CN114739991B - Urine dryness chemical routine detection method and detection device - Google Patents

Urine dryness chemical routine detection method and detection device Download PDF

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CN114739991B
CN114739991B CN202210643636.2A CN202210643636A CN114739991B CN 114739991 B CN114739991 B CN 114739991B CN 202210643636 A CN202210643636 A CN 202210643636A CN 114739991 B CN114739991 B CN 114739991B
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urine
parameters
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CN114739991A (en
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马丁卯
张建康
候建伟
赵文生
李航
程京
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Tsinghua University
CapitalBio Corp
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251Colorimeters; Construction thereof
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756Sensor type
    • G01N2021/7759Dipstick; Test strip

Abstract

The invention provides a urine dryness chemical routine detection method and a detection device, comprising the following steps: acquiring color parameters corresponding to each color block on a test strip to be detected, wherein the test strip to be detected is dipped in urine to be detected; processing the color parameters to obtain color parameters in a uniform color space; and obtaining a urine routine detection result according to the color parameters and by combining a pre-established target urine routine color database. The urine dryness chemical routine detection method is simple to operate, and the color parameters are converted into the color parameters to be compared with the characteristic parameters in the pre-established target urine routine color database, so that the urine routine detection result with higher accuracy can be obtained.

Description

Chemical routine detection method and detection device for urine dryness
Technical Field
The invention relates to the technical field of medical treatment, in particular to a urine dryness chemical routine detection method and a detection device.
Background
The urine analysis has positive and important significance for the diagnosis of urinary system diseases and the initial evaluation of the health of people.
At present, the conventional test of urine by using test paper is also called dry chemical method, which is a simple and quick test method; the dry chemical method urine routine analysis mainly comprises a visual method and a photoelectric colorimetric method.
Wherein, the visual inspection method is an analysis method which directly uses a dry chemical test paper of urine to dip the urine and compares the color comparison cards of the test paper to obtain the corresponding conventional result of the urine; its advantages are simple operation and low cost, but the color discrimination ability of human eye is different from person to person, and the color change of test paper is affected by time.
The photoelectric colorimetry is a method of determining the content of a measured substance by using photoelectric conversion elements such as photocells or phototubes as detectors and converting optical signals reflected by a measured color patch into voltage signals by using a plurality of light sources with different wavelengths; the photoelectric colorimetry is more objective than a visual method, but is subjected to calculation by converting the reflection intensity of light into a voltage value, so that the accuracy is easily influenced by the reflectivity of the test paper.
Therefore, how to provide a routine urine dry chemistry detection technology with simple operation and high accuracy is a technical problem to be solved urgently by those skilled in the art.
Disclosure of Invention
In view of the above, in order to solve the above problems, the present invention provides a method and a device for detecting urine dryness in a conventional chemical manner, wherein the technical scheme is as follows:
a routine urine dryness chemical detection method, comprising:
acquiring color parameters corresponding to each color block on a test strip to be detected, wherein the test strip to be detected is dipped in urine to be detected;
processing the color parameters to obtain color parameters under a uniform color space;
and obtaining a urine routine detection result according to the color parameters and by combining a pre-established target urine routine color database.
Preferably, in the conventional urine dryness chemical detection method, the obtaining of the color parameter corresponding to each color block on the test strip to be detected includes:
controlling the test strip to be detected to move, and performing data acquisition from a first color block of the test strip to be detected by matching with a color sensor to obtain a color change curve;
and obtaining the color parameters corresponding to each color block based on the color change curve.
Preferably, in the above conventional urine dry chemistry detection method, the conventional urine dry chemistry detection method further comprises:
acquiring a white balance parameter of the test strip to be detected in a detection environment;
correspondingly, before the processing the color parameters to obtain the color parameters in the uniform color space, the method further includes:
and optimizing the color parameters based on the white balance parameters.
Preferably, in the above conventional urine dry chemistry detection method, the conventional urine dry chemistry detection method further comprises:
obtaining test paper type parameters of the test paper strip to be detected;
correspondingly, the obtaining of the urine routine test result according to the color parameters and by combining with a pre-established target urine routine color database comprises the following steps:
selecting a pre-established target urine conventional color database matched with the test paper type parameters according to the test paper type parameters;
and according to the color parameters, combining a pre-established target urine routine color database matched with the test paper type parameters to obtain a urine routine detection result.
Preferably, in the urine dryness chemical routine detection method, the obtaining of the test paper type parameter of the test paper strip to be detected includes:
acquiring a coded color parameter on a color coded color block on the test strip to be detected;
and obtaining the test paper type parameter according to the encoding color parameter.
Preferably, in the above routine urine dry chemistry detection method, the routine urine dry chemistry detection method further comprises:
and acquiring the self color parameter of the urine to be detected.
A urine dryness chemistry routine test device for implementing the urine dryness chemistry routine test method of any one of the above, the urine dryness chemistry routine test device comprising: the device comprises an object stage assembly, a color acquisition assembly, a transmission assembly and a main control board;
the object stage component is used for bearing a test strip to be detected;
the transmission assembly is used for driving the objective table assembly to move;
the color acquisition component is used for acquiring color parameters corresponding to each color block on the test strip to be detected;
the main control board is used for controlling the working states of the objective table assembly, the transmission assembly and the color acquisition assembly, processing the color parameters to obtain color parameters in a uniform color space, and combining a pre-established target urine conventional color database according to the color parameters to obtain a urine conventional detection result.
Preferably, in the above urine dry chemistry conventional detecting device, the stage assembly comprises:
an objective table main body;
the test paper tray is positioned on the objective table main body;
and the white balance color blocks are positioned on the test paper tray.
Preferably, in the above urine dry chemistry conventional detecting device, the color collecting member comprises: a light source, a color sensor, and a diaphragm;
wherein the light source is used for generating an illumination light source;
the color sensor is used for collecting a color change curve on the test strip to be detected;
the diaphragm is used for controlling the light emitting range of the light source and the light sensing range of the color sensor.
Preferably, in the above urine dry chemistry conventional detecting device, the color collecting assembly further comprises: collecting a circuit board;
the collection circuit board is in communication connection with the main control board and is used for controlling the working states of the light source and the color sensor.
Compared with the prior art, the invention has the following beneficial effects:
the chemical routine detection method for urine dryness provided by the invention comprises the following steps: acquiring color parameters corresponding to each color block on a test strip to be detected, wherein the test strip to be detected is dipped in urine to be detected; processing the color parameters to obtain color parameters in a uniform color space; and obtaining a urine routine detection result according to the color parameters and by combining a pre-established target urine routine color database. The urine dryness chemical routine detection method is simple to operate, and the color parameters are converted into color parameters to be compared with the characteristic parameters in the pre-established target urine routine color database, so that a urine routine detection result with higher accuracy can be obtained.
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In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the embodiments or the prior art descriptions will be briefly described below, it is obvious that the drawings in the following description are only embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the provided drawings without creative efforts.
FIG. 1 is a schematic flow chart of a conventional chemical detection method for urine dryness according to an embodiment of the present invention;
fig. 2 is a schematic structural diagram of a test strip to be detected according to an embodiment of the present invention;
fig. 3 is a schematic diagram of a pillar coordinate structure of a CIEL α b color system according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of a saturation difference provided by an embodiment of the present invention;
FIG. 5 is a schematic diagram of a chromaticity difference according to an embodiment of the present invention;
FIG. 6 is a schematic structural diagram of a conventional urine dryness chemical detection device according to an embodiment of the present invention;
FIG. 7 is a schematic structural diagram of a test strip, a test strip tray, and a white balance color block according to an embodiment of the present invention;
fig. 8 is a schematic structural diagram of a color collecting assembly according to an embodiment of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Based on the contents recorded in the background art, the visual inspection method mainly has the following disadvantages:
the test paper is easily influenced by subjective factors, external environments and physiological factors such as color blindness, color weakness and the like, human eyes sense different colors, and even if the results obtained by different people with the same test paper are different.
Secondly, the detection result cannot be stored, and the reproducibility is not good.
And thirdly, the color of the urine test paper changes along with time, and analysis results are different when the time is observed.
And fourthly, the color of the colorimetric card for reference of the test strip is deviated from the actual color.
Fifthly, the influence of the color of urine on the result cannot be eliminated by visual inspection.
The photoelectric colorimetry utilizes the measured voltage value and the known concentration of the solution to establish a regression equation between voltage and concentration, the concentration of the urine to be detected is calculated by obtaining the voltage value after photoelectric conversion of a reflected light signal of the color-developing test paper on which the urine to be detected with corresponding concentration is dripped under the irradiation of a specific light source, the regression equation is established by a test method before detection, and different test papers and corresponding processors with built-in mathematical regression equations can be replaced to detect different substances.
It mainly has the following disadvantages:
firstly, establishing an accurate regression equation is difficult; firstly, a large number of experimental samples are needed, and the work is complex and large; secondly, the error of sample detection is large, the reaction color of the test strip and urine changes along with time, and the quantity of liquid can influence the reflectivity of light.
Secondly, the discrete circuits are more, and the consistency is poor.
And thirdly, because the color can not be reversely deduced, the device can not correctly recognize when the color of the test paper and the non-detection object is changed, which should not happen.
Based on the above, the invention provides a urine dryness chemical routine detection method and a detection device, which are simple to operate and have high accuracy of detection results.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Referring to fig. 1, fig. 1 is a schematic flow chart of a conventional urine dryness chemical detection method according to an embodiment of the present invention.
The conventional urine dryness chemical detection method comprises the following steps:
s101: and acquiring color parameters corresponding to each color block on the test strip to be detected, wherein the urine to be detected is dipped on the test strip to be detected.
S102: and processing the color parameters to obtain the color parameters in the uniform color space.
S103: and obtaining a urine routine detection result by combining a pre-established target urine routine color database according to the color parameters.
The color parameter is an RGB color parameter, and the color parameter is an L a b parameter of a uniform color space.
In this embodiment, referring to fig. 2, fig. 2 is a schematic structural diagram of a test strip to be detected provided in an embodiment of the present invention, and as shown in fig. 2, the test strip to be detected has a plurality of color blocks arranged at intervals in a first direction, where the first direction is a length extending direction of the test strip to be detected, and after the test strip to be detected is dipped in urine to be detected, the urine to be detected chemically reacts with corresponding color blocks to present corresponding colors.
Specifically, the color parameters corresponding to each color block on the test strip to be detected obtained in this step may be:
controlling the test strip to be detected to move, and performing data acquisition from a first color block of the test strip to be detected by matching with a color sensor to obtain a color change curve; and analyzing and processing based on the color change curve to obtain corresponding color parameters on each color block, wherein the color parameters can be understood as RGB color parameters.
Further, in order to ensure the accuracy of the obtained RGB parameters, a white balance parameter under the test environment of the test strip to be detected may be obtained in this step, and then the obtained color parameters may be optimized based on the white balance parameter to obtain color parameters with higher accuracy, so as to improve the accuracy of the urine routine test result.
Then, normalization processing is performed on the obtained RGB color parameters, which specifically includes:
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secondly, linearization treatment is carried out, which specifically comprises the following steps:
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and substituting the normalized rgb data into a linearization function to obtain linearized color data:
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then, XYZ tristimulus values under the uniform color space CIE were calculated:
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calculate the values of L, a, b of the CIE1976 uniform color space:
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wherein:
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wherein
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The tristimulus values of the reference white balance parameters under a D65 light source are specifically as follows:
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referring to fig. 3, fig. 3 is a schematic diagram of a pillar coordinate structure of a CIEL α a b color system according to an embodiment of the present invention.
The color parameters corresponding to each color block on the test strip to be detected are all converted into a CIEL a b uniform color space. The establishment of the uniform color space can make the calculation of the color difference simpler and clearer, and make the calculation result have better correlation with human vision.
Wherein a in the CIEL a b color system shown in fig. 3 is a red-green coordinate, the positive direction of a is red, and the negative direction of a is green; b is a yellow-blue coordinate, the positive direction of b is yellow, and the negative direction of b is blue; c is the saturation and h is the hue angle.
The difference between colors can be analyzed at multiple angles by using the parameters, and the calculation formula is as follows:
lightness difference:
Figure DEST_PATH_IMAGE019
wherein sp represents a sample; std represents a standard sample.
Referring to fig. 4, fig. 4 is a schematic diagram of a saturation difference according to an embodiment of the present invention;
and (3) saturation difference:
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referring to fig. 5, fig. 5 is a schematic diagram of a chromaticity difference according to an embodiment of the invention;
the chroma difference is as follows:
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color difference:
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total chromatic aberration:
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according to the uniform color space theory, in the embodiment of the invention, the urine routine result can be obtained only by preparing the simulated urine standard substance with the standard concentration according to different indexes of the urine routine, collecting the values of L, a and b of the color block color with different concentrations of each index, delimiting the maximum change range of each index of L, a and b, establishing a urine routine color database, and carrying out color comparison on the measured data and the characteristic color parameters in the urine routine color database.
The final result that the color of the test strip to be detected is influenced by the reflectivity difference of the test strip is judged by analyzing and testing the conventional total color difference, and the lightness and chroma color discrimination effect of the test strip to be detected is better by independently analyzing; meanwhile, the method can continuously improve the detection precision and range by utilizing an exhaustive mode, and can be applied to more color identification fields.
It should be noted that there are many types of test strips to be tested, for example, 8, 10, 11, and 14 test strips, and obviously, the corresponding urine routine color database may also be different based on different types of test strips, so in the embodiment of the present invention, the urine dry chemistry routine test method further includes:
and acquiring the test paper type parameters of the test paper strip to be detected.
Correspondingly, the obtaining of the urine routine test result according to the color parameters and by combining with a pre-established target urine routine color database comprises the following steps:
and selecting a pre-established target urine routine color database matched with the test paper type parameters according to the test paper type parameters.
And according to the color parameters, combining a pre-established target urine routine color database matched with the test paper type parameters to obtain a urine routine detection result.
Optionally, in general, in a plurality of color blocks on the test strip, there is a color block as a color-coding color block of the test strip, so that in the embodiment of the present invention, the obtaining of the test strip type parameter of the test strip to be detected includes:
and acquiring the encoding color parameters of the color encoding color block on the test strip to be detected.
And obtaining the test paper type parameter according to the encoding color parameter.
Based on the test paper type parameters, a target urine routine color database matched with the test paper type parameters can be found, so that the accuracy of urine routine detection is further improved.
Optionally, in an embodiment of the present invention, the method for detecting urine dryness conventionally further includes:
and acquiring the self color parameters of the urine to be detected.
Under the normal condition, the color coding color block does not react with the urine to be detected, so that the self color parameter of the urine to be detected can be obtained by detecting the corresponding color on the color coding color block, and the influence of the self color of the urine to be detected on the final result can be reduced based on the self color parameter of the urine to be detected.
Optionally, based on the foregoing embodiment of the present invention, in another embodiment of the present invention, there is further provided a urine dryness chemical routine detecting device, for implementing the urine dryness chemical routine detecting method described in the foregoing embodiment, with reference to fig. 6, fig. 6 is a schematic structural diagram of a urine dryness chemical routine detecting device provided in an embodiment of the present invention, where the urine dryness chemical routine detecting device includes: objective table subassembly, colour acquisition subassembly, drive assembly and main control board.
The object stage assembly is used for bearing the test strip to be detected.
The transmission assembly is used for driving the objective table assembly to move.
The color acquisition component is used for acquiring color parameters corresponding to each color block on the test strip to be detected.
The main control board is used for controlling the working states of the objective table assembly, the transmission assembly and the color acquisition assembly, processing the color parameters to obtain color parameters in a uniform color space, and combining a pre-established target urine routine color database according to the color parameters to obtain a urine routine detection result.
Wherein, the transmission assembly includes at least: slide rail, slider, gear, rack, step motor, photoelectric switch etc..
The main function of the transmission component is to drive the objective table component to move, and the requirement of the color sensor component on color collection of all color blocks on the test paper is met.
Optionally, referring to fig. 7, fig. 7 is a schematic structural diagram including test paper, a test paper tray, and a white balance color block, provided in an embodiment of the present invention, where the stage assembly includes: an objective table main body; the test paper tray is positioned on the objective table main body; and the white balance color blocks are positioned on the test paper tray.
Optionally, the color collecting assembly includes: a light source, a color sensor, and a diaphragm.
Wherein the light source is used for generating an illumination light source.
The color sensor is used for collecting a color change curve on the test strip to be detected.
The diaphragm is used for controlling the light-emitting range of the light source and the photosensitive range of the color sensor.
Optionally, the color collecting assembly further comprises: and collecting the circuit board.
The collection circuit board is in communication connection with the main control board and is used for controlling the working states of the light source and the color sensor.
In this embodiment, this light source can be for high Color Rendering Index (CRI) white LED as the light source, it is concrete with waiting to detect the test paper strip and put into the test paper tray on the objective table subassembly, click at the display interface of device after beginning, the device at first can get into the countdown link, can send the prompt tone after the timing time out and remind the operator to dip in this test paper strip to detect and wait to detect the urine, drive objective table subassembly motion by drive assembly after the time of predetermineeing (for example 60 s) and put into the storehouse, color sensor begins color data collection this moment, after the objective table puts into the storehouse to the target position, color sensor stops color data collection.
The color sensor transmits the collected color change curve to the main control panel through the collecting circuit board for data processing, and calculates the data position of each color block on the color change curve corresponding to the curve, so as to obtain the color parameters corresponding to each color block.
Specifically, each color block corresponds to a peak of the color variation curve and the peak is relatively smooth, so as long as the position of each peak is calculated, the center position is the center position of the corresponding color block, and the RGB value is the RGB value of the corresponding color block.
The collecting circuit board comprises a light source control circuit and a color collecting circuit, wherein the color collecting circuit is built by a color collecting chip, the color collecting chip can be RGB color sensor chips such as TCS34725 and BH1749, and can also be a true color sensor chip conforming to CIE1931 standard XYZ tristimulus values such as TCS 3430.
Further, referring to fig. 8, fig. 8 is a schematic structural diagram of a principle of a color collecting assembly according to an embodiment of the present invention, a detection range of a color sensor is determined as shown in fig. 8, ɸ 1 is a photosensitive range of the color sensor, an opening diameter of a circular optical window of a ɸ 2 diaphragm, a height d1 between the color sensor and the optical window, and a height d2 between the optical window and a test strip to be detected are as follows:
the detection angle of the color sensor is as follows:
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the diameter detected by the test paper is as follows:
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the light path of the light source can be changed based on the design of the diaphragm, emergent light can be uniformly irradiated on the test strip to be detected, the visual angle of the color sensor can be changed, the detection range of the color sensor is smaller than the area of the color blocks of the test strip, and the interference of color parameters between the adjacent color blocks is avoided.
Further, in the device, as shown in fig. 7, a white balance color block is arranged at the front end of the detachable test paper tray, the object stage enters the bin to obtain a first peak point of a color change curve, namely, color data of the white balance color block, and the point position can be directly obtained as a fixed value.
Furthermore, if the second color block on the test strip to be detected is a color-coding color block, the expected test strip type can be obtained by comparing the color of the second color block while the device detects the color of the test strip to be detected, and in addition, the number of peaks of a color curve can be counted to check whether the calculated test strip type is correct, so that a user does not need to set the test strip type before use.
As can be seen from the above description, in the embodiments of the present invention, the data may be used to reverse the color by using the CIEL a b uniform color space recognition method, so as to determine the wrong color; classifying different types of test strips by using the color coding color blocks to realize the function of automatically identifying the test strip models by the device; the light is uniformly irradiated on the color blocks while the visual angle of the color sensor is limited by arranging the diaphragm; and secondly, the diaphragm is matched with the transmission assembly, so that the acquired color change area is a smooth curve and is used for automatically calculating the position of the color block, the operation is simpler and more convenient, and the test error caused by the fact that the test paper is not placed in place is reduced.
Specifically, color data acquired by the color sensor through integral conversion is much better than the consistency and stability of voltage value data acquired through photoelectric conversion; the color sensor colorimetry is colorimetry aiming at color difference, the chromaticity difference can be compared independently so as to eliminate the influence of the reflectivity of the test paper block on the brightness, and the photoelectric method is to detect the reflected illumination intensity with specific wavelength to colorimetry, so that different user operation methods and environments can influence the test result.
Furthermore, in the embodiment of the invention, the color block can be automatically positioned by utilizing the color change curve, so that the error caused by the arrangement position of the test strip to be detected is avoided, and the operability is improved; and the test strip to be detected is provided with the color coding color block, so that the test strip to be detected can be automatically used for identifying the model of the test strip to be detected, and the operation is simple.
Finally, compared with the voltage value acquired by a photoelectric method, the technical scheme provided by the embodiment of the invention can store the color data into the device for later data analysis, the colorimetric database is more accurate with the increase of the data, the white balance color block is used as a white balance reference object, the consistency of the device can be ensured by a software compensation algorithm, and the final result of routine urine detection can be improved to the maximum extent.
The above detailed description is provided for the conventional chemical detection method and device for urine dryness, and the specific examples are applied herein to explain the principle and the implementation of the present invention, and the description of the above examples is only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present invention.
It should be noted that, in the present specification, the embodiments are all described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments may be referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
It is further noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include or include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (8)

1. A urine dryness chemical routine detection method is characterized by comprising the following steps:
acquiring color parameters corresponding to each color block on a test strip to be detected, wherein the test strip to be detected is dipped in urine to be detected;
processing the color parameters to obtain color parameters in a uniform color space;
according to the color parameters, combining with a pre-established target urine routine color database to obtain a urine routine detection result;
the step of obtaining the urine routine detection result according to the color parameters and by combining a pre-established target urine routine color database comprises the following steps:
calculating lightness difference and chroma difference according to the color parameters;
according to the lightness difference and the chroma difference, combining a pre-established target urine conventional color database to obtain a urine conventional detection result;
the acquiring of the color parameter corresponding to each color block on the test strip to be detected comprises the following steps:
controlling the test strip to be detected to move, and performing data acquisition from a first color block of the test strip to be detected by matching with a color sensor to obtain a color change curve;
obtaining color parameters corresponding to each color block based on the color change curve;
obtaining color parameters corresponding to each color block based on the color change curve comprises the following steps: calculating the position of each peak on the color change curve, and taking the central position of the position of each peak as the central position of the corresponding color block to obtain the color parameter corresponding to each color block;
the conventional urine dryness chemical detection method further comprises the following steps:
acquiring a white balance parameter of the test strip to be detected in a detection environment; the acquiring of the white balance parameter of the test strip to be detected in the detection environment comprises: acquiring white balance parameters of the to-be-detected test paper in a detection environment through a white balance color block on a test paper tray, wherein the white balance color block is positioned at the front end of the test paper tray;
correspondingly, before the processing the color parameters to obtain the color parameters in the uniform color space, the method further includes:
and optimizing the color parameters based on the white balance parameters.
2. The routine urine dry chemistry test method of claim 1, further comprising:
obtaining test paper type parameters of the test paper strip to be detected;
correspondingly, the obtaining of the urine routine test result according to the color parameters and by combining with a pre-established target urine routine color database comprises the following steps:
selecting a pre-established target urine conventional color database matched with the test paper type parameters according to the test paper type parameters;
and according to the color parameters, combining a pre-established target urine routine color database matched with the test paper type parameters to obtain a urine routine detection result.
3. The urine dryness chemical routine detection method according to claim 2, wherein the obtaining of the type parameters of the test strip to be detected comprises:
acquiring a coded color parameter on a color coded color block on the test strip to be detected;
and obtaining the test paper type parameter according to the encoding color parameter.
4. The routine urine dry chemistry test method of claim 1, further comprising:
and acquiring the self color parameters of the urine to be detected.
5. A urine dryness chemical routine test device for realizing the urine dryness chemical routine test method according to any one of claims 1 to 4, comprising: the device comprises an object stage assembly, a color acquisition assembly, a transmission assembly and a main control board;
the object stage component is used for bearing a test strip to be detected;
the transmission assembly is used for driving the objective table assembly to move;
the color acquisition component is used for acquiring color parameters corresponding to each color block on the test strip to be detected;
the main control board is used for controlling the working states of the objective table assembly, the transmission assembly and the color acquisition assembly, processing the color parameters to obtain color parameters in a uniform color space, and combining a pre-established target urine conventional color database according to the color parameters to obtain a urine conventional detection result.
6. The urine dryness chemistry routine detecting device according to claim 5, wherein the stage assembly comprises:
an objective table main body;
the test paper tray is positioned on the object stage main body;
and the white balance color blocks are positioned on the test paper tray.
7. The urine dryness chemistry routine detecting device according to claim 5, wherein the color collecting component comprises: a light source, a color sensor, and a diaphragm;
wherein the light source is used for generating an illumination light source;
the color sensor is used for collecting a color change curve on the test strip to be detected;
the diaphragm is used for controlling the light emitting range of the light source and the light sensing range of the color sensor.
8. The urine dryness chemistry routine detection device of claim 7, wherein the color acquisition component further comprises: collecting a circuit board;
the collection circuit board is in communication connection with the main control board and is used for controlling the working states of the light source and the color sensor.
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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007285988A (en) * 2006-04-20 2007-11-01 Wako Pure Chem Ind Ltd Analyzing device and measuring method
CN206270350U (en) * 2016-12-02 2017-06-20 新绎健康科技有限公司 Urine test paper color collecting device
CN106991679A (en) * 2017-03-16 2017-07-28 四川大学 One kind quantifies recognition methods based on cloud platform urine test paper physical signs
CN107024595A (en) * 2017-05-31 2017-08-08 重庆恭逸科技有限公司 A kind of toilet lid with urine examination function
CN107796806A (en) * 2016-09-05 2018-03-13 柯正浩 Screening test paper and its System and method for of inspection
CN208588676U (en) * 2018-07-02 2019-03-08 湖南爱威医疗科技有限公司 Reagent paper detector
CN109557093A (en) * 2018-12-18 2019-04-02 无锡益诺华科技发展有限公司 A kind of urine detection test paper color measuring algorithm
CN114486895A (en) * 2022-01-21 2022-05-13 长沙协大生物科技有限公司 Method for detecting sample substance concentration based on pushing of urine drying test strip to identification

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007285988A (en) * 2006-04-20 2007-11-01 Wako Pure Chem Ind Ltd Analyzing device and measuring method
CN107796806A (en) * 2016-09-05 2018-03-13 柯正浩 Screening test paper and its System and method for of inspection
CN206270350U (en) * 2016-12-02 2017-06-20 新绎健康科技有限公司 Urine test paper color collecting device
CN106991679A (en) * 2017-03-16 2017-07-28 四川大学 One kind quantifies recognition methods based on cloud platform urine test paper physical signs
CN107024595A (en) * 2017-05-31 2017-08-08 重庆恭逸科技有限公司 A kind of toilet lid with urine examination function
CN208588676U (en) * 2018-07-02 2019-03-08 湖南爱威医疗科技有限公司 Reagent paper detector
CN109557093A (en) * 2018-12-18 2019-04-02 无锡益诺华科技发展有限公司 A kind of urine detection test paper color measuring algorithm
CN114486895A (en) * 2022-01-21 2022-05-13 长沙协大生物科技有限公司 Method for detecting sample substance concentration based on pushing of urine drying test strip to identification

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