CN114849807A - Multi-channel needle release device and needle release method - Google Patents
Multi-channel needle release device and needle release method Download PDFInfo
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- CN114849807A CN114849807A CN202210205337.0A CN202210205337A CN114849807A CN 114849807 A CN114849807 A CN 114849807A CN 202210205337 A CN202210205337 A CN 202210205337A CN 114849807 A CN114849807 A CN 114849807A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1037—Using surface tension, e.g. pins or wires
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/30—Nuclear fission reactors
Abstract
The invention discloses a multi-channel needle release device, which comprises a motor, a motor fixing plate, a connecting plate, a gun arranging cavity, a needle release plate, needle release rods, an adapter and a needle release sleeve, wherein the multi-channel needle release device drives the connecting plate to move downwards through the motor so as to extrude the needle release rods on two sides, so that the needle release plate is driven to move downwards, the lower side surface of the needle release plate is provided with steps with the same number as that of channels, the height from the step of the first channel to the step of the last channel is gradually reduced, multi-channel automatic needle release operation is realized, the problems of detection interruption and low efficiency caused by high abnormal needle release rate of multi-channel needle release operation in the prior art are solved, and the problems of equipment aging fault and high maintenance fault rate caused by excessive load of a driving module are solved. Compared with the prior art, the multi-channel automatic ladder-shaped needle removal operation can be realized, the needle removal abnormal rate is greatly reduced, the operation process is stable, and the working efficiency of nucleic acid extraction is greatly improved.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a multi-channel needle removing device and a needle removing method.
Background
The full-automatic nucleic acid extraction instrument is an instrument integrating functions of sample distribution, reagent distribution, liquid transfer, magnetic attraction, oscillation mixing and the like required by nucleic acid extraction and purification tests based on a magnetic bead separation principle methodology, generally uses a 96-hole deep-hole plate as a test carrier, and can realize automatic extraction and purification of high-flux and high-purity nucleic acid. The full-automatic nucleic acid extractor generally comprises a sample adding arm module, an oscillation module, a sample test tube rack module, a magnetic rack module and the like.
The full-automatic nucleic acid extractor generally adopts a disposable sample adding needle to absorb liquid and distribute the absorbed liquid to a reaction plate so as to avoid cross contamination, and therefore, a sample adding arm module needs to be provided with an automatic needle taking and automatic needle releasing module. In the prior art, a single cylinder is adopted to simultaneously remove needles from four channels of once sample adding needles in a reported manner, however, in the needle removing operation process, the removal of the once sample adding needles needs to overcome large frictional resistance, particularly when multiple channels are arranged, the frictional resistance is multiplied, the driving force cannot meet the requirement of multi-channel needle removing, the phenomenon that individual channels fail to remove needles easily occurs, the experimental efficiency is influenced, and when multiple channels are used for removing needles, the multi-channel needle removing device is limited by the moment of a single driving device, so that the driving module is overloaded, easy aging and failure occur, and the maintenance cost is increased.
Therefore, research and improvement on a multi-channel needle release device and a needle release method are needed to solve the problems in the prior art.
Disclosure of Invention
The invention provides a multi-channel needle removing device and a needle removing method in order to overcome the defects in the prior art. The multi-channel needle release device can realize multi-channel automatic ladder-shaped needle release operation, greatly reduce the abnormal rate of needle release, and has stable operation process, greatly improves the working efficiency of nucleic acid extraction, avoids aging faults caused by overweight loading of the driving module, and reduces the maintenance fault rate.
The invention provides a multi-channel needle removal device which comprises:
the utility model provides a needle device is taken off to multichannel, its characterized in that includes motor, motor fixed plate, connecting plate, row's rifle cavity, takes off the faller, takes off the needle bar, adapter and takes off the needle cover, the motor sets up in the upper portion that the needle device was taken off to the multichannel through the motor fixed plate, the output shaft of motor with the connecting plate is connected, row's rifle cavity pass through the linking frame with the motor fixed plate is connected, take off the upper end of needle bar and connect the connecting plate, take off the needle bar and pass row's rifle cavity, its lower extreme with it is connected to take off the faller, the adapter passes take off the faller with row's rifle cavity is connected, it locates to take off the needle cover the adapter with take off faller elastic connection, the downside that takes off the faller has the ladder the same with the channel number, first passageway ladder highly degressive in proper order to last passageway ladder.
Furthermore, the upper end of the needle releasing rod is sleeved with a spring, and the position of the spring is located between the connecting plate and the gun arranging cavity.
Furthermore, the multichannel needle release device further comprises a guide rod, the guide rod is arranged between the motor fixing plate and the gun arranging cavity, the upper end of the guide rod is connected with the motor fixing plate, the guide rod penetrates through the connecting plate, a bearing is arranged on the upper surface of the connecting plate, and the lower end of the guide rod is connected with the gun arranging cavity.
Further, the multichannel needle-releasing device further comprises a sealing cavity, the sealing cavity is arranged between the gun arranging cavity and the needle releasing plate, an air passage is formed in the sealing cavity, and the air passage is connected with the air passages of the channels.
Furthermore, the number of the channels of the multi-channel needle removal device is eight.
Further, the ladder that takes off the faller downside is eight layers, the ladder set up in on the horizontal direction axis of taking off the faller downside, set for first passageway ladder to last passageway ladder and be first to eighth passageway ladder respectively, eighth passageway ladder height is zero, seventh passageway ladder height is first to set for the height, the sixth passageway extremely every passageway ladder of first passageway increases progressively a first height of setting for, first passageway ladder height is seven first height of setting for.
Further, the first set height is 0.3-3 mm.
Furthermore, the multichannel needle removal device further comprises a photoelectric switch connecting plate, the photoelectric switch connecting plate is arranged on the front side and the rear side of the lower portion of the sealed cavity, a photoelectric switch is arranged on the photoelectric switch connecting plate, photoelectric switch separation blade notches are formed in the edges of the front side and the rear side of the needle removal plate, a photoelectric switch separation blade is arranged on the upper portion of the needle removal sleeve, and the photoelectric switch separation blade can be inserted into the photoelectric switch separation blade notch in the needle removal plate and is matched with the photoelectric switch arranged on the photoelectric switch detection plate for detecting the needle removal in place.
The invention also provides a needle removing method of the multi-channel needle removing device, which comprises the following steps:
a sample adding method of a multi-channel integrated sample adding device is characterized by being used for the multi-channel integrated sample adding device and comprising the following steps:
the multi-channel needle release device moves to a needle release area, an output shaft of the motor drives the connecting plate to move downwards, the connecting plate extrudes the needle release rod to move downwards, and the needle release rod drives the needle release plate to move downwards; when the motor drives the connecting plate to move downwards, the needle release rod and the needle release plate are automatically reset to the original positions by the aid of the springs sleeved on the needle release rod and the needle release plate.
The needle removing sleeve of the channel is pushed to move downwards in sequence from the first channel ladder to the last channel ladder on the lower side surface of the needle removing plate; the needle removing sleeves of the first channel and the last channel sequentially extrude the sample adding needles of the channels, and multi-channel automatic stepped needle removing is achieved.
Further, the needle removal method further comprises the following steps:
the needle removing sleeve of the channel is pushed to move downwards in sequence from the first channel ladder to the last channel ladder on the lower side surface of the needle removing plate; photoelectric switch blocking pieces on the needle release sleeves of the first channel and the last channel sequentially move out of the photoelectric switch detection range of the channel where the photoelectric switch blocking pieces are located, and multi-channel automatic stepped needle release in-place detection is achieved.
Compared with the prior art, the multichannel needle removing device comprises a motor, a motor fixing plate, a connecting plate, a gun arranging cavity, a needle removing plate, needle removing rods, an adapter and a needle removing sleeve, the multichannel needle removing device drives the connecting plate to move downwards through the motor, the needle removing rods on two sides are further extruded, the needle removing plate is driven to move downwards, the lower side surface of the needle removing plate is provided with steps with the same number as channels, the height of the steps from the first channel to the last channel is gradually reduced, multichannel automatic needle removing operation is achieved, the problems that in the prior art, detection is interrupted and efficiency is low due to high needle removing abnormal rate of multichannel needle removing operation are solved, and the problems that equipment is aged and has a high failure rate due to the fact that a driving module is overloaded and maintenance failure rate is high are solved. Compared with the prior art, the multi-channel automatic ladder-shaped needle removal operation can be realized, the needle removal abnormal rate is greatly reduced, the operation process is stable, and the working efficiency of nucleic acid extraction is greatly improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings can be obtained by those skilled in the art according to the drawings.
FIG. 1 is a schematic structural diagram of a multi-channel needle removal device according to an embodiment of the present invention;
FIG. 2 is an exploded view of a multi-channel needle release device according to an embodiment of the present invention;
FIG. 3 is a schematic view of a partial structure of a multi-channel needle removal device according to an embodiment of the present invention;
FIG. 4 is a side view of a stripper plate according to one embodiment of the present invention;
fig. 5 is a perspective view of a needle-off plate according to an embodiment of the invention.
Wherein, 100-multi-channel needle removing device, 110-motor, 111-motor fixing plate, 112-connecting frame, 113-motor output shaft, 114-guide rod, 115-bearing, 116-connecting plate, 117-oil sealing plate, 118-piston, 119-oil seal, 120-gun cavity, 121-needle removing rod, 122-spring, 123-needle removing plate, 124-sealing cavity, 125-photoelectric switch baffle, 126-photoelectric switch connecting plate, 127-photoelectric switch, 128-adapter, 129-needle removing sleeve, 130-disposable sample adding needle, 131-needle removing sleeve spring, 132-fastening bolt, 133-photoelectric switch baffle notch, 141-first channel ladder, 142-second channel ladder, 143-third channel ladder, 144-fourth channel step, 145-fifth channel step, 146-sixth channel step, 147-seventh channel step, 148-eighth channel step.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be further described with reference to the accompanying drawings. It is to be understood that the described embodiments are merely exemplary of the invention, and not restrictive of the full scope of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that all directional indicators (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the relative position relationship between the components, the motion situation, etc. in a specific posture, if the specific posture changes, the directional indicator changes accordingly.
As shown in fig. 1-2, a multi-channel needle removing device 100 includes a motor 110, a motor fixing plate 111, a connecting plate 112, a gun arranging cavity 120, a needle removing plate 123, a needle removing rod 121, an adapter 128 and a needle removing sleeve 129, wherein the motor 110 is disposed on the upper portion of the multi-channel needle removing device 100 through the motor fixing plate 111, a motor output shaft 113 is connected with the connecting plate 116, the gun arranging cavity 120 is connected with the motor fixing plate 111 through a connecting frame 112, the upper end of the needle removing rod 121 is connected with the connecting plate 116, the needle removing rod 123 penetrates through the gun arranging cavity 120, the lower end thereof is connected with the needle removing plate 123, the adapter 128 penetrates through the needle removing plate 123 to be connected with the gun arranging cavity 120, the needle removing sleeve 129 is sleeved on the adapter 128 and elastically connected with the needle removing plate 123, the lower side surface of the needle removing plate 123 has steps with the same number as the number of channels, and the heights of the first channel steps to the last channel steps are gradually decreased.
This multichannel device 100 that takes off needle passes through motor 110 drive connecting plate 112 downstream, and then extrudees both sides and takes off needle bar 121 to the drive takes off the faller 123 downstream, the downside of taking off the faller 123 has the ladder the same with the passageway number, the height of first passageway ladder to last passageway ladder decreases progressively, realizes multichannel automatic needle operation of taking off, solve among the prior art multichannel needle operation of taking off, the needle abnormal rate is high, lead to detecting the interrupt, the problem of inefficiency, and because the too heavy equipment aging fault that leads to of drive module load, the problem that the maintenance fault rate is high. Compared with the prior art, the multi-channel automatic ladder-shaped needle removal operation can be realized, the needle removal abnormal rate is greatly reduced, the operation process is stable, and the working efficiency of nucleic acid extraction is greatly improved.
As shown in FIGS. 1-2, a spring 122 is disposed at the upper end of the needle-removing rod 121 of the multi-channel needle-removing device 100, and the position of the spring 122 is between the connecting plate 116 and the gun-discharging chamber 120. The upper end of the needle releasing rod 121 is elastically connected with the connecting plate 116 through a spring 122. When the needle removing operation is required, the motor 110 drives the connecting plate 116 to move downwards, the connecting plate 116 compresses the needle removing rod 121, and when the spring 122 on the needle removing rod 121 is compressed to the maximum limit, that is, the connecting plate 116 abuts against the gun arranging cavity 120, the motor 110 is further driven, so that the connecting plate 116 further pushes the needle removing rod 121 to move downwards, and further drives the needle removing plate 123 to move downwards, and further the needle removing plate 123 pushes the needle removing sleeve on the adapter to move downwards, thereby completing the needle removing action. The downward movement process of the motor 110 driving the connecting plate 116 is divided into two stages: the first stage is that the connecting plate 116 moves downwards to abut against the gun discharging cavity 120 to overcome the elastic force on the needle releasing rod 121, and at the same time, the piston 118 between the connecting plate 116 and the gun discharging cavity 120 is compressed to increase the pressure in each channel and further to completely remove the liquid in each channel, and the second stage is that the motor 110 continues to drive the connecting plate 116 to move downwards, at this time, the spring on the needle releasing rod 121 is compressed to the limit, and under the continuous drive of the motor 110, the needle releasing rod 121 moves downwards, and further the needle releasing rod 121 pushes the needle releasing plate 123 connected with the needle releasing rod to move downwards, so that each channel step on the lower side surface of the needle releasing plate 123 pushes the needle releasing sleeve of each channel to move downwards, and the step needle releasing action is completed. The downward motion setting of two stages of this connecting plate 116 makes annotate the liquid and takes off the needle operation more coherent to ensure before taking off the needle that the liquid in each passageway application of sample needle is got rid of totally, avoid taking off the needle in-process test solution and splash and cause the pollution.
As shown in fig. 1-2, the multi-channel needle removing device 100 further includes a guide rod 114, the guide rod 114 is disposed between the motor fixing plate 111 and the gun arranging cavity 120, the upper end of the guide rod 114 is connected to the motor fixing plate 111, the guide rod 114 passes through the connecting plate 116, the guide rod 114 is provided with a bearing 115 on the upper surface of the connecting plate 116, and the lower end of the guide rod 114 is connected to the gun arranging cavity 120. The guide rod 114 is arranged to enable the downward movement of the connecting plate 116 in two stages to be more stable, and the multi-channel needle releasing device is prevented from being deformed by high-strength thrust output by a motor when a needle is released, so that the positions of all channels are deviated, and the needle releasing effect is further influenced. The guide rod 114 is provided with a bearing 115 on the upper surface of the connecting plate 116, so that the downward movement process of the connecting plate 116 is more stable, the compression process of the piston 118 is stable, and the liquid splashing in the liquid discharging process is avoided to cause pollution.
As shown in fig. 1-2, the multi-channel needle removing device 100 further includes a sealing cavity 124, the sealing cavity 124 is disposed between the gun discharging cavity 120 and the needle removing plate 123, and the sealing cavity 124 has air passages connected to the air passages of the respective channels. The sealing cavity 124 is arranged in an externally closed manner, and is internally provided with air passages for connecting each passage piston with the corresponding passage adapter, so that each passage forms a closed and communicated air passage of the piston passage-air passage-adapter passage, and the accurate operation of the suction and discharge process of liquid in each passage is ensured. On the other hand, because the multichannel piston of upper portion is 2 crisscross settings in front and back in the sealed intracavity, and the multichannel adapter is 1 row setting, and each channel piston and adapter are connected to the air flue of sealed intracavity 124, this connected mode makes multichannel device of taking off the needle compact structure, and space utilization is high, does benefit to the miniaturization of equipment.
As shown in FIGS. 1-2, in one embodiment, the number of channels of the multi-channel needle removal device 100 is eight channels. In general, a nucleic acid extractor is used in combination with a 96-well deep-well plate, which is generally 8 rows and 12 columns. The 8 channels of the multi-channel needle removing device 100 correspond to 8 holes in each row of the 96-hole deep hole plate, and needle removing operation of 8 sample adding needles can be completed in batches, so that the working efficiency is greatly improved. Of course, the multi-channel needle-removing device 100 can be set to 2-12 channels according to the actual experiment requirement, and the general concept of the invention is not affected.
As shown in fig. 1 to 5, in one embodiment, the number of the steps on the lower side of the stripper plate 123 is eight, the steps are arranged on the horizontal central axis of the lower side of the stripper plate 123, the first to last passage steps are respectively set as first to eighth passage steps, the eighth passage step 148 is zero in height, the seventh passage step 147 is a first set height, each passage step from the sixth passage to the first passage is increased by one first set height, and the first passage step 141 is seven first set heights. Because the needle removing sleeves sleeved on the adapters are arranged in a front-back two-row mode by taking the adapters as centers, the ladder is arranged on a horizontal central axis on the lower side surface of the needle removing plate 123, the needle removing sleeves on the front side and the back side below the needle removing plate 123 can be pushed, and therefore the needle removing operation of the sampling needles of all channels is achieved. The height of the eighth channel step 148 is zero, that is, the eighth channel step is the horizontal plane of the lower side surface of the needle releasing plate, and when the needle releasing plate 123 moves downwards to the horizontal plane of the lower side surface of the needle releasing plate to extrude the needle releasing sleeve of the eighth channel, the needle releasing of the eighth channel is realized. Seventh channel step 147 height is a first set height, sixth channel step 146 height is 2 first set heights, fifth channel step 145 height is 3 first set heights, fourth channel step 144 height is 4 first set heights, third channel step 143 height is 5 first set heights, second channel step 142 height is 6 first set heights, first channel step 141 height is 7 first set heights. That is, the first channel step is reduced by 1 first set height to the last channel step once, in the downward movement process of the needle release plate 123, each channel step on the lower side surface of the needle release plate 123 is sequentially contacted with a needle release sleeve for pushing the channel, the automatic sequential needle release operation of the sample adding needles of each channel is realized, the same time is realized, the motor only carries out the needle release operation on the sample adding needle of one channel, the driving force of the motor can completely meet the needle release requirement of one channel, the needle release failure phenomenon of the multi-channel needle release device is greatly reduced, the experiment suspension phenomenon caused by the needle release failure is prevented, the experiment efficiency is improved, the motor of the step automatic needle release device cannot have the condition of overweight load, the motor aging and the failure caused by frequent operation are avoided, and the maintenance cost of the equipment is reduced.
As shown in fig. 1-5, in one embodiment, the first set height is 0.3-3 mm. The height of the range can ensure that the sample adding needle connected to the adapter can realize needle removal under the pushing of the needle removing sleeve. For example, when the first set height is 0.5mm, the first channel step 141 is 3.5mm in height, the second channel step 142 is 3mm in height, the third channel step 143 is 2.5mm in height, the fourth channel step 144 is 2mm in height, the fifth channel step 145 is 1.5mm in height, the sixth channel step 146 is 1mm in height, the seventh channel step 147 is 0.5mm in height, and the eighth channel step 148 is 0 in height. Of course, this first height of setting can be adjusted according to the needle pulling driving force of reality and application of sample needle frictional force, is guaranteeing that the application of sample needle is taken off under the circumstances of going smoothly, and the first height of setting of minimizing makes multichannel needle pulling device compact structure, does benefit to the miniaturization of equipment.
As shown in fig. 1-2, the multi-channel needle removing device 100 further includes a photoelectric switch connecting plate 126, the photoelectric switch connecting plate 126 is disposed on the front and rear sides of the lower portion of the sealing cavity 124, the photoelectric switch connecting plate 126 is provided with a photoelectric switch 127, edges of the front and rear sides of the needle removing plate 123 are provided with photoelectric switch barrier notches 133, the upper portion of the needle removing sleeve 129 is provided with a photoelectric switch barrier 125, the photoelectric switch barrier 125 can be inserted into the photoelectric switch barrier notch 133 on the needle removing plate 123, and is matched with the photoelectric switch 127 disposed on the photoelectric switch connecting plate 126 for detecting the needle removing in place. The needle removing sleeve 129 is sleeved on the adapter 128 and fixedly arranged in the front row and the rear row of the adapter 128 in a staggered mode through the fastening bolts 132, the fastening bolts 132 are sleeved with the springs 122, the upper portion of the needle removing sleeve 129 is provided with the photoelectric switch blocking piece 125, the photoelectric switch blocking piece 125 can be inserted into the photoelectric switch blocking piece notch 133 on the needle removing plate 123 and is matched with the photoelectric switch 127 arranged on the photoelectric switch connecting plate 126, when the photoelectric switch blocking piece 125 on the needle removing sleeve 129 leaves the detection range of the photoelectric switch 127, namely after the lower channel surface of the needle removing plate 123 pushes the needle removing sleeve of each channel to carry out needle removing operation in place, the photoelectric switch 127 in the channel does not have a sensing signal, and therefore multichannel needle removing in place detection is achieved.
This multichannel integration application of sample device 100 still includes controlling means, and controlling means is connected with subassembly electricity such as motor 110, photoelectric switch 127 respectively for send the motion instruction of each module, receive photoelectric switch's detected signal, contrast detected signal, when the signal is unusual, send the suggestion of abnormal information.
The invention also provides a needle removing method of the multi-channel needle removing device, which adopts the multi-channel needle removing device and comprises the following steps:
when the multi-channel needle release device 100 moves to a needle release area, the output shaft 113 of the motor drives the connecting plate 116 to move downwards, the connecting plate 116 presses the needle release rod 121 to move downwards, and the needle release rod 121 drives the needle release plate 123 to move downwards; the needle release sleeve 129 of the channel is pushed to move downwards in sequence from the first channel step to the last channel step on the lower side surface of the needle release plate 123; the needle removing sleeves of the first channel and the last channel sequentially extrude the sample adding needles of the channels, and multi-channel automatic stepped needle removing is achieved. The first channel ladder is reduced by 1 first set height to the last channel ladder once, the sample adding needles of all channels are automatically and sequentially subjected to needle removing operation, at the same time, the motor only performs needle removing operation on the sample adding needles of one channel, the motor driving force can completely meet the needle removing requirement of one channel, the needle removing failure phenomenon of the multi-channel needle removing device is greatly reduced, the phenomenon that the experiment is stopped due to needle removing failure is prevented from occurring, the experiment efficiency is improved, the motor of the ladder automatic needle removing device cannot generate the condition of overweight load, the motor aging and the failure caused by frequent operation are avoided, and the equipment maintenance cost is reduced.
Further, the needle removing method of the multi-channel needle removing device is characterized by further comprising the following steps:
the needle removing sleeve of the channel is pushed to move downwards in sequence from the first channel ladder to the last channel ladder on the lower side surface of the needle removing plate; photoelectric switch blocking pieces on the needle release sleeves of the first channel and the last channel sequentially move out of the photoelectric switch detection range of the channel where the photoelectric switch blocking pieces are located, and multi-channel automatic stepped needle release in-place detection is achieved. The in-place detection of the needle release can be realized through each channel, and the detection accuracy is high. After the needle is removed, if a certain channel still detects the induction signal of the photoelectric switch, the channel is prompted to fail to remove the needle, the control device sends out the channel needle removal abnormal information prompt, and the needle removal condition of each channel can be accurately detected.
The applicant asserts that the above-described embodiments merely represent the basic principles, principal features and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are merely illustrative of the principles of the invention, and that various changes and modifications can be made by one skilled in the art without departing from the spirit and scope of the invention, which will fall within the scope of the invention as claimed.
The present invention is not limited to the above embodiments, and all embodiments adopting the similar structure and method to achieve the object of the present invention are within the protection scope of the present invention.
Claims (10)
1. The utility model provides a needle device is taken off to multichannel, its characterized in that includes motor, motor fixed plate, connecting plate, row's rifle cavity, takes off the faller, takes off the needle bar, adapter and takes off the needle cover, the motor sets up in the upper portion that the needle device was taken off to the multichannel through the motor fixed plate, the output shaft of motor with the connecting plate is connected, row's rifle cavity pass through the linking frame with the motor fixed plate is connected, take off the upper end of needle bar and connect the connecting plate, take off the needle bar and pass row's rifle cavity, its lower extreme with it is connected to take off the faller, the adapter passes take off the faller with row's rifle cavity is connected, it locates to take off the needle cover the adapter with take off faller elastic connection, the downside that takes off the faller has the ladder the same with the channel number, and the height of first passageway ladder to last passageway ladder progressively diminishes in proper order.
2. The multi-channel needle removing device as claimed in claim 1, wherein a spring is sleeved on the upper end of the needle removing rod, and the position of the spring is between the connecting plate and the gun arranging cavity.
3. The multi-channel needle removing device as claimed in claim 2, further comprising a guide rod disposed between the motor fixing plate and the gun arranging cavity, wherein the upper end of the guide rod is connected to the motor fixing plate, the guide rod passes through the connecting plate, the guide rod is provided with a bearing on the upper surface of the connecting plate, and the lower end of the guide rod is connected to the gun arranging cavity.
4. The multi-channel needle removing device as claimed in claim 3, further comprising a sealing cavity, wherein the sealing cavity is arranged between the gun arranging cavity and the needle removing plate, and air passages are arranged in the sealing cavity and connected with the air passages of the channels.
5. The multiple channel needle removal device of claim 4, wherein the number of channels of the multiple channel needle removal device is eight channels.
6. A multi-channel needle-releasing device as claimed in claim 5, wherein the steps on the lower side of the needle-releasing plate are eight layers, the steps are arranged on the horizontal central axis of the lower side of the needle-releasing plate, the first channel step to the last channel step are set to be the first to the eighth channel steps, the eighth channel step is zero in height, the seventh channel step is the first set height, each of the sixth channel to the first channel step is increased by one first set height, and the first channel step is seven first set heights.
7. A multiple needle release device according to claim 6, wherein the first predetermined height is 0.3-3 mm.
8. The multi-channel needle removal device according to claim 7, further comprising a photoelectric switch connecting plate, wherein the photoelectric switch connecting plate is disposed on the front side and the rear side of the lower portion of the sealing cavity, the photoelectric switch is disposed on the photoelectric switch connecting plate, photoelectric switch blocking piece notches are disposed on the edges of the front side and the rear side of the needle removal plate, a photoelectric switch blocking piece is disposed on the upper portion of the needle removal sleeve, and the photoelectric switch blocking piece can be inserted into the photoelectric switch blocking piece notch on the needle removal plate and is matched with the photoelectric switch disposed on the photoelectric switch connecting plate for detecting the needle removal in place.
9. A needle release method of a multichannel needle release device, which is used for the multichannel needle release device of claims 1 to 8, and comprises the following steps:
the multi-channel needle release device moves to a needle release area, an output shaft of a motor drives a connecting plate to move downwards, the connecting plate extrudes the needle release rod to move downwards, and the needle release rod drives a needle release plate to move downwards; when the motor drives the connecting plate to move downwards, the needle release rod and the needle release plate are automatically reset to the original position by the spring sleeved on the needle release rod and the needle release plate;
the needle removing sleeve of the channel is pushed to move downwards in sequence from the first channel ladder to the last channel ladder on the lower side surface of the needle removing plate; the needle removing sleeves of the first channel and the last channel sequentially extrude the sample adding needles of the channels, and multi-channel automatic stepped needle removing is achieved.
10. The needle removing method of the multichannel needle removing device as claimed in claim 9, wherein the needle removing method further comprises the steps of:
the needle removing sleeve of the channel is pushed to move downwards in sequence from the first channel ladder to the last channel ladder on the lower side surface of the needle removing plate; photoelectric switch blocking pieces on the needle release sleeves of the first channel and the last channel sequentially move out of the photoelectric switch detection range of the channel where the photoelectric switch blocking pieces are located, and multi-channel automatic stepped needle release in-place detection is achieved.
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| CN202210205337.0A CN114849807A (en) | 2022-03-02 | 2022-03-02 | Multi-channel needle release device and needle release method |
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| CN202210205337.0A CN114849807A (en) | 2022-03-02 | 2022-03-02 | Multi-channel needle release device and needle release method |
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| CN202210205337.0A Pending CN114849807A (en) | 2022-03-02 | 2022-03-02 | Multi-channel needle release device and needle release method |
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