CN114917433B - Pulmonary administration atomizing device - Google Patents

Pulmonary administration atomizing device Download PDF

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Publication number
CN114917433B
CN114917433B CN202210492135.9A CN202210492135A CN114917433B CN 114917433 B CN114917433 B CN 114917433B CN 202210492135 A CN202210492135 A CN 202210492135A CN 114917433 B CN114917433 B CN 114917433B
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China
Prior art keywords
bottle body
expansion
bottle
fluid
base
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CN202210492135.9A
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Chinese (zh)
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CN114917433A (en
Inventor
张建辉
王嘉龙
谭天
谢堂
温雨欣
陈伯川
梁家丽
曾耀华
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Guangzhou University
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Guangzhou University
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Publication of CN114917433A publication Critical patent/CN114917433A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10Devices using liquid inhalable precursors
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24FSMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40Constructional details, e.g. connection of cartridges and battery parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament

Abstract

The invention provides a pulmonary administration atomizing device, which relates to the technical field of atomizers and comprises: a base containing a medium fluid therein; an ultrasonic transducer fixed in the base and coated by the dielectric fluid; the bottle body is detachably arranged on the base, the inside of the bottle body is filled with atomized fluid, and the outside of the bottle body is in contact with the medium fluid; the expansion and contraction cover body is provided with an expansion and contraction structure and is communicated with the inside of the bottle body in a sealing way. According to the invention, the medium fluid is utilized to transfer the high-frequency oscillation of the ultrasonic transducer to the base, so that the connection structure of the atomizer is simplified, and the atomizer is convenient to transport and carry; the atomized fluid is directly atomized in the bottle body, so that the atomization flow is simplified, and the preparation of the atomized gas is more convenient; the pressure in the bottle is adjusted at any time through expanding and contracting the cover body so as to adjust the spraying strength, thereby leading the feeling to be better during inhalation.

Description

Pulmonary administration atomizing device
Technical Field
The invention relates to the technical field of atomizers, in particular to a pulmonary administration atomizing device.
Background
Atomizers are increasingly used in the production and life of people. For example, in the medical field, when vaccinating against new coronaries and other respiratory diseases, the injection method is not friendly to young people or hemophilia patients, and can be used for treatment by inhalation after atomizing the vaccine/drug; in the field of daily life, electronic cigarettes are gradually becoming new trends to replace traditional cigarettes, and the electronic cigarettes are also an atomizer device for atomizing tobacco tar and then inhaling the tobacco tar.
The principle of the atomizer on the market at present mainly is that high-frequency electronic oscillation is applied through a porous atomization net or high-frequency mechanical oscillation, such as a piezoelectric ceramic atomization sheet, and high-frequency resonance is generated through the reverse pressure effect of the piezoelectric ceramic to break up a liquid molecular structure, so that water mist with the diameter nano-scale size is formed, and then the water mist is pressurized and injected into a bottle for use. The prior art mainly has the following problems:
(1) the high-frequency oscillation device and the atomization container are required to be integrally connected and closely contacted for excitation, so that the structural complexity and the space volume of the atomizer are increased, and the atomizer is inconvenient to transport and carry;
(2) the liquid is atomized and then the mist is filled into the bottle, so that the use is inconvenient;
(3) along with the change of the stock of the atomized gas in the bottle, the pressure in the bottle changes along with the change, the spray intensity is too high when the atomized gas is too much, and the spray intensity is too low when the atomized gas is too little, so that inhalation discomfort is caused.
Disclosure of Invention
The invention aims to provide a pulmonary administration atomizing device which can enhance portability of an atomizer, is convenient to use and has controllable spray strength;
the present invention provides a pulmonary drug delivery nebulizing device comprising: a base containing a medium fluid therein; an ultrasonic transducer fixed in the base and coated by the dielectric fluid; the bottle body is detachably arranged on the base, the inside of the bottle body is filled with atomized fluid, and the outside of the bottle body is in contact with the medium fluid; the expansion and contraction cover body is provided with an expansion and contraction structure and is communicated with the inside of the bottle body in a sealing way.
Further, the expansion cover body comprises a flexible ridge and an opening plate, one end of the opening plate is rotatably connected with the bottle body through the flexible ridge, and the side face of the opening plate is connected with the bottle body through a spring page.
Further, a jack is formed in the flexible ridge, and a sealing piece is connected to the jack and used for keeping sealing after the jack is inserted.
Further, a syringe is also included, the syringe being insertable into the receptacle to inject the atomizing fluid.
Further, the device also comprises a mist absorber, and the mist absorber can be inserted into the jack for absorbing mist by a user.
Further, the opening and closing plate is connected with the bottle body through a rolling device, and the rolling device is used for controlling the opening and closing plate to overturn around the flexible ridge.
Further, a pressure sensor is arranged in the bottle body, the roller shutter device comprises a motor and a control system, and the pressure sensor and the motor are both connected with the control system.
Further, a hook groove is formed in the opening plate, a drag hook is connected to the motor, and the drag hook is mounted on the hook groove.
Further, the base is provided with a plurality of bottle bodies.
Further, the base comprises a containing groove, the ultrasonic transducer is fixed at the bottom of the containing groove, the medium fluid is contained in the containing groove, and a flange for bearing the bottle body is arranged on the inner wall of the containing groove.
According to the technical scheme, the medium fluid is utilized to transfer the high-frequency oscillation of the ultrasonic transducer to the base, so that the connection structure of the atomizer is simplified, and the atomizer is convenient to transport and carry; the atomized fluid is directly atomized in the bottle body, so that the atomization flow is simplified, and the preparation of the atomized gas is more convenient; the pressure in the bottle is adjusted at any time through expanding and contracting the cover body so as to adjust the spraying strength, thereby leading the feeling to be better during inhalation.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings that are needed in the description of the embodiments or the prior art will be briefly described, and it is obvious that the drawings in the description below are some embodiments of the present invention, and other drawings can be obtained according to the drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic diagram of the pre-atomization state of the present invention;
FIG. 2 is a schematic illustration of the present invention in an atomized state;
FIG. 3 is a schematic view of the atomized state according to the present invention;
FIG. 4 is a schematic illustration of the fluid state of the injected medium prior to atomization in accordance with the present invention;
FIG. 5 is a schematic view showing the state of inhalation of atomized particles after atomization according to the present invention;
FIG. 6 is a schematic view showing a recovery state of the expansion and contraction cover body of the present invention;
FIG. 7 is a schematic view of the expansion and contraction cover of the present invention in an expanded state;
FIG. 8 is a schematic diagram of the position of a pressure sensor according to the present invention;
reference numerals illustrate:
1-base, 101-flange
2-ultrasonic transducer and 3-bottle
4-expansion and contraction cover body, 401-flexible ridge, 402-opening plate, 403-spring page and 404-sealing sheet
5-Medium fluid,
6-atomizing fluid, 601-atomizing particles
7-syringe and 8-mist absorber
9-roller blind device, 901-pressure sensor, 902-draw hook, 903-hook slot
Detailed Description
The technical solutions of the present invention will be clearly and completely described in connection with the embodiments, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more of the described features. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise. Furthermore, the terms "mounted," "connected," "coupled," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Example 1
Specifically, this example 1 will be described by taking a new coronal vaccine inhaled through the lung as an example.
As shown in fig. 1-3, the present invention provides a pulmonary drug delivery aerosolization device comprising: a base 1, wherein the base 1 is filled with medium fluid 5; an ultrasonic transducer 2 fixed in the base 1 and covered by a dielectric fluid 5; the bottle body 3 is detachably arranged on the base 1, the inside of the bottle body is filled with atomized fluid 6, and the outside of the bottle body is contacted with medium fluid 5; the expansion and contraction cover body 4 has an expansion and contraction structure and is communicated with the interior of the bottle body 3 in a sealing way.
In the initial stage of the preparation of the atomizer as shown in fig. 1. The ultrasonic transducer 2 is fixed on the base 1, and the base 1 is filled with a proper amount of medium fluid 5. Because the dielectric fluid 5 is required to carry the mechanical energy generated by the transfer ultrasound transducer 2, the fluid level of the dielectric fluid 5 is at least higher than the fluid level of the new crown vaccine in the vial 3 while completely submerging the ultrasound transducer 2. The bottle body 3 is placed on the base 1, and the base 1 can be additionally provided with a retainer, so that the position of the bottle body 3 is relatively fixed, and the bottle body is prevented from floating, drifting away or toppling over. After the bottle body 3 is placed, the power supply of the ultrasonic transducer 2 can be connected to start atomization;
as shown in fig. 2 during the atomizer operation. After the ultrasonic transducer 2 is powered on, vibration is generated, and the vibration is transmitted to the bottle body 3 through the medium fluid 5, so that the new crown vaccine in the bottle body 3 is atomized, and atomized particles 601 are formed. Along with the increasing of the quantity of the atomized particles 601, the pressure in the bottle rises, and the expansion and contraction cover body 4 expands along with the rising, so that the pressure in the bottle body 3 is kept stable, the overlarge flow during inhalation is avoided, the atomized particles 601 are uniformly distributed in the bottle body 3, the problem that the atomized particles 601 are mainly concentrated at the bottom in an atomization device with an unchangeable volume can be avoided, and the atomization efficiency is effectively improved. When the atomization of the new crown vaccine in the bottle is completed, the power supply of the ultrasonic transducer 2 is cut off to form a state shown in fig. 3, and the atomization process is finished.
In the present invention, the bottle 3 should have good ability to transmit vibration; the cross-sectional shape of the bottle 3 includes, but is not limited to, circular, elliptical, polygonal, or other fitting shape that facilitates the transfer of vibrations, etc.; the material of the bottle body 3 includes, but is not limited to, plastic, metal, glass, and the like. The bottle body 3 is stably placed on the base 1 or is fixed on the base 1 through a fastening device; the level of the atomizing fluid 6 in the bottle 3 should always be equal to or lower than the level of the medium fluid 5 in the base 1.
In the present invention, the medium fluid 5 should have a function of transmitting mechanical energy generated by the ultrasonic transducer 2 and conducting the mechanical energy to the bottle 3. Including but not limited to water and organic solvents such as alcohols, ethers, esters, ketones, etc., and specifically can be any one of a viscous semisolid preparation made of purified water, medical alcohol, sodium alginate solution, sodium carboxymethyl cellulose solution, carbomer solution, glycerin, and a viscous semisolid preparation made of propylene glycol.
In the present invention, the ultrasonic transducer 2 is connected to an external power source and rigidly connected to the base 1, preferably by gluing, including, but not limited to, gluing, welding, embedding, integrally molding, etc. The ultrasonic transducer 2 includes, but is not limited to, a piezoelectric ultrasonic transducer 2. The piezoelectric ultrasonic transducer 2 applies high-frequency electronic oscillation to the piezoelectric ceramic atomizing sheet, and generates high-frequency resonance through the inverse pressure effect of the piezoelectric ceramic to break up the liquid molecular structure, so that water mist with the diameter of nanometer grade is formed, liquid medicine or essential oil can be effectively dispersed into the air, and the ultrasonic transducer 2 belongs to a commercially available finished product in the prior art, and is not repeated.
In the present invention, the function of the expansion and contraction cover 4 is mainly to make the volume space of the bottle 3 variable. Can be realized through a foldable structure (such as a corrugated pipe, a folding plate and the like), or can be realized through a telescopic structure (such as a telescopic plate and the like which can be drawn and extended), or can be realized through the characteristics of the material (such as an elastic rubber film and the like), and the detailed description is omitted. The bottle body 3 can be provided with a sealing gasket when connected with the expansion cover body 4.
In the present invention, the new crown vaccine is exemplified as the atomizing fluid 6, but it should be noted that the atomizing fluid 6 may be various liquid substances required to be atomized, such as inhalation vaccine, inhalation medicine, e-cigarette tobacco tar, aromatic essential oil, coffee essential oil, alcohol, etc.; and may contain fluids that assist in atomization, such as low viscosity fluids, organic solvents, and the like.
Example 2
Specifically, embodiment 2 provides a specific structure of the expansion and contraction cover 4.
As shown in fig. 4 to 7, the expansion and contraction cover 4 includes a flexible ridge 401 and an opening and closing plate 402, one end of the opening and closing plate 402 is rotatably connected with the bottle 3 through the flexible ridge 401, and a side surface of the opening and closing plate 402 is connected with the bottle 3 through a spring leaf 403.
The flexible ridge 401 is specifically a connecting sheet with rebound capability, for example, a flexible plastic sheet, which is located at one end of the top opening of the bottle body 3 and is in sealing connection with the bottle body 3, while one end of the opening and closing plate 402 is in sealing connection with the flexible ridge 401, that is, the flexible ridge 401 is integrally connected with the opening and closing plate 402 and the bottle body 3, the connection modes include, but are not limited to, bonding, thermoplastic, stamping connection and other connection modes, the side ends of the spring pages 403 are embedded inside the flexible ridge 401, and the air tightness of the atomizing bottle can be ensured at the position by dripping solid soluble polymers such as EVA hot melt adhesive and the like. The other end of the opening and closing plate 402 can be turned around the flexible ridge 401 (the maximum rotation angle is preferably 90 degrees) due to the rebound ability of the flexible ridge 401, and the spring pages 403 expand or retract accordingly during the turning process of the opening and closing plate 402, so that the expansion and contraction cover 4 has the expansion and contraction function, and the volume of the bottle body 3 is adjusted. The spring leaf 403 includes a foldable structure formed by a plurality of blades, and can perform telescopic change, the telescopic path is a section of arc, and certain coaxiality is kept between the telescopic path and the opening and closing plate 402, and the telescopic change is performed while the telescopic change is continuously kept relative to the bottle 3. The specific number of blades includes, but is not limited to, ten layers; the material is plastic, and the material selection includes, but is not limited to, plastic, rubber, paper and the like, and can mainly play a sealing effect.
Example 3
Specifically, this embodiment 3 describes a mist absorbing structure of the mist absorber 8.
As shown in fig. 4-5, the flexible ridge 401 is provided with a receptacle (not shown) to which a sealing piece 404 is attached, the sealing piece 404 being used to maintain a seal after the receptacle is inserted. Also included is a syringe 7, the syringe 7 being insertable into the receptacle for injecting the atomizing fluid 6. Further comprises a mist absorber 8, and the mist absorber 8 can be inserted into the jack for absorbing mist by a user.
After the atomization is completed, the bottle body 3 is removed from the base 1, and as shown in fig. 7, the spring leaf 403 is in an expanded state, and the bottle is filled with new crown vaccine atomized particles 601. Due to gravity, the atomized particles 601 in the bottle 3 naturally have a lower concentration in the upper layer and a higher concentration in the lower layer, but generally fill the entire bottle 3. The atomizing bottle after atomization can be used immediately or used in other time and places after refrigeration and transportation. When in use, the inside of the bottle body 3 exchanges substances with the outside through the jack. The sealing piece 404 is arranged on the jack in a sealing way, and before atomization, the injector 7 is inserted into the sealing piece 404 to inject atomized fluid 6 into the bottle body 3; during the atomization process, the sealing piece 404 is pulled out, and the sealing piece 404 is closed again, so that the sealing environment is kept in the bottle body 3; after the atomization is completed, the mist absorber 8 is inserted into the sealing sheet 404 to inhale the atomized particles 601. The material of the sealing sheet 404 includes, but is not limited to, plastic, metal, paper, etc., and can be closely abutted against the syringe 7 and the mist absorber 8 after being inserted, and the sealing property is maintained. The sealing sheet 404 is attached to the flexible ridge 401 with good sealing properties, including but not limited to adhesive bonding, thermoplastic, punch forming attachment, etc. The mist absorber 8 specifically includes a cannula for insertion into the sealing plate 404 and a mist absorbing mask for use by a user to absorb mist.
In the process of inoculating the new crown vaccine, as shown in fig. 7, after the mist absorber 8 breaks the sealing sheet 404, the opening plate 402 is pressed to turn downwards, the spring pages 403 are contracted in the process of turning downwards, and the compressed air pressure in the bottle is increased, so that the new crown vaccine atomized particles 601 are ejected from the mist absorbing mask, and the new crown vaccine atomized particles 601 can enter the lungs of an inoculated person, thereby completing the inoculation process. By controlling the pressing speed of the opening plate 402, the flow rate of the spray of the new crown vaccine atomized particles 601 can be controlled, and even if the bottle body 3 uses a more stable hard material, the new crown vaccine atomized particles 601 in the bottle can be easily discharged out of the bottle body 3 in a large amount and uniformly.
When the opening plate 402 is flipped back down by 0 degrees, the inoculation process is completed. At this time, the form of the expansion and contraction cover 4 is as shown in fig. 6, the space in the bottle reaches the minimum, and most of the atomized particles 601 are discharged. The fog inhalation is used as a disposable product and is discarded according to medical waste, the structures of the bottle body 3 and the expansion cover body 4 can be recycled after being recovered, and the base 1 and the ultrasonic transducer 2 can be directly reused. The whole device has high recycling rate, and is clean and environment-friendly.
Example 4
Specifically, this embodiment 4 describes a control structure of the expansion and contraction cover 4.
As shown in fig. 4-8, the opening plate 402 is connected with the bottle body 3 through a rolling device 9, and the rolling device 9 is used for controlling the opening plate 402 to turn around the flexible ridge 401. The bottle body 3 is internally provided with a pressure sensor 901, and the roller shutter device 9 comprises a motor (not shown) and a control system (not shown), and the pressure sensor 901 and the motor are connected with the control system. The opening plate 402 is provided with a hook groove 903, the motor is connected with a draw hook 902, and the draw hook 902 is mounted on the hook groove 903.
In the atomization process, the pressure sensor 901 detects that the pressure in the bottle body 3 is higher than a set value, namely, an electric signal is transmitted to the control system, the control system controls the motor to act after receiving the signal, so that the motor recovers the draw hook 902, the draw hook 902 pulls the opening plate 402 to turn upwards through the embedded hook groove 903, the spring page 403 stretches and expands accordingly, the expansion and contraction cover body 4 expands, and the capacity of an atomization bottle formed by the expansion and contraction cover body 4 and the bottle body 3 increases until the pressure reaches a preset value. Otherwise, the pressure sensor 901 detects that the pressure in the bottle body 3 is smaller than a set value, and the motor releases the draw hook 902, so that the expansion and contraction cover body 4 is contracted, the capacity of the atomizing bottle formed by the expansion and contraction cover body 4 and the bottle body 3 is reduced, and the pressure reaches a preset value.
In order to reduce the cost of use, the roller shutter device 9 can be removed when the vials 3 need to be sterilized or replaced, and can be installed on a sterilized vial 3 or another unused entirely new vial 3 in mounted connection with a new shutter 402. The motor can be externally connected with a power supply or provided with a battery system for supplying power.
Example 5
In particular, for example, in the field of electronic aerosol, it is often necessary to atomize and mix multiple raw materials to manufacture electronic cigarette products with different tastes, but a single atomizer can only add one liquid to be atomized at the same time, so that a plurality of liquids with different components cannot be atomized at the same time, which causes inconvenience. This example 5 describes a structure in which a plurality of bottles 3 are simultaneously atomized.
The base 1 is provided with a plurality of bottle bodies 3. The base 1 comprises a containing groove, the ultrasonic transducer 2 is fixed at the bottom of the containing groove, the medium fluid 5 is contained in the containing groove, and a flange 101 for bearing the bottle body 3 is arranged on the inner wall of the containing groove.
Taking the electronic cigarette atomization process as an example, various different raw materials are respectively injected into different bottle bodies 3, and then the bottle bodies 3 are jointly placed on the base 1, and as the electronic cigarette atomization device performs vibration transmission through the medium fluid 5, other connecting structures are not required to be arranged to realize vibration, and the manufacturing cost is reduced. When the ultrasonic transducer 2 is started, different atomization fluids 6 in all the bottle bodies 3 on the base 1 are synchronously atomized, and atomized particles 601 in each bottle body 3 are mixed and inhaled after atomization, so that the electronic cigarette with mixed taste can be achieved. The supply speed of the atomized particles 601 of each raw material can be independently controlled by controlling the turning degree of the opening and closing plate 402 on different bottle bodies 3, respectively, so as to adjust the different tastes of the mixed atomized particles 601.
The application principle of the invention is as follows:
when the atomizing device is required to be used, the fluid 6 to be atomized is pre-stored in the bottle body 3 or the fluid 6 to be atomized is injected into the bottle body 3 through the injector 7, the bottle body 3 is placed on the base 1 to be in contact with the medium fluid 5, the ultrasonic transducer 2 is started, and vibration energy is transmitted through the medium fluid 5, so that atomization can be performed. The volume of the interior of the bottle body 3 is controlled by expanding and contracting the cover body 4 in the atomization process; after atomization is completed, the mist absorber 8 is inserted into the sealing sheet 404 to absorb mist, and the spraying force of atomized particles 601 can be controlled by pressing the opening plate 402.
Other advantages of the invention:
the fluid 6 to be atomized before atomization can be packaged in the bottle body 3, so that the transportation and the storage are convenient; or the fluid 6 to be atomized is injected into the bottle body 3 through the injector 7, so that the controllability is higher.
The mist outlet amount can be adjusted by changing the expansion and contraction of the expansion and contraction cover body 4; due to the expansion and contraction of the spring pages 403 during atomization, the air pressure in the bottle body 3 is always in a dynamic stable state, the volume in the bottle body 3 is increased from small, the density gradient distribution of atomized particles 601 is uniform, and the layering effect of the lower layer with mist and the upper layer without mist can not occur.
When in atomization, a plurality of bottle bodies 3 can be simultaneously placed on one base 1, and various liquids with different components can be simultaneously atomized in different bottles, so that a plurality of bottle mist can be produced in the same time, and the atomization efficiency is greatly improved; packaging the atomized single bottle, and ensuring that the quality of the atomized mist is not influenced by the environment; each bottle of fog is independently packaged, and different bottles are supplied for different users for use, so that the bottle is clean and sanitary.
When the opening plate 402 is pressed down, the spring pages 403 are driven to contract, mist is sprayed out of the mist absorber 8 through the increase of air pressure, the process that a user sucks air forcefully is omitted, the mist in the bottle body 3 can be discharged more fully after being compressed, and the waste of the residual mist is reduced.
Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and not for limiting the same; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the invention.

Claims (7)

1. A pulmonary delivery aerosolization device, comprising:
a base containing a medium fluid therein;
an ultrasonic transducer fixed in the base and coated by the dielectric fluid;
the bottle body is detachably arranged on the base, the inside of the bottle body is filled with atomized fluid, and the outside of the bottle body is in contact with the medium fluid;
the expansion and contraction cover body is provided with an expansion and contraction structure and is in sealing communication with the interior of the bottle body, the expansion and contraction cover body comprises a flexible ridge and an opening plate, one end of the opening plate is rotationally connected with the bottle body through the flexible ridge, the side surface of the opening plate is connected with the bottle body through a spring page, and the volume of the interior of the bottle body is controlled through expansion and contraction of the expansion and contraction cover body in the atomization process; after atomization is completed, the spraying force of atomized particles is controlled by pressing the opening and closing plate;
the roller shutter device is used for controlling the roller shutter plate to overturn around the flexible ridge, a pressure sensor is arranged in the bottle body, the roller shutter device comprises a motor and a control system, and the pressure sensor and the motor are both connected with the control system; in the atomization process, the pressure sensor detects that the pressure in the bottle body is larger than a set value, namely an electric signal is transmitted to the control system, the control system controls the motor to act after receiving the signal, so that the expansion and contraction cover body expands, the capacity of an atomization bottle formed by the expansion and contraction cover body and the bottle body increases until the pressure reaches a preset value; otherwise, the pressure sensor detects that the pressure in the bottle body is smaller than a set value, namely an electric signal is transmitted to the control system, the control system controls the motor to act after receiving the signal, so that the expansion and contraction cover body is contracted, the capacity of the atomizing bottle formed by the expansion and contraction cover body and the bottle body is reduced, and the pressure reaches a preset value.
2. The pulmonary drug delivery aerosolization device of claim 1, wherein the flexible ridge defines a receptacle, the receptacle having a sealing tab attached thereto, the sealing tab adapted to remain sealed after the receptacle is inserted.
3. The pulmonary delivery aerosolization device of claim 2, further comprising a syringe insertable into the receptacle to inject the aerosolized fluid.
4. The pulmonary drug delivery aerosolization device of claim 2, further comprising a mist aspirator insertable into the receptacle for inhalation by a user.
5. The pulmonary drug delivery atomizing device according to claim 1, wherein the opening plate is provided with a hook groove, the motor is connected with a drag hook, and the drag hook is mounted on the hook groove.
6. The pulmonary drug delivery aerosolization device of claim 1, wherein the base has a plurality of the vials disposed thereon.
7. The pulmonary drug delivery aerosolizing device of claim 6, wherein the base includes a receiving slot, the ultrasonic transducer is secured to a bottom of the receiving slot, the medium fluid is contained within the receiving slot, and a flange is provided on an inner wall of the receiving slot that carries the vial.
CN202210492135.9A 2022-05-07 2022-05-07 Pulmonary administration atomizing device Active CN114917433B (en)

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CN202210492135.9A CN114917433B (en) 2022-05-07 2022-05-07 Pulmonary administration atomizing device

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101351274A (en) * 2005-12-30 2009-01-21 3M创新有限公司 Liquid supply assembly and liquid spray apparatus
CN105173046A (en) * 2015-07-17 2015-12-23 哈尔滨工程大学 Accordion type ship propeller
CN114404746A (en) * 2022-02-28 2022-04-29 广州大学 Portable atomizing device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101351274A (en) * 2005-12-30 2009-01-21 3M创新有限公司 Liquid supply assembly and liquid spray apparatus
CN105173046A (en) * 2015-07-17 2015-12-23 哈尔滨工程大学 Accordion type ship propeller
CN114404746A (en) * 2022-02-28 2022-04-29 广州大学 Portable atomizing device

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