CN114668562A - Novel bioactive zero-notch cervical vertebra fusion cage - Google Patents
Novel bioactive zero-notch cervical vertebra fusion cage Download PDFInfo
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- CN114668562A CN114668562A CN202210297173.9A CN202210297173A CN114668562A CN 114668562 A CN114668562 A CN 114668562A CN 202210297173 A CN202210297173 A CN 202210297173A CN 114668562 A CN114668562 A CN 114668562A
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- 230000004927 fusion Effects 0.000 title claims abstract description 42
- 230000000975 bioactive effect Effects 0.000 title claims abstract description 20
- 230000002093 peripheral effect Effects 0.000 claims abstract description 15
- 230000007935 neutral effect Effects 0.000 claims abstract description 10
- 241000561734 Celosia cristata Species 0.000 claims description 4
- 210000001520 comb Anatomy 0.000 claims description 4
- 230000004071 biological effect Effects 0.000 claims description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 abstract description 9
- 239000010936 titanium Substances 0.000 abstract description 9
- 229910052719 titanium Inorganic materials 0.000 abstract description 9
- 208000019505 Deglutition disease Diseases 0.000 abstract description 3
- 208000026137 Soft tissue injury Diseases 0.000 abstract description 3
- 210000000988 bone and bone Anatomy 0.000 description 20
- 239000000463 material Substances 0.000 description 10
- 239000011148 porous material Substances 0.000 description 7
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 7
- 229910000831 Steel Inorganic materials 0.000 description 6
- 239000010959 steel Substances 0.000 description 6
- 238000010883 osseointegration Methods 0.000 description 5
- 229910052715 tantalum Inorganic materials 0.000 description 5
- 238000000034 method Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- 238000011282 treatment Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 208000024248 Vascular System injury Diseases 0.000 description 2
- 208000012339 Vascular injury Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 208000015122 neurodegenerative disease Diseases 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 230000035882 stress Effects 0.000 description 2
- 230000009747 swallowing Effects 0.000 description 2
- 208000000094 Chronic Pain Diseases 0.000 description 1
- 208000000860 Compassion Fatigue Diseases 0.000 description 1
- 241000167880 Hirundinidae Species 0.000 description 1
- 208000024297 Laryngeal Nerve injury Diseases 0.000 description 1
- 206010058522 Oesophageal injury Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010041591 Spinal osteoarthritis Diseases 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 208000036319 cervical spondylosis Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000005786 degenerative changes Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
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- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 208000005801 spondylosis Diseases 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 238000011277 treatment modality Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
- A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
- A61F2002/30772—Apertures or holes, e.g. of circular cross section
- A61F2002/30784—Plurality of holes
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- Oral & Maxillofacial Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
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- Dermatology (AREA)
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Abstract
The invention discloses a novel bioactive zero-notch cervical fusion cage, which comprises a main body, an adjuster and an interface screw; the body comprises a central region and a peripheral region; the middle of the main body is a central area, and the peripheral area is arranged on the periphery of the central area; the adjuster and the interface screw are arranged on the outer wall of the peripheral zone; the two ends of the regulator 2 are serrated edges, the interface screw is fixedly arranged on the main body, and when the regulator rotates to a neutral position, the serrated edges are fixed with the embedded adjacent vertebral bodies and the interface screw by rotating the regulator. The zero-incisura intervertebral fusion device required by the novel cervical vertebra fusion device combines the front end of the fusion device with a self-locking device and an interface screw. Compared with the traditional titanium plate internal fixation system, the novel titanium plate internal fixation system can reduce soft tissue injury in operation, reduce dysphagia complications after operation and improve the satisfaction degree of patients.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a novel bioactive zero-notch cervical fusion cage.
Background
With the development of the socioeconomic level, the life style of people gradually changes. In China, the population aging is intensified, the long-term work staff and the head-lowering family are increased, and the number of patients with cervical vertebra degenerative diseases is increased year by year and is in a youthful trend. For many patients, the clinical symptoms of cervical spondylosis patients cannot be relieved by related conservative treatment modes such as drug treatment, traditional Chinese medicine treatment, even rehabilitation physiotherapy and the like. Surgical treatment becomes an important treatment modality for such patients.
Currently, the main clinical surgical methods include anterior cervical discectomy and decompression bone fusion (ACDF), Artificial Cervical Disc Replacement (ACDR), and other surgical methods. ACDF operation is still clinically selected at present in view of high cost of artificial cervical intervertebral discs and strict operation indications. The ideal material for repair of bone defects between vertebral bodies following ACDF surgery is autologous graft (e.g., iliac crest autograft) filling. However, the amount of the autogenous bone is small, secondary trauma is easy to cause, and complications are relatively high, so the autogenous bone is replaced by the intervertebral fusion cage in clinic. Compared with the autologous bone transplantation, the interbody fusion cage can immediately restore the intervertebral height or the physiological curvature of the vertebral body. Meanwhile, the gradually fusing device with the porous structure can increase the aperture of the intervertebral space, improve the bone grafting fusion rate, finally reduce the complications of bone collapse, infection, chronic pain and the like, and promote the recovery of patients.
Meanwhile, cervical fusion is the gold standard for treating degenerative diseases such as intervertebral disc, and the currently common operation mode is usually fixed by adding a steel plate under the condition of applying the intervertebral fusion device. The operation mode is easy to cause the steel plate to shift due to the loosening of the screw, and the steel plate is placed in the esophagus for a long time to cause potential damage. The steel plate is arranged on the surface of the cervical vertebra, so that the possibility that a patient feels foreign bodies in swallowing or swallows difficultly and even suffers from laryngeal nerve injury exists for a long time. Therefore, new bioactive materials are receiving more and more attention to making the zero-notch cervical fusion cage.
From the structure of the cervical vertebra fusion cage, the most common clinical application is the most common application of the titanium nail plate internal fixing system at present. It can increase the stability of reconstructed cervical vertebra, raise bone grafting fusion rate and lower the sinking rate of fusion device. In contrast, the anterior titanium intralamellar fixation system surgery also results in potential esophageal injury and postoperative discomfort to the patient from swallowing for a long period of time. The greater rigidity of the titanium nail plate can cause the stress of the adjacent vertebral body segment after internal fixation to be increased, and the degenerative change is accelerated.
Disclosure of Invention
In order to solve the problems in the prior art, the embodiment of the invention provides a novel bioactive zero-notch cervical fusion cage. The technical scheme is as follows:
in one aspect, a novel bioactive zero notch cervical fusion cage is provided, including: a body, an adjuster, and an interface screw; the body comprises a central region and a peripheral region; the middle of the main body is a central area, and the peripheral area is arranged on the periphery of the central area; the adjuster and the interface screw are arranged on the outer wall of the peripheral zone;
the both ends of regulator 2 are the cockscomb structure edge, interface screw fixed set up in on the main part, when the regulator is rotatory to neutral position, make cockscomb structure edge and embedding adjacent centrum and interface screw fixed through rotatory the regulator.
Further, the adjuster comprises a knob, and the knob adopts a hollow thread structure; the main body is provided with a thread groove; the adjuster is rotated to a neutral position by the thread groove.
Further, the regulator further comprises a rotary rod; the rotary rods are arranged on two sides of the rotary knob, and the tail ends of the rotary rods are saw-toothed edges.
Further, the central region employs a high porosity.
Further, the peripheral zone employs a low porosity.
The technical scheme provided by the embodiment of the invention has the following beneficial effects:
1. the novel cage can be made of bioactive trabecular metal (porous tantalum material) or potentially other bioactive materials. The porosity of the porous material is high, and on the premise of ensuring mechanical support, the porous material can promote nutrient exchange in human body environment, promote bone ingrowth and osseointegration, and finally promote patient recovery.
2. The interbody fusion cage designed by the method is based on the centrum anatomical data of Chinese people, and the adopted arc design is more matched with the centrum of a human body, so that the centrum sedimentation rate is reduced, and the application range is wider
3. The zero-incisura intervertebral fusion device required by the novel cervical vertebra fusion device combines the front end of the fusion device with a self-locking device and an interface screw. Compared with the traditional titanium plate internal fixation system, the novel titanium plate internal fixation system can reduce soft tissue injury in operation, reduce dysphagia complications after operation and improve the satisfaction degree of patients.
4. This novel cervical vertebra fuses ware does not need additionally to plant the bone, does not need the screw steel sheet fixed, has reduced muscle in the art, and the vascular injury risk reduces the operation risk, can indirectly promote the osseointegration.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a front view of a novel bioactive zero notch cervical fusion cage according to an embodiment of the present invention;
FIG. 2 is a front view of a novel bioactive zero notch cervical fusion cage according to an embodiment of the present invention;
FIG. 3 is a central side sectional view of the novel bioactive zero notch cervical fusion cage according to an embodiment of the present invention;
fig. 4 is a top view of a novel bioactive zero notch cervical fusion cage according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, embodiments of the present invention will be described in detail with reference to the accompanying drawings.
The invention provides a novel bioactive zero-notch cervical fusion cage, which is shown in figures 1-4 and comprises: a body 1, an adjuster 2 and an interface screw 3; the main body 1 comprises a central zone 11 and a peripheral zone 12; the middle of the main body 1 is a central area 11, and the peripheral area 12 is arranged on the periphery of the central area 11; the adjuster 2 and the interface screw 3 are both arranged on the outer wall of the peripheral zone 12;
the two ends of the regulator 2 are serrated edges, the interface screw 3 is fixedly arranged on the main body 1, and when the regulator 2 rotates to a neutral position, the serrated edges are fixed with the embedded adjacent vertebral bodies and the interface screw by rotating the regulator.
Specifically, the position of the interface screw is fixed, that is, the interface screw is locked after the adjuster is rotated to the neutral position, so as to prevent the adjuster from being shifted too much; at the same time, the rotation of the regulator to the neutral position is intended to insert the upper and lower vertebral bodies, respectively, to fix them and finally to promote bone fusion.
In this embodiment, the intervertebral fusion cage is fixed by rotating the adjuster in front of the fusion cage to lock the upper and lower vertebral bodies, and after the adjuster rotates to the neutral position, an additional interface screw is added for fixing again to prevent displacement.
Further, the adjuster comprises a knob, and the knob adopts a hollow thread structure; the main body is provided with a thread groove; the adjuster is rotated to a neutral position by the thread groove.
Further, the regulator further comprises a rotary rod; the rotary rods are arranged on two sides of the knob, and the tail ends of the rotary rods are provided with saw-toothed edges.
Specifically, the regulator adopts a rotary regulator, and the middle circle of the regulator is designed into a thread structure and is rotated to a target position. Meanwhile, the sawtooth grooves of the rotary rod are utilized, the middle thread groove track is utilized to be inserted into the adjacent upper and lower vertebral bodies counterclockwise by 90 degrees, and the vertebral bodies are locked.
Further, the central region employs a high porosity. The peripheral zone employs a low porosity.
Specifically, the pore diameter of the porous material is adjusted by the actual characteristics of different materials on the premise of determining the lowest compressive strength of the interbody fusion cage.
In this embodiment, the cervical fusion cage is made of trabecular bone metal (porous tantalum material) with biological activity or potentially other biological active materials; the reason is as follows:
1. according to the characteristics of biological materials made of different materials, the pore diameters, the porosity and the mechanical strength of the materials can be adjusted, so that the bone tissue of a human body is simulated, the elastic modulus is close to that of normal bone, the stress shielding can be reduced, the bone ingrowth can be promoted, and the bone integration can be promoted.
2. The porous tantalum has a three-dimensional structure with holes similar to human cancellous bone and communicated with each other, has high porosity, can promote nutrient exchange in the holes, is more favorable for bone ingrowth and promotes osseointegration; porous tantalum.
3. Can construct a porous structure, and design a fusion cage which can better meet the characteristics of Chinese people through different specifications, thereby meeting the biomechanical requirements of cervical vertebra.
The technical scheme provided by the embodiment of the invention has the following beneficial effects:
1. the novel cage can be made of bioactive trabecular metal (porous tantalum material) or potentially other bioactive materials. The porosity of the porous material is high, and on the premise of ensuring mechanical support, the porous material can promote nutrient exchange in human body environment, promote bone ingrowth and osseointegration, and finally promote patient recovery.
2. The interbody fusion cage designed herein is based on the centrum anatomical data of Chinese people, and the adopted arc design is more matched with the centrum of human body, so that the centrum sedimentation rate is reduced, and the application range is wider
3. The zero-incisura intervertebral fusion device required by the novel cervical vertebra fusion device combines the front end of the fusion device with a self-locking device and an interface screw. Compared with the traditional titanium plate internal fixing system, the novel titanium plate internal fixing system can reduce soft tissue injury in operation, reduce dysphagia complications after operation and improve the satisfaction degree of patients.
4. This novel cervical vertebra fuses ware does not need additionally to plant the bone, does not need the screw steel sheet fixed, has reduced muscle in the art, and the vascular injury risk reduces the operation risk, can indirectly promote the osseointegration.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent replacements, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (5)
1. The utility model provides a novel zero notch cervical vertebra of biological activity fuses ware which characterized in that includes: a body, an adjuster, and an interface screw; the body comprises a central region and a peripheral region; the middle of the main body is a central area, and the periphery of the central area is provided with the peripheral area; the adjuster and the interface screw are arranged on the outer wall of the peripheral zone;
the both ends of regulator 2 are the cockscomb structure edge, interface screw fixed set up in on the main part, when the regulator is rotatory to neutral position, make cockscomb structure edge and embedding adjacent centrum and interface screw fixed through rotatory the regulator.
2. The novel bioactive zero notch cervical fusion cage according to claim 1, wherein the adjuster comprises a knob, the knob is of a hollow thread structure; the main body is provided with a thread groove; the adjuster is rotated to a neutral position by the thread groove.
3. The novel bioactive zero notch cervical fusion cage of claim 2, wherein said actuator further comprises a rotating rod; the rotary rods are arranged on two sides of the rotary knob, and the tail ends of the rotary rods are saw-toothed edges.
4. The novel bioactive zero notch cervical fusion cage of claim 1 wherein said central zone is of high porosity.
5. The novel bioactive zero notch cervical fusion cage of claim 1 wherein said peripheral zone is of low porosity.
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CN202210297173.9A CN114668562A (en) | 2022-03-24 | 2022-03-24 | Novel bioactive zero-notch cervical vertebra fusion cage |
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CN202210297173.9A CN114668562A (en) | 2022-03-24 | 2022-03-24 | Novel bioactive zero-notch cervical vertebra fusion cage |
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US20110230971A1 (en) * | 2009-04-15 | 2011-09-22 | Synthes Usa, Llc | Arcuate fixation member |
US20130073045A1 (en) * | 2011-09-21 | 2013-03-21 | Tov Inge Vestgaarden | Method and apparatus for spinal interbody fusion including fixation or locking plate |
US20150142114A1 (en) * | 2013-11-21 | 2015-05-21 | Perumala Corporation | Intervertebral Disk Cage and Stabilizer |
CN108578019A (en) * | 2018-04-12 | 2018-09-28 | 深圳清华大学研究院 | Rotate zero incisura Invasive lumbar fusion device of fixed anterior cervical vertebrae |
CN110236746A (en) * | 2019-06-19 | 2019-09-17 | 重庆医科大学附属第三医院(捷尔医院) | A kind of cervical vertebral fusion cage |
CN112294497A (en) * | 2020-11-23 | 2021-02-02 | 博能华医疗器械(北京)有限公司 | Zero-notch interbody fusion cage |
KR20210020748A (en) * | 2020-03-30 | 2021-02-24 | 주식회사 엔닥 | Cage for vertebra |
CN215535338U (en) * | 2021-06-16 | 2022-01-18 | 浙江科惠医疗器械股份有限公司 | Anterior cervical locking fusion cage |
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2022
- 2022-03-24 CN CN202210297173.9A patent/CN114668562A/en active Pending
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US20050049590A1 (en) * | 2003-03-07 | 2005-03-03 | Neville Alleyne | Spinal implant with securement spikes |
EP2065016A1 (en) * | 2007-11-27 | 2009-06-03 | Jin-Fu Lin | Trans-vertebral and intra-vertebral plate and fusion cage device for spinal interbody fusion and method of operation |
US20100185289A1 (en) * | 2009-01-20 | 2010-07-22 | Incite Innovation Llc | Interbody fusion device and method of operation |
US20110230971A1 (en) * | 2009-04-15 | 2011-09-22 | Synthes Usa, Llc | Arcuate fixation member |
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CN108578019A (en) * | 2018-04-12 | 2018-09-28 | 深圳清华大学研究院 | Rotate zero incisura Invasive lumbar fusion device of fixed anterior cervical vertebrae |
CN110236746A (en) * | 2019-06-19 | 2019-09-17 | 重庆医科大学附属第三医院(捷尔医院) | A kind of cervical vertebral fusion cage |
KR20210020748A (en) * | 2020-03-30 | 2021-02-24 | 주식회사 엔닥 | Cage for vertebra |
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