CN114904145A

CN114904145A - Wound treatment system

Info

Publication number: CN114904145A
Application number: CN202110176643.1A
Authority: CN
Inventors: 林志隆; 郑丰庆; 赵士维
Original assignee: BenQ Materials Corp
Current assignee: BenQ Materials Corp
Priority date: 2021-02-09
Filing date: 2021-02-09
Publication date: 2022-08-16

Abstract

The invention relates to a wound treatment system, which comprises a wound dressing, a negative pressure source, a light-emitting device, an image identification module and a control module. The wound dressing comprises a shell with an opening, and a barrier layer with a tubular passage separates the interior of the shell from the opening to form a containing space. A negative pressure source is fluidly connected to the wound dressing to remove interstitial fluid from the wound. The light-emitting device is arranged in the accommodating space and is optically coupled with the blocking layer, and can emit light rays with different wave bands to serve as detection light rays required by the image identification module arranged on one side of the opening of the wound dressing shell and provide specific phototherapy wavelengths required by different stages of the wound. After the operation and judgment of the control module, the auxiliary healing environment with phototherapy wavelength and proper negative pressure required by wounds in different stages can be automatically provided.

Description

Wound treatment system

Technical Field

The invention relates to a treatment system for chronic wounds, which has the effect of forming phototherapy and negative pressure treatment environments with different wavelengths at the wounds aiming at different recovery stages of the chronic wounds.

Background

Natural healing of wounds in the body is a complex process that begins to function from the time of injury. Generally, it can be divided into four stages of hemostasis, inflammation, hyperplasia and remodeling. During the hemostasis phase, the body minimizes injury by delivering proteins and other clotting substances to the wound via the blood flow, and forms a blood clot to prevent blood loss. During the inflammatory phase, the immune system resists the invasion of foreign bacteria and microbes, and leukocytes phagocytose the bacteria and debris of the injured area, resulting in a slightly red, swollen, hot, painful inflammatory response. Finally, the regeneration stage of the proliferation of the microvascular and granulation tissues and the remodeling stage of the skin tissues with closed healing are entered.

However, chronic wounds such as diabetic wounds, pressure sores or ulcers resulting from poor peripheral circulation often do not heal in a predetermined period of time, but instead are repeatedly infected between the inflammatory and proliferative stages, making it difficult to heal into the subsequent remodeling stage. For treating such chronic wounds, it is known to remove excess tissue fluid by creating a negative pressure environment at the wound site, and refer to fig. 1, which is a schematic view of a wound dressing 1 for a negative pressure treatment system, the wound dressing 1 comprising a wound contact layer 12 for covering a wound 15; an absorbent layer 13 for absorbing interstitial fluid generated from the wound 15; and a water-blocking layer 14 coated outside the absorption layer 13 to prevent tissue fluid from penetrating and contacting with the outside. And is in fluid communication with a negative pressure source (not shown) via a conduit 11 to deliver negative pressure to the wound dressing 1 and to absorb excess tissue fluid to maintain the wound in a desired moist environment without infiltration. However, even under the negative pressure environment and the covering of the dressing, the sterile environment of the chronic wound can not be maintained, so the patient's autoimmunity or the application of antibiotics to inhibit the invasion of bacteria are required, and in order to maintain the necessary moist environment, the nutrients in the tissue fluid can also promote the growth of microorganisms, which affects the wound healing process. Therefore, it is preferable to have additional means for inhibiting bacteria and increasing the efficiency of cell proliferation.

Therefore, the inventor of the present invention provides a wound treatment system, which can combine the modes of negative pressure therapy and phototherapy, and automatically adjust and control the negative pressure and the irradiation wavelength of a chronic wound that is not easy to heal according to the stage of the chronic wound, so as to further help the wound heal.

Disclosure of Invention

In view of the above problems of the prior art, the present invention provides a wound treatment system with novelty, creativity and practicability to overcome the difficulties of the existing products.

To achieve the above object, in one embodiment, the wound treatment system includes: the wound dressing comprises a shell with an opening, a wound contact layer arranged on the opening to cover a wound, and a barrier layer for separating the interior of the shell and the wound contact layer at the opening to form a containing space; wherein, the barrier layer comprises at least one tubular channel, one nozzle of the tubular channel is positioned at the side of the containing space, and the other nozzle of the tubular channel is positioned at the side of the wound contact layer; a negative pressure source comprising a negative pressure delivery conduit in fluid communication with the receiving space of the wound dressing housing for applying a negative pressure to the wound via the negative pressure delivery conduit such that interstitial fluid exuded from the wound can permeate through the wound contact layer and pass through the tubular passage to the receiving space; a light emitting device disposed in the receiving space of the wound dressing, optically coupled to the barrier layer, and capable of emitting a first band light and a second band light; the image identification module is arranged on one side of the opening of the wound dressing shell and used for receiving the image light rays reflected by the wound irradiated by the light-emitting device; and the control module is electrically connected with the negative pressure source, the light-emitting device and the image identification module.

In another embodiment of the wound treatment system, the receiving space of the wound dressing comprises an absorbent layer, and the negative pressure delivery conduit further comprises a water-blocking and air-permeable layer to prevent tissue fluid from entering the negative pressure source.

In another embodiment of the wound treatment system, a liquid storage device is further disposed between the wound dressing and the negative pressure source, and the liquid storage device is fluidly connected to the receiving space of the wound dressing housing and the negative pressure source through the negative pressure delivery conduit.

In another embodiment of the wound treatment system, the light emitting device has a first wavelength band of light ranging from 350 nm to 500 nm and a second wavelength band of light ranging from 600 nm to 850 nm.

In another embodiment of the wound treatment system, the light emitting device can emit a third wavelength band of light having a wavelength between 500 nm and 600 nm.

In another embodiment of the wound treatment system, the light emitting device emits the first wavelength band light, the second wavelength band light and the third wavelength band light in a sequential manner or a mixed manner.

In another embodiment of the wound treatment system, the light emitting device is an array of point light sources.

In another embodiment of the wound treatment system, the light emitting device is driven in a constant voltage or constant current manner.

In another embodiment of the wound treatment system, the image recognition module comprises: a receiving unit for receiving the light emitted by the light-emitting device to form a real-time image of the wound; and an output unit for transmitting the wound real-time image to the control module.

In another embodiment, the wound treatment system, the control module comprises: a driving unit for driving the negative pressure source, the light emitting device and the image identification module; a storage unit for storing a database containing a plurality of wound image data; and the operation unit is used for receiving the wound real-time image, comparing the wound real-time image with the wound image data in the database of the storage unit, then calculating and judging the wound stage and outputting a signal to the driving unit.

Drawings

FIG. 1: is a schematic view of a known wound dressing for use in a negative pressure therapy system;

FIG. 2: is a schematic illustration of an embodiment of a wound treatment system of the present invention;

FIG. 3A: is a schematic view of an embodiment of a wound dressing for a wound treatment system of the present invention;

FIG. 3B: is a schematic view of another embodiment of a wound dressing that is a wound treatment system of the present invention;

FIG. 4: is a schematic view of another embodiment of a wound treatment system of the present invention;

FIG. 5: is a schematic view of an embodiment of the light emitting device in the wound treatment system of the present invention;

FIG. 6: is a schematic view of another embodiment of a wound treatment system of the present invention;

FIG. 7: is a flow chart of an embodiment of a wound treatment system according to the present invention.

[ description of symbols ]

1. 2: wound dressing

11. 31: catheter tube

12. 22: wound contact layer

13. 26: absorbing layer

14: water-resistant layer

15. 25: wound healing device

2 a: opening of the container

2 b: accommodation space

21: shell body

23: barrier layer

23 a: tubular passage

3: negative pressure source

31 negative pressure conveying conduit

32: water-blocking breathable layer

33: liquid storage device

4: light emitting device

5: image identification module

51: receiving unit

52: output unit

6: control module

61: drive unit

62: storage unit

63: arithmetic unit

S1, S2, S3, S4, S41, S5, S51, S6: step (ii) of

Detailed Description

In order to make the features, contents and advantages of the present invention and the effects achieved thereby easier to understand, the present invention will be described in detail with reference to the accompanying drawings in the form of embodiments, and the drawings used therein are only for illustration and assistance of the description, and are not necessarily the actual proportion and the precise configuration after the implementation of the present invention, and therefore, the attached drawings should not be interpreted according to the proportion and the configuration relationship, and the scope of the right of the actual implementation of the present invention should not be defined.

Embodiments of a wound treatment system according to the present invention will be described below with reference to the accompanying drawings, and for ease of understanding, like elements in the embodiments described below are identified by like reference numerals.

Referring to fig. 2 and 3A together, in one embodiment, the wound treatment system includes: a wound dressing 2, comprising a housing 21 having an opening 2a, a wound contact layer 22 disposed on the opening 2a to cover a wound 25, and a barrier layer 23 separating the interior of the housing 21 from the wound contact layer 22 at the opening 2a to form a receiving space 2 b; wherein the barrier layer 23 comprises at least one tubular channel 23a, one orifice of the tubular channel 23a is located at the receiving space 2b side, and the other orifice of the tubular channel 23a is located at the wound contact layer 22 side; a negative pressure source 3, comprising a negative pressure delivery conduit 31 fluidly connected to the receiving space 2b of the wound dressing housing 21, for applying a negative pressure to the wound 25 via the negative pressure delivery conduit 31, such that tissue fluid exuded from the wound 25 can permeate through the wound contact layer 22 and reach the receiving space 2b via the tubular passage 23 a; a light emitting device 4, disposed in the receiving space 2b of the wound dressing 2, optically coupled to the barrier layer 23, and capable of emitting a first band light and a second band light; an image recognition module 5, the image recognition module 5 is disposed on one side of the opening 2a of the wound dressing shell 21 to receive the image light reflected by the wound 25 irradiated by the light emitted from the light emitting device 4; and a control module 6, wherein the control module 6 is electrically connected to the negative pressure source 3, the light-emitting device 4 and the image recognition module 5.

Referring to fig. 3B, in another embodiment of the wound treatment system, the receiving space 2B of the wound dressing 2 comprises an absorbent layer 26, for example, a material such as a polymer fiber, a fiber sponge, a foam material, a super absorbent polymer, a hydrogel material or a gel material, etc. is filled in the receiving space 2b to serve as an absorbing layer 26 for absorbing and storing tissue fluid, and the negative pressure delivery conduit 31 further has a water-blocking and air-permeable layer 32, for example, the water vapor transmission membrane or the polymer microporous membrane is made of polyethylene, polypropylene, polyvinyl alcohol, polyvinyl acetate, polytetrafluoroethylene, polyvinylidene fluoride, polyvinyl pyrrolidone, polyurethane, polyamide, polyester, polyacrylate, polymethacrylate, or polyacrylamide, etc. to prevent tissue fluid from entering the negative pressure source 3 through negative pressure suction to cause damage and pollution.

Referring to fig. 4, in another embodiment of the wound treatment system, a liquid storage device 33 is further included between the wound dressing 2 and the negative pressure source 3, and is respectively in fluid connection with the receiving space 2b of the wound dressing housing 21 and the negative pressure source 3 through the negative pressure delivery conduit 31, so as to absorb excessive and large amount of tissue exudate according to the condition of the wound 25, and further avoid increasing infection probability due to bacteria growing or uneven distribution of negative pressure or poor transmission efficiency due to blockage when the tissue exudate is adsorbed and stored near the wound 25.

The material of the barrier layer 23 includes, but is not limited to, water-blocking materials such as polyolefin, polyvinyl acetate, polyvinyl pyrrolidone, polyurethane, polyamide, polyester, polyacrylate, polymethacrylate, or polycarbonate. And a transparent material without coloring is preferably used in order to optically couple with the light-emitting device 4 without affecting transmittance and color shift. In order to avoid excessively stimulating the wound 25 and to enable the tissue fluid to smoothly enter the receiving space 2b through the tubular channel 23a of the blocking layer 23, the wound contact layer 22 generally employs soft polymer fibers, silica gel, hydrogel and other materials with solid holes, so that the refractive index of the materials is properly adjusted to match the refractive index of the blocking layer 23, so that the light rays in different wave bands emitted by the light emitting device 4 optically coupled to the blocking layer 23 can be better transmitted to the wound 25 as phototherapy light rays for assisting healing, and the image recognition module 5 disposed at one side of the opening 2a of the wound dressing shell 21 can receive the image light rays emitted by the light emitting device 4 and irradiated on the wound 25, so as to form a wound real-time image for determining the condition of the wound 25.

In another embodiment of the wound treatment system, the light emitting device 4 has a first wavelength band from red light to near-infrared light in a range from 350 nm to 500 nm, and a second wavelength band from blue light in a range from 600 nm to 850 nm. It is known that the red to near infrared wavelength band has a stimulating effect on fibroblasts which play an important role in wound 25 healing and can increase the proliferation efficiency. The blue light band is known to reduce the average survival rate of bacteria such as pseudomonas aeruginosa, which are commonly present in wounds 25 and cause inflammation.

In another embodiment of the wound treatment system, the light emitting device 4 further emits a third wavelength band of light, and the wavelength of the third wavelength band of light is a green wavelength band between 500 nm and 600 nm. Although the green light does not assist the healing of the wound 25, the full visible light band can be formed by matching the green light band with the existing red and blue light bands, so that the image recognition module 5 can better form a real-time image of the wound to provide a control module for comparison, for example, by comparing different colors of the wound 25, such as bright red granulation tissue with good oxygen congestion degree, inflamed and dead yellow and white cell tissue, and necrotic black eschar, with the ratio of each area in the wound 25, the healing stage of the wound 25 can be more accurately judged. The light emitting device 4 can emit the first, second and third wavelength light beams in a sequential manner to obtain the non-interference instant images of the single optical wounds and then recombine the images into full-visible spectrum images, or can directly and rapidly obtain full-color instant images of the wounds in a mixed light manner.

Referring to fig. 5, in another embodiment of the wound treatment system, the light emitting device 4 is a point light source array, which may be a plurality of single light lasers, light emitting diodes or organic light emitting diodes packaged and blocked from water and oxygen penetration. Therefore, the blocking layer 23 can be easily arranged in a staggered way without affecting the negative pressure treatment effect. And because these excitation light sources are not single Full visible light wave band light sources, can more easily obtain the pure color light source with narrower Full width at half maximum (FWHM), and can design the point light source array arrangement combination mode with better identification rate according to the wound images with different areas and depths, so as to be received and recombined by the image identification module 5 into the high-resolution wound instant image.

In another embodiment of the wound treatment system, the light emitting device 4 may form a light source with stable light intensity by using a local dimming technology mature in the field of liquid crystal display backlight driving, so as to perform phototherapy or form instant images of the wound. However, the irradiance of the light-emitting device 4 in the phototherapy period is preferably between 5mW/cm ² To 25mW/cm ² And the irradiation energy density is between 1J/cm ² To 5J/cm ² To provide adequate therapeutic strength and avoid excessive irritation of the wound tissue without the outer skin protection.

Referring to fig. 6, in another embodiment of the wound treatment system, the image recognition module 5 includes: a receiving unit 51 for receiving the light emitted from the light emitting device 4 to form a real-time image of the wound; and an output unit 52 for transmitting the real-time wound image to the control module 6.

In another embodiment of the wound treatment system, the control module 6 includes: a driving unit 61 for driving the negative pressure source 3, the light emitting device 4 and the image recognition module 5; a storage unit 62 for storing a database containing a plurality of wound image data; and an operation unit 63 for receiving the wound real-time image from the image recognition module 5, comparing the wound image data in the database of the storage unit 62, and then calculating and determining the wound stage and outputting a signal to the driving unit 61.

Referring to fig. 6 and 7 together, fig. 7 is a flow chart illustrating an embodiment of a wound treatment system according to the present invention.

In step S1, the driving unit 61 of the control module 6 drives the light emitting device 4 to emit light beams of different wavelength bands, such as light beams of a first wavelength band and light beams of a second wavelength band, so as to provide the light source for the image recognition module 5.

In step S2, the driving unit 61 of the control module 6 drives the image recognition module 5, the receiving unit 51 receives the light source emitted by the light emitting device 4 and forms an instant image of the wound, and the instant image of the wound is transmitted to the control module 6 through the output unit 52.

In step S3, the control module 6 compares the instant wound image with the data of the wound images in the database of the storage unit 62 through the operation unit 63, determines whether the healing stage of the current wound belongs to the inflammatory stage, the proliferative stage or the healed stage, and outputs a corresponding signal to the driving unit 61.

In step S4, when the operation unit 63 determines that the instant image feature of the wound matches the inflammatory-phase wound feature in the wound image data in the database, the driving unit 61 drives the light emitting device 4 to emit the first band light of blue light for bacteriostasis, and drives the negative pressure source 3 to provide a first pressure to the wound dressing 2.

In step S41, the light and negative pressure values in step S4 are maintained and maintained until the end of a predetermined first treatment period corresponding to the inflammatory phase, and step S1 is repeated again to determine whether the wound is improved after the first treatment period or needs to be performed again for a second first treatment period.

In step S5, when the operation unit 63 determines that the real-time image features of the wound conform to the proliferation-stage wound features in the image data of the wound in the database of the storage unit 62, the driving unit 61 drives the light-emitting device 4 to emit light of the second wavelength band from red light to near-infrared light to assist fibroblast proliferation, and drives the negative pressure source 3 to provide a second pressure to the wound dressing 2. Since pus is generally produced during the hyperplastic phase rather than inflammatory, the second pressure may generally be less than the first pressure required during the inflammatory phase to minimize wound discomfort in the patient.

In step S51, the light and negative pressure values in step S5 are maintained and maintained until a predetermined second treatment period conforming to the proliferative phase is completed, and step S1 is repeated again to determine whether the wound is improved or infected after the second treatment period or needs to be performed again for a second treatment period.

In step S6, when the operation unit 63 determines that the instant image feature healing degree of the wound already matches the healing wound features in the image data of the wound in the database of the storage unit 62, the whole treatment procedure of the wound treatment system is ended.

The above-described embodiments are merely illustrative of the technical spirit and features of the present invention, and the object of the present invention is to enable those skilled in the art to understand the content of the present invention and to implement the same, while the scope of the claims of the present invention is not limited thereto, i.e. all equivalent changes and modifications made in the spirit of the present invention should be covered by the claims of the present invention.

Claims

1. A wound treatment system, comprising:

the wound dressing comprises a shell with an opening, a wound contact layer arranged on the opening to cover a wound, and a barrier layer for separating the interior of the shell and the wound contact layer at the opening to form a containing space; wherein, the barrier layer comprises at least one tubular channel, one orifice of the tubular channel is positioned at the side of the containing space, and the other orifice of the tubular channel is positioned at the side of the wound contact layer; a negative pressure source comprising a negative pressure delivery conduit in fluid communication with the receiving space of the wound dressing housing for applying a negative pressure to the wound via the negative pressure delivery conduit such that interstitial fluid exuded from the wound can permeate the wound contact layer and pass through the tubular passage to the receiving space;

a light emitting device disposed in the receiving space of the wound dressing, optically coupled to the barrier layer, and capable of emitting a first band light and a second band light;

the image identification module is arranged on one side of the opening of the wound dressing shell and used for receiving the image light rays reflected by the wound irradiated by the light rays emitted by the light-emitting device; and

and the control module is electrically connected with the negative pressure source, the light-emitting device and the image identification module.

2. The wound treatment system of claim 1, wherein the receiving space of the wound dressing comprises an absorbent layer, and the negative pressure delivery conduit further comprises a water-blocking gas-permeable layer to prevent tissue fluid from entering the negative pressure source.

3. The wound treatment system of claim 1, further comprising a reservoir between the wound dressing and the negative pressure source, and fluidly connected to the receiving space of the wound dressing housing and the negative pressure source via the negative pressure delivery conduit, respectively.

4. The wound treatment system of claim 1, wherein the light emitting device has a first wavelength range of 350 nm to 500 nm and a second wavelength range of 600 nm to 850 nm.

5. The system of claim 4, wherein the light emitting device emits a third wavelength band of light having a wavelength between 500 nm and 600 nm.

6. The system of claim 5, wherein the light emitting device emits the first, second and third bands of light in a sequential or mixed manner.

7. The wound treatment system of claim 1, wherein the light emitting device is an array of point light sources.

8. The wound treatment system of claim 1, wherein the light emitting device is driven in a constant voltage or constant current manner.

9. The wound treatment system of claim 1, wherein the image recognition module comprises:

a receiving unit for receiving the light emitted by the light-emitting device to form a real-time image of the wound; and

and the output unit is used for transmitting the wound real-time image to the control module.

10. The wound treatment system of claim 9, wherein the control module comprises:

a driving unit for driving the negative pressure source, the light emitting device and the image identification module;

a storage unit for storing a database containing a plurality of wound image data; and

and the operation unit is used for receiving the wound real-time image from the image identification module, comparing the wound real-time image with the plurality of wound image data in the database of the storage unit, judging the wound stage through operation and outputting a signal to the driving unit.