CN114755438A - Full-automatic biochemical analyzer - Google Patents

Full-automatic biochemical analyzer Download PDF

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Publication number
CN114755438A
CN114755438A CN202210666332.8A CN202210666332A CN114755438A CN 114755438 A CN114755438 A CN 114755438A CN 202210666332 A CN202210666332 A CN 202210666332A CN 114755438 A CN114755438 A CN 114755438A
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China
Prior art keywords
sample
needle
reagent
cleaning
hand
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CN202210666332.8A
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Chinese (zh)
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CN114755438B (en
Inventor
许行尚
杰弗瑞·陈
胡统号
郭金龙
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Suzhou Aikeruite Biomedical Technology Co ltd
Nanjing Lanyu Biological Technology Co Ltd
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Suzhou Aikeruite Biomedical Technology Co ltd
Nanjing Lanyu Biological Technology Co Ltd
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Priority to CN202210986481.2A priority Critical patent/CN115356494A/en
Priority to CN202210666332.8A priority patent/CN114755438B/en
Publication of CN114755438A publication Critical patent/CN114755438A/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G01N35/0095—Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a full-automatic biochemical analyzer, which comprises a sample introduction module, a sample filling module, a reagent filling module, a reaction and detection module, a stirring and mixing module and a reaction cup cleaning module; the sample filling module, the reagent filling module, the reaction and detection module, the stirring and mixing module and the reaction cup cleaning module are all arranged on the base; the sample injection module conveys a sample to be detected to a preset sampling position, and the sample to be detected is moved to the reaction and detection module for detection through the sample filling module; the reagent filling module is used for filling a reagent into a sample to be detected, the stirring and mixing module is used for stirring and mixing the sample to be detected and the reagent, and the reaction cup cleaning module is used for cleaning the reaction cup. The sample introduction module selectively conveys a sample to be detected to a preset sampling position, so that the operation mode of the sample introduction module is relatively independent, the sample introduction module can be adapted to other detection instruments, and the sample detection is carried out in a production line manner.

Description

Full-automatic biochemical analyzer
Technical Field
The invention belongs to the technical field of biochemical analysis and detection, and particularly relates to a full-automatic biochemical analyzer.
Background
Biochemical analyzers, also commonly referred to as biochemics, are instruments that use the principle of optoelectric colorimetry to measure a particular chemical component in a body fluid. Because of its fast measuring speed, high accuracy and small reagent consumption, it is widely used in hospitals, epidemic prevention stations and family planning service stations. The efficiency and the income of the conventional biochemical test can be greatly improved by matching the use.
Since the first full-automatic biochemical analyzer in the world was successfully produced by the U.S. Technicon corporation in 1957, the full-automatic biochemical analyzers with different models and functions are emerging continuously, which is a very important step for the automation of clinical biochemical tests in hospitals. Since the first introduction of the principle of a clinical biochemical analyzer in skeggs in the 50 s, along with the development of scientific technology, especially medical science, various biochemical automatic analyzers and diagnostic reagents have been developed greatly, and according to the structural principle of the analyzer, the analyzer can be divided into: continuous flow (pipeline), discrete, separated and dry sheet.
Chinese patent document CN110208559A discloses a biochemical analyzer, which includes a frame, a detection mechanism for detecting a sample, a sample transfer mechanism for loading the sample onto the detection mechanism, and a reagent loading mechanism for adding a reaction reagent into the detection mechanism; the sample conveying mechanism comprises a test tube rack, a conveying frame, a feeding area for feeding, a material taking area for the detection mechanism to absorb materials in the test tube, a discharging area for discharging and a material moving device for moving the test tube rack; the feeding area, the blanking area, the material taking area and the material moving device are all arranged on the rack; the upper reagent mechanism comprises a reagent cylinder which is rotationally connected with the rack, a plurality of reagent boxes which are arranged on the reagent cylinder, a reagent rotating device which enables the reagent cylinder to rotate, and an upper reagent device which is used for feeding the reagents in the reagent boxes to the detection mechanism; the detection mechanism comprises a reaction disc rotatably connected with the rack, a plurality of reaction cups arranged on the reaction disc, a reaction rotating device for rotating the reaction disc, a stirring device for stirring samples in the reaction cups, an optical detection device for detecting the samples stirred by the stirring device and a cleaning device for cleaning the reaction cups; the rotating device, the stirring device, the optical detection device and the cleaning device are all arranged on the rack.
The practical use effect of sample transmission mechanism is unsatisfactory among biochemical analyzer in the in-service use of above-mentioned technical scheme, especially to sample transmission mechanism's structural style and operation, can't adapt to full-automatic, and can't carry out seamless connection matching sampling with other instruments.
Disclosure of Invention
The invention aims to solve the technical problem of providing a biochemical analyzer which selectively conveys a sample to be detected to a preset sampling position, expands the matching degree of a sample introduction module and other detection platforms and improves the independence of the sample introduction module.
In order to solve the technical problem, the invention adopts the technical scheme that the full-automatic biochemical analyzer comprises a sample introduction module, a sample filling module, a reagent filling module, a reaction and detection module, a stirring and mixing module and a reaction cup cleaning module; the sample filling module, the reagent filling module, the reaction and detection module, the stirring and mixing module and the reaction cup cleaning module are all arranged on the base; the sample injection module conveys a sample to be detected to a preset sampling position, and the sample to be detected is moved to the reaction and detection module for detection through the sample filling module; the reagent filling module is used for filling a reagent into a sample to be detected, the stirring and mixing module is used for stirring and mixing the sample to be detected and the reagent, and the reaction cup cleaning module is used for cleaning the reaction cup.
In the above technical solution, the sample module transfers the sample to be detected to a preset sampling position, that is, the sample module transfers the sample to be detected to the preset sampling position according to the requirement of the sample to be detected, so that the operation mode of the sample module is relatively independent, the sampling position is not only the full-automatic biochemical analyzer of the present invention but also other detecting instruments, that is, the sample module can be adapted to other detecting instruments, and the sample detection is performed in a pipeline manner, for example, the sample can be matched with other detecting instrument platforms for sampling (for seamless connection with other instruments for sampling) after being transferred out in the full-automatic biochemical analyzer of the present invention, and the detection such as chemiluminescence and fluorescence immunoassay technology platform can be performed, if the sample does not need to be detected by one instrument, the sample is transferred by the sample module, and directly reaches the preset sampling position of the instrument to be detected by skipping the instrument, realizing full-automatic sample introduction; it should be emphasized that the sample introduction module in other existing analyzers does not match and detect the sample introduction module with other detection instrument platforms, but the sample introduction module is a preset sampling position when conveying a sample to be detected, and conveys the sample to be detected to an instrument to be detected, specifically, the sample introduction module can selectively convey the sample to be detected to different sampling positions according to the detection requirement of the sample to be detected, so that the matching degree of the sample introduction module and other detection platforms is increased, and the independence of the sample introduction module is improved.
Preferably, the sample introduction module and the base are mutually independent, so that the adaptability of the sample introduction module is expanded; the sample introduction module comprises a sample rack, and at least one sample tube is placed on the sample rack; the sample rack is driven by the sample inlet and outlet conveying assembly to carry out conveying action; the sampling module is also provided with a sampling assembly and a sampling shifting handle assembly, wherein the sampling assembly is right for sampling the sample frame, and the sampling shifting handle assembly is right for shifting the sample frame.
The sample introduction module and the base are mutually independent, so that the operation mode of the sample introduction module is relatively independent structurally, and the sample to be detected is more conveniently conveyed to a sampling position; the sample feeding module can be better matched with other instruments in structure, and particularly can be better connected when a sample to be detected is conveyed.
Preferably, the sample inlet and outlet conveying assembly comprises a sample inlet and outlet conveying belt, and the sample rack is placed on the sample inlet and outlet conveying belt; the sample inlet and outlet conveying belt is driven by a sample inlet and outlet conveying motor, the sample inlet and outlet conveying motor drives a sample inlet and outlet conveying driving wheel to rotate, and the sample inlet and outlet conveying driving wheel drives a sample inlet and outlet synchronizing wheel I, a sample inlet and outlet synchronizing wheel II and a sample inlet and outlet synchronizing wheel III to rotate through the sample inlet and outlet conveying belt.
The sample rack is placed on the sample inlet and outlet conveying belt and is conveyed along with the sample inlet and outlet conveying belt; the sample inlet and outlet synchronizing wheel I, the sample inlet and outlet synchronizing wheel II and the sample inlet and outlet synchronizing wheel III play roles in improving the spatial position and tensioning and supporting a sample inlet and outlet conveying belt.
Preferably, the sample feeding assembly comprises a sample feeding track changing push handle assembly and a sample feeding shifting handle assembly, the sample feeding track changing push handle assembly is provided with a sample feeding track changing push handle, and the sample feeding shifting handle assembly is provided with a sample feeding shifting handle; the sample injection track-changing push handle pushes the sample rack positioned on the sample inlet and outlet conveying belt into the movable range of the sample injection hand stirring component, and then the sample injection hand stirring the sample rack into the movable range of the sampling hand stirring component.
The sample introduction track-changing pushing hand pushes the sample rack away from the sample inlet and outlet conveying belt, and then the sample introduction operation is carried out by the sample introduction shifting hand.
Preferably, the sample introduction track-changing push hand is connected with a sample introduction track-changing push hand sliding block, and the sample introduction track-changing push hand sliding block moves along a sample introduction track-changing push hand sliding rail; the sample introduction track transfer push hand sliding block is connected with a sample introduction track transfer push hand belt through a sample introduction track transfer push hand belt connecting piece; the sample introduction track-changing push handle motor drives a sample introduction track-changing push handle driving wheel to rotate, and the sample introduction track-changing push handle driving wheel drives a sample introduction track-changing push handle driven wheel to rotate through the sample introduction track-changing push handle belt.
The belt of the sample introduction track changing push handle rotates to drive the sample introduction track changing push handle to move, and the sample introduction track changing push handle can push the sample rack into the moving range of the sample introduction shifting handle.
Preferably, the sample introduction hand lever is connected with a sample introduction hand lever sliding block, and the sample introduction hand lever sliding block moves along a sample introduction hand lever sliding rail; the sample introduction hand shifting sliding block is connected with a sample introduction hand shifting belt through a sample introduction hand shifting belt connecting piece; the sample injection hand shifting motor drives the sample injection hand shifting driving wheel to rotate, and the sample injection hand shifting driving wheel drives the sample injection hand shifting driven wheel to rotate through the sample injection hand shifting belt.
The sample injection shifting handle belt rotates to drive the sample injection shifting handle to move, and the sample injection shifting handle can shift the sample rack to the moving range of the sampling shifting handle assembly.
Preferably, the sample introduction module further comprises a sample introduction blocking assembly, and a sample introduction blocking piece in the sample introduction blocking assembly is used for blocking the sample rack; a motor shaft of the sample injection blocking motor is sequentially connected with a sample injection blocking baffle and the sample injection blocking piece, one end of the sample injection blocking baffle extends out of the sample injection blocking baffle I, and the other end of the sample injection blocking baffle extends out of the sample injection blocking baffle II; a sample introduction blocking optocoupler I and a sample introduction blocking optocoupler II are respectively arranged above and below the sample introduction blocking piece; when the second sample introduction blocking optocoupler senses that the second sample introduction blocking catch is detected, the sample introduction blocking piece blocks the sample rack; when the sampling blocking optical coupler senses that the sampling blocking separation blade is first, the sampling blocking piece releases the sample rack, so that the sample rack is driven by the sampling and discharging conveying assembly to perform conveying action.
When the sample rack needs to be blocked, the sample introduction blocking piece is controlled to rotate to the sample introduction blocking optocoupler II to sense the sample introduction blocking baffle II, and the movement is stopped, and the sample introduction blocking piece blocks the sample rack to stop the movement; when need not block the sample frame, advance a kind and block reverse motion and advance a kind and block that the opto-coupler sensing advances a kind and block the separation blade and stop the motion promptly, and the sample frame can continue to advance along business turn over appearance conveyer belt.
Preferably, the sample introduction module further comprises a sample outlet blocking assembly, and a sample outlet blocking piece in the sample outlet blocking assembly is used for blocking the sample rack; a motor shaft of the sample outlet blocking motor is sequentially connected with a sample outlet blocking separation blade and the sample outlet blocking piece, one end of the sample outlet blocking separation blade extends out of the first sample outlet blocking separation blade, and the other end of the sample outlet blocking separation blade extends out of the second sample outlet blocking separation blade; a sample outlet blocking optocoupler I and a sample outlet blocking optocoupler II are respectively arranged above and below the sample outlet blocking baffle; when the second sample outlet blocking optocoupler senses the second sample outlet blocking baffle, the sample outlet blocking piece blocks the sample rack; when the sample outlet blocking optical coupler senses that the sample outlet blocking separation blade is one, the sample outlet blocking piece releases the sample rack, so that the sample rack is driven by the sample inlet and outlet conveying assembly to perform conveying action.
When the sample rack is used for sample taking, the sample taking blocking piece blocks and releases the sample rack according to the movement principle of blocking and releasing the sample rack.
Preferably, the sampling shifting handle assembly comprises a sampling shifting handle, the sampling shifting handle comprises a sampling shifting handle I and a sampling shifting handle II, and the sampling shifting handle I and the sampling shifting handle II are respectively connected to two ends of a sampling shifting handle arm; the sampling shifting handle is connected with a sampling shifting handle sliding block, and the sampling shifting handle sliding block moves along a sampling shifting handle sliding rail; the sampling hand-shifting sliding block is connected with a sampling hand-shifting belt through a sampling hand-shifting belt connecting piece, a sampling hand-shifting motor drives a sampling hand-shifting driving wheel to rotate, and the sampling hand-shifting driving wheel drives a sampling hand-shifting belt to rotate from a driving wheel.
The sampling shifting handle belt rotates to drive the sampling shifting handle to move.
Preferably, the sampling hand-dialing belt connecting piece is provided with a sampling hand-dialing blocking piece I and a sampling hand-dialing blocking piece II; the sampling dials hand one and touches the sample frame, promotes the sample frame is to the motion of sampling position, dials hand opto-coupler one sensing when the sampling and dials hand separation blade for one, then sampling dials hand reverse motion, dials two sensing when the sampling and dials hand separation blade for two, then sampling dials two contacts the sample frame continues to stir the sample frame is to former motion direction motion, accomplishes the sample sampling back, sampling dials two and stirs the sample frame gets into the home range that the appearance dialled the hand subassembly.
And the sample rack entering the movable range of the sample outlet shifting hand assembly is shifted into the sample inlet and outlet conveying belt by the sample outlet shifting hand assembly, and then the sampled sample rack is removed.
Preferably, the sample outlet shifting hand assembly is provided with a sample outlet shifting hand, the sample outlet shifting hand is connected with a sample outlet shifting hand sliding block, and the sample outlet shifting hand sliding block moves along a sample outlet shifting hand sliding rail; the sample outlet shifting hand sliding block is connected with a sample outlet shifting hand belt through a sample outlet shifting hand belt connecting piece; the sample outlet shifting handle motor drives the sample outlet shifting handle driving wheel to rotate, and the sample outlet shifting handle driving wheel drives the sample outlet shifting handle to rotate from the driving wheel through the sample outlet shifting handle belt.
The sample outlet shifting handle belt rotates to drive the sample outlet shifting handle to move.
Preferably, the sample introduction module is provided with an emergency detection assembly, the emergency detection assembly comprises an emergency detection position, and the emergency detection position is used for placing a sample; the emergency detection assembly further comprises an emergency detection motor, the emergency detection motor drives the emergency detection screw rod to rotate, and the emergency detection screw rod nut on the emergency detection screw rod is connected with an emergency detection screw rod nut connecting piece; the emergency detection screw-nut connecting piece is connected with the emergency detection position and moves along the emergency detection slide rail through the emergency detection slide block.
When a sample for emergency detection exists, the sample is placed into an emergency detection position, the emergency detection position moves to a sample needle sampling position, and after sampling, the sample for emergency detection is detected by the instrument.
Preferably, the sample needle of the sample filling module quantitatively transfers a sample to be detected into a reaction cup positioned in the reaction and detection module, and the sample needle after transferring the sample is cleaned in a sample needle cleaning station; the sample needle is arranged on a sample needle swing arm, and the sample needle swing arm is connected with a sample needle spline shaft; the sample needle horizontal movement assembly realizes the horizontal rotation movement of the sample needle by driving the sample needle spline shaft to rotate, and the sample needle up-and-down movement assembly realizes the up-and-down movement of the sample needle by driving the sample needle spline shaft to move up and down.
The sample needle can move up and down and horizontally in a rotating mode, and the quantitative moving of the sample needle to the sample to be detected is more automatic.
Preferably, a sample needle protection assembly is arranged on the sample needle swing arm, the sample needle is fixedly connected with the sample needle swing arm through a sample needle seat, a spring bolt of the sample needle protection assembly is fixedly connected to the sample needle seat, and a spring is sleeved on the spring bolt.
The sample needle protection component prevents the sample needle from accidentally touching the bottom to damage the needle head.
Preferably, the top end of the sample needle is connected with a sample needle liquid path interface for connecting a cleaning liquid to clean the inner wall of the sample needle; and a sample needle blocking piece is arranged on a sample needle connecting piece connected with the sample needle seat, and the sample needle blocking piece is matched with a sample needle induction optocoupler on the sample needle swing arm to sense the accidental bottom touching condition of the sample needle and feed a sensing signal back to an instrument CPU, so that the sample needle up-and-down movement assembly is controlled, and the error action of the sample needle up-and-down movement assembly is corrected.
The sample needle separation blade is matched with the sample needle induction optocoupler, the accidental bottom touching condition of the sample needle is induced, and the sample needle up-and-down movement component is timely blocked to continuously drive the sample needle to move downwards to damage the needle head.
Preferably, the sample needle cleaning station comprises a sample needle cleaning liquid inlet, and the sample needle cleaning liquid inlet is communicated with the sample needle cleaning cavity; and a cleaning liquid protection block is arranged on the side surface of the cleaning cavity of the sample needle, and waste liquid after the sample needle is cleaned is discharged through a cleaning liquid discharge port.
The cleaning liquid protection block plays a role in reducing splashing of the cleaning liquid; cleaning liquid enters from a cleaning liquid inlet of the sample needle to wash the outer wall of the sample needle, and waste liquid after cleaning passes through a cleaning liquid outlet; the cleaning in the sample needle is carried out by the cleaning liquid entering the sample needle.
Preferably, the sample needle horizontal movement assembly comprises a sample needle horizontal movement motor, the sample needle horizontal movement motor drives a sample needle horizontal movement driving wheel to rotate, and the sample needle horizontal movement driving wheel drives a sample needle horizontal movement driven wheel to rotate through a sample needle horizontal movement belt; and a sample needle coded disc is arranged below the sample needle horizontal movement driven wheel, the sample needle horizontal movement driven wheel drives the sample needle splined shaft to rotate, and the sample needle coded disc synchronously rotates along with the sample needle.
Preferably, a sample needle limiting groove is formed in the sample needle code disc, and the sample needle limiting groove is matched with the sample needle limiting optocoupler to identify and control the sample needle to be moved, the sample to be released and the cleaning action.
Preferably, the sample needle up-and-down movement assembly comprises a sample needle up-and-down movement motor, the sample needle up-and-down movement motor drives a sample needle up-and-down movement driving wheel to rotate, and the sample needle up-and-down movement driving wheel drives a sample needle up-and-down movement driven wheel to rotate through a sample needle up-and-down movement belt; the sample needle spline shaft is connected with the sample needle up-and-down movement sliding block, and the sample needle up-and-down movement belt drives the sample needle up-and-down movement sliding block to move along the sample needle up-and-down movement sliding rail.
Preferably, the reagent needle of the reagent filling module transfers a reaction reagent into a reaction cup located in the reaction and detection module; the reagent needle is arranged on the reagent needle swing arm, and the reagent needle swing arm is connected with the reagent needle spline shaft; the reagent needle left-right movement assembly realizes the left-right movement of the reagent needle by driving the reagent needle spline shaft to rotate, and the reagent needle up-down movement assembly realizes the up-down movement of the reagent needle by driving the reagent needle spline shaft to move up and down.
The reagent needle can move up and down, left and right, absorbs the reaction reagent, transfers the reaction reagent into the reaction cup in the reaction tray, reacts with the sample, and the reagent needle transfer reaction reagent is more automatic.
Preferably, reagent needle side-to-side motion subassembly is including reagent needle side-to-side motion motor, reagent needle side-to-side motion motor drive reagent needle side-to-side motion action wheel is rotatory, reagent needle side-to-side motion action wheel passes through reagent needle side-to-side motion belt and drives reagent needle side-to-side motion from the driving wheel rotation, via reagent needle side-to-side motion drives from the driving wheel the reagent needle integral key shaft is rotatory.
Preferably, the reagent needle up-and-down movement assembly comprises a reagent needle up-and-down movement motor, the reagent needle up-and-down movement motor drives a reagent needle up-and-down movement driving wheel to rotate, and the reagent needle up-and-down movement driving wheel drives a reagent needle up-and-down movement driven wheel to rotate through a reagent needle up-and-down movement belt; the reagent needle spline shaft is connected with the reagent needle up-and-down movement sliding block, and the reagent needle up-and-down movement belt drives the reagent needle up-and-down movement sliding block to move along the reagent needle up-and-down movement sliding rail through the reagent needle up-and-down movement belt connecting piece.
Preferably, the reagent transferred by the reagent needle is contained in a reagent tray, the reagent tray comprises an inner ring and an outer ring, the outer ring is used for containing the outer ring reagent R1, and the inner ring is used for containing the inner ring reagent R2; reagent is held in the classification of interior outer lane, is difficult for taking place the confusion.
Preferably, the reagent disk is driven to rotate by a reagent disk rotating assembly, the reagent disk rotating assembly comprises a reagent disk rotating motor, the reagent disk rotating motor drives a reagent disk rotating driving wheel to rotate, and the reagent disk rotating driving wheel drives a reagent disk rotating driven wheel to rotate through a reagent disk rotating belt; the reagent disk drives the reagent disk rotating shaft to rotate through the reagent disk rotating driven wheel.
The reagent tray rotates to facilitate the reagent needles to suck the reagents R1 and R2 one by one from the reagent tray containing the reaction reagents, and the reaction reagents are transferred to the reaction tray.
Preferably, the lower part of the reagent disk rotating shaft is connected with a reagent disk coded disk, and a reagent disk limiting groove and a reagent disk limiting sheet are arranged on the reagent disk coded disk; the reagent plate limiting groove is matched with the reagent plate limiting optical coupler I, and the reagent plate limiting sheet is matched with the reagent plate limiting optical coupler II.
The spacing recess of reagent dish and the spacing piece of reagent dish (1 can for discernment number of revolutions) all correspond and set up the opto-coupler, are discerned the number of revolutions of reagent position (every reagent position corresponds a spacing recess) and reagent dish on the reagent dish respectively.
Preferably, a code scanning window is arranged on one side of the reagent disk, and a reagent bottle code scanner scans the reagent bottles at the position of the code scanning window; the device is characterized in that a Peltier and a reagent disk cooling fin are arranged below the reagent disk, and an exhaust fan is arranged on the lower portion of the reagent disk cooling fin.
The reagent bottle code scanner can scan codes of reagent bottles in the reagent tray, and records reagent related information, namely production batch numbers, valid periods, names and the like; the peltier and the reagent disk cooling fins and the two sets of refrigerating components enable the working environment of the peltier to dissipate heat in time, ensure normal refrigerating work of the peltier, and enable the reagent disk to be kept in a low-temperature state so as to enable the reagent to keep reactive activity.
Preferably, the stirring and uniformly mixing module comprises a stirring paddle, and the stirring paddle is driven by a stirring motor to perform stirring action; the stirring paddle is connected with the stirring paddle spline shaft, the stirring paddle left and right movement assembly is driven to rotate the stirring paddle spline shaft to realize the left and right movement of the stirring paddle, the stirring paddle up and down movement assembly is driven to realize the up and down movement of the stirring paddle spline shaft.
And the stirring and uniformly mixing module enables the reaction sample and the reagent in the reaction disc to be stirred and uniformly mixed so as to enable the reaction to be fully carried out.
Preferably, the stirring rake side-to-side movement subassembly is including the stirring rake side-to-side movement motor, the stirring rake side-to-side movement motor drive stirring rake side-to-side movement action wheel is rotatory, the stirring rake side-to-side movement action wheel passes through the stirring rake side-to-side movement belt and drives the stirring rake side-to-side movement from the driving wheel rotation, via the stirring rake side-to-side movement drives from the driving wheel the stirring rake integral key shaft is rotatory.
Preferably, the stirring paddle up-and-down movement assembly comprises a stirring paddle up-and-down movement motor, the stirring paddle up-and-down movement motor drives a stirring paddle up-and-down movement driving wheel to rotate, and the stirring paddle up-and-down movement driving wheel drives a stirring paddle up-and-down movement driven wheel to rotate through a stirring paddle up-and-down movement belt; the stirring paddle spline shaft is connected with the stirring paddle up-and-down movement sliding block, the stirring paddle up-and-down movement belt is driven through the stirring paddle up-and-down movement belt connecting piece, and the stirring paddle up-and-down movement sliding block moves along the stirring paddle up-and-down movement sliding rail.
Preferably, the stirring and uniformly mixing module is also provided with a stirring paddle coded disc, and the stirring paddle coded disc is provided with a stirring paddle coded disc limiting groove; and the stirring paddle coded disc limiting groove is matched with the stirring paddle coded disc limiting optocoupler and is used for identifying the stirring position of the stirring paddle and the cleaning position after stirring.
Preferably, the stirring paddle is connected with the stirring motor through a stirring rod; the stirring and uniformly mixing module is also provided with a stirring paddle cleaning station for cleaning the stirring paddles; the stirring paddle cleaning station comprises a stirring paddle cleaning station inlet, and the stirring paddle cleaning station inlet is communicated with a stirring paddle cleaning liquid inlet through a stirring paddle cleaning cavity; the end surface of the cleaning liquid inlet of the stirring paddle is lower than the end surface of the cleaning station of the stirring paddle, and the splashed liquid flows out through the liquid outlet of the cleaning station of the stirring paddle; the stirring paddle cleaning cavity is communicated with the liquid outlet of the stirring paddle cleaning station through the liquid outlet of the stirring paddle cleaning cavity.
The terminal surface of stirring rake washing liquid entry is lower than the terminal surface of stirring rake cleaning station for when spraying and washing the stirring rake, the liquid that splashes still falls into the stirring rake cleaning station, and flow through the stirring rake cleaning station leakage fluid dram, the washing liquid that does not splash then is discharged by the stirring rake cleaning station leakage fluid dram.
Preferably, the reaction and detection module comprises a reaction disc assembly, the reaction disc assembly is provided with a reaction disc, a plurality of reaction cup positions are arranged in the reaction disc, and the reaction cup positions are used for placing reaction cups; the reaction disc is driven to rotate by the reaction disc moving assembly through the reaction disc rotating shaft, and light signals emitted by the detection light source after passing through the reaction cup are received by the spectrometer box and are detected and analyzed.
The reaction disc rotates, so that the emission light of the detection light source can irradiate the reaction cup which is rotated in place; moreover, the reaction disc is rotated, so that samples and reaction reagents can be added into the reaction cups in the reaction disc in sequence.
Preferably, reaction disc motion subassembly includes reaction disc motion motor, reaction disc motion motor drive reaction disc motion action wheel is rotatory, reaction disc motion action wheel passes through reaction disc motion belt drive reaction disc motion and moves from the driving wheel rotation, via reaction disc motion drives from the driving wheel the rotation of reaction disc pivot.
Preferably, a reaction disc coded disc is arranged in the reaction and detection module, a reaction disc coded disc limiting groove is formed in the reaction disc coded disc corresponding to each reaction cup position, and a first reaction disc coded disc limiting optical coupler is matched with the reaction disc coded disc limiting groove to identify each detection position; the reaction disc coded disc is also provided with a reaction disc coded disc limiting baffle, and the number of rotation turns of the reaction disc is identified through the cooperation of a reaction disc coded disc limiting optical coupler II and the reaction disc coded disc limiting baffle.
Preferably, a heating film is arranged on the bottom surface of each reaction cup position of the reaction disc, and meanwhile, a heat insulation layer is arranged on the reaction disc; a temperature sensor is also arranged below the reaction disc and used for monitoring the temperature; and a flow guide structure is arranged on the side surface of the reaction disc and is used for guiding leaked liquid in the reaction disc.
During reaction, the heating film can be started to incubate the reaction cup at constant temperature according to the requirements of reaction conditions; the guide structure has the function of guiding if leakage exists in the reaction disc, so that the corrosion of the internal structure of the reaction disc is prevented.
Preferably, a heat sink is arranged at the lower part of the detection light source; the spectrometer box is supported by a spectrometer box support, and the detection light source, the heat sink, the spectrometer box and the spectrometer box support constitute a spectrometer box assembly.
The lower part of the detection light source is provided with a radiating fin to ensure that the detection environment temperature is proper.
Preferably, the reaction cup cleaning module comprises a cleaning needle assembly, the cleaning needle assembly is provided with at least one cleaning needle group and a wiping head, and the cleaning needle group comprises a liquid inlet needle and a liquid outlet needle; the cleaning needle assembly is connected with the cleaning needle moving support rod, and the cleaning needle up-and-down moving assembly drives the cleaning needle assembly to move up and down through the cleaning needle moving support rod.
The reaction cup is a non-disposable consumable material which can be repeatedly used after being cleaned, and the reaction cup is cleaned by the up-and-down movement of the cleaning needle; the cleaning needle group cleans the reaction cup, and the wiping head wipes the reaction cup.
Preferably, the cleaning needle up-and-down movement assembly comprises a cleaning needle up-and-down movement motor, the cleaning needle up-and-down movement motor drives a motor shaft connecting rod to rotate, and a connecting rod sliding block is connected to the motor shaft connecting rod; the connecting rod sliding block moves left and right in the sliding groove of the sliding groove block to drive the cleaning needle to move the supporting rod to move up and down; the cleaning needle moving support rod is connected with the sliding groove block, and a cleaning needle moving spring is arranged below the sliding groove block on the cleaning needle moving support rod.
Set up and wash needle motion spring, when preventing that the machine is out of control, wash the needle whereabouts and cause the needle damage.
Preferably, the wiping head is provided with a wiping head groove, and the wiping head groove is clamped with the limiting bolt, so that the wiping head is connected with the wiping head rod; the bottom surface of the wiping head is provided with a groove pipeline.
When the wiping head is pressed down into the reaction cup, residual liquid in the reaction cup enters the groove pipeline, the reaction cup is wiped completely, the next detection is to be used, and the reaction cup can be cleaned and wiped repeatedly before the next detection.
Preferably, the cleaning needle assembly further comprises a cleaning needle assembly bracket, and the cleaning needle assembly is connected below the cleaning needle assembly bracket; a cleaning needle spring seat is arranged on the cleaning needle assembly support, a cleaning needle spring is arranged on the cleaning needle spring seat, and a cleaning needle fixing head is arranged above the cleaning needle spring; the cleaning needle set, the cleaning needle spring seat and the cleaning needle fixing head are assembled to form an integrated cleaning needle set, the integrated cleaning needle set is in non-fixed connection with the cleaning needle assembly support, and the cleaning needle spring is sleeved on the integrated cleaning needle set.
The cleaning needle spring can protect the needle and prevent the needle head from being damaged by falling excessively and accidentally.
Preferably, the reaction cup cleaning module and the stirring and uniformly mixing module are arranged around the reaction and detection module; the sample filling module is arranged on the side surface of the sample introduction module, and the sample filling module and the reagent filling module are both positioned on the side surface of the reaction and detection module; the reaction and detection module is used as a center to carry out reasonable module layout, the coordination time among the modules is fully saved, and the rapid analysis and detection are realized.
Preferably, the full-automatic biochemical analyzer further comprises a sample code scanning device, wherein the sample code scanning device is positioned on the side surface of the sample filling module; the sample code scanning device comprises a sample tube rotating assembly and a code scanning assembly; the sample tube rotating assembly is provided with a rubber ring, and the rubber ring rubs the sample tube to enable the sample tube to rotate; and the code scanner scans the sample tube at different angles to complete the code scanning of the sample tube and record the sample information.
Preferably, the code scanning assembly further comprises a code scanner bracket, and the code scanner is mounted on the code scanner bracket; the sample tube rotating assembly comprises a sample tube rotating motor, the rubber ring is sleeved on a pulley, and the pulley is installed on a motor shaft of the sample tube rotating motor.
The sample code scanning device is arranged on the base, is divided into a sample tube rotating assembly and a code scanning assembly, and is responsible for automatically scanning codes of bar codes on the sample tube and inputting sample information; there is a pulley on the motor shaft, and the rubber circle cover is established on the pulley, and sample tube rotating electrical machines starts, drives the rubber circle and rotates, and rubber circle friction sample tube makes the sample tube rotate, and the sign indicating number ware carries out different angle scanning to the sample tube, accomplishes the sample tube and sweeps the sign indicating number.
Preferably, the sample introduction module is provided with a plurality of sample introduction modules, and two adjacent sample introduction modules are spliced together, so that the sample rack is conveyed to a position farther than the preset sampling position through the plurality of spliced sample introduction modules.
Through the combined splicing of the sample introduction modules, the sample to be detected is more convenient to convey, and the assembling of the instrument is faster; the sampling position can be selected as required, and more detection platforms or instruments can be matched.
Drawings
The following detailed description of embodiments of the invention is made with reference to the accompanying drawings:
FIG. 1 is a schematic view of the overall structure of a fully automatic biochemical analyzer according to the present invention;
FIG. 2 is a schematic top view of the fully automated biochemical analyzer of FIG. 1;
FIG. 3 is a schematic view of the full-automatic biochemical analyzer of FIG. 1 without the sample injection module;
FIG. 4 is a schematic top view of the structure of FIG. 3;
FIG. 5 is a schematic diagram of a sample injection module in the fully automatic biochemical analyzer of FIG. 1;
FIG. 6 is a first schematic view of the sample injection module of FIG. 5 with the emergency detection assembly and the sample circulation support plate removed;
FIG. 7 is a second schematic view of the sample injection module of FIG. 5 with the emergency detection assembly and the sample circulation support plate removed;
FIG. 8 is a schematic view of a sample injection assembly;
FIG. 9 is a schematic view of the sample introduction assembly (with the sample introduction assembly housing removed);
FIG. 10 is a schematic view of the construction of the sampling paddle assembly;
FIG. 11 is a schematic view of the structure of the sample hand-setting assembly;
FIG. 12 is a schematic structural view of a sample blocking assembly;
FIG. 13 is a schematic structural view of the sample withdrawal blocking assembly;
FIG. 14 is a schematic structural view of an emergency detection assembly;
FIG. 15 is a schematic structural view of a sample priming module;
FIG. 16 is a schematic view of the structure of the sample needle swing arm in the sample filling module;
FIG. 17 is a schematic view of the structure of a sample needle in the sample filling module;
FIG. 18 is a schematic top view of a sample needle code wheel of the sample filling module;
FIG. 19 is a schematic cross-sectional view of a sample needle cleaning station in the sample filling module;
FIG. 20 is a perspective view of a sample needle cleaning station in the sample filling module;
FIG. 21 is a schematic diagram of the construction of a reagent fill module (no reagent tray);
FIG. 22 is a schematic view of the overall construction of the reagent fill module;
FIG. 23 is a schematic diagram of a reagent tray assembly in the reagent filling module;
FIG. 24 is a schematic view of the reagent tray cooling assembly in the reagent fill module;
FIG. 25 is a schematic diagram of the reagent disk rotation assembly in the reagent fill module;
FIG. 26 is an enlarged partial schematic view of FIG. 25;
FIG. 27 is a first schematic structural view of a stirring and mixing module;
FIG. 28 is a schematic structural view II of the stirring and kneading module;
FIG. 29 is a schematic view of the structure of the stirring paddle in the stirring and mixing module;
FIG. 30 is a schematic structural view I of a stirring paddle cleaning station in the stirring and mixing module;
FIG. 31 is a schematic structural view of a second stirring paddle cleaning station in the stirring and blending module;
FIG. 32 is a schematic structural view of a third stirring paddle cleaning station in the stirring and mixing module;
FIG. 33 is a first schematic structural view of a reaction and detection module;
FIG. 34 is a schematic view of the structure of a reaction cup in the reaction and detection module;
FIG. 35 is an enlarged partial schematic view of the reaction and detection module of FIG. 33;
FIG. 36 is a schematic structural view II of a reaction and detection module;
FIG. 37 is a schematic sectional view of a reaction disk in the reaction and detection module;
FIG. 38 is a schematic view showing the structure of a reaction disk moving unit in the reaction and detection module;
FIG. 39 is a schematic view of the construction of a spectrometer cartridge assembly in a reaction and detection module;
FIG. 40 is a first schematic view of the structure of the cuvette cleaning module;
FIG. 41 is a schematic structural view II of the cuvette washing module;
FIG. 42 is a partial enlarged view of the cleaning pin set in the cuvette cleaning module;
FIG. 43 is a schematic view of the structure of a wiper head in the cuvette washing module;
FIG. 44 is a schematic view showing the structure of the washing needle assembly in the cuvette washing module;
FIG. 45 is a first schematic view of a sample scanning apparatus;
FIG. 46 is a second schematic structural view of a sample code scanner;
FIG. 47 is a schematic view of a partial enlarged structure of the sample code scanner of FIG. 45;
FIG. 48 is a schematic view of the reaction cup cleaning module performing a cleaning operation;
FIG. 49 is a test flow chart of the fully automatic biochemical analyzer of the present invention;
wherein: 1-sample introduction module, 101-sample holder, 102-sample tube, 103-sample in and out transfer assembly, 10301-sample in and out transfer belt, 10302-sample in and out transfer motor, 10303-sample in and out transfer driving wheel, 10304-sample in and out synchronous wheel one, 10305-sample in and out synchronous wheel two, 10306-sample in and out synchronous wheel three, 104-sampling hand dialing assembly, 10401-sampling hand dialing, 10402-sampling hand dialing one, 10403-sampling hand dialing two, 10404-sampling hand dialing arm, 10405-sampling hand dialing slider, 10406-sampling hand dialing slide rail, 10407-sampling hand dialing belt connector, 10408-sampling hand dialing belt, 10409-sampling hand dialing motor, 104010-sampling hand dialing driving wheel, 104011-sampling hand dialing driven wheel, 104012-sampling hand dialing sheet one, 104013-sampling hand dialing sheet two, 104014-sampling hand optical coupler I, 104015-sampling hand optical coupler II, 105-sample feeding assembly, 10501-sample feeding assembly shell, 106-sample feeding track changing push hand assembly, 10601-sample feeding track changing push hand, 10602-sample feeding track changing push hand sliding block, 10603-sample feeding track changing push hand sliding rail, 10604-sample feeding track changing push hand belt connecting piece, 10605-sample feeding track changing push hand belt, 10606-sample feeding track changing push hand motor, 10607-sample feeding track changing push hand driving wheel, 10608-sample feeding track changing push hand driven wheel, 107-sample feeding hand shifting assembly and 10701-sample feeding hand; 10702-sample introduction hand shifting slider, 10703-sample introduction hand shifting slide rail, 10704-sample introduction hand shifting belt connector, 10705-sample introduction hand shifting belt, 10706-sample introduction hand shifting motor, 10707-sample introduction hand shifting drive wheel, 10708-sample introduction hand shifting driven wheel, 108-sample introduction blocking component, 10801-sample introduction blocking piece, 10802-sample introduction blocking motor, 10803-sample introduction blocking piece, 10804-sample introduction blocking piece I, 10805-sample introduction blocking piece II, 10806-sample introduction blocking optical coupler I, 10807-sample introduction blocking optical coupler II, 109-sample introduction blocking component, 10901-sample introduction blocking piece, 10902-sample introduction blocking motor, 10903-sample introduction blocking piece, 10904-sample introduction blocking piece I, 10905-sample introduction blocking piece II, 10906-sample introduction blocking optical coupler I, 10907-sample introduction blocking optical coupler II, 1010-sample out hand-dialing component, 101001-sample out hand-dialing, 101002-sample out hand-dialing sliding block, 101003-sample out hand-dialing sliding rail, 101004-sample out hand-dialing belt connector, 101005-sample out hand-dialing belt, 101006-sample out hand-dialing motor, 101007-sample out hand-dialing driving wheel, 101008-sample out hand-dialing driven wheel, 1011-emergency detection component, 101101-emergency detection position, 101102-emergency detection motor, 101103-emergency detection screw rod, 101104-emergency detection screw nut, 101105-emergency detection screw nut connector, 101106-emergency detection sliding block, 101107-emergency detection sliding rail and 1012-sample circulation supporting plate; 2-sample filling module, 201-sample needle, 20101-sample needle head, 202-sample needle cleaning station, 20201-sample needle cleaning liquid inlet, 20202-sample needle cleaning cavity, 20203-cleaning liquid guard block, 20204-cleaning liquid discharge port, 203-sample needle swing arm, 204-sample needle spline shaft, 205-sample needle horizontal movement assembly, 20501-sample needle horizontal movement motor, 20502-sample needle horizontal movement driving wheel, 20503-sample needle horizontal movement belt, 20504-sample needle horizontal movement driven wheel, 206-sample needle up-and-down movement assembly, 20601-sample needle up-and-down movement motor, 20602-sample needle up-and-down movement driving wheel, 20603-sample needle up-and-down movement belt, 20604-sample needle up-and-down movement driven wheel, 20605-sample needle up-and-down movement slider, 20606-sample needle up-and-down movement sliding rail, 207-sample needle protection component, 20701-spring bolt, 20702-spring, 208-sample needle seat, 209-sample needle liquid path interface, 2010-sample needle connecting piece, 2011-sample needle baffle, 2012-sample needle induction optical coupler, 2013-sample needle code disc, 201301-sample needle limiting groove and 201302-sample needle limiting optical coupler; 3-reagent filling module, 301-reagent needle, 302-reagent needle swing arm, 303-reagent needle spline shaft, 304-reagent needle left and right movement component, 30401-reagent needle left and right movement motor, 30402-reagent needle left and right movement driving wheel, 30403-reagent needle left and right movement belt, 30404-reagent needle left and right movement driven wheel, 305-reagent needle up and down movement component, 30501-reagent needle up and down movement motor, 30502-reagent needle up and down movement driving wheel, 30503-reagent needle up and down movement belt, 30504-reagent needle up and down movement driven wheel, 30505-reagent needle up and down movement slide block, 30506-reagent needle up and down movement belt connecting piece, 30507-reagent needle up and down movement slide rail, 306-reagent disk, 30601-outer ring, 30602-inner ring, 307-reagent disk rotation component, 30701-reagent disk rotating motor, 30702-reagent disk rotating driving wheel, 30703-reagent disk rotating belt, 30704-reagent disk rotating driven wheel, 30705-reagent disk rotating shaft, 308-reagent disk coded disk, 30801-reagent disk limiting groove, 30802-reagent disk limiting sheet, 30803-reagent disk limiting optical coupler I, 30804-reagent disk limiting optical coupler II, 309-code scanning window, 3010-reagent bottle code scanner, 3011-Peltier, 3012-reagent disk radiating fin and 3013-exhaust fan; 4-stirring and uniformly mixing module, 401-stirring paddle, 402-stirring motor, 403-stirring paddle spline shaft, 404-stirring paddle left and right movement component, 40401-stirring paddle left and right movement motor, 40402-stirring paddle left and right movement driving wheel, 40403-stirring paddle left and right movement belt, 40404-stirring paddle left and right movement driven wheel, 405-stirring paddle up and down movement component, 40501-stirring paddle up and down movement motor, 40502-stirring paddle up and down movement driving wheel, 40503-stirring paddle up and down movement belt, 40504-stirring paddle up and down movement driven wheel, 40505-stirring paddle up and down movement slide block, 40506-stirring paddle up and down movement belt connecting piece, 40507-stirring paddle up and down movement slide rail, 406-stirring paddle, 40601-stirring paddle limit slot, 40602-stirring paddle optical coupling limit code disc, 407-stirring rod, 408-stirring paddle cleaning station, 40801-stirring paddle cleaning station inlet, 40802-stirring paddle cleaning cavity, 40803-stirring paddle cleaning liquid inlet, 40804-stirring paddle cleaning station liquid outlet, 40805-stirring paddle cleaning cavity liquid outlet; 5-reaction and detection module, 501-reaction disc component, 50101-reaction disc, 50102-reaction cup position, 502-reaction disc motion component, 50201-reaction disc motion motor, 50202-reaction disc motion driving wheel, 50203-reaction disc motion belt, 50204-reaction disc motion driven wheel, 503-reaction disc rotating shaft, 504-detection light source, 505-spectrometer box, 506-reaction disc coded disc, 50601-reaction disc coded disc limiting groove, 50602-reaction disc coded disc limiting optical coupler I, 50603-reaction disc coded disc limiting baffle, 50604-reaction disc coded disc limiting optical coupler II, 507-heating film, 508-heat preservation layer, 509-temperature sensor, 5010-flow guide structure, 5012-radiating fin, 5013-spectrometer box bracket and 5014-spectrometer box component; 6-reaction cup cleaning module; 601-cleaning needle assembly, 60101-cleaning needle set, 60102-wiping head, 60103-liquid inlet needle, 60104-liquid discharge needle, 60105-wiping head groove, 60106-limit bolt, 60107-groove pipeline, 60108-cleaning needle assembly support, 60109-cleaning needle spring seat, 601010-cleaning needle spring, 601011-cleaning needle fixing head, 601012-wiping head rod, 602-cleaning needle movement supporting rod, 603-cleaning needle up-and-down movement assembly, 60301-cleaning needle up-and-down movement motor, 60302-motor shaft connecting rod, 60303-connecting rod sliding block, 60304-sliding groove block and 60305-cleaning needle movement spring; 7-a base; 8-reaction cup, 801-reaction cup detection window; 9-a sample code scanning device, 901-a sample tube rotating component, 90101-a rubber ring, 90102-a sample tube rotating motor, 90103-a pulley and 902-a code scanning component; 90201-code scanner, 90202-code scanner support.
Detailed Description
As shown in fig. 1-4, the full-automatic biochemical analyzer of the present embodiment includes a sample injection module 1, a sample injection module 2, a reagent injection module 3, a reaction and detection module 5, a stirring and mixing module 4, and a reaction cup cleaning module 6; the sample filling module 2, the reagent filling module 3, the reaction and detection module 5, the stirring and uniformly mixing module 4 and the reaction cup cleaning module 6 are all arranged on the base 7; the sample injection module 1 conveys a sample to be detected to a preset sampling position, when the full-automatic biochemical analyzer is used for detecting according to the requirement of the sample to be detected, the sample injection module 1 conveys the sample to be detected to the preset sampling position matched with the full-automatic biochemical analyzer, and the sample to be detected is transferred to the reaction and detection module 5 for detection through the sample injection module 2; the reagent filling module 3 is used for filling a reagent into a sample to be detected, the stirring and mixing module 4 is used for stirring and mixing the sample to be detected and the reagent, and the reaction cup cleaning module 6 is used for cleaning the reaction cup 8.
The reaction cup cleaning module 6 and the stirring and uniformly mixing module 4 are arranged around the reaction and detection module 5; the sample filling module 2 is arranged on the side surface of the sample injection module 1, and the sample filling module 2 and the reagent filling module 3 are both positioned on the side surface of the reaction and detection module 5.
The full-automatic biochemical analyzer is provided with an operation screen which is a 10-inch display touch screen and can be externally connected with a keyboard and a mouse; the touch screen can be displayed to carry out operation control and information input on the instrument, and meanwhile, information such as a detection result, a curve and an instrument state can be checked.
The sample introduction module 1 and the base 7 are mutually independent, so that the adaptability of the sample introduction module 1 is enlarged; as shown in fig. 5-14, the sample injection module 1 includes a sample rack 101, at least one sample tube 102 is disposed on the sample rack 101, and 10 sample tubes 102 are disposed on the sample rack 101 of this embodiment, as shown in fig. 5; the sample rack 101 is driven by the sample in and out transfer assembly 103 to perform a transfer operation; the sample introduction module 1 further comprises a sample introduction assembly 105 and a sampling hand dialing assembly 104, wherein the sample introduction assembly 105 performs sample introduction action on the sample holder 101, and the sampling hand dialing assembly 104 performs poking action on the sample holder 101.
As shown in fig. 6 and 7, the sample inlet and outlet transfer assembly 103 includes a sample inlet and outlet transfer belt 10301, and the sample rack 101 is connected to the sample inlet and outlet transfer belt 10301, specifically, when performing biochemical analysis, the sample rack 101 is placed on the sample inlet and outlet transfer belt 10301, and a sample flow support plate 1012 (shown in fig. 5) is disposed on a side surface of the sample inlet and outlet transfer belt 10301, so as to facilitate sample inlet and sample outlet flow of the sample rack 101; the sample inlet and outlet conveying belt 10301 is driven by a sample inlet and outlet conveying motor 10302, the sample inlet and outlet conveying motor 10302 drives a sample inlet and outlet conveying driving wheel 10303 to rotate, and the sample inlet and outlet conveying driving wheel 10303 drives a sample inlet and outlet synchronizing wheel I10304, a sample inlet and outlet synchronizing wheel II 10305 and a sample inlet and outlet synchronizing wheel III 10306 to rotate through the sample inlet and outlet conveying belt 10301.
The sample feeding assembly 105 comprises a sample feeding track-changing pushing hand assembly 106 and a sample feeding hand shifting assembly 107, as shown in fig. 8 and 9, the sample feeding track-changing pushing hand assembly 106 is provided with a sample feeding track-changing pushing hand 10601, and the sample feeding hand shifting assembly 107 is provided with a sample feeding hand shifting hand 10701; the sample injection track-changing push handle 10601 pushes the sample rack 101 on the sample inlet and outlet conveyor belt 10301 into the movable range of the sample injection hand-pusher 10701, and the sample rack 101 is then pushed by the sample injection hand-pusher 10701 into the movable range of the sampling hand-pusher assembly 104.
The sample introduction rail change pusher 10601 is connected to the sample introduction rail change pusher slider 10602, and as shown in fig. 8 and 9, the sample introduction rail change pusher slider 10602 moves along the sample introduction rail change pusher slide 10603; the sample injection track-changing push hand sliding block 10602 is connected with a sample injection track-changing push hand belt 10605 through a sample injection track-changing push hand belt connecting piece 10604; the sample injection rail-changing push hand motor 10606 drives the sample injection rail-changing push hand driving wheel 10607 to rotate, and the sample injection rail-changing push hand driving wheel 10607 drives the sample injection rail-changing push hand driven wheel 10608 to rotate through the sample injection rail-changing push hand belt 10605; it should be noted that the sample injection track-changing pusher motor 10606 is located inside the sample injection assembly housing 10501.
The sample introduction hand setting block 10701 is connected with a sample introduction hand setting slider 10702, and the sample introduction hand setting block 10702 moves along a sample introduction hand setting slide rail 10703; the sample introduction hand shifting slide block 10702 is connected with a sample introduction hand shifting belt 10705 through a sample introduction hand shifting belt connecting piece 10704; the sample injection hand driving wheel 10707 is driven by the sample injection hand driving motor 10706 to rotate, and the sample injection hand driving wheel 10707 drives the sample injection hand driven wheel 10708 to rotate through the sample injection hand driving belt 10705, as shown in fig. 8 and 9.
The sample injection module 1 further includes a sample injection blocking assembly 108, as shown in fig. 12, a sample injection blocking piece 10801 in the sample injection blocking assembly 108 is used for blocking the sample rack 101; a motor shaft of the sample injection blocking motor 10802 is sequentially connected with the sample injection blocking baffle 10803 and the sample injection blocking piece 10801, one end of the sample injection blocking baffle 10803 extends out of the sample injection blocking baffle I10804, and the other end of the sample injection blocking baffle II 10805 extends out of the sample injection blocking baffle II; a sample introduction blocking optical coupler 10806 and a sample introduction blocking optical coupler 10807 are respectively arranged above and below the sample introduction blocking baffle 10803; when the second injection blocking optical coupler 10807 senses the second injection blocking baffle 10805, the sample injection blocking piece 10801 blocks the sample rack 101; when the sample injection blocking optical coupler 10806 senses that the sample injection blocking baffle 10804 is detected, the sample injection blocking piece 10801 lets the sample rack 101 pass through, so that the sample rack 101 is driven by the sample inlet and outlet conveying assembly 103 to perform conveying action.
The sample introduction module 1 further includes a sample exit blocking assembly 109, as shown in fig. 13, a sample exit blocking member 10901 in the sample exit blocking assembly 109 is used for blocking the sample rack 101; a motor shaft of the sample outlet blocking motor 10902 is sequentially connected with the sample outlet blocking baffle 10903 and the sample outlet blocking member 10901, one end of the sample outlet blocking baffle 10903 extends out of the first sample outlet blocking baffle 10904, and the other end of the sample outlet blocking baffle 10903 extends out of the second sample outlet blocking baffle 10905; a first sample outlet blocking optocoupler 10906 and a second sample outlet blocking optocoupler 10907 are respectively arranged above and below the sample outlet blocking baffle 10903; when the second sample outlet blocking optocoupler two 10907 senses that the second sample outlet blocking baffle 10905, the sample outlet blocking piece 10901 blocks the sample rack 101; when the first sample outlet blocking optocoupler one 10906 senses the first sample outlet blocking flap 10904, the first sample outlet blocking piece 10901 releases the sample rack 101, so that the sample rack 101 is driven by the sample inlet and outlet conveying assembly 103 to perform conveying action.
The sampling hand-dialing component 104 includes a sampling hand-dialing member 10401, as shown in fig. 10, the sampling hand-dialing member 10401 is composed of a first sampling hand-dialing member 10402 and a second sampling hand-dialing member 10403, and the first sampling hand-dialing member 10402 and the second sampling hand-dialing member 10403 are respectively connected to two ends of a sampling hand-dialing arm 10404; the sampling hand-shifting block 10401 is connected with the sampling hand-shifting slide block 10405, and the sampling hand-shifting slide block 10405 moves along the sampling hand-shifting slide rail 10406; the sampling hand-dialing slider 10405 is connected with a sampling hand-dialing belt 10408 through a sampling hand-dialing belt connector 10407, the sampling hand-dialing motor 10409 drives the sampling hand-dialing driving wheel 104010 to rotate, and the sampling hand-dialing driving wheel 104010 drives the sampling hand-dialing driven wheel 104011 to rotate through the sampling hand-dialing belt 10408.
The sampling hand-shifting belt connecting piece 10407 is provided with a sampling hand-shifting block sheet I104012 and a sampling hand-shifting block sheet II 104013 in opposite directions; sampling hand-dialing 104012 contact sample frame 101, promote sample frame 101 to the motion of sampling position, when sampling hand-dialing opto-coupler 104014 sensing sampling hand-dialing separation blade 104012, then sampling hand-dialing 10401 reverse motion, when sampling hand-dialing opto-coupler 104015 sensing sampling hand-dialing separation blade two 104013, then sampling hand-dialing two 10403 contact sample frame 101 continues to dial sample frame 101 to former motion direction motion, after accomplishing the sample sampling, sampling hand-dialing two 10403 dials sample frame 101 and gets into the home range who produces appearance hand-dialing subassembly 1010.
The sample output hand-pulling assembly 1010 is provided with a sample output hand-pulling 101001, as shown in fig. 11; the sample outlet shifting hand 101001 is connected with the sample outlet shifting hand sliding block 101002, and the sample outlet shifting hand sliding block 101002 moves along the sample outlet shifting hand sliding rail 101003; the sample outlet shifting hand slider 101002 is connected with a sample outlet shifting hand belt 101005 through a sample outlet shifting hand belt connector 101004; the sample outlet hand shifting motor 101006 drives the sample outlet hand shifting driving wheel 101007 to rotate, and the sample outlet hand shifting driving wheel 101007 drives the sample outlet hand shifting driven wheel 101008 to rotate through the sample outlet hand shifting belt 101005.
The sample introduction module 1 is provided with an emergency detection assembly 1011, as shown in fig. 14, the emergency detection assembly 1011 includes an emergency detection position 101101, and the emergency detection position 101101 is used for placing a sample; the emergency detection assembly 1011 further comprises an emergency detection motor 101102, the emergency detection motor 101102 drives the emergency detection screw rod 101103 to rotate, and an emergency detection screw nut 101104 on the emergency detection screw rod 101103 is connected with an emergency detection screw nut connecting piece 101105; the emergency detection screw-nut connector 101105 is connected with an emergency detection position 101101, and the emergency detection screw-nut connector 101105 moves along the emergency detection slide rail 101107 through the emergency detection slide block 101106.
It should be noted that, in the sample introduction module 1 of the present embodiment, one sample rack 101 can hold 10 samples at a time, support standard cups, microcups, and test tubes, and support barcode scanning, and if a barcode is attached to a test tube, the apparatus will automatically identify the barcode to read information; the sample introduction track (i.e., in the running direction of the sample inlet and outlet conveyor belt 10301) includes 1 emergency detection position 101101, and a sample to be detected can be placed in the emergency detection position 101101 for emergency test.
The length part (sample injection track) of the sample inlet and outlet conveyor belt 10301 on the side surface of the base 7 can be divided into three parts, namely a sample injection region, a sample suction region and a sample outlet region; the sample introduction area is used for storing samples to be tested, the sample suction area is used for sampling the samples, the sample outlet area is used for storing the samples which are tested, the sample introduction area belongs to the moving range of the sample introduction assembly, the sample suction area belongs to the moving range of the sampling shifting handle assembly 104, and the sample outlet area belongs to the moving range of the sample outlet shifting handle assembly 1010.
The sample injection module 1 of this embodiment may also have a plurality of sample injection modules, and two adjacent sample injection modules are spliced together, so that the sample rack 101 is conveyed to a position farther than the sampling position of the full-automatic biochemical analyzer of this embodiment through the plurality of sample injection modules 1 that are spliced.
As shown in fig. 15-20, the sample needle 201 of the sample filling module 2 quantitatively removes the sample to be detected into the reaction cup in the reaction and detection module 5, and the sample needle 201 after removing the sample is cleaned in the sample needle cleaning station 202; the sample needle 201 (the sample needle head 20101 is located at the bottommost part of the sample needle 201 as shown in fig. 17) is mounted on the sample needle swing arm 203, and the sample needle swing arm 203 is connected with the sample needle spline shaft 204; the sample needle horizontal movement assembly 205 realizes the horizontal rotation movement of the sample needle 201 by driving the sample needle spline shaft 204 to rotate, and the sample needle up-down movement assembly 206 realizes the up-down movement of the sample needle 201 by driving the sample needle spline shaft 204 to move up and down.
The sample needle swing arm 203 is provided with a sample needle protection assembly 207, the sample needle 201 is fixedly connected with the sample needle swing arm 203 through a sample needle seat 208, a latch 20701 of the sample needle protection assembly 207 is fixedly connected on the sample needle seat 208, and a spring 20702 is sleeved on the latch 20701.
The top end of the sample needle 201 is connected with a sample needle liquid path interface 209 and is used for connecting a cleaning liquid and cleaning the inner wall of the sample needle 201; a sample needle blocking piece 2011 is arranged on the sample needle connecting piece 2010 connected with the sample needle base 208, the sample needle blocking piece 2011 is matched with a sample needle induction optocoupler 2012 on the sample needle swing arm 203, so that the accidental bottom touching condition of the sample needle 201 is induced, an induction signal is fed back to an instrument CPU, the sample needle up-and-down movement assembly 206 is controlled, and the error action is corrected.
The sample needle cleaning station 202 includes a sample needle cleaning liquid inlet 20201, and the sample needle cleaning liquid inlet 20201 communicates with the sample needle cleaning chamber 20202; the side surface of the sample needle cleaning cavity 20202 is provided with a cleaning solution protection block 20203, and waste liquid after cleaning the sample needle 201 is discharged through a cleaning solution liquid discharge port 20204.
The sample needle horizontal movement assembly 205 comprises a sample needle horizontal movement motor 20501, the sample needle horizontal movement motor 20501 drives the sample needle horizontal movement driving wheel 20502 to rotate, and the sample needle horizontal movement driving wheel 20502 drives the sample needle horizontal movement driven wheel 20504 to rotate through a sample needle horizontal movement belt 20503; a sample needle code disc 2013 is arranged below the sample needle horizontal movement driven wheel 20504, the sample needle horizontal movement driven wheel 20504 drives the sample needle spline shaft 204 to rotate, and the sample needle code disc 2013 synchronously rotates with the sample needle 201.
A sample needle limiting groove 201301 is formed in the sample needle code disc 2013, the sample needle limiting groove 201301 is matched with the sample needle limiting optocoupler 201302, and the sample needle 201 is moved to take a sample to be detected, released and cleaned.
The sample needle up-and-down movement assembly 206 comprises a sample needle up-and-down movement motor 20601, the sample needle up-and-down movement motor 20601 drives the sample needle up-and-down movement driving wheel 20602 to rotate, and the sample needle up-and-down movement driving wheel 20602 drives the sample needle up-and-down movement driven wheel 20604 to rotate through the sample needle up-and-down movement belt 20603; the sample needle spline shaft 204 is connected with the sample needle up-and-down movement slider 20605, and the sample needle up-and-down movement belt 20603 drives the sample needle up-and-down movement slider 20605 to move along the sample needle up-and-down movement slide rail 20606.
The sample needle 201 sucks a set amount of a sample to be detected from the sample container (sample tube 102) and then adds it to the cuvette 8; meanwhile, the sample needle 201 also has the functions of liquid level detection, anti-collision detection and needle blockage detection, which belong to the prior art, and no improvement scheme is made in the invention; during analysis: the sample needle 201 is cyclically swung, lowered, and raised in the order of "sample container → reaction cup → sample needle cleaning pool". The sample needle 201 is cleaned after each sample application. The inner and outer walls of the sample needle 201 are cleaned in the sample needle cleaning station 202.
The reagent needle 301 of the reagent filling module 3 transfers the reaction reagent into the reaction cup positioned in the reaction and detection module 5; as shown in fig. 21 to 26, a reagent needle 301 is mounted on a reagent needle swing arm 302, and the reagent needle swing arm 302 is connected with a reagent needle spline shaft 303; the reagent needle left-right movement assembly 304 realizes the left-right movement of the reagent needle 301 by driving the reagent needle spline shaft 303 to rotate, and the reagent needle up-down movement assembly 305 realizes the up-down movement of the reagent needle 301 by driving the reagent needle spline shaft 303 to move up and down.
The reagent needle left-right movement assembly 304 includes a reagent needle left-right movement motor 30401, the reagent needle left-right movement motor 30401 drives a reagent needle left-right movement driving wheel 30402 to rotate, the reagent needle left-right movement driving wheel 30402 drives a reagent needle left-right movement driven wheel 30404 to rotate through a reagent needle left-right movement belt 30403, and the reagent needle spline shaft 303 is driven to rotate through the reagent needle left-right movement driven wheel 30404.
The reagent needle up-and-down movement assembly 305 comprises a reagent needle up-and-down movement motor 30501, the reagent needle up-and-down movement motor 30501 drives a reagent needle up-and-down movement driving wheel 30502 to rotate, and the reagent needle up-and-down movement driving wheel 30502 drives a reagent needle up-and-down movement driven wheel 30504 to rotate through a reagent needle up-and-down movement belt 30503; the reagent needle spline shaft 303 is connected with a reagent needle up-and-down movement slider 30505, and a reagent needle up-and-down movement belt 30503 drives the reagent needle up-and-down movement slider 30505 to move along a reagent needle up-and-down movement slide rail 30507 through a reagent needle up-and-down movement belt connector 30506.
The reagent transferred by the reagent needle 301 is contained in the reagent tray 306, and the reagent tray 306 includes an inner ring 30602 and an outer ring 30601, wherein the outer ring 30601 contains an outer ring reagent R1, and the inner ring 30602 contains an inner ring reagent R2.
The reagent disk 306 is driven to rotate by the reagent disk rotating assembly 307, the reagent disk rotating assembly 307 comprises a reagent disk rotating motor 30701, the reagent disk rotating motor 30701 drives the reagent disk rotating main driving wheel 30702 to rotate, and the reagent disk rotating main driving wheel 30702 drives the reagent disk rotating driven wheel 30704 to rotate through the reagent disk rotating belt 30703; reagent disk 306 imparts rotational motion to reagent disk rotation shaft 30705 via reagent disk rotation driven wheel 30704.
The lower part of the reagent disk rotating shaft 30705 is connected with a reagent disk coded disk 308, and a reagent disk limiting groove 30801 and a reagent disk limiting sheet 30802 are arranged on the reagent disk coded disk 308; the reagent tray limiting groove 30801 is matched with the reagent tray limiting optical coupler I30803, and the reagent tray limiting sheet 30802 is matched with the reagent tray limiting optical coupler II 30804.
A code scanning window 309 is arranged on one side of the reagent disk 306, and the reagent bottle code scanner 3010 scans the code of the reagent bottle at the position of the code scanning window 309; reagent disk cooling modules (two sets) are arranged below the reagent disk 306, specifically, a peltier 3011 and a reagent disk cooling fin 3012, and a fan 3013 is arranged below the reagent disk cooling fin 3012, as shown in fig. 24.
The reagent tray 306 is used for placing a reagent bottle and sending a reagent and an alkaline cleaning solution to the suction position of the reagent needle 301. The refrigerating system consisting of the peltier 3011, the reagent tray cooling fins 3012 and the exhaust fan 3013 can refrigerate the reagent tray 306, so as to store the reagent conveniently at low temperature; a bar code reader window may also be provided to scan the bar code on the reagent bottle.
The reagent needle 301 sucks a set amount of reagent from the reagent bottle and adds the reagent into the reaction cup 8 in the reaction and detection module 5; the reagent needle 301 is also a liquid level sensor (which belongs to the prior art), and the remaining amount of the reagent is calculated according to the descending distance of the reagent needle 301; when performing biochemical analysis: the reagent needle 301 is sequentially moved cyclically in the order of a reagent bottle, a cuvette, and a reagent needle cleaning station (the same structure as the sample needle cleaning station 202).
The stirring and blending module 4 comprises a stirring paddle 401, as shown in fig. 27-32, the stirring paddle 401 is driven by a stirring motor 402 to perform a stirring action, as shown in fig. 29; the stirring paddle 401 is connected with the stirring paddle spline shaft 403, the stirring paddle left-right movement assembly 404 drives the stirring paddle spline shaft 403 to rotate to realize the left-right movement of the stirring paddle 401, and the stirring paddle up-down movement assembly 405 drives the stirring paddle spline shaft 403 to move up and down to realize the up-down movement of the stirring paddle 401.
The stirring paddle left and right movement component 404 comprises a stirring paddle left and right movement motor 40401, the stirring paddle left and right movement motor 40401 drives the stirring paddle left and right movement driving wheel 40402 to rotate, the stirring paddle left and right movement driving wheel 40402 drives the stirring paddle left and right movement from the driving wheel 40404 to rotate through the stirring paddle left and right movement belt 40403, and the stirring paddle spline shaft 403 is driven to rotate through the stirring paddle left and right movement from the driving wheel 40404.
The stirring paddle up-and-down movement component 405 comprises a stirring paddle up-and-down movement motor 40501, the stirring paddle up-and-down movement motor 40501 drives the stirring paddle up-and-down movement driving wheel 40502 to rotate, and the stirring paddle up-and-down movement driving wheel 40502 drives the stirring paddle up-and-down movement driven wheel 40504 to rotate through a stirring paddle up-and-down movement belt 40503; the spline shaft 403 of the stirring paddle is connected with the up-and-down moving slide block 40505 of the stirring paddle, and the up-and-down moving belt 40503 of the stirring paddle drives the up-and-down moving slide block 40505 of the stirring paddle to move along the up-and-down moving slide rail 40507 of the stirring paddle through the up-and-down moving belt connecting piece 40506 of the stirring paddle.
The stirring and uniformly mixing module 4 is also provided with a stirring paddle coded disc 406, and a stirring paddle coded disc limiting groove 40601 is arranged on the stirring paddle coded disc 406; the stirring paddle coded disc limiting groove 40601 is matched with the stirring paddle coded disc limiting optocoupler 40602 and used for identifying the stirring position of the stirring paddle 401 and the cleaning position of the stirring paddle 401 after stirring.
The stirring paddle 401 is connected with the stirring motor 402 through a stirring rod 407; the stirring and uniformly mixing module 4 is also provided with a stirring paddle cleaning station 408 for cleaning the stirring paddle 401; the paddle cleaning station 408 includes a paddle cleaning station inlet 40801, and the paddle cleaning station inlet 40801 is in communication with a paddle cleaning fluid inlet 40803 through a paddle cleaning chamber 40802; the end face of the paddle cleaning liquid inlet 40803 is lower than the end face of the paddle cleaning station 408, and the splashed liquid flows out through the paddle cleaning station liquid outlet 40804; the paddle wash chamber 40802 is in communication with the paddle wash station drain 40804 through a paddle wash chamber drain 40805.
The stirring paddle 401 stirs the reaction solution (sample and reagent) in the cuvette 8; during biochemical analysis: swinging according to the conditions of 'reaction cup → stirring paddle cleaning station'; descending, stirring rod rotating, ascending and stirring rod stopping rotating are sequentially carried out at two positions; when the stirring paddle 401 is cleaned, the stirring paddle 401 moves to the stirring paddle cleaning station inlet 40801 and moves downwards to the stirring paddle cleaning cavity 40802, cleaning liquid enters from the stirring paddle cleaning liquid inlet 40803 on the side surface of the stirring paddle cleaning station 408, the stirring paddle 401 is sprayed and washed, a stirring paddle cleaning cavity liquid outlet 40805 is arranged in the stirring paddle cleaning cavity 40802, waste liquid flows out from the stirring paddle cleaning cavity liquid outlet 40805, meanwhile, other splashed liquid flows out from the stirring paddle cleaning station liquid outlet 40804, and finally flows out from the stirring paddle cleaning station liquid outlet 40804 and enters a liquid channel drainage system (which belongs to the prior art and is not improved in the invention).
As shown in fig. 33-39, the reaction and detection module 5 includes a reaction disc assembly 501, the reaction disc assembly 501 has a reaction disc 50101, a plurality of reaction cup positions 50102 are arranged in the reaction disc 50101, the reaction cup positions 50102 are used for placing reaction cups 8, the reaction disc 50101 of this embodiment has 81 reaction cups (the testing speed is high, the reaction disc has a plurality of holes, there are 81 reaction cups, the sample is detected by multiple fluxes, the detection efficiency is improved), the reaction cups are fixed on the reaction disc 50101, the reaction solution is reacted in a thermostatic bath at 37 ℃, the absorbance is measured during rotation, and the reaction cups 8 are biochemical reaction carriers; the reaction disk 50101 is driven to rotate by the reaction disk moving assembly 502 through the reaction disk spindle 503, and the optical signal of the emitted light of the detection light source 504 passing through the reaction cup 8 is received by the spectrometer box 505 and is detected and analyzed (the side of the reaction cup 8 has a reaction cup detection window 801, and the spectrometer box 505 detects the liquid after the reaction through the reaction cup detection window 801); when the reaction disk 50101 rotates, absorbance of pure water or the reaction solution in the reaction cup 8 is measured.
The reaction disk motion assembly 502 comprises a reaction disk motion motor 50201, the reaction disk motion motor 50201 drives a reaction disk motion driving wheel 50202 to rotate, the reaction disk motion driving wheel 50202 drives a reaction disk motion driven wheel 50204 to rotate through a reaction disk motion belt 50203, and the reaction disk motion driven wheel 50204 drives a reaction disk rotating shaft 503 to rotate.
A reaction disc coded disc 506 is arranged in the reaction and detection module 5, a reaction disc coded disc limiting groove 50601 is formed in the reaction disc coded disc 506 corresponding to each reaction cup position 50102, and each detection position is identified through cooperation of a reaction disc coded disc limiting optocoupler one 50602 and the reaction disc coded disc limiting groove 50601; reaction disc coded disc 506 is also provided with a reaction disc coded disc limiting blocking piece 50603, and reaction disc coded disc limiting optocouplers 50604 are matched with the reaction disc coded disc limiting blocking piece 50603 to identify the number of rotation turns of the reaction disc 50101.
The bottom surface of each reaction cup position 50102 of the reaction disc 50101 is provided with a heating film 507, and the reaction disc 50101 is also provided with a heat insulation layer 508; a temperature sensor 509 is further arranged below the reaction disc 50101 and used for monitoring the temperature, so that the temperature of the thermostatic bath is kept at 37 ℃; a flow guide structure 5010 is arranged on the side face of the reaction disc 50101 and used for guiding leakage liquid in the reaction disc 50101.
A cooling fin 5012 is arranged at the lower part of the detection light source 504; spectrometer cartridge 505 is supported by spectrometer cartridge support 5013, and test light sources 504, heat sink 5012, spectrometer cartridge 505 and spectrometer cartridge support 5013 comprise spectrometer cartridge assembly 5014.
The reaction cup cleaning module 6 comprises a cleaning needle assembly 601, as shown in fig. 40-44, the cleaning needle assembly 601 has at least one cleaning needle set 60101 and one wiping head 60102, the cleaning needle set 60101 comprises a liquid inlet needle 60102 and a liquid outlet needle 60103; the cleaning needle assembly 601 is connected to a cleaning needle moving rod 602, and the cleaning needle assembly 601 is driven by a cleaning needle up-and-down moving assembly 603 through the cleaning needle moving rod 602 to move up and down.
The cleaning needle up-and-down motion assembly 603 comprises a cleaning needle up-and-down motion motor 60301, the cleaning needle up-and-down motion motor 60301 drives a motor shaft connecting rod 60302 to rotate, and a connecting rod sliding block 60303 is connected to the motor shaft connecting rod 60302; the connecting rod slide block 60303 moves left and right in the slide groove of the slide groove block 60304 to drive the cleaning needle moving support rod 602 to move up and down; the cleaning pin movement strut 602 is connected to the sliding channel block 60304 and the cleaning pin movement strut 602 has a cleaning pin movement spring 60305 below the sliding channel block 60304 as shown in fig. 40 and 41.
The wiping head 60102 is provided with a wiping head groove 60105, the wiping head groove 60105 is clamped with the limiting bolt 60106, and the wiping head 60102 is connected with the wiping head rod 601012; a trough line 60107 is provided on the bottom surface of the wiping head 60102, as shown in fig. 43.
The cleaning needle assembly 601 further comprises a cleaning needle assembly bracket 60108, as shown in fig. 44, a cleaning needle group 60101 is connected below the cleaning needle assembly bracket 60108; a cleaning needle spring seat 60109 is arranged on the cleaning needle assembly support 60108, a cleaning needle spring 601010 is arranged on the cleaning needle spring seat 60109, and a cleaning needle fixing head 601011 is arranged above the cleaning needle spring 601010; a cleaning needle group 60101, a cleaning needle spring seat 60109 and a cleaning needle fixing head 601011 are assembled to form an integrated cleaning needle group, the integrated cleaning needle group is in non-fixed connection with a cleaning needle assembly support 60108, and a cleaning needle spring 601010 is sleeved on the integrated cleaning needle group; the cleaning needle assembly 601 of this embodiment has 3 cleaning needle sets 60101 and 1 wiping head 60102 (transmission manner is a link structure), wherein each cleaning needle set 60101 has a liquid inlet needle 60102 and a liquid outlet needle 60103.
The reaction cup cleaning module 6 realizes the functions of sucking away the reaction liquid after the reaction is finished, cleaning the reaction cup, and adding and sucking away pure water for testing the blank of the cup; in this embodiment, as shown in fig. 48, the cuvette is washed by the washing needle assembly 601, and 8 processes are required for washing (twice for each needle), and thus, one cuvette needs to go through 8 steps to complete washing.
As shown in fig. 45-47, the full-automatic biochemical analyzer of the present embodiment further includes a sample code scanning device 9, and the sample code scanning device 9 is located at the side of the sample filling module 2; the sample code scanning device 9 comprises a sample tube rotating assembly 901 and a code scanning assembly 902; the code scanning assembly 902 comprises a code scanner 90201, the sample tube rotating assembly 901 comprises a rubber ring 90101, and the rubber ring 90101 rubs the sample tube 102 to enable the sample tube 102 to rotate; the code scanner 90201 scans the sample tube 102 at different angles, completes code scanning of the sample tube 102 and records sample information; the code scanning assembly 902 further comprises a code scanner support 90202, and the code scanner 90201 is mounted on the code scanner support 90202; the sample tube rotating assembly 901 comprises a sample tube rotating motor 90102, a rubber ring 90101 is sleeved on a pulley 90103, and the pulley 90103 is installed on a motor shaft of the sample tube rotating motor 90102; the sample code scanning device 9 enables the full-automatic biochemical analyzer of the embodiment to have the automatic rotation code scanning function when the sample tube samples.
After the full-automatic biochemical analyzer is started, resetting (cleaning the reaction cup) is firstly carried out, the light source to be detected is stable, the temperature of the reaction disc is balanced, meanwhile, the reagent needle 301, the sample needle 201 and the stirring paddle 401 are all stopped above respective cleaning stations, and after the first reagent R1 is added into the reagent needle → the sample needle is added into the sample → stirring (if the double reagent project is adopted, the second reagent R2 is added into the reagent needle after stirring → stirring) → absorbance measurement → cleaning the reaction cup → shutdown; 81 reaction cups, 12 seconds per cycle, stop after one rotation. And stopping after clockwise rotating for 1 circle and 20 cup positions within 12 seconds in each period, and finishing the actions of adding the reagent R1, adding the sample to be detected and adding the reagent R2. Rotating 80 cup positions every four periods, and gradually advancing one cup position along the opposite direction of rotation; the single reagent test performs reaction and photometry after S stirring, and the double reagent performs reaction and photometry after R2 stirring; the test flow of the fully automatic biochemical analyzer is shown in FIG. 49.
The foregoing shows and describes the general principles, principal features and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are given by way of illustration of the principles of the present invention, but that various changes and modifications may be made without departing from the spirit and scope of the invention, and such changes and modifications are within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (44)

1. A full-automatic biochemical analyzer is characterized by comprising a sample introduction module, a sample filling module, a reagent filling module, a reaction and detection module, a stirring and mixing module and a reaction cup cleaning module; the sample filling module, the reagent filling module, the reaction and detection module, the stirring and mixing module and the reaction cup cleaning module are all arranged on the base; the sample injection module conveys a sample to be detected to a preset sampling position, and the sample to be detected is moved to the reaction and detection module for detection through the sample filling module; the reagent filling module is used for filling a reagent into a sample to be detected, the stirring and mixing module is used for stirring and mixing the sample to be detected and the reagent, and the reaction cup cleaning module is used for cleaning the reaction cup.
2. The fully automated biochemical analyzer according to claim 1, wherein the sample introduction module is independent from the base, thereby expanding a degree of adaptation of the sample introduction module; the sample introduction module comprises a sample rack, and at least one sample tube is placed on the sample rack; the sample rack is driven by the sample inlet and outlet conveying assembly to carry out conveying action; the sampling module further comprises a sampling component and a sampling shifting handle component, wherein the sampling component is right for sampling the sample rack, and the sampling shifting handle component is right for shifting the sample rack.
3. The fully automated biochemical analyzer according to claim 2, wherein the sample inlet and outlet transfer assembly comprises a sample inlet and outlet transfer belt, and the sample rack is placed on the sample inlet and outlet transfer belt; the sample inlet and outlet conveying belt is driven by a sample inlet and outlet conveying motor, the sample inlet and outlet conveying motor drives a sample inlet and outlet conveying driving wheel to rotate, and the sample inlet and outlet conveying driving wheel drives a sample inlet and outlet synchronizing wheel I, a sample inlet and outlet synchronizing wheel II and a sample inlet and outlet synchronizing wheel III to rotate through the sample inlet and outlet conveying belt.
4. The fully automatic biochemical analyzer according to claim 3, wherein the sample feeding assembly comprises a sample feeding track changing pusher assembly and a sample feeding hand shifting assembly, the sample feeding track changing pusher assembly is provided with a sample feeding track changing pusher, and the sample feeding hand shifting assembly is provided with a sample feeding hand shifting; the sample injection track-changing push handle pushes the sample rack positioned on the sample inlet and outlet conveying belt into the movable range of the sample injection hand stirring component, and then the sample injection hand stirring the sample rack into the movable range of the sampling hand stirring component.
5. The fully automatic biochemical analyzer according to claim 4, wherein the sample-feeding track-changing pusher is connected with a sample-feeding track-changing pusher slider, and the sample-feeding track-changing pusher slider moves along a sample-feeding track-changing pusher slide rail; the sample introduction track transfer push hand sliding block is connected with a sample introduction track transfer push hand belt through a sample introduction track transfer push hand belt connecting piece; the sample introduction track-changing push handle motor drives a sample introduction track-changing push handle driving wheel to rotate, and the sample introduction track-changing push handle driving wheel drives a sample introduction track-changing push handle driven wheel to rotate through the sample introduction track-changing push handle belt.
6. The fully automatic biochemical analyzer according to claim 4, wherein the sample hand-setting block is connected with a sample hand-setting slider, and the sample hand-setting slider moves along a sample hand-setting slide rail; the sample injection hand shifting slide block is connected with a sample injection hand shifting belt through a sample injection hand shifting belt connecting piece; the sample injection hand shifting motor drives the sample injection hand shifting driving wheel to rotate, and the sample injection hand shifting driving wheel drives the sample injection hand shifting driven wheel to rotate through the sample injection hand shifting belt.
7. The fully automatic biochemical analyzer according to claim 2, wherein the sample injection module further comprises a sample injection blocking component, and a sample injection blocking part in the sample injection blocking component is used for blocking the sample rack; a motor shaft of the sample injection blocking motor is sequentially connected with a sample injection blocking baffle and the sample injection blocking piece, one end of the sample injection blocking baffle extends out of the sample injection blocking baffle I, and the other end of the sample injection blocking baffle extends out of the sample injection blocking baffle II; a sample introduction blocking optocoupler I and a sample introduction blocking optocoupler II are respectively arranged above and below the sample introduction blocking piece; when the second sampling blocking optocoupler senses the second sampling blocking baffle, the second sampling blocking piece blocks the sample rack; when advance a kind and block the sensing of opto-coupler and advance a kind and block that the separation blade is one-hour, advance a kind and block that then let pass the sample frame, make the sample frame by the drive of business turn over appearance transport assembly carries out the transmission action.
8. The fully automatic biochemical analyzer according to claim 7, wherein the sample introduction module further comprises a sample exit blocking assembly, and a sample exit blocking member in the sample exit blocking assembly is used for blocking the sample rack; a motor shaft of the sample outlet blocking motor is sequentially connected with a sample outlet blocking separation blade and the sample outlet blocking piece, one end of the sample outlet blocking separation blade extends out of the first sample outlet blocking separation blade, and the other end of the sample outlet blocking separation blade extends out of the second sample outlet blocking separation blade; a sample outlet blocking optical coupler I and a sample outlet blocking optical coupler II are respectively arranged above and below the sample outlet blocking baffle; when the second sample outlet blocking optocoupler senses the second sample outlet blocking baffle, the sample outlet blocking piece blocks the sample rack; when the sample outlet blocking optical coupler senses that the sample outlet blocking baffle is one, the sample outlet blocking piece releases the sample rack, so that the sample rack is driven by the sample outlet conveying assembly to carry out conveying action.
9. The fully automatic biochemical analyzer according to claim 2, wherein the sampling hand-dialing component comprises a sampling hand-dialing component, the sampling hand-dialing component comprises a first sampling hand-dialing component and a second sampling hand-dialing component, and the first sampling hand-dialing component and the second sampling hand-dialing component are respectively connected with two ends of a sampling hand-dialing arm; the sampling shifting handle is connected with the sampling shifting handle sliding block, and the sampling shifting handle sliding block moves along the sampling shifting handle sliding rail; sampling hand dialing block is connected with sampling hand dialing belt through sampling hand dialing belt connecting piece, and sampling hand dialing motor drive sampling hand dialing action wheel rotates, sampling hand dialing action wheel passes through sampling hand dialing belt drives sampling hand dialing from the driving wheel rotation.
10. The fully automatic biochemical analyzer according to claim 9, wherein the sampling hand-pulling belt connecting piece is provided with a first sampling hand-pulling blocking piece and a second sampling hand-pulling blocking piece; the sampling dials hand one and touches sample frame promotes sample frame moves to sampling position, and the sensing of dialling the hand opto-coupler of sampling is to sampling dialling the hand separation blade during, then sampling dialling hand reverse motion, the sensing of dialling the hand opto-coupler of sampling is two during the sampling dialling hand separation blade during two, then sampling dialling two contacts the sample frame continues to stir sample frame is to former direction of motion, accomplishes sample sampling back, sampling dialling two stir the sample frame gets into the home range who produces a kind of dialling the hand subassembly.
11. The fully automatic biochemical analyzer according to claim 10, wherein the sample output paddle assembly has a sample output paddle connected to a sample output paddle slider, the sample output paddle slider moving along a sample output paddle slide rail; the sample outlet shifting hand sliding block is connected with a sample outlet shifting hand belt through a sample outlet shifting hand belt connecting piece; the sample outlet hand shifting motor drives the sample outlet hand shifting driving wheel to rotate, and the sample outlet hand shifting driving wheel drives the sample outlet hand shifting driven wheel to rotate through the sample outlet hand shifting belt.
12. The fully automatic biochemical analyzer according to claim 2, wherein the sample feeding module is provided with an emergency detection assembly, the emergency detection assembly comprises an emergency detection position, and the emergency detection position is used for placing a sample; the emergency detection assembly further comprises an emergency detection motor, the emergency detection motor drives the emergency detection screw rod to rotate, and the emergency detection screw rod nut on the emergency detection screw rod is connected with an emergency detection screw rod nut connecting piece; the emergency detection screw-nut connecting piece is connected with the emergency detection position and moves along the emergency detection slide rail through the emergency detection slide block.
13. The fully automated biochemical analyzer according to claim 1, wherein the sample needle of the sample filling module quantitatively transfers a sample to be detected into a reaction cup located in the reaction and detection module, and the sample needle after transferring the sample is cleaned in a sample needle cleaning station; the sample needle is arranged on a sample needle swing arm, and the sample needle swing arm is connected with a sample needle spline shaft; the sample needle horizontal movement assembly realizes the horizontal rotation movement of the sample needle by driving the sample needle spline shaft to rotate, and the sample needle up-and-down movement assembly realizes the up-and-down movement of the sample needle by driving the sample needle spline shaft to move up and down.
14. The fully automatic biochemical analyzer according to claim 13, wherein a sample needle protection assembly is disposed on the sample needle swing arm, the sample needle is fixedly connected to the sample needle swing arm through a sample needle seat, a spring bolt of the sample needle protection assembly is fixedly connected to the sample needle seat, and a spring is sleeved on the spring bolt.
15. The fully automatic biochemical analyzer according to claim 14, wherein the top end of the sample needle is connected to a sample needle liquid path interface for connecting a cleaning liquid to clean the inner wall of the sample needle; and a sample needle separation blade is arranged on a sample needle connecting piece connected with the sample needle seat, the sample needle separation blade is matched with a sample needle induction optocoupler on the sample needle swing arm, the accidental bottom touching condition of the sample needle is induced, an induction signal is fed back to an instrument CPU, and then the sample needle up-and-down movement assembly is controlled.
16. The fully automated biochemical analyzer according to claim 13, wherein the sample needle cleaning station includes a sample needle cleaning liquid inlet port communicating with a sample needle cleaning chamber; and a cleaning liquid protection block is arranged on the side surface of the sample needle cleaning cavity, and waste liquid after the sample needle is cleaned is discharged through a cleaning liquid discharge port.
17. The fully automatic biochemical analyzer according to claim 13, wherein the sample needle horizontal movement assembly comprises a sample needle horizontal movement motor, the sample needle horizontal movement motor drives a sample needle horizontal movement driving wheel to rotate, and the sample needle horizontal movement driving wheel drives a sample needle horizontal movement driven wheel to rotate through a sample needle horizontal movement belt; a sample needle coded disc is arranged below the sample needle horizontal movement driven wheel, the sample needle horizontal movement driven wheel drives the sample needle splined shaft to rotate, and the sample needle coded disc synchronously rotates along with the sample needle.
18. The fully automatic biochemical analyzer according to claim 17, wherein a sample needle limiting groove is arranged on the sample needle code disc, and the sample needle limiting groove is matched with the sample needle limiting optocoupler, so as to identify and control the sample needle to be moved, released and cleaned.
19. The fully automatic biochemical analyzer according to claim 13, wherein the sample needle up-and-down moving assembly comprises a sample needle up-and-down moving motor, the sample needle up-and-down moving motor drives a sample needle up-and-down moving driving wheel to rotate, and the sample needle up-and-down moving driving wheel drives a sample needle up-and-down moving driven wheel to rotate through a sample needle up-and-down moving belt; the sample needle spline shaft is connected with the sample needle up-and-down movement slider, and the sample needle up-and-down movement belt drives the sample needle up-and-down movement slider to move along the sample needle up-and-down movement slide rail.
20. The fully automated biochemical analyzer according to claim 1, wherein the reagent needle of the reagent filling module transfers the reaction reagent into a reaction cup located in the reaction and detection module; the reagent needle swing arm is connected with the reagent needle spline shaft; the reagent needle left-right movement assembly drives the reagent needle spline shaft to rotate so as to realize the left-right movement of the reagent needle, and the reagent needle up-down movement assembly drives the reagent needle spline shaft to move up and down so as to realize the up-down movement of the reagent needle.
21. The automatic biochemical analyzer according to claim 20, wherein the reagent needle left-right movement assembly comprises a reagent needle left-right movement motor, the reagent needle left-right movement motor drives a reagent needle left-right movement driving wheel to rotate, the reagent needle left-right movement driving wheel drives a reagent needle left-right movement driven wheel to rotate through a reagent needle left-right movement belt, and the reagent needle spline shaft is driven to rotate through the reagent needle left-right movement driven wheel.
22. The automatic biochemical analyzer according to claim 20, wherein the reagent needle up-and-down moving assembly comprises a reagent needle up-and-down moving motor, the reagent needle up-and-down moving motor drives a reagent needle up-and-down moving driving wheel to rotate, and the reagent needle up-and-down moving driving wheel drives a reagent needle up-and-down moving driven wheel to rotate through a reagent needle up-and-down moving belt; the reagent needle spline shaft is connected with the reagent needle up-and-down movement sliding block, and the reagent needle up-and-down movement belt drives the reagent needle up-and-down movement sliding block to move along the reagent needle up-and-down movement sliding rail through the reagent needle up-and-down movement belt connecting piece.
23. The fully automated biochemical analyzer according to claim 20, wherein the reagent transferred by the reagent needle is contained in a reagent tray, the reagent tray comprises an inner ring and an outer ring, the outer ring contains an outer ring reagent R1, and the inner ring contains an inner ring reagent R2.
24. The fully automated biochemical analyzer according to claim 23, wherein the reagent disk is driven to rotate by a reagent disk rotation assembly, the reagent disk rotation assembly comprises a reagent disk rotation motor, the reagent disk rotation motor drives a reagent disk rotation driving wheel to rotate, and the reagent disk rotation driving wheel drives the reagent disk rotation driven wheel to rotate through a reagent disk rotation belt; the reagent disk drives the reagent disk rotating shaft to rotate through the reagent disk rotating driven wheel.
25. The fully automatic biochemical analyzer according to claim 24, wherein a reagent disk code disk is connected to a lower portion of the reagent disk rotating shaft, and a reagent disk limit groove and a reagent disk limit sheet are disposed on the reagent disk code disk; the reagent tray limiting groove is matched with the reagent tray limiting optical coupler I, and the reagent tray limiting sheet is matched with the reagent tray limiting optical coupler II.
26. The fully automatic biochemical analyzer according to claim 23, wherein a code scanning window is provided at one side of the reagent tray, and the reagent bottle code scanner scans the reagent bottles at the position of the code scanning window; the device is characterized in that a Peltier and a reagent disk cooling fin are arranged below the reagent disk, and an exhaust fan is arranged on the lower portion of the reagent disk cooling fin.
27. The full-automatic biochemical analyzer according to claim 1, wherein the stirring and mixing module comprises a stirring paddle, and the stirring paddle is driven by a stirring motor to perform a stirring action; the stirring rake is connected with the stirring rake integral key shaft, and the stirring rake side-to-side motion subassembly is through the drive the stirring rake integral key shaft rotates and realizes the side-to-side motion of stirring rake, the stirring rake up-and-down motion subassembly is through the drive the stirring rake integral key shaft up-and-down motion is realized the up-and-down motion of stirring rake.
28. The automatic biochemical analyzer according to claim 27, wherein the paddle left-right movement assembly comprises a paddle left-right movement motor, the paddle left-right movement motor drives a paddle left-right movement driving wheel to rotate, the paddle left-right movement driving wheel drives a paddle left-right movement driven wheel to rotate through a paddle left-right movement belt, and the paddle spline shaft is driven to rotate through the paddle left-right movement driven wheel.
29. The fully automatic biochemical analyzer according to claim 27, wherein the paddle up-and-down movement assembly comprises a paddle up-and-down movement motor, the paddle up-and-down movement motor drives a paddle up-and-down movement driving wheel to rotate, and the paddle up-and-down movement driving wheel drives the paddle up-and-down movement driven wheel to rotate through a paddle up-and-down movement belt; the stirring paddle spline shaft is connected with the stirring paddle up-and-down movement slider, the stirring paddle up-and-down movement belt drives through the stirring paddle up-and-down movement belt connecting piece the stirring paddle up-and-down movement slider moves along the stirring paddle up-and-down movement slide rail.
30. The full-automatic biochemical analyzer according to claim 29, wherein the paddle mixing module further comprises a paddle code wheel, and the paddle code wheel is provided with a paddle code wheel limit groove; and the stirring paddle coded disc limiting groove is matched with the stirring paddle coded disc limiting optocoupler and is used for identifying the stirring position of the stirring paddle and the cleaning position after stirring.
31. The fully automated biochemical analyzer according to claim 27, wherein the paddle is connected to the stirring motor through a stirring rod; the stirring and uniformly mixing module is also provided with a stirring paddle cleaning station for cleaning the stirring paddles; the stirring paddle cleaning station comprises a stirring paddle cleaning station inlet, and the stirring paddle cleaning station inlet is communicated with a stirring paddle cleaning liquid inlet through a stirring paddle cleaning cavity; the end surface of the cleaning liquid inlet of the stirring paddle is lower than the end surface of the cleaning station of the stirring paddle, and the splashed liquid flows out through the liquid outlet of the cleaning station of the stirring paddle; and the stirring paddle cleaning cavity is communicated with the liquid discharge port of the stirring paddle cleaning station through the liquid discharge port of the stirring paddle cleaning cavity.
32. The fully automated biochemical analyzer according to claim 1, wherein the reaction and detection module comprises a reaction tray assembly having a reaction tray with a plurality of reaction cup positions disposed therein for placing reaction cups; the reaction disc is driven to rotate by the reaction disc moving assembly through a reaction disc rotating shaft, and light signals emitted by the detection light source and passing through the reaction cup are received by the spectrometer box and are detected and analyzed.
33. The fully automated biochemical analyzer according to claim 32, wherein the reaction disc motion assembly comprises a reaction disc motion motor, the reaction disc motion motor drives a reaction disc motion driving wheel to rotate, the reaction disc motion driving wheel drives a reaction disc motion driven wheel to rotate through a reaction disc motion belt, and the reaction disc motion driven wheel drives the reaction disc rotating shaft to rotate.
34. The fully automatic biochemical analyzer according to claim 32, wherein a reaction disk code wheel is disposed in the reaction and detection module, the reaction disk code wheel is provided with a reaction disk code wheel limiting groove corresponding to each reaction cup position, and each detection position is identified by a reaction disk code wheel limiting optical coupler I cooperating with the reaction disk code wheel limiting groove; the reaction disc coded disc is also provided with a reaction disc coded disc limiting blocking piece, and the number of rotation turns of the reaction disc is identified through the cooperation of a second reaction disc coded disc limiting optocoupler and the reaction disc coded disc limiting blocking piece.
35. The fully automatic biochemical analyzer according to claim 32, wherein a heating film is disposed on the bottom surface of each reaction cup of the reaction tray, and the reaction tray is further provided with an insulating layer; a temperature sensor is also arranged below the reaction disc and used for monitoring the temperature; and a flow guide structure is arranged on the side surface of the reaction disc and used for guiding leaked liquid in the reaction disc.
36. The fully automatic biochemical analyzer according to claim 32, wherein a heat sink is disposed at a lower portion of the detection light source; the spectrometer box is supported by the spectrometer box support, detect light source, fin, spectrometer box and spectrometer box support and constitute the spectrometer box subassembly.
37. The fully automatic biochemical analyzer according to claim 1, wherein the cuvette washing module comprises a washing needle assembly having at least one washing needle group and a wiping head, the washing needle group comprising a liquid inlet needle and a liquid discharge needle; the cleaning needle assembly is connected with the cleaning needle moving support rod, and the cleaning needle up-and-down moving assembly drives the cleaning needle assembly to move up and down through the cleaning needle moving support rod.
38. The fully automatic biochemical analyzer according to claim 37, wherein the cleaning needle up-and-down movement assembly comprises a cleaning needle up-and-down movement motor, the cleaning needle up-and-down movement motor drives a motor shaft connecting rod to rotate, and a connecting rod sliding block is connected to the motor shaft connecting rod; the connecting rod sliding block moves left and right in the sliding groove of the sliding groove block to drive the cleaning needle moving support rod to move up and down; the cleaning needle motion supporting rod is connected with the sliding groove block, and a cleaning needle motion spring is arranged below the sliding groove block on the cleaning needle motion supporting rod.
39. The fully automated biochemical analyzer according to claim 37, wherein the wiping head has a wiping head groove, and the wiping head groove is engaged with a limit pin so that the wiping head is connected with the wiping head rod; the bottom surface of the wiping head is provided with a groove pipeline.
40. The fully automated biochemical analyzer according to claim 37, wherein the washing needle assembly further comprises a washing needle assembly holder, and the washing needle assembly is connected below the washing needle assembly holder; a cleaning needle spring seat is arranged on the cleaning needle assembly support, a cleaning needle spring is arranged on the cleaning needle spring seat, and a cleaning needle fixing head is arranged above the cleaning needle spring; the cleaning needle set, the cleaning needle spring seat and the cleaning needle fixing head are assembled to form an integrated cleaning needle set, the integrated cleaning needle set is in non-fixed connection with the cleaning needle assembly support, and the cleaning needle spring is sleeved on the integrated cleaning needle set.
41. The fully automatic biochemical analyzer according to any one of claims 1 to 40, wherein the reaction cup cleaning module and the stirring and mixing module are arranged around the reaction and detection module; the sample filling module is arranged on the side surface of the sample introduction module, and the sample filling module and the reagent filling module are both positioned on the side surface of the reaction and detection module.
42. The fully automated biochemical analyzer according to claim 41, further comprising a sample code scanning device located at a side of the sample filling module; the sample code scanning device comprises a code scanner and a rubber ring, and the rubber ring rubs the sample tube to enable the sample tube to rotate; and the code scanner scans the sample tube at different angles to complete code scanning of the sample tube and input sample information.
43. The fully automated biochemical analyzer according to claim 42, wherein the scanner is mounted on a scanner mount; the rubber ring is sleeved on the pulley, and the pulley is arranged on a motor shaft of the sample code scanning motor.
44. The fully automated biochemical analyzer according to claim 2, wherein the sample injection module is provided in plurality, and two adjacent sample injection modules are spliced together, so that the sample rack is transported to a position farther than the preset sampling position through the plurality of spliced sample injection modules.
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