CN114720708A - Full-automatic temperature-controllable hollow capsule friability inspection device - Google Patents

Full-automatic temperature-controllable hollow capsule friability inspection device Download PDF

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Publication number
CN114720708A
CN114720708A CN202210320241.9A CN202210320241A CN114720708A CN 114720708 A CN114720708 A CN 114720708A CN 202210320241 A CN202210320241 A CN 202210320241A CN 114720708 A CN114720708 A CN 114720708A
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China
Prior art keywords
weight
test chamber
friability
glass tube
chamber
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CN202210320241.9A
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Chinese (zh)
Inventor
王丹丹
郭文旭
蔡志威
章蔼静
俞辉
陈悦
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ZHEJIANG INSTITUTE FOR FOOD AND DRUG CONTROL
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ZHEJIANG INSTITUTE FOR FOOD AND DRUG CONTROL
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Priority to CN202210320241.9A priority Critical patent/CN114720708A/en
Publication of CN114720708A publication Critical patent/CN114720708A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)

Abstract

A full-automatic temperature-controllable hollow capsule friability inspection device comprises a box body for providing a test environment, wherein a vertical partition plate is arranged in the box body to divide the left and right of the inner cavity of the box body into a test chamber and a control chamber; the edge of an opening at the front side of the test chamber is hinged with a transparent chamber door, the top surface in the test chamber is provided with a temperature sensor, and the upper part of the inner wall at the right side of the test chamber is provided with a heating wire; the bottom of the test chamber is provided with a magnesium nitrate saturated solution unit for controlling humidity, and the test chamber is internally provided with a friability test unit; a control unit is arranged in the control chamber; the friability testing unit comprises a capsule sample turntable, a capsule conveying pipe, a weight blanking pipe, a glass pipe, a containing container and a ceramic partition plate. The invention has simple structure, can control the temperature, is a full-automatic friability inspection device, and replaces manual mechanical tedious and repeated labor.

Description

Full-automatic temperature-controllable hollow capsule friability inspection device
Technical Field
The invention relates to the technical field of capsule production detection, in particular to a full-automatic temperature-controllable device for inspecting friability of hollow capsules.
Background
Capsules are common pharmaceutical dosage forms. As a medicine container, the quality of the hollow capsule directly influences the safety and the effectiveness of the medicine. In order to ensure that the capsules are not broken in the production, transportation and use processes to cause powder leakage and medicament exposure, the quality standards of 5 hollow capsules (including gelatin hollow capsules, enteric gelatin hollow capsules, hydroxypropyl methylcellulose hollow capsules, hydroxypropyl starch hollow capsules and pullulan hollow capsules) of different varieties collected in the four parts of China pharmacopoeia 2020 edition all stipulate the items of friability inspection.
The friability of hollow capsules in the current pharmacopoeia edition is specified under the item of examination of friability: taking 50 granules of the product, placing the granules into a watch glass, placing the watch glass into a dryer filled with a saturated solution of magnesium nitrate, keeping the temperature at 25 +/-1 ℃ for 24 hours, taking out the granules, immediately placing the granules one by one into a glass tube (the inner diameter is 24mm, the length is 200mm) which is vertically arranged on a wood plate (the thickness is 2cm), freely dropping a cylindrical weight (the material is polytetrafluoroethylene, the diameter is 22mm, and the weight is 20g +/-0.1 g) from the opening of the glass tube, and judging whether the capsule is broken or not, if so, not more than 5 granules.
In the actual friability checking operation, it was found that it was difficult to achieve the conditions of standing at 25. + -. 1 ℃ for 24 hours in an environment of room temperature and immediately performing friability checking. In addition, 50 capsules are repeatedly checked, and the tedious labor causes fatigue and boring emotion of testers.
Disclosure of Invention
In order to overcome the problems, the invention provides a full-automatic temperature-controllable friability inspection device for hollow capsules.
The technical scheme adopted by the invention is as follows: a full-automatic temperature-controllable hollow capsule friability inspection device comprises a box body for providing a test environment, wherein a vertical partition plate is arranged in the box body to divide the left and right of the inner cavity of the box body into a test chamber and a control chamber; the edge of an opening at the front side of the test chamber is hinged with a transparent chamber door, the top surface in the test chamber is provided with a temperature sensor, and the upper part of the inner wall at the right side of the test chamber is provided with a heating wire; the bottom of the test chamber is provided with a magnesium nitrate saturated solution unit for controlling humidity, and the test chamber is internally provided with a friability test unit; a control unit is arranged in the control chamber;
the friability testing unit comprises a capsule sample turntable, a capsule conveying pipe, a weight blanking pipe, a glass pipe, a containing container and a ceramic partition plate; the capsule sample turntable comprises an upper turntable and a lower fixing disk which are horizontally and coaxially arranged, a rotating shaft is arranged in the center of the upper turntable, and the end part of the rotating shaft is connected with a turntable driving motor; a supporting rod is connected between the rear side of the lower fixed disk and the inner wall of the rear side of the test chamber, and the upper rotary disk rotates relative to the lower fixed disk under the drive of a rotary disk drive motor; the upper fixing disc is provided with a plurality of sample holes which penetrate through the upper fixing disc in the radial direction at intervals along the circumferential direction, and the lower fixing disc is provided with a blanking hole at a position corresponding to the sample holes;
a vertical glass tube is arranged at the lower right side of the blanking hole, the glass tube is communicated up and down, a horizontally arranged wood plate is arranged at the bottom of the glass tube, the wood plate covers the lower opening of the glass tube, and a container is arranged below the wood plate; the blanking hole is connected with the left side of the upper end of the glass tube through the capsule conveying tube; a horizontally arranged conveyor belt is arranged on the right side of the upper end of the glass tube, the right end of the conveyor belt is connected with the weight platform, and the conveying direction of the conveyor belt is from right to left; a vertically arranged weight blanking pipe is arranged above the weight platform and is vertically communicated; a plurality of weights are stacked in the weight blanking pipe, and the distance between the weight blanking pipe and the weight platform is matched with the height of the weights; the weight in the weight blanking pipe sequentially falls to a weight platform, a first pressure sensor is arranged on the weight platform and positioned at the bottom of the weight, a push block is arranged on the right side of the weight, the right end of the push block is connected with an output shaft of a linear cylinder, and the linear cylinder is fixedly arranged on the inner wall of the right side of the test chamber; the linear cylinder drives the push block to move left and right, so that the weights falling onto the weight platform are pushed onto the conveying belt and then fall into the glass tube through the conveying belt;
a second pressure sensor is arranged on the wood plate and positioned in the glass tube, and the right end of the wood plate is connected with an output shaft of the rotary cylinder; the rotary cylinder is fixedly arranged on the inner wall of the right side of the test chamber; the rotary cylinder drives the wood plate to turn over so as to drop the tested capsules and weights in the glass tube to a container; the container is placed on a ceramic partition plate, the ceramic partition plate is arranged above the magnesium nitrate saturated solution unit and is fixedly connected with the inner wall of the test chamber, and a plurality of through holes which are arranged in a matrix form are formed in the ceramic partition plate;
the control unit comprises a controller and a control panel, and the control panel is arranged on the front side surface of the control room; the rotary table driving motor, the temperature sensor, the heating wire, the first pressure sensor, the linear air cylinder, the second pressure sensor and the rotary air cylinder are electrically connected with the controller, the controller controls the rotary table driving motor to operate, the first pressure sensor transmits acquired pressure signals on the weight platform to the controller, the second pressure sensor transmits acquired pressure signals on the wood plate to the controller, and the controller controls the linear air cylinder and the rotary air cylinder to operate according to the acquired pressure signals; the temperature sensor transmits the acquired temperature signal to the controller, and the controller controls the power of the heating wire according to the acquired temperature signal; the controller is electrically connected with the control panel, and the control panel is used for receiving control instructions of an operator.
Furthermore, the box body is of a cuboid structure, and the box door is a glass door.
Furthermore, the aperture of the through hole on the ceramic separator is 0.5-1.0 cm.
Further, the height of the sample hole is 8-12mm, and the diameter of the sample hole is 9-10 mm; the diameter of the blanking hole is 10-11mm, and the diameter of the capsule conveying pipe is the same as the diameter of the blanking hole.
Furthermore, the pipe diameter of the weight blanking pipe is 22-26mm, and the top of the weight blanking pipe penetrates through the top surface of the box body and is fixedly connected with the top surface of the box body.
The invention has the beneficial effects that:
(1) the method can achieve the following requirements specified by the friability check of the empty capsules under the condition of room temperature: conditions for 24 hours at 25. + -. 1 ℃ and immediate friability checking.
(2) The full-automatic test can repeatedly check 50 capsules, and the fatigue and the boring emotion of testers are reduced.
(3) The device has simple structure, can control environmental parameters and can observe real-time conditions through the transparent box door.
Drawings
FIG. 1 is a schematic diagram of the present invention.
Fig. 2 is a schematic view of the internal structure of the present invention.
Fig. 3 is a perspective assembly view of the friability testing unit and heating wire.
Fig. 4 is a schematic view of another embodiment of the present invention.
Description of reference numerals: 1. a box body; 2. a box door; 3. a handle; 4. a control panel; 5. heating wires; 6. a temperature sensor; 7. a turntable driving motor; 8. a rotary cylinder; 9. a linear cylinder; 10. a capsule sample carousel; 11. a capsule delivery tube; 12. a support bar; 13. a conveyor belt; 14. a glass tube; 15. a push block; 16. a wood board; 17. a container; 18. a magnesium nitrate saturated solution unit; 19. a ceramic separator; 20. a weight blanking pipe; 21. a second pressure sensor; 22. a first pressure sensor.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are only some embodiments, but not all embodiments, of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, it should be noted that the orientations or positional relationships indicated as the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., appear based on the orientations or positional relationships shown in the drawings only for the convenience of describing the present invention and simplifying the description, but not for indicating or implying that the referred devices or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" as appearing herein are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present invention, it should be noted that, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" should be interpreted broadly, e.g., as being fixed or detachable or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to the attached drawings, the full-automatic temperature-controllable hollow capsule friability inspection device comprises a box body 1 for providing a test environment, wherein a vertical partition plate is arranged in the box body to divide the left and right inner cavities of the box body 1 into a test chamber and a control chamber; a transparent box door 2 is hinged to the edge of an opening in the front side of the test chamber, a temperature sensor 6 is arranged on the top surface in the test chamber, a heating wire 5 is arranged on the upper portion of the inner wall on the right side of the test chamber, a magnesium nitrate saturated solution unit 18 for controlling humidity is arranged at the bottom of the test chamber, and a friability test unit is arranged in the test chamber; a control unit is arranged in the control chamber;
the friability testing unit comprises a capsule sample turntable 10, a capsule conveying pipe 11, a weight blanking pipe 20, a glass pipe 14, a containing container 17 and a ceramic partition plate 19; the capsule sample turntable 10 comprises an upper turntable and a lower fixing disk which are horizontally and coaxially arranged, a rotating shaft is arranged in the center of the upper turntable, and the end part of the rotating shaft is connected with a turntable driving motor 7; a support rod 12 is connected between the rear side of the lower fixed disk and the inner wall of the rear side of the test chamber, and the upper rotary disk rotates relative to the lower fixed disk under the drive of a rotary disk drive motor 7; the upper fixing disc is provided with a plurality of sample holes which penetrate through the upper fixing disc in the radial direction at intervals along the circumferential direction, and the lower fixing disc is provided with a blanking hole at a position corresponding to the sample holes;
a vertical glass tube 14 is arranged on the lower right side of the blanking hole, the glass tube 14 is communicated up and down, a horizontally arranged wood plate 16 is arranged at the bottom of the glass tube 14, the wood plate 16 shields the lower opening of the glass tube 14, and a container 17 is arranged below the wood plate; the blanking hole is connected with the left side of the upper end of the glass tube 14 through the capsule conveying tube 11; a horizontally arranged conveyor belt 13 is arranged on the right side of the upper end of the glass tube 14, the right end of the conveyor belt 13 is connected with a weight platform, and the conveying direction of the conveyor belt 3 is from right to left; a weight blanking pipe 20 which is vertically arranged is arranged above the weight platform, and the weight blanking pipe 20 is vertically communicated; a plurality of weights are stacked in the weight blanking pipe 20, and the distance between the weight blanking pipe and the weight platform is matched with the height of the weights; the weights in the weight blanking pipe sequentially fall to a weight platform, a first pressure sensor is arranged on the weight platform and positioned at the bottom of the weights, a push block is arranged on the right side of the weights, the right end of the push block is connected with an output shaft of a linear cylinder 9, and the linear cylinder 9 is fixedly arranged on the inner wall of the right side of the test chamber; the linear cylinder 9 drives the push block to move left and right, so that the weights falling onto the weight platform are pushed onto the conveying belt and then fall into the glass tube 14 through the conveying belt;
a second pressure sensor is arranged on the wood plate 16 and positioned in the glass tube, and the right end of the wood plate 16 is connected with an output shaft of the rotary cylinder 8; the rotary cylinder 8 is fixedly arranged on the right inner wall of the test chamber; the rotary cylinder drives the wood plate 16 to turn over so as to drop the tested capsules and weights in the glass tube 14 to the container 17; the container 17 is placed on a ceramic partition plate 19, the ceramic partition plate is arranged above the magnesium nitrate saturated solution unit 18 and is fixedly connected with the inner wall of the test chamber, and a plurality of through holes which are arranged in a matrix form are formed in the ceramic partition plate; the magnesium nitrate saturated solution unit 18 includes a magnesium nitrate saturated solution for controlling humidity in the test chamber.
The control unit comprises a controller and a control panel 4, and the control panel 4 is arranged on the front side surface of the control room;
the temperature sensor 6 and the heating wire 5 are respectively and electrically connected with the controller, the temperature sensor 6 transmits temperature information in the box body to the controller, the controller controls the heating wire 5 to heat according to the temperature information, and the temperature in the box body is set at 25 +/-1 ℃ for 24 hours;
the turntable driving motor 7 is electrically connected with the controller, and after the box body is kept warm at 25 +/-1 ℃ for 24 hours, the controller controls the turntable driving motor 7 to operate for a certain angle so that a sample hole of the upper turntable is superposed with a blanking hole on the lower fixed disk;
the second pressure sensor is electrically connected with the controller, the second pressure sensor transmits a pressure signal on the wood board to the controller, and the controller judges whether the capsule and the weight fall to the wood board according to the pressure signal on the wood board;
the first pressure sensor is electrically connected with the controller, transmits a pressure signal on the weight platform to the controller, and controls to judge whether weights exist on the weight platform according to the pressure signal on the weight platform;
the linear cylinder 9 is electrically connected with the controller, and when the controller judges that the capsule falls to the wood board and a weight exists on the weight platform, the linear cylinder 9 is controlled to do linear reciprocating motion for one time;
the rotary cylinder 8 is electrically connected with the controller, and when the controller judges that the capsule and the weight both fall to the wood board, the rotary cylinder 8 is controlled to do one-time rotary motion;
the control panel is electrically connected with the controller, the control panel is used for receiving instructions of an operator, and the controller is electrically connected with the power supply.
In some embodiments of the present invention, the box body 1 is a rectangular parallelepiped structure, the box door 2 is a glass door, and the box door 2 is provided with a handle 3 for easy opening. The aperture of the through hole on the ceramic separator is 0.5-1.0 cm. The height of the sample hole is 8-14mm, and the diameter of the sample hole is 9-10 mm; the diameter of the blanking hole is 10-11mm, the diameter of the capsule conveying pipe is the same as the aperture of the blanking port, the diameter of the weight blanking pipe is 22-26mm, a plurality of polytetrafluoroethylene weights can be contained at most, and the top of the weight blanking pipe penetrates through the top surface of the box body and is fixedly connected with the top surface of the box body.
In other embodiments of the invention, the control unit further comprises an upper computer, the control panel is a touch display screen, the controller is connected with the upper computer, the upper computer software is operated through the touch display screen, the temperature of the environment box can be set and monitored, the temperature control duration can be set, the alarm reminding function for the temperature exceeding range and the duration expiration can be provided, and the on-off button of the friability testing unit is arranged.
The specific working principle is as follows:
(1) placing a capsule sample in a sample hole of a capsule sample turntable, placing a weight in a weight blanking pipe, starting the device, and placing the capsule sample in a testing chamber at 25 +/-1 ℃ for 24 hours;
(2) the turntable driving motor drives the upper turntable, and when the sample hole of the upper turntable is superposed with the blanking hole of the lower fixed disk, the turntable driving motor stops running; the capsule sample enters the capsule conveying pipe through the blanking hole and then vertically falls into the bottom of the glass pipe, and the second pressure sensor acquires a first pressure signal to indicate that the capsule sample falls into the glass pipe;
(3) the first pressure sensor acquires a pressure signal, which indicates that a weight exists on the weight platform; at the moment, the output shaft of the linear cylinder moves leftwards, and the weight is pushed into the conveying belt; the weight falls to the glass tube through the conveyor belt, and when the weight falls to the bottom of the glass tube, the second pressure sensor acquires a second pressure signal to indicate that the first test is finished;
(4) the output shaft of the rotary cylinder rotates to drive the wood plate to turn over, and the tested capsules and weights enter the container along the same direction.
The embodiments described in this specification are merely illustrative of implementations of the inventive concept and the scope of the present invention should not be considered limited to the specific forms set forth in the embodiments but rather by the equivalents thereof as may occur to those skilled in the art upon consideration of the present inventive concept.

Claims (5)

1. The utility model provides a full-automatic controllable temperature hollow capsule friability inspection device which characterized in that: the testing device comprises a box body for providing a testing environment, wherein a vertical partition plate is arranged in the box body to divide the left and right of an inner cavity of the box body into a testing chamber and a control chamber; the edge of an opening at the front side of the test chamber is hinged with a transparent chamber door, the top surface in the test chamber is provided with a temperature sensor, and the upper part of the inner wall at the right side of the test chamber is provided with a heating wire; the bottom of the test chamber is provided with a magnesium nitrate saturated solution for controlling humidity, and the test chamber is internally provided with a friability test unit; a control unit is arranged in the control chamber;
the friability testing unit comprises a capsule sample turntable, a capsule conveying pipe, a weight blanking pipe, a glass pipe, a containing container and a ceramic partition plate; the capsule sample turntable comprises an upper turntable and a lower fixing disk which are horizontally and coaxially arranged, a rotating shaft is arranged in the center of the upper turntable, and the end part of the rotating shaft is connected with a turntable driving motor; a supporting rod is connected between the rear side of the lower fixed disk and the inner wall of the rear side of the test chamber, and the upper rotary disk rotates relative to the lower fixed disk under the drive of a rotary disk drive motor; the upper fixing disc is provided with a plurality of sample holes which penetrate through the upper fixing disc in the radial direction at intervals along the circumferential direction, and the lower fixing disc is provided with a blanking hole at a position corresponding to the sample holes;
a vertical glass tube is arranged at the lower right side of the blanking hole, the glass tube is communicated up and down, a horizontally arranged wood plate is arranged at the bottom of the glass tube, the wood plate covers the lower opening of the glass tube, and a container is arranged below the wood plate; the blanking hole is connected with the left side of the upper end of the glass tube through the capsule conveying tube; a horizontally arranged conveyor belt is arranged on the right side of the upper end of the glass tube, the right end of the conveyor belt is connected with the weight platform, and the conveying direction of the conveyor belt is from right to left; a weight blanking pipe which is vertically arranged is arranged above the weight platform and is vertically communicated; a plurality of weights are stacked in the weight blanking pipe, and the distance between the weight blanking pipe and the weight platform is matched with the height of the weights; the weight in the weight blanking pipe sequentially falls to a weight platform, a first pressure sensor is arranged on the weight platform and positioned at the bottom of the weight, a push block is arranged on the right side of the weight, the right end of the push block is connected with an output shaft of a linear cylinder, and the linear cylinder is fixedly arranged on the inner wall of the right side of the test chamber; the linear cylinder drives the push block to move left and right, so that the weights falling onto the weight platform are pushed onto the conveying belt and then fall into the glass tube through the conveying belt;
a second pressure sensor is arranged on the wood plate and positioned in the glass tube, and the right end of the wood plate is connected with an output shaft of the rotary cylinder; the rotary cylinder is fixedly arranged on the inner wall of the right side of the test chamber; the rotary cylinder drives the wood plate to turn over so as to drop the tested capsules and weights in the glass tube to a container; the container is placed on a ceramic partition plate, the ceramic partition plate is arranged above the magnesium nitrate saturated solution and is fixedly connected with the inner wall of the test chamber, and a plurality of through holes which are arranged in a matrix manner are formed in the ceramic partition plate;
the control unit comprises a controller and a control panel, and the control panel is arranged on the front side surface of the control room; the rotary table driving motor, the temperature sensor, the heating wire, the first pressure sensor, the linear air cylinder, the second pressure sensor and the rotary air cylinder are electrically connected with the controller, the controller controls the rotary table driving motor to operate, the first pressure sensor transmits acquired pressure signals on the weight platform to the controller, the second pressure sensor transmits acquired pressure signals on the wood board to the controller, and the controller controls the operation of the linear air cylinder and the rotary air cylinder according to the acquired pressure signals; the temperature sensor transmits the acquired temperature signal to the controller, and the controller controls the power of the heating wire according to the acquired temperature signal; the controller is electrically connected with the control panel, and the control panel is used for receiving control instructions of an operator.
2. The apparatus for inspecting friability of fully automatic temperature-controllable hollow capsules according to claim 1, wherein: the box is of a cuboid structure, and the box door is a glass door.
3. The apparatus for inspecting friability of fully automatic temperature-controllable hollow capsules according to claim 1, wherein: the aperture of the through hole on the ceramic separator is 0.5-1.0 cm.
4. The apparatus for inspecting friability of fully automatic temperature-controllable hollow capsules according to claim 1, wherein: the height of the sample hole is 8-12mm, and the diameter of the sample hole is 9-10 mm; the diameter of the blanking hole is 10-11mm, and the diameter of the capsule conveying pipe is the same as the diameter of the blanking hole.
5. The apparatus for inspecting friability of fully automatic temperature-controllable hollow capsules according to claim 1, wherein: the pipe diameter of the weight blanking pipe is 22-26mm, and the top of the weight blanking pipe penetrates through the top surface of the box body and is fixedly connected with the top surface of the box body.
CN202210320241.9A 2022-03-29 2022-03-29 Full-automatic temperature-controllable hollow capsule friability inspection device Pending CN114720708A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210320241.9A CN114720708A (en) 2022-03-29 2022-03-29 Full-automatic temperature-controllable hollow capsule friability inspection device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210320241.9A CN114720708A (en) 2022-03-29 2022-03-29 Full-automatic temperature-controllable hollow capsule friability inspection device

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Publication Number Publication Date
CN114720708A true CN114720708A (en) 2022-07-08

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116671634A (en) * 2023-07-06 2023-09-01 电子科技大学 Balsam pear powder capsule with health care effect and preparation method thereof
CN117890616A (en) * 2024-03-14 2024-04-16 佳木斯大学 Sample batch pretreatment equipment for capsule medicine quality inspection
CN117890616B (en) * 2024-03-14 2024-06-04 佳木斯大学 Sample batch pretreatment equipment for capsule medicine quality inspection

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116671634A (en) * 2023-07-06 2023-09-01 电子科技大学 Balsam pear powder capsule with health care effect and preparation method thereof
CN117890616A (en) * 2024-03-14 2024-04-16 佳木斯大学 Sample batch pretreatment equipment for capsule medicine quality inspection
CN117890616B (en) * 2024-03-14 2024-06-04 佳木斯大学 Sample batch pretreatment equipment for capsule medicine quality inspection

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