CN114641317A - 一种高生物利用度的7,8-二羟基黄酮复合纳米生物材料及其制备方法和用途 - Google Patents
一种高生物利用度的7,8-二羟基黄酮复合纳米生物材料及其制备方法和用途 Download PDFInfo
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Abstract
一种高生物利用度的7,8‑二羟基黄酮复合纳米生物材料及其制备方法和用途。具体地，所述材料以玉米醇溶蛋白和乳铁蛋白为包材，以7,8‑二羟基黄酮为芯材。所述材料具有高生物利用度、高脑靶向性、优异稳定性、良好贮藏稳定性、便于长期储存等优点。还公开了所述材料的制备和应用。
Description
PCT国内申请，说明书已公开。
Claims (10)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911087744 | 2019-11-08 | ||
| CN2019110877440 | 2019-11-08 | ||
| PCT/CN2020/127104 WO2021088983A1 (zh) | 2019-11-08 | 2020-11-06 | 一种高生物利用度的7,8-二羟基黄酮复合纳米生物材料及其制备方法和用途 |
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| Publication Number | Publication Date |
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| CN114641317A true CN114641317A (zh) | 2022-06-17 |
| CN114641317B CN114641317B (zh) | 2024-03-29 |
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| WO (1) | WO2021088983A1 (zh) |
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| US20230046078A1 (en) * | 2021-07-15 | 2023-02-16 | Emory University | Methods of using substituted flavones for treating bone disorders |
| CN114948869A (zh) * | 2022-05-26 | 2022-08-30 | 中国药科大学 | 一种染料木素纳米混悬液的制备方法及该方法制备的染料木素纳米混悬液 |
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| MOHAMMED S. ALQAHTANI ETAL.: "Food Protein Based Core−Shell Nanocarriers for Oral Drug Delivery: Effect of Shell Composition on in Vitro and in Vivo Functional Performance of Zein Nanocarriers", 《MOLECULAR PHARMACEUTICS》 * |
| YUFENG CHEN ETAL.: "7,8-Dihydroxyflavone nano-liposomes decorated by crosslinked and glycosylated lactoferrin: storage stability, antioxidant activity, in vitro release, gastrointestinal digestion and transport in Caco-2 cell monolayers", 《JOURNAL OF FUNCTIONAL FOODS》 * |
| YUFENG CHEN ETAL.: "Fabrication and characterization of zein/lactoferrin composite nanoparticles for encapsulating 7,8-dihydroxyflavone: Enhancement of stability, water solubility and bioaccessibility", 《INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES》 * |
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