CN114854266B - Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates - Google Patents
Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates Download PDFInfo
- Publication number
- CN114854266B CN114854266B CN202210288157.3A CN202210288157A CN114854266B CN 114854266 B CN114854266 B CN 114854266B CN 202210288157 A CN202210288157 A CN 202210288157A CN 114854266 B CN114854266 B CN 114854266B
- Authority
- CN
- China
- Prior art keywords
- parts
- agent
- heat
- antioxidant
- epoxy resin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D151/00—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
- C09D151/06—Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to homopolymers or copolymers of aliphatic hydrocarbons containing only one carbon-to-carbon double bond
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/20—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for coatings strippable as coherent films, e.g. temporary coatings strippable as coherent films
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/60—Additives non-macromolecular
- C09D7/61—Additives non-macromolecular inorganic
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/60—Additives non-macromolecular
- C09D7/63—Additives non-macromolecular organic
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/65—Additives macromolecular
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2237—Oxides; Hydroxides of metals of titanium
- C08K2003/2241—Titanium dioxide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/08—Stabilised against heat, light or radiation or oxydation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Adhesives Or Adhesive Processes (AREA)
Abstract
The invention discloses a breathable easy-to-tear heat-seal adhesive capable of being heat-sealed on various substrates, which comprises the following components in parts by weight: 15-30 parts of acrylate copolymer, 12-35 parts of maleic anhydride grafted polyethylene resin, 8-19 parts of modified epoxy resin, 5-10 parts of 1, 6-hexamethylene diisocyanate, 1-6 parts of dodecyl fatty acid polyoxyethylene ether, 4-8 parts of polybutylene, 0.5-1.5 parts of a solidifying agent, 50-85 parts of a solvent, 0.1-0.3 part of an ultraviolet eliminator, 0.5-1.2 parts of a blending agent, 0.1-0.5 part of a smoothing agent, 0.1-0.2 part of an antioxidant, 0.5-4 parts of an excipient and 0.2-0.6 part of a defoaming agent. The invention has good thermal creep resistance, aging resistance, high peel strength, good air permeability and excellent comprehensive performance in all aspects.
Description
Technical Field
The invention relates to the field of sterilization and packaging of medicines and medical instruments, in particular to an easy-to-tear heat-sealing adhesive which is breathable and can be thermally sealed on various base materials.
Background
Among various medical or pharmaceutical packaged products, the sterilized products need to be sterilized by ethylene oxide, steam or radiation, wherein the ethylene oxide is used in a relatively large amount in a sterilization mode, and the required sterilized packages are relatively large. Conventional medical packaging using ethylene oxide sterilization requires the following: 1. it is necessary to adapt to ethylene oxide sterilization conditions. Due to the fact that negative pressure pumping is involved in sterilization to cause bag expansion, under certain temperature and humidity conditions, the hot creep is challenging. 2. Aging resistance, ensuring that the sterilized product can endure 3-10 years of shelf life. 3. The air permeability is good, and the ethylene oxide sterilizing gas can completely pass through. Therefore, the heat-sealing glue for packaging the medical equipment is designed, can adapt to the ethylene oxide sterilization condition, and still keeps the performance after multiple times of sterilization, which is a technical problem to be solved urgently by the technical personnel in the field.
Disclosure of Invention
The invention provides the easy-to-tear heat-sealing adhesive which is breathable and can be thermally sealed on various substrates, and has the advantages of good thermal creep resistance, aging resistance, high peel strength, good air permeability and excellent comprehensive performance in all aspects.
In order to achieve the purpose, the technical scheme of the invention is to provide an easy-to-tear heat-seal adhesive which is breathable and can be thermally sealed on various substrates, wherein the heat-seal adhesive comprises the following components in parts by weight: 15-30 parts of acrylate copolymer, 12-35 parts of maleic anhydride grafted polyethylene resin, 8-19 parts of modified epoxy resin, 5-10 parts of 1, 6-hexamethylene diisocyanate, 1-6 parts of dodecyl fatty acid polyoxyethylene ether, 4-8 parts of polybutylene, 0.5-1.5 parts of a solidifying agent, 50-85 parts of a solvent, 0.1-0.3 part of an ultraviolet eliminator, 0.5-1.2 parts of a blending agent, 0.1-0.5 part of a smoothing agent, 0.1-0.2 part of an antioxidant, 0.5-4 parts of an excipient and 0.2-0.6 part of a defoaming agent.
The modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70-80 ℃, and the solid content is 35-45%. The Tg point of the resin refers to the glass transition temperature of the resin, i.e., the temperature at which the polymer changes from a high elastic state to a glassy state. The heat-seal gluing can have excellent creep resistance by selecting proper resin materials, and the peel strength of the heat-seal gluing is improved. The p-hydroxybenzoic acid also has the bactericidal effect, so that the heat-seal glue has certain bactericidal and bacteriostatic capacities.
The solidifying agent is one or more of dimethylaminopropylamine, m-phenylenediamine and diaminodiphenylmethane. The solidifying agent is a substance for promoting or controlling the solidifying, forming, heat sealing and gluing reaction. The resin curing is performed by chemical reactions such as condensation, closed loop, addition or catalysis, so that the resin has an irreversible change process, the thermal creep resistance of the material is improved, the peel strength of the heat-seal gluing is improved, and the curing is realized by adding a solidifying agent.
Further, the solvent is one or more of isopropyl acetate, butanone and isopropanol. Three solvents with good solubility and low boiling point are selected to have low toxicity to human bodies. The solvent recovery system can be used for recovering and reusing the low-toxicity solvent.
Further, the ultraviolet eliminating agent is one or more of nano titanium dioxide, 2-hydroxy-4-methoxy benzophenone and hexamethyl phosphoric triamide. The ultraviolet eliminator is a light stabilizer, can absorb ultraviolet rays, reduces damage of the ultraviolet rays to materials, and improves aging resistance of heat-seal gluing, so that weather resistance of the materials is enhanced.
The blending agent is one or more of 2-methylpropanesulfonic acid, hydroxypropyl acrylate and sodium propylene sulfonate. The blending agent is a substance with two functional groups with different properties, and the molecular structure of the blending agent is mainly characterized in that the molecule contains two groups with different chemical properties, one group is an inorganophilic group and is easy to chemically react with the surface of an inorganic substance; the other is an organophilic group which can react with synthetic resin or other polymers or generate hydrogen bonds to be dissolved in the easily-torn heat-sealing glue, thereby improving the peeling strength of the glue material.
The smoothing agent is one or more of polymeric urea, polyethylene wax and polyamide wax. The smoothing agent forms a strong network structure in a heat-seal gluing solution, has excellent thixotropic property, excellent sagging prevention capability and sedimentation prevention capability, can keep the storage stability of heat-seal gluing slurry, prevents the slurry from layering and other problems, thereby increasing the uniformity of components of the glue material, promoting the realization of air permeability, and simultaneously being assisted with the selection of different gluing layer thicknesses, realizing the selection of more air permeability.
The excipient is one or more of diisononyl phthalate, zinc ethyl phenyl dithiocarbamate and didecyl phthalate. The excipient is a macromolecular auxiliary agent, has high boiling point, is difficult to volatilize, and has good miscibility with the polymers of all the components. The excipient is distributed among macromolecular chains, so that intermolecular force is reduced, the viscosity of the polymer is reduced, the processability is improved, the thermal creep resistance of the material is improved, and the peel strength of heat-sealing gluing is increased.
The antioxidant is one or more of antioxidant 168, antioxidant 1076 and antioxidant 164. The material is heated and sheared to generate free radicals, and the free radicals generate peroxide free radicals when meeting oxygen, and the peroxide free radicals further deprive hydrogen atoms from the main chain of the polymer to generate relatively stable polymer-based hydroperoxide. The cycle is repeated, the chain grows, and the reaction is gradually enlarged. The hydrogen donor antioxidant is mainly used for preventing or delaying aging and deterioration of the heat-seal gluing material, and simultaneously has other components of a stabilizing system, so that the antioxidant can fully play a synergistic effect and has effects on maintaining the peel strength performance and stabilizing the strength performance of the heat-seal gluing material.
The defoaming agent is one or more of simethicone, cyanuric chloride melamine and polyoxypropylene glycerol ether. Defoaming agents are substances that lower the surface tension of water, solutions, suspensions, etc., prevent foam formation, or reduce or eliminate the original foam. The use of the defoaming agent can ensure that the heat-seal gluing keeps the system character stable, increase the weather resistance of the material and increase the performances of the heat-seal gluing in all aspects.
The invention has the advantages and beneficial effects that: the sizing can be performed on a variety of substrates such as dialysis paper, tyvek, and the like. The aseptic package has white color transfer when opened, is suitable for epoxy sterilization conditions, has good thermal creep resistance, and has creep rate less than 10 percent after 5 times of sterilization. The adhesive has good aging resistance, and the performance of the adhesive does not change after aging for more than 5 years. The peeling strength of various base materials is high, and the peeling strength is 4-8N/15mm under the condition of meeting the requirement of easy peeling. The permeability is good, the permeability value is increased on the substrate by only 10-50s GurleySeconds, and the ethylene oxide sterilization gas can completely pass through. The invention has obvious cost advantage, excellent comprehensive performance in all aspects, strong industrialization capability, stable and controllable quality and stronger application prospect.
Detailed Description
The following examples are provided to further illustrate embodiments of the present invention. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.
Example 1
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 15 parts of acrylate copolymer, 12 parts of maleic anhydride grafted polyethylene resin and 8 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70 ℃, the solid content is 35%, 5 parts of 1, 6-hexamethylene diisocyanate, 1 part of dodecyl fatty acid polyoxyethylene ether, 4 parts of polybutene, 0.5 part of dimethylaminopropylamine solidifying agent, 50 parts of isopropyl acetate solvent, 0.1 part of nano titanium dioxide ultraviolet remover, 0.5 part of 2-methylpropanesulfonic acid blending agent, 0.1 part of polymeric urea smoothing agent, 0.1 part of antioxidant 168, 0.5 part of diisononyl phthalate excipient and 0.2 part of simethicone defoaming agent.
Example 2
The easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates is characterized by comprising the following components in percentage by weight: the heat-seal adhesive comprises the following components in parts by weight: 30 parts of acrylate copolymer, 35 parts of maleic anhydride grafted polyethylene resin and 19 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 80 ℃, the solid content is 45%, 10 parts of 1, 6-hexamethylene diisocyanate, 6 parts of dodecyl fatty acid polyoxyethylene ether, 8 parts of polybutene, 1.5 parts of m-phenylenediamine consolidation agent, 85 parts of butanone solvent, 0.3 part of 2-hydroxy-4-methoxybenzophenone ultraviolet remover, 1.2 parts of hydroxypropyl acrylate blending agent, 0.5 part of polyethylene wax smoothing agent, 0.2 part of antioxidant 1076, 4 parts of zinc ethyl phenyl dithiocarbamate excipient and 0.6 part of cyanuric chloride melamine defoamer.
Example 3
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 30 parts of acrylate copolymer, 12 parts of maleic anhydride grafted polyethylene resin and 19 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70 ℃, the solid content is 45%, 5 parts of 1, 6-hexamethylene diisocyanate, 6 parts of dodecyl fatty acid polyoxyethylene ether, 4 parts of polybutylene, 1.5 parts of diaminodiphenylmethane solidifying agent, 50 parts of isopropanol solvent, 0.3 part of hexamethyl phosphoric triamide ultraviolet remover, 0.5 part of sodium propylene sulfonate blending agent, 0.5 part of polyamide wax smoothing agent, 0.1 part of antioxidant 164, 4 parts of didecyl phthalate excipient and 0.2 part of polyoxypropylene glycerol ether defoaming agent.
Example 4
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 15 parts of acrylate copolymer, 35 parts of maleic anhydride grafted polyethylene resin and 8 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 80 ℃, the solid content is 35%, 10 parts of 1, 6-hexamethylene diisocyanate, 1 part of dodecyl fatty acid polyoxyethylene ether, 8 parts of polybutene and the weight percent of dimethylaminopropylamine: 0.5 part of a solidifying agent with m-phenylenediamine wt% =1, 85 parts of a butanone solvent, 0.1 part of a 2-hydroxy-4-methoxybenzophenone ultraviolet eliminating agent, 1.2 parts of a hydroxypropyl acrylate blending agent, 0.1 part of a polyethylene wax smoothing agent, 0.2 part of an antioxidant 168, 0.5 part of a diisononyl phthalate excipient and 0.6 part of a cyanuric chloride melamine defoamer.
Example 5
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 20 parts of acrylate copolymer, 20 parts of maleic anhydride grafted polyethylene resin and 10 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 75 ℃, the solid content is 35%, 8 parts of 1, 6-hexamethylene diisocyanate, 3 parts of dodecyl fatty acid polyoxyethylene ether, 6 parts of polybutene, 1 part of diaminodiphenylmethane solidifying agent and the weight percent of butanone: 60 parts of isopropanol wt% =1 solvent, 0.2 parts of titanium dioxide ultraviolet eliminator, 0.8 part of hydroxypropyl acrylate blending agent, 0.3 part of polymeric urea smoothing agent, 0.1 part of antioxidant 164, 2 parts of didecyl phthalate excipient and 0.4 part of polyoxypropylene glycerol ether defoamer.
Example 6
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 25 parts of acrylate copolymer, 30 parts of maleic anhydride grafted polyethylene resin and 15 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 80 ℃, the solid content is 40%, 10 parts of 1, 6-hexamethylene diisocyanate, 5 parts of dodecyl fatty acid polyoxyethylene ether, 7 parts of polybutene, 1.5 parts of dimethylaminopropylamine consolidating agent, 75 parts of isopropanol solvent and 15 parts of hexamethyl phosphoric triamide by weight percent: 0.1 part of nano titanium dioxide wt% =1: 0.8 part of a blending agent of sodium propylene sulfonate wt% = 1.
Example 7
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 15 parts of acrylate copolymer, 15 parts of maleic anhydride grafted polyethylene resin and 12 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70 ℃, the solid content is 35%, 6 parts of 1, 6-hexamethylene diisocyanate, 4 parts of dodecyl fatty acid polyoxyethylene ether, 6 parts of polybutene, 0.5 part of dimethylaminopropylamine solidifying agent, 50 parts of isopropyl acetate solvent, 0.1 part of 2-hydroxy-4-methoxybenzophenone ultraviolet remover, 0.5 part of 2-methylpropanesulfonic acid blending agent and polyethylene wax wt%: 0.2 part of a smoothing agent with the weight percent of polyamide wax being not less than 1, and 1076 parts of an antioxidant: antioxidant 164=3, 1.5 parts of diisononyl phthalate excipient, and 0.3 parts of polyoxypropylene glycerol ether defoamer.
Example 8
The easy-to-tear heat-sealing adhesive is breathable and can be thermally sealed on various substrates, and is characterized in that: the heat-seal adhesive comprises the following components in parts by weight: 30 parts of acrylate copolymer, 32 parts of maleic anhydride grafted polyethylene resin and 11 parts of modified epoxy resin, wherein the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70 ℃, the solid content is 35%, 8 parts of 1, 6-hexamethylene diisocyanate, 4 parts of dodecyl fatty acid polyoxyethylene ether, 7 parts of polybutylene, 1 part of m-phenylenediamine consolidation agent, 55 parts of isopropanol solvent, 0.2 part of hexamethyl phosphoric triamide ultraviolet remover, 0.9 part of hydroxypropyl acrylate blending agent, 0.4 part of polymeric urea smoothing agent, 0.1 part of antioxidant 164, and wt% of diisononyl phthalate: 3.5 parts of excipient of zinc ethyl phenyl dithiocarbamate wt% =1, cyanuric chloride melamine wt%: 0.5 part of a defoaming agent with the weight percent of polyoxypropylene glycerol ether being = 1.
Comparative example
The comparative example is based on example 1 with the difference that no modified epoxy resin was added in comparative example 1, no consolidating agent was added in comparative example 2, no blending agent was added in comparative example 3, and no smoothing agent was added in comparative example 4.
Examples 1-8 and comparative examples comparative tests on the performance of the easy release heat seal adhesive, examples 1-4, comparative examples 1-4, tyvek was used as the adhesive substrate, and examples 5-8 used dialysis paper as the adhesive substrate.
1. Inventive and comparative example test results for examples 1-8
By considering examples 1-8, the creep rate was less than 10% after 5 times of sterilization at a sterilization temperature of 40-60 ℃ and a humidity of 40-90%. The comparative example 2 has no consolidation agent, the creep rate of the coating adhesive is increased most, and the comparative example 1 has no modified epoxy resin, so that the creep rate is greatly increased, so that the thermal creep resistance of the material can be obviously changed by adding the modified epoxy resin and the curing agent in the heat-sealing coating adhesive, and meanwhile, the creep rate can be influenced to a certain extent by adding the blending agent. In the aspect of the increase of the air permeability, the air permeability of the comparative example 1, the comparative example 2 and the comparative example 3 is stable and is not obviously changed. Comparative example 4, in which no smoothing agent was added, had a significantly increased air permeability value and deteriorated air permeability, indicating that the addition of the smoothing agent can change the air permeability of the heat seal adhesive. The peeling strength of the invention is 4-8N/15mm, the peeling strength is high, the requirement of easy uncovering is satisfied, the peeling strength of comparative example 1, comparative example 2 and comparative example 3 is reduced in different degrees, the minimum is only 3N/15mm, the material modification of the heat-seal gluing can be seen, and the peeling strength of the heat-seal gluing can be greatly improved by using the modified epoxy resin, the consolidation agent, the blending agent and the like.
The invention can be used for gluing on various base materials such as dialyzing paper, tyvek and the like. The aseptic package has white color transfer when opened, is suitable for epoxy sterilization conditions, has good thermal creep resistance, and has creep rate less than 10 percent after 5 times of sterilization. The adhesive has good aging resistance, and the performance of the adhesive does not change after aging for more than 5 years through testing. On various base materials, the peel strength is high, and under the condition of meeting the requirement of easy uncovering, the peel strength is 4-8N/15mm. The permeability is good, the permeability value is increased on the substrate by only 10-50s GurleySeconds, and the ethylene oxide sterilization gas can completely pass through. The invention has obvious cost advantage, excellent comprehensive performance in all aspects, strong industrialization capability, stable and controllable quality and stronger application prospect.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the technical principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.
Claims (5)
1. The easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates is characterized by comprising the following components in percentage by weight: the heat-seal glue comprises the following components in parts by weight: 15-30 parts of acrylate copolymer, 12-35 parts of maleic anhydride grafted polyethylene resin, 8-19 parts of modified epoxy resin, 5-10 parts of 1, 6-hexamethylene diisocyanate, 1-6 parts of dodecyl fatty acid polyoxyethylene ether, 4-8 parts of polybutylene, 0.5-1.5 parts of a solidifying agent, 50-85 parts of a solvent, 0.1-0.3 part of an ultraviolet eliminator, 0.5-1.2 parts of a blending agent, 0.1-0.5 part of a smoothing agent, 0.1-0.2 part of an antioxidant, 0.5-4 parts of an excipient and 0.2-0.6 part of a defoaming agent; the modified epoxy resin is p-hydroxybenzoic acid epoxy resin, the Tg point is 70-80 ℃, and the solid content is 35-45%; the solidifying agent is one or more of dimethylaminopropylamine, m-phenylenediamine and diaminodiphenylmethane; the blending agent is one or more of 2-methyl propanesulfonic acid, hydroxypropyl acrylate and sodium propylene sulfonate; the smoothing agent is one or more of polymeric urea, polyethylene wax and polyamide wax; the excipient is one or more of diisononyl phthalate, zinc ethyl phenyl dithiocarbamate and didecyl phthalate.
2. The easy release heat seal adhesive of claim 1, which is breathable and sealable to a variety of substrates, wherein: the solvent is one or more of isopropyl acetate, butanone and isopropanol.
3. A breathable, easy release, heat sealable adhesive which is heat sealable to a variety of substrates according to claim 2 wherein: the ultraviolet eliminating agent is one or more of nano titanium dioxide, 2-hydroxy-4-methoxy benzophenone and hexamethylphosphoric triamide.
4. The easy release heat seal adhesive of claim 1, which is breathable and sealable to a variety of substrates, wherein: the antioxidant is one or more of antioxidant 168, antioxidant 1076 and antioxidant 164.
5. The easy release heat seal adhesive of claim 1, which is breathable and sealable to a variety of substrates, wherein: the defoaming agent is one or more of simethicone, cyanuric chloride melamine and polyoxypropylene glycerol ether.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210288157.3A CN114854266B (en) | 2022-03-23 | 2022-03-23 | Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210288157.3A CN114854266B (en) | 2022-03-23 | 2022-03-23 | Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114854266A CN114854266A (en) | 2022-08-05 |
| CN114854266B true CN114854266B (en) | 2023-02-10 |
Family
ID=82627824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210288157.3A Active CN114854266B (en) | 2022-03-23 | 2022-03-23 | Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114854266B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108251016A (en) * | 2018-01-30 | 2018-07-06 | 上海汉熵新材料科技有限公司 | Based on two-component universal medical device package water base heat-seal adhesive and preparation method thereof |
| CN108264874A (en) * | 2017-12-29 | 2018-07-10 | 上海乘鹰新材料有限公司 | For drug blister package high speed medicine-packaging machine high temperature heat-resistant sealing and preparation method thereof |
| CN108587521A (en) * | 2018-04-20 | 2018-09-28 | 无锡市健鼎包装技术有限公司 | A kind of medical dialyzing paper aqueous coating heat-seal adhesive and its coating process |
| CN110589230A (en) * | 2019-09-04 | 2019-12-20 | 湖州金洁实业有限公司 | High-temperature-resistant aluminum foil easy to tear and cover |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63295627A (en) * | 1987-05-27 | 1988-12-02 | Matsushita Electric Ind Co Ltd | Outer packaging rim material and molding thereof |
-
2022
- 2022-03-23 CN CN202210288157.3A patent/CN114854266B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108264874A (en) * | 2017-12-29 | 2018-07-10 | 上海乘鹰新材料有限公司 | For drug blister package high speed medicine-packaging machine high temperature heat-resistant sealing and preparation method thereof |
| CN108251016A (en) * | 2018-01-30 | 2018-07-06 | 上海汉熵新材料科技有限公司 | Based on two-component universal medical device package water base heat-seal adhesive and preparation method thereof |
| CN108587521A (en) * | 2018-04-20 | 2018-09-28 | 无锡市健鼎包装技术有限公司 | A kind of medical dialyzing paper aqueous coating heat-seal adhesive and its coating process |
| CN110589230A (en) * | 2019-09-04 | 2019-12-20 | 湖州金洁实业有限公司 | High-temperature-resistant aluminum foil easy to tear and cover |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114854266A (en) | 2022-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108587521B (en) | Water-based coating heat-sealing adhesive for medical dialyzing paper and coating process thereof | |
| AU2008354925B2 (en) | Thermosetting resin containing irradiated thermoplastic toughening agent | |
| CN101798403B (en) | Method for preparing chitosan/polyving alcohol/polylactic acid blended dense membrane | |
| CN110846931B (en) | Novel environment-friendly high-barrier direct plating paper and preparation process thereof | |
| CN114854266B (en) | Breathable easy-to-tear heat-sealing adhesive capable of being thermally sealed on various substrates | |
| CN108582904A (en) | A kind of uvioresistant Obstruct membrane and preparation method thereof | |
| CN108299711A (en) | A kind of anti-bacterial packaging film and processing method | |
| Gorrasi et al. | Controlled release mechanisms of sodium benzoate from a biodegradable polymer and halloysite nanotube composite | |
| Rutnakornpituk et al. | Surface and mechanical properties of microporous membranes of poly (ethylene glycol)–polydimethylsiloxane copolymer/chitosan | |
| CN108250475A (en) | A kind of PVDC coating materials with high obstructing performance and preparation method thereof | |
| CN101966430B (en) | Preparation method of high-efficient hydrophilic modified polypropylene hollow fibrous membrane | |
| CN108251016B (en) | Based on two-component universal medical device package water base heat-seal adhesive and preparation method thereof | |
| EP3652246B1 (en) | Sterilizable medical packaging with living pores | |
| CN106753176A (en) | A kind of aqueous polyurethane cardboard adhesive of Antimicrobial preservative excellent performance and preparation method thereof | |
| JP5309048B2 (en) | Composition for producing porous EVA coating film | |
| CN108395564A (en) | A kind of high-barrier PE coated films and preparation method thereof for liquid food packing | |
| KR101907419B1 (en) | Accelerator for epoxy resin and epoxy composition using the same | |
| CN104194016A (en) | Nanometer peanut protein macromolecular composite membrane and preparation method thereof | |
| CN108314794A (en) | A kind of high barrier coating material and preparation method thereof | |
| CN110283326A (en) | A kind of degradable modification poly (propylene carbonate) and preparation method thereof | |
| CN108559120A (en) | A kind of high-barrier PE coated films and preparation method thereof for liquid food packing | |
| CN108928559A (en) | A kind of preparation method of high tensile elasticity cellulose membrane | |
| Stiubianu et al. | Modification of water sorption capacity of polydimethylsiloxane based composites by incorporation of lignin | |
| CN114149581A (en) | Lignin-based hydrogen bond organic framework nano material and preparation method and application thereof | |
| CN117757388A (en) | EAA (ethylene-propylene-diene monomer) water-based heat-sealing adhesive for medical sterilization packaging and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |