CN114621831A - Water-soluble cleaning agent and preparation method and application thereof - Google Patents
Water-soluble cleaning agent and preparation method and application thereof Download PDFInfo
- Publication number
- CN114621831A CN114621831A CN202210325647.6A CN202210325647A CN114621831A CN 114621831 A CN114621831 A CN 114621831A CN 202210325647 A CN202210325647 A CN 202210325647A CN 114621831 A CN114621831 A CN 114621831A
- Authority
- CN
- China
- Prior art keywords
- cleaning agent
- water
- soluble cleaning
- antioxidant
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012459 cleaning agent Substances 0.000 title claims abstract description 120
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 44
- 230000000694 effects Effects 0.000 claims abstract description 27
- 239000002904 solvent Substances 0.000 claims abstract description 25
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 24
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 20
- 239000002736 nonionic surfactant Substances 0.000 claims abstract description 20
- 102000004190 Enzymes Human genes 0.000 claims abstract description 19
- 108090000790 Enzymes Proteins 0.000 claims abstract description 19
- 238000004140 cleaning Methods 0.000 claims abstract description 19
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 6
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 78
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical group CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims description 38
- 229960004063 propylene glycol Drugs 0.000 claims description 35
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 27
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 26
- 239000003963 antioxidant agent Substances 0.000 claims description 23
- 230000003078 antioxidant effect Effects 0.000 claims description 23
- 239000012071 phase Substances 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 18
- 108090000787 Subtilisin Proteins 0.000 claims description 14
- MRUAUOIMASANKQ-UHFFFAOYSA-N cocamidopropyl betaine Chemical compound CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O MRUAUOIMASANKQ-UHFFFAOYSA-N 0.000 claims description 14
- 229940073507 cocamidopropyl betaine Drugs 0.000 claims description 14
- PYIDGJJWBIBVIA-UYTYNIKBSA-N lauryl glucoside Chemical compound CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYIDGJJWBIBVIA-UYTYNIKBSA-N 0.000 claims description 14
- 229940048848 lauryl glucoside Drugs 0.000 claims description 14
- 235000013772 propylene glycol Nutrition 0.000 claims description 14
- 108091005804 Peptidases Proteins 0.000 claims description 13
- 239000004365 Protease Substances 0.000 claims description 13
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 13
- 108700004121 sarkosyl Proteins 0.000 claims description 11
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 11
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims description 11
- 150000001413 amino acids Chemical class 0.000 claims description 10
- 229910052708 sodium Inorganic materials 0.000 claims description 10
- 239000011734 sodium Substances 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims description 8
- 238000010438 heat treatment Methods 0.000 claims description 8
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims description 7
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 6
- 238000007599 discharging Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 125000002801 octanoyl group Chemical group C(CCCCCCC)(=O)* 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 4
- 229940051250 hexylene glycol Drugs 0.000 claims description 4
- 238000004519 manufacturing process Methods 0.000 claims description 4
- WLPORNKIACJZBO-UHFFFAOYSA-M potassium;2-(dodecanoylamino)acetate Chemical compound [K+].CCCCCCCCCCCC(=O)NCC([O-])=O WLPORNKIACJZBO-UHFFFAOYSA-M 0.000 claims description 4
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims description 3
- JDRSMPFHFNXQRB-CMTNHCDUSA-N Decyl beta-D-threo-hexopyranoside Chemical compound CCCCCCCCCCO[C@@H]1O[C@H](CO)C(O)[C@H](O)C1O JDRSMPFHFNXQRB-CMTNHCDUSA-N 0.000 claims description 3
- 229940073499 decyl glucoside Drugs 0.000 claims description 3
- 239000007791 liquid phase Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 2
- 229960003237 betaine Drugs 0.000 claims description 2
- -1 lauroyl propyl Chemical group 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims description 2
- 235000013336 milk Nutrition 0.000 abstract description 18
- 239000008267 milk Substances 0.000 abstract description 18
- 210000004080 milk Anatomy 0.000 abstract description 18
- 238000005202 decontamination Methods 0.000 abstract description 11
- 230000003588 decontaminative effect Effects 0.000 abstract description 11
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 230000007794 irritation Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 description 29
- 239000000243 solution Substances 0.000 description 23
- 235000013350 formula milk Nutrition 0.000 description 22
- 229940088598 enzyme Drugs 0.000 description 13
- 239000002994 raw material Substances 0.000 description 11
- 239000003599 detergent Substances 0.000 description 9
- 238000005406 washing Methods 0.000 description 9
- 230000000052 comparative effect Effects 0.000 description 8
- 239000006260 foam Substances 0.000 description 6
- 239000008213 purified water Substances 0.000 description 6
- 239000000843 powder Substances 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- FPVJYHHGNGJAPC-UHFFFAOYSA-N 2-[3-(decanoylamino)propyl-dimethylazaniumyl]acetate Chemical compound CCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O FPVJYHHGNGJAPC-UHFFFAOYSA-N 0.000 description 4
- 229940073742 capramidopropyl betaine Drugs 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000002791 soaking Methods 0.000 description 4
- 239000003795 chemical substances by application Substances 0.000 description 3
- 230000003749 cleanliness Effects 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 238000010998 test method Methods 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 230000003020 moisturizing effect Effects 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- KRGCGUNDVLXQFX-UHFFFAOYSA-N 4-oxopentadecyl hydrogen sulfate Chemical compound CCCCCCCCCCCC(=O)CCCOS(O)(=O)=O KRGCGUNDVLXQFX-UHFFFAOYSA-N 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000004851 dishwashing Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 125000000400 lauroyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/94—Mixtures with anionic, cationic or non-ionic compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0084—Antioxidants; Free-radical scavengers
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2003—Alcohols; Phenols
- C11D3/2041—Dihydric alcohols
- C11D3/2044—Dihydric alcohols linear
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38618—Protease or amylase in liquid compositions only
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/04—Carboxylic acids or salts thereof
- C11D1/10—Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/90—Betaines
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/92—Sulfobetaines ; Sulfitobetaines
-
- C11D2111/18—
Abstract
The invention relates to a water-soluble cleaning agent, a preparation method and application thereof, and belongs to the field of cleaning agents. The cleaning agent comprises the following components in percentage by mass: 0-3% of anionic surfactant, 2-15% of amphoteric surfactant, 0.2-5% of nonionic surfactant, 0.2-7% of solubilizer, 0.0006-0.3% of biological enzyme and the balance of water. The cleaning agent is particularly suitable for cleaning utensils with protein residues, such as milk bottles, has strong decontamination effect, has very low residue, is convenient to wash, has no toxic or side effect or irritation, and is safe to use.
Description
Technical Field
The invention relates to the field of cleaning agents, and particularly relates to a water-soluble cleaning agent and a preparation method and application thereof.
Background
The feeding bottle is an article which is necessary for infants to use every day, and the cleanliness of the feeding bottle is closely related to the physical health of the infants. The infant formula milk powder contains a large amount of protein, is easy to deteriorate when exposed to air, is troublesome to clean, is difficult to clean substances such as protein adhered to a bottle if cleaned by clean water, is inconvenient to scald by boiled water, and cannot ensure thorough sterilization.
In order to achieve good decontamination capability, a large amount of surfactant is usually added into the cleaning agent, but the skilled person generally believes that the addition of a large amount of surfactant causes difficulty in cleaning and easily causes cleaning agent residue, thereby causing harm to the health of infants. Therefore, at present, the nursing bottle cleaning agent is mostly studied in the direction of reducing the usage amount of the surfactant and ensuring the decontamination effect, so as to reduce the residue of the cleaning agent on the nursing bottle, thereby ensuring the health of the infant. The feeding bottle cleaning agent has low dosage of the surfactant, so if the surface active agent is used for removing dirt, the dirt removing effect is not ideal, other high-cost dirt removing agents are required to be added to achieve a good dirt removing effect, and the cost of the feeding bottle cleaning agent is high due to the fact that some cleaning agent components are complex.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a water-soluble cleaning agent, a preparation method and application thereof. The cleaning agent has strong decontamination effect, simultaneously has very low residue, is convenient to wash, has no toxic or side effect or stimulation, is safe to use, and has the effect of inhibiting the growth of microorganisms.
In order to achieve the purpose, the invention adopts the following technical scheme:
the invention provides a water-soluble cleaning agent, which comprises the following components in percentage by mass: 0-3% of anionic surfactant, 2-15% of amphoteric surfactant, 0.2-5% of nonionic surfactant, 0.2-7% of solubilizer, 0.0006-0.3% of biological enzyme and the balance of water.
In the cleaning agent, as a preferred embodiment, the content of each component in the cleaning agent by mass percentage satisfies at least one of the following conditions: 0.08-1% of anionic surfactant; 9 to 14.5 percent of amphoteric surfactant; 2-5% of nonionic surfactant; 1.3 to 4.6 percent of solubilizer; 0.005-0.05% of biological enzyme.
In the cleaning agent, as a preferred embodiment, the cleaning agent further comprises an antioxidant, and the antioxidant is 0.1-1% by mass; preferably, the antioxidant is p-hydroxyacetophenone; preferably, the mass percentage of the antioxidant in the cleaning agent is 0.3-0.6%.
In the above cleaning agent, as a preferred embodiment, the solubilizer comprises propylene glycol and/or hexylene glycol; preferably, the propylene glycol is 1, 2-propylene glycol; preferably, the hexanediol is 1, 2-hexanediol; more preferably, the solubilizer is 1, 2-propylene glycol and 1, 2-hexanediol, and the content of the 1, 2-propylene glycol and the content of the 1, 2-hexanediol in the cleaning agent are 0.1-5% and 0.1-2% by mass percent.
In the cleaning agent, as a preferable embodiment, in the cleaning agent, the content of the 1, 2-propylene glycol is 1 to 4% by mass, and the content of the 1, 2-hexanediol is 0.3 to 0.6% by mass.
In the above cleaning agent, as a preferred embodiment, the cleaning agent satisfies at least one of the following conditions:
the anionic surfactant comprises at least one of sodium lauroyl sarcosinate, potassium lauroyl glycinate, sodium cocoyl malic amino acid and sodium lauroyl oat amino acid;
the amphoteric surfactant comprises at least one of cocamidopropyl betaine, lauroyl propyl hydroxysultaine, cocamidohydroxysultaine, caprylyl/capramidopropyl betaine;
the nonionic surfactant includes at least one of lauryl glucoside and decyl glucoside.
In the above cleaning agent, as a preferred embodiment, the biological enzyme is a protease; preferably, the protease is subtilisin.
The second aspect of the present invention provides a method for preparing the cleaning agent, comprising the steps of:
s1, adding the anionic surfactant, the amphoteric surfactant and the nonionic surfactant into water according to the component ratio of the cleaning agent, heating and preserving heat under the stirring condition to obtain phase A solution;
s2, mixing the cooled A-phase solution with the solubilizer, stirring uniformly, continuously cooling to a temperature which does not influence the activity of the biological enzyme, adding the biological enzyme, continuously stirring uniformly, and discharging to obtain the cleaning agent;
when the antioxidant is added to the cleaning agent, the following operations are also required before the step S2 is performed: adding the antioxidant into a preheated solubilizer, stirring to dissolve the antioxidant uniformly and transparently to obtain a B-phase solution; and replacing the solubilizing agent in step S2 with a B-phase solution.
In the above production method, as a preferred embodiment, the production method satisfies at least one of the following conditions:
filtering is further included after the discharging in the step S2, and the filtering is performed by adopting a filter, so that the obtained liquid phase is the cleaning agent; preferably, the filter has a 500 mesh filter screen;
in step S1, the heating and heat preservation refers to heating to 75-85 ℃ and preserving heat at the temperature for 15-25 min;
in step S2, the temperature of the phase A solution is reduced to 55-65 ℃;
in the preparation of the B-phase solution, the temperature of the pre-preheated solubilizer is 55-65 ℃;
when the solubilizer is propylene glycol or hexanediol and the antioxidant is added to the cleaning agent, the following operations are required before the step S2 is performed: and adding the antioxidant and the hexanediol into pre-preheated propylene glycol, stirring, dissolving and uniformly stirring to obtain a B-phase solution.
The third aspect of the invention provides the use of the above cleaning agent or the above preparation method for preparing a cleaning agent for cleaning utensils with residual protein.
In the above application, preferably, the vessel comprises a baby bottle.
The technical characteristics of the invention can be combined into different technical schemes at will without conflict.
Compared with the prior art, the invention has the following beneficial effects:
(1) in the formula of the cleaning agent, at least two types of amphoteric surfactants and nonionic surfactants are preferably used in a matching way by combining three types of surfactants, namely anionic surfactants, amphoteric surfactants and nonionic surfactants according to a specific proportion, and a small amount of biological enzyme is added, particularly when the surfactants are sodium lauroyl sarcosinate, cocamidopropyl betaine and lauryl glucoside in a matching way, the cleaning agent has strong decontamination effect, and meanwhile, the residue of the cleaning agent on protein-residual utensils, particularly milk bottles is very low, so that the cleaning agent is very safe to the health of babies.
(2) In order to ensure the decontamination effect, the formula of the invention adopts a surfactant formula with a specific proportion, and the formula is reasonable and the proper surfactant is selected, so the cleaning agent of the invention has no high residue of the final cleaning agent on the milk bottle caused by higher content of the surfactant.
(3) Compared with the commercially available cleaning products for milk bottles, the cleaning agent has less residue on the milk bottles under the condition of the same content of the surfactant, the preferable formula can reach below 0.03 mu g/mL, the cleaning agent is basically negligible, the decontamination capability is optimal, and the cleaning agent is safest for babies.
(4) The formula of the invention is added with a proper amount of 1, 2-hexanediol, which not only has the function of moisturizing, but also has the function of increasing the solubility of active ingredients, has certain corrosion resistance, can also have the functions of inhibiting microorganisms and increasing the corrosion resistance when being used in combination with the p-hydroxyacetophenone, does not need to be additionally added with bacteriostasis, bacteriolysis or bactericide, and has the advantages of environmental protection, safety and long shelf life.
(5) The invention has the advantages of easily obtained raw materials, simple formula, pH of the obtained cleaning agent of 6-8, simple preparation and low cost.
Detailed Description
In order to make the technical solutions and advantages of the present invention more apparent, the following further detailed description of the exemplary embodiments of the present invention makes clear that the described embodiments are only a part of the embodiments of the present invention, rather than an exhaustive list of all embodiments, and features in the embodiments and embodiments in the present specification may be combined with each other without conflict.
The water-soluble cleaning agent provided by the invention comprises the following components in percentage by mass: 0-3% of anionic surfactant, 2-15% of amphoteric surfactant, 0.2-5% of nonionic surfactant, 0.2-7% of solubilizer, 0.0006-0.3% of biological enzyme and the balance of water.
The inventor unexpectedly finds that: when the surfactant at least comprising the amphoteric surfactant and the nonionic surfactant is selected and compounded according to a specific proportion, even if the total dosage of the surfactant is larger, the residual quantity on a utensil cannot be too large. The cleaning agent is characterized in that an amphoteric surfactant is used as a main surfactant, a proper amount of nonionic surfactant which does not exist in an ionic form in an aqueous solution is added, so that the detergency is guaranteed, the residual quantity of the surfactant can be prevented from being large, the cleaning agent is easy to clean even if the dosage of the surfactant in the cleaning agent is large, the residual quantity of the surfactant is very low, when a small amount of anionic surfactant is added, the foam of a cleaning solution is rich and stable, the decontamination effect can be improved, the residual quantity of the surfactant on a utensil can not be increased, the residual quantity can be below 0.07 mu g/mL, and the residual quantity of a cleaning agent formula is preferably below 0.03 mu g/mL.
In order to prolong the shelf life of the cleaning agent, the cleaning agent can further comprise an antioxidant, and the antioxidant is 0.1-1% (such as 0.2%, 0.4%, 0.6%, 0.8% or 0.9%) by mass percent; preferably, the antioxidant is p-hydroxyacetophenone, which has the effects of antisepsis and synergism, can also play the role of antioxidation, can promote the effects of other preservatives, and has good stability in high and low pH and temperature ranges.
Preferably, the cleaning agent comprises the following components in percentage by mass: 0.08-1% of anionic surfactant, 9-14.5% of amphoteric surfactant, 2-5% of nonionic surfactant, 1.3-4.6% of solubilizer, 0.005-0.05% of biological enzyme, 0.3-0.6% of antioxidant and the balance of water.
The anionic surfactant is preferably an amino acid type anionic surfactant, such as at least one of sodium lauroyl sarcosinate, potassium lauroyl glycinate, sodium cocoyl malic amino acid, sodium lauroyl oat amino acid: more preferably sodium lauroyl sarcosinate; the surfactant has good emulsifying, wetting, solubilizing, dispersing and foaming properties, and the foam is fine and durable. The anionic surfactant is present in an amount of 0 to 3 wt%, preferably 0.03 to 3 wt% (e.g., 0.04 wt%, 0.06 wt%, 0.08 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.5 wt%, 2 wt%, 2.5 wt%, or 2.8 wt%), and the addition of a lower amount of anionic surfactant ensures uniform dispersion of various surfactants in the detergent, good fluidity, easy water dispersion, and improved overall detergency, while the lower amount of anionic surfactant in the formulation of the present invention does not increase the residue of the ware surface detergent, preferably 0.08 to 1 wt%. The anionic surfactant is added in an excessive amount, which increases the residue of the detergent on the vessel such as a baby bottle.
The amphoteric surfactant can be at least one of cocamidopropyl betaine, lauroyl propyl hydroxysulfonic acid betaine, cocamidohydroxysulfobetaine and caprylyl/capramidopropyl betaine; preferably, the amphoteric surfactant is selected from cocamidopropyl betaine, which has good cleaning, lathering, conditioning and good compatibility with the anionic and nonionic surfactants selected for use in the present invention. The content of the amphoteric surfactant in the cleaning agent is 2 to 15 wt% (e.g., 3 wt%, 5 wt%, 7 wt%, 10 wt%, 12 wt% or 14 wt%), which is too low to ensure a detergency effect, preferably 9 to 14.5 wt%.
The nonionic surfactant is prepared from at least one of lauryl glucoside and decyl glucoside and renewable plant raw materials; the cleaning agent has low surface tension, good detergency, good foamability, and rich, fine and stable foam. The two surfactants selected by the invention have good compatibility, are easy to remove in the cleaning process and are not easy to adhere to the surface of a solid. The content of the nonionic surfactant in the cleaning agent is 0.2-5 wt% (such as 0.3 wt%, 0.5 wt%, 1 wt%, 1.5 wt%, 2 wt%, 2.5 wt%, 3 wt%, 3.5 wt%, 4 wt%, or 4.5 wt%), preferably 2-5 wt%, and the lauryl glucoside in the content can be cooperated with other types of surfactants to realize synergistic effect, so that the cleaning effect can be ensured, the residue on the feeding bottle is low, the cleaning effect cannot be ensured due to too low content, and under the condition of very low content, the dosage of other surfactants needs to be increased if the cleaning effect is ensured, so that the residue of the cleaning agent on the feeding bottle is high.
The solubilising agent according to the invention may be any solubilising agent conventional in the art, preferably propylene glycol and/or hexylene glycol; more preferably, the propylene glycol is 1, 2-propylene glycol and the hexylene glycol is 1, 2-hexylene glycol; further preferably, the solubilizer is 1, 2-propylene glycol and 1, 2-hexanediol, the 1, 2-propylene glycol content is 0.1-5% (e.g., 0.2%, 0.5%, 1%, 1.3%, 1.5%, 1.7%, 2%, 2.5%, 3%, 3.5%, 3.9%, 4.5%, 4.8%), and the 1, 2-hexanediol content is 0.1-2% (0.2%, 0.4%, 0.5%, 0.7%, 1%, 1.5%, 1.8%). More preferably, in the cleaning agent, the content of the 1, 2-propylene glycol is 1-4% by mass, and the content of the 1, 2-hexanediol is 0.3-0.6% by mass. In the cleaning agent of the present invention, the solubilizer is preferably 1, 2-propanediol, 1, 2-hexanediol; the propylene glycol has the characteristics of fat-soluble solvent, has strong permeability and large dissolving power, increases the solubility of the p-hydroxyacetophenone, and can be used as a stabilizing agent of the biological enzyme to prolong the storage time of the cleaning solution. The 1, 2-hexanediol has not only a moisturizing effect but also a preservative function, the p-hydroxyacetophenone can enhance the preservative effect of hexanediol, in addition, the 1, 2-hexanediol and the p-hydroxyacetophenone are combined to play a role in inhibiting microorganisms, and the p-hydroxyacetophenone is the most safe antioxidant at present. The invention does not need to additionally add a sterilization or bacteriolysis reagent. Both solubilizers may increase the solubility of the components of the cleaning solution in water.
The biological enzyme of the invention is preferably a protease; the protease is preferably subtilisin, and has good decomposition effect on stains on vessels such as milk bottles, and the surfactant disclosed by the invention has better removal effect on decomposition products of the protease, namely, the addition of the enzyme can promote the dissolution or decomposition of the surfactant on stains, and the addition of a small amount of the enzyme enhances the decontamination effect of the surfactant disclosed by the invention. The protease is food-grade protease, and is safe and reliable. The protease is added to the cleaning agent of the present invention in an amount of 0.0006 to 0.3 wt% (e.g., 0.0008 wt%, 0.001 wt%, 0.003 wt%, 0.006 wt%, 0.008 wt%, 0.01 wt%, 0.015 wt%, 0.02 wt%, 0.03 wt%, 0.04 wt%, 0.05 wt%, 0.07 wt%, 0.1 wt%, 0.2 wt%, 0.28 wt%), preferably 0.005 to 0.05 wt%. The protease of the invention does not need to be added in too much amount, which causes waste and is not beneficial to the coordination and synergy of the protease and the surfactant.
The water used in the formula of the cleaning agent is preferably distilled water or deionized water, so that the influence of ions in the water on the using effect of the surfactant in the cleaning agent is reduced.
The formula of the cleaning agent has strong decontamination effect, and enzyme preparations for removing fat, sugar and the like, such as lipase and carbohydrate hydrolase, do not need to be added particularly.
The dosage of each component in the formula of the cleaning agent is the dosage of a pure substance.
The formulation of the cleaning agent of the present invention may also include a small amount of sodium chloride from a commercial finished cocamidopropyl betaine formulation.
According to the mass percentage, the formula of the cleaning agent is more preferably as follows: 0.08-0.3% of anionic surfactant, 11-12.5% of cocamidopropyl betaine, 4-5% of lauryl glucoside, 2.5-3.5% of 1, 2-propylene glycol, 0.4-0.6% of 1, 2-hexanediol, 0.01-0.015% of subtilisin, 0.4-0.6% of p-hydroxyacetophenone and the balance of water; wherein the anionic surfactant is at least one of sodium lauroyl sarcosinate, potassium lauroyl glycinate, sodium cocoyl malic amino acid and sodium lauroyl oat amino acid.
The preparation method of the cleaning agent used in the following embodiment of the invention comprises the following steps:
s1, adding an anionic surfactant, an amphoteric surfactant and a nonionic surfactant into water, heating to 80 ℃, and keeping the temperature and stirring for 20 minutes to dissolve the anionic surfactant, the amphoteric surfactant and the nonionic surfactant to obtain an A-phase solution;
s2, adding p-hydroxyacetophenone and 1, 2-hexanediol into pre-heated 1, 2-propylene glycol at 60 ℃, and stirring to dissolve the mixture to obtain a B-phase solution;
and S3, adding the B phase solution into the A phase solution cooled to 60 ℃, continuously cooling to 40 ℃ after uniformly stirring, then adding protease, continuously stirring uniformly, discharging after sampling and inspecting, and filtering by a precision filter (the filter is a 500-mesh filter screen) to obtain a liquid phase, namely the cleaning agent.
The preparation of the cleaning agent can be completed in a liquid washing stirring pot, when the solution in the liquid washing stirring pot needs to be cooled, the pot jacket can be opened to cool circulating water for cooling, and when the solution needs to be heated, a steam valve can be opened for heating.
The pH value of the cleaning agent obtained by the method is 6-8, the pH value test method is that the cleaning agent and water are mixed according to the volume ratio of 1:10 at the temperature of 25 ℃, and the pH value of the mixed solution is 6-8.
The cleaning agent can be used for cleaning utensils with protein residues; the vessel can be made of ceramics, plastics, glass and the like; after the cleaning agent is used for cleaning the vessel, the residual amount of the surfactant on the vessel is very low, and the decontamination effect is good, so the cleaning agent is particularly suitable for cleaning the feeding bottle used by infants, and is safe and reliable.
When the cleaning agent is used for cleaning a milk bottle container, the cleaning agent can be directly placed in the milk bottle, then a small amount of water is added for cleaning, the milk bottle container is cleaned by clean water, the volume of the added cleaning agent can be 1-10mL, and the volume of the added small amount of water can be 5-20 times that of the cleaning agent; or preparing the cleaning agent and water into a soaking solution, then soaking the feeding bottle or other utensils to be cleaned in the soaking solution for 3-10min, and then washing the feeding bottle or other utensils to be cleaned with clear water, wherein the volume ratio of the cleaning agent to the water in the soaking solution is 1: 50-500.
The enzyme activity of subtilisin used in the examples below was 100 PRMU-U/g.
Example 1
According to the mass percentage, the raw material formula of the cleaning agent in the embodiment is as follows:
sodium lauroyl sarcosinate 0.3%, cocamidopropyl betaine 14.1%, lauryl glucoside 2.5%, 1, 2-propylene glycol 2%, 1, 2-hexanediol 0.4%, subtilisin 0.006%, p-hydroxyacetophenone 0.4%, and the balance water.
Example 2
The raw material formula of the cleaning agent in the embodiment is as follows:
sodium lauroyl sarcosinate 0.6%, cocamidopropyl betaine 11.75%, lauryl glucoside 2.5%, 1, 2-propanediol 3%, 1, 2-hexanediol 0.5%, subtilisin 0.012%, p-hydroxyacetophenone 0.5%, and balance water.
Example 3
The raw material formula of the cleaning agent in the embodiment is as follows:
0.9 percent of sodium lauroyl sarcosinate, 9.4 percent of cocamidopropyl betaine, 2.5 percent of lauryl glucoside, 3 percent of 1, 2-propylene glycol, 0.5 percent of 1, 2-hexanediol, 0.018 percent of subtilisin, 0.5 percent of p-hydroxyacetophenone and the balance of water.
Example 4
The raw material formula of the cleaning agent in the embodiment is as follows:
0.09% of sodium lauroyl sarcosinate, 11.75% of cocamidopropyl betaine, 4.5% of lauryl glucoside, 3% of 1, 2-propylene glycol, 0.5% of 1, 2-hexanediol, 0.012% of subtilisin, 0.5% of p-hydroxyacetophenone and the balance of water.
Example 5
The raw material formula of the cleaning agent in the embodiment is as follows:
sodium cocoyl malate or 0.3%, caprylyl/capramidopropyl betaine 11.75%, lauryl glucoside 4.5%, 1, 2-propylene glycol 3%, 1, 2-hexanediol 0.5%, subtilisin 0.012%, p-hydroxyacetophenone 0.5%, and water in balance.
Example 6
The raw material formula of the cleaning agent in the embodiment is as follows:
0.3 percent of lauroyl oat amino acid sodium, 11.75 percent of caprylyl/capramidopropyl betaine, 4.5 percent of lauryl glucoside, 3 percent of 1, 2-propylene glycol, 0.5 percent of 1, 2-hexanediol, 0.012 percent of subtilisin, 0.5 percent of p-hydroxyacetophenone and the balance of water.
Example 7
The raw material formula of the cleaning agent in the embodiment is as follows:
11.85% of cocamidopropyl betaine, 4.5% of lauryl glucoside, 3% of 1, 2-propylene glycol, 0.5% of 1, 2-hexanediol, 0.012% of subtilisin, 0.5% of p-hydroxyacetophenone and the balance of water.
Comparative example 1
The raw material formula of the cleaning agent of the comparative example is as follows:
11.75% of cocamidopropyl betaine, 3% of 1, 2-propylene glycol, 0.5% of 1, 2-hexanediol, 0.012% of subtilisin, 0.5% of p-hydroxyacetophenone and the balance of water.
Comparative example 2
The raw material formula of the cleaning agent of the comparative example is as follows:
sodium lauroyl sarcosinate 6%, cocamidopropyl betaine 8%, lauryl glucoside 1%, 1, 2-propylene glycol 3%, 1, 2-hexanediol 0.5%, subtilisin 0.012%, p-hydroxyacetophenone 0.5%, and water in balance.
The detergency and the bottle residue after washing of the detergents prepared in the above examples 1 to 7 and comparative examples 1 to 2 were examined.
Detergency testing method
According to method B2, method two foam method, in the determination of detergency in appendix B of GB9985-2000 "hand dishwashing detergents": a predetermined amount of artificial soil (10mL of bottled milk) was applied to dishes and washed in a dish detergent solution of a predetermined concentration (the solution was prepared by mixing 5mL of the detergent of the present invention with 2L of water), and the number of dishes washed was evaluated as the detergency, since the foam of the washing liquid was eliminated by the soil washed, the number of dishes washed by each detergent solution was correlated with the detergency thereof, and the end point of the washing was the disappearance of half of the surface foam. The results of the number of dishes tested by this method are shown in table 1 below:
TABLE 1 detergency test results
Secondly, a cleaning agent residue degree testing method 1:
1) the same amount of purified water was measured from 9 glass bottles of the same cleanliness, and the conductivity of the water in the 9 bottles was measured, and the bottles 1 to 7 were used for measuring the residual degrees of the cleaners of examples 1 to 7 of the present invention, and the bottles 1 'to 2' were used for measuring the residual degrees of the cleaners of comparative examples 1 to 2, respectively, and the data are shown in the following table 2:
TABLE 2 data for purified water in each of the same cleanliness vials
2) And then respectively adding milk powder with the same mass into each bottle, shaking the milk powder till the milk powder is uniformly dissolved, standing for half an hour, washing the milk bottle by using purified water and a cleaning agent with the same mass and the same quantity, adding the purified water with the same quantity as that in the step 1 into the milk bottle after washing, measuring the pH value of the water, determining the residual degree of the cleaning agent by using the conductivity, and comparing and analyzing the pH value data and the conductivity data with the purified water value tested in the step 1), wherein the closer the value is to the value of the purified water in the step 1), the less the residual quantity of the cleaning agent is shown, and the specific data are shown in a table 3.
TABLE 3 residual effect data of detergent after cleaning milk bottle soaked with milk powder
As can be seen from a comparison of the data in tables 2 and 3, the cleansers of examples 1 to 7 have low residual contents after washing the baby bottles, particularly the residual contents of the cleansers of examples 4 and 7 are the lowest, but the detergency of example 7 is slightly inferior to that of example 4 in comparison with example 7 in example 4. The cleaning agent of comparative example 1, although also low in residue, was poor in detergency.
Thirdly, a cleaning agent residue degree testing method 2:
the test method refers to GB/T24691-2009-fruit and vegetable cleaning agent appendix C. The examples 1-7 and comparative examples 1-2, as well as the commercially available Hirschmannine and babycare cleaners were tested for residue using this test method, and the results are shown in Table 4.
TABLE 4 cleaning agent residue test results
Claims (10)
1. The water-soluble cleaning agent is characterized by comprising the following components in percentage by mass: 0-3% of anionic surfactant, 2-15% of amphoteric surfactant, 0.2-5% of nonionic surfactant, 0.2-7% of solubilizer, 0.0006-0.3% of biological enzyme and the balance of water.
2. The water-soluble cleaning agent as claimed in claim 1, wherein the water-soluble cleaning agent comprises at least one of the following components in percentage by mass:
0.08-1% of anionic surfactant;
9 to 14.5 percent of amphoteric surfactant;
2-5% of nonionic surfactant;
1.3 to 4.6 percent of solubilizer;
0.005-0.05% of biological enzyme.
3. The water-soluble cleaning agent according to claim 1 or 2, wherein the water-soluble cleaning agent further comprises an antioxidant, and the antioxidant is 0.1-1% by mass; preferably, the antioxidant is p-hydroxyacetophenone; preferably, the mass percentage of the antioxidant in the cleaning agent is 0.3-0.6%.
4. The water soluble cleaner according to any one of claims 1 to 3, wherein the solubilizer comprises propylene glycol and/or hexylene glycol; preferably, the propylene glycol is 1, 2-propylene glycol; preferably, the hexanediol is 1, 2-hexanediol; more preferably, the solubilizer is 1, 2-propylene glycol and 1, 2-hexanediol, and the content of the 1, 2-propylene glycol and the content of the 1, 2-hexanediol in the water-soluble cleaning agent are 0.1-5% and 0.1-2% by mass percent.
5. The water-soluble cleaning agent according to claim 4, wherein the 1, 2-propanediol content is 1 to 4% and the 1, 2-hexanediol content is 0.3 to 0.6% by mass percentage in the water-soluble cleaning agent.
6. The water-soluble cleaning agent according to any one of claims 1 to 5, wherein the water-soluble cleaning agent satisfies at least one of the following conditions:
the anionic surfactant comprises at least one of sodium lauroyl sarcosinate, potassium lauroyl glycinate, sodium cocoyl malic amino acid and sodium lauroyl oat amino acid;
the amphoteric surfactant comprises at least one of cocamidopropyl betaine, lauroyl propyl hydroxysultaine, cocamidohydroxysultaine, caprylyl/capramimidopropyl betaine;
the nonionic surfactant includes at least one of lauryl glucoside and decyl glucoside.
7. The water-soluble cleaning agent according to any one of claims 1 to 6, wherein the biological enzyme is a protease; preferably, the protease is subtilisin.
8. The method for preparing the water-soluble cleaning agent according to any one of claims 1 to 7, comprising the steps of:
s1, adding the anionic surfactant, the amphoteric surfactant and the nonionic surfactant into water according to the component proportion of the water-soluble cleaning agent as set forth in any one of claims 1 to 7, heating and preserving heat under the stirring condition to obtain a phase A solution;
s2, mixing the cooled A-phase solution with the solubilizer, stirring uniformly, continuously cooling to a temperature which does not influence the activity of the biological enzyme, adding the biological enzyme, continuously stirring uniformly, and discharging to obtain the water-soluble cleaning agent;
when the antioxidant is added to the water-soluble cleaning agent, the following operations are also required before the step S2 is performed: adding the antioxidant into a preheated solubilizer, stirring to dissolve the antioxidant uniformly and transparently to obtain a B-phase solution; and replacing the solubilizing agent in step S2 with a phase B solution.
9. The production method according to claim 8, wherein the production method satisfies at least one of the following conditions:
filtering is further included after the discharging in the step S2, and the obtained liquid phase is the water-soluble cleaning agent after the filtering is carried out by adopting a filter; preferably, the filter has a 500 mesh filter screen;
in step S1, the heating and heat preservation refers to heating to 75-85 ℃ and preserving heat at the temperature for 15-25 min;
in step S2, the temperature of the phase A solution is reduced to 55-65 ℃;
in the preparation of the B-phase solution, the temperature of the pre-preheated solubilizer is 55-65 ℃;
when the solubilizer is propylene glycol or hexanediol and the antioxidant is added to the water-soluble cleaning agent, the following operations are required before the step S2 is performed: and adding the antioxidant and the hexanediol into pre-preheated propylene glycol, stirring, dissolving and uniformly stirring to obtain a B-phase solution.
10. Use of the water-soluble cleaning agent according to any one of claims 1 to 7 or the method according to any one of claims 8 to 9 for producing a cleaning agent for cleaning a vessel having residual protein; preferably, the vessel comprises a baby bottle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210325647.6A CN114621831B (en) | 2022-03-29 | 2022-03-29 | Water-soluble cleaning agent and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210325647.6A CN114621831B (en) | 2022-03-29 | 2022-03-29 | Water-soluble cleaning agent and preparation method and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114621831A true CN114621831A (en) | 2022-06-14 |
| CN114621831B CN114621831B (en) | 2023-10-31 |
Family
ID=81904722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210325647.6A Active CN114621831B (en) | 2022-03-29 | 2022-03-29 | Water-soluble cleaning agent and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114621831B (en) |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000072746A (en) * | 1999-12-06 | 2000-12-05 | 이상철 | A compound for disinfecting and washing a baby articles such as a nursing bottle |
| JP2005220200A (en) * | 2004-02-04 | 2005-08-18 | Lion Corp | Liquid detergent composition for nursing bottle |
| JP2011026467A (en) * | 2009-07-27 | 2011-02-10 | Nof Corp | Detergent composition |
| CN102660394A (en) * | 2012-05-09 | 2012-09-12 | 中航材航空新材料有限公司 | Water-based all-natural environment-friendly cleaning agent and preparation method thereof |
| JP2013166869A (en) * | 2012-02-16 | 2013-08-29 | Nof Corp | Cleaning agent composition for baby product |
| CN106635494A (en) * | 2015-10-30 | 2017-05-10 | 深圳市芭格美生物科技有限公司 | Bio-enzyme cleaning solution for milk bottle as well as preparation method and application of bio-enzyme cleaning solution |
| CN107929104A (en) * | 2017-12-25 | 2018-04-20 | 深圳市芭格美生物科技有限公司 | A kind of three-in-one wash and maintenance liquid of biology enzyme and preparation method thereof |
| CN108822972A (en) * | 2018-08-09 | 2018-11-16 | 福建樱幼佳科技有限公司 | Feeding bottle cleaning solution and preparation method and application |
| CN111690473A (en) * | 2019-03-11 | 2020-09-22 | 中国科学院青岛生物能源与过程研究所 | Tea saponin detergent for infants and preparation method thereof |
| CN111718804A (en) * | 2020-07-24 | 2020-09-29 | 上海绿瑞生物科技有限公司 | Foam type cleaning agent composition and application thereof |
| CN113088409A (en) * | 2021-02-24 | 2021-07-09 | 湖北研妆实业有限公司 | Milk bottle fruit and vegetable detergent and preparation method thereof |
-
2022
- 2022-03-29 CN CN202210325647.6A patent/CN114621831B/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000072746A (en) * | 1999-12-06 | 2000-12-05 | 이상철 | A compound for disinfecting and washing a baby articles such as a nursing bottle |
| JP2005220200A (en) * | 2004-02-04 | 2005-08-18 | Lion Corp | Liquid detergent composition for nursing bottle |
| JP2011026467A (en) * | 2009-07-27 | 2011-02-10 | Nof Corp | Detergent composition |
| JP2013166869A (en) * | 2012-02-16 | 2013-08-29 | Nof Corp | Cleaning agent composition for baby product |
| CN102660394A (en) * | 2012-05-09 | 2012-09-12 | 中航材航空新材料有限公司 | Water-based all-natural environment-friendly cleaning agent and preparation method thereof |
| CN106635494A (en) * | 2015-10-30 | 2017-05-10 | 深圳市芭格美生物科技有限公司 | Bio-enzyme cleaning solution for milk bottle as well as preparation method and application of bio-enzyme cleaning solution |
| CN107929104A (en) * | 2017-12-25 | 2018-04-20 | 深圳市芭格美生物科技有限公司 | A kind of three-in-one wash and maintenance liquid of biology enzyme and preparation method thereof |
| CN108822972A (en) * | 2018-08-09 | 2018-11-16 | 福建樱幼佳科技有限公司 | Feeding bottle cleaning solution and preparation method and application |
| CN111690473A (en) * | 2019-03-11 | 2020-09-22 | 中国科学院青岛生物能源与过程研究所 | Tea saponin detergent for infants and preparation method thereof |
| CN111718804A (en) * | 2020-07-24 | 2020-09-29 | 上海绿瑞生物科技有限公司 | Foam type cleaning agent composition and application thereof |
| CN113088409A (en) * | 2021-02-24 | 2021-07-09 | 湖北研妆实业有限公司 | Milk bottle fruit and vegetable detergent and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114621831B (en) | 2023-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107287046B (en) | Biological enzyme cleaning solution for infant clothes and preparation method thereof | |
| EP3046425B1 (en) | Fermented fruit solutions for cleaning compositions | |
| WO1998030673A1 (en) | Dishwashing method and detergent composition therefor | |
| CN106590984B (en) | A kind of concentrated tableware detergent | |
| JP5910912B2 (en) | Disinfectant cleaning composition | |
| CN105950312B (en) | A kind of garden stuff pesticide residue cleaning agent and preparation method thereof | |
| CN107267322A (en) | Degerming cleaning effervescent tablet of feeding bottle biology enzyme and its preparation method and application | |
| CN106929190A (en) | Cloth grass bio-enzyme cleaning agent and its preparation method and application | |
| KR101565097B1 (en) | liquid detergent composition | |
| CN110511826A (en) | It is a kind of to sterilize nontoxic machine dishwasher detergent and preparation method thereof | |
| EP1313832B1 (en) | Surfactant system | |
| CN114621831B (en) | Water-soluble cleaning agent and preparation method and application thereof | |
| CN106833946A (en) | Tableware biological enzyme cleaning fluid and its preparation method and application | |
| CN102994261B (en) | Fruit and vegetable cleansing milk containing mineral ions and method for preparing same | |
| JPH05117695A (en) | Cleaning composition for nursing bottle and tableware | |
| CN108676628A (en) | A kind of fabrics disinfectant detergent | |
| CN109825376A (en) | Dish washing liquid and preparation method thereof | |
| CN111139148A (en) | Milk bottle fruit and vegetable detergent and preparation method thereof | |
| CN109593615A (en) | A kind of preparation method of sodium bicarbonate detergent | |
| CN113897248B (en) | Degerming and mite-killing laundry detergent and preparation method thereof | |
| KR102296533B1 (en) | Detergent Composition Containing material for Oral cleaning and its Manufacturing Method | |
| KR102160437B1 (en) | Manufacturing method of cleaning agent containing seaweed extract and ionized water | |
| CN117264701A (en) | Food-grade spray detergent for degerming, decontaminating and removing pesticide residues of fruits, vegetables and tableware and preparation process thereof | |
| JPH0438795B2 (en) | ||
| CN116790325A (en) | Concentrated nonionic tableware detergent and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |