CN114983401A - Sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient - Google Patents
Sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient Download PDFInfo
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- CN114983401A CN114983401A CN202210415348.1A CN202210415348A CN114983401A CN 114983401 A CN114983401 A CN 114983401A CN 202210415348 A CN202210415348 A CN 202210415348A CN 114983401 A CN114983401 A CN 114983401A
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- oxygen
- patient
- sensor
- body part
- partial pressure
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- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title claims abstract description 59
- 229910052760 oxygen Inorganic materials 0.000 title claims abstract description 59
- 239000001301 oxygen Substances 0.000 title claims abstract description 59
- 238000010438 heat treatment Methods 0.000 claims abstract description 42
- 238000005259 measurement Methods 0.000 claims abstract description 28
- 239000003792 electrolyte Substances 0.000 claims description 16
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 12
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 12
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 12
- 229910052737 gold Inorganic materials 0.000 claims description 12
- 239000010931 gold Substances 0.000 claims description 12
- 229910052709 silver Inorganic materials 0.000 claims description 12
- 239000004332 silver Substances 0.000 claims description 12
- 239000012528 membrane Substances 0.000 claims description 9
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 8
- 239000008280 blood Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 239000012466 permeate Substances 0.000 claims description 5
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-ZSJDYOACSA-N heavy water Substances [2H]O[2H] XLYOFNOQVPJJNP-ZSJDYOACSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 230000010287 polarization Effects 0.000 claims description 4
- 239000001103 potassium chloride Substances 0.000 claims description 4
- 235000011164 potassium chloride Nutrition 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 4
- 239000000523 sample Substances 0.000 claims description 4
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 6
- 229910002092 carbon dioxide Inorganic materials 0.000 claims 3
- 239000001569 carbon dioxide Substances 0.000 claims 2
- 238000009792 diffusion process Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 description 4
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 238000002266 amputation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000008081 blood perfusion Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000004088 microvessel Anatomy 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 208000022064 reactive hyperemia Diseases 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Optics & Photonics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention discloses a sensor for measuring the transcutaneous oxygen partial pressure of a body part of a patient, which comprises a heating element, a control unit and a temperature measuring unit, wherein the heating element is used for heating the body part of the patient to be measured and controlling the temperature of the measuring part of the body of the patient; the heating element is used for heating a body part of a patient to be measured and for controlling the temperature of the measurement part of the patient's body, a treatment sensor and a monitor are arranged in the heating element, the treatment sensor controls a control unit communicating between the treatment sensor and the monitor through signals, the control unit comprises an analog-to-digital converter, and the control unit is further adapted to control the heating element to cycle the temperature between two different temperatures at the measurement part of the patient.
Description
Technical Field
The invention relates to the technical field of medical instruments, and mainly provides a sensor for measuring the oxygen partial pressure of a patient body part through skin.
Background
The sensor for monitoring the partial pressure of oxygen in skin is used for monitoring the perfusion volume of blood in tissue and the elasticity of subcutaneous microvessels. Monitoring tissue blood perfusion amount and subcutaneous capillary elasticity, predicting diabetic microcirculation lesion and wound healing conditions through percutaneous oxygen partial pressure, determining amputation plane, monitoring indexes such as skin perfusion pressure, blocking post-reactive hyperemia (PORH) and the like.
However, the conventional sensor is heavy, light and long in measurement time, so that a new solution needs to be designed to solve the above problems.
Disclosure of Invention
Objects of the invention
The object of the present invention is to provide a sensor for measuring the transcutaneous partial pressure of oxygen in a body part of a patient, which solves the problems related to the background art mentioned above.
(II) technical scheme
In order to achieve the above object, the present invention provides a sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient, comprising a heating element, characterized in that: the heating element is used for heating a body part of a patient to be measured and for controlling the temperature of the measurement part of the patient body, a treatment sensor and a monitor are arranged in the heating element, the treatment sensor controls a control unit communicated between the treatment sensor and the monitor through signals, the control unit comprises an analog-to-digital converter, and the control unit is further suitable for controlling the heating element so as to cycle the temperature between two different temperatures at the measurement part of the patient.
Preferably, the temperature of the body part of the patient to be measured is adjusted and maintained close to the body core temperature during the first time interval; and increasing and maintaining the temperature of the body part of the patient to be measured during a second time interval such that the skin is able to permeate oxygen outwardly, from the tissue or blood to the environment, wherein the first time interval is longer than the second time interval and the sequence of the first time interval and said second time interval is repeated.
Preferably, the heating element consists of a gold electrode, a silver electrode, potassium chloride and potassium hydroxide electrolyte, and oxygen diffuses into the electrolyte through the membrane to form a measurement loop together with the gold electrode and the silver electrode.
Preferably, the heating element is composed of a gold electrode and a silver electrode which are a cathode and an anode respectively.
Preferably, when a polarization voltage of 0.2-1.5V is applied to the dissolved oxygen analyzer electrode, oxygen diffuses through the membrane, the cathode releases electrons, the anode receives electrons to generate current, and the whole reaction process is as follows: anode Ag + Cl → AgCl +2e-, cathode O2+2H2O +4e → 4 OH-.
Preferably, according to faraday's law: the current flowing through the electrode of the dissolved oxygen analyzer is in direct proportion to the oxygen partial pressure, the current and the oxygen concentration are in a linear relation under the condition of unchangeable temperature, a current voltage value is obtained, and data are obtained through acquisition of the operational amplifier circuit.
Preferably, the heating element further comprises a sensor with a measuring probe for measuring the partial pressure of the percutaneous oxygen and the CO2, a power supply, an operational amplifier circuit, a collecting circuit and a central data processing circuit.
Preferably, the cathode is sealed in the glass core, the end away from the electrode film is polished to expose the tip, the cathode and the anode are combined and placed in the electrolyte, and then the cathode and the anode are sealed by the electrode film, and oxygen penetrates through the film to react with the electrode in the electrolyte to generate current.
Preferably, the electrode membrane and retaining ring are positioned to provide sufficient contact with the patient's body part without gaps in the sides, thereby resulting in measurement errors.
Preferably, easy operation, convenient to carry to human measurement in-process, do not have other secondary damage that produce, the security is higher.
Compared with the prior art, the invention has the beneficial effects that: the heating element is used for heating a body part of a patient to be measured and for controlling the temperature of the measurement part of the patient body, a treatment sensor and a monitor are arranged in the heating element, the treatment sensor controls a control unit communicated between the treatment sensor and the monitor through signals, the control unit comprises an analog-to-digital converter, and the control unit is further suitable for controlling the heating element so as to cycle the temperature between two different temperatures at the measurement part of the patient.
Drawings
FIG. 1 is a schematic view of the internal structure of the present invention;
FIG. 2 is a schematic view of an electrode according to the present invention;
FIG. 3 is a schematic diagram of the internal flow of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be obtained by a person skilled in the art without making any creative effort based on the embodiments in the present invention, belong to the protection scope of the present invention.
Referring to fig. 1-3, the present invention provides a technical solution: a sensor for measuring transcutaneous measurement of partial pressure of oxygen at a body part of a patient, comprising a heating element, characterized in that: the heating element is used for heating a body part of a patient to be measured and for controlling the temperature of the measurement part of the patient's body, a treatment sensor and a monitor are arranged in the heating element, the treatment sensor controls a control unit communicating between the treatment sensor and the monitor through signals, the control unit comprises an analog-to-digital converter, and the control unit is further adapted to control the heating element to cycle the temperature between two different temperatures at the measurement part of the patient.
The adopted circulating temperature mode is as follows: adjusting and maintaining the temperature of the body part of the patient to be measured close to the body core temperature during a first time interval; and increasing and maintaining the temperature of the body part of the patient to be measured during a second time interval such that the skin is permeable to oxygen, oxygen permeating from the tissue or blood to the environment, wherein the first time interval is longer than the second time interval and the sequence of the first time interval and said second time interval is repeated.
The heating element consists of a gold electrode, a silver electrode, potassium chloride and potassium hydroxide electrolyte, and oxygen diffuses into the electrolyte through a membrane to form a measurement loop together with the gold electrode and the silver electrode.
The heating element is composed of a gold electrode and a silver electrode which are respectively a cathode and an anode.
When a polarization voltage of 0.2-1.5V is applied to an electrode of the dissolved oxygen analyzer, oxygen diffuses through the membrane, electrons are released from a cathode, electrons are received by an anode, current is generated, and the whole reaction process is as follows: anode Ag + Cl → AgCl +2e-, cathode O2+2H2O +4e → 4 OH-.
According to faraday's law: the current flowing through the dissolved oxygen analyzer electrode is in direct proportion to the oxygen partial pressure, the current and the oxygen concentration are in a linear relation under the condition of unchanging temperature, a current voltage value is obtained, and data are obtained through acquisition of an operational amplifier circuit.
The heating element also comprises a sensor with a transcutaneous oxygen and CO2 partial pressure measuring probe, a power supply, an operational amplifier circuit, a collecting circuit and a central data processing circuit.
The cathode is sealed in the glass core, one end of the cathode away from the electrode film is polished to expose the tip, the cathode and the anode are combined together and placed in electrolyte, then the cathode and the outside are sealed by an electrode film, and oxygen permeates through the film to react with the electrode in the electrolyte to generate current.
The electrode film and the fixing ring are in full contact with the body part of the patient, and no gap exists at the side part, so that the measurement error is caused.
The operation is simple in the aspect of use, the carrying is convenient, no other secondary damage is generated in the measurement process of the human body, and the safety is higher.
The working principle is as follows: a sensor for measuring transcutaneous oxygen partial pressure at a body part of a patient, comprising a heating element for heating the body part of the patient to be measured and for controlling the temperature at the measurement site of the patient's body, a treatment sensor and a monitor being provided in the heating element, the treatment sensor signally controlling a control unit for communication between the treatment sensor and the monitor, the control unit comprising an analog-to-digital converter, the control unit being further adapted to control the heating element to cycle the temperature between two different temperatures at the measurement site of the patient by: adjusting and maintaining the temperature of the body part of the patient to be measured close to the body core temperature during a first time interval; and during a second time interval, raising and maintaining the temperature of the body part of the patient to be measured so that the skin can permeate oxygen outwards, and the oxygen permeates to the environment from tissues or blood, wherein the first time interval is longer than the second time interval, the sequence of the first time interval and the second time interval is repeated, the heating element consists of a gold electrode, a silver electrode, potassium chloride and potassium hydroxide electrolyte, the oxygen diffuses into the electrolyte through a membrane to form a measurement loop together with the gold electrode and the silver electrode, the heating element consists of a cathode and an anode which are respectively a gold electrode and a silver electrode, when a polarization voltage of 0.2-1.5V is applied to the dissolved oxygen analyzer electrode, the oxygen diffuses through the membrane, the cathode releases electrons, and the anode receives the electrons to generate current, and the whole reaction process is as follows: anodic Ag + Cl → AgCl +2e-, cathodic O2+2H2O +4e → 4OH-, according to Faraday's law: the current and the oxygen partial pressure flowing through the dissolved oxygen analyzer electrode are in direct proportion, the current and the oxygen concentration are in a linear relation under the condition of unchanged temperature, a current voltage value is obtained, data are obtained by collecting through the operational amplifier circuit, and the heating element further comprises a sensor with a percutaneous oxygen and CO2 partial pressure measuring probe, a power supply, the operational amplifier circuit, a collecting circuit and a central data processing circuit. The negative pole is sealed in the glass core, and the polishing makes the tip expose apart from electrode film one end, in putting into electrolyte with the positive pole combination together, then form with the external world and seal with the electrode film, and oxygen sees through the film and takes place the reaction with the electrode in electrolyte and produce the electric current, and electrode film and retaining ring position need be abundant to patient's health position contact, and the lateral part does not have the gap to lead to measuring the mistake, easy operation, and convenient to carry does not have other production secondary damage to the measurement process of human body, and the security is higher.
Those not described in detail in this specification are within the skill of the art. The terms "central," "longitudinal," "lateral," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for simplicity of description only and are not intended to indicate or imply that the referenced devices or elements must be in a particular orientation, constructed and operative in a particular orientation, and are not to be considered limiting of the claimed invention.
Although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that various changes in the embodiments and/or modifications of the invention can be made, and equivalents and modifications of some features of the invention can be made without departing from the spirit and scope of the invention.
Claims (10)
1. A sensor for measuring transcutaneous measurement of partial pressure of oxygen at a body part of a patient, comprising a heating element, characterized in that: the heating element is used for heating a body part of a patient to be measured and for controlling the temperature of the measurement part of the patient body, a treatment sensor and a monitor are arranged in the heating element, the treatment sensor controls a control unit communicated between the treatment sensor and the monitor through signals, the control unit comprises an analog-to-digital converter, and the control unit is further suitable for controlling the heating element so as to cycle the temperature between two different temperatures at the measurement part of the patient.
2. A sensor for measuring transcutaneous measurement of a partial pressure of oxygen at a body part of a patient according to claim 1, wherein: the adopted circulating temperature mode is as follows: adjusting and maintaining the temperature of the body part of the patient to be measured close to the body core temperature during a first time interval; and increasing and maintaining the temperature of the body part of the patient to be measured during a second time interval such that the skin is permeable to oxygen, oxygen permeating from the tissue or blood to the environment, wherein the first time interval is longer than the second time interval and the sequence of the first time interval and said second time interval is repeated.
3. A sensor for measuring transcutaneous measurement of a partial pressure of oxygen at a body part of a patient according to claim 1, wherein: the heating element consists of a gold electrode, a silver electrode, potassium chloride and potassium hydroxide electrolyte, and oxygen enters the electrolyte through membrane diffusion to form a measurement loop together with the gold electrode and the silver electrode.
4. A sensor for measuring transcutaneous partial pressure of oxygen at a body part of a patient according to claim 1, wherein: the heating element is composed of a gold electrode and a silver electrode which are respectively a cathode and an anode.
5. A sensor for measuring transcutaneous partial pressure of oxygen at a body part of a patient according to claim 3, wherein: when a polarization voltage of 0.2-1.5V is applied to an electrode of the dissolved oxygen analyzer, oxygen diffuses through the membrane, electrons are released from a cathode, electrons are received by an anode, current is generated, and the whole reaction process is as follows: anode Ag + Cl → AgCl +2e-, cathode O2+2H2O +4e → 4 OH-.
6. A sensor for measuring transcutaneous partial pressure of oxygen at a body part of a patient according to claim 5, wherein: according to faraday's law: the current flowing through the dissolved oxygen analyzer electrode is in direct proportion to the oxygen partial pressure, the current and the oxygen concentration are in a linear relation under the condition of unchanging temperature, a current voltage value is obtained, and data are obtained through acquisition of an operational amplifier circuit.
7. A sensor for measuring transcutaneous partial pressure of oxygen at a body part of a patient according to claim 5, wherein: the heating element also comprises a sensor with a percutaneous oxygen and CO2 partial pressure measuring probe, a power supply, an operational amplifier circuit, a collecting circuit and a central data processing circuit.
8. A sensor for measuring transcutaneous partial pressure of oxygen at a body part of a patient according to claim 3, wherein: the cathode is sealed in the glass core, one end away from the electrode film is polished to expose the tip, the cathode and the anode are combined together and placed in the electrolyte, then the cathode and the outside are sealed by the electrode film, and oxygen permeates through the film to react with the electrode in the electrolyte to generate current.
9. A sensor for measuring transcutaneous partial pressure of oxygen and partial pressure of carbon dioxide at a body part of a patient according to claim 8, wherein: the electrode film and the fixing ring are in full contact with the body part of the patient, and no gap exists at the side part, so that the measurement error is caused.
10. A sensor for measuring transcutaneous partial pressure of oxygen and partial pressure of carbon dioxide at a body part of a patient according to claim 1, wherein: the operation is simple, the carrying is convenient, no other secondary damage is generated in the measurement process of the human body, and the safety is higher.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN202210415348.1A CN114983401A (en) | 2022-04-20 | 2022-04-20 | Sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient |
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CN202210415348.1A CN114983401A (en) | 2022-04-20 | 2022-04-20 | Sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient |
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CN202210415348.1A Withdrawn CN114983401A (en) | 2022-04-20 | 2022-04-20 | Sensor for measuring the transcutaneous partial pressure of oxygen at a body part of a patient |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1988849A (en) * | 2004-05-18 | 2007-06-27 | 雷迪奥米特巴塞尔股份公司 | Process for measuring partial transcutaneous co2 pressure at an ear lobe |
CN202693518U (en) * | 2012-04-13 | 2013-01-23 | 北京农业智能装备技术研究中心 | Dissolved oxygen monitoring system based on polarographic electrode |
CN105181774A (en) * | 2015-10-15 | 2015-12-23 | 中国农业大学 | Dissolved oxygen concentration measuring device and method |
CN106442680A (en) * | 2016-11-11 | 2017-02-22 | 山东省计量科学研究院 | Calibration method for portable electrochemical-process dissolved oxygen meter |
CN106535761A (en) * | 2014-07-15 | 2017-03-22 | 雷迪奥米特巴塞尔股份公司 | Intermittent measuring of the partial pressure of analyte in the skin tissue |
CN212261372U (en) * | 2020-03-27 | 2021-01-01 | 北京秋满实医疗科技有限公司 | Percutaneous oxygen partial pressure probe |
CN113588739A (en) * | 2021-06-17 | 2021-11-02 | 天津大学 | Continuous arterial blood detection system |
-
2022
- 2022-04-20 CN CN202210415348.1A patent/CN114983401A/en not_active Withdrawn
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1988849A (en) * | 2004-05-18 | 2007-06-27 | 雷迪奥米特巴塞尔股份公司 | Process for measuring partial transcutaneous co2 pressure at an ear lobe |
CN202693518U (en) * | 2012-04-13 | 2013-01-23 | 北京农业智能装备技术研究中心 | Dissolved oxygen monitoring system based on polarographic electrode |
CN106535761A (en) * | 2014-07-15 | 2017-03-22 | 雷迪奥米特巴塞尔股份公司 | Intermittent measuring of the partial pressure of analyte in the skin tissue |
CN105181774A (en) * | 2015-10-15 | 2015-12-23 | 中国农业大学 | Dissolved oxygen concentration measuring device and method |
CN106442680A (en) * | 2016-11-11 | 2017-02-22 | 山东省计量科学研究院 | Calibration method for portable electrochemical-process dissolved oxygen meter |
CN212261372U (en) * | 2020-03-27 | 2021-01-01 | 北京秋满实医疗科技有限公司 | Percutaneous oxygen partial pressure probe |
CN113588739A (en) * | 2021-06-17 | 2021-11-02 | 天津大学 | Continuous arterial blood detection system |
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Application publication date: 20220902 |