CN114712088B

CN114712088B - Carboxymethyl cellulose wound dressing

Info

Publication number: CN114712088B
Application number: CN202210347301.6A
Authority: CN
Inventors: 陈连节; 黄小培
Original assignee: Zhejiang Longteng Medical New Material Co ltd
Current assignee: Zhejiang Longteng Medical New Material Co ltd
Priority date: 2022-04-01
Filing date: 2022-04-01
Publication date: 2023-05-16
Anticipated expiration: 2042-04-01
Also published as: CN114712088A

Abstract

The invention provides a carboxymethyl cellulose wound dressing, which comprises a dressing body, wherein the dressing body at least comprises a release layer, a wound contact layer, an adhesive layer and a base material; the release layer is overlapped on the outer side of the adhesive layer in a crossing way and extends to cover the outer side of the wound contact layer, so that the anti-pollution effect is realized; the inner side of the wound contact layer is bonded to the inner side of the substrate by the adhesive layer. The wound contact layer comprises a hydrophilic layer and a hydrophobic layer, the hydrophilic layer being located on the outside of the wound contact layer, the hydrophobic layer being located on the inside of the wound contact layer; the hydrophobic layer is bonded to the outside of the adhesive layer. Through the interlude of hydrophilic layer fibre and hydrophobic layer fibre, after hydrophilic layer imbibition produced gel, hydrophobic layer is because capillary phenomenon absorbs the gel that hydrophilic layer formed, and hydrophilic layer combines with hydrophobic layer and forms one layer formula structure, makes hydrophilic layer imbibition also be difficult for droing of production gel, increase of service life.

Description

Carboxymethyl cellulose wound dressing

Technical Field

The invention belongs to the field of wound dressing, and in particular relates to a carboxymethyl cellulose wound dressing.

Background

In wound care, the wound surface is placed in a closed and moist environment, which is beneficial to the accelerated healing of the wound surface. The wound dressing comprises a powder dressing, a gel dressing, a hydrocolloid dressing, a fiber dressing and the like, wherein the most applied hydrocolloid dressing has the basic component of carboxymethyl cellulose, has the characteristic of absorbing wound liquid to form gel, can play a role in keeping proper temperature and humidity of a wound surface, supporting the wound surface and accelerating the healing of the wound surface. The carboxymethyl cellulose can absorb water into the fiber when being contacted with water as a dressing, can be well maintained under pressure, and can be conveniently applied to and removed from a wound; the liquid medicine is directly and vertically absorbed on the dressing, and can not spread along the fabric to wet the skin around the wound. The carboxymethyl cellulose has the characteristic of forming colloid after moisture absorption, has very high moisture absorption and moisture retention, is nontoxic and degradable, and has good biocompatibility.

The patent number CN201210566478.1 is named as 'high-strength and high-hydroscopicity medical dressing containing carboxymethyl cellulose and a preparation method thereof', and the medical dressing is provided, and the carboxymethyl cellulose is made into various absorption materials and further made into medical dressing, so that the medical dressing has the characteristics of high strength, high liquid absorption and the like.

The wound dressing commonly used in the market consists of a release layer, a wound contact layer, a substrate layer and an adhesive. The release layer has the functions of protecting dressing and protecting adhesive, and when the adhesive is used, the release layer is removed from the adhesive, and the adhesive has certain viscosity and can play a role in fixation; the wound contact layer directly contacts the wound surface when in use, and plays roles in protecting and absorbing exudates; the base material has a certain fixing effect.

If carboxymethyl cellulose fiber is directly attached to the adhesive, when the adhesive is used, after the carboxymethyl cellulose fiber absorbs exudates, the carboxymethyl cellulose fiber and water in the exudates form gel, so that the risk that the wound contact layer falls off from the adhesive is easily generated, and the use is influenced.

Disclosure of Invention

In order to solve the problems in the prior art, the invention provides the carboxymethyl cellulose wound dressing, hydrophobic fibers are used as transition materials, after the carboxymethyl cellulose fibers and water are gelled, the gel can be absorbed by capillary phenomenon of the hydrophobic fibers, so that the risk that the carboxymethyl cellulose fibers fall off from an adhesive is avoided, and the service life is prolonged.

In order to solve the technical problems, the invention adopts the following technical scheme:

a carboxymethyl cellulose wound dressing, which comprises a dressing body, wherein the dressing body at least comprises a release layer, a wound contact layer, an adhesive layer and a base material;

the release layer, the wound contact layer, the adhesive layer and the base material are sequentially laminated;

the release layer is 2 pages, is overlapped and covered on the outer side of the adhesive layer in a crossing way and extends and covers the outer side of the wound contact layer, and has an anti-pollution effect; the inner side of the wound contact layer is bonded to the inner side of the substrate by the adhesive layer.

Preferably, the wound contact layer, the adhesive layer and the substrate are compounded by a needle punching hot-pressing process.

Preferably, the release layer is any one of paper, PE, PET, OPP, PC, PS, PMMA, BOPP, a single silicon release film and a teflon release film.

Preferably, the wound contact layer comprises a hydrophilic layer and a hydrophobic layer, the hydrophilic layer being located on the outside of the wound contact layer and the hydrophobic layer being located on the inside of the wound contact layer; the hydrophobic layer is bonded to the outside of the adhesive layer.

Preferably, the hydrophilic layer and the hydrophobic layer are fibrous, and the complexing mode is that the hydrophilic layer fibers and the hydrophobic layer fibers are mutually penetrated, so that gel generated after the hydrophilic layer absorbs liquid is not easy to fall off, and the service life is prolonged.

When the hydrophilic layer absorbs liquid to generate gel, the hydrophobic layer absorbs the gel formed by the hydrophilic layer due to capillary phenomenon, and the hydrophilic layer and the hydrophobic layer are combined to form a layer structure.

Preferably, the hydrophilic layer fiber is carboxymethyl cellulose fiber, and has strong liquid absorption capability.

Preferably, the hydrophobic layer fiber is one or more of terylene, chinlon, spandex, polypropylene, polyvinyl chloride and acrylic.

Preferably, the adhesive layer is one or more of white latex, butyl rubber, epoxy rubber, polyurethane rubber, acrylic ester rubber and polyvinyl acetate rubber, so that the hydrophobic layer is tightly connected with the base material, and simultaneously is adhered to the skin to play a role in fixing the dressing.

Preferably, the substrate is a nonwoven fabric or a polyurethane film.

By adopting the technical scheme, the invention has the following technical effects:

1. according to the carboxymethyl cellulose wound dressing prepared by the invention, hydrophobic fibers are used as transition materials, so that the carboxymethyl cellulose fibers have strong liquid absorption property, and are easy to fall off from an adhesive layer after being formed into gel with water; the gel can be absorbed by the capillary phenomenon of the hydrophobic fiber, so that the risk that the carboxymethyl cellulose fiber falls off from the adhesive is avoided, and the service life is prolonged.

2. The hydrophilic layer fiber adopts carboxymethyl cellulose fiber, so that the liquid absorption capability is strong.

3. The adhesive layer is one or more of white latex, butyl rubber, epoxy rubber, polyurethane rubber, acrylic ester rubber and polyvinyl acetate rubber, so that the hydrophobic layer is tightly connected with the base material, and simultaneously is adhered to the skin to play a role in fixing the dressing.

4. The complexing mode of the hydrophilic layer fiber and the hydrophobic layer fiber is that the hydrophilic layer fiber and the hydrophobic layer fiber are mutually inserted, after the hydrophilic layer absorbs liquid to generate gel, the hydrophobic layer absorbs the gel formed by the hydrophilic layer due to capillary phenomenon, and the hydrophilic layer and the hydrophobic layer are combined to form a layer structure, so that the stability is stronger.

Drawings

FIG. 1 is a schematic view of the structure of a wound dressing of the present invention;

fig. 2 is a cross-sectional view of the construction of a wound dressing of the invention.

The meaning of each reference numeral in the figures is: 1. a release layer; 2. a hydrophilic layer; 3. a hydrophobic layer; 4. an adhesive layer; 5. a substrate.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present invention, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

Referring to fig. 1-2, the present invention is further described by the following embodiments:

EXAMPLE 1 carboxymethyl cellulose wound dressing

A carboxymethyl cellulose wound dressing, which comprises a dressing body, wherein the dressing body at least comprises a release layer 1, a wound contact layer, an adhesive layer 4 and a base material 5; the release layer 1, the wound contact layer, the adhesive layer 4 and the base material 5 are sequentially laminated; the release layer 1 is 2 pages, is overlapped and covered on the outer side of the adhesive layer 4 in a crossing way and extends and covers the outer side of the wound contact layer, and has an anti-pollution effect; the inner side of the wound contact layer is bonded to the inner side of the substrate 5 by the adhesive layer 4.

The wound contact layer, the adhesive layer 4 and the base material 5 are compounded by adopting a needle punching hot-pressing process.

The wound contact layer comprises a hydrophilic layer 2 and a hydrophobic layer 3, the hydrophilic layer 2 is positioned on the outer side of the wound contact layer, and the hydrophobic layer 3 is positioned on the inner side of the wound contact layer; the hydrophobic layer 3 is bonded to the outside of the adhesive layer 4.

The hydrophilic layer 2 and the hydrophobic layer 3 are fibrous, and the complexing mode is that hydrophilic layer fibers and hydrophobic layer fibers are mutually inserted, so that gel generated after the hydrophilic layer 2 absorbs liquid is not easy to fall off, and the service life is prolonged.

After the hydrophilic layer 2 absorbs liquid to form gel, the hydrophobic layer 3 absorbs the gel formed by the hydrophilic layer 2 due to capillary phenomenon, and the hydrophilic layer 2 and the hydrophobic layer 3 are combined to form a layer structure.

The release layer 1 is a single silicon release film; the hydrophilic layer fiber is carboxymethyl cellulose fiber, so that the liquid absorption capacity is high; the hydrophobic layer fiber is terylene; the adhesive layer 4 is white latex, so that the hydrophobic layer 3 is tightly connected with the base material 5 and is adhered to the skin at the same time, thereby playing a role in fixing dressing; the base material 5 is a nonwoven fabric.

EXAMPLE 2 carboxymethyl cellulose wound dressing

The release layer 1 is PE; the hydrophilic layer fiber is carboxymethyl cellulose fiber, so that the liquid absorption capacity is high; the hydrophobic layer fiber is chinlon; the adhesive layer 4 is epoxy adhesive, so that the hydrophobic layer 3 is tightly connected with the base material 5 and is adhered to the skin at the same time, thereby playing a role in fixing the dressing; the substrate 5 is a polyurethane film.

Finally, it should be noted that: the foregoing description is only a preferred embodiment of the present invention, and is not intended to limit the present invention, but although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the technical solutions described in the foregoing embodiments, or equivalents may be substituted for some of the technical features thereof. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A carboxymethyl cellulose wound dressing, which comprises a dressing body, and is characterized in that the dressing body at least comprises a release layer (1), a wound contact layer, an adhesive layer (4) and a base material (5);

the release layer (1), the wound contact layer, the adhesive layer (4) and the base material (5) are sequentially laminated;

the release layer (1) is 2 pages, is overlapped and covered on the outer side of the adhesive layer (4) in a crossing way and extends and covers on the outer side of the wound contact layer; the inner side of the wound contact layer is bonded with the inner side of the base material (5) through the adhesive layer (4);

the wound contact layer comprises a hydrophilic layer (2) and a hydrophobic layer (3), the hydrophilic layer (2) being located on the outer side of the wound contact layer, the hydrophobic layer (3) being located on the inner side of the wound contact layer; the hydrophobic layer (3) is bonded with the outer side of the adhesive layer (4);

the hydrophilic layer (2) and the hydrophobic layer (3) are fibrous, and the complexing mode is that the hydrophilic layer fibers and the hydrophobic layer fibers are mutually penetrated;

the hydrophilic layer fiber is carboxymethyl cellulose fiber, and has strong liquid absorption capacity.

2. A carboxymethyl cellulose wound dressing according to claim 1, characterized in that the wound contact layer, the adhesive layer (4) and the substrate (5) are compounded by a process of needle punching and hot pressing.

3. A carboxymethyl cellulose wound dressing according to claim 1, wherein the release layer (1) is any one of paper, PE, PET, OPP, PC, PS, PMMA, BOPP, a single silicon release film and a teflon release film.

4. A carboxymethyl cellulose wound dressing according to claim 1, wherein the hydrophobic layer fiber is one or more of dacron, chinlon, spandex, polypropylene, polyvinyl chloride, and acrylic.

5. A carboxymethyl cellulose wound dressing according to claim 1, characterized in that the adhesive layer (4) is one or more of white latex, butyl gum, epoxy gum, polyurethane gum, acrylate gum, polyvinyl acetate gum.

6. A carboxymethyl cellulose wound dressing according to claim 1, characterized in that the substrate (5) is a nonwoven or polyurethane film.