CN114712504A - 炎性病况的预防和治疗 - Google Patents
炎性病况的预防和治疗 Download PDFInfo
- Publication number
- CN114712504A CN114712504A CN202210179079.3A CN202210179079A CN114712504A CN 114712504 A CN114712504 A CN 114712504A CN 202210179079 A CN202210179079 A CN 202210179079A CN 114712504 A CN114712504 A CN 114712504A
- Authority
- CN
- China
- Prior art keywords
- cells
- nkt
- type
- tcrαβ
- miltefosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
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- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
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- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462089690P | 2014-12-09 | 2014-12-09 | |
| US62/089,690 | 2014-12-09 | ||
| CN201580075764.XA CN107206086B (zh) | 2014-12-09 | 2015-12-04 | 炎性病况的预防和治疗 |
| PCT/US2015/063930 WO2016094226A1 (en) | 2014-12-09 | 2015-12-04 | Prevention and treatment of inflammatory conditions |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580075764.XA Division CN107206086B (zh) | 2014-12-09 | 2015-12-04 | 炎性病况的预防和治疗 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114712504A true CN114712504A (zh) | 2022-07-08 |
Family
ID=55182541
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210179079.3A Pending CN114712504A (zh) | 2014-12-09 | 2015-12-04 | 炎性病况的预防和治疗 |
| CN201580075764.XA Active CN107206086B (zh) | 2014-12-09 | 2015-12-04 | 炎性病况的预防和治疗 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580075764.XA Active CN107206086B (zh) | 2014-12-09 | 2015-12-04 | 炎性病况的预防和治疗 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20160158258A1 (https=) |
| EP (1) | EP3229811B1 (https=) |
| JP (3) | JP2017537984A (https=) |
| KR (1) | KR102665487B1 (https=) |
| CN (2) | CN114712504A (https=) |
| AU (1) | AU2015360945B2 (https=) |
| BR (1) | BR112017012134A2 (https=) |
| CA (1) | CA3007970A1 (https=) |
| DK (1) | DK3229811T3 (https=) |
| ES (1) | ES2860823T3 (https=) |
| IL (1) | IL252779B (https=) |
| MX (1) | MX381284B (https=) |
| RU (1) | RU2749132C2 (https=) |
| TW (1) | TWI701032B (https=) |
| WO (1) | WO2016094226A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012272642B2 (en) | 2011-06-24 | 2017-09-07 | Gri Bio, Inc. | Prevention and treatment of inflammatory conditions |
| WO2019190986A1 (en) * | 2018-03-26 | 2019-10-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | 3-o-sulfo-galactosylceramide analogs as activators of type ii nkt cells and uses thereof |
| EP4301374A4 (en) | 2021-03-01 | 2025-09-10 | Deciduous Therapeutics Inc | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005299148A1 (en) * | 2004-10-29 | 2006-05-04 | Thomas Haehner | Treatment of the consequences of alcohol abuse hepatitis pancreatitis |
| WO2007149382A2 (en) * | 2006-06-19 | 2007-12-27 | The Cleveland Clinic Foundation | Therapeutic compositions and methods useful in treating hepatitis |
| CN101355929A (zh) * | 2005-12-23 | 2009-01-28 | 哈多技术有限公司 | 治疗和预防变应性疾病的方式和方法 |
| CN103732231A (zh) * | 2011-06-24 | 2014-04-16 | 格里柯瑞歌免疫治疗公司 | 炎性病症的预防和治疗 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE59777B1 (en) * | 1985-12-04 | 1994-04-06 | Max Planck Gesellschaft | Medicaments |
| US6025388A (en) | 1995-04-26 | 2000-02-15 | Allergan Sales, Inc. | Method for inhibiting gene expression promoted by AP1 protein with RARβ selective retinoids and method for treatment of diseases and conditions with such retinoids |
| US5965606A (en) | 1995-12-29 | 1999-10-12 | Allergan Sales, Inc. | Methods of treatment with compounds having RAR.sub.α receptor specific or selective activity |
| US7390795B2 (en) * | 2000-12-18 | 2008-06-24 | Pentraxin Therapeutics Limited | Treatment and prevention of tissue damage |
| US20030133922A1 (en) * | 2002-01-15 | 2003-07-17 | Kasha John R. | Oral tolerance using allogeneic platelets in ITP |
| US20110118197A1 (en) | 2005-09-29 | 2011-05-19 | Vipin Kumar Chaturvedi | Prevention of hepatic ischemic reperfusion injury by administration of sulfatides |
| DE602006019759D1 (de) | 2005-09-29 | 2011-03-03 | Torrey Pines Inst | Sulfatide zur behandlung von autoimmunkrankheiten |
| US8828998B2 (en) * | 2012-06-25 | 2014-09-09 | Infinity Pharmaceuticals, Inc. | Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors |
| WO2014166941A1 (en) * | 2013-04-08 | 2014-10-16 | Academisch Medisch Centrum | Miltefosin or perifosin for use in the treatment of ibd |
-
2015
- 2015-12-04 ES ES15826215T patent/ES2860823T3/es active Active
- 2015-12-04 RU RU2017123761A patent/RU2749132C2/ru active
- 2015-12-04 DK DK15826215.4T patent/DK3229811T3/da active
- 2015-12-04 JP JP2017550464A patent/JP2017537984A/ja active Pending
- 2015-12-04 CN CN202210179079.3A patent/CN114712504A/zh active Pending
- 2015-12-04 TW TW104140844A patent/TWI701032B/zh active
- 2015-12-04 MX MX2017007492A patent/MX381284B/es unknown
- 2015-12-04 CN CN201580075764.XA patent/CN107206086B/zh active Active
- 2015-12-04 BR BR112017012134-4A patent/BR112017012134A2/pt not_active Application Discontinuation
- 2015-12-04 EP EP15826215.4A patent/EP3229811B1/en active Active
- 2015-12-04 CA CA3007970A patent/CA3007970A1/en active Pending
- 2015-12-04 KR KR1020177018579A patent/KR102665487B1/ko active Active
- 2015-12-04 AU AU2015360945A patent/AU2015360945B2/en active Active
- 2015-12-04 WO PCT/US2015/063930 patent/WO2016094226A1/en not_active Ceased
- 2015-12-09 US US14/964,317 patent/US20160158258A1/en active Pending
-
2017
- 2017-06-08 IL IL252779A patent/IL252779B/en not_active IP Right Cessation
-
2021
- 2021-01-04 JP JP2021000288A patent/JP2021059594A/ja active Pending
-
2023
- 2023-01-05 JP JP2023000750A patent/JP7573056B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005299148A1 (en) * | 2004-10-29 | 2006-05-04 | Thomas Haehner | Treatment of the consequences of alcohol abuse hepatitis pancreatitis |
| US20090036400A1 (en) * | 2004-10-29 | 2009-02-05 | Thomas Haehner | Pharmaceutical Preparations for Treating the Consequences of Alcohol Abuse, Hepatitis, Pancreatitis, Alzheimer's Disease, Parkinson's Disease, Diabetes, Toxic Kidney Disease, Reperfusion Damage, Arteriosclerosis, and as an Antidote Against Environmental Toxins and Medicinal Intoxication |
| CN101355929A (zh) * | 2005-12-23 | 2009-01-28 | 哈多技术有限公司 | 治疗和预防变应性疾病的方式和方法 |
| WO2007149382A2 (en) * | 2006-06-19 | 2007-12-27 | The Cleveland Clinic Foundation | Therapeutic compositions and methods useful in treating hepatitis |
| CN103732231A (zh) * | 2011-06-24 | 2014-04-16 | 格里柯瑞歌免疫治疗公司 | 炎性病症的预防和治疗 |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1243961A1 (zh) | 2018-07-27 |
| DK3229811T3 (da) | 2021-03-08 |
| CN107206086B (zh) | 2022-03-18 |
| AU2015360945B2 (en) | 2021-07-29 |
| JP7573056B2 (ja) | 2024-10-24 |
| EP3229811A1 (en) | 2017-10-18 |
| US20160158258A1 (en) | 2016-06-09 |
| KR20170101930A (ko) | 2017-09-06 |
| CN107206086A (zh) | 2017-09-26 |
| KR102665487B1 (ko) | 2024-05-10 |
| RU2017123761A (ru) | 2019-01-10 |
| TWI701032B (zh) | 2020-08-11 |
| WO2016094226A1 (en) | 2016-06-16 |
| JP2021059594A (ja) | 2021-04-15 |
| EP3229811B1 (en) | 2021-02-24 |
| AU2015360945A1 (en) | 2017-07-20 |
| BR112017012134A2 (pt) | 2018-01-23 |
| JP2017537984A (ja) | 2017-12-21 |
| IL252779B (en) | 2020-07-30 |
| TW201639567A (zh) | 2016-11-16 |
| MX381284B (es) | 2025-03-12 |
| CA3007970A1 (en) | 2016-06-16 |
| JP2023030210A (ja) | 2023-03-07 |
| RU2017123761A3 (https=) | 2019-07-17 |
| ES2860823T3 (es) | 2021-10-05 |
| RU2749132C2 (ru) | 2021-06-04 |
| MX2017007492A (es) | 2018-05-04 |
| IL252779A0 (en) | 2017-08-31 |
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