CN114668698A - 一种植物成分漱口水 - Google Patents

一种植物成分漱口水 Download PDF

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CN114668698A
CN114668698A CN202210496108.9A CN202210496108A CN114668698A CN 114668698 A CN114668698 A CN 114668698A CN 202210496108 A CN202210496108 A CN 202210496108A CN 114668698 A CN114668698 A CN 114668698A
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extract
water
hydrochloride
marine
mouthwash
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王久儒
荆立君
彭彤
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Qingdao Xinjing Medical Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/604Alkylpolyglycosides; Derivatives thereof, e.g. esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/736Chitin; Chitosan; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

Abstract

本发明提供了一种以植物成分为主不含氟氯不含酒精的漱口水及其制备方法,所述的漱口水中按质量百分比包括盐酸盐聚六亚甲基胍、松针提取物、防风提取物、水溶性壳聚糖、金银花提取物、海生活素聚多糖、生物酶、十二烷基葡萄糖苷及罗汉果甜苷等成分。本发明所述的植物提取漱口水,可以减少对口腔刺激的同时清洁牙齿及牙龈表面污垢,对口腔环境进行杀菌,长效保持口气清新及口腔健康,安全性高,制备方法简单。

Description

一种植物成分漱口水
技术领域
本发明属于日常用品领域,涉及一种漱口水。
背景技术
漱口水是一种新型口腔保健用品,主要作用是去除口臭,可对口腔常见疾病进行辅助治疗。在欧美国家漱口水已经成为口腔日常护理的必备产品,与牙膏所占比例不相上下,但是在我国牙膏和牙刷占口腔护理用品消费的比例达97%,而漱口水还不足3%,仍然处于市场培育和渗透的阶段。
漱口水对多种口腔疾病有治疗作用,对口腔异味有清除功能,在各种环境下都能使用的方便性,非常适合广大百姓使用,随着社会的发展,漱口水将会成为人们生活中不可缺少的日用品。常见的漱口水主要组分为香精、表面活性剂、氟化物、氯化锶、酒精和水等,能清洁口腔,预防龋齿和牙周炎等。但漱口水因其主要成分的特异性也存在诸多弊端如漱口水容易造成溃疡、会造成灼热等给人带来不适。
本发明植物配方漱口水主要用由紫丁香提取物盐酸盐聚六亚甲基胍、松针提取物防风提取物、水溶性壳聚糖、金银花提取物、海生活素聚多糖、生物酶、十二烷基葡萄糖苷及罗汉果甜苷等,将中草药的药理特性与消毒灭菌的基本原理相结合,打造一款不含酒精不含氟的可用于保护全口腔健康的漱口水。
发明内容
本发明植物配方漱口水主要用由紫丁香提取物盐酸盐聚六亚甲基胍、松针提取物防风提取物、水溶性壳聚糖、金银花提取物、海生活素聚多糖、生物酶、十二烷基葡萄糖苷及罗汉果甜苷等合成,漱口水采用盐酸盐聚六亚甲基胍配合植物提取物为原料,属广谱杀菌剂,植物复配得到的杀菌体系可有效维持口腔菌态平衡,有效预防和改善由细菌所引起的牙龈肿痛、牙龈出血、口腔溃疡、口臭等;十二烷基葡萄糖苷作为优秀的表面活性剂可在复杂的口腔环境中有效去除有机残污,在清洁效果得以保障的前提下再杀菌;添加市面上常见但鲜用于漱口水的罗汉果甜苷作为甜度调节剂,罗汉果甜苷甜度约为蔗糖的100-250倍,少量添加即可保证口感,同时属于零热量添加剂,无负担。漱口水稳定性良好,安全性好,对皮肤粘膜无刺激。
本发明选择的配方如下(组分及其重量百分比%):
盐酸盐聚六亚甲基胍0.1-0.8、松针提取物0.2-0.5、防风提取物0.2-0.5、水溶性壳聚糖0.2-1.0、金银花提取物0.1-1.0、海生活素聚多糖0.3-1.0、生物酶0.01-0.05、十二烷基葡萄糖苷0.15-0.25及罗汉果甜苷0.01-0.10,净化水加至100。
具体实施方式:
下面结合实施例对本发明作进一步的详细说明:
按照下表所列数据(重量百分比%)及其所述步骤进行配置:
配方一:
盐酸盐聚六亚甲基胍 0.1-0.2
松针提取物 0.2-0.5
防风提取物 0.1-0.3
水溶性壳聚糖 0.2-0.5
金银花提取物 0.5-1.0
海生活素聚多糖 0.3-0.5
生物酶 0.01-0.05
十二烷基葡萄糖苷 0.15-0.20
罗汉果甜苷 0.01-0.05
净化水加 至100
配方二:
盐酸盐聚六亚甲基胍 0.2-0.8
松针提取物 0.1-0.5
防风提取物 0.1-0.5
水溶性壳聚糖 0.2-1.0
金银花提取物 0.5-1.0
海生活素聚多糖 0.3-0.5
生物酶 0.01
十二烷基葡萄糖苷 0.15-0.20
罗汉果甜苷 0.05-0.10
净化水加 至100
配方三:
盐酸盐聚六亚甲基胍 0.2-0.5
松针提取物 0.3-0.5
防风提取物 0.2-0.5
水溶性壳聚糖 0.2-0.8
金银花提取物 0.1-0.5
海生活素聚多糖 0.3-1.0
生物酶 0.01-0.05
十二烷基葡萄糖苷 0.15-0.25
罗汉果甜苷 0.01-0.05
净化水加 至100

Claims (8)

1.植物配方漱口水是盐酸盐聚六亚甲基胍、松针提取物、防风提取物、水溶性壳聚糖、金银花提取物、海生活素聚多糖、生物酶、十二烷基葡萄糖苷及罗汉果甜苷等成分构成。
2.如权利要求1所述的植物配方漱口水,其特征在于,包含如下(组分及其重量百分比%):盐酸盐聚六亚甲基胍0.1-0.8、松针提取物0.2-0.5、防风提取物0.2-0.5、水溶性壳聚糖0.2-1.0、金银花提取物0.1-1.0、海生活素聚多糖0.3-1.0、生物酶0.01-0.05、十二烷基葡萄糖苷0.15-0.25及罗汉果甜苷0.01-0.10。
3.如权利要求1和2中所述的盐酸盐聚六亚甲基胍、松针提取物、防风提取物、水溶性壳聚糖、金银花提取物、海生活素聚多糖是在不同植物或者海洋生物中提取的同类物质。
4.如权利要求1和2中所述的松针、防风、金银花等植物提取物配置方法如下:将金银花粉碎、苦丁茶、蒲公英粉碎200目,进行水性提取,并进行活性炭吸附脱色、浓缩处理至需要浓度备用。
5.如权利要求1和2中所述的十二烷基葡萄糖苷为无毒、无害、对皮肤无刺激,生物降解迅速彻底,属于性能全面的绿色表面活性剂。
6.如权利要求1和2中所述的罗汉果甜苷属于天然代糖,甜度是蔗糖的100-250倍。
7.如权利要求1~2任一项所述的消毒植物配方漱口水的制备方法,其特征在于,包括以下步骤:将金银花粉碎、松针、防风粉碎200目,进行水性提取,并进行活性炭吸附脱色、浓缩处理至需要浓度备用;将海洋生物壳聚糖按照比例溶解备用,将海洋生物抗菌肽按照比例稀释备用;将紫丁香提取物盐酸盐聚六亚甲基胍稀释至一定浓度备用;将搅拌罐加入适量水,加温到40℃,缓慢加入壳聚糖,搅拌10min,至完全溶解;将盐酸盐聚六亚甲基胍加入到搅拌罐中,搅拌20min,并降温至常温,25℃左右;依次加入植物多糖提取物、芳香烃提取物、生物碱提取物、海洋生物抗菌多肽搅拌15min;将十二烷基葡萄糖苷及罗汉果甜苷按配置比例加入到上述液体中。
8.根据权利要求7所述的制备方法,其特征在于:所有的原材料的加入,需要严格控制好加料顺序。
CN202210496108.9A 2022-05-10 2022-05-10 一种植物成分漱口水 Withdrawn CN114668698A (zh)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648095A (zh) * 2017-09-14 2018-02-02 山东新华医疗器械股份有限公司 罗汉果糖苷漱口水及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648095A (zh) * 2017-09-14 2018-02-02 山东新华医疗器械股份有限公司 罗汉果糖苷漱口水及其制备方法

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Application publication date: 20220628