CN114641692B - 心血管风险事件预测及其用途 - Google Patents

心血管风险事件预测及其用途

Info

Publication number
CN114641692B
CN114641692B CN202080060080.3A CN202080060080A CN114641692B CN 114641692 B CN114641692 B CN 114641692B CN 202080060080 A CN202080060080 A CN 202080060080A CN 114641692 B CN114641692 B CN 114641692B
Authority
CN
China
Prior art keywords
subject
risk
biomarker
event
biomarkers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202080060080.3A
Other languages
English (en)
Chinese (zh)
Other versions
CN114641692A (zh
Inventor
迈克尔·辛特伯格
加尔吉·达塔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Private Placement Protein Body Operation Co ltd
Original Assignee
Private Placement Protein Body Operation Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Private Placement Protein Body Operation Co ltd filed Critical Private Placement Protein Body Operation Co ltd
Publication of CN114641692A publication Critical patent/CN114641692A/zh
Application granted granted Critical
Publication of CN114641692B publication Critical patent/CN114641692B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN202080060080.3A 2019-09-03 2020-09-02 心血管风险事件预测及其用途 Active CN114641692B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962895383P 2019-09-03 2019-09-03
US62/895,383 2019-09-03
PCT/US2020/048981 WO2021046074A1 (en) 2019-09-03 2020-09-02 Cardiovascular risk event prediction and uses thereof

Publications (2)

Publication Number Publication Date
CN114641692A CN114641692A (zh) 2022-06-17
CN114641692B true CN114641692B (zh) 2025-09-16

Family

ID=72521733

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080060080.3A Active CN114641692B (zh) 2019-09-03 2020-09-02 心血管风险事件预测及其用途

Country Status (11)

Country Link
US (1) US20220349904A1 (https=)
EP (1) EP4025916A1 (https=)
JP (2) JP7712913B2 (https=)
KR (1) KR20220057534A (https=)
CN (1) CN114641692B (https=)
AU (1) AU2020343243A1 (https=)
BR (1) BR112022003666A2 (https=)
CA (1) CA3151482A1 (https=)
IL (1) IL290951A (https=)
MX (1) MX2022002314A (https=)
WO (1) WO2021046074A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025173327A1 (ja) * 2024-02-14 2025-08-21 Ｎｅｃソリューションイノベータ株式会社 罹患死亡可能性予測モデル、罹患死亡可能性予測方法、罹患死亡可能性予測装置、プログラム、及び記録媒体

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102812359A (zh) * 2009-11-13 2012-12-05 Bg医药公司 心肌梗死的风险因子和预测
CN105765382A (zh) * 2013-08-09 2016-07-13 伊诺特伦公司 用于预测具有心血管疾病或心血管事件的风险的方法和试剂盒

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001577A (en) 1998-06-08 1999-12-14 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
US5705337A (en) 1990-06-11 1998-01-06 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US5763177A (en) 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
EP0786469B1 (en) 1990-06-11 2006-03-01 Gilead Sciences, Inc. Methods of use of nucleic acid ligands
US5580737A (en) 1990-06-11 1996-12-03 Nexstar Pharmaceuticals, Inc. High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
US6458539B1 (en) 1993-09-17 2002-10-01 Somalogic, Inc. Photoselection of nucleic acid ligands
US6242246B1 (en) 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
WO2008056034A1 (en) * 2006-11-10 2008-05-15 Hytest Ltd. Stable standards for bnp immunoassays
EP2302395B1 (en) * 2006-06-07 2015-04-15 Health Diagnostic Laboratory, Inc. Markers associated with arteriovascular events and methods of use thereof
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
DK2172566T4 (da) 2007-07-17 2022-06-13 Somalogic Inc Fremgangsmåde til generering af aptamerer med forbedrede off-rates
WO2012006632A2 (en) 2010-07-09 2012-01-12 Somalogic, Inc. Lung cancer biomarkers and uses thereof
EP2593566B1 (en) * 2010-07-14 2018-01-24 The Regents of The University of California Biomarkers for diagnosis of transient ischemic attacks
CN103429753A (zh) 2010-09-27 2013-12-04 私募蛋白质体公司 间皮瘤生物标记及其用途
MX373248B (es) * 2011-09-30 2020-05-11 Somalogic Operating Co Inc Prediccion de riesgo de evento cardiovascular y usos del mismo.
ES2792227T3 (es) * 2014-09-26 2020-11-10 Somalogic Inc Predicción de evento de riesgo cardiovascular y usos de la misma
CN108291330A (zh) * 2015-07-10 2018-07-17 西弗吉尼亚大学 卒中和卒中严重性的标志物

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102812359A (zh) * 2009-11-13 2012-12-05 Bg医药公司 心肌梗死的风险因子和预测
CN105765382A (zh) * 2013-08-09 2016-07-13 伊诺特伦公司 用于预测具有心血管疾病或心血管事件的风险的方法和试剂盒

Also Published As

Publication number Publication date
JP2025118715A (ja) 2025-08-13
JP2022546515A (ja) 2022-11-04
CN114641692A (zh) 2022-06-17
US20220349904A1 (en) 2022-11-03
MX2022002314A (es) 2022-06-02
AU2020343243A1 (en) 2022-03-10
CA3151482A1 (en) 2021-03-11
JP7712913B2 (ja) 2025-07-24
IL290951A (en) 2022-04-01
WO2021046074A1 (en) 2021-03-11
EP4025916A1 (en) 2022-07-13
KR20220057534A (ko) 2022-05-09
BR112022003666A2 (pt) 2022-05-24

Similar Documents

Publication Publication Date Title
CN116008563B (zh) 非酒精性脂肪肝疾病(nafld)和非酒精性脂肪性肝炎(nash)生物标记及其用途
JP2025118715A (ja) 心血管リスク／イベントの予測及びその使用
JP7766605B2 (ja) 非アルコール性脂肪性肝炎（ｎａｓｈ）のバイオマーカー及びその使用
JP7792338B2 (ja) 耐糖能異常障害を決定する方法
EP4232825B1 (en) Cardiovascular event risk prediction
HK40078070A (zh) 心血管风险事件预测及其用途
HK40095601A (zh) 心血管事件风险预测
HK40078070B (zh) 心血管风险事件预测及其用途
HK40129964A (en) Cardiovascular event risk prediction
CN118829884A (zh) 用于样品质量评估的方法
HK40074269A (en) Methods of determining impaired glucose tolerance
HK40090190A (zh) 非酒精性脂肪肝疾病(nafld)和非酒精性脂肪性肝炎(nash)生物标记及其用途
CN118765373A (zh) 用于样品质量评估的方法
CN118829883A (zh) 用于样品质量评估的方法
HK40078108A (en) Nonalcoholic steatohepatitis (nash) biomarkers and uses thereof
HK1259917A1 (en) Nonalcoholic fatty liver disease (nafld) and nonalcoholic steatohepatitis (nash) biomarkers and uses thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40078070

Country of ref document: HK

GR01 Patent grant
GR01 Patent grant