GB1422172A - Measurement of sugar concentrations - Google Patents

Measurement of sugar concentrations

Info

Publication number
GB1422172A
GB1422172A GB26473A GB26473A GB1422172A GB 1422172 A GB1422172 A GB 1422172A GB 26473 A GB26473 A GB 26473A GB 26473 A GB26473 A GB 26473A GB 1422172 A GB1422172 A GB 1422172A
Authority
GB
United Kingdom
Prior art keywords
cell
supplied
activated
liquid
voltage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB26473A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens AG
Original Assignee
Siemens AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722200119 external-priority patent/DE2200119C3/en
Application filed by Siemens AG filed Critical Siemens AG
Publication of GB1422172A publication Critical patent/GB1422172A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

1422172 Electro-chemical analysis SIEMENS AG 2 Jan 1973 [3 Jan 1972] 264/73 Heading G1N The concentration of sugar in a liquid e.g. glu- cose in blood is measured by using the liquid as an electrolyte in an electro-chemical cell. A cell comprising a platinized platinum electrode which reacts with glucose and a counter-electrode of silver or platinum is supplied with a constant current from a suitable cell through a switch and the electrochemical cell voltage is supplied, if the two cells are implanted in a patient's body, via leads extending through the patient's skin and an amplifier to an indicator. The switch may be activated by passing radiation through the skin. The cell may be supplied with a constant voltage in which case a voltage proportional to the cell current is supplied to the indicator. Alternatively the electrodes may be supplied with a constant current for a short period of time and the resulting cell voltage monitored to give the transition time of the cell which is a function of sugar concentration. In this case the leads are connected via an amplifier and threshold stages to a counter which is activated and de-activated by the signals from the threshold stages. The cells may be operated by an internal source of current in which case each cell includes three electrodes separated from each other and the liquid by partitions made of hydrophilic material (ionexchangers). The outer electrodes may consist of a silver gauze having a layer of carbon and the third electrode positioned between them of platinized platinum. The output of the cell is applied to an implanted transmitter which transmits signals to a receiver.
GB26473A 1972-01-03 1973-01-02 Measurement of sugar concentrations Expired GB1422172A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722200119 DE2200119C3 (en) 1972-01-03 Method and apparatus for measuring sugar concentration

Publications (1)

Publication Number Publication Date
GB1422172A true GB1422172A (en) 1976-01-21

Family

ID=5832247

Family Applications (1)

Application Number Title Priority Date Filing Date
GB26473A Expired GB1422172A (en) 1972-01-03 1973-01-02 Measurement of sugar concentrations

Country Status (7)

Country Link
JP (1) JPS5441358B2 (en)
AT (1) AT326835B (en)
CA (1) CA996636A (en)
CH (1) CH546406A (en)
FR (1) FR2167144A5 (en)
GB (1) GB1422172A (en)
SE (1) SE386515B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981003546A1 (en) * 1980-06-02 1981-12-10 Joslin Diabetes Center Inc Method and apparatus for determining glucose in biological fluids
US4477314A (en) * 1982-07-30 1984-10-16 Siemens Aktiengesellschaft Method for determining sugar concentration
WO2012094140A1 (en) * 2011-01-05 2012-07-12 Microchip Technology Incorporated Glucose measurement using a current source
WO2013040079A1 (en) * 2011-09-13 2013-03-21 Dose Medical Corporation Intraocular physiological sensor
US9730638B2 (en) 2013-03-13 2017-08-15 Glaukos Corporation Intraocular physiological sensor

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981003546A1 (en) * 1980-06-02 1981-12-10 Joslin Diabetes Center Inc Method and apparatus for determining glucose in biological fluids
US4340458A (en) 1980-06-02 1982-07-20 Joslin Diabetes Center, Inc. Glucose sensor
US4396464A (en) 1980-06-02 1983-08-02 Joslin Diabetes Center, Inc. Method for sensing the concentration of glucose in biological fluids
US4477314A (en) * 1982-07-30 1984-10-16 Siemens Aktiengesellschaft Method for determining sugar concentration
CN103339498A (en) * 2011-01-05 2013-10-02 密克罗奇普技术公司 Glucose measurement using a current source
WO2012094140A1 (en) * 2011-01-05 2012-07-12 Microchip Technology Incorporated Glucose measurement using a current source
CN103339498B (en) * 2011-01-05 2015-02-18 密克罗奇普技术公司 Glucose measurement using a current source
US9028661B2 (en) 2011-01-05 2015-05-12 Microchip Technology Incorporated Glucose measurement using a current source
WO2013040079A1 (en) * 2011-09-13 2013-03-21 Dose Medical Corporation Intraocular physiological sensor
EP3659495A1 (en) * 2011-09-13 2020-06-03 Dose Medical Corporation Intraocular physiological sensor
US11363951B2 (en) 2011-09-13 2022-06-21 Glaukos Corporation Intraocular physiological sensor
US11564569B2 (en) 2011-09-13 2023-01-31 Glaukos Corporation Intraocular physiological sensor
US9730638B2 (en) 2013-03-13 2017-08-15 Glaukos Corporation Intraocular physiological sensor
US10849558B2 (en) 2013-03-13 2020-12-01 Glaukos Corporation Intraocular physiological sensor

Also Published As

Publication number Publication date
ATA962772A (en) 1975-03-15
SE386515B (en) 1976-08-09
DE2200119A1 (en) 1973-07-12
DE2200119B2 (en) 1977-02-10
CA996636A (en) 1976-09-07
JPS4879695A (en) 1973-10-25
AT326835B (en) 1975-12-29
CH546406A (en) 1974-02-28
FR2167144A5 (en) 1973-08-17
JPS5441358B2 (en) 1979-12-07

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee