CN114848547A - 一种具有蜡质透气微通道的皮脂膜组合物及其制备方法 - Google Patents
一种具有蜡质透气微通道的皮脂膜组合物及其制备方法 Download PDFInfo
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Abstract
本发明提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，属于日用化学品与皮肤医学领域。所述组合物按重量份数计，包括如下组分：生物蜡10‑50份，天然表面活性剂5‑20份，润肤剂30‑85份。制备方法包括以下步骤：称取生物蜡、天然表面活性剂和润肤剂，将生物蜡与天然表面活性剂在40‑110℃条件下搅拌混合10‑30分钟，冷却至室温后，加入润肤剂搅拌混合30‑60分钟，得到具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。本发明提供的组合物选材为纯天然生物物质，对皮肤友好安全，仿生性能好，制备工艺简单温和，透气性好。
Description
技术领域
本发明属于日用化学品与皮肤医学领域,特别是涉及一种具有蜡质透气微通道的皮脂膜组合物及其制备方法。
背景技术
皮脂膜是由皮脂腺分泌的皮脂、角质细胞崩解产生的脂质、汗腺分泌的汗液，以一定比例融合在皮肤角质层表面乳化形成的一层保护膜。皮脂膜对皮肤有着重要的生理功能，可以有效滋润皮肤，并帮助锁住皮肤水分，使皮肤保持湿润和柔韧状态；并能防止外界水分及某些物质大量渗透进入人体。而皮肤的透气是通过微米级毛孔实现的，保持毛孔的透气畅通则是护肤品的基本要求。但是现有的皮脂仿生组合物化妆品，配方大都以油性成分为主，基本上就是在皮肤表面涂一层油，虽然与皮肤物质有一定的相容性，但由于其实质上是封闭性保湿，对于一些皮脂腺较旺盛的皮肤类型反而会堵塞毛孔，成为皮肤的负担。
如中国专利号CN109846757A公开了一种皮脂仿生组合物及包含其的化妆品，所述皮脂仿生组合物包括霍霍巴油、刺阿干树仁油、沙棘果油、植物角鲨烷和白池花籽油等组分。又如中国专利号CN111557874A公开了一种皮脂膜修复配方，含角鲨烯、脂肪酸甘油三酯、胆固醇等组分。这些发明的透气性不是很好，因此，本发明提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，以解决皮脂膜透气性不是很好的问题。
发明内容
本发明的目的是针对现有技术中皮脂膜透气性不好的问题，提供一种具有蜡质透气微通道的皮脂膜组合物及其制备方法。
为达以上目的，具体方案如下：
一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，按重量份数计，包括如下组分：生物蜡10-50份，天然表面活性剂5-20份，润肤剂30-85份。
优选的，所述生物蜡为棕榈蜡、蜂蜡、鲸蜡、鲸蜡硬脂酸、羊毛蜡、米糠蜡和葵花蜡中的一种或几种。
优选的，所述天然表面活性剂为茶皂素、卵磷脂、胆甾醇、山梨糖醇脂肪酸酯和甜菜碱中的一种或几种。
优选的，所述润肤剂按重量份数计有以下两种组分：
（1）植源性不饱和脂肪酸油70-90份，角鲨烯5-20份和维生素E5-25份；
（2）植源性不饱和脂肪酸油20-50份，角鲨烯1-5份，甘油5-10份，神经酰胺1-5份和山茶花鲜萃水30-73份。
所述植源性不饱和脂肪酸油为橄榄油、茶油、霍霍巴油、亚麻籽油、葵花籽油和白池花籽油中的一种或几种。
优选的，形成的透气微通道尺寸为10-900nm。
本发明第二方面提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法的制备方法，包括以下步骤：
称取生物蜡、天然表面活性剂和润肤剂，将生物蜡与天然表面活性剂在40-110℃条件下搅拌混合10-30分钟，冷却至室温后，加入润肤剂搅拌混合30-60分钟，得到具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
与现有技术相比，本发明具有如下有益效果：
本发明提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，在组合物体系中，生物蜡在天然表面活性剂作用下自组装聚集为格栅网络，其空隙尺寸为10-900nm，未施用于皮肤时，其空隙浸润着润肤剂，当组合物施用于皮肤表面时，由于润肤剂被皮肤吸收，会形成蜡质透气微通道，从而具备良好的透气性，同时本发明组合物成分为纯天然生物物质，对皮肤友好安全，仿生性能好，制备工艺简。
附图说明
图1,为本发明的蜡质透气微通道的电镜图。
具体实施方式
下面结合具体实施例对本发明进行详细说明。以下实施例将有助于本领域的技术人员进一步理解本发明，但不以任何形式限制本发明。应当指出的是，对本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变化和改进,包括各实例间的任意组合。
实施例1
本实施例提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，按重量份数计，其组分如下：棕榈蜡30份，茶皂素10份，润肤剂60份。
其中润肤剂按重量份数计，其组分如下：茶油80份，角鲨烯10份，维生素E10份。
制备方法如下：将棕榈蜡与茶皂素在90℃条件下搅拌混合20分钟，冷却至室温后，加入润肤剂搅拌混合45分钟，得到具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
采用扫描电子显微镜观察，该仿生皮脂膜组合物形成微通道的平均尺寸为50nm，具体见附图1。
实施例2
本实施例提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，按重量份数计，其组分如下：蜂蜡50份，卵磷脂20份，润肤剂30份。
其中润肤剂按重量份数计，其组分如下：茶油90份，角鲨烯5份，维生素E5份。
制备方法如下：将蜂蜡与卵磷脂在90℃条件下搅拌混合30分钟，冷却至室温后，加入润肤剂搅拌混合60分钟，得到所述具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
采用扫描电子显微镜观察，该仿生皮脂膜组合物形成微通道的平均尺寸为10nm。
实施例3
本实施例提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，按重量份数计，其组分如下：鲸蜡10份，茶皂素5份，润肤剂85份。
其中润肤剂按重量份数计，其组分如下：霍霍巴油50份，角鲨烯5份，甘油10份，神经酰胺5份，山茶花鲜萃水30份。
制备方法如下：将鲸蜡与茶皂素在40℃条件下搅拌混合10分钟，冷却至室温后，加入润肤剂搅拌混合30分钟，得到所述具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
采用扫描电子显微镜观察，该仿生皮脂膜组合物形成微通道的平均尺寸为200nm。
实施例4
本实施例提供了一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，按重量份数计，其组分如下：米糠蜡30份，山梨糖醇脂肪酸酯10份，润肤剂60份。
其中润肤剂按重量份数计，其组分如下：亚麻籽油20份，角鲨烯1份，甘油5份，神经酰胺1份，山茶花鲜萃水73份。
制备方法如下：将米糠蜡与山梨糖醇脂肪酸酯在80℃条件下搅拌混合15分钟，冷却至室温后，加入润肤剂搅拌混合40分钟，得到所述具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
采用扫描电子显微镜观察，该仿生皮脂膜组合物形成微通道的平均尺寸为800nm。
对比例1
将30份重量份的棕榈蜡在90℃条件下搅拌20分钟，加入70份重量份的润肤剂，搅拌混合45分钟，冷却至室温后，采用扫描电子显微镜观察，该组合物为连续相态，不能形成纳米尺度的微通道。
其中润肤剂按重量份数计，其组分如下：橄榄油80份，角鲨烯10份，维生素10份。
对比例2
将10份重量份的鲸蜡在40℃条件下搅拌10分钟，加入90份重量份的润肤剂搅拌混合30分钟，冷却至室温后，采用扫描电子显微镜观察，该组合物为不连续破裂膜状态，空隙尺度大于500μm。
其中，润肤剂按重量份数计，其组分如下：霍霍巴油份50份，角鲨烯5份，甘油10份，神经酰胺5份和山茶花鲜萃水30份。
以上所述仅为本发明的实施例，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明技术原理的前提下，可以对这些实施例进行多种变化、修改、替换和变型，这些变化、修改、替换和变型，也应视为本发明的保护范围。
Claims (7)
1.一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，按重量份数计，包括如下组分：生物蜡10-50份，天然表面活性剂5-20份，润肤剂30-85份。
2.根据权利要求1所述的一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，所述生物蜡为棕榈蜡、蜂蜡、鲸蜡、鲸蜡硬脂酸、羊毛蜡、米糠蜡和葵花蜡中的一种或几种。
3.根据权利要求1所述的一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，所述天然表面活性剂为茶皂素、卵磷脂、胆甾醇、山梨糖醇脂肪酸酯和甜菜碱中的一种或几种。
4.根据权利要求1所述的一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，所述润肤剂按重量份数计有以下两种组分：
（1）植源性不饱和脂肪酸油70-90份，角鲨烯5-20份和维生素E5-25份；
（2）植源性不饱和脂肪酸油20-50份，角鲨烯1-5份，甘油5-10份，神经酰胺1-5份和山茶花鲜萃水30-73份。
5.所述植源性不饱和脂肪酸油为橄榄油、茶油、霍霍巴油、亚麻籽油、葵花籽油和白池花籽油中的一种或几种。
6.根据权利要求1所述的一种具有蜡质透气微通道的皮脂膜组合物及其制备方法，其特征在于，形成的透气微通道尺寸为10-900nm。
7.一种根据权利要求1-4中任一项所述的具有蜡质透气微通道的皮脂膜组合物及其制备方法的制备方法，其特征在于，所述制备方法包括以下步骤：
称取生物蜡、天然表面活性剂和润肤剂，将生物蜡与天然表面活性剂在40-110℃条件下搅拌混合10-30分钟，冷却至室温后，加入润肤剂搅拌混合30-60分钟，得到具有构建蜡质透气微通道性能的天然仿生皮脂膜组合物。
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