CN114660312A - Sample analysis equipment - Google Patents

Sample analysis equipment Download PDF

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Publication number
CN114660312A
CN114660312A CN202210570515.XA CN202210570515A CN114660312A CN 114660312 A CN114660312 A CN 114660312A CN 202210570515 A CN202210570515 A CN 202210570515A CN 114660312 A CN114660312 A CN 114660312A
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CN
China
Prior art keywords
sample
assembly
pusher dog
conveying mechanism
finger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210570515.XA
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Chinese (zh)
Inventor
易奇浩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Dymind Biotechnology Co Ltd
Original Assignee
Shenzhen Dymind Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Dymind Biotechnology Co Ltd filed Critical Shenzhen Dymind Biotechnology Co Ltd
Priority to CN202210570515.XA priority Critical patent/CN114660312A/en
Publication of CN114660312A publication Critical patent/CN114660312A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0418Plate elements with several rows of samples
    • G01N2035/042Plate elements with several rows of samples moved independently, e.g. by fork manipulator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/046General conveyor features
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/046General conveyor features
    • G01N2035/0465Loading or unloading the conveyor

Abstract

A sample analysis device includes a transport mechanism, a loading mechanism, and a stop mechanism. The conveying mechanism is used for conveying the sample rack loaded on the conveying mechanism to the detection position; the loading mechanism is used for pushing the multi-row sample racks to the conveying mechanism integrally so that the sample racks in the multi-row sample racks can be pushed onto the conveying mechanism in sequence; the stopping mechanism is used for stopping a second row of sample racks adjacent to the first row of sample racks after a first row of sample racks facing the conveying mechanism in the multiple rows of sample racks is pushed onto the conveying mechanism. By the method, the sample analysis equipment can push the foremost row of sample racks into the conveying mechanism and stop the second row of sample racks adjacent to the first row of sample racks from entering the conveying mechanism when a plurality of rows of sample racks are loaded, so that continuous loading of batch sample racks is realized, and the detection efficiency of the sample analysis equipment is improved.

Description

Sample analysis equipment
Technical Field
The application relates to the technical field of medical equipment, in particular to sample analysis equipment.
Background
In the field of medical instruments, sample analysis devices are commonly used to perform detection analysis on samples. The common detection process of the sample analysis device is as follows: and placing the sample rack provided with the plurality of sample test tubes into a loading area of the sample analysis equipment, and conveying the sample rack to a detection position by the sample analysis equipment through a loading mechanism and a conveying mechanism so as to carry out automatic detection.
In current sample analysis equipment, at sample analysis equipment with sample frame loading to conveying mechanism's in-process, can't realize continuous batch loading when loading the district and having the multirow test-tube rack to influence sample analysis equipment's detection efficiency.
Disclosure of Invention
The application provides a sample analysis device to solve the technical problem that continuous batch loading can not be realized by sample analysis devices.
In order to solve the above problems, the present application provides a sample analysis apparatus including a conveying mechanism, a loading mechanism, and a stopper mechanism; the conveying mechanism is used for conveying the sample rack to the detection position; the loading mechanism is used for pushing the whole sample rack with multiple rows to the conveying mechanism so that the sample racks with multiple rows can be pushed onto the conveying mechanism in sequence; the stopping mechanism is used for stopping a second row of sample racks adjacent to the first row of sample racks after a first row of sample racks closest to the conveying mechanism in the plurality of rows of sample racks is pushed onto the conveying mechanism.
The sample analysis device further comprises a bearing plate, wherein the bearing plate is provided with a supporting surface and used for placing a plurality of rows of sample racks, and the stopping mechanism is arranged at one end, facing the conveying mechanism, of the bearing plate and used for elastically abutting against the sample racks moving to the stopping mechanism.
The sample rack is provided with a bearing plate, the bearing plate is provided with a stopping mechanism, the stopping mechanism is arranged below the bearing plate and elastically abutted against the sample rack along the supporting direction of the bearing plate to the sample rack, and the bearing plate is provided with a limiting mechanism used for limiting the sample rack along the opposite direction of the supporting direction, so that the sample rack is still kept on the supporting surface after being elastically abutted by the stopping mechanism.
The bearing plate is provided with a through hole, the stopping mechanism comprises a mounting seat, a stopping block and a first elastic piece, the mounting seat is fixed below the bearing plate and is provided with a mounting cavity, the stopping block and the first elastic piece are arranged in the mounting cavity, and the stopping block is elastically supported by the first elastic piece, so that the end part of the stopping block is exposed out of the through hole and forms elastic butt with the bottom of the sample frame.
Wherein, the end part of the stop block is arranged in an arc surface.
The loading mechanism comprises a pusher dog assembly and a transmission assembly, and the transmission assembly is used for transmitting the pusher dog assembly to move close to or far away from the conveying mechanism; the pusher dog assembly has a first state and a second state, when the transmission assembly transmits the pusher dog assembly to move close to the conveying mechanism, the pusher dog assembly is in the first state and can form interference with the sample rack which is positioned between the pusher dog assembly and the conveying mechanism and is adjacent to the pusher dog assembly, so that the sample rack positioned between the pusher dog assembly and the conveying mechanism is pushed to the conveying mechanism; when the transmission assembly transmits the pusher dog assembly to move away from the conveying mechanism, the pusher dog assembly is in the second state and can further cross the sample rack positioned on one side, away from the conveying mechanism, of the pusher dog assembly.
The pusher dog assembly comprises a support frame, a pusher dog and a second elastic piece, the pusher dog is rotatably supported on the support frame, the second elastic piece is used for elastically biasing the pusher dog so as to enable the pusher dog assembly to be in the first state, when the transmission assembly transmits the pusher dog assembly to move away from the conveying mechanism, the pusher dog overcomes the elastic bias of the elastic piece to rotate under the action of the sample rack on one side, away from the conveying mechanism, of the pusher dog assembly, so that the pusher dog is switched to the second state, and automatically resets to the first state after crossing the sample rack on one side, away from the conveying mechanism, of the pusher dog assembly.
The sample analysis equipment further comprises a bearing plate, wherein the bearing plate is provided with a supporting surface, the sample rack is placed on the supporting surface, the bearing plate is provided with a slot extending along the transmission direction of the pusher dog assembly, the pusher dog assembly is arranged below the bearing plate, and when the pusher dog assembly is in the first state, at least part of the pusher dog extends out of the slot to the upper part of the bearing plate.
The pusher dog is towards one side of transmission assembly is hook-shaped setting, and then with be located pusher dog subassembly with between the conveying mechanism and with adjacent setting of pusher dog subassembly the sample frame joint, the pusher dog deviates from one side of transmission assembly is provided with the guide face, and then with be located the pusher dog subassembly is kept away from conveying mechanism one side the sample frame guides during the interact the pusher dog rotates.
The bearing plate is provided with a limiting mechanism, the limiting mechanism extends along the transmission direction of the pusher dog assembly and is used for limiting the sample rack along the direction opposite to the supporting direction of the bearing plate for the sample rack, the pusher dog assembly is provided with an initial position, the transmission assembly transmits the pusher dog assembly to move from the initial position to the conveying mechanism, when the pusher dog assembly is located at the initial position, one end, facing the initial position, of the limiting mechanism keeps a preset interval with the pusher dog assembly along the transmission direction of the pusher dog assembly, and the preset interval is larger than the stroke of the sample rack along the transmission direction of the pusher dog assembly.
The present application provides a sample analysis device that includes a transport mechanism, a loading mechanism, and a stop mechanism. The conveying mechanism is used for conveying the sample rack to the detection position; the loading mechanism is used for pushing the multi-row sample racks to the conveying mechanism integrally so that the multi-row sample racks can be pushed to the conveying mechanism in sequence; the stopping mechanism is used for stopping a second row of sample racks adjacent to the first row of sample racks after a first row of sample racks closest to the conveying mechanism in the plurality of rows of sample racks is pushed into the conveying mechanism. By the method, the sample analysis equipment can push the first row of sample racks into the conveying mechanism and stop the second row of sample racks adjacent to the first row of sample racks from entering the conveying mechanism when the plurality of rows of sample racks are loaded, so that continuous loading of batch sample racks is realized, and the detection efficiency of the sample analysis equipment is improved.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Wherein:
FIG. 1 is a schematic diagram of an embodiment of a sample analysis device provided herein;
FIG. 2 is a schematic view of the structure of the loading mechanism of FIG. 1;
FIG. 3 is a schematic structural diagram of an embodiment of a loading mechanism provided herein;
FIG. 4 is a schematic structural view of the stop mechanism of FIG. 3;
FIG. 5 is a schematic structural view of another embodiment of a loading mechanism provided herein;
FIG. 6 is a schematic structural view of the finger assembly of FIG. 5 in a second state;
fig. 7 is a schematic view of the structure of the finger of fig. 6.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, embodiments accompanying the present application are described in detail below with reference to the accompanying drawings. It is to be understood that the specific embodiments described herein are merely illustrative of the application and are not limiting of the application. It should be further noted that, for the convenience of description, only some of the structures related to the present application are shown in the drawings, not all of the structures. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The terms "first", "second", etc. in this application are used to distinguish between different objects and not to describe a particular order. Furthermore, the terms "include" and "provided," as well as any variations thereof, are intended to cover non-exclusive inclusions. For example, a process, method, system, article, or apparatus that comprises a list of steps or elements is not limited to only those steps or elements listed, but may alternatively include other steps or elements not listed, or inherent to such process, method, article, or apparatus.
Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.
This application has at first proposed a sample analysis equipment, and this sample analysis equipment is applied to medical treatment or biochemical analysis field for carry out the autoinjection to the test-tube rack of placing the sample test tube and detect. A more common sample analysis device may be an immunoassay device; the sample analysis device may also be other clinical laboratory equipment.
Referring to fig. 1-2, fig. 1 is a schematic structural diagram of an embodiment of a sample analysis apparatus provided in the present application, and fig. 2 is a schematic structural diagram of a loading mechanism in fig. 1. As shown in fig. 1-2, the sample analysis apparatus 10 of the present application includes a platform floor 110, a transport mechanism 210, a loading mechanism 310, a catch mechanism 410, and an unloading mechanism 510.
The transport mechanism 210, the loading mechanism 310, and the unloading mechanism 510 are all mounted on the platform floor 110. The stopper mechanism 410 is provided to the loading mechanism 310, and the loading mechanism 310 and the unloading mechanism 510 are provided in this order in the conveying direction of the conveying mechanism 210, and are provided to the conveying mechanism 210 on the same side.
The conveying mechanism 210 is used for conveying the sample rack 311 to the detection position; the loading mechanism 310 is configured to push the multi-row sample rack 311 toward the conveying mechanism 210 in its entirety, so that the multi-row sample rack 311 can be sequentially pushed onto the conveying mechanism 210; the stopping mechanism 410 is used for stopping a second row of sample holders 311 adjacent to the first row of sample holders 311 after the first row of sample holders 311 closest to the conveying mechanism 210 in the plurality of rows of sample holders 311 is pushed onto the conveying mechanism 210; the unloading mechanism 510 is used to unload the sample rack 311 whose detection is completed.
The loading mechanism 310 includes a sample loading area for placing the plurality of rows of sample racks 311, the loading mechanism 310 pushes the plurality of rows of sample racks 311 of the sample loading area toward the conveying mechanism 210 as a whole, and the sample racks 311 in the plurality of rows of sample racks 311 are sequentially pushed into the conveying mechanism 210 by the loading mechanism 310. After the first row of sample racks 311 closest to the conveying mechanism 210 among the plurality of rows of sample racks 311 is pushed into the conveying mechanism 210, the stopping mechanism 410 stops the second row of sample racks 311 adjacent to the first row of sample racks 311, so as to prevent the second row of sample racks 311 from intruding into the conveying mechanism 210 due to inertia and prevent collision accidents such as collision of the sample racks.
Further, the sample analysis apparatus 10 further comprises a detection mechanism 610, wherein the detection mechanism 610 is used for detecting whether the sample rack 311 exists in the sample loading area of the loading mechanism 310. The sample analyzer 10 acquires a detection signal from the detection mechanism 610, and if the sample rack 311 is present in the loading mechanism 310, the sample analyzer 10 controls the loading mechanism 310 to start operating, and the loading mechanism 310 pushes the entire plurality of rows of sample racks 311 in the sample loading region toward the transport mechanism 210 to sequentially load the sample racks 311 onto the transport mechanism 210.
In an alternative embodiment, the detecting mechanism 610 includes two first detectors 611, the two first detectors 611 are disposed opposite to each other, one of the two first detectors 611 is disposed on a side of the conveying mechanism 210 away from the loading mechanism 310, and the other of the two first detectors 611 is disposed on a side of the loading mechanism 310 away from the conveying mechanism 210, so that the sample loading area is located between the two first detectors 611, and the two first detectors 611 can detect whether the sample rack 311 exists in the sample loading area. Specifically, the first detector 611 includes, but is not limited to, a photo-coupler detector.
In the present embodiment, the transport mechanism 210 of the sample analysis apparatus 10 is used to transport the sample rack 311 loaded on the transport mechanism 210 to the detection position; the loading mechanism 310 is configured to push the multi-row sample rack 311 toward the conveying mechanism 210 in its entirety, so that the sample racks 311 in the multi-row sample rack 311 can be sequentially pushed onto the conveying mechanism 210; the stopping mechanism 410 is used for stopping a second row of sample holders 311 adjacent to the first row of sample holders 311 after the first row of sample holders 311 closest to the conveying mechanism 210 in the plurality of rows of sample holders 311 is pushed onto the conveying mechanism 210. Different from the prior art, when the sample analysis device 10 loads a plurality of rows of sample racks 311, the sample rack 311 in the front row may be pushed into the conveying mechanism 210 and stop the second row of sample racks 311 adjacent to the first row of sample racks 311 from entering the conveying mechanism 210, so that the batch sample racks 311 are continuously loaded, and the detection efficiency of the sample analysis device 10 is improved.
Referring to fig. 3, fig. 3 is a schematic structural diagram of an embodiment of a loading mechanism provided in the present application. As shown in FIG. 3, the sample analysis device 10 of this embodiment further comprises a carrier plate 312, wherein the carrier plate 312 has a supporting surface on which sample loading areas are disposed for placing a plurality of rows of sample holders 311.
The stopping mechanism 410 is disposed on the carrier plate 312, and is disposed on a side of the carrier plate 312 opposite to the sample holder 311 and an end close to the conveying mechanism 210. The loading mechanism 310 pushes the entire multi-row sample rack 311 of the sample loading area toward the conveying mechanism 210, a first row of sample racks 311 of the multi-row sample racks 311 facing the conveying mechanism 210 is pushed into the conveying mechanism 210, a second row of sample racks 311 adjacent to the first row of sample racks 311 moves to the stopping mechanism 410, and the stopping mechanism 410 and the second row of sample racks 311 form elastic abutment.
After the first row of sample racks 311 enters the testing position of the sample analyzer 10 through the transportation mechanism 210 and the testing is completed, the sample analyzer 10 controls the stopping mechanism 410 to retract, the second row of sample racks 311 overcomes the elasticity of the stopping mechanism 410, and the second row of sample racks 311 continues to be pushed into the transportation mechanism 210 by the loading mechanism 310, so that the loading mechanism 310 continuously loads the sample racks 311.
Different from the prior art, the stopping mechanism 410 of the present embodiment is disposed at one end of the carrier plate 312 facing the conveying mechanism 210, and is configured to elastically abut against the sample rack 311 moving to the stopping mechanism 410, so that when a plurality of rows of sample racks 311 are loaded, the loading mechanism 310 can push the sample rack 311 at the front row into the conveying mechanism 210, and the stopping mechanism 410 stops the second row of sample racks 311 adjacent to the first row of sample racks 311 from entering the conveying mechanism 210, thereby realizing continuous loading of the batch sample racks 311 of the sample analysis device 10, and improving the detection efficiency of the sample analysis device 10.
Optionally, the stopping mechanism 410 is disposed below the carrier plate 312, and elastically abuts against the sample rack 311 along the supporting direction of the carrier plate 312 to the sample rack 311, and the carrier plate 312 is provided with a position limiting mechanism 313 for limiting the position of the sample rack 311 along the direction opposite to the supporting direction, so that the sample rack 311 is still kept on the supporting surface after being elastically abutted by the stopping mechanism 410.
The stopping mechanism 410 is disposed below the carrier plate 312 and along the supporting direction of the carrier plate 312 to the sample rack 311, and the stopping mechanism 410 is elastically abutted against the sample rack 311, so that the stopping mechanism 410 stops the sample rack 311. In order to reduce the influence of the elastic force of the stopping mechanism 410 in the supporting direction on the stability of the sample rack 311, the bearing plate 312 is further provided with a limiting mechanism 313, and the limiting mechanism 313 is used for limiting the sample rack 311 in the direction opposite to the supporting direction, so that the sample rack 311 is ensured to be kept on the supporting surface after being elastically abutted by the stopping mechanism 410, and the sample rack 311 is prevented from toppling due to the elastic abutment of the stopping mechanism 410.
In a specific embodiment, the limiting mechanism 313 may be disposed at a side of the loading plate 312, the limiting mechanism 313 includes a main body portion and an extension portion, the main body portion is disposed along the transmission direction of the loading mechanism 310, and the main body portion of the limiting mechanism 313 is connected to two sides of the loading plate 312; the extending portion is connected to the main body portion and extends toward the central axis of the carrier plate 312, and an included angle between the extending portion and the main body portion is about 90 ° to counteract the abutting force of the sample holder 311 along the supporting direction of the carrier plate 312. Further, the bottom of the sample holder 311 is provided with a positioning portion corresponding to the extending portion of the position-limiting mechanism 313 for matching with the position-limiting mechanism 313, so that the sample holder 311 is still kept on the supporting surface after being elastically abutted by the stopping mechanism 410.
Different from the prior art, the sample analysis device 10 of the present embodiment further includes a limiting mechanism 313, the stopping mechanism 410 forms an elastic abutment with the sample rack 311 along the supporting direction of the loading plate 312 to the sample rack 311, and the limiting mechanism 313 forms a limit to the sample rack 311 along the opposite direction of the supporting direction, so as to keep the sample rack 311 on the supporting surface when the stopping mechanism 410 elastically abuts against the sample rack 311, thereby preventing the sample rack 311 from toppling over due to the elastic abutment of the stopping mechanism 410, and improving the stability of the sample rack 311.
Referring to fig. 4, fig. 4 is a schematic structural view of the stop mechanism of fig. 3. As shown in fig. 4, a through hole 314 is formed in the carrier plate 312, the stopping mechanism 410 includes a mounting seat 411, a stopping block 412 and a first elastic member 413, and the stopping mechanism 410 is mounted in the through hole 314 of the carrier plate 312. The mounting seat 411 is fixed below the bearing plate 312, the mounting seat 411 is provided with a mounting cavity, and the stop block 412 and the first elastic element 413 of the stop mechanism 410 are disposed in the mounting cavity.
The loading mechanism 310 pushes the first row of sample racks 311 into the conveying mechanism 210, the first row of sample racks 311 passes through the through holes 314 of the bearing plate 312, the base of the first row of sample racks 311 acts on the stop block 412 under the pushing of the loading mechanism 310, the stop block 412 overcomes the elastic force of the first elastic piece 413 and sinks, the end of the stop block 412 is located in the through holes 314, and the end is flush with the bearing plate 312, so that the first row of sample racks 311 are pushed into the conveying mechanism 210 by the loading mechanism 310. After the first row of sample racks 311 are pushed into the conveying mechanism 210, the first elastic member 413 elastically supports the stop block 412, the end of the stop block 412 is exposed from the through hole 314, and the exposed end of the stop block 412 elastically abuts against the bottom of the second row of sample racks 311 to stop the second row of sample racks 311, so that the sample racks 311 are continuously loaded.
Different from the prior art, the stopping mechanism 410 of the present embodiment includes a mounting seat 411, a stopping block 412 and a first elastic member 413, the mounting seat 411 is fixed below the bearing plate 312, the mounting seat 411 is provided with a mounting cavity, the stopping block 412 and the first elastic member 413 are disposed in the mounting cavity, and the first elastic member 413 elastically supports the stopping block 412 so that the end of the stopping block 412 is exposed from the through hole 314 to form a stop for the sample holder 311. The stopper mechanism 410 of the present embodiment has a simple structure, is easy to implement, can save the installation space of the stopper mechanism 410, and is advantageous for the miniaturization of the sample analysis apparatus 10.
Further, the end of the stop block 412 is disposed in an arc. In particular embodiments, the end of the stop block 412 may be provided in a spherical shape, or may be provided in other arcuate shapes.
The end of the stop block 412 is an arc surface, when the end of the stop block 412 is in contact with the first row of sample racks 311, the stop block 412 can quickly overcome the elastic force of the first elastic piece 413 and sink, and the sample racks 311 are quickly switched from the loading state to the stopped state; after the first row of sample racks 311 is pushed into the conveying mechanism 210, the end of the stopper 412 can be quickly exposed from the through hole 314, and the sample racks 311 are quickly switched from the stopped state to the loading state; the arc-shaped end of the stop block 412 can improve the loading fluency of the loading mechanism 310 and the loading efficiency of the loading mechanism 310.
Referring to fig. 5, fig. 5 is a schematic structural diagram of another embodiment of the loading mechanism provided in the present application. As shown in fig. 5, the loading mechanism 310 includes a finger assembly 320 and a drive assembly 330, the finger assembly 320 being configured to abut the sample rack 311, and the drive assembly 330 being configured to drive the finger assembly 320 toward or away from the transport mechanism 210 so that a batch of sample racks 311 is loaded onto the transport mechanism 210.
Finger assembly 320 has a first state and a second state; when drive assembly 330 drives pawl assembly 320 to move closer to conveyor mechanism 210, pawl assembly 320 is in a first state; when drive assembly 330 drives pawl assembly 320 away from conveyor mechanism 210, pawl assembly 320 is in the second state; the loading mechanism 310 is configured to continuously load the batch of sample racks 311 onto the transport mechanism 210 by switching the finger assembly 320 between the first state and the second state.
When the finger assembly 320 is in the first state, the sample rack 311 is located between the finger assembly 320 and the transport mechanism 210, and the sample rack 311 is adjacent to the finger assembly 320. When the driving assembly 330 drives the finger assembly 320 to move close to the conveying mechanism 210, the finger assembly 320 can form interference with the sample rack 311 to push the sample rack 311 located between the finger assembly 320 and the conveying mechanism 210 toward the conveying mechanism 210.
When the finger assembly 320 is in the second state, the sample rack 311 is located on a side of the finger assembly 320 remote from the transport mechanism 210. At this point, the drive assembly 330 drives the finger assembly 320 away from the transport mechanism 210, and the finger assembly 320 is able to pass over the sample holder 311. After the finger assembly 320 passes over the sample rack 311, the sample rack 311 is transferred between the finger assembly 320 and the transport mechanism 210 by the transfer assembly 330, and the finger assembly 320 is reset to the first state.
When the sample racks 311 comprise at least two rows, the first row of sample racks 311 is located between the finger assembly 320 and the conveying mechanism 210, the transmission assembly 330 transmits the finger assembly 320 to move close to the conveying mechanism 210, and the finger assembly 320 is in the first state to push the first row of sample racks 311 to the conveying mechanism 210; the second row of sample racks 311 is located on the side of the pusher assembly 320 away from the transport mechanism 210, the driving assembly 330 drives the pusher assembly 320 to move away from the transport mechanism 210, the pusher assembly 320 is in the second state and passes over the second row of sample racks 311, the second row of sample racks 311 is transferred between the pusher assembly 320 and the transport mechanism 210 by the driving assembly 330, the pusher assembly 320 is reset to the first state, and the second row of sample racks 311 continues to be pushed toward the transport mechanism 210.
Unlike the prior art, loading mechanism 310 of the present embodiment includes a finger assembly 320 and a transmission assembly 330, finger assembly 320 having a first state and a second state; in the first state, the pusher assembly 320 can push the sample rack 311 located between the pusher assembly 320 and the transport mechanism 210 toward the transport mechanism 210; in the second state, finger assembly 320 passes over sample rack 311 on the side of finger assembly 320 remote from transport mechanism 210. The loading mechanism 310 of the present embodiment can continuously load the batch of sample racks 311 to the transport mechanism 210 by switching the state of the finger assembly 320, improving the detection efficiency of the sample analysis apparatus 10.
Referring to fig. 6, fig. 6 is a structural schematic diagram of the finger assembly in fig. 5 in a second state. As shown in fig. 6, the finger assembly 320 includes a supporting frame 321, a finger 322, and a second elastic member 323. The pusher dog 322 is rotatably supported on the supporting frame 321, and one end of the second elastic element 323 is connected to the pusher dog 322, and the other end is connected to the supporting frame 321.
The second elastic member 323 elastically biases the finger 322. The driving assembly 330 drives the pusher assembly 320 to move close to the conveying mechanism 210, the sample rack 311 is located between the pusher assembly 320 and the conveying mechanism 210 and adjacent to the pusher assembly 320, and the elastic bias of the second elastic member 323 enables the pusher assembly 320 to be in the first state.
After the first row of sample racks 311 is loaded, the driving assembly 330 drives the finger assembly 320 to move away from the conveying mechanism 210, and the second row of sample racks 311 is located on the side of the finger assembly 320 away from the conveying mechanism 210. The finger 322 is rotated against the elastic bias of the second elastic member 323 by the sample rack 311 located on the side of the finger assembly 320 remote from the transport mechanism 210, and is switched to the second state. Finger assembly 320 automatically resets to the first state after finger assembly 320 clears a sample rack 311 located on the side of finger assembly 320 remote from transport mechanism 210.
Different from the prior art, the finger assembly 320 has one end connected to the finger 322 and the other end connected to the supporting frame 321 through the second elastic element 323. When the sample rack 311 is located between the finger assembly 320 and the conveying mechanism 210 and is adjacent to the finger assembly 320, the finger 322 can keep the finger assembly 320 in the first state under the elastic bias of the second elastic member 323; when the sample rack 311 is located on the side of the finger assembly 320 remote from the transport mechanism 210, the finger 322 is rotated against the elastic bias of the second elastic member 323 by the sample rack 311 to switch the finger assembly 320 to the second state. The pusher dog assembly 320 of the present embodiment can switch the state of the pusher dog assembly 320 by the second elastic member 323 to continuously load the batch of sample racks 311 to the conveying mechanism 210, and the structure is simple and easy to implement.
Optionally, the sample analysis device 10 further comprises a carrier plate 324, wherein the carrier plate 324 has a supporting surface, and the supporting surface is provided with sample loading areas for placing the plurality of rows of sample holders 311.
Bearing plate 324 is provided with a slot extending along the transmission direction of finger assembly 320, and finger assembly 320 is disposed below bearing plate 324. When finger assembly 320 is in the first state, as shown in FIG. 5, fingers 322 extend at least partially out of the slots above carrier plate 324. When finger assembly 320 is in the second state, finger 322 is positioned entirely below carrier plate 324 such that finger assembly 320 can pass over sample rack 311 on the side of finger assembly 320 remote from transport mechanism 210.
Further, referring to fig. 7, fig. 7 is a schematic structural view of the finger shown in fig. 6. As shown in fig. 7, side of finger 322 facing transmission assembly 330 is hooked, and side of finger 322 facing away from transmission assembly 330 is provided with a guide surface.
When the pusher assembly 320 is in the first state, the driving assembly 330 drives the pusher 322 to move close to the conveying mechanism 210, the sample rack 311 is located between the pusher assembly 320 and the conveying mechanism 210 and is adjacent to the pusher assembly 320, and one side of the pusher 322, which is arranged in a hook shape, is clamped with the sample rack 311 to push the sample rack 311 to the conveying mechanism 210.
When the pusher dog assembly 320 is in the second state, the transmission assembly 330 transmits the pusher dog 322 to move away from the conveying mechanism 210, the sample rack 311 is located on one side of the pusher dog assembly 320 away from the conveying mechanism 210, one side of the pusher dog 322 provided with the guide surface interacts with the sample rack 311, the pusher dog 322 overcomes the elastic bias of the second elastic member 323, the sample rack 311 guides the pusher dog 322 to rotate, so that the part of the pusher dog 322 extending out of the slot to the upper part of the bearing plate 324 is not exposed out of the bearing plate 324 in the first state, and the pusher dog 322 can pass over the sample rack 311.
Different from the prior art, the side of the finger 322 facing the transmission assembly 330 is in a hook shape, and the side of the finger 322 facing away from the transmission assembly 330 is provided with a guide surface. When the sample rack 311 is located between the finger assembly 320 and the conveying mechanism 210 and is adjacent to the finger assembly 320, one hook-shaped side of the finger 322 is clamped with the sample rack 311 to push the sample rack 311 to the conveying mechanism 210; when sample holder 311 is located on the side of finger assembly 320 away from transport mechanism 210, the side of finger 322 provided with the guide surface interacts with sample holder 311, and sample holder 311 guides rotation of finger 322 so that finger 322 can pass over sample holder 311. In this embodiment, by forming the two sides of the pusher 322 in different shapes, the pusher 322 can perform different functions when the sample rack 311 is located on different sides of the pusher 322. When a sample rack 311 is located on the side of the finger assembly 320 remote from the transport mechanism 210, the finger 322 can be automatically retracted to allow loading of the next row of sample racks 311, enabling continuous loading of a batch of sample racks 311 of the sample analysis apparatus 10.
Further, the bearing plate 324 is provided with a limiting mechanism 325, and the limiting mechanism 325 extends along the transmission direction of the finger assembly 320 and is used for limiting the sample holder 311 along the direction opposite to the supporting direction of the bearing plate 324 to the sample holder 311. The specific structure of the limiting mechanism 325 is similar to that of the limiting mechanism 313 in the above embodiments, and is not described again.
Finger assembly 320 has an initial position that is either the beginning of movement of finger assembly 320 at which drive assembly 330 drives movement of finger assembly 320 toward conveyor mechanism 210 or the end of movement of finger assembly 320 at which drive assembly 330 drives movement of finger assembly 320 away from conveyor mechanism 210.
During the process of the transmission assembly 330 transmitting the movement of the finger assembly 320 from the initial position to the conveying mechanism 210, when the finger assembly 320 is at the initial position, one end of the limiting mechanism 325 facing the initial position is kept at a predetermined interval from the finger assembly 320 in the transmission direction of the finger assembly 320, and the predetermined interval is greater than the stroke of the sample rack 311 in the transmission direction of the finger assembly 320.
Specifically, when finger assembly 320 is in the first state and finger assembly 320 is in the initial position, the predetermined spacing between limit mechanism 325 and finger assembly 320 is greater than the travel of sample holder 311 in the driving direction of finger assembly 320, so that sample holder 311 does not interact with limit mechanism 325 in the initial position; while the driving assembly 330 drives the finger assembly 320 to move from the initial position to the conveying mechanism 210, the sample rack 311 is pushed by the finger assembly 320 to act on the limiting mechanism 325, and the limiting mechanism 325 limits the sample rack 311 along the direction opposite to the supporting direction of the bearing plate 324 to the sample rack 311, so as to ensure that the sample rack 311 is kept on the supporting surface during the loading process.
Alternatively, in any of the above embodiments, as shown in fig. 6, loading mechanism 310 includes a base for mounting stop mechanism 410, finger assembly 320, drive assembly 330, etc. The driving assembly 330 includes a timing belt 331 mounted to the base, a driving motor 332, and a guide 333.
Driving motor 332 is used for providing power, and hold-in range 331 is connected with driving motor 332's output shaft, and the support frame 321 of pusher dog subassembly 320 sets up in guide rail 333 and is connected with hold-in range 331, and when driving motor 332 drove hold-in range 331 and rotates, support frame 321 is along guide rail 333 reciprocating motion under the effect of hold-in range 331. The carrier plate 324 is disposed above the finger assembly 320, and the finger assembly 320 is close to or away from the conveying mechanism 210 under the action of the transmission assembly 330, so that the sample holders 311 on the carrier plate 324 are sequentially loaded into the conveying mechanism 210.
Optionally, the transport mechanism 210 of the sample analysis apparatus 10 includes a transport track, which may be, but is not limited to, a conveyor belt. The detecting mechanism 610 of the sample analyzer 10 further includes two second detectors 612, and the two second detectors 612 are oppositely disposed on the conveying track for detecting whether the sample rack 311 is loaded on the conveying mechanism 210, so as to ensure that the sample rack 311 is loaded in place. Specifically, the second detector 612 includes, but is not limited to, a photo-coupler detector.
Optionally, the sample analysis device 10 further comprises a code scanning mechanism for scanning the barcode of the sample rack 311 and the barcode of the sample test tube. Specifically, after the conveying mechanism 210 conveys the sample rack 311 to the detection position, before the sample analyzer 10 detects the sample tube, the barcode scanning mechanism identifies the barcode of the sample rack 311, the sample tube of the sample rack 311 sequentially passes through the code scanning position, and the barcode scanning mechanism scans the barcode of the sample tube to correspond the data of the sample tube to the detection data of the sample analyzer 10.
Optionally, the sample analysis device 10 further comprises a sampling module, a delivery module, a reagent module, a reaction module. When the device is used, the sample test tube is conveyed to the detection position of the sampling module through the loading mechanism 310, the sampling of the sampling module carries out quantitative sampling on the sample, and the sample is transferred to the reaction module to wait for reaction.
The reagent module is used for accommodating and preparing reagents required by sample detection, the conveying module conveys the reagents which need to be added into the samples to the reagent station, and the reagent needles of the reagent module absorb the corresponding reagents and accurately and quantitatively add the reagents into the reaction module so as to obtain the samples to be detected. The sample analysis device 10 performs a test on a sample to be tested to obtain test data. In particular embodiments, the test items of the sample analyzing device 10 include, but are not limited to, immunoassays, whole blood tests, and the like.
The above description is only for the purpose of illustrating embodiments of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings of the present application or are directly or indirectly applied to other related technical fields, are also included in the scope of the present application.

Claims (10)

1. A sample analysis apparatus, characterized in that the sample analysis apparatus comprises:
the conveying mechanism is used for conveying the sample rack to the detection position;
the loading mechanism is used for pushing the whole sample rack with multiple rows to the conveying mechanism so that the sample racks with multiple rows can be sequentially pushed onto the conveying mechanism;
and the stopping mechanism is used for forming a stopping function on a second row of sample racks adjacent to the first row of sample racks after a first row of sample racks closest to the conveying mechanism in the plurality of rows of sample racks is pushed onto the conveying mechanism.
2. The sample analyzing apparatus according to claim 1, further comprising a carrier plate having a supporting surface for placing the plurality of rows of sample holders, wherein the stopper mechanism is disposed at an end of the carrier plate facing the transport mechanism and is configured to elastically abut against the sample holders moved to the stopper mechanism.
3. The apparatus according to claim 2, wherein the stopping mechanism is disposed below the loading plate and elastically abuts against the sample rack along a supporting direction of the loading plate to the sample rack, and a position-limiting mechanism is disposed on the loading plate for limiting the position of the sample rack along a direction opposite to the supporting direction, so that the sample rack is still held on the supporting surface after being elastically abutted by the stopping mechanism.
4. The sample analyzer as claimed in claim 3, wherein the loading plate is provided with a through hole, the stopping mechanism comprises a mounting seat, a stopping block and a first elastic member, the mounting seat is fixed below the loading plate and is provided with a mounting cavity, the stopping block and the first elastic member are arranged in the mounting cavity, and the first elastic member elastically supports the stopping block, so that the end of the stopping block is exposed out of the through hole and elastically abuts against the bottom of the sample rack.
5. The sample analysis device of claim 4, wherein the end of the stop is cambered.
6. The sample analysis apparatus of claim 1, wherein the loading mechanism comprises a finger assembly and a transmission assembly for transmitting movement of the finger assembly towards or away from the transport mechanism;
the pusher dog assembly has a first state and a second state, and when the transmission assembly transmits the pusher dog assembly to move close to the conveying mechanism, the pusher dog assembly is in the first state and can form interference with the sample rack which is positioned between the pusher dog assembly and the conveying mechanism and is adjacent to the pusher dog assembly, so that the sample rack positioned between the pusher dog assembly and the conveying mechanism is pushed to the conveying mechanism;
when the transmission assembly transmits the pusher dog assembly to move away from the conveying mechanism, the pusher dog assembly is in the second state and can further cross the sample rack positioned on one side, away from the conveying mechanism, of the pusher dog assembly.
7. The sample analysis apparatus according to claim 6, wherein the finger assembly comprises a support frame, a finger rotatably supported on the support frame, and a second resilient member for resiliently biasing the finger such that the finger assembly is in the first state, wherein when the transmission assembly transmits the movement of the finger assembly away from the transport mechanism, the finger is rotated against the resilient bias of the second resilient member under the action of the sample rack on the side of the finger assembly away from the transport mechanism, thereby switching to the second state, and automatically returns to the first state after passing over the sample rack on the side of the finger assembly away from the transport mechanism.
8. The sample analysis device of claim 7, further comprising a carrier plate, wherein the carrier plate has a support surface, the sample rack is disposed on the support surface, the carrier plate has a slot extending along a driving direction of the finger assembly, the finger assembly is disposed below the carrier plate, and the finger at least partially protrudes from the slot to above the carrier plate when the finger assembly is in the first state.
9. The sample analysis device according to claim 8, wherein the pusher dog is hooked on a side facing the drive assembly and is clamped to the sample holder located between the pusher dog and the transport mechanism and adjacent to the pusher dog, and a guide surface is provided on a side of the pusher dog facing away from the drive assembly and guides the pusher dog to rotate when interacting with the sample holder located on a side of the pusher dog away from the transport mechanism.
10. The sample analyzer as claimed in claim 9, wherein the carrier plate is provided with a position-limiting mechanism, the position-limiting mechanism extends along the transmission direction of the pusher assembly and is used for limiting the position of the sample rack along the direction opposite to the supporting direction of the sample rack by the carrier plate; the pusher dog assembly is provided with an initial position, the transmission assembly transmits the pusher dog assembly to move from the initial position to the conveying mechanism, when the pusher dog assembly is at the initial position, one end of the limiting mechanism facing to the initial position keeps a preset interval with the pusher dog assembly along the transmission direction of the pusher dog assembly, and the preset interval is larger than the stroke of the sample rack along the transmission direction of the pusher dog assembly.
CN202210570515.XA 2022-05-24 2022-05-24 Sample analysis equipment Pending CN114660312A (en)

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