CN114989244A - Bird's nest small-molecule peptide and preparation method and application thereof - Google Patents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
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Abstract
The invention discloses bird's nest small molecular peptide, which comprises bird's nest small molecular peptide, chitosan conditioner and compounding agent according to the weight ratio of (3-5) to (1) (6-9); the preparation method of the bird's nest small molecular peptide comprises the following steps: s01: the bird's nest is sent into a pulverizer to be pulverized and pass through 50-100 meshes, and then is added into 6-9 times of water to absorb water for expansion; s02: then adding 10 percent by mass of sodium hydroxide solution, adjusting the pH to 10.0, and firstly carrying out ultrasonic treatment. The bird's nest small molecular peptide is obtained by matching the small molecular peptide, the chitosan conditioner and the compound agent, the preparation method of the small molecular peptide improves the extraction efficiency of the peptide through special process treatment, and meanwhile, the chitosan is dispersed by sodium alginate through the coordination of the chitosan conditioner to improve the thorough dissolution dispersion degree of the chitosan, and after the modification coordination of the carbon nano tube composite graphene agent, the product synergizes and the functional effect of the bird's nest molecular peptide is enhanced.
Description
Technical Field
The invention relates to the technical field of peptides, and particularly relates to a bird's nest small molecular peptide and a preparation method and application thereof.
Background
The bird's nest is also called as edible bird's nest, root and vegetable, and is made up by using saliva and velvet through the processes of mixing and coagulating, and its form is similar to that of Yuyanke, and its external wall is made up by using filiform material with dense transverse strips, and piling up them into irregular prismatic projection, and its internal wall is made into irregular net form, and its bowl root is solid, and its two ends have small drop angles, and its general diameter is 6-7 cm, and depth is 3-4 cm.
The existing cubilose small molecular peptide has poor extraction rate, and meanwhile, the effect is difficult to know when the existing cubilose small molecular peptide is matched with other auxiliary agents, and further improvement treatment is needed on skin repair and moisture preservation.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a bird's nest small molecule peptide, a preparation method and application thereof, so as to solve the problems in the background technology.
The technical scheme adopted by the invention for solving the technical problems is as follows:
the invention provides bird's nest small molecular peptide which comprises a peptide body, a chitosan conditioner and a compound agent which are combined according to the weight ratio of (3-5) to (1) (6-9);
the preparation method of the peptibody comprises the following steps:
s01: feeding cubilose into a grinder, grinding the cubilose into 50-100 meshes, and then adding the cubilose into 6-9 times of water for water absorption and expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH value to 10.0, and firstly carrying out ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
Preferably, the ultrasonic power is 400-500W, and the ultrasonic time is 20-30 min.
Preferably, the preparation method of the chitosan conditioner comprises the following steps:
s11: adding 5-10 parts of chitosan into 10-20 parts of deionized water, then adding 2-4 parts of sodium alginate, stirring and mixing uniformly to obtain chitosan base solution;
s12: adding the carbon nano tube into 3-6 times of graphene modified solution, stirring for 20-30min at 55-65 ℃, wherein the stirring speed is 450-550r/min, washing and drying after stirring to obtain the carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
Preferably, the temperature of stirring and mixing of S13 is 55-65 ℃.
Preferably, the preparation method of the graphene modification liquid comprises the following steps:
adding 5-10 parts of silane coupling agent into 10-15 parts of deionized water, and then adding 1-5 parts of tartaric acid to obtain an additive;
adding 10-20 parts of graphene into 30-40 parts of sodium dodecyl sulfate solution, then adding 3-6 parts of silane coupling agent KH560 and 1-3 parts of additive, and uniformly stirring and dispersing to obtain graphene modified solution;
the inventor of the invention finds that the chitosan conditioner in the product is replaced by chitosan, the moisturizing performance of the product is obviously reduced, but the moisturizing performance of the embodiment 3 of the invention is not changed greatly and has strong persistence of the moisturizing performance, the chitosan conditioner can improve the persistence of the moisturizing performance of the product, the carbon nano tube composite graphene agent can improve the persistence of the moisturizing performance of the product, and the chitosan conditioner and the bird's nest small molecular peptide are compounded to have a synergistic effect and improve the skin care application efficiency of the product.
Preferably, the mass fraction of the modified liquid sodium dodecyl sulfate solution is 10-15%.
Preferably, the silane coupling agent is a silane coupling agent KH 550.
Preferably, the compound agent is prepared from trehalose, glycerol and water according to the weight ratio of 2:3: 6.
The invention also provides a preparation method of the bird's nest small molecular peptide, which comprises the following steps:
the method comprises the following steps: firstly, fully premixing bird's nest small molecular peptide and chitosan conditioner at the premixing rotating speed of 400-;
step two: then adding the compound agent, stirring at variable speed, continuing stirring at the rotating speed of 350-450r/min for 10-20min, and obtaining the bird's nest small molecular peptide after stirring.
The invention also provides application of the bird's nest small molecular peptide in skin care.
Compared with the prior art, the invention has the following beneficial effects:
the bird's nest small molecular peptide is obtained by matching the small molecular peptide, the chitosan conditioner and the compound agent, the preparation method of the small molecular peptide improves the extraction efficiency of the peptide through special process treatment, and meanwhile, the chitosan is dispersed by sodium alginate through the coordination of the chitosan conditioner to improve the thorough dissolution dispersion degree of the chitosan, and after the modification coordination of the carbon nano tube composite graphene agent, the product is synergistic, and the functional effect of the bird's nest molecular peptide is enhanced.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below with reference to specific embodiments, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The bird's nest small molecular peptide comprises a peptide body, a chitosan conditioner and a compound agent which are combined according to the weight ratio of (3-5) to (1) to (6-9);
the preparation method of the peptibody comprises the following steps:
s01: the bird's nest is sent into a pulverizer to be pulverized and pass through 50-100 meshes, and then is added into 6-9 times of water to absorb water for expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH value to 10.0, and firstly carrying out ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
The ultrasonic power of the embodiment is 400-500W, and the ultrasonic time is 20-30 min.
The preparation method of the chitosan conditioner of the embodiment comprises the following steps:
s11: adding 5-10 parts of chitosan into 10-20 parts of deionized water, then adding 2-4 parts of sodium alginate, stirring and mixing uniformly to obtain chitosan base solution;
s12: adding the carbon nano tube into 3-6 times of graphene modified solution, stirring for 20-30min at 55-65 ℃, wherein the stirring speed is 450-550r/min, washing and drying after stirring to obtain the carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
The temperature of stirring and mixing of S13 in this example was 55-65 ℃.
The preparation method of the graphene modification solution of the embodiment comprises the following steps:
adding 5-10 parts of silane coupling agent into 10-15 parts of deionized water, and then adding 1-5 parts of tartaric acid to obtain an additive;
adding 10-20 parts of graphene into 30-40 parts of sodium dodecyl sulfate solution, then adding 3-6 parts of silane coupling agent KH560 and 1-3 parts of additive, and uniformly stirring and dispersing to obtain graphene modified solution;
the mass fraction of the modified liquid sodium dodecyl sulfate solution in this example is 10-15%.
The silane coupling agent of the present example was a silane coupling agent KH 550.
The compound agent of the embodiment is prepared from trehalose, glycerol and water according to the weight ratio of 2:3: 6.
The preparation method of the bird's nest small molecule peptide comprises the following steps:
the method comprises the following steps: firstly, fully premixing bird's nest small molecular peptide and chitosan conditioner at the premixing rotating speed of 400-;
step two: then adding the compound agent, stirring at a variable speed, continuing stirring at the rotating speed of 350-450r/min for 10-20min, and obtaining the bird's nest small molecular peptide after the stirring is finished.
The bird's nest small molecular peptide is applied to skin care.
Example 1.
The bird's nest small molecular peptide comprises bird's nest small molecular peptide, a chitosan conditioner and a compound agent according to the weight ratio of 3:1: 6;
the preparation method of the bird's nest small molecular peptide comprises the following steps:
s01: the bird's nest is sent into a grinder to be ground and sieved by 50 meshes, and then is added into 6 times of water to absorb water for expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH value to 10.0, and firstly carrying out ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
The ultrasonic power of the present embodiment is 400W, and the ultrasonic time is 20 min.
The preparation method of the chitosan conditioner of the embodiment comprises the following steps:
s11: adding 5 parts of chitosan into 10 parts of deionized water, then adding 2 parts of sodium alginate, and stirring and mixing uniformly to obtain chitosan base solution;
s12: adding the carbon nano tube into 3 times of graphene modified solution, stirring at 55 ℃ for 20min at the stirring speed of 450r/min, washing with water, and drying to obtain a carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
The temperature of stirring and mixing of S13 in this example was 55 ℃.
The preparation method of the graphene modification solution of the embodiment comprises the following steps:
adding 5 parts of silane coupling agent into 10 parts of deionized water, and then adding 1 part of tartaric acid to obtain an additive;
adding 10 parts of graphene into 30 parts of sodium dodecyl sulfate solution, then adding 3 parts of silane coupling agent KH560 and 1 part of additive, and uniformly stirring and dispersing to obtain graphene modified solution;
the modified liquid sodium lauryl sulfate solution of this example was 10% by mass.
The silane coupling agent of the present example was a silane coupling agent KH 550.
The compound agent of the embodiment is prepared from trehalose, glycerol and water according to the weight ratio of 2:3: 6.
The preparation method of the bird's nest small molecule peptide comprises the following steps:
the method comprises the following steps: premixing small molecular peptide and chitosan conditioner of bird's nest fully at 400r/min for 25 min;
step two: then adding the compound agent, stirring at variable speed, continuing stirring at the rotating speed of 350r/min for 10min, and obtaining the bird's nest small molecular peptide after stirring.
The bird's nest small molecular peptide is applied to skin care.
Example 2.
The bird's nest small molecular peptide comprises bird's nest small molecular peptide, a chitosan conditioner and a compound agent according to the weight ratio of 5:1: 9;
the preparation method of the bird's nest small molecular peptide comprises the following steps:
s01: the bird's nest is sent into a grinder to be ground and pass through a 100-mesh screen, and then is added into 9 times of water to absorb water for expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH value to 10.0, and firstly carrying out ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
The ultrasonic power of the present embodiment is 500W, and the ultrasonic time is 30 min.
The preparation method of the chitosan conditioner of the embodiment comprises the following steps:
s11: adding 10 parts of chitosan into 20 parts of deionized water, then adding 4 parts of sodium alginate, stirring and mixing uniformly to obtain chitosan base solution;
s12: adding the carbon nano tube into 6 times of graphene modified solution, stirring for 30min at 65 ℃, wherein the stirring speed is 550r/min, washing and drying after stirring to obtain the carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
The temperature of stirring and mixing of S13 in this example was 65 ℃.
The preparation method of the graphene modification solution of the embodiment comprises the following steps:
adding 10 parts of silane coupling agent into 15 parts of deionized water, and then adding 5 parts of tartaric acid to obtain an additive;
adding 20 parts of graphene into 40 parts of sodium dodecyl sulfate solution, then adding 6 parts of silane coupling agent KH560 and 3 parts of additive, and uniformly stirring and dispersing to obtain graphene modified solution;
the modified liquid sodium lauryl sulfate solution of the present example had a mass fraction of 15%.
The silane coupling agent of the present example was a silane coupling agent KH 550.
The compound agent of the embodiment is prepared from trehalose, glycerol and water according to the weight ratio of 2:3: 6.
The preparation method of the bird's nest small molecule peptide comprises the following steps:
the method comprises the following steps: firstly, fully premixing bird's nest small molecular peptide and chitosan conditioner at the rotation speed of 500r/min for 35 min;
step two: then adding the compound agent, stirring at variable speed, continuing stirring at the rotating speed of 450r/min for 20min, and obtaining the bird's nest small molecular peptide after stirring.
The bird's nest small-molecule peptide is applied to skin care.
Example 3.
The bird's nest small molecular peptide comprises bird's nest small molecular peptide, a chitosan conditioner and a compound agent according to the weight ratio of 4:1: 8;
the preparation method of the bird's nest small molecular peptide comprises the following steps:
s01: the bird's nest is sent into a grinder to be ground into 75 meshes, and then is added into 8 times of water to absorb water for expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH value to 10.0, and firstly carrying out ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
The ultrasonic power of the present embodiment is 450W, and the ultrasonic time is 25 min.
The preparation method of the chitosan conditioner of the embodiment comprises the following steps:
s11: adding 7.5 parts of chitosan into 15 parts of deionized water, then adding 3 parts of sodium alginate, stirring and mixing uniformly to obtain chitosan base solution;
s12: adding a carbon nano tube into 4.5 times of graphene modified solution, stirring at 60 ℃ for 25min at the stirring speed of 500r/min, washing with water, and drying to obtain a carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
The temperature of stirring and mixing of S13 in this example was 60 ℃.
The preparation method of the graphene modification solution of the embodiment comprises the following steps:
adding 7.5 parts of silane coupling agent into 12.5 parts of deionized water, and then adding 3 parts of tartaric acid to obtain an additive;
adding 15 parts of graphene into 35 parts of sodium dodecyl sulfate solution, then adding 4.5 parts of silane coupling agent KH560 and 2 parts of additive, and stirring and dispersing uniformly to obtain graphene modified solution;
the modified liquid sodium lauryl sulfate solution of this example had a mass fraction of 12.5%.
The silane coupling agent of the present example was a silane coupling agent KH 550.
The compound agent of the embodiment is prepared from trehalose, glycerol and water according to the weight ratio of 2:3: 6.
The preparation method of the bird's nest small molecule peptide comprises the following steps:
the method comprises the following steps: firstly, fully premixing bird's nest small molecular peptide and chitosan conditioner at the rotation speed of 450r/min for 30 min;
step two: then adding the compound agent, stirring at variable speed, continuing stirring at the rotating speed of 400r/min for 15min, and obtaining the bird's nest small molecular peptide after stirring.
The bird's nest small molecular peptide is applied to skin care.
Comparative example 1.
Different from example 3, the bird' S nest small molecule peptide is not subjected to ultrasonic treatment in the preparation method S02.
Comparative example 2.
Unlike example 3, the chitosan conditioning agent was replaced with chitosan.
Comparative example 3.
Different from the example 3, the base liquid of the chitosan conditioner is not added with sodium alginate.
Comparative example 4.
Different from the embodiment 3, the carbon nano tube composite graphene agent is not added in the preparation of the chitosan conditioner.
Comparative example 5.
Different from the embodiment 3, the preparation of the carbon nanotube composite graphene agent adopts graphene instead.
The products of examples 1-3 and comparative examples 1-5 were subjected to a performance test;
the moisture retention rate is 1 and 5 hours after use/100% after use
The products of examples 1-3 and comparative examples 1-5 were tested for conventional performance as follows:
as can be seen from comparative examples 1-5 and example 3, after the product is tested for the moisture retention rate of 1 hour and 5 hours, the chitosan conditioner in the product is replaced by chitosan, the moisture retention performance of the product is remarkably reduced, while the moisture retention performance of the product is not greatly changed in the example 3 of the invention, the durability of the moisture retention performance is strong, the chitosan conditioner can improve the moisture retention durability of the product, the carbon nanotube composite graphene agent can improve the moisture retention durability of the product, the compounding of the chitosan conditioner and the bird's nest small molecular peptide has a synergistic effect, and the skin care application efficiency of the product is improved.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (10)
1. The bird's nest small molecular peptide is characterized by comprising a peptide body, a chitosan conditioner and a compound agent which are combined according to the weight ratio of (3-5) to (1) (6-9);
the preparation method of the peptibody comprises the following steps:
s01: the bird's nest is sent into a pulverizer to be pulverized and pass through 50-100 meshes, and then is added into 6-9 times of water to absorb water for expansion;
s02: then adding a sodium hydroxide solution with the mass fraction of 10%, adjusting the pH to 10.0, and performing ultrasonic treatment;
s03: and finally, performing microwave treatment, wherein the microwave power is 200W, the treatment time is 20min, then filtering by using an ultrafiltration membrane, and obtaining the bird's nest small molecular peptide after filtering.
2. The bird's nest small molecule peptide as claimed in claim 1, wherein the ultrasonic power is 400-500W, and the ultrasonic time is 20-30 min.
3. The bird's nest small-molecule peptide as claimed in claim 1, wherein the chitosan conditioner is prepared by the following steps:
s11: adding 5-10 parts of chitosan into 10-20 parts of deionized water, then adding 2-4 parts of sodium alginate, stirring and mixing uniformly to obtain chitosan base solution;
s12: adding the carbon nano tube into 3-6 times of graphene modified solution, stirring for 20-30min at 55-65 ℃, wherein the stirring speed is 450-550r/min, washing and drying after stirring to obtain the carbon nano tube composite graphene agent;
s13: and (3) fully stirring and mixing the chitosan base solution and the carbon nano tube composite graphene agent according to the weight ratio of 5:1 to obtain the chitosan conditioner.
4. The bird' S nest small-molecule peptide as claimed in claim 3, wherein the temperature of stirring and mixing of S13 is 55-65 ℃.
5. The bird's nest small-molecule peptide according to claim 3, characterized in that the graphene modification liquid is prepared by the following steps:
adding 5-10 parts of silane coupling agent into 10-15 parts of deionized water, and then adding 1-5 parts of tartaric acid to obtain an additive;
adding 10-20 parts of graphene into 30-40 parts of sodium dodecyl sulfate solution, then adding 3-6 parts of silane coupling agent KH560 and 1-3 parts of additive, and uniformly stirring and dispersing to obtain the graphene modified solution.
6. The bird's nest small-molecule peptide as claimed in claim 5, wherein the mass fraction of the modified liquid sodium dodecyl sulfate solution is 10-15%.
7. The bird's nest small-molecule peptide as claimed in claim 5, wherein the silane coupling agent is KH 550.
8. The bird's nest small molecule peptide as claimed in claim 1, wherein the compounding agent is prepared from trehalose, glycerol and water according to a weight ratio of 2:3: 6.
9. A method for preparing the bird's nest small molecule peptide as described in any one of claims 1-8, which comprises the following steps:
the method comprises the following steps: firstly, fully premixing bird's nest small molecular peptide and chitosan conditioner at the premixing rotating speed of 400-;
step two: then adding the compound agent, stirring at variable speed, continuing stirring at the rotating speed of 350-450r/min for 10-20min, and obtaining the bird's nest small molecular peptide after stirring.
10. Use of the bird's nest small molecule peptide of any one of claims 1-8 in skin care.
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| CN115304990A (en) * | 2022-09-07 | 2022-11-08 | 广州市佐力新材料科技有限公司 | Leather coating agent with lasting gloss and preparation method thereof |
| CN115770203A (en) * | 2022-12-13 | 2023-03-10 | 广州雅纯化妆品制造有限公司 | Modified jojoba oil and preparation method and application thereof |
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