CN114828948A - 用于热阻断神经的设备 - Google Patents

用于热阻断神经的设备 Download PDF

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Publication number
CN114828948A
CN114828948A CN202080088377.0A CN202080088377A CN114828948A CN 114828948 A CN114828948 A CN 114828948A CN 202080088377 A CN202080088377 A CN 202080088377A CN 114828948 A CN114828948 A CN 114828948A
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China
Prior art keywords
temperature
thermal
thermal energy
nerve
applicator
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Pending
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CN202080088377.0A
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English (en)
Chinese (zh)
Inventor
S·R·波皮尔拉斯基
G·M·查普曼
C·泰
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Sermaquan Co ltd
University of Pittsburgh
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Sermaquan Co ltd
University of Pittsburgh
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Publication of CN114828948A publication Critical patent/CN114828948A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00434—Neural system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A61F2007/0029—Arm or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A61F2007/0029—Arm or parts thereof
    • A61F2007/0036—Hand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0093—Heating or cooling appliances for medical or therapeutic treatment of the human body programmed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
    • A61F2007/0096—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator with a thermometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0295—Compresses or poultices for effecting heating or cooling for heating or cooling or use at more than one temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0295—Compresses or poultices for effecting heating or cooling for heating or cooling or use at more than one temperature
    • A61F2007/0296—Intervals of heating alternated with intervals of cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
CN202080088377.0A 2019-12-18 2020-12-17 用于热阻断神经的设备 Pending CN114828948A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962949969P 2019-12-18 2019-12-18
US62/949,969 2019-12-18
PCT/US2020/065636 WO2021127195A1 (en) 2019-12-18 2020-12-17 Apparatus for thermal blockade of nerves

Publications (1)

Publication Number Publication Date
CN114828948A true CN114828948A (zh) 2022-07-29

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CN202080088377.0A Pending CN114828948A (zh) 2019-12-18 2020-12-17 用于热阻断神经的设备

Country Status (7)

Country Link
EP (2) EP4076632B1 (https=)
JP (1) JP2023507066A (https=)
CN (1) CN114828948A (https=)
AU (1) AU2020405088A1 (https=)
BR (1) BR112022011743A2 (https=)
CA (1) CA3161124A1 (https=)
WO (1) WO2021127195A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12370079B2 (en) 2018-06-19 2025-07-29 Thermaquil, Inc. Apparatus and method for thermal blockade of nerves
WO2023075912A1 (en) * 2021-10-28 2023-05-04 Case Western Reserve University Systems and methods for selective heat-induced neuromodulation

Citations (8)

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WO2013163469A1 (en) * 2012-04-27 2013-10-31 Medtronic Ardian Luxembourg Sarl Therapy systems including hyperthermic energy delivery elements and cryogenic applicators and associated methods
US20140228900A1 (en) * 2013-02-13 2014-08-14 Flint Hills Scientific, Llc Selective recruitment and activation of fiber types in nerves for the control of undesirable brain state changes
US20140277302A1 (en) * 2013-03-14 2014-09-18 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US20150265459A1 (en) * 2014-02-21 2015-09-24 Circuit Therapeutics, Inc. System and method for therapeutic management of unproductive cough
CN107921237A (zh) * 2015-04-27 2018-04-17 反射医学公司 交感神经心肺神经调节系统和方法
CN108290023A (zh) * 2015-12-03 2018-07-17 匹兹堡大学 适用于通过局部冷却到室温来进行神经阻断的设备和方法
US20180207450A1 (en) * 2016-10-04 2018-07-26 Aucta Technologies Inc. Devices and methods for selectively activating afferent nerve fibers
CN109843160A (zh) * 2016-07-29 2019-06-04 阿克松疗法公司 通过脏神经消融术治疗心脏衰竭的装置、系统和方法

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US6074414A (en) * 1998-08-06 2000-06-13 Limex Bio-Tech L.C. System for providing thermal application to external body areas of a patient
WO2008042667A2 (en) 2006-09-29 2008-04-10 Aspen Compressor, Llc Orientation and gravity insensitive in-casing oil management system
US9283109B2 (en) * 2007-03-16 2016-03-15 Innovative Medical Equipment, Llc Fluid manipulating device and tissue interacting device for a thermal therapy system
CN104519949B (zh) * 2012-05-09 2017-03-29 梅多克有限公司 改进的热刺激探测器以及热刺激方法
WO2015142838A1 (en) * 2014-03-18 2015-09-24 Case Western Reserve University Systems and methods for fast and reversible nerve block
WO2016149117A1 (en) 2015-03-13 2016-09-22 Embr Labs Inc. Methods and apparatuses for manipulating temperature

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WO2013163469A1 (en) * 2012-04-27 2013-10-31 Medtronic Ardian Luxembourg Sarl Therapy systems including hyperthermic energy delivery elements and cryogenic applicators and associated methods
US20140228900A1 (en) * 2013-02-13 2014-08-14 Flint Hills Scientific, Llc Selective recruitment and activation of fiber types in nerves for the control of undesirable brain state changes
US20140277302A1 (en) * 2013-03-14 2014-09-18 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US20150265459A1 (en) * 2014-02-21 2015-09-24 Circuit Therapeutics, Inc. System and method for therapeutic management of unproductive cough
CN107921237A (zh) * 2015-04-27 2018-04-17 反射医学公司 交感神经心肺神经调节系统和方法
CN108290023A (zh) * 2015-12-03 2018-07-17 匹兹堡大学 适用于通过局部冷却到室温来进行神经阻断的设备和方法
CN109843160A (zh) * 2016-07-29 2019-06-04 阿克松疗法公司 通过脏神经消融术治疗心脏衰竭的装置、系统和方法
US20180207450A1 (en) * 2016-10-04 2018-07-26 Aucta Technologies Inc. Devices and methods for selectively activating afferent nerve fibers

Non-Patent Citations (1)

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Title
ZHAOCUN ZHANG等: "Conduction block of mammalian myelinated nerve by local cooling to 15–30°C after a brief heating", 《JOURNAL OF NEUROPHYSIOLOGY》, vol. 115, no. 3, 6 January 2016 (2016-01-06), pages 1436 - 1445, XP055595881, DOI: 10.1152/jn.00954.2015 *

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Publication number Publication date
EP4076632B1 (en) 2024-02-07
CA3161124A1 (en) 2021-06-24
EP4385557A3 (en) 2024-08-21
EP4076632A1 (en) 2022-10-26
BR112022011743A2 (pt) 2022-08-30
WO2021127195A1 (en) 2021-06-24
AU2020405088A1 (en) 2022-05-19
EP4385557A2 (en) 2024-06-19
JP2023507066A (ja) 2023-02-21

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