio frequency amplifiers is connected to the addition and amplification circuit for combination, and the combined signal is used as the time signal of the SiPM array.

Figure 202210653983

Description

一种SiPM时间信号读取器A SiPM time signal reader

技术领域technical field

本发明专利涉及于医学影像设备技术领域,具体涉及一种基于射频放大器的SiPM时间信号合并读取电路。The patent of the present invention relates to the technical field of medical imaging equipment, in particular to a combined reading circuit of SiPM time signals based on a radio frequency amplifier.

背景技术Background technique

正电子发射型计算机断层显像系统(PET)已经是肿瘤等疾病的首选诊断成像技术,其原理是通过对γ光子事件的能量、时间等信息进行测量实现图像重建。Positron emission tomography (PET) has been the preferred diagnostic imaging technology for tumors and other diseases. Its principle is to achieve image reconstruction by measuring the energy, time and other information of gamma photon events.

目前基于硅半导体的硅光电倍增管(Silicon Photomultiplier,简称SiPM)的PET系统已经逐渐成为主流。SiPM是由数百或数千个工作在盖格模式下由自猝灭的单光子雪崩光电二极管(SPAD)组成,其逻辑结构简图如图1。At present, the PET system based on silicon photomultiplier (Silicon Photomultiplier, SiPM for short) has gradually become the mainstream. SiPM is composed of hundreds or thousands of self-quenched single-photon avalanche photodiodes (SPADs) operating in Geiger mode, and its logical structure is shown in Figure 1.

现有SiPM技术的瓶颈之一就是其时间信号读取电路。由于PET系统中SiPM数量可高达上万片,若对上万片SiPM的输出信号进行一对一读出,其电子学部分使用的硬件资源将相当庞大,可行性较低。当前很多系统的解决方法是把多个SiPM的信号短接起来合并为更少的通道再用后续的电子学系统进行测量,这类方法虽然能够减少所需的测量通道数目,但是将SiPM的直接信号进行合并会导致SiPM的时间信号产生衰减并将更多的噪声混入信号,进而导致时间性能下降。因此实现一种能够减小SiPM时间信号合并后衰减并且不引入过多的噪声的时间信号合并读取电路对于发挥SiPM的优势,实现更高的时间分辨率有重大意义One of the bottlenecks of existing SiPM technology is its timing signal readout circuitry. Since the number of SiPMs in a PET system can be as high as tens of thousands, if the output signals of tens of thousands of SiPMs are read out one-to-one, the hardware resources used in the electronics part will be quite large, and the feasibility is low. The current solution for many systems is to short-circuit the signals of multiple SiPMs and combine them into fewer channels, and then use the subsequent electronic systems for measurement. Although this method can reduce the number of measurement channels required, the direct Combining the signals causes the SiPM's time signal to attenuate and mix more noise into the signal, resulting in degraded time performance. Therefore, it is of great significance to realize a time signal merging and reading circuit that can reduce the attenuation of SiPM time signals after merging and does not introduce too much noise for taking advantage of SiPM and achieving higher temporal resolution.

发明内容SUMMARY OF THE INVENTION

鉴于以上所述现有技术的缺点,本发明的目的在于提供一种SiPM时间信号读取器,包括:信号引出模块,信号缓冲模块和信号求和模块;所述信号引出模块包括若干SiPM组成的阵列,每个所述SiPM包括两个输出端,其中第一输出端串联一检测电阻;所述第一输出端直接引出的信号作为该路SiPM输出的时间信号;所述第一输出端串联所述检测电阻后引出的信号作为第一输出信号,所述SiPM的第二输出端引出的信号作为第二输出信号;所述信号缓冲模块包括若干射频放大器;所述每路SiPM输出的时间信号被引入一个所述射频放大器;所述信号求和模块包括加法放大电路,每个所述射频放大器的输出信号被接入所述加法放大电路进行合并,所述合并后的信号作为所述SiPM阵列的时间信号。In view of the shortcomings of the above-mentioned prior art, the purpose of the present invention is to provide a SiPM time signal reader, including: a signal extraction module, a signal buffer module and a signal summing module; the signal extraction module includes a plurality of SiPM components. array, each SiPM includes two output terminals, wherein the first output terminal is connected in series with a detection resistor; the signal directly drawn by the first output terminal is used as the time signal output by the SiPM; the first output terminal is connected in series with all The signal derived from the detection resistor is used as the first output signal, and the signal derived from the second output end of the SiPM is used as the second output signal; the signal buffer module includes several radio frequency amplifiers; the time signal output by each SiPM is One of the radio frequency amplifiers is introduced; the signal summation module includes an addition amplifier circuit, the output signal of each of the radio frequency amplifiers is connected to the addition amplifier circuit for combination, and the combined signal is used as the signal of the SiPM array. time signal.

本发明还提供一种SiPM时间信号读取器,包括:信号引出模块,信号缓冲模块和信号求和模块;所述信号引出模块包括若干SiPM,每个所述SiPM包括多个SPAD,每个所述SPAD具有阴极输出端、阳极输出端,且所述SPAD的阳极输出端串联一快速输出电容,所述多个SPAD的阴极输入端并联作为该路SiPM的阴极输出端;所述多个SPAD的阳极输出端并联作为该路SiPM的阳极输出端,所述多个快速输出电容的输出端并联作为该路SiPM的快速输出端,所述时间信号由所述SiPM的快速输出端引出;所述信号缓冲模块包括若干射频放大器;每路所述时间信号被引入一个所述射频放大器;所述信号求和模块包括加法放大电路,每个所述射频放大器的输出信号被接入所述加法放大电路进行合并,所述合并后的信号作为所述SiPM时间信号。根据权利要求1所述的SiPM时间信号读取器,其特征在于,所述SiPM的输出端包括所述SiPM的阴极或阳极。The present invention also provides a SiPM time signal reader, comprising: a signal extraction module, a signal buffer module and a signal summing module; the signal extraction module includes several SiPMs, each of the SiPMs includes a plurality of SPADs, each of which The SPAD has a cathode output terminal and an anode output terminal, and the anode output terminal of the SPAD is connected in series with a fast output capacitor, and the cathode input terminals of the multiple SPADs are connected in parallel as the cathode output terminals of the SiPM; The anode output terminal is connected in parallel as the anode output terminal of the SiPM, the output terminals of the multiple fast output capacitors are connected in parallel as the fast output terminal of the SiPM, and the time signal is drawn from the fast output terminal of the SiPM; the signal The buffer module includes several radio frequency amplifiers; each channel of the time signal is introduced into one of the radio frequency amplifiers; the signal summing module includes an addition and amplification circuit, and the output signal of each of the radio frequency amplifiers is connected to the addition and amplification circuit for processing. Combined, the combined signal is used as the SiPM time signal. The SiPM time signal reader of claim 1, wherein the output terminal of the SiPM comprises a cathode or an anode of the SiPM.

优选地,上述SiPM时间信号读取器中,所述第一和/或第二输出信号接偏置电源,或接入能量读出电路,或用于定位信号来源。Preferably, in the above-mentioned SiPM time signal reader, the first and/or second output signals are connected to a bias power supply, or connected to an energy readout circuit, or used to locate the source of the signal.

优选地,上述SiPM时间信号读取器中,所述第一输出端为阴极,所述第二输出端为阳极。Preferably, in the above-mentioned SiPM time signal reader, the first output terminal is a cathode, and the second output terminal is an anode.

优选地,上述SiPM时间信号读取器中,所述第二输出端为阴极,所述第一输出端为阳极。Preferably, in the above-mentioned SiPM time signal reader, the second output terminal is a cathode, and the first output terminal is an anode.

优选地,上述SiPM时间信号读取器中,所述射频放大器的输入端设置第一电容。Preferably, in the above SiPM time signal reader, the input end of the radio frequency amplifier is provided with a first capacitor.

优选地,上述SiPM时间信号读取器中,所述射频放大器的输出端设置第二电容。Preferably, in the above SiPM time signal reader, the output end of the radio frequency amplifier is provided with a second capacitor.

优选地,上述SiPM时间信号读取器中,所述加法放大电路包括运算放大器、若干独立输入电阻和反馈电阻;每个所述射频放大器的输出信号通过一个所述输入电阻被接入所述运算放大器;所述反馈电阻Rf跨接在所述运算放大器的反相输入端和输出端之间。Preferably, in the above SiPM time signal reader, the adding and amplifying circuit includes an operational amplifier, several independent input resistors and feedback resistors; the output signal of each RF amplifier is connected to the operational amplifier through one of the input resistors amplifier; the feedback resistor Rf is connected across the inverting input terminal and the output terminal of the operational amplifier.

优选地,上述SiPM时间信号读取器中,每个所述射频放大器的输出信号通过一个所述输入电阻被接入所述运算放大器的反相输入端。Preferably, in the above-mentioned SiPM time signal reader, the output signal of each of the radio frequency amplifiers is connected to the inverting input terminal of the operational amplifier through one of the input resistors.

优选地,上述SiPM时间信号读取器中,所述运算放大器正相输入端接入一参考电压信号。Preferably, in the above-mentioned SiPM time signal reader, the non-inverting input terminal of the operational amplifier is connected to a reference voltage signal.

优选地,上述SiPM时间信号读取器中,所述阴极输出端和/或阳极输出端信号接偏置电源,或接入能量读出电路,或用于定位信号来源。Preferably, in the above SiPM time signal reader, the signal of the cathode output terminal and/or the anode output terminal is connected to a bias power supply, or connected to an energy readout circuit, or used to locate the source of the signal.

附图说明Description of drawings

图1为现有技术中SiPM的逻辑结构简图;Fig. 1 is the logical structure diagram of SiPM in the prior art;

图2为本发明第一实施方式的电路图;FIG. 2 is a circuit diagram of the first embodiment of the present invention;

图3为本发明第二实施方式的电路图;3 is a circuit diagram of a second embodiment of the present invention;

图4为本发明第三实施方式所采用的SPAD结构示意图;FIG. 4 is a schematic structural diagram of the SPAD adopted by the third embodiment of the present invention;

图5为本发明第三实施方式的电路图。FIG. 5 is a circuit diagram of a third embodiment of the present invention.

具体实施方式Detailed ways

以下通过特定的具体实例说明本发明的实施方式,本领域技术人员可由本说明书所揭露的内容轻易地了解本发明的其他优点与功效。本发明还可以通过另外不同的具体实施方式加以实施或应用,本说明书中的各项细节也可以基于不同观点与应用,在没有背离本发明的精神下进行各种修饰或改变。The embodiments of the present invention are described below through specific specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the contents disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and various details in this specification can also be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention.

图2为本发明一种实施方式的电路示意图。本发明的SiPM信号读取器包括信号引出模块1,信号缓冲模块2和信号求和模块3。信号引出模块1包括若干SiPM。每个 SiPM包括阴极端和阳极端,阳极端串联一个检测电阻Rs。阳极端直接引出的信号作为该SiPM 输出的时间信号,阳极端串联检测电阻Rs后引出的信号作为该SiPM的阳极信号,从阴极端引出的信号作为该SiPM的阴极信号。每个SiPM输出的时间信号接到信号缓冲模块2。每个 SiPM的阴极信号或阳极信号可以接偏置电源为该SiPM供电,或接入至一个能量读出电路测量该SiPM信号的能量大小。该阴极信号或阳极信号还可以用于判断信号来自阵列中哪个 SiPM。FIG. 2 is a schematic circuit diagram of an embodiment of the present invention. The SiPM signal reader of the present invention includes a signal extraction module 1 , a signal buffer module 2 and a signal summation module 3 . The signal extraction module 1 includes several SiPMs. Each SiPM includes a cathode terminal and an anode terminal, and the anode terminal is connected in series with a sense resistor Rs. The signal directly drawn from the anode terminal is used as the time signal output by the SiPM, the signal drawn from the anode terminal connected in series with the detection resistor Rs is used as the anode signal of the SiPM, and the signal drawn from the cathode terminal is used as the cathode signal of the SiPM. The time signal output by each SiPM is connected to the signal buffer module 2 . The cathode signal or anode signal of each SiPM can be connected to a bias power supply to supply power to the SiPM, or connected to an energy readout circuit to measure the energy of the SiPM signal. The cathode or anode signal can also be used to determine which SiPM in the array the signal is from.

信号缓冲模块2包括若干射频放大器21,每个SiPM输出的时间信号被独立引入一个射频放大器21,这样实现最短距离内对信号进行缓冲放大的同时,还能利用射频放大器良好的反向截止特性也能够隔离各SiPM输出信号之间的干扰,提高信号质量。为隔离信号中的直流和低频成分,并减少噪声的引入,在射频放大器21的输入端、输出端还分别设置电容C1、 C2。The signal buffer module 2 includes several radio frequency amplifiers 21, and the time signal output by each SiPM is independently introduced into one radio frequency amplifier 21, so that the signal can be buffered and amplified in the shortest distance, and the good reverse cut-off characteristic of the radio frequency amplifier can also be used. It can isolate the interference between each SiPM output signal and improve the signal quality. In order to isolate the DC and low-frequency components in the signal and reduce the introduction of noise, capacitors C1 and C2 are respectively set at the input end and the output end of the radio frequency amplifier 21 .

信号缓冲模块2缓冲后的各路SiPM信号被送入信号求和模块3。信号求和模块3包括加法放大电路,加法放大电路包括运算放大器、若干独立输入电阻Rin和反馈电阻Rf。从电容 C2输出的时间信号通过独立的输入电阻Rin连接至运算放大器的反相输入端。运算放大器的正相输入端可接地,当需要为信号提供直流偏置时,也可以输入一参考电压信号Vref。反馈电阻Rf跨接在运算放大器的反相输入端和输出端之间。各路SiPM输出的时间信号被送入加法放大电路进行合并。通过Rin和Rf的参数设置可以实现不同的放大倍数,经过合并后的信号作为SiPM陈列的时间信号。需要说明的是,从电容C2输出的时间信号通过独立的输入电阻Rin也可以连接至运算放大器的正相输入端进行同相加法合并,但相比而言,连接反相输入端为更优方案。The SiPM signals buffered by the signal buffer module 2 are sent to the signal summation module 3 . The signal summation module 3 includes an addition amplifier circuit, and the addition amplifier circuit includes an operational amplifier, several independent input resistors Rin and feedback resistors Rf. The time signal output from capacitor C2 is connected to the inverting input of the operational amplifier through a separate input resistor Rin. The non-inverting input terminal of the operational amplifier can be grounded, and a reference voltage signal Vref can also be input when a DC bias needs to be provided for the signal. The feedback resistor Rf is connected across the inverting input and output of the operational amplifier. The time signals output by each SiPM are sent to the summing and amplifying circuit for combining. Different magnifications can be achieved by setting the parameters of Rin and Rf, and the combined signal is used as the time signal of the SiPM array. It should be noted that the time signal output from the capacitor C2 can also be connected to the non-inverting input terminal of the operational amplifier through the independent input resistor Rin for in-phase addition and combination, but in comparison, it is better to connect the inverting input terminal. Program.

图3为本发明的第二实施例电路图。与图1实施例的不同之处在于,每个SiPM的阴极端串联一个检测电阻Rs,阴极端直接引出的信号作为该SiPM输出的时间信号,阴极端串联检测电阻Rs后引出的信号作为该SiPM的阳极信号,从阳极端引出的信号作为该SiPM 的阴极信号。每个SiPM输出的时间信号同样采用信号缓冲模块2进行缓冲,再将缓冲后的各路SiPM信号通过信号求和模块3进行合并与放大;每个SiPM的阴极信号或阳极信号同样可以接偏置电源为该SiPM供电,或接入至一个能量读出电路测量该SiPM信号的能量大小。也同样可以用于判断信号来自阵列中哪个SiPM。第二实施例中的信号缓冲模块2与信号求各模块3的实现方式与第一实施例相同,不再赘述。FIG. 3 is a circuit diagram of a second embodiment of the present invention. The difference from the embodiment in FIG. 1 is that the cathode terminal of each SiPM is connected in series with a detection resistor Rs, the signal directly drawn from the cathode terminal is used as the time signal output by the SiPM, and the signal drawn from the cathode terminal in series with the detection resistor Rs is used as the SiPM. The anode signal of the SiPM, the signal drawn from the anode terminal is used as the cathode signal of the SiPM. The time signal output by each SiPM is also buffered by the signal buffer module 2, and then the buffered SiPM signals are combined and amplified by the signal summation module 3; the cathode signal or anode signal of each SiPM can also be biased The power supply supplies power to the SiPM, or is connected to an energy readout circuit to measure the energy level of the SiPM signal. It can also be used to determine which SiPM in the array the signal is coming from. The implementation manner of the signal buffering module 2 and the signal obtaining modules 3 in the second embodiment is the same as that in the first embodiment, and will not be repeated here.

本发明第三实施例与前两种实施方式不同的是,SiPM中的SPAD单元结构有所不同,如图4所示。每个SPAD阳极具有一个集成的快速输出电容器,这些电容器的输出端并联作为SiPM的快速输出端,时间信号从SiPM快速输出端读取。在此实施方式中,检测电阻 Rs可以省略,每路SiPM的阳极信号和阴极信号的作用同实施例一。第三实施例的电路示意图如图5。与标准的输出模式相比,快速输出模式可以改善定时和光子计数方面的应用。第三实施例的信号缓冲模块2、信号求各模块3与前两实施例相同,不予赘述。The difference between the third embodiment of the present invention and the first two embodiments is that the structure of the SPAD unit in the SiPM is different, as shown in FIG. 4 . Each SPAD anode has an integrated fast output capacitor, the outputs of these capacitors are connected in parallel as the fast output of the SiPM, and the time signal is read from the fast output of the SiPM. In this embodiment, the detection resistor Rs can be omitted, and the functions of the anode signal and the cathode signal of each SiPM are the same as those in the first embodiment. A schematic circuit diagram of the third embodiment is shown in FIG. 5 . Fast output mode can improve timing and photon counting applications compared to standard output mode. The signal buffering module 2 and the signal obtaining modules 3 in the third embodiment are the same as those in the previous two embodiments, and will not be repeated.

综上所述,本发明的SiPM时间信号合并读出电路,与现有技术相比,在保证合并后的时间信号质量的同时,大幅减少所需的时间信号测量通道的数目,实现超大规模SiPM阵列的高性能时间信号测量,降低系统的成本和复杂度。To sum up, compared with the prior art, the SiPM time signal merging readout circuit of the present invention can greatly reduce the number of required time signal measurement channels while ensuring the quality of the merged time signal, and realize ultra-large-scale SiPM. High-performance time signal measurement of arrays, reducing system cost and complexity.

上述实施例仅例示性说明本发明的原理及其功效,而非用于限制本发明。任何熟悉此技术的人士皆可在不违背本发明的精神及范畴下,对上述实施例进行修饰或改变。The above-mentioned embodiments merely illustrate the principles and effects of the present invention, but are not intended to limit the present invention. Anyone skilled in the art can modify or change the above embodiments without departing from the spirit and scope of the present invention.

Claims (11)

1. An SiPM time signal reader, comprising:
the device comprises a signal leading-out module, a signal buffering module and a signal summing module;
the signal leading-out module comprises an array formed by a plurality of SiPMs, each SiPM comprises two output ends, and a first output end is connected with a detection resistor in series; the signal directly led out from the first output end is used as a time signal output by the SiPM; a signal led out after the first output end is connected with the detection resistor in series serves as a first output signal, and a signal led out from a second output end of the SiPM serves as a second output signal;
the signal buffer module comprises a plurality of radio frequency amplifiers; the time signal output by each SiPM is introduced into one radio frequency amplifier;
the signal summation module comprises an addition amplifying circuit, the output signal of each radio frequency amplifier is connected to the addition amplifying circuit for combination, and the combined signal is used as the time signal of the SiPM array.
2. An SiPM time signal reader, comprising:
the device comprises a signal leading-out module, a signal buffering module and a signal summing module;
the signal leading-out module comprises a plurality of SiPMs, each SiPM comprises a plurality of SPADs, each SPAD is provided with a cathode output end and an anode output end, the anode output ends of the SPADs are connected with a quick output capacitor in series, and the cathode input ends of the SPADs are connected in parallel to be used as the cathode output end of the SiPM; the anode output ends of the SPADs are connected in parallel to serve as the anode output end of the SiPM, the output ends of the rapid output capacitors are connected in parallel to serve as the rapid output end of the SiPM, and the time signal is led out from the rapid output end of the SiPM;
the signal buffer module comprises a plurality of radio frequency amplifiers; each of said time signals is introduced into one of said radio frequency amplifiers; the signal summation module comprises an addition amplifying circuit, the output signal of each radio frequency amplifier is connected to the addition amplifying circuit for combination, and the combined signal is used as the SiPM time signal. The SiPM time signal reader of claim 1, wherein an output of the SiPM comprises a cathode or an anode of the SiPM.
3. The SiPM time signal reader of claim 1, wherein the first and/or second output signal is coupled to a bias power supply, or coupled to an energy sensing circuit, or used to locate a signal source.
4. The SiPM time signal reader of claim 1, wherein the first output is a cathode and the second output is an anode.
5. The SiPM time signal reader of claim 1, wherein the second output is a cathode and the first output is an anode.
6. SiPM time signal reader according to claim 1 or 2, characterized in that the input of the radio frequency amplifier is provided with a first capacitance.
7. SiPM time signal reader according to claim 1 or 2, characterized in that the output of the radio frequency amplifier is provided with a second capacitance.
8. The SiPM time signal reader of claim 1 or 2, wherein the summing amplification circuit comprises an operational amplifier, a number of independent input resistors, and a feedback resistor; the output signal of each radio frequency amplifier is connected to the operational amplifier through one input resistor; the feedback resistor Rf is connected across the inverting input terminal and the output terminal of the operational amplifier.
9. The SiPM time signal reader of claim 8, wherein the output signal of each of the radio frequency amplifiers is coupled to the inverting input of the operational amplifier through one of the input resistors.
10. The SiPM time signal reader of claim 9, wherein a reference voltage signal is coupled to the non-inverting input of the operational amplifier.
11. The SiPM time signal reader of claim 2, wherein the cathode output and/or the anode output is signaled to a bias supply, or to an energy sensing circuit, or for locating a signal source.
CN202210653983.3A 2022-06-10 2022-06-10 SiPM time signal reader Pending CN114994739A (en)

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