CN114617947A - 治疗母畜子宫蓄脓的中药处方及其制备方法 - Google Patents
治疗母畜子宫蓄脓的中药处方及其制备方法 Download PDFInfo
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Abstract
一种治疗母畜子宫蓄脓的中药处方，由以下重量份数的原料组成：金银花9‑14份，黄芩9‑15份，益母草8‑12份，元胡10‑15份，苍术8‑13份，干姜10‑15份，大蒜干20‑25份，车前草25‑30份，马齿苋8‑12份，当归8‑12份，败酱草10‑15份，紫草50‑150份，牛膝8‑12份，鱼腥草6‑12份。利用中药治疗母畜子宫蓄脓，具有提高非特异性免疫力、对细胞免疫和抗体形成有促进作用、抗感染作用明显、能激发机体抗感染的免疫功能、增强网状内皮系统的吞噬能力、减少抗药性、减少毒副作用、调节机体新陈代谢功能、减少治疗成本、降低经济损失、无药物残留等诸多的特点，治愈后不易复发。
Description
技术领域
本发明涉及一种治疗母畜子宫蓄脓的中药处方及其制备方法。
背景技术
随着我国畜牧业和居民生活水平的不断提高，人们对肉蛋奶等高蛋白产品需求逐年提高。另外，越来越多的人把饲养宠物作为人们寄托感情的一种方式。家畜和宠物饲养量逐年增加，随着集约化水平越来越高，动物疫病的发生对动物的机体健康和所提供的动物源性食品安全威胁也越来越大。母畜子宫蓄脓就是畜牧养殖和家庭饲养宠物的临床常见病之一。它是由于母畜子宫内膜囊样增生而导致荷尔蒙出现异常，这些子宫内膜的囊样构造受到细菌感染，产生大量分泌物，是母畜产后或流产后较常发生的一种生殖器官疾病，分为开放型和封闭型，多发于老年母畜。本病一年四季均可发病，无明显的季节性。症状表现为从阴门处有稀薄的黄褐色或者灰白色脓汁从阴道中排出，并往往黏附在阴门、尾根、飞节和大腿上，形成薄痂，阴部、腹部肿胀，下腹部明显下垂，同时也可常发生多饮、多尿、食欲不振、呕吐、腹泻等症状。子宫蓄脓的发病原因很多，常见的发病原因有发情后感染、配种感染、内分泌因素及卵巢疾病(卵巢囊肿、卵巢肿瘤)、周围组织器官的炎症造成子宫继发感染等。
本病发病机理非常复杂，发病时间较长，一般是由子宫内膜炎引起。通常是母畜进行分娩、人工授精、难产、难产手术、助产以及产褥期没有严格消毒或者操作不当形成损伤或者抵抗力降低，就会导致以上条件致病菌开始大量增殖，从而导致子宫内膜炎，进而发展为子宫蓄脓症。该病还与卵巢及血中含孕酮有关，由于母畜血中激素维持较高浓度，使子宫内膜抵抗力降低，导致大肠杆菌及其它细菌感染，引起子宫内膜炎，因炎症刺激造成子宫颈肥大或狭窄使子宫内渗出物不能排出，而蓄积子宫内。
临床常见的治疗方法之一是手术摘除子宫和卵巢，手术摘除子宫一般采用注射缩宫素和大剂量抗生素的方法杀菌消炎或促进子宫内脓血排出。虽然这种治疗方法能根除该疾病，但存在着手术风险，影响患畜的身体健康，同时这种治疗方法造成母畜绝育，严重影响了养殖者的经济效益和宠物饲养者的感情，而且增加饲料消耗和费用，造成巨大的经济损失，也会造成优质品系的传承受阻，制约了养殖业生产的正常发展。另一个常见的治疗方法是保守治疗，大剂量使用广谱抗生素配合抗厌氧菌药物，但是这样极易造成母畜对抗生素的耐药性和产品药残的超标，如果只依赖药物治疗封闭型的子宫蓄脓，可能因子宫破裂造成严重腹膜炎的可能性，且容易复发。
发明内容
鉴于以上情形，为了解决上述技术存在的问题，本发明提出一种治疗母畜子宫蓄脓的中药处方，利用中药治疗该病，具有提高非特异性免疫力、对细胞免疫和抗体形成有促进作用、抗感染作用明显、能激发机体抗感染的免疫功能、增强网状内皮系统的吞噬能力、减少抗药性、减少毒副作用、调节机体新陈代谢功能、减少治疗成本、降低经济损失、无药物残留等诸多的特点，治愈后不易复发。
一种治疗母畜子宫蓄脓的中药处方，由以下重量份数的原料组成：金银花9-14份，黄芩9-15份，益母草8-12份，元胡10-15份，苍术8-13份，干姜10-15份，大蒜干20-25份，车前草25-30份，马齿苋8-12份，当归8-12份，败酱草10-15份，紫草50-150份，牛膝8-12份，鱼腥草6-12份。
根据本申请的一种治疗母畜子宫蓄脓的中药处方，由以下重量份数的原料组成：金银花9-14g，黄芩9-15g，益母草8-12g，元胡10-15g，苍术8-13g，干姜10-15g，大蒜干20-25g，车前草25-30g，马齿苋8-12g，当归8-12g，败酱草10-15g，紫草50-150g，牛膝8-12g，鱼腥草6-12g。
根据本申请的一种治疗母畜子宫蓄脓的中药处方，制备方法在于：将全部原料混合，然后通过高速粉碎机进行超微处理，将原生药材的细胞壁完全打破，得到药粉。
进一步地，所述药粉处理为直径达到纳米级。
在采取本发明提出的技术后，根据本发明实施例的治疗母畜子宫蓄脓的中药处方及其制备方法，具有以下有益效果：将中药材原料混合后通过高速粉碎机超微处理后，将原生药材的细胞壁完全打破，药粉直径达到纳米级，能较好使原来的水不溶物质更好的在动物体内溶解、吸收、提高其吸收质量。利用中药治疗母畜子宫蓄脓，具有提高非特异性免疫力、对细胞免疫和抗体形成有促进作用、抗感染作用明显、能激发机体抗感染的免疫功能、增强网状内皮系统的吞噬能力、减少抗药性、减少毒副作用、调节机体新陈代谢功能、减少治疗成本、降低经济损失、无药物残留等诸多的特点，治愈后不易复发。
具体实施方式
下面将对本发明的优选的实施方式进行描述。提供以下的描述，以帮助对由权利要求及其等价物所限定的本发明的示例实施方式的理解。其包括帮助理解的各种具体细节，但它们只能被看作是示例性的。因此，本领域技术人员将认识到，可对这里描述的实施方式进行各种改变和修改，而不脱离本发明的范围和精神。而且，为了使说明书更加清楚简洁，将省略对本领域熟知功能或构造的详细描述。
一种治疗母畜子宫蓄脓的中药处方，由以下重量份数的原料组成：金银花9-14g，黄芩9-15g，益母草8-12g，元胡10-15g，苍术8-13g，干姜10-15g，大蒜干20-25g，车前草25-30g，马齿苋8-12g，当归8-12g，败酱草10-15g，紫草50-150g，牛膝8-12g，鱼腥草6-12g。
其制备方法在于：将全部原料混合，然后通过高速粉碎机进行超微处理，将原生药材的细胞壁完全打破，得到直径达到纳米级的药粉。
根据本发明的治疗母畜子宫蓄脓的中药处方及其制备方法，将中药材原料混合后通过高速粉碎机超微处理后，将原生药材的细胞壁完全打破，药粉直径达到纳米级，能较好使原来的水不溶物质更好的在动物体内溶解、吸收、提高其吸收质量。利用中药治疗母畜子宫蓄脓，具有提高非特异性免疫力、对细胞免疫和抗体形成有促进作用、抗感染作用明显、能激发机体抗感染的免疫功能、增强网状内皮系统的吞噬能力、减少抗药性、减少毒副作用、调节机体新陈代谢功能、减少治疗成本、降低经济损失、无药物残留等诸多的特点，治愈后不易复发。
根据本发明的治疗母畜子宫蓄脓的中药处方，其中药原料中：金银花性甘、寒，具有清热解毒，消炎退肿之功效，主治温病发热，热毒血痢，痈肿疔疮等多种感染性疾病；黄芩味苦，性寒，具有清热燥湿，泻火解毒，止血之功效，主治湿热痞满，泻痢，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒；益母草性苦、辛，微寒，具有活血调经，利尿消肿，清热解毒之功效，主治月经不调，痛经经闭，恶露不尽，水肿尿少，疮疡肿毒；元胡味辛、苦，性温。有活血散瘀，理气止痛的功能，主治痛经，经闭，症瘕，产后瘀阻，跌扑损伤，疝气作痛；苍术性味辛、苦，性温，具有燥湿健脾，祛风散寒的功效，主治湿阻中焦，脘腹胀满，泄泻，水肿，脚气痿蹙，风湿痹痛；干姜性味辛，性热，具有温中散寒，回阳通脉，温肺化饮之功效，主治脘腹冷痛，呕吐泄泻，肢冷脉微，寒饮喘咳；大蒜干中所含的硫化合物具有极强的抗菌消炎作用，对多种球菌、杆菌、真菌和病毒等都有抑制和杀灭作用，在目前发现的天然植物中，大蒜是抗菌作用最强的一种；车前草味甘，性寒，具有利尿、清热、明目、祛痰的功效，主治小便不通、淋浊、带下、尿血、黄疸、水肿、热痢、泄泻、鼻衄、目赤肿痛、喉痹、咳嗽、皮肤溃疡等；马齿苋味酸，性寒，具有清热解毒，凉血止血的功效，主要用于热痢脓血，热淋，带下病，痈肿恶疮；当归味甘、辛，性温，具有补血活血，调经止痛，润肠通便之功效，主治血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，风湿痹痛，跌扑损伤，痈疽疮疡；败酱草性凉，味辛、苦，具有清热解毒，祛痰排脓之功效，主治肠痈，肺痈，痢疾，产后瘀血腹痛，痈肿疔疮；紫草味甘、咸，性寒，有凉血，活血，解毒透疹之功效，主治痈疽便闭，血热毒盛，斑疹紫黑，麻疹不透，湿疹，疮疡；牛膝味苦、甘、酸，平，具有逐瘀通经，补肝肾，强筋骨，利尿通淋，引血下行之功效，主治经闭，痛经，腰膝酸痛，筋骨无力，淋证，水肿；鱼腥草味辛，微寒，有清热解毒，消痈排脓，利尿通淋之功效，主治肺痈吐脓，痰热喘咳，热痢，热淋，痈肿疮毒。
根据本发明的治疗母畜子宫蓄脓的中药处方中，金银花、黄芩、益母草、元胡为君药，充分发挥其清热解毒，化瘀止痛和直接抑制炎症的功效，辅以苍术、干姜、大蒜干、车前草、马齿苋、当归、败酱草、紫草、牛膝和鱼腥草为臣药，配之其消痈排脓、利湿止带、去腐生肌、带下、活血、产后瘀血腹痛、利尿通淋之功效，以达到彻底治愈母畜子宫蓄脓。
根据本发明的治疗母畜子宫蓄脓的中药处方，根据各味中草药的功效特点进行组方，具有清热燥湿、利湿止带、去腐生肌、抗菌消炎之功效，本发明是中药制剂，吸收快、药效迅速、有效成分含量高、服用量少、安全、无毒副作用。通过实验室抑菌试验得出如下表所示抑菌范围数据。
研成超微粉中药对临床菌株的抑菌范围(单位：mm)
利用根据本发明的治疗母畜子宫蓄脓的中药处方治疗该病，具有能提高患病母畜非特异性免疫力、对母畜细胞免疫和抗体形成有促进作用、抗感染作用明显、能激发母畜机体抗感染的免疫功能、增强母畜网状内皮系统的吞噬能力、减少抗药性、减少毒副作用、调节母畜机体新陈代谢功能、减少治疗成本、降低经济损失、无药物残留等诸多的特点，且治愈后不易复发。
该组中药处方在兽医门诊、规模种畜场经过五年的临床实践应用推广，获得了良好的治疗效果，取得了很好的经济效益和生态效益。以下是应用过程中与手术治疗和保守治疗方法治疗效果及效益对比分析：
数据表1：2015-2020年三种治疗肉用母牛子宫蓄脓方法对比
数据表2：2015-2020年三种治疗奶牛子宫蓄脓方法对比
数据表3：2015-2020年三种治疗母犬子宫蓄脓方法对比
以上对本发明进行了详细介绍，本文中应用了具体个例对本发明的原理及实施方式进行了阐述，以上实施例的说明只是用于帮助理解本发明的方法及其核心思想；同时，对于本领域的一般技术人员，依据本发明的思想，在具体实施方式及应用范围上均会有改变之处，综上所述，本说明书内容不应理解为对本发明的限制。
通过以上的实施方式的描述，本领域的技术人员可以清楚地了解到本发明可实施。当然，以上所列的情况仅为示例，本发明并不仅限于此。本领域的技术人员应该理解，根据本发明技术方案的其他变形或简化，都可以适当地应用于本发明，并且应该包括在本发明的范围内。
Claims (4)
1.一种治疗母畜子宫蓄脓的中药处方，其特征在于，由以下重量份数的原料组成：金银花9-14份，黄芩9-15份，益母草8-12份，元胡10-15份，苍术8-13份，干姜10-15份，大蒜干20-25份，车前草25-30份，马齿苋8-12份，当归8-12份，败酱草10-15份，紫草50-150份，牛膝8-12份，鱼腥草6-12份。
2.根据权利要求1所述的一种治疗母畜子宫蓄脓的中药处方，其特征在于，由以下重量份数的原料组成：金银花9-14g，黄芩9-15g，益母草8-12g，元胡10-15g，苍术8-13g，干姜10-15g，大蒜干20-25g，车前草25-30g，马齿苋8-12g，当归8-12g，败酱草10-15g，紫草50-150g，牛膝8-12g，鱼腥草6-12g。
3.根据权利要求1或2所述的一种治疗母畜子宫蓄脓的中药处方制备方法，其特征在于，将全部原料混合，然后通过高速粉碎机进行超微处理，将原生药材的细胞壁完全打破，得到药粉。
4.根据权利要求3所述的一种治疗母畜子宫蓄脓的中药处方制备方法，其特征在于，所述药粉处理为直径达到纳米级。
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