CN114686606A - Skin care recommendation method and system based on skin flora - Google Patents
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Abstract
The invention discloses a skin care recommendation method and system based on skin flora, relating to the technical field of biology, wherein the method comprises the following steps: collecting a skin sample, and detecting skin flora; classifying the skin flora according to functions, and grading the flora of each category to obtain a category score; based on the category score, a skin care recommendation is obtained. The skin flora is detected, classified and graded according to categories to reflect the micro-ecological environment of the skin flora, and skin care recommendation is carried out based on the category grading, so that the skin can be managed finely, and the skin health can be improved.
Description
Technical Field
The invention relates to the technical field of biology, in particular to a skin care recommendation method and system based on skin flora.
Background
The skin, as the largest organ of the human body, not only plays the roles of perspiration, cold and heat feeling and pressure, but also plays the role of a 'protector', and effectively protects various tissues and organs in the body from physical, mechanical, chemical and pathogenic microbial attacks. Skin health is increasingly being viewed by people, and more time and resources are spent on skin management.
Healthy skin is not limited to the skin disease, and skin color, anti-acne, anti-wrinkle, moisture retention, and the like are all the evaluation indexes of healthy skin. The health of the skin is related to a number of factors, such as the skin flora, the use of cosmetics, the use of correct cosmetics, etc.
The skin-exterior flora refers to an ecosystem which is composed of various microorganisms such as bacteria, fungi, viruses, mites and arthropods, tissues and cells on the exterior of the skin, various secretions, a microenvironment and the like. They are mainly composed of the interaction of skin microorganisms, hosts and the external environment, which constitute the microecological balance of the skin, and the skin microorganisms are the important components in the balance system. Some strains of skin microorganisms are harmful to skin, and some strains are beneficial to skin, and the single strain detection of the skin flora is mainly used for detecting skin diseases at present and cannot reflect the condition of microecological balance formed by the flora.
Disclosure of Invention
Aiming at the technical problems in the prior art, the invention provides a skin care recommendation method and system based on skin flora, which are used for detecting a collected sample and grading the flora category of the sample, and are beneficial to health management of skin.
The invention discloses a skin care recommendation method based on skin flora, which comprises the following steps: collecting a skin sample, and detecting skin flora; classifying the skin flora according to functions, and grading the flora of each category to obtain a category score; based on the category score, a skin care recommendation is obtained.
Preferably, the method for detecting skin flora comprises:
constructing a gene chip based on the skin flora;
extracting the genome of the skin sample;
after the genome is amplified, hybridizing with the gene chip;
and obtaining a detection result through chip scanning, wherein the detection result comprises the type and name of the obtained skin flora.
Preferably, the skin flora comprises one or a combination of the following: resisting aging, removing wrinkle, controlling oil, keeping moisture, resisting black and speckle, and relieving inflammation and acne.
Preferably, the method of scoring the flora of each category comprises:
screening florae according to the categories to obtain a first florae;
scoring the strains of the first flora according to the degree of harm or benefit to obtain strain scores;
and (4) carrying out weighted sum on the scores of the strains in the first flora to obtain the score of the first flora.
Preferably, the formula for scoring by hazard or benefit programs is:
wherein, the levelfloraExpressed as strain scores;
the formula for summing the scores of the species in the first population is:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the strains obtained by the detection,
expressed as the sum of the species scores.
Preferably, the formula for scoring by a hazardous or beneficial procedure is:
wherein, the levelfloraExpressed as strain scores;
and according to the weight and the content of the strains, performing weighted sum on the scores of the strains in the first flora:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the strains obtained by the detection,
expressed as a summation, where λ is a weight index and C is the percentage of species content detected by the skin flora.
Preferably, the method of obtaining skin care recommendations comprises:
setting a threshold value of harmful bacteria;
judging whether the detection result of the skin flora is higher than a threshold value;
if yes, the antibacterial or anti-inflammatory treatment is recommended;
and if not, generating a functional skin care recommendation according to the category score.
Preferably, the functional skin care recommendation includes one or a combination of the following: resisting aging, removing wrinkle, controlling oil, keeping moisture, resisting black and speckle, and relieving inflammation and acne.
The invention also provides application of the method, and the method is applied to skin care product ingredient recommendation or cosmetic recommendation.
The invention also provides a system for realizing the method, which comprises a flora detection module, a scoring module and a recommending module,
the flora detection module is used for collecting skin samples and detecting skin flora;
the grading module is used for classifying skin flora according to functions, grading flora of each class and obtaining class grade;
and the recommending module is used for obtaining skin care recommendation according to the category scores.
Compared with the prior art, the invention has the beneficial effects that: the skin flora is detected, classified and graded according to categories to reflect the micro-ecological environment of the skin flora, and skin care recommendation is performed based on the graded according to the categories, so that the skin is conveniently and finely managed, and the skin health is favorably improved; skin care recommendations may include recommendations for antimicrobial agents, recommendations for anti-aging anti-wrinkle treatments, recommendations for appropriate anti-skin ingredients, or recommendations for appropriate cosmetics to modulate flora and micro-ecology.
Drawings
FIG. 1 is a flow chart of a method of skin care recommendation based on skin flora of the present invention;
FIG. 2 is a flow chart of a method of detecting skin flora;
FIG. 3 is a flow chart of a method for scoring the flora of each category;
FIG. 4 is a flow diagram of a method of obtaining skin care recommendations;
fig. 5 is a logic block diagram of the system of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
The invention is described in further detail below with reference to the attached drawing figures:
a method for skin care recommendation based on skin flora, as shown in fig. 1, the method comprising:
step 101: skin samples were collected and tested for skin flora. The skin can be sampled at multiple points, and the detection of skin flora can be performed by a gene chip method, but is not limited to the method.
Step 102: classifying the skin flora according to functions, and scoring the flora of each category to obtain category scores. The category score may be obtained by weighted summation of the species scores under each category. The categories may include one or a combination of the following: resisting aging and wrinkle, controlling oil and keeping moisture, resisting black and speckle, and relieving inflammation and acne.
Step 103: based on the category score, a skin care recommendation is obtained. Wherein, the score is the quantification of the strains, the category score is the quantification of the categories, and the skin flora can be compared or compared quantitatively and qualitatively through the quantification. For example, when harmful bacteria species are detected, bacteriostasis or cleaning is recommended, and when beneficial bacteria are detected, the types of the beneficial bacteria and the skin care recommendation method are displayed to the examinee.
The skin flora is detected, classified and classified according to the classification, so that the micro-ecological environment of the skin flora is reflected, and skin care recommendation is performed based on the classification, so that the skin is conveniently and finely managed, and the skin health is favorably improved; skin care recommendations may include recommendations for antimicrobial agents, recommendations for anti-aging anti-wrinkle treatments, recommendations for appropriate anti-skin ingredients, or recommendations for appropriate cosmetics to modulate flora and micro-ecology.
As shown in fig. 2, the method for detecting skin flora includes:
step 201: and constructing a gene chip based on the skin flora. For example, specific gene probes can be designed based on the strains of the flora, and control probes are fixed in a gene chip. The gene chip is the prior art, and is not described in detail in the invention.
Step 202: the genome of the skin sample was extracted.
Step 203: and after the genome is amplified, hybridizing with the gene chip.
Step 204: and obtaining a detection result by scanning the chip, wherein the detection result comprises the type and the name of the skin flora. The hybridized gene probe is obtained by scanning the chip, the corresponding strain name of the gene probe is obtained by analyzing the gene probe, and the collection of all strains forms the skin flora. Wherein, the content percentage of the strain can be calculated according to the signal intensity of the gene probe. The detection principle of gene chip is hybridization sequencing method, in which the probe of strain target nucleotide with known sequence is fixed on the surface of substrate, and when the nucleic acid sequence with fluorescent label in the sample is complementarily matched with the probe in the correspondent position on the gene chip, a group of probes with completely complementary sequences and sample sequences can be obtained by means of fluorescence intensity, so that the skin strain and flora can be detected.
The detection is carried out by a gene chip method, which is beneficial to shortening the detection period and improving the detection efficiency. But not limited thereto, the species of the bacterial flora may also be detected by other means, such as gene sequencing or functional identification.
As shown in fig. 3, the method of scoring the flora of each category includes:
step 301: and screening florae according to the categories to obtain a first florae.
Step 302: and scoring the strains of the first flora according to the harm or benefit degree to obtain strain scores.
Step 303: and (4) carrying out weighted sum on the scores of the strains in the first flora to obtain the score of the first flora.
Example 1
Wherein the model for scoring by hazard or benefit programs is:
wherein, the levelfloraExpressed as strain score;
the formula for summing the scores of the species in the first population is:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the strains obtained by the detection,
expressed as the sum of the strain scores.
Example 2
Different from the embodiment 1, in the first flora score, the bacterial species score in the first flora is weighted according to the weight and the content of the bacterial species:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the strains obtained by the detection,
expressed as the sum of the bacterial species scores, wherein lambda is a weight index, and C is the content percentage of the bacterial species detected by the skin flora. In the gene chip detection, the strain is judged to be positive or negative by scanning the fluorescence intensity of the gene probe on the hybridized gene chip, and the fluorescence intensity is in direct proportion to the gene abundance, so the strain content percentage C can be obtained according to the ratio of the fluorescence intensity, for example, the sum of the fluorescence intensities of the positive gene probe is calculated as the total bacterial population, the probe fluorescence intensity of the strain is taken as the total bacterial population, the ratio of the total bacterial population to the total bacterial population is taken as the strain content percentage C, and the weight lambda of different strains can be different.
Example 3
As shown in fig. 4, a method of obtaining skin care recommendations includes:
step 401: a threshold value for harmful bacteria is set. The threshold value can be that the content of harmful bacteria exceeds a certain value, or the detection result of highly harmful bacteria is positive.
Step 402: and judging whether the detection result of the skin flora is higher than a threshold value.
If yes, go to step 403: an antibacterial or anti-inflammatory treatment is recommended. If the content of the harmful bacteria exceeds 50 percent or the harmful bacteria have high-risk pathogenic bacteria, the antibacterial or anti-inflammatory treatment is recommended.
If not, go to step 404: generating a functional skin care recommendation based on the category score. Wherein the functional skin care recommendation may include one or a combination of: antibacterial, antiinflammatory, cleaning, moisturizing, wrinkle resisting, acne resisting, and oil controlling.
According to the functional recommendation, the skin care product component or cosmetic with the function can be obtained, if the recommended function is bacteriostasis, the skin care product component or cosmetic with the bacteriostasis function can be obtained, such as common antibacterial components of white willow bark, scutellaria baicalensis, sophora flavescens and salvia; the anti-inflammatory skin care product comprises Glycyrrhrizae radix, bisabolol, nicotinamide, B5 and ectoin.
Thus, the method of the present invention may also be applied to skin care ingredient recommendation skin care or cosmetic recommendation. Matching the corresponding skin care product or cosmetic according to the recommended skin care product components.
In one embodiment, the common species are shown in the following table:
however, the species detected in the skin is not limited thereto.
In another aspect, the present invention further provides a system for implementing the method, as shown in fig. 5, comprising a flora detection module 1, a scoring module 2 and a recommendation module 3,
the flora detection module 1 is used for collecting skin samples and detecting skin flora;
the scoring module 2 is used for classifying skin flora according to functions, scoring the flora of each category and obtaining category scores;
and the recommending module 3 is used for obtaining skin care recommendation according to the category scores.
The system of the invention may further comprise a second recommending module 4, wherein the second recommending module 4 is configured to obtain a skin care composition recommendation or a cosmetic recommendation according to the category score or the skin care recommendation.
The above is only a preferred embodiment of the present invention, and is not intended to limit the present invention, and various modifications and changes will occur to those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A method for skin care recommendation based on skin flora, the method comprising:
collecting a skin sample, and detecting skin flora;
classifying the skin flora according to functions, and scoring the flora of each category to obtain category scores;
based on the category score, a skin care recommendation is obtained.
2. The method of skin flora-based skin care recommendation according to claim 1, wherein the method of detecting skin flora comprises:
constructing a gene chip based on the skin flora;
extracting the genome of the skin sample;
after the genome is amplified, hybridizing with the gene chip;
and obtaining a detection result through chip scanning, wherein the detection result comprises the type and the name of the skin flora.
3. The method for skin flora-based skin care recommendation according to claim 1, wherein the skin flora category comprises one or a combination of the following: resisting aging, removing wrinkle, controlling oil, keeping warm, resisting black, resisting speckle, resisting inflammation, and eliminating acne.
4. The method of skin flora-based skin care recommendation according to claim 1, wherein the method of scoring each category of flora comprises:
screening florae according to the categories to obtain a first florae;
scoring the strains of the first flora according to the degree of harm or benefit to obtain strain scores;
and (4) carrying out weighted sum on the scores of the strains in the first flora to obtain the score of the first flora.
5. The method of skin flora-based skin care recommendation according to claim 4, wherein the model for scoring as hazardous or beneficial procedure is:
wherein, the levelfloraExpressed as strain score;
the formula for summing the scores of the species in the first population is:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the detected species.
6. The method of skin flora-based skin care recommendation according to claim 4, wherein the formula for scoring as hazardous or beneficial procedure is:
wherein, the levelfloraExpressed as strain score;
and according to the weight and the content of the strains, performing weighted sum on the scores of the strains in the first flora:
wherein score _ flora is the score of the first flora, (result)flora)iExpressed as the detected strains, wherein lambda is a weight index, and C is the content percentage of the strains detected by the skin flora.
7. The method of skin flora-based skin care recommendation according to claim 1, wherein the method of obtaining skin care recommendation comprises:
setting a threshold value of harmful bacteria;
judging whether the detection result of the skin flora is higher than a threshold value;
if yes, the antibacterial or anti-inflammatory treatment is recommended;
and if not, generating a functional skin care recommendation according to the category score.
8. The method of skin flora-based skin care recommendation according to claim 7, wherein said functional skin care recommendation comprises one or a combination of: resisting aging, removing wrinkle, controlling oil, keeping warm, resisting black, resisting speckle, resisting inflammation, and eliminating acne.
9. Use of the method of any one of claims 1 to 8 in a skin care ingredient recommendation skin care or cosmetic recommendation.
10. A system for implementing the method of any one of claims 1 to 8, comprising a flora detection module, a scoring module and a recommendation module,
the flora detection module is used for collecting skin samples and detecting skin flora;
the grading module is used for classifying skin flora according to functions, grading flora of each class and obtaining class grade;
and the recommending module is used for obtaining skin care recommendation according to the category scores.
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| CN116064875A (en) * | 2023-01-09 | 2023-05-05 | 西湖迷微(杭州)生物科技有限公司 | Method for predicting skin quality based on skin bacteria high-throughput sequencing data and application |
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